keyword
MENU ▼
Read by QxMD icon Read
search

diagnostic cytopathology

keyword
https://www.readbyqxmd.com/read/28511175/flexible-19-gauge-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-needle-first-experience
#1
Chung Tyan, Priya Patel, Kasia Czarnecka, Daniela Gompelmann, Ralf Eberhardt, Marc Fortin, Paul MacEachern, Christopher A Hergott, Elaine Dumoulin, Alain Tremblay, Samuel V Kemp, Pallav L Shah, Felix J F Herth, Kazuhiro Yasufuku
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a well-established first-line invasive modality for mediastinal lymph node staging in lung cancer patients and in the diagnostic workup of patients with mediastinal adenopathy. With the current 21- and 22-gauge (G) EBUS-TBNA needles, the procedure can be limited by the degree of flexibility in the needle and the size of the lumen in tissue acquisition. OBJECTIVE: We report our initial experience with a first-generation flexible 19-G EBUS-TBNA (Flex 19G; Olympus Respiratory America, Redmond, WA, USA) needle with regards to efficacy and safety...
May 17, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28506417/new-perspectives-in-the-diagnosis-of-thyroid-follicular-lesions
#2
REVIEW
Enke Baldini, Salvatore Sorrenti, Francesco Tartaglia, Antonio Catania, Andrea Palmieri, Daniele Pironi, Angelo Filippini, Salvatore Ulisse
Thyroid nodules are very common, affecting 19%-67% of the adult population. However, about 10% of them harbor a malignant lesion. Consequently, the first aim in their clinical evaluation is to exclude malignancy. Fine-needle aspiration cytology (FNAC) represents the main diagnostic tool for the evaluation of thyroid nodules. However, FNAC has a main diagnostic limit, namely cellular atypias of indeterminate significance, which require surgical excision and histological examination to differentiate benign from malignant lesions...
May 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28497108/a-meta-analysis-of-endoscopic-ultrasound-fine-needle-aspiration-compared-to-endoscopic-ultrasound-fine-needle-biopsy-diagnostic-yield-and-the-value-of-onsite-cytopathological-assessment
#3
REVIEW
Muhammad Ali Khan, Ian S Grimm, Bilal Ali, Richard Nollan, Claudio Tombazzi, Mohammad Kashif Ismail, Todd H Baron
Background The diagnostic yield of endoscopic ultrasound (EUS) guided fine-needle aspiration (FNA) is variable, and partly dependent upon rapid onsite evaluation (ROSE) by a cytopathologist. Second generation fine-needle biopsy (FNB) needles are being increasingly used to obtain core histological tissue samples. Aims Studies comparing the diagnostic yield of EUS guided FNA versus FNB have reached conflicting conclusions. We therefore conducted a systematic review and meta-analysis to compare the diagnostic yield of FNA with FNB, and specifically evaluating the diagnostic value of ROSE while comparing the two types of needles...
May 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28488195/differences-in-clinical-features-between-subcategories-of-atypia-follicular-lesion-of-undetermined-significance
#4
Seong Dong Kim, Seung Hoon Han, Woo-Jin Jeong, Hyojin Kim, Soon Hyun Ahn
Within the Bethesda System for Reporting Thyroid Cytopathology (TBSRTC), category III (atypia or follicular lesion of undetermined significance (AUS/FLUS)) comprises specimens with heterogeneous features and the need for subcategorization has been reported. We compared the clinical features of two subgroups from within the category of AUS/FLUS to determine precise guidelines for clinicians who explain the results of fine-needle aspiration (FNA) to patients. Retrospective review was performed including data from all patients who underwent FNA with results reported as AUS/FLUS at a single tertiary hospital from January 2010 to August 2014...
May 9, 2017: Endocrine Pathology
https://www.readbyqxmd.com/read/28474649/endobronchial-ultrasound-guided-transbronchial-needle-aspiration-in-diagnosing-mediastinal-lymphadenopathy
#5
Tanushree Gahlot, Ujjwal Parakh, Kusum Verma, Bobby Bhalotra, Neeraj Jain
CONTEXT: The diagnosis of mediastinal lymphadenopathy is always a challenge. There always a need of a technique that is highly accurate as well as safe for diagnosis the same. AIMS: The aim of the study is to assess the clinical usefulness and safety profile of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in diagnosing the patients with mediastinal lymphadenopathy. SETTINGS AND DESIGN: This was an observational prospective study...
