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https://www.readbyqxmd.com/read/29341502/advances-in-intravesical-therapy-for-bladder-pain-syndrome-bps-interstitial-cystitis-ic
#1
REVIEW
En Meng, Yu-Chao Hsu, Yao-Chi Chuang
Bladder pain syndrome (BPS)/interstitial cystitis (IC) is a chronic symptom complex that may cause bothersome storage symptoms and pain or discomfort of the bladder, adversely affecting a patient's quality of life. The etiology of IC/BPS remains unclear, and its cause may be multifactorial. Diagnosis of IC/BPS is based on clinical features, and the possibility of other conditions must be ruled out first. Although no definitive treatment is currently available for IC/BPS, various intravesical therapies are used for IC/BPS, including heparin, hyaluronic acid, chondroitin sulfate, pentosan polysulfate, dimethylsulfoxide, liposomes, and botulinum onabotulinumtoxinA (BoNT-A)...
January 2018: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/29340877/brief-report-subjective-social-mobility-and-depressive-symptoms-in-syrian-refugees-to-germany
#2
Frank Euteneuer, Sarina J Schäfer
Previous findings indicate that refugees are at increased risk for mental health problems. In addition to stressful pre-migration experiences, post-migration factors may contribute to poor mental health outcomes. Among immigrants to the United States, downward mobility in subjective social status (SSS) was associated with depression, corroborating the potentially detrimental mental health consequences of a decline in one's perceived social position. The present study examined whether downward mobility in SSS among male refugees from Syria to Germany is associated with depression...
January 16, 2018: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29340261/medical-support-with-acupuncture-and-massage-therapies-for-disaster-victims
#3
Masataka Miwa, Shin Takayama, Soichiro Kaneko
Background: After the Great East Japan Earthquake and Tsunami Disaster (GEJED) and Joso City Flood (JCF), a number of people were relocated to evacuation centers. In situations following a large-scale disaster, acupuncture can be applied for various health problems in evacuation centers. In this study, we report the medical support operation for evacuees with acupuncture and massage therapy (AP/MT) and its effectiveness. In addition, we propose an experience-based guideline for AP/MT in such situations...
January 2018: Journal of General and Family Medicine
https://www.readbyqxmd.com/read/29339175/primary-thymic-adenocarcinomas-a-clinicopathological-and-immunohistochemical-study-of-16-cases-with-emphasis-on-the-morphological-spectrum-of-differentiation
#4
Neda Kalhor, Cesar A Moran
Sixteen cases of primary thymic adenocarcinoma are presented. The patients are 9 men and 7 women between the ages of 22 and 68 years (average: 45 years) who presented with non-specific symptoms including cough, chest pain, and dyspnea. Diagnostic imaging revealed the presence of an anterior mediastinal mass, which was surgically removed in all of the patients. Histologically, none of the tumors was encapsulated and showed different growth patterns including mucinous, non-mucinous, and papillary features. The majority of cases showed mixed growth pattern and the tumor was limited to the mediastinum with only a few cases extending to lymph nodes or pericardium...
January 12, 2018: Human Pathology
https://www.readbyqxmd.com/read/29338982/involvement-of-peripheral-alpha2a-adrenoceptor-in-the-acceleration-of-gastrointestinal-transit-and-abdominal-visceral-pain-induced-by-intermittent-deprivation-of-rem-sleep
#5
Fukie Yaoita, Masamichi Muto, Hiroki Murakami, Shiori Endo, Mifuyu Kozawa, Masahiro Tsuchiya, Takeshi Tadano, Koichi Tan-No
Many studies have associated sleep alterations with the severity of irritable bowel syndrome (IBS) symptoms, but the direct pathophysiological relationship has not been clarified. In addition, alterations in noradrenergic signaling have been implicated in the pathophysiology of IBS, and alpha2-adrenoceptors are potential treatment targets. We have previously shown that acceleration of gastrointestinal transit (GIT) elicited by intermittent rapid eye movement (REM) sleep deprivation stress may fulfill the profile of a model of IBS...
