keyword
MENU ▼
Read by QxMD icon Read
search

Acute cervical spinal cord injury

keyword
https://www.readbyqxmd.com/read/28107239/management-of-pharyngeal-fistulas-after-anterior-cervical-spine-surgery-a-treatment-algorithm-for-severe-complications
#1
Christian Simon, Carl H Fürstenberg, Markus Eichler, Stefan Rohde, Cem Bulut, Bernd Wiedenhöfer
STUDY DESIGN: This study is a retrospective database query to identify all anterior spinal approaches. OBJECTIVES: The objectives were to assess all patients with pharyngocutaneous fistulas (PCFs) after anterior cervical spine surgery. SUMMARY OF BACKGROUND DATA: Patients with the diagnosis of PCFs were treated at the University of Heidelberg Spine Medical Center, Spinal Cord Injury Unit and Department of Otolaryngology (Germany), between 2005 and 2011...
February 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28056284/-clinical-value-of-diffusion-tensor-imaging-parameter-value-in-evaluating-the-prognosis-of-spinal-cord-injury-in-acute-cervical-spinal-cord-injury
#2
Z M Zou, J Li, Q Y Cao, H X Lian, C N He, B Wang
Objective: To evaluate the clinical application value of diffusion tensor imaging (DTI) parameter in evaluating the prognosis of spinal cord injury in acute cervical spinal cord injury. Method: From October 2012 to December 2015, a total of 23 patients with acute cervical spinal cord injury were examined by routine MRI-T2WI high signal DTI examination, according to the American Spinal Injury Association (ASIA) damage standard. One month later according to the functional outcome of the spinal cord, all patients were divided into non improvement group (group A) 4 cases (2 cases of ASIA-A, 2 cases of grade B) and improvement group (group B) 19 cases (13 cases of ASIA-C, 5 cases of grade D, 1 case of grade B), 15 cases of healthy volunteers as the normal group (group C )...
January 3, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28053621/clinical-and-magnetic-resonance-imaging-features-of-compressive-cervical-myelopathy-with-traumatic-intervertebral-disc-herniation-in-cynomolgus-macaque-macaca-fascicularis
#3
Yun-Jung Choi, Hye-Jin Park, Chul-Ho Sohn, Kyeong Cheon Jung, Seong Hoe Park, Jae-Il Lee
Intervertebral disc herniation (IVDH) with nucleus pulposus extrusion, traumatic or not, is a devastating clinical condition accompanied by neurological problems. Here we report a cynomolgus macaque suffering from acute and progressive neurological dysfunction by a blunt trauma due to neck collar, an animal handling device. Tetraplegia, urinary incontinence, decreased proprioception, and imperception of pain were shown on physical and neurological examinations. MRI sagittal T2 weighted sequences revealed an extensive protrusion of disc material between C2 and C3 cervical vertebra, and this protrusion resulted in central stenosis of the spinal cord...
December 2016: Laboratory Animal Research
https://www.readbyqxmd.com/read/28018284/developmental-changes-in-pain-and-spinal-immune-gene-expression-after-radicular-trauma-in-the-rat
#4
Gordon A Barr, Shaoning Wang, Christine L Weisshaar, Beth A Winkelstein
Neuropathic pain is chronic pain that develops after nerve injury and is less frequent in infants and children than in adults. Likewise, in animal models of neuropathic pain, allodynia and hyperalgesia are non-existent or attenuated in the infant, with a "switch" during development by which acute nerve injury transitions to chronic pain. Concomitant with the delay in neuropathic pain, there is a parallel delay in the ability of nerve injury to activate the immune system. Models of neuropathic pain in the infant have used various ligation methods and find that neuropathic pain does not occur under after postnatal days 21-28 (PN21-PN28), linked to activation of immune processes and developmental regulation of anti-inflammatory cytokines...
2016: Frontiers in Neurology
https://www.readbyqxmd.com/read/28007771/multivariate-analysis-of-mri-biomarkers-for-predicting-neurologic-impairment-in-cervical-spinal-cord-injury
#5
J Haefeli, M C Mabray, W D Whetstone, S S Dhall, J Z Pan, P Upadhyayula, G T Manley, J C Bresnahan, M S Beattie, A R Ferguson, J F Talbott
BACKGROUND AND PURPOSE: Acute markers of spinal cord injury are essential for both diagnostic and prognostic purposes. The goal of this study was to assess the relationship between early MR imaging biomarkers after acute cervical spinal cord injury and to evaluate their predictive validity of neurologic impairment. MATERIALS AND METHODS: We performed a retrospective cohort study of 95 patients with acute spinal cord injury and preoperative MR imaging within 24 hours of injury...
