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https://www.readbyqxmd.com/read/29904971/a-subset-of-walnut-allergic-adults-is-sensitized-to-walnut-11s-globulin-jug-r-4
#1
Mark A Blankestijn, Constance F den Hartog Jager, W Marty Blom, Henny G Otten, G Aard H de Jong, Marco Gaspari, Geert F Houben, André C Knulst, Kitty C M Verhoeckx
BACKGROUND: The role of sensitization to commercially available allergens of English walnut (Juglans regia) Jug r 1, 2 and 3 in walnut allergy has been previously investigated in walnut allergic adults and was unable to explain allcases of walnut allergy. OBJECTIVES: Identify recognized walnut allergens, other than the ones previously investigated (Jug r 1-3), in walnut allergic adults and determine the sensitization frequency and diagnostic value. METHODS: Three different in-house walnut extracts were prepared and analysed on SDS-PAGE blots to identify allergenic walnut proteins...
June 15, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29792315/genomic-variation-among-and-within-six-juglans-species
#2
Kristian A Stevens, Keith Woeste, Sandeep Chakraborty, Marc W Crepeau, Charles A Leslie, Pedro J Martínez-García, Daniela Puiu, Jeanne Romero-Severson, Mark Coggeshall, Abhaya M Dandekar, Daniel Kluepfel, David B Neale, Steven L Salzberg, Charles H Langley
Genomic analysis in Juglans (walnuts) is expected to transform the breeding and agricultural production of both nuts and lumber. To that end, we report here the determination of reference sequences for six additional relatives of Juglans regia : Juglans sigillata (also from section Dioscaryon ), Juglans nigra , Juglans microcarpa, Juglans hindsii (from section Rhysocaryon ) , Juglans cathayensis (from section Cardiocaryon ), and the closely related Pterocarya stenoptera. While these are 'draft' genomes, ranging in size between 640Mbp and 990Mbp, their contiguities and accuracies can support powerful annotations of genomic variation that are often the foundation of new avenues of research and breeding...
May 23, 2018: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29772800/identification-and-expression-of-mirnas-related-to-female-flower-induction-in-walnut-juglans-regia-l
#3
Li Zhou, Shaowen Quan, Hang Xu, Li Ma, Jianxin Niu
Flower induction is an essential stage in walnut ( Juglans regia L.) trees, directly affecting yield, yield stability, fruit quality and commodity value. The objective of this study was to identify miRNAs related to female flower induction via high-throughput sequencing and bioinformatics analysis. A total of 123 miRNAs were identified including 51 known miRNAs and 72 novel miRNAs. Differential expression was observed in 19 of the known miRNAs and 34 of the novel miRNAs. Twelve miRNAs were confirmed by RT-qPCR...
May 17, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29770939/biomonitoring-levels-of-airborne-metals-around-urmia-lake-using-deciduous-trees-and-evaluation-of-their-tolerance-for-greenbelt-development
#4
Amir Mohammadi, Mehdi Mokhtari, Asghar Mosleh Arani, Hassan Taghipour, Yaghoub Hajizadeh, Hossein Fallahzadeh
In the northwest of Iran, the dust of salty and toxic metals possibly caused due to drying Urmia Lake is threatening the health of surrounding communities. This study aimed to employ leaves of local deciduous trees for biomonitoring of toxic elements and to evaluate air pollution tolerance of the trees for greenbelt application. Sampling from leaves of four dominant tree species including Vitis vinifera, Juglans regia, Ulmus umbraculifera, and Popolus alba was carried out from gardens in two radial distances (5 and 10 km) around the Urmia Lake accounting for 16 sites...
May 16, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29762631/aqueous-extracts-of-walnut-juglans-regia-l-leaves-quantitative-analyses-of-hydroxycinnamic-and-chlorogenic-acids
#5
Anggy Lusanna Gutiérrez Ortiz, Federico Berti, Luciano Navarini, Paola Crisafulli, Silvia Colomban, Cristina Forzato
Identification of both hydroxycinnamic and chlorogenic acids present in aqueous extracts of walnut leaves (Juglans regia L.) were carried out by using, for the first time, standard compounds not commercially available for qualitative identification. In particular, in addition to caffeic, ferulic, p-coumaric and sinapic acids, cis and trans mono-caffeoylquinic, dicaffeoylquinic, mono-feruloylquinic and cis and trans mono-p-coumaroylquinic acid isomers were detected and quantified by Ultra High Pressure Liquid Chromatography and the seasonal variations of these secondary metabolites were investigated...