May 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28469320/a-rare-tumor-of-salivary-gland-diagnostic-dilemma-on-fine-needle-aspiration-cytology
#6
Charu Agarwal, Manju Kaushal, Minakshi Bhardwaj
Salivary gland cytopathology is a diagnostically challenging area with overlapping cytomorphological features between benign, malignant, and metastatic tumors. We report the case of 45-year-old male who presented with two swellings in right retroauricular and infraauricular region along with a palpable single right cervical lymph node. On ultrasonography of the neck, a possibility of malignant lesion was given. Contrast enhanced computed tomography of the head showed a large well-defined space occupying lesion in right temporooccipital region eroding the skull bone with both extra and intracranial extension...
April 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28467214/evaluation-of-the-afirma-gene-expression-classifier-in-repeat-indeterminate-thyroid-nodules
#7
Grant Harrison, Julie Ann Sosa, Xiaoyin Jiang
CONTEXT: - Molecular testing in indeterminate thyroid nodules is a rapidly evolving field with variable reported outcomes. OBJECTIVE: - To report our experience at a tertiary thyroid referral center with the Afirma Gene Expression Classifier (Veracyte, San Francisco, California) in repeat fine-needle aspirations of thyroid nodules with a previous indeterminate cytologic result. DESIGN: - Results of cytopathology and the Afirma test were collected from August 2013 to March 2015, as were diagnoses from surgical resection when performed...
May 3, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28450086/kras-mutation-testing-on-all-non-malignant-diagnosis-of-pancreatic-endoscopic-ultrasound-guided-fine-needle-aspiration-biopsies-improves-diagnostic-accuracy
#8
Elena Trisolini, Elia Armellini, Alessia Paganotti, Claudia Veggiani, Cristina Bozzola, Milo Frattini, Corinna Pizio, Giuseppe Mancuso, Silvano Andorno, Renzo Boldorini
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is the procedure of choice for the cytologic diagnosis of pancreatic masses. The specificity of EUS-FNA approaches 100%, but the sensitivity is still low, and the high rate of indeterminate (atypical and suspicious) and false-negative results needs improvement. KRAS gene is frequently mutated in pancreatic ductal adenocarcinoma (PDAC) (up to 90%), and mutation analysis of KRAS has been proposed as diagnostic biomarker of PDAC. In most laboratories, KRAS mutation testing is performed by Sanger sequencing or real time-quantitative polymerase chain reaction (RT-qPCR), but these methods may give false-negative results in routine samples, mainly due to low cellularity...
April 24, 2017: Pathology
https://www.readbyqxmd.com/read/28445876/impact-of-the-reclassification-of-the-non-invasive-follicular-variant-of-papillary-carcinoma-as-benign-on-the-malignancy-risk-of-the-bethesda-system-for-reporting-thyroid-cytopathology-a-meta-analysis-study
#9
Lester J Layfield, Zubair W Baloch, Magda Esebua, Rohini Kannuswamy, Robert L Schmidt
OBJECTIVES: The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) established diagnostic categories for cytologic specimens of the thyroid. Each category was associated with an estimated risk of malignancy. Recently, the non-invasive follicular variant of papillary thyroid carcinoma has been reclassified as benign. This reclassification may alter the malignancy risk of TBSRTC diagnostic categories. STUDY DESIGN: A literature search was made for all studies investigating the effect of reclassification of some non-invasive follicular variant papillary thyroid carcinomas as benign on the malignancy risk associated with TBSRTC categories...
April 27, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28407624/risk-of-malignancy-and-risk-of-neoplasia-in-the-bethesda-indeterminate-categories-study-on-4-532-thyroid-fine-needle-aspirations-from-a-single-institution-in-india
#10
Swati Mahajan, Radhika Srinivasan, Arvind Rajwanshi, Bishan Radotra, Naresh Panda, Pranab Dey, Nalini Gupta, Raje Nijhawan
OBJECTIVES: To determine the frequency of category 3 (atypia of undetermined significance [AUS]/follicular lesion of undetermined significance [FLUS]), category 4 (follicular neoplasm), and category 5 (suspicious for malignancy) of The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC), the risk of malignancy (ROM) and the risk of neoplasia (RON) in these categories. STUDY DESIGN: A retrospective 6-year audit of 4,532 thyroid fine-needle aspirations (FNA) reported as per the TBSRTC from a single institution with cytohistological correlation in 335 cases...
