keyword
MENU ▼
Read by QxMD icon Read
search

artificial muscle

keyword
https://www.readbyqxmd.com/read/29451150/identification-of-seven-novel-mutations-in-the-acid-alpha-glucosidase-gene-in-five-chinese-patients-with-late-onset-pompe-disease
#1
Hua-Xu Liu, Chuan-Qiang Pu, Qiang Shi, Yu-Tong Zhang, Rui Ban
Background: Pompe disease is a rare lysosomal glycogen storage disorder linked to the acid alpha-glucosidase gene (GAA). A wide clinical and genetic variability exists between patients from different ethnic populations, and the genotype-phenotype correlations are still not well understood. The aim of this study was to report the clinicopathological and genetic characteristics of five Chinese patients with late-onset Pompe disease (LOPD) who carried novel GAA gene mutations. Methods: Clinical and pathological data of patients diagnosed with glycogen storage disease at our institution from April 1986 to August 2017 were collected, and next-generation sequencing of frozen muscle specimens was conducted...
February 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29448867/comparison-of-the-knitted-silk-vascular-grafts-coated-with-fibroin-sponges-prepared-using-glycerin-poly-ethylene-glycol-diglycidyl-ether-and-poly-ethylene-glycol-as-porogens
#2
Takashi Tanaka, Akiko Uemura, Ryo Tanaka, Yugo Tasei, Tetsuo Asakura
Development of a small-diameter artificial vascular graft is urgent because existing materials often occlude within a short time. We have shown that small-diameter vascular graft using Bombyx mori silk fibroin is a potential candidate. Silk fibroin grafts are fabricated by coating silk fibroin on the knit tube prepared from silk fibroin fibers. However, there is a serious problem that the coated silk fibroin portion hardens when alcohol is used for insolubilization of the coated silk fibroin. This hardening prevents the desired biodegradation of the coated silk fibroin...
January 1, 2018: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/29448864/development-of-a-novel-6-dof-parallel-mechanism-moving-platform-for-investigating-the-effects-of-multimodal-sensory-feedback-information-regarding-postural-stability-in-humans
#3
Shuta Sato, Motoki Takagi, Tasuku Miyoshi
The purpose of this study was to develop a six-degree-of-freedom parallel mechanism moving platform to investigate the effects of multimodal sensory feedback information while standing upright. We constructed a custom-designed disturbance-applying instrument (DAI) consisting of a support surface suspended from eight pneumatic artificial muscles. The posture of the support surface was controlled with a proportional-integral-derivative (PID) feedback system using an infra-red camera-based real-time 3D motion capture system, and was estimated by step and frequency responses...
February 15, 2018: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/29446620/polydopamine-coated-main-chain-liquid-crystal-elastomer-as-optically-driven-artificial-muscle
#4
Hongmiao Tian, Zhijian Wang, Yilong Chen, Jinyou Shao, Tong Gao, Shengqiang Cai
Optically-driven active materials have received much attention because their deformation and motion can be controlled remotely, instantly and precisely in a contactless way. In this article, we investigated an optically-actuated elastomer with rapid response: polydopamine (PDA)-coated liquid crystal elastomer (LCE). Due to the photothermal effect of PDA coating and thermal responsiveness of LCE, the elastomer film contracted significantly with near infrared (NIR) irradiation. With a fixed strain, light-induced actuating stress in the film could be as large as 1...
February 15, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29446146/crispr-cas9-mediated-mstn-disruption-and-heritable-mutagenesis-in-goats-causes-increased-body-mass
#5
X Wang, Y Niu, J Zhou, H Zhu, B Ma, H Yu, H Yan, J Hua, X Huang, L Qu, Y Chen
Genetic engineering in livestock has been greatly enhanced through the use of artificial programmed nucleases such as the recently emerged clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (Cas9) system. We recently reported our successful application of the CRISPR/Cas9 system to engineer the goat genome through micro-injection of Cas9 mRNA and sgRNAs targeting MSTN and FGF5 in goat embryos. The phenotypes induced by edited loss-of-function mutations of MSTN remain to be evaluated extensively...
