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juglans regia L.

Umar Muzaffer, V I Paul, Nagarajan Rajendra Prasad, Ramasamy Karthikeyan
The present study was aimed to investigate the photoprotective effect of the male flower of J. regia L. (MEJR) against ultraviolet-B induced apoptosis in human skin cells. Human skin epidermal keratinocytes were pretreated with the MEJR (80 µg/ml, has been selected after MTT assay), prior to 30 min UVB-irradiation at a dose of 20 mJ/cm2 . Mitochondrial membrane potential was evaluated using Rhodamine-123 staining; the % apoptosis by Hoechst staining and acridine orange staining; DNA damage was measured by comet assay...
March 2018: Biochemistry and Biophysics Reports
Benzhong Fu, Qianqian Chen, Mi Wei, Jieqian Zhu, Lulu Zou, Guoyuan Li, Lihua Wang
Here, we report the complete genome sequence of Xanthomonas arboricola pv. juglandis DW3F3, a strong pathogenic strain isolated from blighted walnut immature fruit ( Juglans regia L. cv. Qingxiang). The genome consists of a single chromosome (5,144 kb).
February 22, 2018: Genome Announcements
Uzma Noor Shah, Javid Iqbal Mir, Nazeer Ahmed, Sumira Jan, Khalid Majid Fazili
The purpose of investigation was to assess the phytochemical and nutraceutical of walnut in leaf extracts through diverse quantitative and qualitative phytochemical tests followed by array of assays. The screening of 50 elite walnut genotypes which exhibited wide range of discrepancy in terms of phytochemicals as well as their anti-oxidant potential was done. Walnut genotypes displayed maximum divergence in quercetin content (2.86-5.78 mg/100 g) as represented by cluster analysis. The phenolic rich genotypes exhibiting total phenols (37...
February 2018: Journal of Food Science and Technology
Cinzia Calcabrini, Umberto Mancini, Roberta De Bellis, Alessandra Frati, Anna Rita Mastrogiacomo, Giosue Annibalini, Piero Sestili, Luigi Cucchiarini, Vilberto Stocchi, Lucia Potenza
OBJECTIVE: In this research, fatty acid profile and polyphenolic content of an ethanolic extract of walnut from Juglans regia L. collected in Central Italy, were performed. The potential antioxidant and anti-inflammatory effects of the extract were investigated in the human keratinocytes cell line. METHODS: Fatty acid profile was determined by gas chromatography/mass spectrometry analysis, total phenolic content by Folin-Ciocalteu method and aluminum chloride colorimetric method was used for determination of total flavonoids...
January 12, 2018: Current Pharmaceutical Biotechnology
Davood Nasiry, Ali Reza Khalatbary, Hassan Ahmadvand
Objectives: Oxidative stress has a pivotal role in the pathogenesis of diabetic retinopathy (DR). Juglans regia L . (JRL) leaf extract has hypoglycemic and antioxidative properties. This study aimed to determine the ameliorative effects of JRL against diabetic retinopathy. Materials and Methods: The DR rat model was generated by injection of streptozotocin (STZ). A subset of the diabetic rats received JRL or metformin after the onset of hyperglycemia. Histopathology and immunohistochemistry of apoptotic and inflammatory factors were assessed along with biochemical assessments of lipid peroxidation and antioxidant status...
November 2017: Iranian Journal of Basic Medical Sciences
Dan Wang, Yan Mu, Hongjing Dong, Huijiao Yan, Cui Hao, Xiao Wang, Lisi Zhang
Diaphragma juglandis fructus contains various bioactive constituents. Fourteen compounds were isolated from Diaphragma juglandis fructus by preparative high performance liquid chromatography (pre-HPLC) and high-speed counter-current chromatography (HSCCC). Their structures were identified by nuclear magnetic resonance (NMR) and electrospray ionization mass spectrometry (ESI-MS). Compounds (+)-dehydrovomifoliol (12), (6R,9R)-9-hydroxymegastigman-4-en-3-one (13) and (6R,9S)-9-hydroxymegastigman-4-en-3-one (14) are found from Juglans regia L...
December 29, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Mallikarjuna Aradhya, Dianne Velasco, Zakir Ibrahimov, Biimyrza Toktoraliev, David Maghradze, Mirza Musayev, Zviadi Bobokashvili, John E Preece
The distribution and survival of trees during the last glacial maximum (LGM) has been of interest to paleoecologists, biogeographers, and geneticists. Ecological niche models that associate species occurrence and abundance with climatic variables are widely used to gain ecological and evolutionary insights and to predict species distributions over space and time. The present study deals with the glacial history of walnut to address questions related to past distributions through genetic analysis and ecological modeling of the present, LGM and Last Interglacial (LIG) periods...
