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https://www.readbyqxmd.com/read/29166658/episodic-future-thinking-reduces-temporal-discounting-in-healthy-adolescents
#1
Uli Bromberg, Maria Lobatcheva, Jan Peters
Episodic Future Thinking has proven efficient in reducing impulsive behavior in several adult populations. Whether it also has a beneficial impact on decision making in adolescents is not known. Here the impact of episodic future thinking on discounting behavior was investigated in a sample of healthy adolescents (n = 44, age range 13-16 years). Discounting behavior in trials including episodic future thinking was significantly less impulsive than in control trials (t = 2.74, p = .009, dz = .44). In a subsample we controlled for executive function, alcohol use and developmental measures...
2017: PloS One
https://www.readbyqxmd.com/read/29166433/hypoglycemia-caused-by-co-secretion-of-insulin-from-lung-tumor-and-cardia-cancer-first-case-report
#2
Yaning Chen, Yi Kang, Liu Hong, Hebin Yao
CONTEXT: Non-islet-cell-tumor-induced hypoglycemia (NICTH) is caused on rare occasions by secretion of insulin from tumor cells that are reported to have a single tissue origin. CASE REPORT: A 67-year-old male patient had cardia adenocarcinoma and concomitant lung adenocarcinoma with extensive metastases and repeated episodes of intractable hypoglycemia. Immunohistochemical staining for insulin showed that lung adenocarcinoma stained positive and gastric cardia adenocarcinoma stained weakly positive...
November 17, 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/29166376/predictors-of-death-in-infants-with-probable-serious-bacterial-infection
#3
Prashant Singh, Ananya Arora, Tor A Strand, Halvor Sommerfelt, Rakesh Lodha, Sushil Kumar Kabra, Satinder Aneja, Uma Chandra Mouli Natchu, Jagdish Chandra, Bimbadhar Rath, Vinod Kumar Sharma, Mohini Kumari, Savita Saini, Shinjini Bhatnagar, Nitya Wadhwa
INTRODUCTION: Bacterial infections account for a significant proportion of neonatal and infant mortality globally. We aimed to identify predictors of death in infants with probable serious bacterial infection (PSBI) defined as signs/symptoms of possible serious bacterial infection along with baseline C-reactive protein (CRP) ≥12 mg/lMETHODS:We did a secondary analysis using the data collected from 700 infants with PSBI who participated in a randomized controlled trial in India in which zinc or placebo was given in addition to standard antibiotics...
November 22, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29165964/preventing-intradialytic-hypotension-translating-evidence-into-practice
#4
Wendi Bradshaw, Paul N Bennett, Cherene Ockerby, Alison M Hutchinson, Peter G Kerr
Intradialytic hypotension (IDH) remains the most frequent severe side effect of hemodialysis. This prospective, exploratory study aimed to measure the compliance of an IDH prevention pathway and to identify the effects of pathway use on hypotension incidence. Additionally, the study explored barriers and facilitators to pathway implementation in five hemodialysis centers. Instituting an ultrafiltration pause decreased the odds of hypotensive episodes by 44% (OR = 0.56, 95% CI = 0.20 to 1.56, χ2 1 = 1.25, p = 0...
March 2017: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
https://www.readbyqxmd.com/read/29165723/the-impact-of-hyperosmolarity-on-long-term-outcome-in-patients-presenting-with-severe-hyperglycemic-crisis-a-population-based-study
#5
Ivan Kruljac, Miroslav Ćaćić, Petra Ćaćić, Lora Stanka Kirigin Biloš, Davor Kust, Božidar Perić, Maja Filipović-Grčić, Gorana Mirošević, Vedran Ostojić, Mario Štefanović, Milan Vrkljan
Aims We compared characteristics of patients with hyperglycemic hyperosmolar state (HHS) and patients with severe hyperglycemia without the signs of hyperosmolarity and ketoacidosis; analyzed long-term all-cause mortality and potential prognostic factors. Methods The studied population included 261 749 adults. HHS was diagnosed in patients with plasma glucose >33.0 mmol/L, ketonuria <1+, and serum osmolarity >320 mmol/L. Patients with plasma glucose >33.0 mmol/L, ketonuria <1+ and serum osmolarity <320 mmol/L were considered as controls (nHHS)...