February 2018: Animal Genetics
https://www.readbyqxmd.com/read/29440680/an-allogeneic-off-the-shelf-therapeutic-strategy-for-peripheral-nerve-tissue-engineering-using-clinical-grade-human-neural-stem-cells
#6
C O'Rourke, A G E Day, C Murray-Dunning, L Thanabalasundaram, J Cowan, L Stevanato, N Grace, G Cameron, R A L Drake, J Sinden, J B Phillips
Artificial tissues constructed from therapeutic cells offer a promising approach for improving the treatment of severe peripheral nerve injuries. In this study the effectiveness of using CTX0E03, a conditionally immortalised human neural stem cell line, as a source of allogeneic cells for constructing living artificial nerve repair tissue was tested. CTX0E03 cells were differentiated then combined with collagen to form engineered neural tissue (EngNT-CTX), stable aligned sheets of cellular hydrogel. EngNT-CTX sheets were delivered within collagen tubes to repair a 12 mm sciatic nerve injury model in athymic nude rats...
February 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29438104/programmable-and-functional-electrothermal-bimorph-actuators-based-on-large-area-anisotropic-carbon-nanotube-paper
#7
Qingwei Li, Changhong Liu, Shoushan Fan
The electro-active polymer (EAP) actuators, such as electronic, ionic and electrothermal (ET) actuators, have become the important branch of next-generation soft actuators in bionic robotics. However, most reported EAP actuators could only realize simple movements which are restricted by the small area of flexible electrodes and simple designs. Herein, we prepared large-area flexible electrodes with high anisotropy made of oriented carbon nanotube (CNT) paper, and carried out artful graphic designs and processing on the electrodes to make functional ET bimorph actuators which can realize large bending deformations (over 220°, curvature > 1...
February 13, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29435856/modern-theories-of-pelvic-floor-support-a-topical-review-of-modern-studies-on-structural-and-functional-pelvic-floor-support-from-medical-imaging-computational-modeling-and-electromyographic-perspectives
#8
REVIEW
Yun Peng, Brandi D Miller, Timothy B Boone, Yingchun Zhang
PURPOSE OF REVIEW: Weakened pelvic floor support is believed to be the main cause of various pelvic floor disorders. Modern theories of pelvic floor support stress on the structural and functional integrity of multiple structures and their interplay to maintain normal pelvic floor functions. Connective tissues provide passive pelvic floor support while pelvic floor muscles provide active support through voluntary contraction. Advanced modern medical technologies allow us to comprehensively and thoroughly evaluate the interaction of supporting structures and assess both active and passive support functions...
February 12, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29424673/nerve-fascicle-transfer-using-a-part-of-the-c-7-nerve-for-spinal-accessory-nerve-injury
#9
Xuan Ye, Yun-Dong Shen, Jun-Tao Feng, Wen-Dong Xu
OBJECTIVE Spinal accessory nerve (SAN) injury results in a series of shoulder dysfunctions and continuous pain. However, current treatments are limited by the lack of donor nerves as well as by undesirable nerve regeneration. Here, the authors report a modified nerve transfer technique in which they employ a nerve fascicle from the posterior division (PD) of the ipsilateral C-7 nerve to repair SAN injury. The technique, first performed in cadavers, was then undertaken in 2 patients. METHODS Six fresh cadavers (12 sides of the SAN and ipsilateral C-7) were studied to observe the anatomical relationship between the SAN and C-7 nerve...
February 9, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29424012/true-low-power-self-locking-soft-actuators
#10
Seung Jae Kim, Onnuri Kim, Moon Jeong Park
Natural double-layered structures observed in living organisms are known to exhibit asymmetric volume changes with environmental triggers. Typical examples are natural roots of plants, which show unique self-organized bending behavior in response to environmental stimuli. Herein, light- and electro-active polymer (LEAP) based actuators with a double-layered structure are reported. The LEAP actuators exhibit an improvement of 250% in displacement and hold an object three times heavier as compared to that in the case of conventional electro-active polymer actuators...
