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https://www.readbyqxmd.com/read/29225839/a-case-of-empyema-and-septic-arthritis-due-to-nocardia-farcinica
#1
Takashi Ishiguro, Hiroaki Yoshioka, Shoko Kawai, Shin-Ichi Katsumata, Tohru Gonoi, Noboru Takayanagi
Septic arthritis due to Nocardia sp. should be suspected when a patient with risk factors such as pneumoconiosis or diabetes mellitus develops joint symptoms, especially if the patient has had nocardiosis in other sites.
December 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29218573/dual-neutralization-of-tnfr-2-and-mmp-2-regulates-the-severity-of-s-aureus-induced-septic-arthritis-correlating-alteration-in-the-level-of-interferon-gamma-and-interleukin-10-in-terms-of-tnfr2-blocking
#2
Sahin Sultana, Rajen Dey, Biswadev Bishayi
Severity of S. aureus septic arthritis is correlated to prolonged inflammation by inflammatory cytokines like TNF-α, IL-1β, and IL-6 even after successful elimination of bacteria. Role of TNF-α via TNFR2 is not well established in this aspect. IFN-γ induces TNF-α release from the macrophages augmenting the inflammatory arthritis. IL-10 modulates the levels of pro-inflammatory cytokines promoting resolution of inflammation. TNF-α-TNFR2 signaling upregulates both of these cytokines. Higher level of MMP-2 induction by inflammatory cytokines during arthritis promotes tissue destruction...
December 7, 2017: Immunologic Research
https://www.readbyqxmd.com/read/29216705/-functional-results-of-open-wedge-osteotomies-in-lower-limb-angular-deformities-in-teenagers
#3
C Orellana-Reta, L A Valdez-Jiménez
OBJECTIVE: The aim of this study was to evaluate the functional and radiographic results of adolescent patients with angular deformities of the pelvic limbs treated with an open wedge osteotomy system. MATERIAL AND METHODS: Observational, prospective, analytical and cross-sectional study of patients with angular deformity of the pelvic limbs treated with an open wedge osteotomy. We made a radiographic evaluation of the femorotibial angle, MAD angle, lower limb discrepancy, and pre- and postoperative degrees of the rotational center of deformity (CORA), as well as a telephone survey of the postoperative functional evaluation IKDC 2000...
May 2017: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/29215382/initial-treatment-in-septic-arthritis-medical-versus-surgical-approach-an-8-year-single-center-in-spain-experience
#4
Bryan Josué Flores-Robles, Mercedes Jiménez Palop, Abel Alejandro Sanabria Sanchinel, Robert Francis Andrus, Ana Royuela Vicente, Marta Isabel Sanz Pérez, María Espinosa Malpartida, Consuelo Ramos Giráldez, Carolina Merino Argumanez, Luis Fernando Villa Alcázar, José Luis Andréu Sánchez, Hildegarda Godoy Tundidor, José Campos Esteban, Jesús Sanz Sanz, Carmen Barbadillo Mateos, Carlos Isasi Zaragoza, Juan Mulero Mendoza
OBJECTIVE: The aim of this study was to compare the functional results of 2 different procedure types, medical or surgical, which are used in treating native joint septic arthritis. METHODS: In this retrospective cohort study, we reviewed clinical registries of patients admitted to a single third-level hospital with the diagnosis of septic arthritis during the period of January 1, 2008, to January 31, 2016. RESULTS: A total of 63 cases of septic arthritis were identified in which the initial approach for 49 patients was medical (arthrocentesis), whereas the initial approach for 14 patients was surgical (arthroscopy or arthrotomy)...
