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https://www.readbyqxmd.com/read/27918443/human-intervention-study-to-assess-the-effects-of-supplementation-with-olive-leaf-extract-on-peripheral-blood-mononuclear-cell-gene-expression
#1
Anna Boss, Chi Hsiu-Juei Kao, Pamela M Murray, Gareth Marlow, Matthew P G Barnett, Lynnette R Ferguson
Olive leaf extract (OLE) has been used for many years for its putative health benefits, but, to date, scientific evidence for the basis of these effects has been weak. Although recent literature has described a link between ailments such as cardiovascular disease, diabetes and cancer and a protective effect of polyphenols in the OLE, the mode of action is still unclear. Here, we describe a double-blinded placebo (PBO)-controlled trial, in which gene expression profiles of peripheral blood mononuclear cells from healthy male volunteers (n = 29) were analysed to identify genes that responded to OLE, following an eight-week intervention with 20 mL daily consumption of either OLE or PBO...
December 2, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27910900/zn-uptake-behavior-of-rice-genotypes-and-its-implication-on-grain-zn-biofortification
#2
Sarah E Johnson-Beebout, Johnvie Bayang Goloran, Francis H C Rubianes, Jack D C Jacob, Oliver B Castillo
Understanding Zn uptake dynamics is critical to rice grain Zn biofortification. Here we examined soil Zn availability and Zn uptake pathways as affected by genotype (high-grain Zn varieties IR69428 and IR68144), Zn fertilization and water management in two pot experiments. Results showed significant interactions (P < 0.05) between genotypes and Zn fertilization on DTPA (diethylenetriaminepentaacetic acid)-extractable soil Zn from early tillering to flowering. DTPA-extractable Zn in soils grown with IR69428 was positively correlated with stem (r = 0...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27900540/a-novel-east-african-monopartite-begomovirus-betasatellite-complex-that-infects-vernonia-amygdalina
#3
Happyness G Mollel, Joseph Ndunguru, Peter Sseruwagi, Titus Alicai, John Colvin, Jesús Navas-Castillo, Elvira Fiallo-Olivé
The complete genomes of a monopartite begomovirus (genus Begomovirus, family Geminiviridae) and an associated betasatellite found infecting Vernonia amygdalina Delile (family Compositae) in Uganda were cloned and sequenced. Begomoviruses isolated from two samples showed the highest nucleotide sequence identity (73.1% and 73.2%) to an isolate of the monopartite begomovirus tomato leaf curl Vietnam virus, and betasatellites from the same samples exhibited the highest nucleotide sequence identity (67.1% and 68...
November 29, 2016: Archives of Virology
https://www.readbyqxmd.com/read/27882320/mediterrasian-diet-products-that-could-raise-hdl-cholesterol-a-systematic-review
#4
REVIEW
Mariangela Rondanelli, Attilio Giacosa, Paolo Morazzoni, Davide Guido, Mario Grassi, Gabriella Morandi, Chiara Bologna, Antonella Riva, Pietro Allegrini, Simone Perna
Background. High HDL-cholesterol (HDL-C) values are negatively correlated with cardiovascular diseases. This review analyses the effect of the supplementation with various Mediterranean diet products (artichoke, bergamot, and olive oil) and Asian diet products (red yeast rice) on the HDL-C value in dyslipidemic subjects. Methods. A systematic review has been done involving all the English written studies published from the 1st of January 1958 to the 31st of March 2016. Results. The results of this systematic review indicate that the dietary supplementation with red yeast rice, bergamot, artichoke, and virgin olive oil has promising effects on the increase of HDL-C serum levels...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27876915/effect-of-olive-leaf-satureja-khuzestanica-and-allium-sativum-extracts-on-giardia-lamblia-cysts-compared-with-metronidazole-in-vitro
#5
Sh Fallahi, A Rostami, B Delfan, Y Pournia, M Rashidipour
Giardia lamblia is one of the common causes of worldwide diarrhea in children. Appropriate medicinal treatment for giardiasis is available but there are some evidences of drug resistance, insufficient efficacy, and unpleasant side effects. In order to reach a more natural drug with suitable efficacy and the lowest side effects, the effects of the hydroalcoholic extracts of olive leaf, Satureja khuzestanica, and Allium sativum on G. lamblia cysts were evaluated in vitro, as well as antigiardial effect of the extracts was compared with metronidazole as the drug of choice...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27860303/effect-of-olive-leaf-extract-on-glucose-level-among-diabetes-induced-rats-a-systematic-review-and-meta-analysis
#6
Hamzeh Abunab, Wireen Leila Dator, Sana Hawamdeh
BACKGROUND: This systematic review statistically analyzed Randomized Controlled Trials on Olive Leaf Extract (OLE) for effectiveness in managing glucose levels in diabetic rats. METHODS: Selected articles, with no date restriction in the search process, were assessed independently by the authors using SYRCLE's risk of bias tool for animal studies. Comprehensive-Meta-analysis version 3.0 was used for data analysis. Findings from 8 trials that included 162 rats were reviewed...
