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https://www.readbyqxmd.com/read/29668139/-zoonotic-intestinal-nematodes-in-dogs-from-public-parks-in-yucat%C3%A3-n-m%C3%A3-xico
#1
Rodrigo Adán Medina-Pinto, Roger Iván Rodríguez-Vivas, Manuel Emilio Bolio-González
INTRODUCTION: Dogs represent a potential public health risk because of the natural transmission of zoonotic parasitic infections. OBJECTIVE: To estimate the frequency and to determine factors associated with the presence of intestinal nematode eggs in dog feces collected in public parks of Mérida,Yucatán, México. MATERIALS AND METHODS: A total of 100 dog fecal samples collected from 20 public parks in two areas of Mérida were analyzed...
March 15, 2018: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29668134/-anti-trypanosoma-cruzi-antibodies-in-latin-american-migrants-in-transit-through-the-m%C3%A3-xico-usa-border
#2
Laura Mayela Montes-Rincón, Lucio Galaviz-Silva, Zinnia Judith Molina-Garza
INTRODUCTION: In recent years, American trypanosomiasis has become an emergent public health problem in countries receiving migrant populations such as México, USA, Canada or those in Europe. OBJECTIVE: To analyze the prevalence of anti-Trypanosoma cruzi antibodies in Latin American migrants on their way to USA and Canada by means of serological techniques. MATERIAL AND METHODS: ELISA and IHA were performed to detect anti-T. cruzi antibodies...
March 15, 2018: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29668121/lipofection-of-plasmid-dna-into-human-mast-cell-lines-using-lipid-nanoparticles-generated-by-microfluidic-mixing
#3
Brett A Duguay, Kate Wei-Chen Huang, Marianna Kulka
Mast cells are important immune cells that have significant roles in mediating allergy and asthma. Therefore, studying the molecular mechanisms regulating these and other processes in mast cells is important to elucidate. Methods such as lipofection, transduction, and electroporation are often employed to dissect these mechanisms by disrupting gene expression in mast cell lines. However, as with other leukocytes, human mast cells (HMCs) are often refractory to the delivery of plasmids by lipofection. In this study, we investigated the utility of lipid nanoparticles (LNPs) containing the ionizable cationic lipids 1,2-dioleoyloxy-3-dimethylaminopropane, 1,2-dioleyloxy-3-dimethylaminopropane, or 2,2-dilinoleyl-4-(2-dimethylaminoethyl)-[1,3]-dioxolane for the delivery of plasmid DNA into HMC lines...
April 18, 2018: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/29668108/sonographic-assessment-of-swallowing-in-irradiated-nasopharyngeal-carcinoma-patients
#4
Dennis T H Cheng, Kathy Y S Lee, Anil T Ahuja, Michael C F Tong
OBJECTIVES/HYPOTHESIS: Ultrasonography is an emerging clinical tool to study the dysfunction of swallowing muscles. This was the first sonographic study to assess the relationship between suprahyoid muscle contraction, hyoid bone displacement, and penetration-aspiration status (PAS) during swallowing in nasopharyngeal carcinoma (NPC) patients treated with radiotherapy (RT). The study also aimed to establish reliability data for the sonographic technique described. STUDY DESIGN: Cross-sectional study...
April 18, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29668079/co-culture-of-adipose-derived-stem-cells-and-chondrocytes-on-three-dimensionally-printed-bioscaffolds-for-craniofacial-cartilage-engineering
#5
Robert J Morrison, Hassan B Nasser, Khaled N Kashlan, David A Zopf, Derek J Milner, Colleen L Flanangan, Matthew B Wheeler, Glenn E Green, Scott J Hollister
OBJECTIVES/HYPOTHESIS: Reconstruction of craniofacial cartilagenous defects are among the most challenging surgical procedures in facial plastic surgery. Bioengineered craniofacial cartilage holds immense potential to surpass current reconstructive options, but limitations to clinical translation exist. We endeavored to determine the viability of utilizing adipose-derived stem cell-chondrocyte co-culture and three-dimensional (3D) printing to produce 3D bioscaffolds for cartilage tissue engineering...