December 22, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27995938/a-radiographic-evaluation-of-facet-sagittal-angle-in-cervical-spinal-cord-injury-without-major-fracture-or-dislocation
#6
T Takao, K Kubota, T Maeda, S Okada, Y Morishita, E Mori, I Yugue, O Kawano, H Sakai, T Ueta, K Shiba
STUDY DESIGN: A retrospective radiographic study with a minimum 2-year follow-up. OBJECTIVE: To evaluate the relationships between the cervical articular facets' morphology and the incidence of traumatic cervical spinal cord injury (CSCI) without major fracture or dislocation. SETTING: Spinal Injuries Center, Japan. METHODS: This study included 113 patients with traumatic CSCI without major fracture or dislocation. Eighty-four healthy volunteers without neurological deficits or cervical cord pathology on magnetic resonance imaging (MRI) were defined as control subjects...
December 20, 2016: Spinal Cord
https://www.readbyqxmd.com/read/27933357/bilateral-increases-in-erk-activation-at-the-spinomedullary-junction-region-by-acute-masseter-muscle-injury-during-temporomandibular-joint-inflammation-in-the-rats
#7
Masayuki Kurose, Hiroki Imbe, Yosuke Nakatani, Mana Hasegawa, Noritaka Fujii, Ritsuo Takagi, Kensuke Yamamura, Emiko Senba, Keiichiro Okamoto
We determined the role of persistent monoarthritis of temporomandibular joint region (TMJ) on bilateral masseter muscle (MM) nociception in male rats using orofacial nocifensive behaviors, phosphorylated extracellular signal-regulated kinase and Fos induction at the trigeminal subnucleus caudalis/upper cervical spinal cord (Vc/C2) region in response to formalin injection to the MM region. TMJ inflammation was induced by local injection of CFA into the left TMJ region. Orofacial nocifensive behaviors evoked by formalin injection ipsilateral or contralateral to the TMJ inflammation appeared to be increased at 1-14 days or at 1, 10 and 14 days after induction of TMJ inflammation, respectively, while increases in behavioral duration were seen mainly in the late phase rather than the early phase...
December 8, 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/27927784/adenosine-dependent-phrenic-motor-facilitation-is-inflammation-resistant
#8
Ibis M Agosto-Marlin, Nicole L Nichols, Gordon S Mitchell
Phrenic motor facilitation (pMF) can be elicited by acute intermittent hypoxia (ie. phrenic long-term facilitation, or pLTF), or direct application of pharmacological agonists to the cervical spinal cord. Moderate acute intermittent hypoxia (mAIH, 3X5 min episodes of 35-50 mmHg arterial PO2, 5 min normoxic intervals) induces pLTF by a serotonin-dependent mechanism; mAIH-induced pLTF is abolished by even low levels of systemic inflammation induced by lipopolysaccharide (LPS, 100ug/kg i.p.). In contrast, severe AIH (sAIH, 3X5 min episodes of 25-30mmHg arterial PO2, 5 min intervals) elicits pLTF by a distinct, adenosine-dependent mechanism...
December 7, 2016: Journal of Neurophysiology
https://www.readbyqxmd.com/read/27898477/costs-and-length-of-stay-for-the-acute-care-of-patients-with-motor-complete-spinal-cord-injury-following-cervical-trauma-the-impact-of-early-transfer-to-specialized-acute-sci-center
#9
Andréane Richard-Denis, Debbie Ehrmann Feldman, Cynthia Thompson, Étienne Bourassa-Moreau, Jean-Marc Mac-Thiong
OBJECTIVE: Acute spinal cord injury (SCI) centers aim to optimize outcome following SCI. However, there is no timeframe to transfer patients from regional to SCI centers in order to promote cost-efficiency of acute care. Our objective was to compare costs and length of stay (LOS) following early and late transfer to the SCI center. DESIGN: A retrospective cohort study involving 116 individuals was conducted. Group 1 (n = 87) was managed in an SCI center promptly after the trauma, whereas group 2 (n = 29) was transferred to the SCI center only after surgery...
