keyword
MENU ▼
Read by QxMD icon Read
search

Propel

keyword
https://www.readbyqxmd.com/read/28098324/ionic-screening-and-dissociation-are-crucial-for-understanding-chemical-self-propulsion-in-polar-solvents
#1
Aidan T Brown, Wilson C K Poon, Christian Holm, Joost de Graaf
Polar solvents like water support the bulk dissociation of themselves and their solutes into ions, and the re-association of these ions into neutral molecules in a dynamic equilibrium, e.g., H2O2 ⇌ H(+) + HO2(-). Using continuum theory, we study the influence of these association-dissociation reactions on the self-propulsion of colloids driven by surface chemical reactions (chemical swimmers). We find that association-dissociation reactions should have a strong influence on swimmers' behaviour, and therefore should be included in future modelling...
January 18, 2017: Soft Matter
https://www.readbyqxmd.com/read/28098286/tridentate-lewis-acids-based-on-triphenylsilane
#2
Janek Tomaschautzky, Beate Neumann, Hans-Georg Stammler, Andreas Mix, Norbert W Mitzel
Several derivatives of the propeller-shaped ortho-substituted triphenylsilanes, carrying metal- or silicon-based acceptor groups, are reported. They were synthesized starting from tris(2-bromophenyl)fluorosilane, tris(2-vinylphenyl)fluorosilane and tris(2-ethynylphenyl)fluorosilane to generate a scope of Lewis-acidic molecules with different cavities. An improved synthetic protocol for donor-free tris(2-lithiophenyl)silanes is described. First attempts in host-guest chemistry to probe the binding between a threefold alane-functionalised ortho-substituted triphenylsilane and a tridentate Lewis-basic guest molecule are presented...
January 18, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28098273/high-definition-infrared-chemical-imaging-of-colorectal-tissue-using-a-spero-qcl-microscope
#3
B Bird, J Rowlette
Mid-infrared microscopy has become a key technique in the field of biomedical science and spectroscopy. This label-free, non-destructive technique permits the visualisation of a wide range of intrinsic biochemical markers in tissues, cells and biofluids by detection of the vibrational modes of the constituent molecules. Together, infrared microscopy and chemometrics is a widely accepted method that can distinguish healthy and diseased states with high accuracy. However, despite the exponential growth of the field and its research world-wide, several barriers currently exist for its full translation into the clinical sphere, namely sample throughput and data management...
January 18, 2017: Analyst
https://www.readbyqxmd.com/read/28097509/revealing-pmdi-spray-initial-conditions-flashing-atomisation-and-the-effect-of-ethanol
#4
Nicholas Mason-Smith, Daniel J Duke, Alan L Kastengren, Daniela Traini, Paul M Young, Yang Chen, David A Lewis, Daniel Edgington-Mitchell, Damon Honnery
PURPOSE: Sprays from pressurised metered-dose inhalers are produced by a transient discharge of a multiphase mixture. Small length and short time scales have made the investigation of the governing processes difficult. Consequently, a deep understanding of the physical processes that govern atomisation and drug particle formation has been elusive. METHODS: X-ray phase contrast imaging and quantitative radiography were used to reveal the internal flow structure and measure the time-variant nozzle exit mass density of 50 µL metered sprays of HFA134a, with and without ethanol cosolvent...
January 17, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28092836/antiviral-drug-acyclovir-exhibits-antitumor-activity-via-targeting-%C3%AE-trcp1-molecular-docking-and-dynamics-simulation-study
#5
Shagufta Shafique, Sajid Rashid
The critical role of βTrCP1 in cancer development makes it a discerning target for the development of small drug like molecules. Currently, no inhibitor exists that is able to target its substrate binding site. Through molecular docking and dynamics simulation assays, we explored the comparative binding pattern of βTrCP1-WD40 domain with ACV and its phospho-derivatives (ACVMP, ACVDP and ACVTP). Consequently, through principal component analysis, βTrCP1-ACVTP was found to be more stable complex by obscuring a reduced conformational space than other systems...
