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Erectile dysfunction and diabetes

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https://www.readbyqxmd.com/read/29037887/depression-and-related-risk-factors-among-patients-with-type-2-diabetes-mellitus-jazan-area-ksa-a-cross-sectional-study
#1
Osama B Albasheer, Mohammed S Mahfouz, Yahia Solan, Duaa A Khan, Mohammed A Muqri, Haneen A Almutairi, Ali M Alelyani, Hussain A Alahmed
PURPOSE: To determine the prevalence of depression and related risk factors among type 2 diabetes mellitus patients (T2DM) in Jazan area, Saudi Arabia. METHOD: A cross sectional, self-administered questionnaire study was conducted among T2DM patients in Jazan area, Saudi Arabia. A total of 385 patients were selected at randomly. The Patient Health Questionnaire (PHQ-9) was utilized to measure symptoms and signs of depression. RESULTS: The overall prevalence of depression among T2DM patients was 37...
September 28, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29021708/effects-of-ginseng-on-stress-related-depression-anxiety-and-the-hypothalamic-pituitary-adrenal-axis
#2
REVIEW
Seungyeop Lee, Dong-Kwon Rhee
Ginseng effectively regulates the immune response and the hormonal changes due to stress, thus maintaining homeostasis. In addition to suppressing the occurrence of psychological diseases such as anxiety and depression, ginseng also prevents stress-associated physiological diseases. Recent findings have revealed that ginseng is involved in adjusting the hypothalamic-pituitary-adrenal axis and controlling hormones, thus producing beneficial effects on the heart and brain, and in cases of bone diseases, as well as alleviating erectile dysfunction...
October 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28993149/relationship-of-blood-pressure-and-erectile-dysfunction-in-men-without-previously-diagnosed-hypertension
#3
Arto Heikkilä, Antti Kaipia, Maarit Venermo, Hannu Kautiainen, Päivi Korhonen
BACKGROUND: Erectile dysfunction (ED) is the most common male sexual disorder that affects all age groups and has a close association with essential hypertension. AIM: To characterize the relation of blood pressure and ED in detail. METHODS: A cross-sectional population-based study of 45- to 70-year-old men without previously diagnosed hypertension, cardiovascular diseases, renal disease, or diabetes was conducted from 2005 to 2007 in southwestern Finland...
October 6, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28952694/-transperineal-ultrasound-imaging-of-the-internal-pudendal-artery-in-arteriogenic-erectile-dysfunction
#4
E Povelitsa, N I Dosta, O V Parhomenko, D M Nitkin, A M Shesternja, V V Anichkin
AIM: To determine the practical and diagnostic value of transperineal ultrasound imaging of the internal pudendal artery (IPA) in patients with arteriogenic erectile dysfunction (ED). MATERIALS AND METHODS: Transperineal IPA and penile Doppler ultrasonography was performed in 50 healthy young male volunteers aged 23.6+/-3.4 years without ED (IIEF-5 score of 21-22) and 60 patients with ED (IIEF-5 score of 6-18, mean age 49+/-4.6 years), including 30 men with prostate cancer (PCa) after comprehensive treatment and 30 patients with type 1 and type 2 diabetes mellitus...
September 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28944704/the-relationship-between-vitamin-d-level-and-erectile-dysfunction-in-patients-with-type-2-diabetes-mellitus
#5
Sema Basat, Rıdvan Sivritepe, Damla Ortaboz, Ecem Sevim Çalık, Eyüp Veli Küçük, Berkan Şimşek, Sabri Atay, Arzu Çalışgan
Recent studies have suggested that a relationship could exist between 25-hydroxyvitamin D [25(OH)D] deficiency and erectile dysfunction (ED). The present study evaluated the relationship between 25(OH)D levels and ED in male patients with type 2 diabetes mellitus (DM). The study included 98 patients with type 2 DM aged between 18-80 years. The International Index of Erectile Function (IIEF-5) Questionnaire was administered. The patients were divided into three groups according to IIEF-5 scoring: IIEF-5 score between 5-10, severe ED; IIEF-5 score between 11-20, moderate ED; IIEF-5 score between 21-25, no ED...
