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https://www.readbyqxmd.com/read/28634897/the-effect-of-surgical-technique-and-spacer-texture-on-bone-regeneration-a-caprine-study-using-the-masquelet-technique
#1
Viviane Luangphakdy, G Elizabeth Pluhar, Nicolás S Piuzzi, Jean-Claude D'Alleyrand, Cathy S Carlson, Joan E Bechtold, Jonathan Forsberg, George F Muschler
BACKGROUND: The Masquelet-induced-membrane technique is a commonly used method for treating segmental bone defects. However, there are no established clinical standards for management of the induced membrane before grafting. QUESTIONS/PURPOSES: Two clinically based theories were tested in a chronic caprine tibial defect model: (1) a textured spacer that increases the induced-membrane surface area will increase bone regeneration; and (2) surgical scraping to remove a thin tissue layer of the inner induced-membrane surface will enhance bone formation...
June 20, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28625735/analgesic-and-physiological-effect-of-electroacupuncture-combined-with-epidural-lidocaine-in-goats
#2
Lu-Ying Cui, Ni-Ni Guo, Yu-Lin Li, Meng Li, Ming-Xing Ding
OBJECTIVE: To investigate physiological and antinociceptive effects of electroacupuncture (EA) with lidocaine epidural nerve block in goats. STUDY DESIGN: Prospective experimental trial. ANIMALS: Forty-eight hybrid male goats weighing 27 ± 2 kg. METHODS: The goats were randomly assigned to six groups: L2.2, epidural lidocaine (2.2 mg kg(-1)); L4.4, epidural lidocaine (4.4 mg kg(-1)); EA; EA-L1.1, EA with epidural lidocaine (1...
January 12, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28622494/laryngeal-neuropathy-in-adult-goats-with-copper-deficiency
#3
R F A Sousa, V M Almeida, J E Neto, C W A Nascimento, G X Medeiros, R M T Medeiros, F Riet-Correa, F S Mendonça
The aim of this study was to elucidate the cause of a neurological syndrome characterized by stridor in adult goats with clinical signs of copper deficiency. The main clinical signs consisted of apathy, emaciation, pale mucous membranes, mucous nasal discharge, dyspnea, severe achromotrichia, diffuse alopecia, torpor, ataxia, and stridor. When the goats were forced to move, the stridor increased. In a herd of 194 Toggenburg goats, 10 adult goats with clinical signs of copper deficiency were removed from the herd and divided into 2 groups: group 1, which consisted of 4 nannies and 1 buck with stridor, and group 2, which consisted of 4 nannies and 1 buck without stridor...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28603109/phytochemical-and-biological-assessments-on-lipidium-meyenii-maca-and-epimidium-sagittatum-horny-goat-weed
#4
Mahmood Qureshi, - Mehjabeen, - Noorjahan, Shafi Muhammad, Faheem Ahmed Siddiqui, Iftikhar Baig, Mansoor Ahmad
The effects of Lipidium meyenii (maca, LM) and Epimidium sagittatum (horny goat weed, ES) have been investigated due to their involvement in fertilization. Both of the drugs showed good results before, during and after fertilization in male and female mice. The results revealed that the crude extract of Lipidium meyenii caused a significant decrease in the no. of writhes at 300 and 500mg/kg (p<0.05) as compare to control, Epimidium sagittatum and standard drug. The gross behavioral, open field, exploratory behaviour, forced swimming test for stress, diuretic activity, chronic toxicity with the effect on reproduction of both male and female and change in body weight were also studied...
January 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28597925/validation-of-a-procedure-to-quantify-oxolinic-acid-danofloxacin-ciprofloxacin-and-enrofloxacin-in-selected-meats-by-micellar-liquid-chromatography-according-to-eu-commission-decision-2002-657-ec
#5
Juan Peris-Vicente, Khaled Tayeb-Cherif, Samuel Carda-Broch, Josep Esteve-Romero
The suitability of an analytical method to determine oxolinic acid, danofloxacin, ciprofloxacin and enrofloxacin in edible tissues, based on micellar liquid chromatography coupled with fluorescence detection, to be applied in chicken, turkey, duck, lamb, goat, rabbit and horse muscle, is described. The method was fully matrix-matched in-lab revalidated, for each antimicrobial drug and meat, following the guidelines of the EU Commission Decision 2002/657/EC. The permitted limits were the maximum residue limits stated by the EU Commission Regulation 37/2010...