November 17, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/29165576/timing-of-first-respiratory-virus-detections-in-infants-a-community-based-birth-cohort-study
#6
Mohinder Sarna, Robert S Ware, Stephen B Lambert, Theo P Sloots, Michael D Nissen, Keith Grimwood
Background: Determining timing of first virus detection episodes (fVDEs) for different respiratory viruses in infants identifies risk periods and informs preventive interventions, including vaccination. We describe the ages and nature of fVDEs in an infant birth cohort, and explore factors associated with increased odds of symptomatic fVDEs. Methods: The Observational Research in Childhood Infectious Diseases (ORChID) study is a community-based birth cohort describing acute respiratory infections in infants until their second birthday...
November 17, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29165559/impact-of-pre-admission-oral-anticoagulation-on-ischaemic-stroke-volume-lesion-pattern-and-frequency-of-intracranial-arterial-occlusion-in-patients-with-atrial-fibrillation
#7
Joanna Dietzel, Sophie K Piper, Rudi Ruschmann, Christian Wollboldt, Tatiana Usnich, Simon Hellwig, Ivana Galinovic, Heinrich J Audebert, Matthias Endres, Kersten Villringer, Jochen B Fiebach, Karl Georg Haeusler
Aims: Therapeutic oral anticoagulation on hospital admission reduces morbidity and mortality after acute ischaemic stroke in patients with atrial fibrillation (AF). The underlying mechanism is not fully understood. In order to assess the impact of INR-level on admission on stroke volume, lesion pattern and the frequency of intracranial arterial occlusion, we analysed serial MRI measurements in AF patients suffering acute ischaemic stroke. Methods: and results This subgroup analysis of the prospective '1000Plus' study included patients with acute ischaemic stroke and known AF or a first episode of AF in hospital...
November 20, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29165226/comparability-of-inflammation-adjusted-vitamin-a-deficiency-estimates-and-variance-in-retinol-explained-by-c-reactive-protein-and-%C3%AE-1-acid-glycoprotein-during-low-and-high-malaria-transmission-seasons-in-rural-zambian-children
#8
Maxwell A Barffour, Kerry J Schulze, Christian L Coles, Justin Chileshe, Ng'andwe Kalungwana, Margia Arguello, Ward Siamusantu, William J Moss, Keith P West, Amanda C Palmer
Inflammation-induced hyporetinolemia (IIH), a reduction in serum retinol (SR) during inflammation, may bias population estimates of vitamin A deficiency (VAD). The optimal adjustment for IIH depends on the type and extent of inflammation. In rural Zambian children (4-8 years, N = 886), we compared three models for defining inflammation: α-1-acid glycoprotein (AGP) only (inflammation present if > 1 g/L or normal if otherwise), C-reactive protein (CRP) only (moderate inflammation, 5-15 mg/L; high inflammation, > 15 mg/L; or normal if otherwise) and a combined model using both AGP and CRP to delineate stages of infectious episode...
November 20, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29165225/prevalence-of-asymptomatic-parasitemia-and-gametocytemia-in-hiv-infected-children-on-differing-antiretroviral-therapy
#9
Charlotte V Hobbs, Erin E Gabriel, Portia Kamthunzi, Gerald Tegha, Jean Tauzie, Yonghua Li, Tiina Ilmet, Elena Artimovich, Jillian Neal, Ted Hall, Sunil Parikh, Brian Kirmse, Patrick Jean-Philippe, Jingyang Chen, William R Prescott, Paul Palumbo, Patrick E Duffy, William Borkowsky, For The P S Study Team
Laboratory data and prior pediatric reports indicate that HIV protease inhibitor (PI)-based antiretroviral therapy (ARV) kills gametocytes and reduces rates of gametocytemia, but not asymptomatic parasitemia, in a high malaria-transmission area. To determine whether ARV regimen impacts these rates in areas with less-intense malaria transmission, we compared asymptomatic parasitemia and gametocytemia rates in HIV-infected children by ARV regimen in Lilongwe, Malawi, an area of low-to-moderate transmission intensity...
