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https://www.readbyqxmd.com/read/29329586/il-33-st2-signaling-contributes-to-radicular-pain-by-modulating-mapk-and-nf-%C3%AE%C2%BAb-activation-and-inflammatory-mediator-expression-in-the-spinal-cord-in-rat-models-of-noncompressive-lumber-disk-herniation
#1
Si-Jian Huang, Jian-Qin Yan, Hui Luo, Lu-Yao Zhou, Jian-Gang Luo
BACKGROUND: Immune and inflammatory responses occurring in the spinal cord play a pivotal role in the progression of radicular pain caused by intervertebral disk herniation. Interleukin-33 (IL-33) orchestrates inflammatory responses in a wide range of inflammatory and autoimmune disorders of the nervous system. Thus, the purpose of this study is to investigate the expression of IL-33 and its receptor ST2 in the dorsal spinal cord and to elucidate whether the inhibition of spinal IL-33 expression significantly attenuates pain-related behaviors in rat models of noncompressive lumbar disc herniation...
January 12, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29324909/effect-of-hypoparathyroid-on-bone-mineral-density-of-lumber-spine-in-postmenopausal-women-with-differentiated-thyroid-cancinoma
#2
Yongli Bai, Yanlei Huo, Fei Yu, Danyang Wang, Chao Ma
OBJECTIVE: To investigate the effect of hypoparathyroid on bone mineral density in postmenopausal women with differentiated thyroid carcinoma (DTC). SUBJECT AND METHODS: Postmenopausal women with postoperative DTC, and undergoing thyroid residual ablation or for metastases treatment were collected and followed for two years. They were divided into hypoparathyroid group (PTH<15pg/mL) and a normal cognitive group (PTH>15pg/mL). Bone mineral density (BMD) at the lumbar spine was analyzed using dual-energy X-ray absorptiometry (DXA) at baseline, 6, 12 and 24 months...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29322706/osteoporosis-in-postmenopausal-females-with-primary-knee-osteoarthritis-in-a-vitamin-d-deficient-population
#3
Pooja Dhaon, Siddharth Kumar Das, Ragini Srivastava, Akash Asthana, Girdhar Agarwal
Aim and Objective: To find prevalence of osteoporosis (OP) in postmenopausal females with primary knee osteoarthritis (OA) in India, where there is widespread Vitamin D deficiency (VDD). Material and Methods: 75 postmenopausal women (PMW) fulfilling ACR criteria for Knee OA between 40 - 60 years of age, having OA grade 2 or more as per Kellgren Lawrence grade on anterior- posterior radiograph of the right knee were enrolled. 34 PMW of the same age with normal right knee radiograph were taken as controls...
November 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29317155/compensatory-mechanism-of-the-spine-after-corrective-surgery-without-lumbar-sacral-fixation-for-traumatic-thoracolumbar-kyphotic-spine-deformity
#4
Koji Matsumoto, Masahiro Hoshino, Keita Omori, Hidetoshi Igarashi, Takashi Tsuruta, Koji Yamasaki, Hiromi Matsuzaki, Takanori Iriuchishima, Yasuaki Tokuhashi
BACKGROUND: It remains unclear whether long fusion including lumbar-sacral fixation is needed in corrective surgery to obtain good global sagittal balance (GSB) for the treatment of traumatic thoracolumbar kyphotic spine deformity. The purposes of this study were to evaluate compensatory mechanism of the spine after corrective surgery without lumbar-sacral fixation and to evaluate the parameters affecting the achievement of good GSB post-operatively. METHODS: Twenty (20) subjects requiring corrective surgery (distal end of fixation was L3) were included in this study...
