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https://www.readbyqxmd.com/read/28088779/comprehensive-proteome-analysis-of-lysosomes-reveals-the-diverse-function-of-macrophages-in-immune-responses
#1
Yanpan Gao, Yanyu Chen, Shaohua Zhan, Wenhao Zhang, Feng Xiong, Wei Ge
Phagocytosis and autophagy in macrophages have been shown to be essential to both innate and adaptive immunity. Lysosomes are the main catabolic subcellular organelles responsible for degradation and recycling of both extracellular and intracellular material, which are the final steps in phagocytosis and autophagy. However, the molecular mechanisms underlying lysosomal functions after infection remain obscure. In this study, we conducted a quantitative proteomics analysis of the changes in constitution and glycosylation of proteins in lysosomes derived from murine RAW 264...
January 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28087753/acquired-central-hypoventilation-following-listeria-monocytogenes-rhombencephalitis
#2
Sandrine H Launois, Natalia Siyanko, Marie Joyeux-Faure, Renaud Tamisier, Jean-Louis Pepin
No abstract text is available yet for this article.
January 13, 2017: Thorax
https://www.readbyqxmd.com/read/28087538/bcap-inhibits-proliferation-and-differentiation-of-myeloid-progenitors-in-the-steady-state-and-during-demand-situations
#3
Jeffrey M Duggan, Matthew B Buechler, Rebecca M Olson, Tobias M Hohl, Jessica A Hamerman
B cell adaptor for PI3-kinase (BCAP) is a signaling adaptor expressed in mature hematopoietic cells including monocytes and neutrophils. Here we investigated the role of BCAP in the homeostasis and development of these myeloid lineages. BCAP(-/-) mice had more bone marrow (BM) monocytes than WT mice, and in mixed WT:BCAP(-/-) BM chimeras, monocytes and neutrophils skewed towards BCAP(-/-) origin, showing a competitive advantage for BCAP(-/-) myeloid cells. BCAP was expressed in bone marrow hematopoietic progenitors, including LSK (Lineage(-)Sca1(+)cKit(+)), CMP (Common Myeloid Progenitor) and GMP (Granulocyte/Macrophage Progenitor) cells...
January 13, 2017: Blood
https://www.readbyqxmd.com/read/28074026/promyelocytic-leukemia-protein-pml-controls-listeria-monocytogenes-infection
#4
David Ribet, Valérie Lallemand-Breitenbach, Omar Ferhi, Marie-Anne Nahori, Hugo Varet, Hugues de Thé, Pascale Cossart
: The promyelocytic leukemia protein (PML) is the main organizer of stress-responsive subnuclear structures called PML nuclear bodies. These structures recruit multiple interactors and modulate their abundance or their posttranslational modifications, notably by the SUMO ubiquitin-like modifiers. The involvement of PML in antiviral responses is well established. In contrast, the role of PML in bacterial infection remains poorly characterized. Here, we show that PML restricts infection by the pathogenic bacterium Listeria monocytogenes but not by Salmonella enterica serovar Typhimurium...
January 10, 2017: MBio
https://www.readbyqxmd.com/read/28073081/antibacterial-effect-of-405%C3%A2-5nm-light-emitting-diode-illumination-against-escherichia-coli-o157-h7-listeria-monocytogenes-and-salmonella-on-the-surface-of-fresh-cut-mango-and-its-influence-on-fruit-quality
#5
Min-Jeong Kim, Chee Hwa Tang, Woo Suk Bang, Hyun-Gyun Yuk
To investigate a potential of 405±5nm light emitting diode (LED) as a novel technology for food preservation, the antibacterial effect of 405±5nm LED on Escherichia coli O157:H7, Listeria monocytogenes, and Salmonella spp. on the surface of fresh-cut mango and its influence on fruit quality were evaluated at different storage temperatures. LED-illumination inactivated 1.0-1.6 logCFU/cm(2) of populations at 4 and 10°C for 36-48h (total dose, 2.6-3.5kJ/cm(2)) regardless of bacterial species, while those on non-illuminated mange remained unchanged or slightly increased during storage...