December 31, 2016: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/28088866/a-combined-experimental-and-computational-study-on-the-unimolecular-decomposition-of-jp-8-jet-fuel-surrogates-ii-n-dodecane-n-c12h26
#6
Long Zhao, Tao Yang, Ralf I Kaiser, Tyler Patrick Troy, Musahid Ahmed, Joao Marcelo Ribeiro, Daniel Belisario-Lara, Alexander Moiseevich Mebel
We investigated temperature-dependent products in the pyrolysis of helium-seeded n-dodecane, which represents a surrogate of the n-alkane fraction of Jet Propellant-8 (JP-8) aviation fuel. The experiments were performed in a high temperature chemical reactor over a temperature range of 1,200 K to 1,600 K at a pressure of 600 Torr, with in situ identification of the nascent products in a supersonic molecular beam using single photon vacuum ultraviolet (VUV) photoionization coupled with the analysis of the ions in a reflectron time-of-flight mass spectrometer (ReTOF)...
January 16, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28088860/a-combined-experimental-and-computational-study-on-the-unimolecular-decomposition-of-jp-8-jet-fuel-surrogates-i-n-decane-n-c10h22
#7
Long Zhao, Tao Yang, Ralf I Kaiser, Tyler Patrick Troy, Musahid Ahmed, Daniel Belisario-Lara, Joao Marcelo Ribeiro, Alexander Moiseevich Mebel
Exploiting a high temperature chemical reactor, we explored the pyrolysis of helium-seeded n-decane as a surrogate of the n-alkane fraction of Jet Propellant-8 (JP-8) over a temperature range of 1,100 K to 1,600 K at a pressure of 600 Torr. The nascent products were identified in situ in a supersonic molecular beam via single photon vacuum ultraviolet (VUV) photoionization coupled with a mass spectroscopic analysis of the ions in a reflectron time-of-flight mass spectrometer (ReTOF). Our studies probe, for the first time, the initial reaction products formed in the decomposition of n-decane - including radicals and thermally labile closed-shell species effectively excluding mass growth processes...
January 16, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28088718/highly-efficient-inactivation-of-bacteria-found-in-drinking-water-using-chitosan-bentonite-composites-modelling-and-breakthrough-curve-analysis
#8
Sarah C Motshekga, Suprakas Sinha Ray
Disinfection of bacterially-contaminated drinking water requires a robust and effective technique and can be achieved by using an appropriate disinfectant material. The advanced use of nanomaterials is observed as an alternative and effective way for the disinfection process and water treatment as a whole. Hence, the inactivation of Escherichia coli (E. coli) using chitosan-Bentonite (Cts-Bent) composites was studied in a fixed bed column. Cts-Bent composites were synthesized using in situ cross-linking method using Bent-supported silver and zinc oxide nanoparticles...
January 3, 2017: Water Research
https://www.readbyqxmd.com/read/28079956/an-exonuclease-iii-powered-on-particle-stochastic-dna-walker
#9
Xiangmeng Qu, Dan Zhu, Guangbao Yao, Shao Su, Jie Chao, Huajie Liu, Xiaolei Zuo, Lihua Wang, Jiye Shi, Lianhui Wang, Wei Huang, Hao Pei, Chunhai Fan
DNA-based machines have attracted rapidly growing interest owing to their potential in drug delivery, biocomputing, and diagnostic applications. Herein, we report a type of exonuclease III (Exo III)-powered stochastic DNA walker that can autonomously move on a spherical nucleic acid (SNA)-based 3D track. The motion is propelled by unidirectional Exo III digestion of hybridized DNA tracks in a burnt-bridge mechanism. The operation of this Exo III-propelled DNA walker was monitored in real time and at the single-particle resolution using total internal reflection fluorescence microscopy (TIRF)...
January 12, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28079008/walking-a-tightrope-a-perspective-of-resveratrol-effects-on-breast-cancer
#10
Caterina Bartolacci, Cristina Andreani, Augusto Amici, Cristina Marchini
It is an acknowledged fact that health benefits are derived from fruit- and vegetables-enriched diets. In particular, polyphenols, compounds bearing one or more hydroxyl groups attached to an aromatic ring, are ascribed for most of such beneficial effects. Among them, resveratrol, a phytoalexin found in numerous plant species, and more notably in grapes, has widely piqued the interest of the scientific community by virtue of its anti-aging, anti-inflammatory and anti-oxidant properties. Moreover, evidence claiming resveratrol ability to hinder processes underlying all the three steps of carcinogenesis (tumor initiation, progression and metastasization) has propelled an incredibly massive number of studies aimed at enquiring its eventual clinical potential in the fight against cancer...
