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Isopropyl alcohol

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https://www.readbyqxmd.com/read/28796919/evaluation-of-a-needle-disinfectant-technique-to-reduce-infection-related-hospitalization-following-transrectal-prostate-biopsy
#1
Gregory B Auffenberg, Ji Qi, Yuqing Gao, David C Miller, Zaojun Ye, Andrew Brachulis, Susan Linsell, Tejal N Gandhi, David Kraklau, James E Montie, Khurshid R Ghani
OBJECTIVES: To determine whether a needle disinfectant technique during transrectal prostate biopsy is associated with lower rates of infection-related hospitalization. SUBJECTS AND METHODS: We conducted a retrospective analysis of all transrectal prostate biopsies performed across the Michigan Urological Surgery Improvement Collaborative (MUSIC) from January 2012 through March 2015. Natural variation in technique allowed us to evaluate for differences in infection-related hospitalizations based on whether or not a needle disinfectant technique was utilized...
August 10, 2017: BJU International
https://www.readbyqxmd.com/read/28795792/lu2-c82-nanorods-with-enhanced-photo-luminescence-and-photoelectrochemical-properties
#2
Wangqiang Shen, Li Zhang, ShuShu Zheng, Yun-Peng Xie, Xing Lu
One-dimensional (1D) single-crystalline hexagonal nanorods of Lu2@C3v(8)-C82 were prepared for the first time using the liquid-liquid interface precipitation method (LLIP) from the interfaces between carbon disulfide (CS2) and isopropyl alcohol (IPA). The length of the nanorods can be readily controlled by varying the concentration of the Lu2@C82 solution in addition to the volume ratio of CS2 to IPA. The latter factor also exhibits a significant influence on the morphology of the crystals. The crystalline structure of the nanorods has been investigated by XRD and selected area electron diffraction (SAED), suggesting a face-centered cubic structure...
August 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28780437/elemental-mercury-removal-from-flue-gas-by-cofe2o4-catalyzed-peroxymonosulfate
#3
Yi Zhao, Xiaoying Ma, Peiyao Xu, Han Wang, Yongchun Liu, Anen He
A magnetic cobalt ferrite (CoFe2O4) catalyst was prepared by sol-gel method, and characterized by a X-Ray Diffraction (XRD), Scanning Electron Microscope (SEM), Brunauer-Emmett-Teller (BET) and hysteresis loop method. The chemical states on surface of the fresh and spent catalysts were analyzed by a X-ray photoelectron spectroscopy (XPS). The experiments of elemental mercury (Hg(0)) removal from flue gas were conducted in a laboratory scale using activated peroxymonosulfate (PMS) catalyzed by CoFe2O4, and the effects of the dosage of catalyst, the concentration of PMS, initial solution pH and reaction temperature on mercury removal efficiency were investigated...
July 29, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28772091/riding-high-into-the-danger-zone-a-review-of-potential-differences-in-chemical-exposures-in-fighter-pilots-resulting-from-high-altitude-and-g-forces
#4
Matthew W Linakis, Kathleen M Job, Xiaoxi Liu, Scott C Collingwood, Heather A Pangburn, Darrin K Ott, Catherine M T Sherwin
When in flight, pilots of high performance aircraft experience conditions unique to their profession. Training flights, performed as often as several times a week, can expose these pilots to altitudes in excess of 15 km (~50,000 ft, with a cabin pressurized to an altitude of ~20,000 ft), and the maneuvers performed in flight can exacerbate the G-forces felt by the pilot. While the pilots specifically train to withstand these extreme conditions, the physiologic stress could very likely lead to differences in the disposition of chemicals in the body, and consequently, dangerously high exposures...
August 3, 2017: Expert Opinion on Drug Metabolism & Toxicology
https://www.readbyqxmd.com/read/28768592/effect-of-hand-lotion-on-the-effectiveness-of-hygienic-hand-antisepsis-implications-for-practicing-hand-hygiene
#5
Helga Paula, Nils-Olaf Hübner, Ojan Assadian, Katja Bransmöller, Romy Baguhl, Harald Löffler, Axel Kramer
BACKGROUND: Skin protection products should be used after washing hands with soap, during breaks, after work, and during leisure time. Aside from their beneficial effects, skin care products may also interact with alcohol-based hand disinfectants by reducing their efficacy. The aim of this study was to investigate the effect of a hand lotion on the effectiveness of hygienic hand antisepsis using an alcohol-based handrub. METHODS: The effect of a protective hand lotion against an isopropyl alcohol-based handrub was investigated in 20 healthy volunteers according to the European standard test procedure EN 1500 in the following combinations: handwashing and application of hand lotion, only application of hand lotion, and no washing and no hand lotion (control), each for 5 minutes or 1 hour before hand antisepsis...
