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Anemia in female adults

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https://www.readbyqxmd.com/read/29765285/anemia-and-thrombocytopenia-in-the-cohort-of-hiv-infected-adults-in-northwest-ethiopia-a-facility-based-cross-sectional-study
#1
Tekalign Deressa, Debasu Damtie, Meseret Workineh, Meaza Genetu, Mulugeta Melku
Background: Anemia and thrombocytopenia are frequent hematological abnormalities in patients with human immunodeficiency virus (HIV) infection and have been associated with increased morbidity and mortality. However, there is a paucity of data on the prevalence and correlates of these hematological abnormalities among HIV infected adults in Ethiopia. The aim of this study was to determine the prevalence and correlates of anemia and thrombocytopenia in a cohort of HIV-1 infected adults in northwest Ethiopia...
April 2018: EJIFCC
https://www.readbyqxmd.com/read/29750173/radiotherapy-for-adult-medulloblastoma-evaluation-of-helical-tomotherapy-volumetric-intensity-modulated-arc-therapy-and-three-dimensional-conformal-radiotherapy-and-the-results-of-helical-tomotherapy-therapy
#2
Sun Zong-Wen, Yang Shuang-Yan, Du Feng-Lei, Cheng Xiao-Long, Li Qinglin, Chen Meng-Yuan, Hua Yong-Hong, Jin Ting, Hu Qiao-Ying, Chen Xiao-Zhong, Chen Yuan-Yuan, Chen Ming
Introduction: All adult medulloblastoma (AMB) patients should be treated with craniospinal irradiation (CSI) postoperatively. Because of the long irradiation range, multiple radiation fields must be designed for conventional radiotherapy technology. CSI can be completed in only one session with helical tomotherapy (HT). We evaluated the dose of HT, volumetric intensity modulated arc therapy (VMAT), and three-dimensional conformal radiotherapy (3D-CRT) of AMB and the results of 5 cases of AMB treated with HT...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29709046/prevalence-and-predictors-of-readmissions-among-adults-with-cystic-fibrosis-in-the-united-states
#3
Kshitij Chatterjee, Abhinav Goyal, Deepak Reddy, Vikas Koppurapu, Ayoub Innabi, Bashar Alzghoul, Rajani Jagana
INTRODUCTION: Patients with Cystic Fibrosis (CF) have increasing rates of hospitalization. We analyzed the burden and predictors of thirty-day readmission among patients with CF in the U.S. MATERIAL AND METHODS: Nationwide Readmission Database (NRD) 2013 was used to identify adults with CF who were hospitalized. These individuals were followed to determine the prevalence of readmission within thirty days of index discharge. Cox proportional hazard regression was used to identify independent predictors of readmission...
2018: Advances in Respiratory Medicine
https://www.readbyqxmd.com/read/29704448/establishment-of-new-complete-blood-count-reference-values-for-healthy-thai-adults
#4
P Wongkrajang, W Chinswangwatanakul, C Mokkhamakkun, N Chuangsuwanich, B Wesarachkitti, B Thaowto, S Laiwejpithaya, O Komkhum
INTRODUCTION: Laboratory reference ranges are essential for diagnostic orientation and treatment decision. As complete blood count parameters are influenced by various factors, including gender, geographic origin, and ethnic origin, it is important to establish specific hematologic reference values for specific populations. METHODS: This study was conducted at the Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand...
April 28, 2018: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/29657196/atypical-hemolytic-uremic-syndrome-a-monocentric-adult-tunisian-study-and-review-of-literature
#5
R Kherder-Elfekih, M Hajji, L Ben Fatma, H Jebali, I Mami, W Smaoui, M Krid, L Rais, S Beji, K Zouaghi, M Sellami-Kallel
Atypical hemolytic uremic syndrome (aHUS) is characterized by microvascular thrombosis resulting in thrombocytopenia, hemolytic anemia, and multiorgan dysfunction. It is associated with genetic or acquired disorders of regulatory components of the complement system. For our study, we collected data from 16 patients diagnosed with aHUS between January 2010 and January 2014. The mean age was 33.6 years. The female-to-male ratio was 3. The median follow-up duration was 27 ± 3.5 months. The most common clinical presentation was hypertension...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29614584/-glycogen-storage-disease-type-%C3%A2-a-a-rare-cause-of-gout-in-adolescent-and-young-adult-patients
#6
N Xu, X M Huang, W G Fang, Y Zhang, Z Q Qiu, X J Zeng
Objective: To analyze the clinical features of secondary gout in glycogen storage disease type Ⅰa (GSD Ⅰa), so as to improve the awareness of this disease. Methods: The clinical features, laboratory findings, treatments and prognosis of 5 GSD Ⅰa patients with secondary gout who had been admitted to the Peking Union Medical College Hospital during 2006 to 2016 were collected and analyzed. GSD Ⅰa was confirmed by liver biopsy and genotyping. Results: Among the 5 patients (median age: 27 years), 3 were males and 2 were females...