January 12, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29338968/an-alternative-tool-for-triaging-patients-with-possible-acute-coronary-symptoms-before-admission-to-a-chest-pain-unit
#6
Kuang-Chau Tsai, Ray F Lin, Chieh Lee, Ai-Hsien Li
OBJECTIVE: This study aimed to develop a triage tool to more effectively triage possible ACS patients presenting to the emergency department (ED) before admission to a protocol-driven chest pain unit (CPU). METHODS: Seven hundred ninety-three clinical cases, randomly selected from 7962 possible ACS cases, were used to develop and test an ACS triage model using cluster analysis and stepwise logistic regression. RESULTS: The ACS triage model, logit (suspected ACS patient)=-5...
December 13, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29338831/diagnosis-and-treatment-of-acute-intermittent-porphyria
#7
Jie Bai, Zhi Hong Wang
Acute intermittent porphyria (AIP) is a metabolic disease caused by hepatic deficiency of hydroxymethylbilane synthase. Its clinical manifestations include acute abdominal pain,neuropsychological abnormalities,and red urine. Due to its low incidence and varied clinical symptoms,the rates of misdiagnosis and mistreatment were particularly high. Biochemical testing and gene detection contribute to diagnosis. Management strategies include intravenous administration of human haemin,carbohydrate loading and symptomatic treatment...
December 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/29338493/challenges-of-peroral-endoscopic-myotomy-in-the-treatment-of-distal-esophageal-spasm
#8
Fraukje Anna-Marie Ponds, André J P M Smout, Paul Fockens, Albert J Bredenoord
OBJECTIVE: Distal esophageal spasm (DES) is a rare motility disorder characterized by premature and rapidly propagated contractions of the distal esophagus. Treatment options are limited and often poorly effective. Peroral endoscopic myotomy (POEM) seems an effective and attractive new treatment option for DES. In this case report we describe some of the difficulties that could arise. MATERIALS AND METHODS: A 84-year old man with therapy-refractory DES and complaints of severe dysphagia and chest pain underwent a POEM procedure under general anesthesia...
January 17, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29338163/kounis-syndrome-induced-by-oral-intake-of-diclofenac-potassium
#9
Harun Gunes, Feruza Turan Sonmez, Ayhan Saritas, Yasin Koksal
An acute coronary syndrome (ACS) occurring during the course of an allergic reaction is called Kounis syndrome (KS). The second case of KS induced by diclofenac potassium (DP) is presented in this report. A 67-year-old man was brought to our emergency department with the possible diagnosis of anaphylactic shock by the ambulance staff. It emerged that widespread erythema and pruritus developed after taking DP. Then, he lost consciousness. Diffuse urticarial lesions were detected on physical examination at the emergency department...
December 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/29337836/fever-as-a-presenting-symptom-in-children-evaluated-for-ileocolic-intussusception-the-experience-of-a-large-tertiary-care-pediatric-hospital
#10
Hila Levinson, Ayelet Rimon, Dennis Scolnik, Gil Amarilyio, Miguel Glatstein
BACKGROUND: Intussusception is the most common cause of intestinal obstruction in young children, and delayed diagnosis may lead to bowel perforation. The objective of this study was to determine the prevalence of fever in patients with ileocolic intussusception and to determine its utility as a predictive symptom. METHODS: This was a 3-year retrospective study, at a tertiary care center, of children aged 1 month to 6 years, presenting with possible intussusception...
January 15, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29337168/aggressive-resection-of-congenital-lumbosacral-lipomas-in-adults-indications-techniques-and-outcomes-in-122-patients
#11
S C Bai, B Z Tao, L K Wang, X G Yu, B N Xu, A J Shang
OBJECTIVE: The authors reviewed the treatment of adult patients with congenital intraspinal lipomas with total/near-total resection and discussed their preoperative characteristics, prognostic factors and surgical outcomes. METHODS: Medical records of 122 adult patients with congenital lumbosacral lipomas undergoing total/near-total resection were systematically analyzed. The cohort was subdivided into three groups depending on symptom onset age: Group 1 (≤5 years, n = 40), Group 2 (>5 years but <18 years, n = 33), and Group 3 (>18 years, n = 49)...