May 14, 2018: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/29744610/walnut-phenolic-extract-inhibits-nuclear-factor-kappab-signaling-in-intestinal-epithelial-cells-and-ameliorates-experimental-colitis-and-colitis-associated-colon-cancer-in-mice
#6
Seong-Joon Koh, Youn-I Choi, Yuri Kim, Yoo-Sun Kim, Sang Woon Choi, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee
PURPOSE: Walnuts (Juglans regia) are known to have anti-cancer and immunomodulatory effects. However, little information is available on the effects of walnut phenolic extract (WPE) on intestinal inflammation and colitis-associated colon cancer. METHODS: COLO205 cells were pretreated with WPE and then stimulated with tumor necrosis factor (TNF)-α. In the acute colitis model, wild type mice (C57BL/6) were administered 4% dextran sulfate sodium (DSS) for 5 days. In the chronic colitis model, interleukin (IL)-10-/- mice were administered with either the vehicle or WPE (20 mg/kg) by oral gavage daily for 2 weeks...
May 9, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29735072/characterization-of-virgin-walnut-oils-and-their-residual-cakes-produced-from-different-varieties
#7
Rosa M Ojeda-Amador, María Desamparados Salvador, Sergio Gómez-Alonso, Giuseppe Fregapane
This study addresses the composition and properties of different walnut varieties (Chandler, Hartley and Lara), in particular their virgin oils and residual cakes obtained by screw pressing employing different cultivars. Among nuts, walnut (Juglans regia L.) exhibits interesting nutritional value, mainly due to their high content in linoleic acid, phenolic and tocopherol compounds, which show antioxidant and other healthy properties. Valuable results related to fatty acid profile and minor components were observed...
June 2018: Food Research International
https://www.readbyqxmd.com/read/29680922/bioindicator-responses-and-performance-of-plant-species-along-a-vehicular-pollution-gradient-in-western-himalaya
#8
Rachit Kashyap, Rohit Sharma, Sanjay Kr Uniyal
Loss of green cover, and increasing pollution is a prime global concern. The problem calls for screening of pollution-tolerant tree species that can be integrated into plantation drives. Recognizing this, the study analyzed bio-indicator responses and performance of commonly occurring plant species along a pollution gradient in western Himalaya. Based on distance from the road, three sites viz., highly polluted (HP), moderately polluted (MP), and least polluted (LP), were identified. From these sites, leaves of commonly occurring 26 tree species were collected and analyzed for dust accumulation, total chlorophyll, relative water content (RWC), ascorbic acid, and pH using standard protocols...
April 21, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29679714/population-genetics-phylogenomics-and-hybrid-speciation-of-juglans-in-china-determined-from-whole-chloroplast-genomes-transcriptomes-and-genotyping-by-sequencing-gbs
#9
Peng Zhao, Hui-Juan Zhou, Daniel Potter, Yi-Heng Hu, Xiao-Jia Feng, Meng Dang, Li Feng, Saman Zulfiqar, Wen-Zhe Liu, Gui-Fang Zhao, Keith Woeste
Genomic data are a powerful tool for elucidating the processes involved in the evolution and divergence of species. The speciation and phylogenetic relationships among Chinese Juglans remain unclear. Here, we used results from phylogenomic and population genetic analyses, transcriptomics, Genotyping-By-Sequencing (GBS), and whole chloroplast genomes (Cp genome) data to infer processes of lineage formation among the five native Chinese species of the walnut genus (Juglans, Juglandaceae), a widespread, economically important group...
April 18, 2018: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/29663801/identification-and-characterization-of-phenolic-compounds-in-black-walnut-kernels
#10
COMPARATIVE STUDY
Danh C Vu, Phuc H Vo, Mark V Coggeshall, Chung-Ho Lin
Black walnuts ( Juglans nigra L.) are highly valued for producing phenolic-enriched nuts. The objectives of this study were to identify and characterize the phenolic contents of 11 different black walnut cultivars and compare the levels of these phenolics between black walnuts and English walnut ( Juglans regia L.). Totally, 16 phenolics including phenolic acids, flavonoids, and catechins were identified in the black walnut kernels, with ellagic acid predominating over the other phenolics. Significant differences were noted for the levels of quinic acid, gallic acid, 1,3,6-trigalloylglucose, catechin, and penta- O-galloyl-β-d-glucose between the studied black walnuts and English walnut...