February 9, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29414537/an-optimal-control-strategy-for-hybrid-actuator-systems-application-to-an-artificial-muscle-with-electric-motor-assist
#11
Koji Ishihara, Jun Morimoto
Humans use multiple muscles to generate such joint movements as an elbow motion. With multiple lightweight and compliant actuators, joint movements can also be efficiently generated. Similarly, robots can use multiple actuators to efficiently generate a one degree of freedom movement. For this movement, the desired joint torque must be properly distributed to each actuator. One approach to cope with this torque distribution problem is an optimal control method. However, solving the optimal control problem at each control time step has not been deemed a practical approach due to its large computational burden...
January 11, 2018: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/29414479/modelling-a-soft-composite-accumulator-for-human-mobility-assist-devices
#12
Robert Shaheen, Marc Doumit
Research in the field of human mobility assist devices, aiming to reduce the metabolic cost of daily activities, is seeing the benefits of the exclusive use of accumulators to store and release energy during the gait cycle. The Pneumatic Artificial Muscle, used in a passive state, has proven to be a superior choice for these devices when compared to its alternatives, however, challenges regarding muscle pressure dissipation and a limited elongation potential have been identified. A recently developed, novel Soft Composite material has been shown to experimentally replicate the distinctive mechanical behaviour of the Pneumatic Artificial Muscle, without the need for internal pressurization...
January 31, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29412084/fiber-reinforced-origamic-robotic-actuator
#13
Juan Yi, Xiaojiao Chen, Chaoyang Song, Zheng Wang
A novel pneumatic soft linear actuator Fiber-reinforced Origamic Robotic Actuator (FORA) is proposed with significant improvements on the popular McKibben-type actuators, offering nearly doubled motion range, substantially improved force profile, and significantly lower actuation pressure. The desirable feature set is made possible by a novel soft origamic chamber that expands radially while contracts axially when pressurized. Combining this new origamic chamber with a reinforcing fiber mesh, FORA generates very high traction force (over 150N) and very large contractile motion (over 50%) at very low input pressure (100 kPa)...
February 2018: Soft Robotics
https://www.readbyqxmd.com/read/29408646/utrophin-up-regulation-by-artificial-transcription-factors-induces-muscle-rescue-and-impacts-the-neuromuscular-junction-in-mdx-mice
#14
Cinzia Pisani, Georgios Strimpakos, Francesca Gabanella, Maria Grazia Di Certo, Annalisa Onori, Cinzia Severini, Siro Luvisetto, Stefano Farioli-Vecchioli, Irene Carrozzo, Antonio Esposito, Tamara Canu, Elisabetta Mattei, Nicoletta Corbi, Claudio Passananti
Up-regulation of the dystrophin-related gene utrophin represents a promising therapeutic strategy for the treatment of Duchenne Muscular Dystrophy (DMD). In order to re-program the utrophin expression level in muscle, we engineered artificial zinc finger transcription factors (ZF-ATFs) that target the utrophin "A" promoter. We have previously shown that the ZF-ATF "Jazz", either by transgenic manipulation or by systemic adeno-associated viral delivery, induces significant rescue of muscle function in dystrophic "mdx" mice...
January 30, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29399894/soft-ultrathin-electronics-innervated-adaptive-fully-soft-robots
#15
Chengjun Wang, Kyoseung Sim, Jin Chen, Hojin Kim, Zhoulyu Rao, Yuhang Li, Weiqiu Chen, Jizhou Song, Rafael Verduzco, Cunjiang Yu
Soft robots outperform the conventional hard robots on significantly enhanced safety, adaptability, and complex motions. The development of fully soft robots, especially fully from smart soft materials to mimic soft animals, is still nascent. In addition, to date, existing soft robots cannot adapt themselves to the surrounding environment, i.e., sensing and adaptive motion or response, like animals. Here, compliant ultrathin sensing and actuating electronics innervated fully soft robots that can sense the environment and perform soft bodied crawling adaptively, mimicking an inchworm, are reported...