April 18, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29668030/uv-c-irradiation-on-the-quality-of-green-tea-effect-on-catechins-antioxidant-activity-and-cytotoxicity
#6
Matthew J Vergne, Ankit Patras, Manreet S Bhullar, Lincoln M Shade, Michael Sasges, Kanyasiri Rakariyatham, Che Pan, Hang Xiao
Short-wavelength ultraviolet (UV-C) irradiation is a nonthermal processing technique that is a possible alternative to the heat-pasteurization of tea beverages. This study investigated the effect of UV-C irradiation on the polyphenolic and total phenolic contents of a green tea beverage and analyzed cytotoxicity of irradiated green tea using a novel continuous flow-through UV system. UV-C fluence levels ranging from 0 to 240 mJ/cm2 were delivered to green tea, and polyphenols were chemically profiled. Continuous-flow UV-C irradiation of the green tea beverage at a fluence of 68 mJ/cm2  induced a minor reduction in the concentration of the most abundant catechin in green tea, (-)-epigallocatechin gallate (EGCG), from 145 to 131...
April 18, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29667882/new-doppler-imaging-technique-for-assessing-angiogenesis-in-breast-tumors-correlation-with-immunohistochemically-analyzed-microvessels-density
#7
Sewha Kim, Hye Jin Lee, Kyung Hee Ko, Ah Young Park, Jieun Koh, Hae Kyoung Jung
Background Microvessel density (MVD) is associated with grade and prognosis in breast tumors. However, conventional color Doppler flow (CDF) imaging has been limited to represent MVD of breast tumors. Purpose To evaluate whether a new Doppler imaging technique (AngioPLUS) can represent MVD of breast tumors. Material and Methods The institutional review board approved this retrospective study, and patients' informed consent was waived. CDF and AngioPLUS were available in pathologically confirmed 55 breast tumors of 53 women...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29667874/evaluation-of-a-test-and-cull-strategy-for-reducing-prevalence-of-chronic-wasting-disease-in-mule-deer-odocoileus-hemionus
#8
Lisa L Wolfe, Mary Kay Watry, Michael A Sirochman, Tracey M Sirochman, Michael W Miller
  We evaluated a test and cull strategy for lowering chronic wasting disease (CWD) prevalence in a naturally-infected, free-ranging mule deer ( Odocoileus hemionus) herd wintering in the town of Estes Park, Colorado, USA and in nearby Rocky Mountain National Park. We tested 48-68% of the estimated number of adult (≥1 yr old) deer annually for 5 yr via tonsil biopsy immunohistochemistry (IHC), collecting 1,251 samples from >700 individuals and removing IHC-positive deer. Among males, CWD prevalence during the last 3 yr of selective culling was lower (one-sided Fisher's exact test P=0...
April 18, 2018: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/29667870/focus-is-key-panic-focused-interpretations-are-associated-with-symptomatic-improvement-in-panic-focused-psychodynamic-psychotherapy
#9
John R Keefe, Nili Solomonov, Robert J Derubeis, Alexander C Phillips, Fredric N Busch, Jacques P Barber, Dianne L Chambless, Barbara L Milrod
OBJECTIVE: This study examines whether, in panic-focused psychodynamic psychotherapy (PFPP), interpretations of conflicts that underlie anxiety (panic-focused or PF-interpretations) are specifically associated with subsequent panic disorder (PD) symptom improvement, over and above the provision of non-symptom-focused interpretations. METHOD: Technique use in Sessions 2 and 10 of a 24-session PFPP protocol was assessed for the 65 patients with complete outcome data randomized to PFPP in a two-site trial of psychotherapies for PD...