May 2, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29655676/protective-effect-of-juglans-regia-l-against-ultraviolet-b-radiation-induced-inflammatory-responses-in-human-epidermal-keratinocytes
#11
Umar Muzaffer, V I Paul, Nagarajan Rajendra Prasad, Ramasamy Karthikeyan, Balupillai Agilan
BACKGROUND: Juglans regia L. has a history of traditional medicinal use for the treatment of various maladies and have been documented with significant antioxidant and antiinflammatory properties. Although all parts of the plant are medicinally important, but male the flower of the plant has not been yet investigated against the photo-damage. PURPOSE: The present study, we sought to determine the photoprotective effect of the male flower of J. regia L. against ultraviolet-B radiation-induced inflammatory responses in human skin cells...
March 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29649523/prediction-of-the-antimicrobial-activity-of-walnut-juglans-regia-l-kernel-aqueous-extracts-using-artificial-neural-network-and-multiple-linear-regression
#12
Hatice Kavuncuoglu, Erhan Kavuncuoglu, Seyda Merve Karatas, Büsra Benli, Osman Sagdic, Hasan Yalcin
The mathematical model was established to determine the diameter of inhibition zone of the walnut extract on the twelve bacterial species. Type of extraction, concentration, and pathogens were taken as input variables. Two models were used with the aim of designing this system. One of them was developed with artificial neural networks (ANN), and the other was formed with multiple linear regression (MLR). Four common training algorithms were used. Levenberg-Marquardt (LM), Bayesian regulation (BR), scaled conjugate gradient (SCG) and resilient back propagation (RP) were investigated, and the algorithms were compared...
May 2018: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/29605650/evaluating-the-anti-biofilm-and-antibacterial-effects-of-juglans-regia-l-extracts-against-clinical-isolates-of-pseudomonas-aeruginosa
#13
Samaneh Dolatabadi, Hediyeh Nesari Moghadam, Maasoumeh Mahdavi-Ourtakand
OBJECTIVE: Pseudomonas aeruginosa, an opportunistic pathogen, can cause serious health problems and produces several virulence factors. The most important of these factors is biofilm. Many studies suggest administration of new generation of antibiotics, as P. aeruginosa biofilm has developed high resistance to antimicrobial drugs. Emergence of multidrug resistant (MDR) strains has resulted in screening biofilm inhibitors from natural products or modified from natural compounds. To test this hypothesis, we evaluated the inhibitory effects (antibacterial and antibiofilm) of Juglans regia L...
March 29, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29556565/-juglans-regia-l-protects-against-uvb-induced-apoptosis-in-human-epidermal-keratinocytes
#14
Umar Muzaffer, V I Paul, Nagarajan Rajendra Prasad, Ramasamy Karthikeyan
The present study was aimed to investigate the photoprotective effect of the male flower of J. regia L. (MEJR) against ultraviolet-B induced apoptosis in human skin cells. Human skin epidermal keratinocytes were pretreated with the MEJR (80 µg/ml, has been selected after MTT assay), prior to 30 min UVB-irradiation at a dose of 20 mJ/cm2 . Mitochondrial membrane potential was evaluated using Rhodamine-123 staining; the % apoptosis by Hoechst staining and acridine orange staining; DNA damage was measured by comet assay...
March 2018: Biochemistry and Biophysics Reports
https://www.readbyqxmd.com/read/29472324/complete-genome-sequence-of-xanthomonas-arboricola-pv-juglandis-strain-dw3f3-isolated-from-a-juglans-regia-l-bacterial-blighted-fruitlet
#15
Benzhong Fu, Qianqian Chen, Mi Wei, Jieqian Zhu, Lulu Zou, Guoyuan Li, Lihua Wang
Here, we report the complete genome sequence of Xanthomonas arboricola pv. juglandis DW3F3, a strong pathogenic strain isolated from blighted walnut immature fruit ( Juglans regia L. cv. Qingxiang). The genome consists of a single chromosome (5,144 kb).
