Read by QxMD icon Read

Rate of force production

Shih-Liang Hsi, Peter Surman, Raida Al-Kassas
A highly sensitive and rapid stability indicating Ultra Performance Liquid Chromatographic (UPLC) method was developed for the quantification and identification of isotretinoin in bulk. Chromatographic separation was developed using a gradient elution in a reversed-phase system at flow rate of 0.5 ml/min with 12 minutes run time. The mobile phase was a gradient mixture of mobile phase A (contained a 30:70:0.5 mixture solution of methanol/Purified water/Glacial Acetic Acid) and mobile phase B (contained a 70:25:4...
March 20, 2018: Pharmaceutical Development and Technology
Jason C Kwan
Bacteria have supplied us with many bioactive molecules for use in medicine and agriculture. However, rates of discovery have decreased as the biosynthetic capacity of the culturable biosphere has been continuously mined for many decades. The as-yet-uncultured biosphere is likely to hold far greater biosynthetic potential, especially where ecological niches favor the selection of therapeutically useful bioactivities. I outline here how metagenomics and other systems biology approaches can be used to gain insight into small-molecule biosynthesis and the selective forces which shape it...
March 2018: MSystems
Chao Wang, Zhi-Yi Hu, Heng Zhao, Wenbei Yu, Sijia Wu, Jing Liu, Lihua Chen, Yu Li, Bao-Lian Su
We report three types of conducting polymers (CPs), polyaniline (PANI), polypyrrole (PPY) and poly (3,4-ethylenedioxythiophene) (PEDOT) to modify the surface of the CdS nanorods to probe their photocorrosion inhibition and photocatalytic hydrogen production. Various characterizations, such as high resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS), cyclic voltammetry (CV) and density function theory (DFT) calculations have been conducted to reveal the intrinsic structure of the as-constructed CPs@CdS (@ means CPs at the surface of CdS) core-shell nanorods...
March 6, 2018: Journal of Colloid and Interface Science
Ji Yeon Hong, Eun Ja Choi, Sun Young Choi, Kapsok Li, Beom Joon Kim
BACKGROUND: Comparative research on the characteristics of filler products is limited, especially in the preclinical analysis of hyaluronic acid (HA) fillers. OBJECTIVE: This study was performed to compare the preclinical characteristics, clinical efficacy, and safety of a new HA filler, IDHF-001, with Restylane SubQ in the treatment of nasolabial folds (NLFs). METHODS: Viscoelasticity and injection force were evaluated. Ninety-one subjects were enrolled in this randomized, patient/evaluator-blind, intraindividual clinical study...
March 13, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Frank Jülicher, Stephan W Grill, Guillaume Salbreux
We review the general hydrodynamic theory of active soft materials that is motivated in partic- ular by biological matter. We present basic concepts of irreversible thermodynamics of spatially extended multicomponent active systems. Starting from the rate of entropy production, we iden- tify conjugate thermodynamic fluxes and forces and present generic constitutive equations of polar active fluids and active gels. We also discuss angular momentum conservation which plays a role in the the physics of active chiral gels...
March 15, 2018: Reports on Progress in Physics
Xiujie Ma, Wei Sun, An Lu, Pei Ma, Chuanyin Jiang
The aim of this study was to investigate whether both suspension training (ST) and traditional training (TT) can improve Sanda athlete's strength quality of trunk muscles and to explore the effect of suspension training on Sanda athletes' trunk muscle power production. Twelve elite Sanda athletes from the Competitive Sports School of Shanghai University of Sport were randomly assigned to experimental group (EG) and control group (CG). EG and CG were regularly trained with suspension training and traditional strength training for 40 minutes three times per week...
December 2017: Journal of Exercise Science and Fitness
Diego Hojsgaard
Polyploid genomes evolve and follow a series of dynamic transfigurations along with adaptation and speciation. The initial formation of a new polyploid individual within a diploid population usually involves a triploid bridge, a two-step mechanism of cell fusions between ubiquitous (reduced) and rare (unreduced) gametes. The primary fusion event creates an intermediate triploid individual with unbalanced genome sets, a situation of genomic-shock characterized by gene expression dysregulation, high dosage sensitivity, disturbed cell divisions, and physiological and reproductive attributes drastically altered...