April 18, 2018: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://www.readbyqxmd.com/read/29667853/evaluation-and-management-of-subchondral-calcium-phosphate-injection-technique-to-treat-bone-marrow-lesion
#10
Diego Costa Astur, Eduardo Vasconcelos de Freitas, Pedro Barreira Cabral, Caio Carvalho Morais, Bruno Silveira Pavei, Camila Cohen Kaleka, Pedro Debieux, Moises Cohen
Purpose This study aimed to compile available data in medical literature about subchondral calcium phosphate injection, comparing results obtained with this technique, as well as indications, complications, and other important factors in treatment of bone marrow lesions. Designs A literature review using PubMed and Medline database in order to identify works with terms "subchondral calcium phosphate injection," " subchondroplasty®," "bone marrow lesion," and "knee." Eight relevant articles were found...
April 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29667836/molecular-dynamics-simulations-are-redefining-our-view-of-peptides-interacting-with-biological-membranes
#11
Jakob P Ulmschneider, Martin B Ulmschneider
Ever since the first molecular mechanics computer simulations of biological molecules became possible, there has been the dream to study all complex biological phenomena in silico, simply bypassing the enormous experimental challenges and their associated costs. For this, two inherent requirements need to be met: First, the time scales achievable in simulations must reach up to the millisecond range and even longer. Second, the computational model must accurately reproduce what is measured experimentally. Despite some recent successes, the general consensus in the field to date has been that neither of these conditions have yet been met and that the dream will be realized, if at all, only in the distant future...
April 18, 2018: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29667668/synthesis-of-fused-pyrroles-containing-4-hydroxycoumarins-by-regioselective-metal-free-multicomponent-reactions
#12
Richa Mishra, Asim Jana, Anoop Kumar Panday, Lokman H Choudhury
The reaction of arylglyoxals, 4-hydroxycoumarin, and aromatic amines such as 7-amino-2-methylchromone, 6/7-aminoflavone, 7-amino-4-methylcoumarin, 1-amino-9-fluorenone, 1-aminoanthraquinone and aniline derivatives in acetic acid medium under microwave conditions provides the corresponding regioselective fused pyrroles having hydroxycoumarin and aryl substituents. Alternatively, we have developed another method using in situ arylglyoxals from acetophenone derivatives by I2/DMSO promoted C-H oxidation followed by one-pot three component cyclization reactions to provide similar fused pyrroles...
April 18, 2018: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29667598/a-random-phased-array-for-mr-guided-transcranial-ultrasound-neuromodulation-in-non-human-primates
#13
Vandiver Chaplin, Marshal A Phipps, Charles F Caskey
Transcranial focused ultrasound (FUS) is a non-invasive technique for therapy and study of brain neural activation. Here we report on the design and characterization of a new MR-guided FUS transducer for neuromodulation in non-human primates at 650 kHz. The array is randomized with 128 elements 6.6 mm in diameter, radius of curvature 7.2 cm, opening diameter 10.3 cm (focal ratio 0.7), and 46% coverage. Simulations were used to optimize transducer geometry with respect to focus size, grating lobes, and directivity...
April 18, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29667559/improving-the-rhinomanometry-technique-using-benzoin-tincture
#14
F Arslan, Ü Yıldızoğlu, A Durmaz, S Çetinkaya
OBJECTIVE: In order to achieve a faster and more reliable anterior rhinomanometric evaluation, nasal skin was prepared using benzoin tincture solution, which provides simpler and better adhesion of the foam tape to the nasal skin. METHOD: Two consecutive anterior rhinomanometry measurements were made, one with and one without benzoin tincture application. RESULTS: The average time taken to perform classic foam tape anterior rhinomanometry without benzoin tincture application was 281...
April 18, 2018: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/29667558/ga-68-nanoparticles-and-ultra-small-nanoparticle-next-generation-of-pet-radiopharmaceuticals
#15
Mohammed Al-Qahtani, Yousif Al Malki, Hadeel Mutwali, Edward Helal-Neto, Ralph Santos-Oliveira
BACKGROUND AND OBJECTIVE: The future of medicine relies on the capability to forecast the future and in the development of new drugs. The same rationale is applied to radiopharmacy. In this direction the development of nano-radiopharmaceuticals represents the most effective glance of the future. METHODS: In this manuscript we developed an efficient, rapid and direct methodology to label ultra-small polymeric nanoparticle (10 to 12 nm) and regular polymeric nanoparticles (200 to 210 nm), both obtained by double emulsion technique, with Ga-68 in order to promote the development of PET-nanoradiopharmaceuticals...