January 11, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29337024/moderators-of-treatment-outcomes-following-telehealth-self-management-and-education-in-adults-with-multiple-sclerosis-a-secondary-analysis-of-a-randomized-controlled-trial
#12
Dawn M Ehde, Anne Arewasikporn, Kevin N Alschuler, Abbey J Hughes, Aaron P Turner
OBJECTIVE: To examine moderators of treatment effects in a randomized controlled trial comparing a telehealth self-management intervention to a telehealth MS education intervention for fatigue, pain, and mood in adults with multiple sclerosis (MS). DESIGN: Secondary analysis of a single-blind randomized controlled trial. SETTING: community. PARTICIPANTS: Adults with MS and chronic fatigue, chronic pain, and/or moderate depressive symptoms (N=163) recruited from across the United States...
January 11, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29336927/efficacy-and-safety-of-sacral-and-percutaneous-tibial-neuromodulation-in-non-neurogenic-lower-urinary-tract-dysfunction-and-chronic-pelvic-pain-a-systematic-review-of-the-literature
#13
REVIEW
Manuela Tutolo, Enrico Ammirati, John Heesakkers, Thomas M Kessler, Kenneth M Peters, Tina Rashid, Karl-Dietrich Sievert, Michele Spinelli, Giacomo Novara, Frank Van der Aa, Dirk De Ridder
CONTEXT: Neuromodulation is considered in patients with non-neurogenic lower urinary tract dysfunction (LUTD) not responsive to conservative treatment. OBJECTIVE: To systematically review the available studies on efficacy and safety of sacral neuromodulation (SNM) and percutaneous tibial nerve stimulation (PTNS) in non-neurogenic LUTDs not responsive to conservative treatments. EVIDENCE ACQUISITION: A literature research was conducted in PubMed/Medline and Scopus, restricted to articles in English, published between January 1998 and June 2017, with at least 20 patients and 6 mo of follow-up...
January 11, 2018: European Urology
https://www.readbyqxmd.com/read/29336878/healing-of-periapical-lesions-after-endodontic-treatment-with-the-gentlewave-procedure-a-prospective-multicenter-clinical-study
#14
Asgeir Sigurdsson, Randy W Garland, Khang T Le, Shahriar A Rassoulian
INTRODUCTION: This report includes outcomes for a group of patients with significant periapical lesions who were treated and evaluated in two single-arm, multicenter, prospective, nonsignificant risk clinical studies. METHODS: Forty-five teeth were from 45 patients who met the inclusion criteria and consented for the clinical studies and were diagnosed with periapical lesions with periapical index score ≥3. Patients were treated with a standardized treatment protocol including instrumentation to an apical diameter of #20 without orifice enlargement, the GentleWave Procedure, and warm vertical obturation...
January 12, 2018: Journal of Endodontics
https://www.readbyqxmd.com/read/29336283/headaches-and-facial-pain-in-rhinology
#15
Asitha D L Jayawardena, Rakesh Chandra
"Sinus headache" is a common chief complaint that often leads patients to an otolaryngologist's office. Because facial pain may or may not be sinogenic in origin, the otolaryngologist should be equipped to evaluate and treat or to appropriately refer these patients. Analysis of current data indicates that the majority of patients who present with sinus headaches actually have migraines. Furthermore, the downstream effect of the cytokine cascade initiated in migraine physiology can cause rhinologic symptoms, including rhinorrhea, congestion, and lacrimation, which may also confound diagnosis...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29335748/hydrogel-implant-is-as-effective-as-osteochondral-autologous-transplantation-for-treating-focal-cartilage-knee-injury-in-24%C3%A2-months
#16
Antonio Altenor Bessa de Queiroz, Pedro Debieux, Joicemar Amaro, Mario Ferretti, Moises Cohen
PURPOSE: The treatment approach for a patient with knee joint focal cartilage lesion is a difficult decision. To date, there has been no randomized clinical trial involving Hydrogel (Cartiva™). This study evaluated and compared the results of a hydrogel implant (Cartiva™) with autologous osteochondral transplantation (AOT) for treating knee joint focal cartilage lesions. METHODS: Thirty-eight symptomatic patients, with a focal cartilage lesion of Outerbridge grades III or IV, were randomized into one of two groups according to the inclusion and exclusion criteria...