2017: Acta Cytologica
https://www.readbyqxmd.com/read/28407623/fine-needle-aspiration-of-langerhans-cell-histiocytosis-a-cytopathologic-study-of-37-cases
#11
Jen-Fan Hang, Momin T Siddiqui, Syed Z Ali
OBJECTIVE: Langerhans cell histiocytosis (LCH) is an uncommon neoplasm of dendritic cells and predominantly occurs in children and young adults. The study aims to evaluate cytopathologic features and current diagnostic concepts in a large series of LCH on fine needle aspiration (FNA). STUDY DESIGN: We retrospectively searched the pathology archives of The Johns Hopkins Hospital (JHH) and Emory University Hospital (EUH) to identify all FNA cases diagnosed as LCH in a period of 21 years...
2017: Acta Cytologica
https://www.readbyqxmd.com/read/28397450/bethesda-system-in-the-evaluation-of-thyroid-nodules-review
#12
REVIEW
Marta Wesoła, Michał Jeleń
Fine needle aspiration (FNA) biopsy is an important and widely accepted method used in the diagnosis of patients with thyroid nodules.The lack of consistency in reporting FNA taken from the thyroid gland has led to divergences in the calculation of the sensitivity and specificity of the method. Discrepancies depend on what was considered to be true or false negative/positive. This resulted in confusion among doctors, who had to decide how to manage the patient with constantly changing positive or negative results of the FNA...
January 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28388017/adequacy-criteria-for-thyroid-fna-evaluated-by-thinprep-slides-only
#13
Marina Vivero, Andrew A Renshaw, Jeffrey F Krane
BACKGROUND: Adequacy criteria for thyroid fine-needle aspiration (FNA) recommended by The Bethesda System for Reporting Thyroid Cytopathology (TBS) were developed with smears, but they are commonly applied to ThinPreps (TPs). This study evaluated adequacy in TPs at different diagnostic thresholds. METHODS: All FNA procedures performed between 2010 and 2015 with matched surgical specimens were analyzed. Cell counts and cytological features were evaluated in all initially nondiagnostic (ND) cases...
April 7, 2017: Cancer
https://www.readbyqxmd.com/read/28371507/reporting-of-fine-needle-aspiration-fna-specimens-of-salivary-gland-lesions-a-comprehensive-review
#14
REVIEW
Shuanzeng Wei, Lester J Layfield, Virginia A LiVolsi, Kathleen T Montone, Zubair W Baloch
Currently, there is no uniform classification scheme available for reporting of salivary gland fine-needle aspiration (FNA) specimens. Recently, an International group of pathologists has recommended a tiered classification scheme for reporting of salivary gland FNA results known as the "Milan System for Reporting Salivary Gland Cytopathology (MSRSGC)." We performed a comprehensive review of the published literature on FNA of salivary gland lesions by employing the diagnostic categories of the MSRSGC to evaluate their reliability in the management of salivary gland lesions...
March 31, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28345284/role-of-fine-needle-aspiration-cytology-in-the-diagnosis-of-a-rare-case-of-a-poorly-differentiated-synovial-sarcoma-with-rhabdoid-features-including-treatment-implications
#15
Bharat Rekhi, Omshree Shetty, Mukta Ramadwar, Venkatesh Rangarajan, Jyoti Bajpai
Synovial sarcoma is a high-grade, soft tissue sarcoma that is relatively chemosensitive. Its exact diagnosis is crucial, including differentiation from its closest diagnostic mimic, ie, Ewing sarcoma, in view of different treatment options, including chemotherapy regimens, for both these tumors. A 15-year-old girl presented with a recurrent soft tissue mass in her right popliteal region, which was diagnosed as Ewing sarcoma, based on positive immunoexpression of MIC2/CD99, Fli1 and negative expression of LCA and desmin...
