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https://www.readbyqxmd.com/read/28426126/actinomyces-in-pregnancy-a-review-of-the-literature
#1
Sarah M Estrada, Everett F Magann, Peter G Napolitano
Importance: Actinomyces is commonly found in many areas of the body where it derives a benefit without harming the host. When it does infect the host during pregnancy, is that infection a threat to the obstetric patient and does that infection cause adverse pregnancy outcomes? Objective: The aim of this study was to review what is known about Actinomyces infections and the impact of an Actinomyces infection on pregnancy outcomes. Evidence Acquisition: A PubMed search was undertaken with the search years unlimited to April 1, 2016, and restricted to articles in English...
April 2017: Obstetrical & Gynecological Survey
https://www.readbyqxmd.com/read/28425250/retrospective-analysis-of-maternal-fetal-and-neonatal-outcomesof-intrahepatic-cholestasis-of-pregnancy-at-gazi-university
#2
Berrin Günaydin, Merih Bayram, Melis Altuğ, Semra Cevher, Nuray Bozkurt
BACKGROUND/AIM: Maternal, fetal, and neonatal outcomes in parturients with intrahepatic cholestasis of pregnancy (ICP) have been retrospectively documented. We aimed to present pregnancy outcomes of parturients with ICP who underwent delivery. The study was conducted during a 1-year period. MATERIALS AND METHODS: After ethics committee approval, data from 1 January to 31 December 2015 were collected to identify parturients with ICP. RESULTS: Ten out of 37 patients underwent normal spontaneous vaginal delivery (NSVD), and the remaining 27 parturients underwent cesarean section (CS)...
April 18, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28407853/effects-of-environmental-enrichment-on-reproductive-performance-and-quantity-and-morphology-of-cumulus-oocyte-complexes-obtained-from-rattus-norvegicus
#3
Joana Fisch, Iáskara Vieira de Oliveira, Juliana Fank, Lia Mara Gomes Paim, Marília Remuzzi Zandoná, Eliana Franco Lopes, Fernanda Bastos de Mello, Alexandre Tavares Duarte de Oliveira
Several researchers have observed that environmental enrichment (EE) can be effective in reducing stressful conditions and abnormal behavior and may provide better reproductive performance in rodents. In this context, this study aimed to evaluate the reproductive performance of Wistar rats reared in three different housing conditions. Animals were separated into breeding pairs, one pair per cage and pairs randomly assigned to three experimental groups (ten couples per group): control group were provided cages without any environmental enrichment; PVC group with PVC pipe; and cardboard roll group with a commercially available cardboard tube...
May 2017: Theriogenology
https://www.readbyqxmd.com/read/28404574/parasitic-infections-in-pregnancy-decrease-placental-transfer-of-anti-pneumococcal-antibodies
#4
Noah D McKittrick, David M Vu, Indu Malhotra, Charles H King, Francis Mutuku, A Desiree LaBeaud
Many factors can influence maternal placental antibody transfer to the fetus, which confers important immune protection to the newborn infant. However, little is known about the effect of maternal parasitic infection on placental antibody transfer. To investigate this, we selected, from a parent study of 576 pregnant Kenyan women, four groups of women with term deliveries (≥37 weeks), including uninfected women (N=30) and women with solo infections of malaria (N=30), hookworm (N=30), or schistosomiasis (N=10)...
April 12, 2017: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/28402697/the-prenatal-distress-measure-adaptation-of-the-postpartum-distress-measure-for-a-prenatal-sample
#5
Niela M Hirsch, Randy Fingerhut, Kelly C Allison
BACKGROUND: Pregnancy is a significant transition period for women that can be markedly stressful. The presence of elevated depressed mood and anxiety during pregnancy places mothers, fetuses, and neonates at greater risk for developing biological and psychological difficulties. It appears that no general measures of distress currently exist that can be used to screen for both prenatal anxiety and mood. MATERIALS AND METHODS: This study explores the applicability of postpartum distress measure (PDM), a validated general distress postpartum screening tool, in a prenatal sample...
