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https://www.readbyqxmd.com/read/28820557/papillary-muscle-rupture-in-an-adolescent-with-no-coronary-lesions
#1
Tatjana Lejko Zupanc, Mateja Logar
A 21-year-old man with Wolff-Parkinson-White syndrome presented to the authors' hospital with ventricular fibrillation. Coronary angiography failed to demonstrate coronary stenosis, but temporary mechanical circulatory support resolved the ventricular fibrillation and the patient was extubated eight days later. On the next day, however, he had to be re-intubated with symptoms of congestive heart failure. Echocardiography revealed new severe mitral regurgitation and a mobile mass, while emergency surgery revealed a posteromedial papillary muscle rupture (PMR)...
March 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28819228/convergent-and-divergent-genetic-changes-in-the-genome-of-chinese-and-european-pigs
#2
Jing Wang, Huiying Zou, Lei Chen, Xi Long, Jing Lan, Wenjie Liu, Li Ma, Chao Wang, Xinyu Xu, Liming Ren, Zhenglong Gu, Ning Li, Xiaoxiang Hu, Yaofeng Zhao, Yiqiang Zhao
Since 10,000 BC, continuous human selection has led to intense genetic and phenotypic changes in pig (Sus scrofa) domestication. Through whole genome analysis of 257 individuals, we demonstrated artificial unidirectional and bidirectional selection as the primary force to shape the convergent and divergent changes between Chinese domestic pigs (CHD) and European domestic pigs (EUD). We identified 31 genes in unidirectional selection regions that might be related to fundamental domestication requirements in pigs...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28818139/bed-rest-and-intermittent-centrifugation-effects-on-human-balance-and-neuromotor-reflexes
#3
William H Paloski, Millard F Reschke, Alan H Feiveson
INTRODUCTION: The effects of repeated centrifugation in association with head-down tilt (HDT) bed rest (BR) on the mediation of basic reflexes associated with the major postural muscles was investigated as a potential countermeasure for maintaining balance control and neuromotor reflex function. METHODS: There were 15 male volunteers who were exposed to 21 d of 6° HDT-BR. Eight were treated with daily 1-h artificial gravity (AG) exposures aboard a short radius centrifuge that provided 1-g footward loading at heart level...
September 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28813941/inverse-estimation-of-multiple-muscle-activations-based-on-linear-logistic-regression
#4
Masashi Sekiya, Toshiaki Tsuji
This study deals with a technology to estimate the muscle activity from the movement data using a statistical model. A linear regression (LR) model and artificial neural networks (ANN) have been known as statistical models for such use. Although ANN has a high estimation capability, it is often in the clinical application that the lack of data amount leads to performance deterioration. On the other hand, the LR model has a limitation in generalization performance. We therefore propose a muscle activity estimation method to improve the generalization performance through the use of linear logistic regression model...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28812040/effect-of-changes-in-artificial-turf-on-sports-injuries-in-male-university-soccer-players
#5
Kohei Fujitaka, Akira Taniguchi, Tsukasa Kumai, Shingo Otuki, Mamoru Okubo, Yasuhito Tanaka
BACKGROUND: Studies comparing the types and severity of trauma and injuries caused by different types of field surfaces have been conducted. However, there have been no studies on sports injuries caused by temporal deterioration of long-pile artificial turf fields and related decreases in the rubber chip and silica sand infill. PURPOSE: To investigate the influence of an artificial turf field on sports injuries in a university soccer team. STUDY DESIGN: Descriptive epidemiological study...
August 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28807305/evaluation-of-the-priocheck%C3%A2-trichinella-aad-kit-for-the-digestion-and-recovery-of-larvae-in-pork-horse-meat-and-wild-meat
#6
Kelly Konecsni, Cheryl Scheller, Brad Scandrett, Patrik Buholzer, Alvin Gajadhar
The artificial digestion magnetic stirrer method using pepsin protease and hydrochloric acid is the standard assay for the detection of Trichinella larvae in muscle of infected animals. Recently, an alternative enzyme, serine protease, was employed in the development of a commercially available digestion kit (PrioCHECK™ Trichinella AAD Kit). This assay requires a higher digestion temperature of 60°C which kills the larvae during the digestion process, mitigating the risk of environmental contamination from the parasite...
August 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28802989/do-polyethylene-microplastic-beads-alter-the-intestinal-uptake-of-ag-in-rainbow-trout-oncorhynchus-mykiss-analysis-of-the-mp-vector-effect-using-in%C3%A2-vitro-gut-sacs
#7
Farhan R Khan, David Boyle, Elisabeth Chang, Nicolas R Bury
Microplastic (MP) vector effects have been well described in the literature but surprisingly little is in known about the impact of MPs on the intestinal uptake of contaminants. The present study aimed to determine whether the intestinal fate of Ag was affected by the presence of polyethylene MP beads. Ag (added as (110m)Ag) was introduced into the lumen of rainbow trout (Oncorhynchus mykiss) anterior/mid-intestine gut sac preparations as Ag only, Ag and MPs (co-exposure) and Ag-incubated MPs (where Ag was adsorbed to the MP)...
