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https://www.readbyqxmd.com/read/28638994/adherence-to-mediterranean-diet-in-relation-to-bone-mineral-density-and-risk-of-fracture-a-systematic-review-and-meta-analysis-of-observational-studies
#1
Hanieh Malmir, Parvane Saneei, Bagher Larijani, Ahmad Esmaillzadeh
PURPOSE: We aimed to systematically review available data on the association between adherence to MD and BMD as well as risk of fractures and to summarize this information through a meta-analysis. METHODS: Previous studies in the field of adherence to MD in relation to BMD and risk of fracture were selected through searching PubMed, Scopus, ISI Web of Science and Google Scholar databases prior to June, 2016 using Mesh and non-Mesh relevant keywords. RESULTS: In the meta-analysis of four effect sizes, obtained from three studies, we found that adherence to MD was associated with a 21% reduced risk of hip fracture (overall RR 0...
June 21, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28627027/elevated-serum-myostatin-level-is-associated-with-worse-survival-in-patients-with-liver-cirrhosis
#2
Hiroki Nishikawa, Hirayuki Enomoto, Akio Ishii, Yoshinori Iwata, Yuho Miyamoto, Noriko Ishii, Yukihisa Yuri, Kunihiro Hasegawa, Chikage Nakano, Takashi Nishimura, Kazunori Yoh, Nobuhiro Aizawa, Yoshiyuki Sakai, Naoto Ikeda, Tomoyuki Takashima, Ryo Takata, Hiroko Iijima, Shuhei Nishiguchi
BACKGROUND: We aimed to elucidate the relationship between serum myostatin levels and other markers including skeletal muscle mass and to investigate the influence of serum myostatin levels on survival for patients with liver cirrhosis (LC). METHODS: A total of 198 LC subjects were analysed in this study. Myostatin levels were measured using stored sera. We retrospectively investigated the relationship between myostatin level and other markers, and the influence of myostatin level on overall survival (OS)...
June 18, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28582838/the-effect-of-gigantomasty-on-vertebral-degeneration-a-computed-tomography-study
#3
Bekir Sanal, Mehmet Korkmaz, Omer Fatih Nas, Fatma Can, Kadir Hacikurt
The main reason for waist and back pain in patients with gigantomasty is increased thoracic kyphosis and lumber lordosis. These symptoms and abnormal spinal angulations regress after reduction mammoplasty operations. However, the effect of chronic mechanical stress caused by gigantomasty on the spinal degenerative process is not clear yet. In this study with computed tomography it is shown that degenerative spondylosis is more widespread and severe in patients with large breasts.
May 12, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28565778/value-of-a-new-pathological-classification-of-lumbar-intervertebral-disc-herniation-based-on-transforaminal-endoscopic-observations
#4
Lin Yang, Hong-Hui Lu
Removal of herniated disc materials based on an imaging only method may not relieve symptoms in many patients. Therefore, the aim of the present study was to develop a transforaminal endoscopic method of classifying the pathological type of lumber intervertebral disc herniation and to compare the outcomes of surgery based on the pathological type with those of conventional endoscopic disc removal. The records of patients who received endoscopic transforaminal nucleotomy with foraminoplasty for symptomatic lumbar disc herniation between 2009 and 2013 were retrospectively reviewed...
May 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28561274/statistical-shape-modelling-of-hip-and-lumbar-spine-morphology-and-their-relationship-in-the-mrc-national-survey-of-health-and-development
#5
Anastasia V Pavlova, Fiona R Saunders, Stella G Muthuri, Jennifer S Gregory, Rebecca J Barr, Kathryn R Martin, Rebecca J Hardy, Rachel Cooper, Judith E Adams, Diana Kuh, Richard M Aspden
The anatomical shape of bones and joints is important for their proper function but quantifying this, and detecting pathological variations, is difficult to do. Numerical descriptions would also enable correlations between joint shapes to be explored. Statistical shape modelling (SSM) is a method of image analysis employing pattern recognition statistics to describe and quantify such shapes from images; it uses principal components analysis to generate modes of variation describing each image in terms of a set of numerical scores after removing global size variation...