April 1, 2018: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29609084/risk-factors-for-thirty-day-morbidity-and-mortality-in-extradural-lumbar-spine-tumor-resection
#7
Christopher A Sarkiss, Eliza H Hersh, Travis R Ladner, Nathan Lee, Parth Kothari, Nikita Lakomkin, John M Caridi
BACKGROUND: Epidural tumors in the lumbar spine represent a unique cohort of lesions with individual risks and challenges to resection. Knowledge of modifiable risk factors are important in minimizing postoperative complications. OBJECTIVE: To determine the risk factors for 30-day morbidity and mortality in patients undergoing extradural lumbar tumor resection. METHODS: A retrospective study of prospectively collected data utilizing the ACS-NSQIP database was performed...
March 30, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29582203/prevalence-and-types-of-anemia-in-a-large-refugee-cohort-in-western-europe-in-2015
#8
Alexandra Jablonka, Martin Wetzke, Georgios Sogkas, Christian Dopfer, Reinhold Ernst Schmidt, Georg M N Behrens, Christine Happle
Currently, vast numbers of migrants with largely unknown health statuses have been entering Europe. To improve care taking strategies, prevalence, severity and types of anemia in a large refugee cohort were assessed. Blood counts were performed in n = 787 inhabitants from six German refugee centers. Most included migrants were young, male adults. Anemia was present in 22.5% of subjects with an age-dependent prevalence increase (7.9% > 18 years vs. 30.8% > 50 years). More females than males were anemic (27...
March 26, 2018: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29535933/diabetic-retinopathy-awareness-and-associations-with-multiple-comorbidities-insights-from-diamond-study
#9
Kiran Shah, Alka Gandhi, Sundaram Natarajan
Background: Diabetic retinopathy (DR) is leading cause of visual impairment in working-age adults. Macular edema can occur with or without other signs of retinopathy. Methods: This was a single-center, retrospective study conducted over 2 years in patients (>40 years of age) having type 2 diabetes mellitus (T2DM). Outcome measures were to analyze awareness and prevalence of DR and association of DR with identified risk factors. Results: Overall 6000 T2DM patients over 2 years were retrospectively evaluated...
January 2018: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29519371/mortality-in-children-adolescents-and-adults-with-sickle-cell-anemia-in-rio-de-janeiro-brazil
#10
Clarisse Lopes de Castro Lobo, Emilia Matos do Nascimento, Leonardo José Carvalho de Jesus, Thiago Gotelip de Freitas, Jocemir Ronaldo Lugon, Samir K Ballas
OBJECTIVE: To determine the mortality rate of children, adolescents and adults with sickle cell anemia in Rio de Janeiro, Brazil. METHODS: The number of deaths, the mortality rate and the causes of deaths in patients with sickle cell anemia who were treated and followed up at our institution for 15 years were determined and compared to data available for the Brazilian population. RESULTS: The overall number of deaths was 281 patients with a mortality rate of 16...
January 2018: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/29506549/lipid-profiles-in-french-west-indies-sickle-cell-disease-cohorts-and-their-general-population
#11
Marie-Laure Lalanne-Mistrih, Philippe Connes, Yann Lamarre, Nathalie Lemonne, Marie-Dominique Hardy-Dessources, Vanessa Tarer, Maryse Etienne-Julan, Dominique Mougenel, Benoît Tressières, Marc Romana
BACKGROUND: The pathophysiology of sickle cell disease (SCD) and the variability of its clinical expression remain not fully understood, whether within or between different SCD genotypes. Recent studies have reported associations between lipid levels and several SCD complications. If lipid levels have been previously described as low in sickle cell anemia (SCA), few data have been provided for sickle cell SC disease (SCC). We designed our epidemiological study to isolate lipid levels and profiles by genotype in Guadeloupian cohorts of SCA and SCC adult patients, at steady state...