August 9, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28799692/logic-gate-functions-in-chemomechanical-materials
#8
REVIEW
Hans-Jörg Schneider
Chemomechanical polymers that change their shape or volume on stimulation by multiple external chemical signals, particularly on the basis of selective molecular recognition, are discussed. Several examples illustrate how such materials, usually in the form of hydrogels, can be used for the design of chemically triggered valves or artificial muscles and applied, for example, in self-healing materials or drug delivery. The most attractive feature of such materials is that they can combine sensor and actuator within single units, from nano- to macrosize...
August 11, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28798960/sequence-encoded-colloidal-origami-and-microbot-assemblies-from-patchy-magnetic-cubes
#9
Koohee Han, C Wyatt Shields, Nidhi M Diwakar, Bhuvnesh Bharti, Gabriel P López, Orlin D Velev
Colloidal-scale assemblies that reconfigure on demand may serve as the next generation of soft "microbots," artificial muscles, and other biomimetic devices. This requires the precise arrangement of particles into structures that are preprogrammed to reversibly change shape when actuated by external fields. The design and making of colloidal-scale assemblies with encoded directional particle-particle interactions remain a major challenge. We show how assemblies of metallodielectric patchy microcubes can be engineered to store energy through magnetic polarization and release it on demand by microscale reconfiguration...
August 2017: Science Advances
https://www.readbyqxmd.com/read/28771840/influence-of-l-carnitine-and-l-arginine-on-protein-synthesis-and-maturation-of-the-semitendinosus-muscle-of-lightweight-piglets
#10
J G Madsen, E Seoni, M Kreuzer, P Silacci, G Bee
Lightweight (LW) piglets from large litters display impaired growth performance compared with heavier littermates. This study investigated the growth performance and muscle development of early-weaned LW piglets (birthweight <1.2 kg) from large litters (17.3 ± 3.0 total born per litter), fed ad libitum a milk replacer supplemented with either l-carnitine (CAR) or l-arginine (ARG) from day 7 to day 28 of age. In total, 36 female and entire male Swiss Large White piglets, weaned on day 7 of age, were artificially reared in pairs in rescue decks...
August 3, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28765227/determination-of-an-optimal-pharmacokinetic-model-of-18-f-fet-for-quantitative-applications-in-rat-brain-tumors
#11
Marie Anne Richard, Jérémie P Fouquet, Réjean Lebel, Martin Lepage
O-(2-(18)F-fluoroethyl)-l-tyrosine ((18)F-FET) is a radiolabeled artificial amino acid used in PET for tumor delineation and grading. The present study compares different kinetic models to determine which are more appropriate for (18)F-FET in rats. Methods: Rats were implanted with F98 glioblastoma cells in the right hemisphere and scanned 9-15 d later. PET data were acquired during 50 min after a 1-min bolus of (18)F-FET. Arterial blood samples were drawn for arterial input function determination. Two compartmental pharmacokinetic models were tested: the 2-tissue model and the 1-tissue model...
August 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28756283/design-and-characterization-of-a-hyperelastic-tubular-soft-composite
#12
Robert Shaheen, Marc Doumit, Alexander Helal
Research in the field of human mobility assistive devices, aiming to reduce the metabolic cost of daily activities, is seeing the benefits of the exclusive use of passive actuators to store and release energy during the gait cycle. Current devices commonly employ either mechanical springs or Pneumatic Artificial Muscles as the primary method of passive actuation. The Pneumatic Artificial Muscle has proven to be a superior actuation choice for these devices, when compared to its alternatives. However, challenges regarding muscle pressure loss and limited elongation potential have been identified...
July 22, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28747938/computed-tomography-angiography-for-imaging-results-of-neochordal-mitral-valve-repair
#13
Radosław Zwoliński, Anna Marcinkiewicz, Konrad Szymczyk, Jarosław Drożdż, Ryszard Jaszewski, Bogdan Jegier
INTRODUCTION: Degenerative mitral regurgitation is currently the most frequent indication for mitral valve repair. AIM: To visualize and assess the mid-term results of mitral valve repair with neochordae implantation, using computed tomography angiography (CTA) imaging. MATERIAL AND METHODS: The CTA with ECG gating and without modulation was applied in 10 patients to assess the results of a mitral valve sparing procedure. The results of 3 patients are presented...
June 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28745624/cardiac-muscle-cell-based-actuator-and-self-stabilizing-biorobot-part-1
#14
Merrel T Holley, Neerajha Nagarajan, Christian Danielson, Pinar Zorlutuna, Kidong Park
Biological machines often referred to as biorobots, are living cell- or tissue-based devices that are powered solely by the contractile activity of living components. Due to their inherent advantages, biorobots are gaining interest as alternatives to traditional fully artificial robots. Various studies have focused on harnessing the power of biological actuators, but only recently studies have quantitatively characterized the performance of biorobots and studied their geometry to enhance functionality and efficiency...