August 1, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28763758/simultaneous-determination-of-three-di-caffeoylquinic-acids-by-uhplc-ms-ms-in-rat-plasma-and-its-application-to-a-comparative-pharmacokinetic-study-in-normal-and-acute-lung-injury-rat
#6
Yanjuan Wang, Yanmin Wang, Xiao Wu, Zhili Xiong, Wei Xiao, Chao Ma
Acute lung injury (ALI) is a severe inflammatory disease with high mortality rates. Di-caffeoylquinic acids (DCQAs), the bioactive components of reduning injection (RDN), may play important roles in the protective effect on acute lung injury (ALI). A selective and rapid ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method has been developed and validated for the simultaneous determination of 3,4-, 3,5- and 4,5-DCQA in rat plasma. The DCQAs were extracted by liquid-liquid extraction with ethyl acetate-isopropyl alcohol (7:3, v/v)...
July 25, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28755490/metabolic-engineering-of-isopropyl-alcohol-producing-escherichia-coli-strains-with-13-c-metabolic-flux-analysis
#7
Nobuyuki Okahashi, Fumio Matsuda, Katsunori Yoshikawa, Tomokazu Shirai, Yoshiko Matsumoto, Mitsufumi Wada, Hiroshi Shimizu
Metabolic engineering of isopropyl alcohol (IPA)-producing E. coli strains was conducted along with (13) C-metabolic flux analysis (MFA). A metabolically engineered E. coli strain expressing the adc gene derived from Clostridium acetobutylicum and the IPADH gene from C. beijerinckii did not produce IPA during its exponential growth phase in the aerobic batch culture. (13) C-MFA was carried out, and revealed a deficiency in NADPH regeneration for IPA production in growth phase. Based on these findings, we used nitrogen-starved culture conditions to reduce NADPH consumption for biomass synthesis...
July 29, 2017: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/28753970/reversed-phase-uhplc-enantiomeric-separation-of-rasagiline-salts-using-a-chiralpak-%C3%A2-agp-column
#8
Nagarajan Balaji, Sayeeda Sultana
We report the first rapid ultra-high performance liquid chromatographic (UHPLC) enantiomeric reversed-phase separation of rasagiline mesylate and its tartrate salts using a Chiralpak(®) AGP column (50 mm × 2.1 mm, 5 μm) as a stationary phase. This method was developed as an alternative to the usage of previously reported normal-phase chiral LC columns for isomer separation. Our method is based on an isocratic approach using a mixture of ammonium acetate and isopropyl alcohol (90:10, v/v) as the mobile phase (0...
July 19, 2017: Scientia Pharmaceutica
https://www.readbyqxmd.com/read/28729139/endoscope-drying-and-its-pitfalls
#9
REVIEW
J Kovaleva
Inadequate drying of endoscope channels is a possible cause of replication and survival of remaining pathogens during storage. The presence during storage of potentially contaminated water in endoscope channels may promote bacterial proliferation and biofilm formation. An incomplete drying procedure or lack of drying and not storing in a vertical position are the most common problems identified during drying and endoscope storage. Inadequate drying and storage procedures, together with inadequate cleaning and disinfection, are the most important sources of endoscope contamination and post-endoscopic infection...
July 17, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28711498/promotion-of-hair-growth-by-newly-synthesized-ceramide-mimetic-compound
#10
Bu-Mahn Park, Soon-Sun Bak, Kyung-Oh Shin, Minhee Kim, Daehwan Kim, Sang-Hun Jung, Sekyoo Jeong, Young Kwan Sung, Hyun Jung Kim
Based on the crucial roles of ceramides in skin barrier function, use of ceramides or their structural mimetic compounds, pseudoceramides, as cosmetic ingredients are getting more popular. While currently used pseudoceramides are intended to substitute the structural roles of ceramides in stratum corneum, development of bioactive pseudoceramides has been repeatedly reported. In this study, based on the potential involvement of sphingolipids in hair cycle regulation, we investigated the effects of newly synthesized pseudoceramide, bis-oleamido isopropyl alcohol (BOI), on hair growth using cultured human hair follicles and animal models...
