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MRI 7 Tesla

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https://www.readbyqxmd.com/read/29785155/the-volume-of-the-cerebellum-in-the-second-semester-of-gestation
#1
Damiana Vulturar, Alexandru Fărcăşanu, Flaviu Turcu, Dan Boitor, Carmen Crivii
Background and aims: The cerebellum ("little brain"), the largest part of hind brain, lies in the posterior cranial fossa, beneath the occipital lobe and dorsal to the brainstem. It develops over a long period: it is one of the first structures in the brain to begin to differentiate, but one of the last to mature. The use of ultrasonography has significantly improved the evaluation of fetal growth and development and has permitted prenatal diagnosis of a variety of congenital malformations...
2018: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29777819/7-tesla-magnetic-resonance-imaging-of-caudal-anterior-cingulate-and-posterior-cingulate-cortex-atrophy-in-patients-with-trigeminal-neuralgia
#2
Hyeong Cheol Moon, Chan-A Park, Yeong-Jae Jeon, Soon Tae You, Hyun Man Baek, Youn Joo Lee, Chul Beom Cho, Chae Joon Cheong, Young Seok Park
The cingulate cortex (CC) is a brain region that plays a key role in pain processing, but CC abnormalities are not unclear in patients with trigeminal neuralgia (TN). The purpose of this study was to determine the central causal mechanisms of TN and the surrounding brain structure in healthy controls and patients with TN using 7 Tesla (T) magnetic resonance imaging (MRI). Whole-brain parcellation in gray matter volume and thickness was assessed in 15 patients with TN and 16 healthy controls matched for sex, age, and regional variability using T1-weighted imaging...
May 16, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29776867/a-semi-automated-algorithm-for-hypothalamus-volumetry-in-3-tesla-magnetic-resonance-images
#3
Julia Wolff, Stephanie Schindler, Christian Lucas, Anne-Sophie Binninger, Luise Weinrich, Jan Schreiber, Ulrich Hegerl, Harald E Möller, Marco Leitzke, Stefan Geyer, Peter Schönknecht
The hypothalamus, a small diencephalic gray matter structure, is part of the limbic system. Volumetric changes of this structure occur in psychiatric diseases, therefore there is increasing interest in precise volumetry. Based on our detailed volumetry algorithm for 7 Tesla magnetic resonance imaging (MRI), we developed a method for 3 Tesla MRI, adopting anatomical landmarks and work in triplanar view. We overlaid T1-weighted MR images with gray matter-tissue probability maps to combine anatomical information with tissue class segmentation...
May 1, 2018: Psychiatry research. Neuroimaging
https://www.readbyqxmd.com/read/29750275/endoscopic-endonasal-transclival-approach-to-the-ventral-brainstem-anatomic-study-of-the-safe-entry-zones-combining-fiber-dissection-technique-with-7-tesla-magnetic-resonance-guided-neuronavigation
#4
Alessandro Weiss, Paolo Perrini, Matteo De Notaris, Guadalupe Soria, Alarcon Carlos, Maura Castagna, Lodovico Lutzemberger, Orazio Santo Santonocito, Giuseppe Catapano, Amin Kassam, Alberto Prats Galino
BACKGROUND: Treatment of intrinsic lesions of the ventral brainstem is a surgical challenge that requires complex skull base antero- and posterolateral approaches. More recently, endoscopic endonasal transclival approach (EETA) has been reported in the treatment of selected ventral brainstem lesions. OBJECTIVE: In this study we explored the endoscopic ventral brainstem anatomy with the aim to describe the degree of exposure of the ventral safe entry zones. In addition, we used a newly developed method combining traditional white matter dissection with high-resolution 7T magnetic resonance imaging (MRI) of the same specimen coregistered using a neuronavigation system...
May 10, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29746715/quantitative-susceptibility-map-analysis-in-preterm-neonates-with-germinal-matrix-intraventricular-hemorrhage
#5
Domenico Tortora, Mariasavina Severino, Jan Sedlacik, Benedetta Toselli, Mariya Malova, Alessandro Parodi, Giovanni Morana, Marco Massimo Fato, Luca Antonio Ramenghi, Andrea Rossi
BACKGROUND: Germinal matrix-intraventricular hemorrhage (GMH-IVH) is a common form of intracranial hemorrhage occurring in preterm neonates that may affect normal brain development. Although the primary lesion is easily identified on MRI by the presence of blood products, its exact extent may not be recognizable with conventional sequences. Quantitative susceptibility mapping (QSM) quantify the spatial distribution of magnetic susceptibility within biological tissues, including blood degradation products...