April 12, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28399813/the-netherlands-chlamydia-cohort-study-neccst-protocol-to-assess-the-risk-of-late-complications-following-chlamydia-trachomatis-infection-in-women
#6
B M Hoenderboom, A A M van Oeffelen, B H B van Benthem, J E A M van Bergen, N H T M Dukers-Muijrers, H M Götz, C J P A Hoebe, A A Hogewoning, F R M van der Klis, D van Baarle, J A Land, M A B van der Sande, M G van Veen, F de Vries, S A Morré, I V F van den Broek
BACKGROUND: Chlamydia trachomatis (CT), the most common bacterial sexually transmitted infection (STI) among young women, can result in serious sequelae. Although the course of infection is often asymptomatic, CT may cause pelvic inflammatory disease (PID), leading to severe complications, such as prolonged time to pregnancy, ectopic pregnancy, and tubal factor subfertility. The risk of and risk factors for complications following CT-infection have not been assessed in a long-term prospective cohort study, the preferred design to define infections and complications adequately...
April 11, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28396535/pregnancy-reprograms-large-conductance-ca-2-activated-k-channel-in-uterine-arteries-roles-of-ten-eleven-translocation-methylcytosine-dioxygenase-1-mediated-active-demethylation
#7
Xiang-Qun Hu, Chiranjib Dasgupta, Man Chen, Daliao Xiao, Xiaohui Huang, Limin Han, Shumei Yang, Zhice Xu, Lubo Zhang
The large-conductance Ca(2+)-activated K(+) (BKCa) channel is of critical importance in pregnancy-mediated increase in uterine artery vasodilation and blood flow. The present study tested the hypothesis that active DNA demethylation plays a key role in pregnancy-induced reprogramming and upregulation of BKCa channel β1 subunit (BKβ1) in uterine arteries. Uterine arteries were isolated from nonpregnant and near-term pregnant sheep. Pregnancy significantly increased the expression of ten-eleven translocation methylcytosine dioxygenase 1 (TET1) in uterine arteries...
April 10, 2017: Hypertension
https://www.readbyqxmd.com/read/28395793/visceral-aneurysms-old-paradigms-new-insights
#8
REVIEW
M J E van Rijn, S Ten Raa, J M Hendriks, H J M Verhagen
True visceral artery aneurysms (VAAs) are a rare entity with an incidence of 0.01-2%. The risk of rupture varies amongst the different types of VAAs and is higher for pseudo aneurysms compared with true aneurysms. Size, growth, symptoms, underlying disease, pregnancy and liver transplantation have all been associated with increased risk of rupture. Mortality rates after rupture are around 25%. The splenic artery is most commonly affected and the etiology is predominantly atherosclerosis. Open repair can be done by simple ligation or reconstruction of the artery, while endovascular options include embolization or using a stent graft...
February 2017: Best Practice & Research. Clinical Gastroenterology
https://www.readbyqxmd.com/read/28384909/immediate-outcome-of-balloon-mitral-valvuloplasty-with-jomiva-balloon-during-pregnancy
#9
Shanmuga Sundaram Rathakrisnnan, Ramona Ramasamy, Tamilarasu Kaliappan, Rajendiran Gopalan, Ramasmy Palanimuthu, Premkrishna Anandhan
INTRODUCTION: Rheumatic mitral stenosis is the most common Valvular Heart Disease encountered during pregnancy. Balloon Mitral Valvuloplasty (BMV) is one of the treatment option available if the symptoms are refractory to the medical management and the valve anatomy is suitable for balloon dilatation. BMV with Inoue balloon is the most common technique being followed worldwide. Over the wire BMV is a modified technique using Joseph Mitral Valvuloplasty (JOMIVA) balloon catheter which is being followed in certain centres...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28380144/-postpartum-follow-up-of-women-s-health
#10
Maria Suely Medeiros Corrêa, Katia Virginia de Oliveira Feliciano, Evelyne Nascimento Pedrosa, Ariani Impieri de Souza
This study focused on perceptions and practices in postpartum follow-up of women's health. The article is part of a larger qualitative study based on Gadamer, from October 2012 to September 2013 in Recife, Pernambuco State, Brazil, with participant observation and semi-structured interviews. Participation included the family health team (a physician, nurse, and five health agents) and ten women (18 years or older, recruited in the last trimester of pregnancy, and receiving prenatal care with the family health team)...