December 5, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29208200/-primary-septic-arthritis-is-a-rare-atypical-manifestation-of-invasive-meningococcal-disease
#5
Anne Katrine Bisgaard, Steen Kåre Fagerberg, Ulla Hjort
We present a case report of a 50-year-old man diagnosed with a primary septic arthritis with invasive Neisseria meningitidis serogroup W (MenW) clonal complex 11 identified with culture in blood and synovial fluid. The patient recovered from rapidly instituted relevant antibiotics and synovectomy, but there may be a risk of fatal delayed diagnosis and treatment by an atypical manifestation of invasive meningococcal disease. Invasive MenW disease has been increasing in recent years and has been described with atypical presentations...
November 27, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29207945/meningococcal-arthritis-and-myopericarditis-a-case-report
#6
Lloyd Steele, Katie Bechman, Eoghan De Barra, Charles Mackworth-Young
BACKGROUND: We report the first adult case of Neisseria meningitidis W-135 presenting with meningococcal arthritis and myopericarditis concomitantly, without other classical features of meningococcal disease. CASE PRESENTATION: A 67-year-old Caucasian man presented with acute-onset polyarthralgia, myalgia, and fever. On examination he had polyarticular synovitis. An electrocardiogram (ECG) demonstrated ST-elevation in leads I, II, III, aVF, and V2-V6 without reciprocal depression, and a high-sensitivity troponin level was significantly elevated...
December 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29205875/a-case-report-of-basic-calcium-phosphate-mimicking-septic-arthritis
#7
Queenie Luu, Siroos Nasibi, Praneal Sharma, Andrew Bonura, David Massasso
We report a case of a 53-year-old man who presented with a diagnostic dilemma mimicking septic arthritis. It is important to consider the diagnosis of calcific peri-arthritis clinically and recognize the hallmarks on radiograph and magnetic resonance imaging as this disease process resolves completely with conservative management like in our patient, and does not require operative intervention.
December 4, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29199508/wrist-inflammation-a-retrospective-comparison-between-septic-and-non-septic-arthritis
#8
Gavrielle Kang, Mabel Q H Leow, Shian-Chao Tay
This study aims to identify differences in demographics, clinical and laboratory data between wrist septic arthritis and non-septic arthritis in patients admitted for wrist inflammation. A retrospective review of inpatients from May 2012 to April 2015 was conducted. Seventy-seven patients were included. Non-septic arthritis patients were more likely to have chronic kidney disease, pre-existing gout, or both. All septic arthritis patients had normal serum uric acid levels, and two or more raised inflammatory markers (white cell count, C-reactive protein, erythrocyte sedimentation rate)...
January 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29189591/luc-s-abscess-and-temporomandibular-joint-septic-arthritis-two-rare-sequelae-of-acute-otitis-media
#9
Carmelle Tsai, Jennifer Deramo, Xiaofan Shen, Kathleen Vandiver, Vineeta Mittal
A 5-year-old previously healthy child presented with right-sided otalgia, right facial and temporal swelling, and right jaw pain in the setting of 6 days of low-grade fever. The child had no trauma, vomiting, or prior dental treatments. On physical examination, the patient had facial swelling, erythema, and tenderness over the right temporal region along with trismus, as well as pain on palpation of the right temporomandibular joint (TMJ). A computed tomography scan revealed otitis media, Luc's abscess, and TMJ septic arthritis requiring surgical drainage and intravenous antibiotics...
November 20, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29187561/a-real-pain-diagnostic-quandaries-and-septic-arthritis
#10
Cristina Costales, Susan M Butler-Wu
Rapid diagnosis and treatment of an infected joint is paramount in preserving orthopedic function. Here, we present a brief review of the many challenges associated with the diagnosis of both septic arthritis and prosthetic joint infections. We will also discuss the many laboratory tests currently available to aid in accurate diagnosis of joint infection as well as emerging diagnostics that may have future utility in the diagnosis of these challenging clinical entities.