May 10, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29733378/assessing-the-predictability-of-idh-mutation-and-mgmt-methylation-status-in-glioma-patients-using-relaxation-compensated-multi-pool-cest-mri-at-7-0-tesla
#6
Daniel Paech, Johannes Windschuh, Johanna Oberhollenzer, Constantin Dreher, Felix Sahm, Jan-Eric Meissner, Steffen Goerke, Patrick Schuenke, Moritz Zaiss, Sebastian Regnery, Sebastian Bickelhaupt, Philipp Bäumer, Martin Bendszus, Wolfgang Wick, Andreas Unterberg, Peter Bachert, Mark Edward Ladd, Heinz-Peter Schlemmer, Alexander Radbruch
Background: Early identification of prognostic superior characteristics in glioma patients such as Isocitrate dehydrogenase(IDH)-mutation and O6-methylguanine-DNA-methyltransferase (MGMT) promotor methylation status is of great clinical importance. The study purpose was to investigate the non-invasive predictability of IDH-mutation status, MGMT promotor methylation, and differentiation of lower versus higher grade glioma (LGG vs. HGG) in newly-diagnosed patients employing relaxation-compensated multi-pool Chemical Exchange Saturation Transfer (CEST) magnetic resonance imaging (MRI) at 7...
May 4, 2018: Neuro-oncology
https://www.readbyqxmd.com/read/29723635/subchondral-bone-circulation-in-osteoarthritis-of-the-human-knee
#7
Roy K Aaron, Jennifer R Racine, Anne Voisinet, Peter Evangelista, Jonathan P Dyke
OBJECTIVE: The hypothesis of this study is that human subchondral bone exhibits abnormal patterns of perfusion in osteoarthritis (OA) that can be characterized by kinetic parameters of blood flow using dynamic contrast enhanced (DCE) MRI. DESIGN: Fifteen subjects with advanced OA of the knee and 7 control subjects without OA were studied at 1.5 Tesla with DCE-MRI. Region of interest (ROIs) analysis of pharmacokinetic perfusion parameters were used to examine initial uptake and washout of the contrast agent in the lateral tibial plateau...
April 30, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29719859/characterization-of-diffuse-orbital-mass-using-apparent-diffusion-coefficient-in-3-tesla-mri
#8
Sahar M ElKhamary, Alicia Galindo-Ferreiro, Laila AlGhafri, Rajiv Khandekar, Silvana Artioli Schellini
Purpose: To evaluate if the apparent diffusion coefficient (ADC) value in diffusion-weighted magnetic resonance imaging (DW-MRI) improves the diagnostic accuracy of diffuse orbital masses. Materials and methods: ADC DW-MRI was used to evaluate cases of diffuse orbital masses at our institution from 2000 to 2015. Lesions were grouped according to histopathologic diagnosis as, benign, pre-malignant and malignant. Lymphoproliferative lesions were further subgrouped as lymphoma or other lymphoproliferative lesions...
2018: European Journal of Radiology Open
https://www.readbyqxmd.com/read/29695597/involvement-of-the-central-somatosensory-system-in-restless-legs-syndrome-a-neuroimaging-study
#9
Byeong-Yeul Lee, Jongmyeong Kim, James R Connor, Gerald D Podskalny, Yeunchul Ryu, Qing X Yang
OBJECTIVE: To investigate morphologic changes in the somatosensory cortex and the thickness of the corpus callosum subdivisions that provide interhemispheric connections between the 2 somatosensory cortical areas. METHODS: Twenty-eight patients with severe restless legs syndrome (RLS) symptoms and 51 age-matched healthy controls were examined with high-resolution MRI at 3.0 tesla. The vertex-wise analysis in conjunction with a novel cortical surface classification method was performed to assess the cortical thickness across the whole-brain structures...
April 25, 2018: Neurology
https://www.readbyqxmd.com/read/29689381/on-the-use-of-superparamagnetic-hydroxyapatite-nanoparticles-as-an-agent-for-magnetic-and-nuclear-in-vivo-imaging
#10
Alessio Adamiano, Michele Iafisco, Monica Sandri, Martina Basini, Paolo Arosio, Tamara Canu, Giovanni Sitia, Antonio Esposito, Vincenzo Iannotti, Giovanni Ausanio, Eirini Fragogeorgi, Maritina Rouchota, George Loudos, Alessandro Lascialfari, Anna Tampieri
The identification of alternative biocompatible magnetic NPs for advanced clinical application is becoming an important need due to raising concerns about iron accumulation in soft issues associated to the administration of superparamagnetic iron oxide nanoparticles (NPs). Here, we report on the performance of previously synthetized iron-doped hydroxyapatite (FeHA) NPs as contrast agent for magnetic resonance imaging (MRI). The MRI contrast abilities of FeHA and Endorem® (dextran coated iron oxide NPs) were assessed by 1 H nuclear magnetic resonance relaxometry and their performance in healthy mice was monitored by a 7 Tesla scanner...