July 13, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28705429/disinfection-of-tonometers-a-report-by-the-american-academy-of-ophthalmology
#11
Anna K Junk, Philip P Chen, Shan C Lin, Kouros Nouri-Mahdavi, Sunita Radhakrishnan, Kuldev Singh, Teresa C Chen
OBJECTIVE: To examine the efficacy of various disinfection methods for reusable tonometer prisms in eye care and to highlight how disinfectants can damage tonometer tips and cause subsequent patient harm. METHODS: Literature searches were conducted last in October 2016 in the PubMed and the Cochrane Library databases for original research investigations. Reviews, non-English language articles, nonophthalmology articles, surveys, and case reports were excluded. RESULTS: The searches initially yielded 64 unique citations...
July 11, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28695953/triaminoborane-bridged-diphosphine-complexes-with-ni-and-pd-coordination-chemistry-structures-and-ligand-centered-reactivity
#12
Kyounghoon Lee, Courtney M Donahue, Scott R Daly
The synthesis, coordination chemistry, and reactivity of two diphosphines containing the cyclic triaminoborane 1,8,10,9-triazaboradecalin (TBD) are described. To evaluate the ligand-centered reactivity of (Ph)TBDPhos and (iPr)TBDPhos, the complexes ((Ph)TBDPhos)MCl2 and ((iPr)TBDPhos)MCl2, where M = Ni and Pd, were prepared and characterized by elemental analysis, multinuclear NMR spectroscopy ((1)H, (13)C, (31)P, and (11)B), and single-crystal X-ray diffraction (XRD). Despite very low boron Lewis acidity in the TBD backbone, ((Ph)TBDPhos)NiCl2 (1) and ((Ph)TBDPhos)PdCl2 (3) react with H2O, alcohols, and hydrated fluoride reagents in the presence of NEt3 to yield trans H-O or H-F addition across the bridgehead N-B bond...
July 25, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28683004/evaluation-of-compatibility-of-a-gum-mastic-liquid-adhesive-and-liquid-adhesive-remover-with-an-alcoholic-chlorhexidine-gluconate-skin-preparation
#13
Marcia Ryder, Collette Duley
The compatibility of a 2% chlorhexidine gluconate/70% isopropyl alcohol (CHG/IPA) skin preparation with a gum mastic liquid adhesive (GMLA) and liquid adhesive remover (LAR) was assessed in healthy volunteers. Twenty subjects completed test material combination with microbial sampling at 3- and 7-day time points. Mean log10 reductions from baseline for normal flora were assessed. There was no significant difference in reduction of normal flora on skin prepped with CHG/IPA versus skin prepped with CHG/IPA followed by GMLA or LAR...
July 2017: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
https://www.readbyqxmd.com/read/28638595/use-of-90-ethanol-to-decontaminate-stethoscopes-in-resource-limited-settings
#14
Bijendra Raj Raghubanshi, Supriya Sapkota, Arjab Adhikari, Aman Dutta, Utsuk Bhattarai, Rastriyata Bhandari
BACKGROUND: In developing countries like Nepal, 90% ethanol is cheap and is available in most hospitals. The unavailability of isopropyl alcohol (IPA) in these settings led us to compare the efficacy between 90% ethanol and isopropyl alcohol pads in reducing the bacterial contamination of diaphragm of stethoscope. METHODS: A randomized blinded experimental study was carried out to determine the difference between cleaning stethoscopes with 90% ethanol and IPA. Cultures of diaphragm were taken before and after cleaning with one of the cleaning agent...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28632074/isopropyl-alcohol-swabs-as-a-preferred-substance-of-abuse
#15
Aditi Sharma, Jonathan D Morrow
The authors describe the treatment of a 36-year-old woman who presented with excessive consumption of antiseptic alcohol swabs. Her behavior was diagnosed as a severe substance use disorder with isopropyl alcohol as the primary drug of choice. Diagnostic and treatment challenges involved in the case are discussed in detail, with particular focus on the differential diagnosis for this unusual presentation, including obsessive compulsive disorder, pica, and intentional self-injurious behavior. A brief review of the literature on non-ethanol ingestion for the purposes of intoxication is included, as well as clinical information about the potential dangers posed by isopropyl alcohol consumption...