June 9, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28579027/molecular-detection-of-toxoplasma-gondii-in-the-slaughter-sheep-and-goats-from-north-india
#6
Deepali Kalambhe, J P S Gill, Balbir Bagicha Singh
Toxoplasma gondii is an obligate intracellular parasite that infects almost all the warm blooded animals, including human beings. The disease usually remains asymptomatic but is a serious concern for pregnant women, developing foetus and immuno-compromised individuals. We collected 400 cardiac/skeletal muscle tissue samples from slaughter sheep (177) and goat (223) intended for human consumption from Punjab, Uttar Pradesh and Chandigarh states/union territory in North India. The samples were pepsin-HCl digested and DNA was extracted from all the digested samples...
July 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28576552/poisoning-in-goats-by-the-monofluoracetate-containing-plant-palicourea-aeneofusca-rubiaceae
#7
Temístocles Soares de Oliveira Neto, Franklin Riet-Correa, Stephen T Lee, Daniel Cook, Francisca Maria Sousa Barbosa, José Ferreira da Silva Neto, Sara Vilar Dantas Simões, Ricardo Barbosa Lucena
The epidemiological, clinical and pathological aspects of a spontaneous outbreak of Palicourea aeneofusca poisoning in goats are reported. The main clinical signs were motor incoordination, generalized muscle tremors, broad-based posture, tachypnea, tachycardia, vocalization and respiratory distress. Two goats died 5 and 20 min after the observation of the first clinical signs. Another that was found recumbent died 80 h later. One goat with mild clinical signs recovered. Congestion and hemorrhages were observed macroscopically and histologically in most organs...
May 31, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28542844/the-inward-rectifier-current-inhibitor-pa-6-terminates-atrial-fibrillation-and-does-not-cause-ventricular-arrhythmias-in-dedicated-goat-and-dog-models
#8
Yuan Ji, Rosanne Varkevisser, Dragan Opacic, Alexandre Bossu, Marion Kuiper, Jet D M Beekman, Sihyung Yang, Azinwi Phina Khan, Dobromir Dobrev, Niels Voigt, Michael Zhuo Wang, Sander Verheule, Marc A Vos, Marcel A G Van der Heyden
BACKGROUND AND PURPOSE: Inward rectifier current (IK1 ) density increases in atrial fibrillation (AF), shortening effective refractory period and thus promotes atrial reentry. Pentamidine-Analogue 6 (PA-6) is a selective and potent IK1 inhibitor. We tested PA-6 for anti-AF efficacy and potential proarrhythmia, in established large animal models. EXPERIMENTAL APPROACH: PA-6 was applied i.v. in anaesthetized goats with rapid pacing induced AF and anaesthetized chronic AV block dogs...
May 24, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28539940/horizontal-and-vertical-distribution-of-heavy-metals-in-farm-produce-and-livestock-around-lead-contaminated-goldmine-in-dareta-and-abare-zamfara-state-northern-nigeria
#9
O E Orisakwe, O O Oladipo, G C Ajaezi, N A Udowelle
Background. Hitherto studies in response to the June 2010 lead poisoning, Zamfara State, Nigeria, have focused on clinical interventions without information on livestock and other metals. Objective. This study has investigated the distribution of heavy metals in farm produce and livestock around lead-contaminated goldmine in Dareta and Abare, Zamfara State, Nigeria. Methods. Vegetables, soil, water, blood, and different meat samples were harvested from goat, sheep, cattle, and chicken from Dareta, Abare, and Gusau communities...
2017: Journal of Environmental and Public Health
https://www.readbyqxmd.com/read/28462799/a-novel-physiological-testing-device-to-study-knee-biomechanics-in-vitro
#10
Fabian van de Bunt, Kaj S Emanuel, Thomas Wijffels, Peter N Kooren, Idsart Kingma, Theodoor H Smit
BACKGROUND: To properly study knee kinetics, kinematics and the effects of injury and surgical treatment in vitro, the knee should be constrained as little as possible, while imposing physiological loads. A novel dynamic biomechanical knee system (BKS) is presented here. The aim of this study was to test the feasibility and reproducibility of the system and demonstrate its features with an Anterior Cruciate Ligament (ACL) lesion model. METHODS: Six goat knees were used in the current study...