November 20, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29165097/a-predictive-model-of-the-prevalence-of-delirium-in-elderly-subjects-admitted-to-nursing-homes
#10
Pilar Perez-Ros, Francisco Miguel Martinez-Arnau, Susana Baixauli-Alacreu, Jose Fermin Garcia-Gollarte, Francisco Tarazona-Santabalbina
INTRODUCTION: Delirium is common in geriatric patients admitted to nursing homes, with an incidence of 22-79% among long-term residents. AIM: To establish a predictive model of the risk of delirium episodes in a sample of elderly people living in nursing homes. MATERIAL AND METHODS: A retrospective, cross-sectional case-control study covering a period of 12 consecutive months (April 2014 - March 2015) was carried out. The included cases had suffered at least one episode of delirium during the study period...
November 20, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29165070/bortezomib-in-kidney-transplant-current-use-and-perspectives
#11
Erika B Rangel, Lucio R Requião-Moura, Taina V de Sandes-Freitas, Gessika Marcelo-Gomes
BACKGROUND: Despite major advances in transplant medicine, antibody-mediated rejection (AMR) continues to have severe clinical implications and adversely affect graft survival. Therefore, the search for alternative drugs to treat AMR is widely pursued. The first-in-class proteasome inhibitor bortezomib (BZ) is a selective inhibitor of the 26S proteasome, which was initially approved for the treatment of malignant plasma cell disorders. METHODS: This review encompasses how our understanding of inhibiting proteasome pathway created the basis of BZ research and important milestones accomplished in AMR treatment in the transplant setting...
November 20, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/29164990/implications-of-stroke-and-bleeding-risk-scores-and-comorbidities-on-episode-based-bundled-payments-for-patients-with-nonvalvular-atrial-fibrillation
#12
Scott Kaatz, Craig I Coleman, Brahim Bookhart, François Laliberté, Winnie W Nelson, Kip Brown, Silas Martin, Jeffrey Schein, Patrick Lefebvre
OBJECTIVES: Due to the high cost of nonvalvular atrial fibrillation (NVAF), this condition may be a suitable candidate for condition-specific bundled payments. This paper evaluates the healthcare cost of NVAF and uses common bleeding and stroke risk scores (HAS-BLED and CHA2DS2-VASc) to explore the risk-based healthcare cost differences among NVAF patients. METHODS: MarketScan claims of NVAF patients (ICD-9-CM code 427.31) were analyzed from 01/2010-04/2015. These claims feature more than 196 million covered lives and more than 300 contributing employers and 25 contributing health plans...
November 22, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29164931/the-clinical-impact-of-neuroimaging-in-first-episode-psychosis
#13
Laura J Pientka, S Charles Schulz, Kelvin O Lim, Suzanne G Jasberg
No abstract text is available yet for this article.
November 22, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/29164792/validity-and-correlates-of-the-international-physical-activity-questionnaire-in-first-episode-psychosis
#14
Davy Vancampfort, Marc De Hert, Inez Myin-Germeys, Simon Rosenbaum, Brendon Stubbs, Tine Van Damme, Michel Probst
AIM: The International Physical Activity Questionnaire (IPAQ) is a self-report tool commonly used in mental healthcare settings to assess physical activity. However, its validity has not yet been investigated in first-episode psychosis (FEP). The aim of this study was to examine the concurrent validity of the IPAQ compared with an objective real-life measure, the Sensewear Armband (SWA), in assessing moderate and vigorous physical activity (MVPA) in people with FEP. A secondary aim was to explore whether there are differences in correlates of the IPAQ vs SWA scores...
November 22, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29164787/factors-related-to-duration-of-untreated-psychosis-of-first-episode-schizophrenia-spectrum-disorder
#15
Yong Qiu, Leijun Li, Zhaoyu Gan, Jihui Wang, Liangrong Zheng, Jiaoshi Zhao, Nianhong Guan, Qinling Wei
AIM: Duration of untreated psychosis (DUP) is associated with outcome and functioning. It is expected that scientists will find factors that modulate DUP, but thus far, research on this topic has shown inconsistent results. Furthermore, similar studies in China are insufficient. This study aims to explore social and clinical factors for DUP in South China and to learn the influence that family plays on DUP through their awareness of psychosis. METHODS: Participants included 216 patients with first episode schizophrenia spectrum disorder...