November 29, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29181204/a-case-of-invasive-pneumococcal-infection-with-septic-shock-and-rare-complications
#11
John R Woytanowski, Nausheen Hakim, Caytlin Deering, Sara Schultz
Invasive pneumococcus is a serious illness with potentially devastating outcomes. A 64-year-old female with a medical history of psoriatic arthritis and diabetes was transferred from an outside hospital for ventilator dependent respiratory failure and altered mental status. She initially presented with worsening back pain and was found to have leukocytosis with bandemia and acute renal failure but she was in septic shock upon arrival to our tertiary care center. Her blood cultures grew Streptococcus pneumoniae and MRI of the brain revealed pus within the posterior lateral ventricles and multiple infarcts...
2017: Case Reports in Critical Care
https://www.readbyqxmd.com/read/29168180/cxcr2-is-critical-for-bacterial-control-and-development-of-joint-damage-and-pain-in-staphylococcus-aureus-induced-septic-arthritis-in-mouse
#12
Daiane Boff, Vivian L S Oliveira, Celso M Queiroz Junior, Tarcília A Silva, Marcelo Allegretti, Waldiceu A Verri, Paul Proost, Mauro M Teixeira, Flavio A Amaral
Staphylococcus aureus is the main pathogen associated with septic arthritis. Upon infection, neutrophils are quickly recruited to the joint by different chemoattractants, especially CXCR1/2 binding chemokines. Although their excessive accumulation is associated with intense pain and permanent articular damage, neutrophils have an important function in controlling bacterial burden. This work aimed to study the role of CXCR2 in the control of infection, hypernociception and tissue damage in S. aureus-induced septic arthritis in mice...
November 22, 2017: European Journal of Immunology
https://www.readbyqxmd.com/read/29167605/clinical-outcomes-involving-patients-that-develop-septic-arthritis-with-methicillin-sensitive-staphylococcus-aureus-versus-methicillin-resistant-staphylococcus-aureus
#13
REVIEW
Kristen Combs, Kyle Cox
Septic Arthritis is an orthopedic emergency that requires prompt diagnosis and treatment. Staphylococcus aureus is the most common pathogen causing septic arthritis. This review seeks to describe clinical characteristics and outcomes associated with patients with methicillin-resistant (MRSA) vs. methicillin-sensitive staphylococcus aureus (MSSA) septic arthritis. The review showed that those infected with MRSA were older, had more chronic medical conditions, and higher values of inflammatory markers. MRSA septic arthritis was also associated with more complications, longer duration of antibiotics, and increased mortality...
March 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29164082/acute-septic-arthritis-of-the-knee-caused-by-kingella-kingae-in-a-5-year-old-cameroonian-boy
#14
Nawal El Houmami, Dimitri Ceroni, Karine Codjo Seignon, Jean-Christophe Pons, Cédric Lambert, Guillaume André Durand, Philippe Minodier, Léopold Lamah, Philippe Bidet, Jacques Schrenzel, Didier Raoult, Pierre-Edouard Fournier
Kingella kingae is an important cause of invasive infections in young children from Western countries. Although increasing reports indicate that this organism is the leading agent of bone and joint infections in early childhood, data on K. kingae infections from resource-limited settings are scarce, and none has yet been reported in Africa. We herein report the diagnostic and epidemiological investigations of the first case of K. kingae arthritis identified in a child from sub-Saharan Africa. A 5-year-old Cameroonian boy presented with a sudden painful limp which appeared in the course of a mild rhinopharyngitis...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29141929/septic-arthritis-of-knee-joint-due-to-parvimonas-micra
#15
Moni Roy, Ashish Kumar Roy, Sharjeel Ahmad
Parvimonas species are anaerobic, Gram-positive cocci that are a constituent of normal oral and gastrointestinal flora. We present a case of right knee joint septic arthritis due to Parvimonas micra in an immunocompromised patient. A 61-year-old male renal and pancreatic transplant recipient on immunosuppressive therapy was admitted to our hospital due to intense pain, joint swelling and inability to move his right knee over the past 9 months. After synovial fluid was drawn, cultures were positive for P. micra, an anaerobic pathogen that is part of the flora of the oral cavity...