January 11, 2017: Current Protein & Peptide Science
https://www.readbyqxmd.com/read/28074938/sprayable-superhydrophobic-nano-chains-coating-with-continuous-self-jumping-of-dew-and-melting-frost
#11
Shanlin Wang, Wenwen Zhang, Xinquan Yu, Caihua Liang, Youfa Zhang
Spontaneous movement of condensed matter provides a new insight to efficiently improve condensation heat transfer on superhydrophobic surface. However, very few reports have shown the jumping behaviors on the sprayable superhydrophobic coatings. Here, we developed a sprayable silica nano-porous coating assembled by fluorinated nano-chains to survey the condensates' dynamics. The dewdrops were continuously removed by self- and/or trigger-propelling motion due to abundant nano-pores from random multilayer stacking of nano-chains...
January 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28074868/nucleoplasmin-like-domain-of-fkbp39-from-drosophila-melanogaster-forms-a-tetramer-with-partly-disordered-tentacle-like-c-terminal-segments
#12
Małgorzata Kozłowska, Aneta Tarczewska, Michał Jakób, Dominika Bystranowska, Michał Taube, Maciej Kozak, Mariusz Czarnocki-Cieciura, Andrzej Dziembowski, Marek Orłowski, Katarzyna Tkocz, Andrzej Ożyhar
Nucleoplasmins are a nuclear chaperone family defined by the presence of a highly conserved N-terminal core domain. X-ray crystallographic studies of isolated nucleoplasmin core domains revealed a β-propeller structure consisting of a set of five monomers that together form a stable pentamer. Recent studies on isolated N-terminal domains from Drosophila 39-kDa FK506-binding protein (FKBP39) and from other chromatin-associated proteins showed analogous, nucleoplasmin-like (NPL) pentameric structures. Here, we report that the NPL domain of the full-length FKBP39 does not form pentameric complexes...
January 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28072776/gut-microbiome-profiling-tests-propelled-by-customer-demand
#13
Vijay Shankar
No abstract text is available yet for this article.
January 10, 2017: Nature Biotechnology
https://www.readbyqxmd.com/read/28069653/the-molecular-epidemiology-of-pf-k13-mutations-in-senegal-using-targeted-amplicon-deep-sequencing
#14
Eldin Talundzic, Yaye D Ndiaye, Awa B Deme, Christian Olsen, Dhruviben S Patel, Shweta Biliya, Rachel Daniels, Fredrik O Vannberg, Sarah K Volkman, Venkatachalam Udhayakumar, Daouda Ndiaye
The emergence of Plasmodium falciparum (Pf) resistance to artemisinin in Southeast Asia threatens malaria control and elimination activities worldwide. Multiple polymorphisms in the Pf kelch gene found in chromosome 13 (Pfk13) have been associated with artemisinin resistance. Surveillance of potential drug resistance loci within a population that may emerge under increasing drug pressure is an important public health activity. In this context, P. falciparum infections from an observational surveillance study in Senegal were genotyped using targeted amplicon deep sequencing (TADS) for Pfk13 polymorphisms...
January 9, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28068997/absence-of-in-vivo-selection-for-k13-mutations-after-artemether-lumefantrine-treatment-in-uganda
#15
Betty Balikagala, Toshihiro Mita, Mie Ikeda, Miki Sakurai, Shouki Yatsushiro, Nobuyuki Takahashi, Shin-Ichiro Tachibana, Mary Auma, Edward H Ntege, Daisuke Ito, Eizo Takashima, Nirianne Marie Q Palacpac, Thomas G Egwang, Joseph Okello Onen, Masatoshi Kataoka, Eisaku Kimura, Toshihiro Horii, Takafumi Tsuboi
BACKGROUND: Individual drug treatment may select resistant parasites in the human body, a process termed in vivo selection. Some single nucleotide polymorphisms in Plasmodium falciparum chloroquine-resistance transporter (pfcrt) and multidrug resistance gene 1 (pfmdr1) genes have been reportedly selected after artemether-lumefantrine treatment. However, there is a paucity of data regarding in vivo selection of P. falciparum Kelch propeller domain (pfkelch13) polymorphisms, responsible for artemisinin-resistance in Asia, and six putative background mutations for artemisinin resistance; D193Y in ferredoxin, T484I in multiple resistance protein 2, V127M in apicoplast ribosomal protein S10, I356T in pfcrt, V1157L in protein phosphatase and C1484F in phosphoinositide-binding protein...