March 5, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29432304/anemia-in-adolescents-and-young-adult-patients-with-congenital-heart-disease
#12
Juan L Rodríguez-Hernández, Fayna Rodríguez-González, Efrén Martínez-Quintana
INTRODUCTION: Despite anemia in acquired heart disease being a common problem, little is known in patients with congenital heart disease (CHD). METHODS: In total, 544 consecutive stable noncyanotic CHD patients were studied to determine demographic, clinical, and analytic parameters. Anemia was defined as a condition in which hemoglobin concentration was <13 g/dL in male individuals and <12 g/dL in female individuals. RESULTS: In total, 49 (9%) CHD patients had anemia...
February 9, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29400658/human-erythrocyte-lifespan-measured-by-levitt-s-co-breath-test-with-newly-developed-automatic-instrument
#13
Hou-De Zhang, Yong-Jian Ma, Qi-Fa Liu, Tie-Zhen Ye, Fan-Yi Meng, Yi-Wen Zhou, Guo-Pan Yu, Jian-Ping Yang, Hua Jiang, Quan-Shi Wang, Gui-Ping Li, Yong-Qiang Ji, Guo-Liang Zhu, Li-Tao Du, Kun-Mei Ji
Existing standard techniques for erythrocyte (RBC) lifespan measurement, such as quantitation of labeling with isotopes or biotin, are cumbersome and time-consuming. Given that endogenous CO originates mainly from degraded RBCs, a team lead by Levitt developed a CO breath test to enable more efficient RBC lifespan estimation. The purpose of this study was to evaluate the reliability of Levitt's CO breath test method with our newly developed automatic instrument. RBC lifespan measurements conducted by Levitt's CO breath test method were conducted in 109 healthy subjects and 91 patients with chronic hemolytic anemia...
March 9, 2018: Journal of Breath Research
https://www.readbyqxmd.com/read/29302463/prevalence-and-correlates-of-chronic-kidney-disease-in-a-group-of-patients-with-hypertension-in-the-savanah-zone-of-cameroon-a-cross-sectional-study-in-sub-saharan-africa
#14
Ba Hamadou, Jérôme Boombhi, Félicité Kamdem, Adeline Fitame, Sylvie Ndongo Amougou, Liliane Kuate Mfeukeu, Chris Nadège Nganou, Alain Menanga, Gloria Ashuntantang
Background: The prevalence of chronic kidney disease (CKD) is increasing worldwide due to an increase in the risk factors such as hypertension. The greatest burden is in low-income settings, coupled with late diagnosis and limited management resources. This work aimed at studying the prevalence and risk factors of CKD in a group of patients with hypertension in the Savanah zone in Sub-Saharan Africa (SSA). Methods: We carried out a cross-sectional study between January and May 2016 in the regional Hospital of Garoua-Cameroon...
December 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/29296776/intestinal-hephaestin-potentiates-iron-absorption-in-weanling-adult-and-pregnant-mice-under-physiological-conditions
#15
Caglar Doguer, Jung-Heun Ha, Sukru Gulec, Chris D Vulpe, Gregory J Anderson, James F Collins
Regulation of intestinal iron absorption is crucial to maintain body iron levels because humans have no regulated iron-excretory system. Elucidating molecular events that mediate intestinal iron transport is thus important for the development of therapeutic approaches to modify iron absorption in pathological states. The process of iron uptake into duodenal enterocytes is relatively well understood, but less is known about the functional coupling between the iron exporter ferroportin 1 and the basolateral membrane iron oxidase hephaestin (Heph)...