January 6, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29310350/relationship-between-skeletal-muscle-mass-and-liver-fibrosis-markers-for-patients-with-hepatitis-c-virus-related-liver-disease
#5
Ryo Takata, Hiroki Nishikawa, Hirayuki Enomoto, Yoshinori Iwata, Akio Ishii, Yuho Miyamoto, Noriko Ishii, Yukihisa Yuri, Kunihiro Hasegawa, Chikage Nakano, Takashi Nishimura, Kazunori Yoh, Nobuhiro Aizawa, Yoshiyuki Sakai, Naoto Ikeda, Tomoyuki Takashima, Hiroko Iijima, Shuhei Nishiguchi
We aimed to elucidate the relationship between serum liver fibrosis markers (Mac-2 binding protein glycosylation isomer (M2BPGi), FIB-4 index, aspartate aminotransferase to platelet ratio index and hyaluronic acid), and skeletal muscle mass and to investigate factors linked to skeletal muscle mass loss (SMML) in patients with chronic hepatitis C (CHC, n = 277, median age = 64 years). We defined patients with psoas muscle index [PMI, sum of bilateral psoas muscle mass calculated by manual trace method at the lumber 3 level on the computed tomography images divided by height squared (cm/m)] less than 6...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29300681/physical-chemical-properties-and-cell-toxicity-of-sanding-copper-treated-lumber
#6
Jennifer D Sisler, Chaolong Qi, Walter McKinney, Justine Shaffer, Michael Andrew, Taekhee Lee, Treye Thomas, Vincent Castranova, Robert R Mercer, Yong Qian
To protect against decay and fungal invasion into the wood, the micronized copper, copper carbonate particles, has been applied in the wood treatment in recent years; however, there is little information on the health risk associated with sanding micronized copper- treated lumber. In this study, wood dust from the sanding of micronized copper azole -treated lumber (MCA) was compared to sanding dust from solubilized copper azole-treated wood (CA-C) and untreated yellow pine (UYP). The test found that sanding MCA released a much higher concentration of nanoparticles than sanding CA-C and UYP, and the particles between about 0...
January 4, 2018: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/29299274/cryptic-genetic-variation-in-an-inbreeding-and-cosmopolitan-pest-xylosandrus-crassiusculus-revealed-using-ddradseq
#7
Caroline Storer, Adam Payton, Stuart McDaniel, Bjarte Jordal, Jiri Hulcr
Each year new exotic species are transported across the world through global commerce, causing considerable economic and ecological damage. An important component of managing invasion pathways is to identify source populations. Some of the most widespread exotic species are haplodiploid ambrosia beetles. The ability to mate with siblings (inbreed) and their transportable food source (symbiotic fungus) have enabled them to colonize most of the world and become pests of plant nurseries, lumber, and forests. One of the fastest spreading ambrosia beetles is Xylosandrus crassiusculus...
December 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29283087/the-preoperative-sarcopenia-status-is-associated-with-lymphovascular-invasion-in-upper-tract-urothelial-carcinoma-patients-treated-with-radical-nephroureterectomy
#8
Tadatsugu Anno, Eiji Kikuchi, Keishiro Fukumoto, Koichiro Ogihara, Mototsugu Oya
INTRODUCTION: Sarcopenia is a novel concept representing skeletal muscle wasting and has been identified as a prognostic factor for several cancers. The aims of this study were to evaluate the prognostic significance of sarcopenia and the relationship between sarcopenia and poor pathological findings in upper tract urothelial carcinoma (UTUC) patients who underwent radical nephroureterectomy (RNU). METHODS: We identified 123 UTUC patients who underwent RNU between 2003 and 2014...
December 22, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29262477/-clinical-analysis-of-four-cases-of-anti-gq1b-syndrome
#9
X Y Yang, T L Han, W H Zhang, S Zhang, F Fang
Objective: To investigate the clinical manifestations, laboratory findings, treatment and outcome of anti-GQ1b antibody syndrome. Method: The clinical manifestations, laboratory examination, diagnosis, treatment and prognosis of (4 patients 4 male patients, from 4 to 12 years) with anti-GQ1b syndrome in Beijing Children's Hospital affiliated to Capital Medical University from 2015 to 2016 were retrospectively analyzed. Result: All 4 children presented with ataxia. Case 1 showed impaired speech, ptosis and weakness of arms; case 2 and 3 had external ophthalmoplegia, weakness of limbs; case 4 presented hypersomnia, irritability and hallucinations...
