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diagnostic cytopathology

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https://www.readbyqxmd.com/read/29665117/digital-versus-traditional-are-diagnostic-accuracy-rates-similar-for-glass-slides-versus-whole-slide-images-in-a-non-gynaecological-external-quality-assurance-setting
#1
Jennifer Ross, Janelle Greaves, Peter Earls, Boaz Shulruf, Simone L Van Es
BACKGROUND: The Royal College of Pathologists of Australasia Quality Assurance Programs introduced virtual microscopy cases into its cytopathology non-gynaecological program after a short pilot phase, to address the challenges of providing a purely glass slide-based external quality assurance program to multiple participants both locally and internationally. The use of whole slide image (WSI) cases has facilitated a more robust program in relation to standardised material and statistical analysis, with access to a wider variety of specimen types and diagnostic entities...
April 17, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29624076/performance-characteristics-of-cerebrospinal-fluid-cytology-an-analysis-of-responses-from-the-college-of-american-pathologists-nongynecologic-cytopathology-education-program
#2
Z Laura Tabatabai, Manon Auger, Rhona J Souers, Lisa Teot, Diane D Davey
CONTEXT: - Cerebrospinal fluid cytology is a critical diagnostic tool for the diagnosis of many conditions affecting the central nervous system. OBJECTIVE: - To assess the performance characteristics of cerebrospinal fluid cytology samples by evaluating participant interpretations within the College of American Pathologists' Nongynecologic Cytopathology Education program. DESIGN: - Participant interpretations (N = 46 264) evaluated in the College of American Pathologists' Nongynecologic Cytopathology Education Program were examined for concordance with the general category and with the reference diagnosis...
April 6, 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29614546/cytologic-diagnosis-of-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-and-its-impact-on-the-risk-of-malignancy-in-the-bethesda-system-for-reporting-thyroid-cytopathology-an-institutional-experience
#3
Milim Kim, Joung Eun Kim, Hyun Jeong Kim, Yul Ri Chung, Yoonjin Kwak, So Yeon Park
Background: This study was performed to analyze cytologic diagnosis of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) and its impact on the risk of malignancy (ROM) in the Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). Materials and Methods: 5549 cases of thyroid fine-needle aspiration cytology (FNAC) diagnosed between 2012 and 2014 were included in this study. Diagnostic categories based on TBSRTC were compared with final surgical diagnoses, and the ROM in each category was calculated both including and excluding NIFTP from the malignant lesions...
April 3, 2018: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/29610616/ovarian-strumal-carcinoid-tumour-case-report
#4
Vesna S Antovska, Milka Trajanova, Iskra Krstevska, Irena Gosheva, Jasmina Chelebieva, Irina Prodanova
BACKGROUND: Ovarian strumal carcinoid is a germ cell tumour characterised by a mixture of thyroid tissue and carcinoid. Ovarian struma is a very rare occurrence with 0.3-1% incidence of all ovarian tumours and 3% of mature teratomas. Primary carcinoid ovarian tumours are still uncommon as a part of mature teratoma or mucinous cystadenoma. There are four major variants of a carcinoid tumour: insular, trabecular, strumal and mucinous. A strumal carcinoid is an unusual form of ovarian teratoma composed of an intimate admixture of thyroid/carcinoid tissues...
March 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29607394/diagnostic-adequacy-and-safety-of-endoscopic-ultrasound-guided-fine-needle-aspiration-in-patients-with-lymphadenopathy-in-a-large-cohort
#5
Rinkesh K Bansal, Narendra S Choudhary, Saurabh K Patle, Mahesh K Gupta, Chitranshu Vashishtha, Gagandeep Kaur, Haimanti Sarin, Rajesh Puri
Background and study aims : The role of endoscopic-ultrasound (EUS) guided fine-needle aspiration (FNA) in patients with lymphadenopathy in terms of diagnostic adequacy and safety in large population is not well defined. The aim of this study was to evaluate diagnostic adequacy and safety of EUS-FNA in patients with lymphadenopathy. Patients and methods:  Retrospective study from October 2010 to September 2015 at tertiary care center in Delhi-NCR. We analyzed data from 1005 EUS- FNAs of lymph nodes...