July 25, 2017: Blood Advances
https://www.readbyqxmd.com/read/29233454/does-radiotherapy-prior-to-surgery-improve-long-term-prognosis-in-pediatric-colorectal-cancer-in-lower-and-upper-middle-income-countries-with-limited-resources-our-experience-and-literature-review
#16
Yacoob Omar Carrim, Luvo Gaxa, Francisca van der Schyff, Nndweleni Meshack Bida, Fareed Omar, Zarina Lockhat
Colorectal carcinoma in children and adolescents is extremely rare, with an annual incidence <0.3 cases per million, most frequently reported in the second decade of life. It accounts for severe morbidity and poor prognosis owing to the low index of suspicion, delayed diagnosis, advanced stage at presentation and the aggressive tumor nature. Patients present with abdominal pain, vomiting, constipation, abdominal distension, rectal tenesmus, iron-deficiency anemia, change in bowel habit and weight loss...
December 2017: Journal of the Egyptian National Cancer Institute
https://www.readbyqxmd.com/read/29227722/glucose-phosphate-isomerase-gpi-tadikonda-characterization-of-a-novel-pro340ser-mutation
#17
Ahmar U Zaidi, Prabhakar Kedar, Prasad Rao Koduri, Gerard W Goyette, Steven Buck, Donald E Paglia, Yaddanapudi Ravindranath
After a thirty-year lag, we serendipitously reestablished contact with a patient with glucose phosphate isomerase deficiency and hydrops fetalis first reported in 1987. We now provide a clinical update and provide results of mutation analysis in this patient, from Southern India. The patient now an adult female of 36 years of age has moderate anemia but requires no transfusions except with some intercurrent illnesses. Exome sequencing studies showed a homozygous c.1018C>T (Pro340Ser) mutation in exon 12 of the glucose phosphate isomerase gene and later confirmed by direct sequencing...
November 2017: Pediatric Hematology and Oncology
https://www.readbyqxmd.com/read/29163729/prevalence-comorbidity-and-investigation-of-anemia-in-the-primary-care-office
#18
Shivani Jatin Gandhi, Iris Hagans, Karim Nathan, Krystal Hunter, Satyajeet Roy
Background: Anemia has a myriad of causes and its prevalence is growing. Anemia is associated with increased all-cause hospitalization and mortality in community-dwelling individuals above age 65 years. Our aim was to determine the prevalence and severity of anemia in adult patients in our primary care office and to determine the relationship between anemia and medical comorbidities. Methods: Electronic medical records of 499 adult patients in our suburban internal medicine office were reviewed who had had at least one hemoglobin value and did not undergo moderate to high-risk surgery in the preceding 30 days...
December 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29161993/burden-of-asymptomatic-malaria-anemia-and-relationship-with-cotrimoxazole-use-and-cd4-cell-count-among-hiv1-infected-adults-living-in-gabon-central-africa
#19
Marielle Karine Bouyou Akotet, Jeanne Vanessa Koumba Lengongo, Magloire Ondounda, Eric Kendjo, Arnaud Mongo Delis, Magalie Essomeyo Mebale, Jacques Mari Ndong Ngomo, Noé Patrick M Bondoukwe, Denise Patricia Mawili-Mboumba, Madeleine Okome Nkoumou
 Objective : This study determined the prevalence of asymptomatic Plasmodium (P.) falciparum infection and anemia in adults living with HIV/AIDS (PLHIV) and compared malaria prevalence between 858 HIV-infected (PLHIV) and 272 uninfected individuals in Gabon where such information are lacking. Factors influencing malaria and anemia were also investigated. PATIENTS AND METHODS: Participants were screened for malaria. Available hemoglobin level, socio-demographic and use of prevention or treatment data were compared between both groups...
November 21, 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/29125799/body-growth-and-rapid-hematological-development-support-breath-hold-of-baby-belugas-delphinapterus-leucas-during-subice-transit
#20
Shawn R Noren, Caryn P Poll, Matthew S Edwards
Body size and oxygen stores in the blood and muscle set breath-hold limits in marine mammals, yet these characteristics are understudied in immature cetaceans. We examined body mass and hematology from birth through adulthood in beluga whales (Delphinapterus leucas). At birth, body mass was 8% and 6% of the maximum mass recorded for adult females and males, respectively. Body mass then increased rapidly, approaching an asymptote around 12 yr for females and 18 yr for males. Interestingly, red blood cell counts, hemoglobin content, and hematocrit levels decreased after birth; this neonatal anemia was reversed as levels increased after 2 mo postpartum...
January 2018: Physiological and Biochemical Zoology: PBZ
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