February 5, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29382028/intraoperative-conversion-of-artificial-cervical-disc-replacement-to-anterior-cervical-discectomy-and-fusion-for-iatrogenic-fracture-a-rare-case-report
#16
Bei-Yu Wang, Ting-Kui Wu, Hao Liu, Yu-Xiao Deng, Chen Ding
RATIONALE: Artificial cervical disc replacement (ACDR) has been reported to be an effective and safe surgical treatment for cervical spondylosis. However, iatrogenic fracture during ACDR surgery has rarely been reported. Considering its infrequency, we report a rare clinical case, with the aim of sharing our experience and exploring when to convert ACDR to fusion intraoperatively. PATIENTS CONCERNS: A 47-year-old woman felt neck pain with weakness and numbness in both upper limbs for 5 months...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29380001/joint-preserving-treatment-options-for-irreparable-rotator-cuff-tears
#17
REVIEW
P Valenti
An irreparable cuff tear is defined as the inability to achieve direct repair of native tendon to the great tuberosity despite intra- and extra-articular release of the remaining tissue. Three distinct anatomic patterns are identified: posterosuperior cuff tears which involve the supraspinatus, infraspinatus and teres minor; anterosuperior tears which involve the supraspinatus and subscapularis; and global tears which comprise both. Subacromial debridement and tenotomy or tenodesis of the long head of the biceps are proposed for older patients with a functional but very painful shoulder...
January 29, 2018: Der Orthopäde
https://www.readbyqxmd.com/read/29379672/series-pneumatic-artificial-muscles-spams-and-application-to-a-soft-continuum-robot
#18
Joseph D Greer, Tania K Morimoto, Allison M Okamura, Elliot W Hawkes
We describe a new series pneumatic artificial muscle (sPAM) and its application as an actuator for a soft continuum robot. The robot consists of three sPAMs arranged radially round a tubular pneumatic backbone. Analogous to tendons, the sPAMs exert a tension force on the robot's pneumatic backbone, causing bending that is approximately constant curvature. Unlike a traditional tendon driven continuum robot, the robot is entirely soft and contains no hard components, making it safer for human interaction. Models of both the sPAM and soft continuum robot kinematics are presented and experimentally verified...
May 2017: IEEE International Conference on Robotics and Automation: ICRA: [proceedings]
https://www.readbyqxmd.com/read/29378445/real-time-closed-loop-functional-electrical-stimulation-control-of-muscle-activation-with-evoked-electromyography-feedback-for-spinal-cord-injured-patients
#19
Zhan Li, David Guiraud, David Andreu, Anthony Gelis, Charles Fattal, Mitsuhiro Hayashibe
Functional electrical stimulation (FES) is a neuroprosthetic technique to help restore motor function of spinal cord-injured (SCI) patients. Through delivery of electrical pulses to muscles of motor-impaired subjects, FES is able to artificially induce their muscle contractions. Evoked electromyography (eEMG) is used to record such FES-induced electrical muscle activity and presents a form of [Formula: see text]-wave. In order to monitor electrical muscle activity under stimulation and ensure safe stimulation configurations, closed-loop FES control with eEMG feedback is needed to be developed for SCI patients who lose their voluntary muscle contraction ability...
December 25, 2017: International Journal of Neural Systems
https://www.readbyqxmd.com/read/29363212/photoredox-based-actuation-of-an-artificial-molecular-muscle
#20
Kevin P Liles, Angelique F Greene, Mary K Danielson, Nathan D Colley, Andrew Wellen, Jeremy M Fisher, Jonathan C Barnes
The use of light to actuate materials is advantageous because it represents a cost-effective and operationally straightforward way to introduce energy into a stimuli-responsive system. Common strategies for photoinduced actuation of materials typically rely on light irradiation to isomerize azobenzene or spiropyran derivatives, or to induce unidirectional rotation of molecular motors incorporated into a 3D polymer network. Although interest in photoredox catalysis has risen exponentially in the past decade, there are far fewer examples where photoinduced electron transfer (PET) processes are employed to actuate materials...
January 24, 2018: Macromolecular Rapid Communications
keyword
keyword
114905
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"