2017: PloS One
Majid Asadi-Samani, Mohammad-Taghi Moradi, Leila Mahmoodnia, Shahla Alaei, Fatemeh Asadi-Samani, Tahra Luther
BACKGROUND: Obesity and physical inactivity are currently on the rise due to industrialization of the communities, which has recently led to increased incidence of different diseases such as diabetes. Epidemiological studies and figures have demonstrated the growing incidence of diabetes. Relevantly, the side effects of chemical drugs have led patients to use medicinal plants and traditional approaches despite advances in development of chemical drugs. The aim of this review article is to report the medicinal plants and their traditional uses to prevent and treat diabetes according to the findings of ethnobotanical studies conducted in different regions of Iran...
July 2017: Journal of Nephropathology
Davood Nasiry, Ali Reza Khalatbary, Hassan Ahmadvand, Fereshteh Talebpour Amiri, Esmaeil Akbari
BACKGROUND: Oxidative stress has a pivotal role in the pathogenesis and development of diabetic peripheral neuropathy (DPN), the most common and debilitating complications of diabetes mellitus. There is accumulating evidence that Juglans regia L. (GRL) leaf extract, a rich source of phenolic components, has hypoglycemic and antioxidative properties. This study aimed to determine the protective effects of Juglans regia L. leaf extract against streptozotocin-induced diabetic neuropathy in rat...
October 2, 2017: BMC Complementary and Alternative Medicine
Wilman Carrillo, José Angel Gómez-Ruiz, Ana Lucia Ruiz, Jõao Ernesto Carvalho
Proteins from Juglans regia L. were isolated. Then, proteins were hydrolyzed with different enzymes. Antiproliferative activity of proteins and of the protein hydrolysates of J. regia L. were evaluated using the sulforhodamine B method. Glutelin and prolamin proteins presented a high antiproliferative activity against cancer cells PC-3 (prostate) and K-562 (leukemia) with values of 43.9 and 84.4 μg/mL, respectively. The highest inhibitory effect observed was 50% at 0.25 μg/mL concentration in gastrointestinal digestion with pepsin and corolase pp in a dose-dependent manner against cancer cell UACC62 (melanoma)...
November 2017: Journal of Medicinal Food
Sebastian Schwindl, Birgit Kraus, Jörg Heilmann
A methanolic extract of Juglans regia L. leaves was fractioned by various chromatographic techniques yielding a total of 40 metabolites belonging to megastigmane, tetralone, phenylpropanoid, neolignane and juglone glycosides. Ten unknown megastigmane glucoside derivatives (juglanionosides A-K, 1-10) and six unknown tetralone glucoside derivatives (juglanosides J-O, 11-16) together with 24 known compounds - among them 16 described for the first time in Juglans - were isolated. As characteristic structural feature, the previously undescribed compounds showed acylation of the sugar units with sinapic, ferulic, coumaric, benzoic or salicylic acid...
December 2017: Phytochemistry
Stefano Moscatello, Simona Proietti, Angela Augusti, Andrea Scartazza, Robert P Walker, Franco Famiani, Alberto Battistelli
The effect of late summer - autumn limitation of phloem export on growth, photosynthesis and storage carbohydrate accumulation, was evaluated in walnut (Juglans regia L.). This was done by girdling current years shoots, with either all or with only a third of the leaves left in place. Nineteen days after girdling, photosynthesis was greatly reduced and after 46 days, it was about 70% lower in both girdling treatments compared to the control (ungirdled shoots). This reduction is consistent with a feed-back effect of an increased carbohydrate content of the leaves...
July 31, 2017: Plant Physiology and Biochemistry: PPB
Wladimir Roor, Heino Konrad, Davletbek Mamadjanov, Thomas Geburek
Juglans regia is an economically highly important species for fruit and wood production in the warm temperate and subtropical zones of the Northern Hemisphere. Besides the natural influence of climatic and geomorphological barriers, its genetic structure has been strongly modified by humans and the population history is still unclear. For this reason, we investigated mainly natural walnut populations across the Eurasian continent on a molecular (44 populations, 581 trees) and morphometric level (23 populations, 1391 ripe nuts)...
June 1, 2017: Journal of Heredity
Claudia Fuentealba, Ignacia Hernández, Sebastian Saa, Lea Toledo, Pamela Burdiles, Rosana Chirinos, David Campos, Patrick Brown, Romina Pedreschi
Walnuts (Juglans regia L.) are well known for their flavour, nutritional and health properties. The light colour of walnuts is a quality attribute that leads to consumer preference. The aim of this study was to correlate attributes such as colour and antioxidant capacity with the precursors of primary and secondary metabolism. Two growing areas and four different colours of walnuts cv. Chandler from the central region of Chile were evaluated. Walnuts grown in the zone with Andes Mountains influence showed higher (p<0...