November 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29138043/non-traumatic-limping-in-paediatric-emergencies-epidemiology-evaluation-and-results
#16
M I Lázaro Carreño, R Fraile Currius, A García Clemente
INTRODUCTION: Non-traumatic limping is a common reason for consultation in paediatric emergencies. Although transient synovitis of the hip (TS) is the most frequent diagnosis, there are cases of limping secondary to serious pathologies. The aim of this review is to describe the variables related to non-traumatic limp that come to the paediatric emergency department to establish the best management protocol, making the most of resources and speeding up emergency care. MATERIAL AND METHOD: A prospective study was conducted, selecting all children less than 15 years old who consulted aspaediatric emergencies for non-traumatic limping during the 2014...
November 11, 2017: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/29130010/spontaneous-bilateral-sternoclavicular-joint-septic-arthritis-and-lumbar-discitis-an-unusual-case-in-a-healthy-adult
#17
Georgios Mamarelis, Mohammad Zain Sohail, Athanasios Mamarelis, Hassan Fawi, Jehangir Mahaluxmivala
Introduction: Septic arthritis of the sternoclavicular (SC) joint is a rare condition. Typically, it presents in patients with risk of infection and is usually unilateral. In this report, we describe a case of spontaneous bilateral sternoclavicular joint infection of an otherwise healthy adult. Case Presentation: A 67-year-old man presented in our hospital complaining of 2-week history of neck and chest pain which was radiating to his shoulders bilaterally. Clinical examination revealed erythema and swelling of the sternoclavicular area...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/29127017/the-educational-opportunities-provided-by-a-pediatric-orthopedic-urgent-case-review-conference-keep-score-to-provide-a-better-experience
#18
Eric D Shirley, Radu Gheorghe, Kevin M Neal, Gary Kiebzak, Steven L Frick
OBJECTIVE: To evaluate the distribution of conditions presented at a case conference to assess resident educational exposure to acute pediatric orthopedic conditions. DESIGN: Retrospective review of emergency department and inpatient consultations presented at a daily pediatric orthopedic case conference over a 3-year period. Consultations were divided into 3-month resident rotation blocks for analysis. SETTING: Tertiary children's hospital in the southern United States which host residents from 2 orthopedic surgery residency programs...
November 7, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/29122433/anterior-cruciate-ligament-graft-removal-versus-retention-in-the-setting-of-septic-arthritis-after-reconstruction-a-systematic-review-and-expected-value-decision-analysis
#19
REVIEW
Nicholas Kusnezov, Emmanuel D Eisenstein, John C Dunn, Aaron J Wey, David R Peterson, Brian R Waterman
PURPOSE: To provide further guidance on the optimal decision between anterior cruciate ligament (ACL) graft removal versus retention in the setting of septic arthritis following reconstruction using an expected value decision analysis. METHODS: A systematic review and expected value decision analysis and sensitivity analyses were performed to quantify the clinical decision. A decision tree was created with 5 outcomes of interest: nonoperative complications, revision surgery, early reoperation, late reoperation, and "well...
November 6, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29115078/elderly-patients-exhibit-stronger-inflammatory-responses-during-gout-attacks
#20
Jae Hyun Lee, Ji Ae Yang, Kichul Shin, Ga Hye Lee, Won Woo Lee, Eun Young Lee, Yeong Wook Song, Eun Bong Lee, Jin Kyun Park
Gout attacks are often accompanied by systemic inflammatory response. The aim of the retrospective study was to compare gout patients in different age groups in terms of their clinical features at gout attacks. Patients, who were treated for gout attack in two tertiary medical centers between January 2000 and April 2014, were divided into young (≤ 50 years), middle-aged, and elderly (> 65 years) groups. Patients in three age groups were compared in terms of presence of fever (> 37.8°C), C-reactive protein (CRP) levels, and erythrocyte sedimentation ratio (ESR) at the gout attacks...
December 2017: Journal of Korean Medical Science
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