April 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29605452/efficiency-of-the-bethesda-system-for-thyroid-cytopathology
#6
Ismael Mora-Guzmán, José Luis Muñoz de Nova, Cristina Marín-Campos, José Antonio Jiménez-Heffernan, Juan Julián Cuesta Pérez, Marcos Lahera Vargas, Emma Torres Mínguez, Elena Martín-Pérez
INTRODUCTION: Fine-needle aspiration biopsies are a key tool for preoperative assessment of thyroid nodules, and the Bethesda system is the preferred method to report cytological analysis. The purpose of this study is to assess the efficiency of the Bethesda system to identify the malignancy risk of thyroid nodules. METHODS: Patients who underwent thyroid surgery between June 2010 and June 2017 were included. Samples were classified into 6categories according to rates of malignancy associated with each diagnostic category...
March 28, 2018: Cirugía Española
https://www.readbyqxmd.com/read/29599813/cytopathologist-performed-and-ultrasound-guided-fine-needle-aspiration-cytology-enhances-diagnostic-accuracy-and-avoids-pitfalls-an-overview-of-20-years-of-personal-experience-with-a-selection-of-didactic-cases
#7
REVIEW
Nadir Paksoy, Busra Ozbek
Over the last few decades, fine needle aspiration cytology (FNA) has emerged as a SAFE (Simple, Accurate, Fast, Economical) diagnostic tool based on the morphologic evaluation of cells. The first and most important step in obtaining accurate results from FNA is to procure sufficient and representative material from the lesion and to appropriately transfer this material to the laboratory. Unfortunately, the most important aspect of this task occurs beyond the control of the cytopathologist, a key reason for obtaining unsatisfactory results with FNA...
2018: CytoJournal
https://www.readbyqxmd.com/read/29596039/subclassification-of-bethesda-atypical-and-follicular-neoplasm-categories-according-to-nuclear-and-architectural-atypia-improves-discrimination-of-thyroid-malignancy-risk
#8
Joel Xue Yi Lim, Min En Nga, Dedrick Kok Hong Chan, Wee Boon Tan, Rajeev Parameswaran, Kee Yuan Ngiam
BACKGROUND: Although The Bethesda System for Reporting Thyroid Cytopathology has provided clinicians with a standardized classification scheme for the diagnosis of thyroid fine-needle aspiration cytology (FNAC) specimens, the indeterminate categories of Bethesda III (B3)-atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS)-and Bethesda IV (B4)-follicular neoplasm/suspicious for follicular neoplasm (FN/SFN)-continue to pose challenges with regards to ideal diagnostic and therapeutic management...
March 29, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29595320/thyroid-nodules-and-cancer-in-children-and-adolescents-affected-by-hashimoto-s-thyroiditis
#9
Ji-Hye Won, Ji Ye Lee, Hyun Sook Hong, Sun Hye Jeong
OBJECTIVES: To investigate the rates of thyroid nodules and cancer in pediatric cases of Hashimoto's thyroiditis (HT) in Korea. METHODS: We retrospectively reviewed 89 pediatric and adolescent patients (age, 3-18.0 years) with HT who underwent thyroid ultrasonography (US) at our institution from February 2006 to July 2016. The diagnosis of HT was based on the presence of thyroid autoantibodies. The presence of any thyroid nodules with US and cytopathologic features was analyzed...
March 29, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29594708/endoscopic-ultrasound-guided-fine-needle-aspiration-of-enlarged-adrenals-in-patients-with-pyrexia-of-unknown-origin-a-single-center-experience-of-52-cases
#10
Rinkesh K Bansal, Narendra S Choudhary, Saurabh K Patle, Amit Agarwal, Gagandeep Kaur, Haimanti Sarin, Rajesh Puri
BACKGROUND: Fine-needle aspiration (FNA) of adrenals is needed in patients with pyrexia of unknown origin (PUO) and adrenal enlargement in absence of other diagnostic clues. Adrenals are easily accessible by endoscopic ultrasound (EUS) due to proximity; however, there is no systemic study available on FNA of adrenals in patients with PUO. The aim of this study was to evaluate the diagnostic yield and safety of EUS-FNA of enlarged adrenal in patients with PUO. METHODS: Data was analyzed from October 2010 to September 2016 at a single tertiary care center in northern India...