November 24, 2016: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/27881723/intraspinal-microstimulation-and-diaphragm-activation-following-cervical-spinal-cord-injury
#10
Lynne M Mercier, Elisa J Gonzalez-Rothi, Kristi A Streeter, Savannah S Posgai, Alexander S Poirier, David D Fuller, Paul J Reier, David M Baekey
Intraspinal microstimulation (ISMS), using implanted electrodes, can evoke locomotor movements after spinal cord injury (SCI), but has not been explored in the context of respiratory motor output. An advantage over epidural and direct muscle stimulation is the potential of ISMS to selectively stimulate components of the spinal respiratory network. The present study tested the hypothesis that medullary respiratory activity could be used to trigger mid-cervical ISMS and diaphragm motor unit activation in rats with cervical SCI...
November 23, 2016: Journal of Neurophysiology
https://www.readbyqxmd.com/read/27881040/a-single-dose-of-docosahexaenoic-acid-increases-the-functional-recovery-promoted-by-rehabilitation-after-cervical-spinal-cord-injury-in-the-rat
#11
Zhou-Hao Liu, Ping K Yip, John V Priestley, Adina T Michael-Titus
Task-specific rehabilitation has been shown to promote functional recovery after acute spinal cord injury (SCI). Recently, the omega-3 polyunsaturated fatty acid, docosahexaenoic acid (DHA), has been shown to promote neuroplasticity after SCI. Here, we investigated whether the combination of a single bolus of DHA with rehabilitation can enhance the effect of DHA or rehabilitation therapy in adult injured spinal cord. We found enhanced functional improvement with DHA in combination with rehabilitation compared with either treatment alone in a rat cervical lateral hemisection SCI model...
January 13, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27843686/effect-of-spinal-cord-compression-on-local-vascular-blood-flow-and-perfusion-capacity-by-alshareef-m-krishna-v-ferdous-j-aishareef-a-kindy-m-kolachalama-vb-et-al
#12
Nancy E Epstein
BACKGROUND: Different degrees of blood flow/vascular compromise occur with anterior, posterior, or circumferential spinal cord compression/spinal cord injury (SCI). SCI is also divided into primary and secondary injury. Primary SCI refers to the original neurological damage to tissues, whereas secondary injury reflects interruption of normal blood flow leading to further inflammatory response/other local changes which contribute to additional neurological injury. METHODS: The authors developed a quantitative "3-D finite element fluid structure interaction model" of spinal cord blood flow to better document the mechanisms of secondary ischemic damage occurring in the spinal cord anteriorly, posteriorly, or circumferentially...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27842476/recurrent-neurologic-deterioration-after-conservative-treatment-for-acute-traumatic-central-cord-syndrome-without-bony-injury-17-operative-cases-report%C3%AF
#13
Wenjie Jin, Xin Sun, Jia Wang, Xingzhen Liu, Xiushuai Shang, Hairong Tao, Tong Zhu, Kangping Shen
The mechanisms of late recurrent neurologic deterioration after conservative treatment for acute traumatic central cord syndrome (ATCCS) remained unclear. 17 operative cases sustaining late recurrent neurologic deterioration after conservative treatment for ATCCS were reviewed to investigate the mechanisms. The assessment of neurological status was based on International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI). Gender, age, cause of injury, results of image, conservative treatment and operative data, neurological status on different time points were recorded...
November 14, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27834292/mesenteric-vascular-dysregulation-and-intestinal-inflammation-accompanies-experimental-spinal-cord-injury
#14
Emily M Besecker, Gina M Deiter, Nicole Pironi, Timothy K Cooper, Gregory M Holmes
Cervical and high thoracic spinal cord injury (SCI) drastically impairs autonomic nervous system function. Individuals with SCI at thoracic spinal level 5 (T5) or higher often present cardiovascular disorders that include resting systemic arterial hypotension. Gastrointestinal (GI) tissues are critically dependent upon adequate blood flow and even brief periods of visceral hypoxia triggers GI dysmotility. The aim of this study was to test the hypothesis that T3-SCI induces visceral hypoperfusion, diminished postprandial vascular reflexes, and concomitant visceral inflammation...