January 15, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29335229/ciliated-cyst-of-the-gallbladder-a-new-case-and-literature-review
#17
Triki Wissem, Baraket Oussema, Itami Ahmed, Baccar Abdelmajid, Marzouk Ines, Bouchoucha Sami
INTRODUCTION: The ciliated cyst is a rare anomaly that develops from the anterior primitive intestine. Its localization is essentially supra diaphragmatic. It's localization in the gallbladder is very uncommon. CASE REPORT: We report the first case in Tunisia of a ciliated cyst of the gallbladder in a 34 years old woman who was operated for a gallbladder stone and in whom the discovery of a cystic mass attached to the neck of the gallbladder was preoperatively. The pathologic study did conclude to a ciliated cyst...
December 21, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29334974/prevalence-of-dysmenorrhea-and-predictors-of-its-pain-intensity-among-palestinian-female-university-students
#18
Heba A Abu Helwa, Areen A Mitaeb, Suha Al-Hamshri, Waleed M Sweileh
BACKGROUND: Few studies on gynaecological problems of young females in Arab countries were published. The aim of this study was to determine the prevalence of dysmenorrhea and predictors of its pain among university students in Palestine. METHODS: A cross - sectional study was carried out on a randomly selected sample of An-Najah National University female students. A pre-designed questionnaire, which included questions regarding menstrual cycle, pain during menstruation, life style, nutritional habits, and symptoms associated with menstrual pain, was used...
January 15, 2018: BMC Women's Health
https://www.readbyqxmd.com/read/29334798/vulvar-vestibular-effects-of-ospemifene-a-pilot-study
#19
Filippo Murina, Stefania Di Francesco, Silvia Oneda
The study aimed to assess the effects of ospemifene on vulvar vestibule in postmenopausal women with vulvar pain and dyspareunia. Fifty-five postmenopausal women used oral ospemifene 60 mg/d for 60 d. Symptoms of dryness, burning, and dyspareunia were evaluated on a 10 cm visual analog scale. Visual examination of the vulvar vestibule was also conducted. Patients also underwent current perception threshold (CPT) testing obtained from the vulvar vestibule. Fifty-five patients (94.6%) completed the treatment...
January 15, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29334760/polymorphisms-in-estrogen-synthesis-genes-and-symptom-clusters-during-the-menopausal-transition-and-early-postmenopause-observations-from-the-seattle-midlife-women-s-health-study
#20
Nancy Fugate Woods, Lori A Cray, Ellen Sullivan Mitchell, Fred Farrin, Jerald Herting
During the menopausal transition and early postmenopause, participants in the Seattle Midlife Women's Health Study (SMWHS) experienced one of the three symptom severity clusters identified through latent class analysis: severe hot flashes with moderate sleep, mood, cognitive, and pain symptoms (high-severity hot flash); low-severity hot flashes with moderate levels of all other symptom groups (moderate severity); and low levels of all symptom groups (low severity). In an effort to determine whether gene polymorphisms were associated with these symptom severity classes, we tested associations between gene polymorphisms in the estrogen synthesis pathways (cytochrome P450 19 [CYP 19] and 17 beta hydroxysteroid dehydrogenase [ 17HSDB1]) and the three symptom severity clusters...
January 1, 2018: Biological Research for Nursing
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