May 31, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28560121/comparison-of-different-analgesia-drug-regimens-for-pain-control-during-extracorporeal-shock-wave-lithotripsy-for-renal-stones-a-randomized-control-study
#6
Muhammad Waqas, Amna Butt, Mohammad Ayaz Khan, Ijaz Khan, Imad-Ud-Din Saqib, Tariq Hussain, Saeed Akhter
INTRODUCTION: With the increased use of extracorporeal shock wave lithotripsy (ESWL), the management of urolithiasis has become much convenient for the patients and the health care professionals alike. However, associated with the procedure is the common complaint of pain. No agreed upon pain management strategy has yet been developed for the procedure. We compared the effect of different analgesia drug regiments for pain control. METHODOLOGY: A randomised controlled trial was carried out in Shifa International Hospital from between July 2015 to January 2016...
April 26, 2017: Curēus
https://www.readbyqxmd.com/read/28535642/-clinical-effects-of-dynesys-system-and-transfacet-decompression-through-wiltse-approach-in-the-treatment-of-lumbar-degenerative-diseases
#7
K Shang, M J Chen, D G Wang
Objective: To investigate the early clinical effects of Dynesys system and transfacet decompression by Wiltse approach in the treatment of lumbar degenerative diseases. Methods: From January 2010 to December 2013, 48 patients suffering from lumbar degenerative diseases were treated with Dynesys system in addition to transfacet decompression through Wiltse approach.There were 28 males and 20 females with age of (51.8±6.8). The preoperative diagnosis included lumbar spinal stenosis(10 cases); lumber intervertebral disc herniation (38 cases)...
May 23, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28517243/sarcopenia-is-a-risk-factor-for-falling-in-independently-living-japanese-older-adults-a-2-year-prospective-cohort-study-of-the-gaina-study
#8
Hiromi Matsumoto, Chika Tanimura, Shinji Tanishima, Mari Osaki, Hisashi Noma, Hiroshi Hagino
AIM: The purpose of the present study was to investigate whether sarcopenia was associated with future falls in the general Japanese older population. METHODS: This study was a 2-year prospective observational study. Participants were recruited from individuals who had an annual town-sponsored medical check-up and had not received nursing care. The inclusion criteria for participants in our study were: (i) agreement to participate; (ii) living independently; and (iii) the ability to walk to where the survey was carried out and to provide self-reported data...
May 18, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28511840/quantitative-assessment-of-trunk-deformation-during-running
#9
Shoma Kudo, Masahiro Fujimoto, Tadao Isaka, Akinori Nagano
The trunk has a multi-segmental structure and is composed of the cervical, thoracic, and lumber spines and surrounding soft tissue elements; this allows flexible deformation during dynamic movements. The purpose of this study was to quantitatively assess trunk deformation during dynamic movement. Ten male subjects performed running at four different speeds: 8km/h, 10km/h, 12km/h, and 14km/h. Forty reflective markers were placed on the backs of these individuals to define 56 small triangular areas, and three-dimensional kinematic data was recorded with a motion capture system...
May 5, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28489785/effect-of-psoas-muscle-mass-after-endoscopic-therapy-for-patients-with-esophageal-varices
#10
Hiroki Nishikawa, Yukihisa Yuri, Hirayuki Enomoto, Akio Ishii, Yoshinori Iwata, Yuho Miyamoto, Noriko Ishii, Kunihiro Hasegawa, Chikage Nakano, Takashi Nishimura, Kazunori Yoh, Nobuhiro Aizawa, Yoshiyuki Sakai, Naoto Ikeda, Tomoyuki Takashima, Ryo Takata, Hiroko Iijima, Shuhei Nishiguchi
We aimed to investigate the impact of decrease of muscle mass on survival after eradication of esophageal varices (EVs) treated by endoscopic therapies as a primary prophylaxis in patients with liver cirrhosis (LC). In all, 177 LC individuals with EVs undergoing endoscopic therapies were analyzed. We retrospectively examined the impact of muscle mass decrease as determined by psoas muscle mass (PMM) at the third lumber on computed tomography (depletion of PMM [DPMM]) on survival as compared with serum sodium combined Model for End-stage Liver Disease (MELD-Na)...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28486515/beyond-knowing-nature-contact-emotion-compassion-meaning-and-beauty-are-pathways-to-nature-connection
#11
Ryan Lumber, Miles Richardson, David Sheffield
Feeling connected to nature has been shown to be beneficial to wellbeing and pro-environmental behaviour. General nature contact and knowledge based activities are often used in an attempt to engage people with nature. However the specific routes to nature connectedness have not been examined systematically. Two online surveys (total n = 321) of engagement with, and value of, nature activities structured around the nine values of the Biophila Hypothesis were conducted. Contact, emotion, meaning, and compassion, with the latter mediated by engagement with natural beauty, were predictors of connection with nature, yet knowledge based activities were not...