February 26, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28626130/examination-of-a-new-desorption-method-for-solid-adsorption-method-of-working-environment-measurement-%C3%AF-attempt-to-improve-desorption-efficiency-of-organic-solvents-from-a-coconut-shell-activated-carbon-using-surfactant-solutions%C3%AF
#16
Mitsuo Hinoue, Hajime Hori
For a new desorption method development for working environment measurement, desorption efficiency of organic solvent vapors from an activated carbon was examined using desorption solutions that consisted of anionic and nonionic surfactants. Ten μl of an aqueous solution of isopropyl alcohol or methyl ethyl ketone diluted with distilled water was spiked into a 10 ml vial with a coconut-shell-activated carbon (100 mg). The vial was left for 24 h, and 5 ml a desorption solution was added. Afterwards, the vial was put into an incubator at 60°C and left for 24 h, then the desorption efficiency was determined by analyzing the headspace gas in the vial with a gas chromatograph equipped with flame ionization detector...
2017: Journal of UOEH
https://www.readbyqxmd.com/read/28617245/efficient-mixed-solvent-exfoliation-of-few-quintuple-layer-bi2s3-and-its-photoelectric-response
#17
Yaohui Guo, Qiyi Zhao, Zehan Yao, Keyu Si, Yixuan Zhou, Xinlong Xu
A scalable liquid exfoliation of layered Bi2S3 employing a mixed-solvent strategy was used for the fabrication of Bi2S3 nanosheets. We found that 10% deionized water in 90% isopropyl alcohol is the best mixed solvent for the efficient and effective exfoliation of layered Bi2S3. These results are consistent with the absorbance spectra and enthalpy of mixing theory. The obtained Bi2S3 nanosheets had few-quintuple layers and were investigated by transmission electron microscopy, atomic force microscopy, and Raman spectroscopy...
June 15, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28560359/analysis-of-plastic-residues-in-maple-sap-and-syrup-collected-from-tubing-systems-sanitized-with-isopropyl-alcohol
#18
Luc Lagacé, Carmen Charron, Mustapha Sadiki
A plastic tubing system operated under vacuum is usually used to collect sap from maple trees during spring time to produce maple syrup. This system is commonly sanitized with isopropyl alcohol (IPA) to remove microbial contamination colonizing the system during the sugar season. Questions have been raised whether IPA would contribute to the leaching of plastic residues in maple sap and syrup coming from sanitized systems. First, an extraction experiment was performed in the lab on commercial plastic tubing materials that were submitted to IPA under harsh conditions...
May 2017: Heliyon
https://www.readbyqxmd.com/read/28522428/characterization-of-new-crystalline-forms-of-hydroxyprogesterone-caproate
#19
Jeffrey Caplette, Timothy Frigo, Michael Jozwiakowski, Helene Shea, Mahmoud Mirmehrabi, Peter Müller
A systematic polymorph screening process was conducted on the steroid hydroxyprogesterone caproate, which had only one previously described orthorhombic crystalline form (A), in order to fully elucidate its solid state properties. Cooling, anti-solvent and evaporative techniques largely reproduced the same polymorph, but slurries in various solvents over two days produced a new triclinic form (B). Experiments at different temperatures in ethyl acetate or isopropyl alcohol confirmed this was an enantiotropic system with a transition temperature of approximately 30°C...
May 15, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28514947/enhanced-chlorhexidine-skin-penetration-with-1-8-cineole
#20
A L Casey, T J Karpanen, B R Conway, T Worthington, P Nightingale, R Waters, T S J Elliott
BACKGROUND: Chlorhexidine (CHG) penetrates poorly into skin. The purpose of this study was to compare the depth of CHG skin permeation from solutions containing either 2% (w/v) CHG and 70% (v/v) isopropyl alcohol (IPA) or 2% (w/v) CHG, 70% (v/v) IPA and 2% (v/v) 1,8-cineole. METHODS: An ex-vivo study using Franz diffusion cells was carried out. Full thickness human skin was mounted onto the cells and a CHG solution, with or without 2% (v/v) 1,8-cineole was applied to the skin surface...
May 17, 2017: BMC Infectious Diseases
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