April 25, 2017: Knee
https://www.readbyqxmd.com/read/28458227/a-sensitive-and-validated-immunomagnetic-bead-based-enzyme-linked-immunosorbent-assay-for-analyzing-total-t-2-free-and-modified-toxins-in-shrimp-tissues
#11
Qi Deng, Mei Qiu, Yaling Wang, Pengli Lv, Chaojin Wu, Lijun Sun, Riying Ye, Defeng Xu, Ying Liu, Ravi Gooneratne
Accurate analyses of total T-2 (free and modified) in aquatic organisms including shrimp are important as the hazard caused by T-2 has been caught increasing attention. Therefore, acurate analysis of free T-2 especially of modified T-2 in shrimp tissues is important. A rapid, sensitive, and validated method for quantitative determination of free T-2 and modified T-2 toxin was developed using immunomagnetic-bead based enzyme-linked immunosorbent assay (IMB-ELISA). Super paramagnetic particles with a carboxyl group activated by an ester method coupled with envelope antigen 3- acetylneosolaniol- hemisuccinate - ovalbumin (3-Ac-NEOS-HS-OVA) was used to form immunomagnetic beads which could bind to T-2 skeletal structure antibodies...
August 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28446002/effects-of-fungal-lentinussajor-caju-treated-oil-palm-frond-on-performance-and-carcass-characteristics-in-finishing-goats
#12
Pin Chanjula, Vasun Petcharat, Anusorn Cherdthong
OBJECTIVE: This experiment was conducted to investigate the effects of fungal treated oil palm fronds (FTOPF) on performance, carcass traits, meat quality, and muscle chemical composition. METHODS: Eighteen growing crossbred male goats (Thai Native×Anglo Nubian) with 18.7±2.0 kg of initial body weight (BW) were stratified and blocked by BW in a randomized complete block design. Three diets containing 30% of oil palm fronds (OPF) either untreated (UOPF) or treated with Lentinussajor-caju (FTOPF) with or without urea (FTOPFU) were used as roughage sources in total mixed rations (TMRs)...
June 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28358646/short-hairpin-mediated-myostatin-knockdown-resulted-in-altered-expression-of-myogenic-regulatory-factors-with-enhanced-myoblast-proliferation-in-fetal-myoblast-cells-of-goats
#13
Rohit Kumar, Satyendra Pal Singh, Abhijit Mitra
Myostatin (MSTN) is a well-known negative regulator of skeletal muscle development. Reduced expression due to natural mutations in the coding region and knockout as well as knockdown of MSTN results in an increase in the muscle mass. In the present study, we demonstrated as high as 60 and 52% downregulation (p < 0.01) of MSTN mRNA and protein in the primary fetal myoblast cells of goats using synthetic shRNAs (n = 3), without any interferon response. We, for the first time, evaluated the effect of MSTN knockdown on the expression of MRFs (namely, MyoD, Myf5), follistatin (FST), and IGFs (IGF-1 & IGF-2) in goat myoblast cells...
March 30, 2017: Animal Biotechnology
https://www.readbyqxmd.com/read/28288753/proteomic-analysis-of-taenia-ovis-metacestodes-by-high-performance-liquid-chromatography-coupled-tandem-mass-spectrometry
#14
Yadong Zheng
Taenia ovis metacestodes reside in the muscle of sheep and goats, and may cause great economic loss due to condemnation of carcasses if not effectively controlled. Although advances have been made in the control of T. ovis infection, our knowledge of T. ovis biology is limited. Herein the protein profiling of T. ovis metacestodes was determined by liquid chromatography-linked tandem mass spectrometry. A total of 966 proteins were identified and 25.1% (188/748) were annotated to be associated with metabolic pathways...
March 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28283013/-molecular-characterization-of-echinococcus-granulosus-isolates-obtained-from-different-hosts
#15
Emrah Erdoğan, Bora Özkan, Fatih Mutlu, Serkan Karaca, İzzet Şahin
Echinococcus granulosus is a parasite that can be seen throughout the world. So far, five species of genus Echinococcus have been identified as parasite in people: E.granulosus, E.multilocularis, E.vogeli, E.oligarthrus, E.shiquicus. Larval (metacestod) form of parasite settles in internal organs of hoofed animals (cattle, goats, pigs, horses, sheep, etc.) and human; the adult form is found in small intestine of final host, canine. Disease caused by parasite called as "Cystic echinococcosis" (CE) is an important health problem and causes economic losses in many countries including our country that livestock is common...