2018: Frontiers in Plant Science
Dicky Tri Utama, Seung Gyu Lee, Ki Ho Baek, Aera Jang, Jae In Pak, Sung Ki Lee
Objective: This study aimed to observe whether high-pressure processing (HPP) affected aroma development and the degradation rate of umami taste-related ATP breakdown products, specifically inosinic acid in grass-fed beef during vacuum aging. Methods: Strip loin (longissimus lumborum) cuts obtained from six grass-fed Friesian Holstein steers (32 months old) on day 4 post slaughter were vacuum-packed and subjected to pressurization at 300 and 500 MPa for 180 s at 15 ± 2°C...
March 13, 2018: Asian-Australasian Journal of Animal Sciences
Heikki Peltonen, Simon Walker, Anthony C Hackney, Janne Avela, Keijo Häkkinen
Maximum strength training induces various improvements in the rate of force development (RFD) on a group level, but no study has investigated inter-individual adaptations in RFD. Fourteen men (28 ± 6 years old) performed the same 10-week maximum strength and then a 10-week power training program. Maximal force and RFD were recorded during maximal isometric leg extension voluntary contractions repeatedly before every 7th training session (2 sessions/week). After the intervention, subjects were retrospectively divided into three groups based on their RFD improvements: (1) improved only during the maximum strength period (MS-responders, + 100 ± 35%), (2) improved only during the power period (P-responders, + 53 ± 27%) or (3) no improvement at all (non-responders, + 3 ± 9%)...
March 6, 2018: European Journal of Applied Physiology
Dianna J Magliano, Valencia J Martin, Alice J Owen, Ella Zomer, Danny Liew
OBJECTIVE: Recent studies suggest that diabetes may impact work productivity. In the current study, we sought to estimate the lifetime and population impact of diabetes on productivity using the novel measure of "productivity-adjusted life years" (PALYs). RESEARCH DESIGN AND METHODS: Using age-specific mortality rates and a productivity index attributable to diabetes (akin to the quality of life index, but which adjusts for reduction in productivity) and life table modeling, we estimated years of life and PALYs lost to diabetes among Australians with diabetes currently aged 20-65 years, with follow-up until 69 years...
February 28, 2018: Diabetes Care
Peter Alexander, Sam Rabin, Peter Anthoni, Roslyn Henry, Thomas A M Pugh, Mark D A Rounsevell, Almut Arneth
Land use contributes to environmental change, but is also influenced by such changes. Climate and atmospheric carbon dioxide (CO2 ) levels changes alter agricultural crop productivity, plant water requirements and irrigation water availability. The global food system needs to respond and adapt to these changes, for example by altering agricultural practices, including the crop types or intensity of management, or shifting cultivated areas within and between countries. As impacts and associated adaptation responses are spatially specific, understanding the land use adaptation to environmental changes requires crop productivity representations that captures spatial variations...
February 27, 2018: Global Change Biology
Christian Maurer, Sebastian Heller, Jil-Julia Sure, Daniel Fuchs, Christoph Mickel, Eileen M Wanke, David A Groneberg, Daniela Ohlendorf
OBJECTIVE: The influence of the jaw position on postural control, body posture, walking and running pattern has been reported in the literature. All these movements have in common that a relatively small, but well controlled muscle activation is required. The induced effects on motor output through changed jaw positions have been small. Therefore, it has been questioned if it could still be observed in maximal muscle activation. METHOD: Twenty-three healthy, mid age recreational runners (mean age = 34...
2018: PloS One
Matthew Soeberg, Deborah A Vallance, Victoria Keena, Ken Takahashi, James Leigh
The most effective way of reducing the global burden of asbestos-related diseases is through the implementation of asbestos bans and minimising occupational and non-occupational exposure to respirable asbestos fibres. Australia's asbestos consumption peaked in the 1970s with Australia widely thought to have had among the highest per-capita asbestos consumption level of any country. Australia's discontinuation of all forms of asbestos and asbestos-containing products and materials did not occur at a single point of time...
February 23, 2018: International Journal of Environmental Research and Public Health
Yoshiyuki Saito, Nobuyuki Onishi, Hiroshi Takami, Ryo Seishima, Hiroyoshi Inoue, Yuki Hirata, Kaori Kameyama, Kenji Tsuchihashi, Eiji Sugihara, Shinya Uchino, Koichi Ito, Hirofumi Kawakubo, Hiroya Takeuchi, Yuko Kitagawa, Hideyuki Saya, Osamu Nagano
The low turnover rate of thyroid follicular cells and the lack of a long-term thyroid cell culture system have hampered studies of thyroid carcinogenesis. We have now established a thyroid organoid culture system that supports thyroid cell proliferation in vitro. The established mouse thyroid organoids performed thyroid functions including thyroglobulin synthesis, iodide uptake, and the production and release of thyroid hormone. Furthermore, transplantation of the organoids into recipient mice resulted in the formation of normal thyroid-like tissue capable of iodide uptake and thyroglobulin production in vivo...