April 3, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28369907/who-is-and-isn-t-having-babies-with-down-syndrome-in-western-sydney-a-ten-year-hospital-cohort-study
#11
Rebecca M Moses, James H W Brown, Dale C Wright, Hayley Diplock, Sarah J Melov, Therese Mary McGee
BACKGROUND: Screening for Down syndrome (DS) is a key component of antenatal care, recommended to be universally offered to women irrespective of age or background. Despite this, the diagnosis of DS is often not made until the neonatal period. AIMS: To retrospectively describe and compare the differences in populations with an antenatal diagnosis (AD) and neonatal diagnosis (ND) of DS and to explore why an antenatal diagnosis was not made. MATERIALS AND METHODS: The cohorts were women cared for at Westmead Hospital whose pregnancy received a diagnosis of DS between 2006 and 2015...
March 29, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28369651/placental-disposition-and-effects-of-crizotinib-an-ex-vivo-study-in-the-isolated-dual-side-perfused-human-cotyledon
#12
Gaby A M Eliesen, Petra van den Broek, Jeroen J van den Heuvel, Albert Bilos, Jeanne Pertijs, Joris van Drongelen, Frans G M Russel, R Greupink
Background: Tyrosine kinase inhibitors (TKIs) play an important role in cancer pharmacotherapy, yet there is limited data on their use during pregnancy. We studied placental disposition and placental toxicity of crizotinib, a TKI used to treat non-small cell lung cancer. Material and methods: Term placentas were perfused for three hours with crizotinib (1µM) using the ex vivo dual-side cotyledon perfusion technique. Interference of TKIs with trophoblast viability was studied using BeWo cells...
March 24, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28369513/identification-and-characterization-of-aurora-kinase-b-and-c-variants-associated-with-maternal-aneuploidy
#13
Alexandra L Nguyen, Diego Marin, Anbo Zhou, Amanda S Gentilello, Evan M Smoak, Zubing Cao, Anastasia Fedick, Yujue Wang, Deanne Taylor, Richard T Scott, Jinchuan Xing, Nathan Treff, Karen Schindler
STUDY QUESTION: Are single nucleotide variants (SNVs) in Aurora kinases B and C associated with risk of aneuploid conception? SUMMARY ANSWER: Two SNVs were found in patients with extreme aneuploid concepti rates with respect to their age; one variant, AURKC p.I79V, is benign, while another, AURKB p.L39P, is a potential gain-of-function mutant with increased efficiency in promoting chromosome alignment. WHAT IS KNOWN ALREADY: Maternal age does not always predict aneuploidy risk, and rare gene variants can be drivers of disease...
March 25, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28355524/ten-years-on-a-review-of-medical-terminations-of-pregnancy-performed-in-a-sexual-health-clinic
#14
Sandra G Downing, Colette Cashman, Darren B Russell
Background: Access to medical termination of pregnancy (MToP) services in regional Queensland remains inadequate and it is still possible for women and providers to be criminally prosecuted for accessing or providing abortion. Cairns Sexual Health Service (CSHS) has been providing medical terminations of pregnancy for 10 years, demonstrating that this service can be safely and successfully integrated into a primary healthcare setting. Methods: A retrospective audit of MToPs performed between 2011 and 2015 was conducted to follow on from our previously reported audit covering 2006-09...
March 30, 2017: Sexual Health
https://www.readbyqxmd.com/read/28349516/outcomes-and-predictive-tests-from-a-dedicated-specialist-clinic-for-women-at-high-risk-of-preterm-labour-a-ten-year-audit
#15
Kelly Hughes, Shirlene Sim, Alina Roman, Kasia Michalak, Stefan Kane, Penelope Sheehan
BACKGROUND: Preterm birth continues to be a major cause of infant morbidity and mortality worldwide, but advances have recently been made in its prediction and prevention. A short cervix (<25 mm) in the second trimester on transvaginal ultrasound scan and fetal fibronectin are important predictive tests. For over ten years, the Preterm Labour Clinic at the Royal Women's Hospital, Melbourne, Australia has provided care for women at high risk of preterm birth, including those with a previous preterm birth, previous cervical surgery, uterine malformation or incidental finding of short cervix at routine ultrasound...