March 27, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28331530/kras-detection-on-archival-cytological-smears-by-the-novel-fully-automated-polymerase-chain-reaction-based-idylla-mutation-test
#16
Caterina De Luca, Elena Vigliar, Melania d'Anna, Pasquale Pisapia, Claudio Bellevicine, Umberto Malapelle, Giancarlo Troncone
BACKGROUND: Molecular techniques are relevant to modern cytopathology, but their implementation is difficult without molecular expertise and infrastructure. The assessment of KRAS mutational status on cytological preparations may be useful either to refine uncertain diagnoses on pancreatic aspirates or to yield predictive information to plan targeted treatment of metastatic colorectal cancer (mCRC). The novel test Idylla™ enables fully automated KRAS genotyping in approximately 2 h, even in less experienced hands...
2017: CytoJournal
https://www.readbyqxmd.com/read/28280507/fine-needle-aspiration-of-thyroid-nodules-using-the-bethesda-system-for-reporting-thyroid-cytopathology-an-institutional-experience-in-a-rural-setting
#17
Aili Guo, Yuuki Kaminoh, Terra Forward, Frank L Schwartz, Scott Jenkinson
Background. Fine needle aspiration (FNA) remains the first-line diagnostic in management of thyroid nodules and reduces unnecessary surgeries. However, it is still challenging since cytological results are not always straightforward. This study aimed to examine the results of thyroid FNA using the Bethesda system for reporting thyroid cytopathology (TBSRTC) to establish the level of accuracy of FNA procedures in a rural practice setting. Method. A retrospective chart review was conducted on existing thyroid FNA performed in a referral endocrine center between December 2011 and November 2015...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28261993/carcinoma-ex-pleomorphic-adenoma-a-diagnostic-challenge-on-cytology
#18
Kanika Singh, Charu Agarwal, Mukta Pujani, Pragya Verma, Varsha Chauhan
Carcinoma ex pleomorphic adenoma (Ca ex PA) is a malignant neoplasm arising from primary or recurrent benign pleomorphic adenoma. It is rare with an annual incidence rate of 0.17 tumors per million. Histopathology remains the gold standard for the diagnosis of Ca ex PA, with only a handful of cases reported on cytology. In our case a 66-year-old male presented with the right parotid mass for 5 years rapidly increasing for the last 3 months. Fine needle aspiration cytology (FNAC) smears showed malignant tumor cells in clusters along with benign myoepithelial cells in chondromyxoid background...
March 6, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28259878/diagnostic-accuracy-of-fine-needle-aspiration-in-thyroid-nodules-arising-in-patients-with-graves-disease
#19
Jen-Fan Hang, Mohammed T Lilo, Justin A Bishop, Syed Z Ali
OBJECTIVE: Cytopathologic interpretation in Graves disease (GD) is considered challenging due to significant cellular atypia. STUDY DESIGN: We retrospectively identified 55 fine needle aspirations (FNAs) from 43 patients with GD that subsequently underwent thyroidectomy from 1995 to 2016. RESULTS: There were 5 patients with papillary thyroid carcinoma (PTC) and 4 with follicular adenoma (FA). Of the 5 patients with PTC, FNA was interpreted as PTC in 3, atypia of undetermined significance (AUS) in 1, and adenomatoid nodule (AN) in 1 (with a 0...
2017: Acta Cytologica
https://www.readbyqxmd.com/read/28248012/-cytological-evaluation-of-urothelial-damage-in-extracorporeal-shock-wave-lithotripsy
#20
A M Grabsky, E V Manukyan, A A Muradyan
INTRODUCTION: The study proposed a technique for early detection of the damaging effect of shock waves on the urinary tract tissues, for monitoring the state of urothelial cells in the early post-procedure period and choosing an adequate method for preventing and managing possible complications. MATERIALS AND METHODS: The study analyzed the urine samples of 300 patients aged 20 to 50 years, who for the first time underwent ESWL for kidney stones. The urine sediment smears were fixed in the May-Grunwald stain and stained with azure eosin solution according to Pappenheim...
November 2016: Urologii︠a︡
keyword
keyword
114760
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"