2017: PloS One
https://www.readbyqxmd.com/read/28484677/iatrogenic-non-reconstructable-duodenal-injury-presenting-without-peritonitis-an-indication-of-pancreatoduodenectomy-in-the-presence-of-safe-hands-a-case-report
#12
Humaid Ahmad, Jahanzaib Haider, Sheeraz S Siddiqui, Sumbul Naz, Shams Nadeem Alam
Iatrogenic duodenal injuries are rare complications of upper gastrointestinal endoscopic procedures, gallbladder, and right kidney operations. Management includes diverse options depending on a number of factors that include the size of the injury, timing of presentation, degree of peritoneal contamination, and presence of peritonitis and/or sepsis, etc. While most duodenal injuries are small, large complex non-reconstructable injuries may occasionally occur, requiring complex surgical procedures rather than primary repair which if done in the latter cases, may lead to further morbidity and mortality...
April 6, 2017: Curēus
https://www.readbyqxmd.com/read/28448933/in-vitro-bioaccessibility-of-copper-azole-following-simulated-dermal-transfer-from-pressure-treated-wood
#13
Jennifer L Griggs, Kim R Rogers, Clay Nelson, Todd Luxton, William E Platten, Karen D Bradham
Micronized copper azole (MCA) and micronized copper quaternary (MCQ) are the latest wood preservatives to replace the liquid alkaline copper and chromated copper arsenate preservatives due to concerns over the toxicity or lack of effectiveness of the earlier formulations. Today, the use of MCA has become abundant in the wood preservative industry with approximately 38millionlbs of copper carbonate being used to treat lumber each year. Despite this widespread usage, little information is available on the bioaccessibility of this preservative upon gastrointestinal exposure...
November 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28386930/post-traumatic-stress-disorder-symptoms-in-pregnant-australian-indigenous-women-residing-in-rural-and-remote-new-south-wales-a-cross-sectional-descriptive-study
#14
Beth Mah, Loretta Weatherall, Julie Burrows, Caroline C Blackwell, Josephine Gwynn, Pathik Wadhwa, Eugenie R Lumbers, Roger Smith, Kym M Rae
BACKGROUND: Pregnancy can be a stressful time for many women. There is ample evidence of numerous physical and mental health inequities for Indigenous Australians. For those Indigenous women who are pregnant, it is established that there is a higher incidence of poor physical perinatal outcomes when compared with non-Indigenous Australians. However, little evidence exists that examines stressful events and post-traumatic stress disorder (PTSD) symptoms in pregnant women who are members of this community...
April 7, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28356508/the-druggable-genome-and-support-for-target-identification-and-validation-in-drug-development
#15
Chris Finan, Anna Gaulton, Felix A Kruger, R Thomas Lumbers, Tina Shah, Jorgen Engmann, Luana Galver, Ryan Kelley, Anneli Karlsson, Rita Santos, John P Overington, Aroon D Hingorani, Juan P Casas
Target identification (determining the correct drug targets for a disease) and target validation (demonstrating an effect of target perturbation on disease biomarkers and disease end points) are important steps in drug development. Clinically relevant associations of variants in genes encoding drug targets model the effect of modifying the same targets pharmacologically. To delineate drug development (including repurposing) opportunities arising from this paradigm, we connected complex disease- and biomarker-associated loci from genome-wide association studies to an updated set of genes encoding druggable human proteins, to agents with bioactivity against these targets, and, where there were licensed drugs, to clinical indications...