February 19, 2018: Biochemical and Biophysical Research Communications
Ying Tang, Song Xu, Ping Ao
Quantifying the escape rate from a meta-stable state is essential to understand a wide range of dynamical processes. Kramers' classical rate formula is the product of an exponential function of the potential barrier height and a pre-factor related to the friction coefficient. Although many applications of the rate formula focused on the exponential term, the prefactor can have a significant effect on the escape rate in certain parameter regions, such as the overdamped limit and the underdamped limit. There have been continuous interests to understand the effect of non-detailed balance on the escape rate; however, how the prefactor behaves under strong non-detailed balance force remains elusive...
February 14, 2018: Journal of Chemical Physics
Norman Helm, Olaf Prieske, Thomas Muehlbauer, Tom Krüger, Urs Granacher
BACKGROUND: In judo, rapid force production during pulling movements is an important component of athletic performance, which is why this capacity needs to be specifically exercised in judo. This study aimed at examining the effects of a judo-specific resistance training program using a judo ergometer system (PTJ) versus a traditional resistance training regime using a partner (PTP) on kinetics and muscle activity of judo-specific pulling exercises. METHOD: Twenty-four male judo athletes (age: 22 ± 4 years, training experience: 15 ± 3 years) were randomly assigned to two groups...
February 14, 2018: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
Marie-Eve Cousin, Maria Christina Härdi-Landerer, Verena Völk, Michèle Bodmer
BACKGROUND: Contagious mastitis is an important disease in dairy cattle, and the causative agent S. aureus can also impair raw milk cheese quality. In a confined region in eastern Switzerland attitude, knowledge and behaviour towards S. aureus und S. aureus control was assessed in 90 dairy farmers with communal alpine pasturing including raw milk cheese production with the aid of a questionnaire. RESULTS: Forty-three out of 90 questionnaires were returned (48% return rate)...
February 13, 2018: BMC Veterinary Research
Vanesa Bochkezanian, Robert U Newton, Gabriel S Trajano, Amilton Vieira, Timothy S Pulverenti, Anthony J Blazevich
BACKGROUND: Neuromuscular electrical stimulation (NMES) is commonly used in skeletal muscles in people with spinal cord injury (SCI) with the aim of increasing muscle recruitment and thus muscle force production. NMES has been conventionally used in clinical practice as functional electrical stimulation (FES), using low levels of evoked force that cannot optimally stimulate muscular strength and mass improvements, and thus trigger musculoskeletal changes in paralysed muscles. The use of high intensity intermittent NMES training using wide-pulse width and moderate-intensity as a strength training tool could be a promising method to increase muscle force production in people with SCI...
February 13, 2018: BMC Neurology
Alessio Gallina, Michael A Hunt, Paul Hodges, S Jayne Garland
OBJECTIVE: To compare neural drive, determined from motor unit firing rate, to the vastus medialis and lateralis in females with and without patellofemoral pain. DESIGN: Cross-sectional study. SETTING: University research laboratory. PARTICIPANTS: Females (N=56) 19-35 years old, 36 with patellofemoral pain and 20 controls. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURE(S): Participants sustained an isometric knee extension contraction at 10% of their maximal voluntary effort for 70s...
February 9, 2018: Archives of Physical Medicine and Rehabilitation
Filiz Ateş, Brenda L Davies, Swati Chopra, Krista Coleman-Wood, William J Litchy, Kenton R Kaufman
Intramuscular pressure (IMP) is the hydrostatic fluid pressure that is directly related to muscle force production. Electromechanical delay (EMD) provides a link between mechanical and electrophysiological quantities and IMP has potential to detect local electromechanical changes. The goal of this study was to assess the relationship of IMP with the mechanical and electrical characteristics of the tibialis anterior muscle (TA) activity at different ankle positions. We hypothesized that (1) the TA IMP and the surface EMG (sEMG) and fine-wire EMG (fwEMG) correlate to ankle joint torque, (2) the isometric force of TA increases at increased muscle lengths, which were imposed by a change in ankle angle and IMP follows the length-tension relationship characteristics, and (3) the electromechanical delay (EMD) is greater than the EMD of IMP during isometric contractions...
2018: Frontiers in Physiology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"