November 22, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29164565/a-naturally-inspired-curcumin-based-lecithin-formulation-meriva%C3%A2-formulated-as-the-finished-product-algocur%C3%A2-alleviates-the-osteo-muscular-pain-conditions-in-rugby-players
#16
F Di Pierro, P Zacconi, A Bertuccioli, S Togni, R Eggenhoffner, L Giacomelli, S Scaltrini
OBJECTIVE: Curcumin is one of the most investigated phytochemical products because of its low toxicity and its broad spectrum of bioactivity, including anti-inflammatory and analgesic properties. A new delivery form of curcumin, resorting to phosphatidylcholine (Meriva®, formulated as the finished product Algocur®) has been developed to increase its bioavailability. In this study, we tested the efficacy and safety of a Meriva®-based product in rugby players suffering by different osteo-muscular pain conditions PATIENTS AND METHODS: In this pilot study, 50 male rugby players with osteo-muscular pain due to traumatic injuries, physical overload or acute episode of chronic pain were recruited and treated with conventional analgesic drugs (n = 25) or Meriva®-based product (n = 25) for a maximum of 10 days...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29164495/the-clinical-trajectory-of-emerging-bipolar-disorder-among-the-high-risk-offspring-of-bipolar-parents-current-understanding-and-future-considerations
#17
REVIEW
A Duffy, C Vandeleur, N Heffer, M Preisig
BACKGROUND: Relatively little is known about the onset of bipolar disorder, yet the early illness course is already associated with significant morbidity and mortality. Therefore, characterizing the bipolar illness trajectory is key to risk prediction and early intervention advancement. MAIN BODY: In this narrative review, we discuss key findings from prospective longitudinal studies of the high-risk offspring of bipolar parents and related meta-analyses that inform us about the clinical trajectory of emerging bipolar disorder...
November 22, 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/29164354/associations-between-major-depressive-episode-methamphetamine-use-disorder-severity-and-engagement-in-sexual-risk-taking-among-methamphetamine-using-men-who-have-sex-with-men
#18
Jesse B Fletcher, Dallas Swendeman, Cathy J Reback
Depression and methamphetamine use have been associated with increased sexual risk-taking among men who have sex with men (MSM). This study estimated associations between current major depressive episode and/or methamphetamine use disorder and engagement in condomless anal intercourse (CAI). From March 2014 thru January 2016, 286 methamphetamine-using MSM were enrolled into a RCT to reduce methamphetamine use and sexual risk-taking. Analyses revealed that current major depressive episode was associated with a 92% increase in the rate of engagement in CAI with casual male partners (IRR 1...
November 21, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29164332/individual-trajectories-of-cognitive-performance-in-first-episode-psychosis-a-2-year-follow-up-study
#19
A M Sánchez-Torres, L Moreno-Izco, R Lorente-Omeñaca, B Cabrera, A Lobo, A M González-Pinto, J Merchán-Naranjo, I Corripio, E Vieta, E de la Serna, A Butjosa, F Contreras, S Sarró, G Mezquida, M Ribeiro, M Bernardo, M J Cuesta
Individual changes over time in cognition in patients with psychotic disorders have been studied very little, especially in the case of first episode psychosis (FEP). We aimed to establish whether change in individual trajectories in cognition over 2 years of a sample of 159 FEP patients was reliable and clinically significant, using the reliable change index (RCI) and clinically significant change (CSC) methods. We also studied a sample of 151 matched healthy controls. Patients and controls were assessed with a set of neuropsychological tests, as well as premorbid, clinical and functionality measures...
November 21, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29164294/a-novel-technique-of-paravertebral-thoracic-and-preperitoneal-analgesia-enhances-early-recovery-after-oesophagectomy
#20
Stephanie Phillips, Jasmina Dedic-Hagan, d'Arcy Ferris Baxter, H Van der Wall, G L Falk
BACKGROUND: Excellent analgesia following oesophagectomy facilitates patient comfort, early extubation, physiotherapy and mobilisation, reduces post-operative complications and should enhance recovery. Thoracic epidural analgesia (TEA), the gold standard analgesic regimen for this procedure, is often associated with systemic hypotension treated with inotropes or fluid. This may compromise enhanced recovery and be complicated by anastomotic ischaemia or tissue oedema. METHODS: We report a novel analgesic regimen to reduce post-operative inotrope usage...
November 21, 2017: World Journal of Surgery
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