October 1, 2017: Food Chemistry
Aude Tixier, Or Sperling, Jessica Orozco, Bruce Lampinen, Adele Amico Roxas, Sebastian Saa, J Mason Earles, Maciej A Zwieniecki
During spring, bud growth relies on long-distance transport of remotely stored carbohydrates. A new hypothesis suggests this transport is achieved by the interplay of xylem and phloem. During the spring, carbohydrate demand of developing buds often exceeds locally available storage, thus requiring the translocation of sugars from distant locations like limbs, stems and roots. Both the phloem and xylem have the capacity for such long-distance transport, but their functional contribution is unclear. To address this ambiguity, the spatial and temporal dynamics of carbohydrate availability in extension shoots of Juglans regia L...
May 9, 2017: Planta
Cinzia Calcabrini, Roberta De Bellis, Umberto Mancini, Luigi Cucchiarini, Vilberto Stocchi, Lucia Potenza
Walnuts (Juglans regia L.) are relevant components of the Mediterranean diet providing important macronutrients, micronutrients and other bioactive constituents including unsaturated fatty acids, proteins, fiber, vitamins, minerals, phytosterols and polyphenols. Although the walnut beneficial effects in human health are widely recognized by a lot of epidemiologic studies very little is known regarding its effect on damaged DNA. The aim of the present study was to investigate the effect of Juglans regia L. ethanolic extract from kernel on the induction of DNA strand breaks by thiol/Fe3+ /O2 mixed function oxidase, tert-butyl hydroperoxide or UVC radiations in acellular and cellular models...
June 2017: Plant Foods for Human Nutrition
Landry Sarles, Antoine Boullis, Bérénice Fassotte, Georges Lognay, Agnès Verhaeghe, Frédéric Francis, François J Verheggen
BACKGROUND: Several European countries are important walnut (Juglans regia L.) producers. However, these countries must contend with the recent introduction of the Walnut Husk Fly, Rhagoletis completa Cresson (Diptera, Tephritidae), which is causing severe economic losses, especially in organic production. Because most Tephritid fruit flies use kairomones in their search for host plants, we hypothesise that this highly specialist species orients toward the volatile blend released by walnut husks...
April 3, 2017: Pest Management Science
Adriano Mollica, Gokhan Zengin, Marcello Locatelli, Azzurra Stefanucci, Giorgia Macedonio, Giuseppe Bellagamba, Olakunle Onaolapo, Adejoke Onaolapo, Falilat Azeez, Adeola Ayileka, Ettore Novellino
In this study, we evaluated the nutraceutical potential of Juglans regia L. (a dietary supplement and food-additive) by evaluating the in-vitro anti-diabetic potential and by assessing the in-vivo anti-hyperglycaemic, anti-hyperlipidaemic, and organ-protective effects of freshly-dried and powdered leaves of J. regia L. in diabetic rats. In the in-vivo experiments, dry powder of J. regia L. leaf (25, 50 and 100 mg/kg) was administered orally, twice daily (9.00 a.m. and 5 p.m.) to streptozocin-induced diabetic rats over a period of 28 days, during which body weight and blood glucose were monitored weekly...
September 2017: Food and Chemical Toxicology
Varsha Singh, Mingma Sherpa
Mesenchymal stem cells have been extensively used for cell-based therapies especially in neuronal diseases. Studies still continue to delineate mechanisms involved in differentiating mesenchymal stem cells into neuronal cells under experimental conditions as they have low mortality rate and hence, the number of cells available for experiments is much more limited. Culturing and differentiating of neuronal cell is more challenging as they do not undergo cell division thus, bringing them to differentiate proves to be a difficult task...
September 2017: Applied Biochemistry and Biotechnology
Awaz Mohamed, Yogan Monnier, Zhun Mao, Guillaume Lobet, Jean-Luc Maeght, Merlin Ramel, Alexia Stokes
BACKGROUND: Belowground processes play an essential role in ecosystem nutrient cycling and the global carbon budget cycle. Quantifying fine root growth is crucial to the understanding of ecosystem structure and function and in predicting how ecosystems respond to climate variability. A better understanding of root system growth is necessary, but choosing the best method of observation is complex, especially in the natural soil environment. Here, we compare five methods of root image acquisition using inexpensive technology that is currently available on the market: flatbed scanner, handheld scanner, manual tracing, a smartphone application scanner and a time-lapse camera...
2017: Plant Methods
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