March 29, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28327138/accuracy-of-pedicle-screw-placement-in-patients-with-marfan-syndrome
#16
Jun Qiao, Feng Zhu, Leilei Xu, Zhen Liu, Xu Sun, Bangping Qian, Qing Jiang, Zezhang Zhu, Yong Qiu
BACKGROUND: There is no study concerning safety and accuracy of pedicle screw placement in Marfan syndrome. The objective of this study is to investigate accuracy and safety of pedicle screw placement in scoliosis associated with Marfan syndrome. METHODS: CT scanning was performed to analyze accuracy of pedicle screw placement. Pedicle perforations were classified as medial, lateral or anterior and categorized to four grades: ≤ 2 mm as Grade 1, 2.1-4.0 mm as Grade 2, 4...
March 21, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28318555/regulation-of-the-prorenin-angiotensin-system-by-oxygen-and-mirnas-parallels-between-placentation-and-tumour-development
#17
Sarah J Delforce, Eugenie R Lumbers, Kirsty G Pringle
Tissue renin-angiotensin systems (RASs) are involved in tissue growth and development as they are important regulators of angiogenesis, cell proliferation and migration. The placental RAS is most highly expressed in early gestation, at a time when the oxygen tension within the conceptus is reduced, and plays a key role in placental growth and development. Similar to the placenta, tumour development relies on proliferation, angiogenesis and invasion in order to grow and metastasize. The RAS is known to be upregulated in a variety of solid tumours, including ovarian, endometrial, cervical, breast and prostate...
March 10, 2017: Placenta
https://www.readbyqxmd.com/read/28254286/synchrotron-based-xrd-from-rat-bone-of-different-age-groups
#18
D V Rao, G E Gigante, R Cesareo, A Brunetti, N Schiavon, T Akatsuka, T Yuasa, T Takeda
Synchrotron-based XRD spectra from rat bone of different age groups (w, 56 w and 78w), lumber vertebra at early stages of bone formation, Calcium hydroxyapatite (HAp) [Ca10(PO4)6(OH)2] bone fill with varying composition (60% and 70%) and bone cream (35-48%), has been acquired with 15keV synchrotron X-rays. Experiments were performed at Desy, Hamburg, Germany, utilizing the Resonant and Diffraction beamline (P9), with 15keV X-rays (λ=0.82666 A(0)). Diffraction data were quantitatively analyzed using the Rietveld refinement approach, which allowed us to characterize the structure of these samples in their early stages...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28224100/early-infant-male-circumcision-systematic-review-risk-benefit-analysis-and-progress-in-policy
#19
Brian J Morris, Sean E Kennedy, Alex D Wodak, Adrian Mindel, David Golovsky, Leslie Schrieber, Eugenie R Lumbers, David J Handelsman, John B Ziegler
AIM: To determine whether recent evidence-based United States policies on male circumcision (MC) apply to comparable Anglophone countries, Australia and New Zealand. METHODS: Articles in 2005 through 2015 were retrieved from PubMed using the keyword "circumcision" together with 36 relevant subtopics. A further PubMed search was performed for articles published in 2016. Searches of the EMBASE and Cochrane databases did not yield additional citable articles. Articles were assessed for quality and those rated 2+ and above according to the Scottish Intercollegiate Grading System were studied further...
February 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/28216610/pulmonary-kaposi-sarcoma-with-osseous-metastases-in-an-human-immunodeficiency-virus-hiv-patient-a-remarkable-response-to-highly-active-antiretroviral-therapy
#20
Ahmed Dirweesh, Muhammad Yasir Khan, Shaikh Fawad Hamiz, Nigahus Karabulut
BACKGROUND Kaposi sarcoma (KS) is known to involve the mucocutaneous tissues and the aero-digestive tracts. In acquired immune deficiency syndrome (AIDS) patients, KS has an aggressive course and carries poor prognosis. We present a case of pulmonary KS with osseous metastases as the first presentation of human immunodeficiency virus (HIV) infection in a young male. The lesions impressively decreased in size and numbers following initiation of highly active antiretroviral therapy (HAART). CASE REPORT A 34-year-old heterosexual male presented with a one month history of cough and 15-20 pound weight loss within six months...
February 20, 2017: American Journal of Case Reports
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