December 30, 2016: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28073080/impact-of-environmental-factors-on-the-culturability-and-viability-of-listeria-monocytogenes-under-conditions-encountered-in-food-processing-plants
#6
Anaïs Overney, Joséphine Jacques-André-Coquin, Patricia Ng, Brigitte Carpentier, Laurent Guillier, Olivier Firmesse
The ability of Listeria monocytogenes to adhere to and persist on surfaces for months or even years may be responsible for its transmission from contaminated surfaces to food products. Hence the necessity to find effective means to prevent the establishment of L. monocytogenes in food processing environments. The aim of this study was to assess, through a fractional experimental design, the environmental factors that could affect the survival of L. monocytogenes cells on surfaces to thereby prevent the persistence of this pathogen in conditions mimicking those encountered in food processing plants: culture with smoked salmon juice or meat exudate, use of two materials with different hygiene status, biofilm of L...
December 21, 2016: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28071802/essential-oils-against-pathogen-and-spoilage-microorganisms-of-fruit-juices-use-of-versatile-antimicrobial-delivery-systems
#7
Valentina Trinetta, Mark T Morgan, John N Coupland, Umut Yucel
Essential oils (EO) are increasingly used as natural antimicrobial compounds, however the effect of delivery system to enhance their antimicrobial activity has not been widely studied. Limonene (0 to 10 μL/mL) was added to microbial suspensions (∼10(5) CFU/mL) of selected foodborne pathogens (Listeria monocytogenes Scott A, Salmonella enterica Typhimurium, Escherichia coli and Staphylococcus aureus), and spoilage microorganisms (Lactobacillus plantarum, Saccharomyces cerevisiae, and Candida albicans). S...
January 10, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28068841/listeria-monocytogenes-behaviour-and-quality-attributes-during-sausage-storage-affected-by-sodium-nitrite-sodium-lactate-and-thyme-essential-oil
#8
Carla María Blanco-Lizarazo, Rubén Betancourt-Cortés, Angélica Lombana, Katerine Carrillo-Castro, Indira Sotelo-Díaz
The effects of the addition of nitrite at 200 ppm (N), sodium lactate 1.5% (L) and thyme essential oil at 100 ppm (T1) on Listeria monocytogenes behaviour and ATPase activity inhibition were evaluated, as well as lipid oxidation through the quantification of malonaldehydes, in sausage stored at 8 ℃ for 41 days and at 30 ℃ for 14 days. The changes in the colour profile were performed during storage time at 8 ℃. Quantitative descriptive sensory analyses were performed after two days at 4 ℃...
January 1, 2017: Food Science and Technology International, Ciencia y Tecnología de Los Alimentos Internacional
https://www.readbyqxmd.com/read/28067541/listeria-monocytogenes-circulating-in-rabbit-meat-products-and-slaughterhouses-in-italy-prevalence-data-and-comparison-among-typing-results
#9
Alessandra De Cesare, Antonio Parisi, Renzo Mioni, Damiano Comin, Alex Lucchi, Gerardo Manfreda
Rabbit meat has outstanding dietetic and nutritional properties. However, few data on microbiological hazards associated with rabbit productions are available. In this study, the presence of Listeria monocytogenes was determined in 430 rabbit carcasses, 256 rabbit meat cuts and products, and 599 environmental sponges collected from four Italian rabbit slaughterhouses over a period of 1 year. Prevalence of L. monocytogenes among the 1285 rabbit meat and environmental samples was 11%, with statistically significant differences between slaughterhouses...
January 9, 2017: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/28065808/bacterial-meningitis-in-alcoholic-patients-a-population-based-prospective-study
#10
Kiril E B van Veen, Matthijs C Brouwer, Arie van der Ende, Diederik van de Beek
OBJECTIVES: To study clinical features and outcome of community-acquired bacterial meningitis in alcoholic patients. METHODS: Patients with a history of alcoholism were selected from our nationwide, prospective cohort on community-acquired bacterial meningitis performed from March 2006 to October 2014. Data on patient history, symptoms and signs on admission, treatment, and outcome were prospectively collected. RESULTS: Of 1359 included episodes, 88 episodes (6%) occurred in 88 alcoholic patients...
January 5, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28065212/hospital-acquired-listeriosis-linked-to-a-persistently-contaminated-milkshake-machine
#11
E Mazengia, V Kawakami, K Rietberg, M Kay, P Wyman, C Skilton, A Aberra, J Boonyaratanakornkit, A P Limaye, S A Pergam, E Whimbey, R J Olsen-Scribner, J S Duchin
One case of hospital-acquired listeriosis was linked to milkshakes produced in a commercial-grade shake freezer machine. This machine was found to be contaminated with a strain of Listeria monocytogenes epidemiologically and molecularly linked to a contaminated pasteurized, dairy-based ice cream product at the same hospital a year earlier, despite repeated cleaning and sanitizing. Healthcare facilities should be aware of the potential for prolonged Listeria contamination of food service equipment. In addition, healthcare providers should consider counselling persons who have an increased risk for Listeria infections regarding foods that have caused Listeria infections...