April 21, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29687149/shoulder-muscle-volume-and-fat-content-in-healthy-adult-volunteers-quantification-with-dixon-mri-to-determine-the-influence-of-demographics-and-handedness
#11
Pascal S Kälin, Rebecca J Crawford, Magda Marcon, Andrei Manoliu, Samy Bouaicha, Michael A Fischer, Erika J Ulbrich
OBJECTIVE: We aimed to provide mean values for fat-fraction and volume for full-length bilateral rotator cuff and deltoid muscles in asymptomatic adults selected on the basis of their good musculoskeletal and systemic health, and to understand the influence of gender, age, and arm dominance. MATERIALS AND METHODS: Seventy-six volunteers aged 20 to 60 years who were screened for normal BMI and high general health were included in the study. MRI was performed at 3 Tesla using three-point DIXON sequences...
April 23, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29665290/timely-visualization-of-the-collaterals-formed-during-acute-ischemic-stroke-with-fe-3-o-4-nanoparticle-based-mr-imaging-probe
#12
Ting Wang, Yi Hou, Bo Bu, Wenxin Wang, Tiancong Ma, Chunyan Liu, Lan Lin, Lin Ma, Xin Lou, Mingyuan Gao
Ischemic stroke is one of the major leading causes for long-term disability and mortality. Collateral vessels provide an alternative pathway to protect the brain against ischemic injury after arterial occlusion. Aiming at visualizing the collaterals occurring during acute ischemic stroke, an integrin αv β3 -specific Fe3 O4 -Arg-Gly-Asp (RGD) nanoprobe is prepared for magnetic resonance imaging (MRI) of the collaterals. Rat models are constructed by occluding the middle cerebral artery for imaging studies of cerebral ischemia and ischemia-reperfusion on 7...
April 17, 2018: Small
https://www.readbyqxmd.com/read/29663419/accelerated-3d-bssfp-imaging-for-treatment-planning-on-an-mri-guided-radiotherapy-system
#13
Yu Gao, Ziwu Zhou, Fei Han, Minsong Cao, Narek Shaverdian, John V Hegde, Biraj B Bista, Michael Steinberg, Percy Lee, Ann Raldow, Daniel A Low, Yingli Yang, Peng Hu
PURPOSE: To introduce a compressed sensing and parallel imaging combined technique to reduce the acquisition time of planning MRI for MR-guided radiotherapy (MRgRT) systems. METHODS AND MATERIALS: A variable-density Poisson-Disk (VDPD) under-sampling acquisition along with compressed sensing reconstruction technique was developed and compared with the current planning MR protocol, which uses an optimized balanced-steady-state-free-precession sequence with 7.5-fold (7...
April 16, 2018: Medical Physics
https://www.readbyqxmd.com/read/29656389/the-robustness-of-t-2-value-as-a-trabecular-structural-index-at-multiple-spatial-resolutions-of-7-tesla-mri
#14
D K Lee, Y K Song, B W Park, H P Cho, J S Yeom, G Cho, H Cho
PURPOSE: To evaluate the robustness of MR transverse relaxation times of trabecular bone from spin-echo and gradient-echo acquisitions at multiple spatial resolutions of 7 T. METHODS: The effects of MRI resolutions to T2 and T2* of trabecular bone were numerically evaluated by Monte Carlo simulations. T2 , T2*, and trabecular structural indices from multislice multi-echo and UTE acquisitions were measured in defatted human distal femoral condyles on a 7 T scanner...
April 15, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29652919/preparation-and-characterization-of-fe3o4-au-c225-composite-targeted-nanoparticles-for-mri-of-human-glioma
#15
Yaoqi Ge, Yuejiao Zhong, Guozhong Ji, Qianling Lu, Xinyu Dai, Zhirui Guo, Peng Zhang, Gang Peng, Kangzhen Zhang, Yuntao Li
OBJECTIVE: To study the characterization of Fe3O4@Au-C225 composite targeted MNPs. METHODS: Fe3O4@Au-C225 was prepared by the absorption method. The immunosorbent assay was used to evaluate its absorption efficiency at C225 Fc. ZETA SIZER3000 laser particle size analyzer, ultraviolet photometer and its characteristics were analyzed by VSM. the targeting effect of Fe3O4@Au-C225 composite targeted MNPs on U251 cells in vitro were detected by 7.0 Tesla Micro-MR; and subcutaneous transplanted human glioma in nude mice were performed the targeting effect in vivo after tail vein injection of Fe3O4@Au-C225 composite targeted MNPs by MRI...