November 17, 2016: Journal of Diabetes
https://www.readbyqxmd.com/read/27855900/selective-ultrasound-enhanced-enzymatic-hydrolysis-of-oleuropein-to-its-aglycon-in-olive-olea-europaea-l-leaf-extracts
#7
María Del Mar Delgado-Povedano, Feliciano Priego-Capote, María Dolores Luque de Castro
Hydrolysis of oleuropein, the main phenol in olive (Olea europaea L.) leaf extracts, to oleuropein aglycon and other subsequent products in the hydrolytic pathway can be catalyzed by different enzymes. Three of the most used hydrolases were assayed to catalyze the process, and β-glucosidase from Aspergillus niger was selected. Acceleration of the enzymatic hydrolysis by ultrasound (US) was studied using a Box-Behnken design (duty cycle, amplitude, cycle time) and an oleuropein standard, and the optimum US conditions for achieving maximum yield of oleuropein aglycon were 0...
April 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27854305/piper-sarmentosum-effects-on-11%C3%AE-hydroxysteroid-dehydrogenase-type-1-enzyme-in-serum-and-bone-in-rat-model-of-glucocorticoid-induced-osteoporosis
#8
Siti Fadziyah Mohamad Asri, Elvy Suhana Mohd Ramli, Ima Nirwana Soelaiman, Muhamad Alfakry Mat Noh, Abdul Hamid Abdul Rashid, Farihah Suhaimi
Glucocorticoid-induced osteoporosis is one of the common causes of secondary osteoporosis. Piper sarmentosum (Ps) extract possesses antioxidant and anti-inflammatory activities. In this study, we determined the correlation between the effects of Ps leaf water extract with the regulation of 11β-hydroxysteroid dehydrogenase (HSD) type 1 enzyme activity in serum and bone of glucocorticoid-induced osteoporotic rats. Twenty-four Sprague-Dawley rats were grouped into following: G1: sham-operated group administered with intramuscular vehicle olive oil and vehicle normal saline orally; G2: adrenalectomized (adrx) control group given intramuscular dexamethasone (120 μg/kg/day) and vehicle normal saline orally; G3: adrx group given intramuscular dexamethasone (120 μg/kg/day) and water extract of Piper sarmentosum (125 mg/kg/day) orally...
November 15, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27847123/leaf-biochemical-responses-and-fruit-oil-quality-parameters-in-olive-plants-subjected-to-airborne-metal-pollution
#9
Radhia Fourati, Antonio Scopa, Chedlia Ben Ahmed, Ferjani Ben Abdallah, Roberto Terzano, Concetta Eliana Gattullo, Ignazio Allegretta, Fernanda Galgano, Marisa Carmela Caruso, Adriano Sofo
This study was carried out in two olive orchards (Olea europaea L., cv. Chemlali) located in a polluted area near a fertilizers factory and in a control unpolluted site, managed with similar cultivation techniques. The aim was to investigate the physiological and biochemical responses of polluted plants (PP), exposed to atmospheric metal contamination (Cd, Cu, Fe, Mn, Ni and Pb) as compared to control plants (CP). Leaves, roots and fruits of PP showed a depression of their non-enzymatic and enzymatic antioxidant defences and a disruption of their hormonal homeostasis...
November 12, 2016: Chemosphere
https://www.readbyqxmd.com/read/27845749/unsaturated-lipids-change-in-olive-tree-drupe-and-seed-during-fruit-development-and-in-response-to-cold-stress-and-acclimation
#10
REVIEW
Simone D'Angeli, Maria Maddalena Altamura
The olive tree is a plant of economic value for the oil of its drupe. It is a cultigen complex composed of genotypes with differences in cold-hardiness. About 90% of the oil is stored in oil bodies (OBs) in the drupe during the oleogenic phase. Phenols and lipids contribute to oil quality, but the unsaturated fatty acid (FA) fraction is emerging as the most important for quality, because of the very high content in oleic acid, the presence of ω6-linoleic acid and ω3-linolenic acid, and the very low saturated FA content...