July 11, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28739721/a-preclinical-study-of-cell-seeded-tubularized-scaffolds-specially-secreting-ll37-for-reconstruction-of-long-urethral-defects
#15
Yongwei Li, Jitao Wu, Fan Feng, Changping Men, Diandong Yang, Zhenli Gao, Zhe Zhu, Yuanshan Cui, Hongwei Zhao
AIM: We constructed a new artificial, long tubular acellular matrix, seeded with autologous progenitor cells transfected with the sequence to produce the antibiotic peptide LL37 and another two common seeding cells, which might be adopted for patients requiring repair of long segment of the urethra. MATERIALS AND METHODS: Autologous endothelial progenitor cells transfected by lentiviral vectors expressing antibiotic peptide LL37, as well as urothelial and smooth muscle cells from New Zealand white male rabbits, were cultured and seeded onto preconfigured acellular collagen-based tubular matrices (3 cm in length)...
August 2017: Anticancer Research
https://www.readbyqxmd.com/read/28737931/semiordered-hierarchical-metallic-network-for-fast-and-large-charge-induced-strain
#16
Chuan Cheng, Lukas Lührs, Tobias Krekeler, Martin Ritter, Jörg Weissmüller
Nanoporous metallic actuators for artificial muscle applications are distinguished by combining the low operating voltage, which is otherwise reserved for polymer-based actuators with interesting values of strain amplitude, strength, and stiffness that are comparable of those of piezoceramics. We report a nanoporous metal actuator with enhanced strain amplitude and accelerated switching. Our 3D macroscopic metallic muscle has semiordered and hierarchical nanoporous structure, in which μm-sized tubes align perpendicular with the sample surface, while nm-sized ligaments consist of the tube walls...
July 27, 2017: Nano Letters
https://www.readbyqxmd.com/read/28736125/minimally-invasive-treatment-of-displaced-femoral-shaft-fractures-with-a-teleoperated-robot-assisted-surgical-system
#17
Qing Zhu, Bin Liang, Xingsong Wang, Xiaogang Sun, Liming Wang
BACKGROUND: Minimally invasive surgical operation of intramedullary (IM) nailing is a standard technique for treating diaphyseal fractures. However, in addition to its advantages, there are some drawbacks such as the frequent occurrence of malalignment, physical fatigue and high radiation exposure to medical staff. The use of robotic and navigation techniques is promising treatments for femoral fractures. MATERIALS AND METHODS: This paper presents a novel robot-assisted manipulator for femoral shaft fracture reduction with indirect contact with the femur...
July 12, 2017: Injury
https://www.readbyqxmd.com/read/28732896/a-hydrogel-actuator-with-flexible-folding-deformation-and-shape-programming-via-using-sodium-carboxymethyl-cellulose-and-acrylic-acid
#18
Shuiping Wu, Feng Yu, Hua Dong, Xiaodong Cao
Hydrogel actuator is an intelligent material, which can work as artificial muscle. However, most present hydrogel actuators, due to the inferior mechanical property and uncontrolled folding property, have always resulted in slipping off or the failure of grasping an object with specific shape and required weight. In order to solve this problem, here a tough hydrogel actuator with programmable folding deformation has been prepared by combining the "selective implanting method" and "ionic coordination". The shape and folding angle (from 0 to 180 (o)) of hydrogel actuator can be precisely controlled by altering the location and size of the implanting parts that seems like the joints of finger...
October 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28732231/kernel-dynamic-policy-programming-applicable-reinforcement-learning-to-robot-systems-with-high-dimensional-states
#19
Yunduan Cui, Takamitsu Matsubara, Kenji Sugimoto
We propose a new value function approach for model-free reinforcement learning in Markov decision processes involving high dimensional states that addresses the issues of brittleness and intractable computational complexity, therefore rendering the value function approach based reinforcement learning algorithms applicable to high dimensional systems. Our new algorithm, Kernel Dynamic Policy Programming (KDPP) smoothly updates the value function in accordance to the Kullback-Leibler divergence between current and updated policies...
June 29, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/28728303/-enhancing-soft-tissue-reattachment-with-artificial-mesh-in-joint-endoprosthetic-reconstruction-for-bone-tumors
#20
J S Lin, R Chen, W Yan, D D Chen
Objective: To investigate the operative method and clinical application of the BARD(®) Mesh in enhancing joint stability and function of endoprosthetic reconstruction for bone tumors. Methods: From Jan 2013 to Jun 2015, the clinical data of 51 patients aged (44.75±23.18) years underwent wide resection of tumor and endoprosthetic reconstruction using the BARD(®) Mesh were collected. Among them, 27 were male and 24 were female. The surgical treatments received by these patients included 5 shoulder arthroplasties, 12 elbow replacements, 12 hip replacements and 32 knee replacements (including 24 femoral tumors and 8 tibial tumors)...
July 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
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