September 23, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28926936/relationships-of-sexual-dysfunction-with-depression-and-acceptance-of-illness-in-women-and-men-with-type-2-diabetes-mellitus
#6
Ewelina Bąk, Czeslaw Marcisz, Sylwia Krzemińska, Dorota Dobrzyn-Matusiak, Agnieszka Foltyn, Agnieszka Drosdzol-Cop
An increased prevalence of sexual disorders has been reported in patients with type 2 diabetes. The aim of this study is the assessment of the influence of the psychical condition, the concentration of glycated hemoglobin, the duration of diabetes, the body mass index, the age, and the subjective acceptance of the illness on sexual disorders occurring in women and men with type 2 diabetes. The study enrolled 215 patients (114 women and 101 men) with type 2 diabetes and 183 controls. Sexuality was determined in all of the studied subjects using: the Female Sexual Function Index (FSFI) in women and the International Index of Erectile Function (IIEF) in men...
September 16, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28923309/altered-penile-caveolin-expression-in-diabetes-potential-role-in-erectile-dysfunction
#7
Jay Parikh, Alice Zemljic-Harpf, Johnny Fu, Dimosthenis Giamouridis, Tung-Chin Hsieh, Adam Kassan, Karnam S Murthy, Valmik Bhargava, Hemal H Patel, M Raj Rajasekaran
BACKGROUND: The pathophysiology of increased severity of erectile dysfunction in men with diabetes and their poor response to oral pharmacotherapy are unclear. Defective vascular endothelium and consequent impairment in the formation and action of nitric oxide (NO) are implicated as potential mechanisms. Endothelial NO synthase, critical for NO generation, is localized to caveolae, plasma membrane lipid rafts enriched in structural proteins, and caveolins. Type 2 diabetes mellitus (T2DM)-induced changes in caveolin expression are recognized to play a role in cardiovascular dysfunction...
October 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28911977/screening-for-sexual-dissatisfaction-among-people-with-type-2-diabetes-in-primary-care
#8
Anne Bijlsma-Rutte, Annemarie M J Braamse, Patricia van Oppen, Frank J Snoek, Paul Enzlin, Peter Leusink, Giel Nijpels, Petra J M Elders
AIMS: The identification and discussion of sexual care needs in people with type 2 diabetes mellitus (T2DM) in primary care is currently insufficient. The objective of this study was to determine the prevalence of sexual dissatisfaction, sexual problems and need for help by using a screening instrument among people with T2DM in primary care. METHODS: Data were collected in 45 general practices in the Netherlands from January 2015 to February 2016. The Brief Sexual Symptom Checklist (BSSC) was used to screen among 40-75 year old men and women...
August 4, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28894631/ethnopharmacological-survey-on-traditional-medicinal-plants-at-kalaroa-upazila-satkhira-district-khulna-division-bangladesh
#9
Oby Dulla, Farhana Israt Jahan
AIM: The traditional source of medicinal plants is an important way for daily curative uses in the rural area throughout Bangladesh. An ethnomedicinal survey was conducted in a randomized manner among traditional medicinal practitioners to find out about the medicinal plants of Kalaroa, Bangladesh. MATERIALS AND METHODS: The information was collected through conducting interviews, discussion, and field observations with herbal healers and knowledgeable elders of the study areas from November 01, 2015, to December 31, 2015, who pointed out various medicinal plants and described their uses, using semi-structured questionnaires...
July 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28874333/prevalence-and-risk-factors-for-erectile-dysfunction-in-chinese-adult-males
#10
Xinyu Zhang, Bin Yang, Ni Li, Hongjun Li
BACKGROUND: There is a lack of nationwide epidemiologic survey data on the prevalence estimate of erectile dysfunction (ED) in Chinese men living on the mainland China. AIM: To attain the representative prevalence estimate of ED in the Chinese male population and to analyze potential risk factors associated with ED by demographics, socioeconomic status, and medical comorbidities. METHODS: The study was community based. The five-item Internation Index of Erectile Function questionnaire and in-person interview were used to obtain data...