November 12, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27834936/a-novel-strain-of-tomato-leaf-curl-new-delhi-virus-has-spread-to-the-mediterranean-basin
#11
Isabel M Fortes, Sonia Sánchez-Campos, Elvira Fiallo-Olivé, Juan A Díaz-Pendón, Jesús Navas-Castillo, Enrique Moriones
Tomato leaf curl New Delhi virus (ToLCNDV) is a whitefly-transmitted bipartite begomovirus (genus Begomovirus, family Geminiviridae) that causes damage to multiple cultivated plant species mainly belonging to the Solanaceae and Cucurbitaceae families. ToLCNDV was limited to Asian countries until 2012, when it was first reported in Spain, causing severe epidemics in cucurbit crops. Here, we show that a genetically-uniform ToLCNDV population is present in Spain, compatible with a recent introduction. Analyses of ToLCNDV isolates reported from other parts of the world indicated that this virus has a highly heterogeneous population genetically with no evident geographical, plant host or year-based phylogenetic groups observed...
November 10, 2016: Viruses
https://www.readbyqxmd.com/read/27812425/a-new-species-of-brachycephalus-anura-brachycephalidae-from-santa-catarina-southern-brazil
#12
Marcos R Bornschein, Luiz F Ribeiro, David C Blackburn, Edward L Stanley, Marcio R Pie
A new species of Brachycephalus (Anura: Brachycephalidae) is described from the Atlantic Forest of northeastern state of Santa Catarina, southern Brazil. Nine specimens (eight adults and a juvenile) were collected from the leaf litter of montane forests 790-835 m above sea level (a.s.l.). The new species is a member of the pernix group by its bufoniform shape and the absence of dermal co-ossification and is distinguished from all its congeners by a combination of its general coloration (dorsal region of head, dorsum, legs, arms, and flanks light, brownish green to dark, olive green, with darker region in the middle of the dorsum and a white line along the vertebral column in most specimens) and by its smooth dorsum...
2016: PeerJ
https://www.readbyqxmd.com/read/27811077/characterization-of-a-novel-%C3%AE-barrel-protein-atom47-from-the-mitochondrial-outer-membrane-of-arabidopsis-thaliana
#13
Lu Li, Szymon Kubiszewski-Jakubiak, Jordan Radomiljac, Yan Wang, Simon R Law, Olivier Keech, Reena Narsai, Oliver Berkowitz, Owen Duncan, Monika W Murcha, James Whelan
In plant cells, mitochondria are major providers of energy and building blocks for growth and development as well as abiotic and biotic stress responses. They are encircled by two lipid membranes containing proteins that control mitochondrial function through the import of macromolecules and metabolites. Characterization of a novel β-barrel protein, OUTER MEMBRANE PROTEIN 47 (OM47), unique to the green lineage and related to the voltage-dependent anion channel (VDAC) protein family, showed that OM47 can complement a VDAC mutant in yeast...
November 2016: Journal of Experimental Botany
https://www.readbyqxmd.com/read/27793154/in-silico-metabolic-network-analysis-of-arabidopsis-leaves
#14
Veronique Beckers, Lisa Maria Dersch, Katrin Lotz, Guido Melzer, Oliver Ernst Bläsing, Regine Fuchs, Thomas Ehrhardt, Christoph Wittmann
BACKGROUND: During the last decades, we face an increasing interest in superior plants to supply growing demands for human and animal nutrition and for the developing bio-based economy. Presently, our limited understanding of their metabolism and its regulation hampers the targeted development of desired plant phenotypes. In this regard, systems biology, in particular the integration of metabolic and regulatory networks, is promising to broaden our knowledge and to further explore the biotechnological potential of plants...
October 29, 2016: BMC Systems Biology
https://www.readbyqxmd.com/read/27783958/effect-of-two-different-composts-on-soil-quality-and-on-the-growth-of-various-plant-species-in-a-polymetallic-acidic-mine-soil
#15
S Rossini-Oliva, M D Mingorance, A Peña
The effect of the addition (0-10%) of two types of sewage sludge composts (composted sewage sludge [CS] and sewage sludge co-composted with olive prune wastes [CSO]) on a polymetallic acidic soil from the Riotinto mining area was evaluated by i) a soil incubation experiment and ii) a greenhouse pot experiment using tomato (Solanum lycopersicum Mill.), ryegrass (Lolium perenne L.) and ahipa (Pachyrhizus ahipa (Wedd.) Parodi). Compost addition improved the soil organic carbon content, increased the pH and the electrical conductivity and enhanced enzyme activities and soil respiration, more for CSO than for CS...