January 9, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28067229/tubules-of-plant-reoviruses-exploit-tropomodulin-to-regulate-actin-based-tubule-motility-in-insect-vector
#16
Qian Chen, Linghua Zhang, Yanshuang Zhang, Qianzhuo Mao, Taiyun Wei
Plant reoviruses are known to exploit virion-packaging tubules formed by virus-encoding non-structural proteins for viral spread in insect vectors. Tubules are propelled by actin-based tubule motility (ABTM) to overcome membrane or tissue barriers in insect vectors. To further understand which insect factors mediate ABTM, we utilized yeast two-hybrid and bimolecular fluorescence complementation assays to test interactions between tubule protein Pns10 of rice dwarf virus (RDV), a plant reovirus, and proteins of its insect vector, the leafhopper Nephotettix cincticeps...
January 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28067115/macro-porous-hydrogel-scaffolds-for-3-d-cell-culture-and-tissue-engineering
#17
Changjiang Fan, Dong-An Wang
Hydrogels have been promising candidate scaffolds for cell delivery and tissue engineering due to their tissue-like physical properties and capability for homogeneous cell loading. However, the encapsulated cells are generally entrapped and constrained in the submicron- or nano-sized gel networks, seriously limiting cell growth and tissue formation. Meanwhile, the spatially-confined settlement inhibits attachment and spreading of anchorage dependent cells, leading to their apoptosis. In recent years, macro-porous hydrogels have attracted increasing attention in use as cell delivery vehicles and tissue engineering scaffolds...
January 8, 2017: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/28066850/morphology-of-clusters-of-attractive-dry-and-wet-self-propelled-spherical-particle-suspensions
#18
Francisco Alarcón, Chantal Valeriani, Ignacio Pagonabarraga
In order to assess the effect of hydrodynamics in the assembly of active attractive spheres, we simulate a semi-dilute suspension of attractive self-propelled spherical particles in a quasi-two dimensional geometry comparing the case with and without hydrodynamics interactions. To start with, independent of the presence of hydrodynamics, we observe that depending on the ratio between attraction and propulsion, particles either coarsen or aggregate forming finite-size clusters. Focusing on the clustering regime, we characterize two different cluster parameters, i...
January 9, 2017: Soft Matter
https://www.readbyqxmd.com/read/28064147/experimental-and-theoretical-studies-on-stability-of-new-stabilizers-for-n-methyl-p-nitroaniline-derivative-in-cmdb-propellants
#19
Qiufan Tang, Xuezhong Fan, Jizhen Li, Fuqiang Bi, Xiaolong Fu, Lianjie Zhai
Although N-methyl-P-nitroaniline (MNA) was a quite effective stabilizer in composite modified double base (CMDB) propellants, it undergoes crystallization easily from nitroglycerin (NG) during storage. In order to improve its solubility in nitroglycerin (NG) and the stability in propellants, several new stabilizers including N-ethyl-p-nitroaniline (ENA), N-n-propyl-p-nitroaniline (n-PNA), N-i-propyl-p-nitroaniline (i-PNA), N-n-butyl-p-nitroaniline (n-BNA) and N-t-butyl-p-nitroaniline (t-BNA) were designed and synthesized to replace MNA by increasing the carbon chain length...
December 28, 2016: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28058083/simulating-the-hydrodynamics-of-self-propelled-colloidal-clusters-using-stokesian-dynamics
#20
Yousef M F El Hasadi, Martin Crapper
Self-propelled clusters are involved in many technological applications such as in material science and biotechnology, and understanding their interaction with the fluid that surrounds them is of a great importance. We present results of swimming velocity and energy dissipation obtained through Stokesian dynamics simulations of self-propelled clusters. The clusters are of diffusion limited aggregates, consisting of force- and torque-free spherical particles. The number of particles per cluster ranges from 100 to 400, and with two fractal dimensions of 2...
November 2016: Biomicrofluidics
keyword
keyword
114780
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"