March 28, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29591914/the-bethesda-system-for-reporting-thyroid-cytopathology-explained-for-practitioners-frequently-asked-questions
#11
Massimo Bongiovanni, Georgios E Papadakis, Nathalie Rouiller, Laura Marino, Faiza Lamine, Bettina Bisig, Sonia Ziadi, Gerasimos P Sykiotis
The recent update of the Bethesda system for reporting thyroid cytology (TBSRTC) is a very important development in the evaluation of thyroid nodules. Clinical experience and scientific literature both show that practitioners performing thyroid FNA are accustomed to basing the clinical management of patients on reports using TBSRTC. Specifically, clinicians are familiar with the per cent risk of malignancy (ROM) corresponding to each TBSRTC diagnostic category (DC), as well as with the respective recommendation for clinical management...
March 28, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29587250/efficacy-of-fine-needle-aspiration-cytology-in-the-diagnosis-of-tuberculous-cervical-lymphadenitis
#12
Soumaya Rammeh, Emna Romdhane, Amira Arfaoui Toumi, Yoldez Houcine, Rym Lahiani, Asma Sassi, Helmi Mardassi, Mamia Ben Salah, Mohamed Ferjaoui
OBJECTIVE: This study assesses the role of fine-needle aspiration cytology (FNAC) in the diagnosis of tuberculous lymphadenitis (TL) in comparison with histology and bacteriology findings. STUDY DESIGN: We undertook a descriptive retrospective study of 937 FNAC specimens from 851 patients with cervical lymph nodes. The FNAC findings were then compared to histopathology and bacteriology. RESULTS: Of the 937 aspirates, the cytopathological diagnoses consisted of 426 (55...
March 27, 2018: Acta Cytologica
https://www.readbyqxmd.com/read/29582676/factors-impacting-the-performance-characteristics-of-bile-duct-brushings-a-clinico-cytopathologic-analysis-of-253-patients
#13
Ezgi Hacihasanoglu, Bahar Memis, Burcin Pehlivanoglu, Vaidehi Avadhani, Alexa A Freedman, Michael M Goodman, N Volkan Adsay, Michelle D Reid
CONTEXT: - Literature on factors impacting bile duct brushings (BDBs) performance characteristics remain limited. OBJECTIVE: - To capture the current state of daily practice with BDB sign-out. DESIGN: - Two hundred fifty-three of 444 BDBs signed out by more than 7 cytopathologists, with histopathologic and/or clinical follow-up of at least 18 months, were examined. RESULTS: - One hundred thirty-five of 253 BDBs (53%) had histologically confirmed malignancies, 22 (9%) had cancer-related deaths, and 96 (38%) were benign...
March 27, 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29579353/northern-italy-in-the-american-south-assessing-interobserver-reliability-within-the-milan-system-for-reporting-salivary-gland-cytopathology
#14
Johnathan M Hollyfield, Siobhan M O'Connor, Susan J Maygarden, Kevin G Greene, Lori R Scanga, Sherry Tang, Leslie G Dodd, Sara E Wobker
BACKGROUND: The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) has been proposed to standardize salivary gland fine-needle aspiration (FNA) diagnoses. This study assessed salivary gland FNA results and risk of malignancy (ROM) rates at the University of North Carolina as well as the interobserver reliability (IOR) of the atypia of undetermined significance (AUS) and salivary gland neoplasm of uncertain malignant potential (SUMP) categories. METHODS: The electronic medical record was searched for FNA cases from 2010 to 2017 with subsequent surgical resections...