October 23, 2016: Chemosphere
https://www.readbyqxmd.com/read/27773270/kinetic-improvement-of-olive-leaves-bioactive-compounds-extraction-by-using-power-ultrasound-in-a-wide-temperature-range
#16
Ibtihel Khemakhem, Margarita Hussam Ahmad-Qasem, Enrique Barrajón Catalán, Vicente Micol, Jose Vicente García-Pérez, Mohamed Ali Ayadi, Mohamed Bouaziz
In this study, the effect of temperature and ultrasonic application on extraction kinetics of polyphenols from dried olive leaf was investigated. Conventional (CVE) and ultrasonic-assisted extraction (UAE) were performed at 10, 20, 30, 50 and 70°C using water as solvent. Extracts were characterized by measuring the total phenolic content, the antioxidant capacity and the oleuropein content (HPLC-DAD/MS-MS). Moreover, Naik's model was used to mathematically describe the extraction kinetics. The experimental results showed that phenolic extraction was faster in UAE (ultrasonic-assisted extraction) than in CVE (conventional extraction), being extraction kinetics satisfactorily described using Naik model (include VAR>98%)...
January 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/27771503/effect-of-moderate-high-temperature-on-the-vegetative-growth-and-potassium-allocation-in-olive-plants
#17
María Benlloch-González, José Manuel Quintero, María Paz Suárez, Rosa Sánchez-Lucas, Ricardo Fernández-Escobar, Manuel Benlloch
There is little information about the prolonged effect of a moderately high temperature on the growth of olive (Olea europaea L.). It has been suggested that when the temperature of the air rises above 35°C the shoot growth of olive is inhibited while there is any reference on how growth is affected when the soil is warmed. In order to examine these effects, mist-cuttings and young plants generated from seeds were grown under moderate high temperature (37°C) for 64 and 42days respectively. In our study, plant dry matter accumulation was reduced when the temperature of both the air and the root medium was moderately high...
December 1, 2016: Journal of Plant Physiology
https://www.readbyqxmd.com/read/27768811/the-variation-of-productivity-and-its-allocation-along-a-tropical-elevation-gradient-a-whole-carbon-budget-perspective
#18
Yadvinder Malhi, Cécile A J Girardin, Gregory R Goldsmith, Christopher E Doughty, Norma Salinas, Daniel B Metcalfe, Walter Huaraca Huasco, Javier E Silva-Espejo, Jhon Del Aguilla-Pasquell, Filio Farfán Amézquita, Luiz E O C Aragão, Rossella Guerrieri, Françoise Yoko Ishida, Nur H A Bahar, William Farfan-Rios, Oliver L Phillips, Patrick Meir, Miles Silman
Why do forest productivity and biomass decline with elevation? To address this question, research to date generally has focused on correlative approaches describing changes in woody growth and biomass with elevation. We present a novel, mechanistic approach to this question by quantifying the autotrophic carbon budget in 16 forest plots along a 3300 m elevation transect in Peru. Low growth rates at high elevations appear primarily driven by low gross primary productivity (GPP), with little shift in either carbon use efficiency (CUE) or allocation of net primary productivity (NPP) between wood, fine roots and canopy...
October 21, 2016: New Phytologist
https://www.readbyqxmd.com/read/27738877/sasa-veitchii-extract-suppresses-carbon-tetrachloride-induced-hepato-and-nephrotoxicity-in-mice
#19
Hiroki Yoshioka, Miki Tanaka, Hirohisa Fujii, Tsunemasa Nonogaki
OBJECTIVE: The aim of this study was to investigate the therapeutic effects of a Sasa veitchii leaf extract (SE) on carbon tetrachloride (CCl4)-induced hepato- and nephrotoxicity. METHODS: Seven-week-old male ddy mice were orally administered SE or saline for seven days. Twenty-four hours after the last SE or saline administration, the mice were intraperitoneally injected with 3 g/kg CCl4 or olive oil. The mice from each group were euthanized and bled for plasma analysis 24 h after the CCl4/olive oil injection...
November 2016: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/27719659/cardioprotective-effects-of-the-polyphenol-hydroxytyrosol-from-olive-oil
#20
Silvia Tejada, Samuel Pinya, Maria Del Mar Bibiloni, Josep A Tur, Antoni Pons, Antoni Sureda
The Mediterranean diet includes olive oil as its primary source of fat. This diet is frequently associated to longevity and a lower incidence of chronic diseases thanks to its biological activities and health effects. Apart from oleic acid, olive oil contains many bioactive components including polyphenols that have been reported to exert antioxidant and anti-inflammatory activities. Polyphenols may for the most part be responsible for the protective effects against cardiovascular diseases associated with olive oil...
October 5, 2016: Current Drug Targets
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