January 9, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28065170/multistate-outbreak-of-listeria-monocytogenes-infections-linked-to-whole-apples-used-in-commercially-produced-prepackaged-caramel-apples-united-states-2014-2015
#12
K M Angelo, A R Conrad, A Saupe, H Dragoo, N West, A Sorenson, A Barnes, M Doyle, J Beal, K A Jackson, S Stroika, C Tarr, Z Kucerova, S Lance, L H Gould, M Wise, B R Jackson
Whole apples have not been previously implicated in outbreaks of foodborne bacterial illness. We investigated a nationwide listeriosis outbreak associated with caramel apples. We defined an outbreak-associated case as an infection with one or both of two outbreak strains of Listeria monocytogenes highly related by whole-genome multilocus sequence typing (wgMLST) from 1 October 2014 to 1 February 2015. Single-interviewer open-ended interviews identified the source. Outbreak-associated cases were compared with non-outbreak-associated cases and traceback and environmental investigations were performed...
January 9, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28062853/antibacterial-and-antivirulence-effect-of-6-n-hydroxylaminopurine-in-listeria-monocytogenes
#13
Stefanie Sandra Krajewski, Isabelle Isoz, Jörgen Johansson
The emerging development of antibiotic resistant bacteria calls for novel types of antibacterial agents. In this work we examined the putative antibacterial effect of purine analogs in Listeria monocytogenes We show that, among several tested purine analogs, only 6-N-hydroxylaminopurine (6-N-HAP) reduces the viability of the Gram-positive pathogen Listeria monocytogenes As in Bacillus subtilis, 6-N-HAP terminates expression at guanine riboswitches in L. monocytogenes hence preventing expression of their downstream genes...
January 6, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28059049/evaluation-of-the-3m%C3%A2-molecular-detection-assay-mda-2-listeria-monocytogenes-for-the-detection-of-listeria-monocytogenes-in-select-foods-and-environmental-surfaces-collaborative-study-first-action-2016-08
#14
Patrick Bird, Jonathan Flannery, Erin Crowley, James Agin, David Goins, Lisa Monteroso
The 3M<sup>™</sup> Molecular Detection Assay (MDA) 2 <em>- Listeria </em>uses loop-mediated isothermal amplification and bioluminescence detection to rapidly detect <em>Listeria </em>spp. in a broad range of food types and environmental surfaces. Using an unpaired study design, the MDA 2 - <em>Listeria </em>was compared to the U.S. Department of Agriculture Food Safety and Inspection Service <em>Microbiology Laboratory Guidebook </em>Chapter 8.09 "<em>Isolation and Identification of Listeria monocytogenes from Red Meat, Poultry, and Egg Products, and Environmental Samples</em>" reference method for the detection of <em>Listeria </em>in deli turkey and raw chicken breast fillet...
November 17, 2016: Journal of AOAC International
https://www.readbyqxmd.com/read/28058252/risk-assessment-in-the-recovery-of-food-for-social-solidarity-purposes-preliminary-data
#15
Vesna Milicevic, Giampaolo Colavita, Marta Castrica, Sabrina Ratti, Antonella Baldi, Claudia M Balzaretti
The most recent study, conducted by Politecnico of Milan, on food surplus management in Italy shows that in the Italian food supply chain the food surplus is around 5.5 million tons/year, and the amount of food wasted is around 5.1 million tons/year. During 2015, the charitable organizations (COs) belonging to the Italian Food Bank Network, active in recovering and distributing food for social solidarity's purposes, reused 381,345 tons of food from 2292 donors. The main supplying sources of the Banco Alimentare Network are: food industries, organized large-scale retail trade and collective catering service...