October 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28861293/erectile-dysfunction-in-the-elderly-male
#11
REVIEW
Mehmet İlker Gökçe, Önder Yaman
Erectile dysfunction (ED) is a health problem which mainly effects elderly men and this problem has become a more important health problem with the increased life expectancy. The basic risk factors of ED are hypertension, dyslipidemia, diabetes mellitus, and atherosclerotic heart disease which also have a higher incidence in the elderly men. The aim of this review article is to highlight the age-related changes in ED together with recommendations for patient evaluation and treatment.
September 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28831925/diabetes-mellitus-and-male-aging-pharmacotherapeutics-and-clinical-implications
#12
Swathi Putta, Ilaria Peluso, Nagendra Sastry Yarla, Eswar Kumar Kilari, Anupam Bishayee, Da-Yong Lu, George E Barreto, Ghulam Md Ashraf, Luciana Scotti, Marcus T Scotti, Rajeev K Singla, Thonos Alexiou, Atanas G Atanasov, Vadim V Tarasov, P Veera Bramhachari, Sarat Babu Imandi, Madhuri Chintala, Bechan Sharma, Marcella Reale, Rosanna Filosa, Gjumrakch Aliev, Mohammad Amjad Kamal
Andropause or male menopause is defined as androgen decline and onset of hypogonadism in the aging male. Testosterone deficiency in adult male is associated with diabetes mellitus, coronary artery disease, and heart failure. Type 2 diabetic male patients aged above 30 years showed low testosterone levels which is common in diabetic men and had symptoms of hypogonadism. Male sexual dysfunction among diabetic patients can include disorders of libido, ejaculatory problems, and erectile dysfunctions are common among people with diabetes, particularly in older men who had diabetes for years...
August 22, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28828353/impact-of-poor-glycemic-control-of-type-2-diabetes-mellitus-on-serum-prostate-specific-antigen-concentrations-in-men
#13
Hasan Anıl Atalay, Murat Akarsu, Lutfi Canat, Volkan Ülker, İlter Alkan, Unsal Ozkuvancı
BACKGROUND: To evaluate the impact of poor glycemic control of type 2 diabetes mellitus (T2DM) on serum prostate-specific antigen (PSA) concentrations in men. METHODS: We performed a prospective analysis of 215 consecutive patients affected by erectile dysfunction (ED). ED was evaluated using the IIEF-5 questionnaire and the poor glycemic control (PGC) of T2DM was assessed according to the HbA1c criteria (International Diabetes Federation). Patients were divided into PGC group (HbA1c ≥ 7%) and control group (CG) (HbA1c < 6%)...
September 2017: Prostate International
https://www.readbyqxmd.com/read/28827086/risk-factors-for-erectile-dysfunction-in-men-with-htlv-1
#14
Cassius José Vitor de Oliveira, José Abraão Carneiro Neto, Rosana C P Andrade, Paulo Novis Rocha, Edgar Marcelino de Carvalho Filho
BACKGROUND: Erectile dysfunction (ED) occurs in more than 50% of patients with human T-cell lymphotropic virus type 1 (HTLV-1) infection. In the general population, atherosclerosis is the main risk factor related to ED. AIM: To compare the contribution of neurologic disorders from HTLV-1 with that of atherosclerosis as risk factors for ED in men with HTLV-1. METHODS: In this cross-sectional study, men 18 to 70 years old with HTLV-1 were classified into one of two groups according to the presence or absence of ED...
October 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28805967/prognostic-value-of-exercise-capacity-among-men-undergoing-pharmacologic-treatment-for-erectile-dysfunction-the-fit-project
#15
Robert V Same, Mahmoud Al Rifai, David I Feldman, Kevin L Billups, Clinton A Brawner, Zeina A Dardari, Jonathan K Ehrman, Steven J Keteyian, Mouaz H Al-Mallah, Michael J Blaha
BACKGROUND: Vascular erectile dysfunction (ED) has been identified as a potentially useful risk factor for predicting future cardiovascular events, particularly in younger men. Because these men typically score more favorably on traditional cardiovascular disease risk assessment tools, there exists a gap in knowledge for how to most appropriately identify those men who would benefit from more aggressive treatments. To date, no studies have examined the impact of fitness on cardiovascular outcomes in men with ED...