January 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28176534/effects-of-piroxicam-on-tissue-distribution-of-sulfadimidine-in-west-african-dwarf-male-and-female-goats
#16
E I Akogwu, S A Saganuwan, P A Onyeyili
Cases of Stevens-Johnson syndrome have been increasingly reported in Nigeria by individuals who consumed meat products of animals especially goats injected sulfonamides. Hence, tissue distribution and residues of intramuscular sulfadimidine were studied in West African Dwarf (WAD) goats. Twenty goats divided into two groups of 10 each (five males; five females) weighing 10.4 ± 1.63 kg were administered intramuscular sulfadimidine (100 mg/kg body weight), and the second group was coadministered 5 mg/kg of piroxicam via right and left thigh muscle, respectively...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28115030/effects-of-farm-management-practices-and-transport-duration-on-stress-response-and-meat-quality-traits-of-suckling-goat-kids
#17
M J Alcalde, M D Suárez, E Rodero, R Álvarez, M I Sáez, T F Martínez
Studies aimed to assess up to what extent farming and transport previous to slaughtering might affect physiology and meat quality in young goat kids are needed, with the ultimate purpose of promoting practices that minimize stress in these animals. In this regard the effects of on-farm management and transport duration on some physiological responses and meat quality parameters in goat kids were assessed. Two farms representing 'high' and 'low' welfare-friendly management practices were selected. In total, 32 suckling kids were withdrawn from each farm, transported by road for 2 or 6 h, and then slaughtered...
January 24, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28002930/the-effects-of-grazing-system-and-floor-type-on-blood-biochemistry-growth-body-condition-score-and-carcass-characteristics-of-nguni-goats
#18
Allen Tapiwa Chikwanda, Voster Muchenje
The study was conducted to determine the effects of grazing management (tethering vs herding) and floor type (earth vs slatted) on the concentrations of blood metabolites, activity of creatine kinase, body weight (BW), body condition score (BCS) and carcass characteristics of castrated Nguni goats. Forty eight, 7 month old goats were randomly allocated to herding (H) and tethering (T) treatments and accommodated in pens with slatted (SF) and earth (EF) floors. The T and H treatments were imposed daily, for 5 months, between 0800- 1300 hours followed by penning...
December 17, 2016: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/27891064/proteomic-based-approach-for-characterizing-4-hydroxy-2-nonenal-induced-oxidation-of-buffalo-bubalus-bubalis-and-goat-capra-hircus-meat-myoglobins
#19
Naveena B Maheswarappa, K Usha Rani, Y Praveen Kumar, Vinayak V Kulkarni, Srikanth Rapole
BACKGROUND: Myoglobin (Mb) is a sarcoplasmic heme protein primarily responsible for meat color and its chemistry is species specific. 4-hydroxy-2-nonenal (HNE) is a cytotoxic lipid derived aldehyde detected in meat and was reported to covalently adduct with nucleophilic histidine residues of Mb and predispose it to greater oxidation. However, no literature is available on characterization of lipid oxidation induced oxidation of Indian water buffalo (Bubalus bubalis) and goat (Capra hircus) myoglobins...
2016: Proteome Science
https://www.readbyqxmd.com/read/27870918/time-dependent-impact-of-irreversible-electroporation-on-pancreas-liver-blood-vessels-and-nerves-a-systematic-review-of-experimental-studies
#20
REVIEW
J A Vogel, E van Veldhuisen, P Agnass, J Crezee, F Dijk, J Verheij, T M van Gulik, M R Meijerink, L G Vroomen, K P van Lienden, M G Besselink
INTRODUCTION: Irreversible electroporation (IRE) is a novel ablation technique in the treatment of unresectable cancer. The non-thermal mechanism is thought to cause mostly apoptosis compared to necrosis in thermal techniques. Both in experimental and clinical studies, a waiting time between ablation and tissue or imaging analysis to allow for cell death through apoptosis, is often reported. However, the dynamics of the IRE effect over time remain unknown. Therefore, this study aims to summarize these effects in relation to the time between treatment and evaluation...
2016: PloS One
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