September 20, 2016: Italian Journal of Food Safety
https://www.readbyqxmd.com/read/28058251/evaluation-of-the-antibacterial-activity-of-bergamot-essential-oils-on-different-listeria-monocytogenes-strains
#16
Stefania M Marotta, Filippo Giarratana, Alessio Parco, Domenico Neri, Graziella Ziino, Alessandro Giuffrida, Antonio Panebianco
Essential oils are aromatic and volatile substances extracted from plants and characterized by antimicrobial activity. The aim of the present study was to evaluate the antibacterial activity (agar disc-diffusion method) of seven different bergamot essential oils (BEOs) on eight Listeria monocytogenes strains. Minimal inhibitory concentration (MIC) of most efficient BEOs was estimated. Extremely variable results for agar disc-diffusion method for L. monocytogenes strains were reported. One of the tested microorganisms resulted insensible to all the BEOs; 3 strains showed an inhibition from weak to null and the remaining 4 a variable susceptibility...
September 20, 2016: Italian Journal of Food Safety
https://www.readbyqxmd.com/read/28058249/microbiological-and-chemico-physical-shelf-life-and-panel-test-to-evaluate-acceptability-of-liver-mortadella
#17
Erica Tirloni, Simone Stella, Cristian Bernardi, Vittorio Maria Moretti, Carla Bersani, Patrizia Cattaneo
This study aimed to evaluate the shelf life of sliced cooked liver mortadella packaged in MAP (70-85% N2, 15-30% CO2) and stored in refrigeration (4°C) or slight thermal abuse (8°C) for up to 49 days (declared best before date 45 days). The proximate composition, aw nitrites and NaCl content were determined at T0. Weekly, samples were submitted to microbiological [total viable count (TVC), lactic acid bacteria (LAB), Enterobacteriaceae, Escherichia coli, Pseudomonas spp., coagulase positive staphylococci, sulphite reducing clostridia, yeasts and moulds, Listeria monocytogenes and Salmonella spp...
September 20, 2016: Italian Journal of Food Safety
https://www.readbyqxmd.com/read/28053218/singleton-st382-an-emerging-clonal-group-of-listeria-monocytogenes-associated-with-three-multistate-outbreaks-linked-to-contaminated-stone-fruit-caramel-apples-and-leafy-green-salad
#18
Yi Chen, Yan Luo, James Pettengill, Ruth Timme, David Melka, Matthew Doyle, Alikeh Jackson, Mickey Parish, Thomas S Hammack, Marc Allard, Eric W Brown, Errol A Strain
Three multistate outbreaks between 2014 and 2016, involving case patients in and outside the United States, were linked to stone fruit, caramel apples and packaged leafy green salad contaminated with Listeria monocytogenes singleton ST382. Isolates from these outbreaks and other ST382 isolates not associated with these outbreaks were analyzed by whole genome sequencing (WGS) analysis. The primary difference among these three ST382 outbreak strains were single nucleotide polymorphisms (SNPs). WGS analysis using these SNPs differentiated ST382 from a clonal complex 1 outbreak strain co-contaminating the caramel apples...
January 4, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28049493/presence-of-foodborne-pathogens-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-and-methicillin-resistant-staphylococcus-aureus-in-slaughtered-reindeer-in-northern-finland-and-norway
#19
Sauli Laaksonen, Antti Oksanen, Jérôme Julmi, Claudio Zweifel, Maria Fredriksson-Ahomaa, Roger Stephan
BACKGROUND: Various food-producing animals were recognized in recent years as healthy carriers of bacterial pathogens causing human illness. In northern Fennoscandia, the husbandry of semi-domesticated reindeer (Rangifer tarandus tarandus) is a traditional livelihood and meat is the main product. This study determined the presence of selected foodborne pathogens, methicillin-resistant Staphylococcus aureus (MRSA), and extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae in healthy semi-domesticated reindeer at slaughter in northern Finland and Norway...
January 3, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/28045978/cord-blood-acute-phase-reactants-predict-early-onset-neonatal-sepsis-in-preterm-infants
#20
Leena B Mithal, Hannah L Palac, Ram Yogev, Linda M Ernst, Karen K Mestan
BACKGROUND: Early onset sepsis (EOS) is a major cause of morbidity and mortality in preterm infants, yet diagnosis remains inadequate resulting in missed cases or prolonged empiric antibiotics with adverse consequences. Evaluation of acute phase reactant (APR) biomarkers in umbilical cord blood at birth may improve EOS detection in preterm infants with intrauterine infection. METHODS: In this nested case-control study, infants (29.7 weeks gestation, IQR: 27.7-32...
2017: PloS One
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