2018: PloS One
https://www.readbyqxmd.com/read/29649085/tract-specific-volume-loss-on-3t-mri-in-patients-with-cervical-spondylotic-myelopathy
#16
Benjamin S Hopkins, Kenneth A Weber, Michael Brendan Cloney, Monica Paliwal, Todd B Parrish, Zachary A Smith
STUDY DESIGN: Case-control. OBJECTIVE: The aim of this study was to understand the role of high-resolution magnetic resonance (MR) in identifying regional cord volume loss in cervical spondylotic myelopathy (CSM). SUMMARY OF BACKGROUND DATA: Preliminary studies suggest that compression of the ventral region of the cord may contribute disproportionately to CSM symptomology; however, tract-specific data are lacking in the CSM population. The current study is the first to use 3T MR imaging (MRI) images of CSM patients to determine specific volume loss at the level of detail of individual descending white matter tracts...
April 11, 2018: Spine
https://www.readbyqxmd.com/read/29624567/clinical-value-of-dorsal-medulla-oblongata-involvement-detected-with-conventional-mri-for-prediction-of-outcome-in-children-with-enterovirus-71-related-brainstem-encephalitis
#17
Kun Liu, Yongjin Zhou, Shihan Cui, Jiawen Song, Peipei Ye, Wei Xiang, Xiaoyan Huang, Yiping Chen, Zhihan Yan, Xinjian Ye
BACKGROUND: Brainstem encephalitis is the most common neurologic complication after enterovirus 71 infection. The involvement of brainstem, especially the dorsal medulla oblongata, can cause severe sequelae or death in children with enterovirus 71 infection. We aimed to determine the prevalence of dorsal medulla oblongata involvement in children with enterovirus 71-related brainstem encephalitis (EBE) by using conventional MRI and to evaluate the value of dorsal medulla oblongata involvement in outcome prediction...
April 5, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29621724/development-of-hypertension-after-long-term-exposure-to-static-magnetic-fields-among-workers-from-a-magnetic-resonance-imaging-device-manufacturing-facility
#18
Suzan Bongers, Pauline Slottje, Hans Kromhout
OBJECTIVE: To assess the association between long-term exposure to static magnetic fields (SMF) in a magnetic resonance imaging (MRI)-manufacturing environment and hypertension. METHODS: In an occupational cohort of male workers (n = 538) of an MRI-manufacturing facility, the first and last available blood pressure measurements from the facility's medical surveillance scheme were associated with modeled cumulative exposure to SMF. Exposure modeling was based on linkage of individual job histories from the facility's personnel records with a facility specific historical job exposure matrix...
April 2, 2018: Environmental Research
https://www.readbyqxmd.com/read/29603381/high-resolution-whole-brain-diffusion-mri-at-7t-using-radiofrequency-parallel-transmission
#19
Xiaoping Wu, Edward J Auerbach, An T Vu, Steen Moeller, Christophe Lenglet, Sebastian Schmitter, Pierre-François Van de Moortele, Essa Yacoub, Kâmil Uğurbil
PURPOSE: Investigating the utility of RF parallel transmission (pTx) for Human Connectome Project (HCP)-style whole-brain diffusion MRI (dMRI) data at 7 Tesla (7T). METHODS: Healthy subjects were scanned in pTx and single-transmit (1Tx) modes. Multiband (MB), single-spoke pTx pulses were designed to image sagittal slices. HCP-style dMRI data (i.e., 1.05-mm resolutions, MB2, b-values = 1000/2000 s/mm2 , 286 images and 40-min scan) and data with higher accelerations (MB3 and MB4) were acquired with pTx...
March 30, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29588945/seven-tesla-mri-improves-detection-of-focal-cortical-dysplasia-in-patients-with-refractory-focal-epilepsy
#20
Tim J Veersema, Cyrille H Ferrier, Pieter van Eijsden, Peter H Gosselaar, Eleonora Aronica, Fredy Visser, Jaco M Zwanenburg, Gerard A P de Kort, Jeroen Hendrikse, Peter R Luijten, Kees P J Braun
Objective: The aim of this study is to determine whether the use of 7 tesla (T) MRI in clinical practice leads to higher detection rates of focal cortical dysplasias in possible candidates for epilepsy surgery. Methods: In our center patients are referred for 7 T MRI if lesional focal epilepsy is suspected, but no abnormalities are detected at one or more previous, sufficient-quality lower-field MRI scans, acquired with a dedicated epilepsy protocol, or when concealed pathology is suspected in combination with MR-visible mesiotemporal sclerosis-dual pathology...
June 2017: Epilepsia Open
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