April 17, 2018: Current Radiopharmaceuticals
https://www.readbyqxmd.com/read/29667550/in-vitro-studies-on-cytotoxic-dna-protecting-antibiofilm-and-antibacterial-effects-of-biogenic-silver-nanoparticles-prepared-with-bergenia-ciliata-rhizome-extract
#16
Ghazna Zia, Haleema Sadia, Shabnam Nazir, Kiren Ejaz, Shaukat Ali, Ihsan-Ul-Haq, Tariq Iqbal, Muhammad Abdul Rauf Khan, Abida Raza, Saiqa Andleeb
BACKGROUND: Many health hazardous diseases are caused by clinical pathogens. Drug-resistant microbes are one of the major health problems in the world. To overcome the effect of infectious diseases new antimicrobial agent from nature has been explored which is environmentally friendly, less costly and more effective for the development of next-generation drugs. Bergenia ciliata and silver nitrate both have medicinal properties. OBJECTIVES: The aim of the current research was to evaluate the cytotoxic, and antibacterial effect of green synthesized nanoparticles using Bergenia ciliata rhizome against clinical bacterial pathogens...
April 17, 2018: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/29667524/optimization-of-the-extraction-of-bioactive-molecules-from-lycium-barbarum-fruits-and-evaluation-of-the-antioxidant-activity-a-combined-study
#17
Chiara Povolo, Alberto Foschini, Giovanni Ribaudo
Novel food, super food, wolfberry, the Himalayan longevity fruit. Several different and, even more, colourful names define the fruits of Lycium barbarum L., one of the most popular food supplements and anti-aging remedies of the recent years. Goji derivatives find application at the interface between food and medicine thanks to the claimed antioxidant and immunomodulatory properties. Aiming at identifying the most effective extraction protocol for processing different goji berries samples (fresh and dried, commercial and from an Italian cultivar), combinations of extractive and analytical techniques were attempted...
April 18, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29667519/an-investigation-of-factors-affecting-the-performance-of-wheelchair-transfers
#18
Giulia Barbareschi, Catherine Holloway
PURPOSE: Being able to transfer in and out of their wheelchair is an important task for wheelchair users that can be affected by a variety of different factors. The aim of this study was to investigate the interplay between personal characteristics, wheelchair users' transferring technique and the other factors that can affect the performance of wheelchair transfers. METHOD: A cross-sectional survey study was designed to recruit wheelchair users, aged 18 or older, performing sitting-pivot or standing-pivot wheelchair transfers, independently or with assistance...
April 18, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29667512/alternative-technique-to-transfer-jaw-relations-for-custom-mandibular-advancement-devices-a-case-report
#19
Filiz Keyf, Defne Burduroğlu, Selma Fırat Güven, Bülent Çiftçi
Background Oral appliance therapy for obstructive sleep apnea can be helpful in mild and moderate cases. This clinical report evaluates the efficacy of a protocol that predicts an optimal jaw position and describes the response of a young OSA patient to treatment. Clinical Presentation A 27-year-old woman was diagnosed with moderate OSA and had an apnea-hypopnea index (AHI) of 25.8/hr. In order to fabricate a custom device, an alternative procedure to determine the optimal protrusion and vertical positioning of the jaw was applied...
April 18, 2018: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/29667490/book-review-endoscopic-sinus-surgery-anatomy-three-dimensional-reconstruction-and-surgical-technique-wormald-peter-john-endoscopic-sinus-surgery-anatomy-three-dimensional-reconstruction-and-surgical-technique-4th-ed-adelaide-australia-thieme-2018-hard-cover
#20
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