March 26, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/29565499/diagnostic-performance-of-endoscopic-ultrasound-guided-fine-needle-aspiration-in-pancreatic-lesions
#15
Q-M Wu, Y-N Guo, Y-Q Xu
OBJECTIVE: This aim of this study is to investigate the diagnostic performance of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in pancreatic lesions. PATIENTS AND METHODS: Patients with pancreatic lesions after CT (or MRI) and EUS-FNA examination were retrospectively enrolled. Cytopathological diagnosis of pancreas tissue were obtained by surgery or EUS-FNA. Clinical follow-up results were used as golden standard for diagnosis of pancreatic lesions...
March 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29565212/more-than-a-decade-of-molecular-diagnostic-cytopathology-leading-diagnostic-and-therapeutic-decision-making
#16
Manuel Salto-Tellez
No abstract text is available yet for this article.
April 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29565206/acquired-resistance-to-tyrosine-kinase-inhibitors-in-non-small-cell-lung-cancers-the-role-of-next-generation-sequencing-on-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-samples
#17
Elena Guerini-Rocco, Antonio Passaro, Chiara Casadio, Valeria Midolo De Luca, Juliana Guarize, Filippo de Marinis, Davide Vacirca, Massimo Barberis
CONTEXT: - Molecular testing is essential for the diagnostic workup of patients with advanced non-small cell lung cancers. Cytology specimens from minimally invasive procedures, such as endobronchial ultrasound-guided transbronchial needle aspiration, are often the only available samples for these patients. The implementation of molecular diagnostic testing, and in particular next-generation sequencing-based testing, on these cytologic specimens is currently an evolving field for lung cytopathology...
April 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29530040/quantitative-evaluation-of-canine-urinary-bladder-transitional-cell-carcinoma-using-contrast-enhanced-ultrasonography
#18
Francesco Macrì, Simona Di Pietro, Cyndi Mangano, Michela Pugliese, Giuseppe Mazzullo, Nicola M Iannelli, Vito Angileri, Simona Morabito, Massimo De Majo
BACKGROUND: In veterinary medicine, contrast-enhanced ultrasonography allowed the accurate quantification of liver, splenic and kidney vascularization in healthy dogs and the differentiation between malignant and benign hepatic, renal, and splenic nodules in dogs and cats based on perfusion patterns. The utility of contrast-enhanced ultrasonography in other applications is still under study. The aim of this study was to develop diagnostic criteria by contrast-enhanced ultrasonography in 8 client-owned adult dogs affected by urinary bladder transitional cell carcinoma with definitive diagnosis made by cytopathologic evaluation after suction biopsy...
March 12, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29528819/idiopathic-granulomatous-mastitis-manifestations-at-multimodality-imaging-and-pitfalls
#19
Cedric W Pluguez-Turull, Jennifer E Nanyes, Cristina J Quintero, Hamza Alizai, Daniel D Mais, Kenneth A Kist, Nella C Dornbluth
Idiopathic granulomatous mastitis (IGM) is a rare benign inflammatory breast entity characterized by lobulocentric granulomas. IGM has a persistent or recurrent disease course and affects parous premenopausal women with a history of lactation. It has also been associated with hyperprolactinemia. The most common clinical sign is a palpable tender mass. However, the nonspecific manifestations and varied demographic features of this condition, as well as the other similar-appearing and superimposed breast entities, pose substantial diagnostic challenges...
March 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29524082/diagnostic-approach-to-fine-needle-aspirations-of-cystic-lesions-of-the-salivary-gland
#20
REVIEW
Liron Pantanowitz, Lester D R Thompson, Esther Diana Rossi
Fine needle aspiration (FNA) has diagnostic and therapeutic value in the management of salivary gland cysts. Rendering an accurate diagnosis from an aspirated salivary gland cyst is challenging because of the broad differential diagnosis, possibility of sampling error, frequent hypocellularity of specimens, morphologic heterogeneity, and overlapping cytomorphology of many cystic entities. To date, there have been no comprehensive review articles providing a practical diagnostic approach to FNA of cystic lesions of salivary glands...
March 9, 2018: Head and Neck Pathology
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