March 28, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28341527/the-relationship-of-maternal-prepregnancy-body-mass-index-and-pregnancy-weight-gain-to-neurocognitive-function-at-age-10-years-among-children-born-extremely-preterm
#16
Elizabeth T Jensen, Jelske W van der Burg, Thomas M O'Shea, Robert M Joseph, Elizabeth N Allred, Tim Heeren, Alan Leviton, Karl C K Kuban
OBJECTIVE: To assess the association between maternal prepregnancy body mass index and adequacy of pregnancy weight gain in relation to neurocognitive function in school-aged children born extremely preterm. STUDY DESIGN: Study participants were 535 ten-year-old children enrolled previously in the prospective multicenter Extremely Low Gestational Age Newborns cohort study who were products of singleton pregnancies. Soon after delivery, mothers provided information about prepregnancy weight...
March 21, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28336163/a-meta-analysis-of-the-impact-of-human-leukocyte-antigen-g-on-the-outcomes-of-ivf-icsi
#17
Ziru Niu, Liangyi Wang, Ronald T K Pang, Yifan Guo, William S B Yeung, Yuanqing Yao
This analysis was performed to determine whether the presence of soluble human leukocyte antigen-G (sHLA-G) in embryo culture medium is predictive of clinical outcomes in IVF treatment. The outcomes of implantation, clinical pregnancy, multiple pregnancy and miscarriage, between groups with and without sHLA-G in embryo culture media, were analysed. Fifteen studies with a total of 6170 cases were included. Ten of them were prospective studies while five were retrospective studies. Embryo culture media with sHLA-G were associated with significantly higher implantation rate and clinical pregnancy rate when compared with those without; the odd ratios (ORs) were 2...
March 14, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28333034/treatment-of-thin-endometrium-with-autologous-platelet-rich-plasma-a-pilot-study
#18
Shahrzad Zadehmodarres, Saghar Salehpour, Nasrin Saharkhiz, Leila Nazari
Endometrium is one of the main factors in pregnancy. During assisted reproductive technology (ART) treatments, some cycles are cancelled due to inadequate endometrial growth. This study was conducted to evaluate the effectiveness of platelet-rich plasma (PRP) in the treatment of thin endometrium. Ten patients with history of inadequate endometrial growth in frozen-thawed embryo transfer (FET) cycles were recruited into the study. Intrauterine infusion of PRP was performed. Endometrial thickness was assessed...
February 1, 2017: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/28332092/the-spectrum-of-neuropathological-changes-associated-with-congenital-zika-virus-infection
#19
Leila Chimelli, Adriana S O Melo, Elyzabeth Avvad-Portari, Clayton A Wiley, Aline H S Camacho, Vania S Lopes, Heloisa N Machado, Cecilia V Andrade, Dione C A Dock, Maria Elisabeth Moreira, Fernanda Tovar-Moll, Patricia S Oliveira-Szejnfeld, Angela C G Carvalho, Odile N Ugarte, Alba G M Batista, Melania M R Amorim, Fabiana O Melo, Thales A Ferreira, Jacqueline R L Marinho, Girlene S Azevedo, Jeime I B F Leal, Rodrigo F Madeiro da Costa, Stevens Rehen, Monica B Arruda, Rodrigo M Brindeiro, Rodrigo Delvechio, Renato S Aguiar, Amilcar Tanuri
A major concern associated with ZIKV infection is the increased incidence of microcephaly with frequent calcifications in infants born from infected mothers. To date, postmortem analysis of the central nervous system (CNS) in congenital infection is limited to individual reports or small series. We report a comprehensive neuropathological study in ten newborn babies infected with ZIKV during pregnancy, including the spinal cords and dorsal root ganglia (DRG), and also muscle, pituitaries, eye, systemic organs, and placentas...
March 22, 2017: Acta Neuropathologica
https://www.readbyqxmd.com/read/28326560/sex-chromosome-aneuploidy-detection-by-non-invasive-prenatal-testing-helpful-or-hazardous
#20
Rosemary E Reiss, Marie Discenza, Judith Foster, Lori Dobson, Louise Wilkins-Haug
OBJECTIVES: To assess the incidence of sex chromosome aneuploidy (SCA) predicted by non-invasive prenatal testing (NIPT), assess test performance, and compare it with nuchal translucency (NT) screening among patients seen in our prenatal diagnosis center. METHODS: We identified suspected cases of SCA by reviewing results from all NIPT samples sent from our center to commercial laboratories offering analysis by cell-free DNA between December 1, 2012 to July 31, 2015...
March 21, 2017: Prenatal Diagnosis
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