August 14, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28805947/penile-neurovascular-structure-revisited-immunohistochemical-studies-with-three-dimensional-reconstruction
#16
G N Yin, S-H Park, M-J Choi, A Limanjaya, K Ghatak, N N Minh, J Ock, K-M Song, J-K Ryu, J-K Suh
Penile erection is a neurovascular phenomenon that requires well coordinated and functional interaction between penile vascular and nervous systems. In order to provide a useful tool to examine pathologic changes in the erectile tissue, mainly focusing on penile neurovascular dysfunction, we established the technique to determine the differential distribution of endothelial cells, smooth muscle cells, pericytes, and nerve fibers in the mouse penis using immunohistochemical staining with three-dimensional reconstruction...
August 14, 2017: Andrology
https://www.readbyqxmd.com/read/28781215/adipose-derived-stem-cell-derived-exosomes-ameliorate-erectile-dysfunction-in-a-rat-model-of-type-2-diabetes
#17
Fengzhi Chen, Haibo Zhang, Zhiqiang Wang, Wei Ding, Qinyu Zeng, Wenbing Liu, Can Huang, Shuhua He, Anyang Wei
BACKGROUND: The efficacy of adipose-derived stem cells (ADSCs) in alleviating erectile dysfunction (ED) of diabetic rats has been demonstrated mainly through a paracrine effect. However, exosomes (EXOs), which are important bioactive substance vectors secreted by ADSCs, have never been associated with ED. AIM: To investigate the effect of ADSC-derived EXOs on erectile function in a type 2 diabetic ED rat model. METHODS: EXOs were isolated from the supernatants of cultured ADSCs by ultracentrifugation...
August 3, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28749782/erection-stimulating-anti-diabetic-and-antioxidant-properties-of-hunteria-umbellata-and-cylicodiscus-gabunensis-water-extractable-phytochemicals
#18
Ganiyu Oboh, Adeniyi A Adebayo, Ayokunle O Ademosun
Background Herbs have been used as an aphrodisiac since ages. This study was designed to investigate the effects of Hunteria umbellata (HU) seeds and Cylicodiscus gabunensis (CG) stem barks aqueous extracts on key enzymes relevant to erectile dysfunction (phosphodiesterase-5 and arginase) and type-2 diabetes (α-amylase and α-glucosidase). Methods In ascertaining the erectogenic and antidiabetic properties of the extracts, the effects of the extracts on activities of some enzymes relevant to erectile dysfunction (arginase and phosphodiesterase-5) and type-2 diabetes (α-amylase and α-glucosidase) were determined...
July 26, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28748676/relationship-between-erectile-dysfunction-comorbidity-and-parkinson-s-disease-evidence-from-a-population-based-longitudinal-study
#19
Yuwan Yang, Hsinho Liu, Tienhuang Lin, Yuhung Kuo, Tengfu Hsieh
BACKGROUND AND PURPOSE: To determine the risk of Parkinson's disease (PD) in relation to erectile dysfunction (ED) based on the National Health Insurance Research Database in Taiwan. METHODS: We identified 3,153 patients who were newly diagnosed with ED between January 1, 2004 and December 31, 2010. A total of 12,612 randomly selected people without ED served as healthy controls. All of the study subjects were followed-up from the index date to the date of PD diagnosis, withdrawal from the National Health Insurance program, or the end of 2012 whichever occurred first...
July 2017: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/28725599/effects-of-metformin-on-endothelial-health-and-erectile-dysfunction
#20
REVIEW
Jay Pravin Patel, Eric Hweegeun Lee, Carlos Ignacio Mena, Charles N Walker
Erectile dysfunction (ED) affects approximately 18 million American men. ED may be attributed to several etiologies, including arteriogenic, psychogenic, neurogenic, hormonal, drug-induced, and systemic disease or aging related factors. Specific to arteriogenic ED, three major mechanisms have been identified: (I) endothelium-dependent vasodilatory impairment; (II) sympathetic nerve activity elevation; (III) atherosclerotic luminal narrowing. Additionally, these insults have been linked to the insulin resistant state, which in turn is comorbid with obesity, dyslipidemia, diabetes, and hypertension...
June 2017: Translational Andrology and Urology
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