February 22, 2018: Genome Announcements
https://www.readbyqxmd.com/read/29391625/bioefficacy-potential-of-different-genotypes-of-walnut-juglans-regia-l
#16
Uzma Noor Shah, Javid Iqbal Mir, Nazeer Ahmed, Sumira Jan, Khalid Majid Fazili
The purpose of investigation was to assess the phytochemical and nutraceutical of walnut in leaf extracts through diverse quantitative and qualitative phytochemical tests followed by array of assays. The screening of 50 elite walnut genotypes which exhibited wide range of discrepancy in terms of phytochemicals as well as their anti-oxidant potential was done. Walnut genotypes displayed maximum divergence in quercetin content (2.86-5.78 mg/100 g) as represented by cluster analysis. The phenolic rich genotypes exhibiting total phenols (37...
February 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29357825/the-walnut-jrvhag1-gene-is-involved-in-cadmium-stress-response-through-aba-signal-pathway-and-myb-transcription-regulation
#17
Zhenggang Xu, Yu Ge, Wan Zhang, Yunlin Zhao, Guiyan Yang
BACKGROUND: Vacuolar H+ -ATPase (V-ATPase) is a vital protein complex involved in abiotic stress response in plants. The G subunit of Juglans regia (JrVHAG1) was previously identified as a drought tolerance-related gene involved in the ABA (abscisic acid)-signal pathway. Heavy metal stress is becoming a major detriment for plant growth, development, and production. In order to understand the role of JrVHAG1, the potential function mechanism of JrVHAG1 exposed to CdCl2 stress was confirmed in this study...
January 22, 2018: BMC Plant Biology
https://www.readbyqxmd.com/read/29332575/protective-role-of-italian-juglans-regia-l-nut-ethanolic-extract-in-human-keratinocytes-under-oxidative-and-inflammatory-stress
#18
Cinzia Calcabrini, Umberto Mancini, Roberta De Bellis, Alessandra Frati, Anna Rita Mastrogiacomo, Giosue Annibalini, Piero Sestili, Luigi Cucchiarini, Vilberto Stocchi, Lucia Potenza
OBJECTIVE: In this research, fatty acid profile and polyphenolic content of an ethanolic extract of walnut from Juglans regia L. collected in Central Italy, were characterized. The potential antioxidant and anti-inflammatory effects of the extract were investigated in the human keratinocytes cell line. METHODS: Fatty acid profile was determined by gas chromatography/mass spectrometry analysis, total phenolic content by Folin-Ciocalteu method and aluminum chloride colorimetric method was used for determination of total flavonoids...
2017: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/29299206/therapeutic-potential-of-juglans-regia-l-leaf-extract-against-diabetic-retinopathy-in-rat
#19
Davood Nasiry, Ali Reza Khalatbary, Hassan Ahmadvand
Objectives: Oxidative stress has a pivotal role in the pathogenesis of diabetic retinopathy (DR). Juglans regia L . (JRL) leaf extract has hypoglycemic and antioxidative properties. This study aimed to determine the ameliorative effects of JRL against diabetic retinopathy. Materials and Methods: The DR rat model was generated by injection of streptozotocin (STZ). A subset of the diabetic rats received JRL or metformin after the onset of hyperglycemia. Histopathology and immunohistochemistry of apoptotic and inflammatory factors were assessed along with biochemical assessments of lipid peroxidation and antioxidant status...
November 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29286331/chemical-constituents-of-the-ethyl-acetate-extract-from-diaphragma-juglandis-fructus-and-their-inhibitory-activity-on-nitric-oxide-production-in-vitro
#20
Dan Wang, Yan Mu, Hongjing Dong, Huijiao Yan, Cui Hao, Xiao Wang, Lisi Zhang
Diaphragma juglandis fructus contains various bioactive constituents. Fourteen compounds were isolated from Diaphragma juglandis fructus by preparative high performance liquid chromatography (pre-HPLC) and high-speed counter-current chromatography (HSCCC). Their structures were identified by nuclear magnetic resonance (NMR) and electrospray ionization mass spectrometry (ESI-MS). Compounds (+)-dehydrovomifoliol ( 12 ), (6 R ,9 R )-9-hydroxymegastigman-4-en-3-one ( 13 ) and (6 R ,9 S )-9-hydroxymegastigman-4-en-3-one ( 14 ) are found from Juglans regia L...
December 29, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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