January 1, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/27762167/demographic-and-clinical-characteristics-of-persons-with-spinal-cord-injury-in-turkey-one-year-experience-of-a-primary-referral-rehabilitation-center
#15
Özlem Taşoğlu, Engin Koyuncu, Rabia Daylak, Derya Yumuşak Karacif, Zerrin I Nce, Didem Yenigün, Neşe Özgirgin
OBJECTIVE: To define the demographic and clinical characteristics of persons with spinal cord injury, rehabilitated in a primary referral rehabilitation center in Turkey. DESIGN: Retrospective study. SETTING: Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey Methods: Medical records of all patients with spinal cord injury (acute-subacute-chronic) at a single academic referral center over the course of one year were reviewed...
October 20, 2016: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/27670805/identification-of-patients-with-cervical-sci-suitable-for-early-nerve-transfer-to-achieve-hand-opening
#16
J W Simcock, J A Dunn, N T Buckley, K D Mohammed, G P Beadel, A G Rothwell
STUDY DESIGN: Retrospective audit. OBJECTIVES: The objective of this study was to identify the proportion of patients with cervical spinal cord injury who would potentially benefit from nerve transfer surgery to gain active hand opening, and to determine when a safe nerve transfer decision can be made. SETTING: Christchurch, New Zealand. METHODS: Case note review of the first 12 months following acute cervical spinal cord injury (2007-2012)...
September 27, 2016: Spinal Cord
https://www.readbyqxmd.com/read/27642819/traumatic-sports-related-cervical-spine-injuries
#17
Varun Puvanesarajah, Rabia Qureshi, Jourdan M Cancienne, Hamid Hassanzadeh
Cervical spine trauma in the athlete is not an insignificant occurrence with possibly catastrophic results. Football remains one of the most common and most well studied sporting activities associated with spine injuries. Transient spinal cord and peripheral nerve injuries may manifest as quadriparesis or burners/stingers with symptoms that resolve completely. More severe spinal cord injuries, typically from axial loading on the cervical spine, will cause bilateral symptoms with residual neurological deficit...
September 16, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27630612/monitoring-upper-limb-recovery-after-cervical-spinal-cord-injury-insights-beyond-assessment-scores
#18
Michael Brogioli, Sophie Schneider, Werner L Popp, Urs Albisser, Anne K Brust, Inge-Marie Velstra, Roger Gassert, Armin Curt, Michelle L Starkey
BACKGROUND: Preclinical investigations in animal models demonstrate that enhanced upper limb (UL) activity during rehabilitation promotes motor recovery following spinal cord injury (SCI). Despite this, following SCI in humans, no commonly applied training protocols exist, and therefore, activity-based rehabilitative therapies (ABRT) vary in frequency, duration, and intensity. Quantification of UL recovery is limited to subjective questionnaires or scattered measures of muscle function and movement tasks...
2016: Frontiers in Neurology
https://www.readbyqxmd.com/read/27626139/vagal-control-of-breathing-pattern-after-midcervical-contusion-in-rats
#19
Kun-Ze Lee, Hsiang-Chun Kuo
The present study was designed to establish a midcervical contusion model that can simulate long-term respiratory deficits, and investigate the breathing pattern during vagal-mediated respiratory reflexes following midcervical contusion. Moderate and severe (impactor height: 6.25 or 12.5 mm) contusion was induced at midline C3-4 spinal cord in adult Sprague-Dawley rats. The ventilatory behaviors of unanesthetized were evaluated by whole body plethysmography at 1 day and 1, 2, 4, and 8 weeks post-injury. The tidal volume was decreased and frequency was increased in contused animals compared with uninjured animals at the acute injury state...
October 13, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27621643/does-surgical-treatment-within-4-hours-after-trauma-have-an-influence-on-neurological-remission-in-patients-with-acute-spinal-cord-injury
#20
Bahram Biglari, Christopher Child, Timur Mert Yildirim, Tyler Swing, Tim Reitzel, Arash Moghaddam
BACKGROUND: The proper timing for surgery in patients with acute spinal cord injury is controversial. This study was conducted to detect if there is an advantage in early (within the first 4 hours after trauma) compared to late (between 4 and 24 hours after trauma) surgery on neurological outcome. METHODS: In this single institution prospective cohort study, data were analyzed from 51 spinal cord injured patients with an average age of 43.4 (±19.2) years. The influence of early (29 patients within the first 4 hours) as opposed to late (22 patients between 4 and 24 hours) decompression was evaluated by comparing data for neurological outcome...
2016: Therapeutics and Clinical Risk Management
keyword
keyword
114799
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"