Azzania Fibriani, Audrey Angelina Putri Taharuddin, Nicholas Yamahoki, Rebecca Stephanie, Jessica Laurelia, Dian Fitria Agustiyanti, Popi Hadi Wisnuwardhani, Marissa Angelina, Yana Rubiyana, Ratih Asmana Ningrum, Andri Wardiana, Desriani Desriani, Ferry Iskandar, Fitri Aulia Permatasari, Ernawati Arifin Giri-Rachman
BACKGROUND: Since effective antiviral drugs for COVID-19 are still limited in number, the exploration of compounds that have antiviral activity against SARS-CoV-2 is in high demand. Porphyrin is potentially developed as a COVID-19 antiviral drug. However, its low solubility in water restricts its clinical application. Reconstruction of porphyrin into carbon dots is expected to possess better solubility and bioavailability as well as lower biotoxicity. METHODS AND RESULTS: In this study, we investigated the antiviral activity of porphyrin and porphyrin-derived carbon dots against SARS-CoV-2...
October 6, 2023: Journal, Genetic Engineering & Biotechnology