December 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29239253/fifty-top-cited-spine-articles-from-mainland-china-a-citation-analysis
#10
Yaohong Wu, Yachao Zhao, Linghan Lin, Zhijun Lu, Zhaoyang Guo, Xiaoming Li, Rongchun Chen, Huasong Ma
Objective To identify the 50 top-cited spine articles from mainland China and to analyze their main characteristics. Methods Web of Science was used to identify the 50 top-cited spine articles from mainland China in 27 spine-related journals. The title, year of publication, number of citations, journal, anatomic focus, subspecialty, evidence level, city, institution and author were recorded. Results The top 50 articles had 29-122 citations and were published in 11 English-language journals; most (32) were published in the 2000s...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/29230636/predictors-of-improvement-in-bone-mineral-density-after-celiac-disease-diagnosis
#11
Haley M Zylberberg, Benjamin Lebwohl, Arindam RoyChoudhury, Marcella D Walker, Peter H R Green
PURPOSE: Low bone density is frequently found in patients newly diagnosed with celiac disease (CD), and improvement is variable. This study was performed to assess changes in bone mineral density (BMD) by dual x-ray absorptiometry (DXA) at the lumbar spine, hip, and distal one-third radius as well as clinical predictors of BMD changes after the diagnosis and treatment of CD. METHODS: Adult CD patients who had serial DXA at the Celiac Disease Center at Columbia University Medical Center were included (N = 103)...
December 11, 2017: Endocrine
https://www.readbyqxmd.com/read/29217859/efficacy-of-transdermal-buprenorphine-patch-on-post-operative-pain-relief-after-elective-spinal-instrumentation-surgery
#12
Saikat Niyogi, Pratibha Bhunia, Jisnu Nayak, Sankari Santra, Amita Acharjee, Indrani Chakraborty
Background and Aims: Transdermal buprenorphine patch (TDB) is increasingly used for chronic pain management because of non-invasive dosing, longer duration of action and minimal side effects. However its role in acute post-operative pain management for spinal instrumentation surgery is not well established. The aim of this study was to evaluate the analgesic efficacy of buprenorphine patch for postoperative pain relief in patients undergoing spinal instrumentation surgery. Methods: In this randomised, placebo-controlled, double-blinded, prospective study, 70 adult patients undergoing elective spinal instrumentation surgery were randomly allocated into two groups-TDB Group (buprenorphinepatch) and TDP Group (placebo patch)...
November 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/29208859/an-evaluation-of-the-result-of-fenestration-and-discectomy-for-the-treatment-of-prolapsed-lumber-intervertrebal-disc-plid
#13
M A Islam, S I Akon, M Shamsuzzaman, M Asaduzzaman, S Akter, M A Awal, A H Mahboob, M S Islam, M M Rahman, R Ara, M K Alam, M R Ali
The aim of this study is to asses the result of fenestration and discectomy for the treatment of PLID. This Prospective quasi experimental study was conducted on 29 Patient of PLID with different ages at Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh from July 2014 to June 2016. Post Operative outcome was assessed through Modified Macnab Criteria & Visual Analogue Score (VAS). The mean age of patient were 38.14±9.20 years and ranging from 24 to 55 years. The mean age of male was 37.21±9.72 years and female patient was 39...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29139137/potential-exposure-and-cancer-risk-from-formaldehyde-emissions-from-installed-chinese-manufactured-laminate-flooring
#14
Patrick Sheehan, Ankur Singhal, Kenneth T Bogen, David MacIntosh, Renee M Kalmes, John McCarthy
Lumber Liquidators (LL) Chinese-manufactured laminate flooring (CLF) has been installed in >400,000 U.S. homes over the last decade. To characterize potential associated formaldehyde exposures and cancer risks, chamber emissions data were collected from 399 new LL CLF, and from LL CLF installed in 899 homes in which measured aggregate indoor formaldehyde concentrations exceeded 100 μg/m(3) from a total of 17,867 homes screened. Data from both sources were combined to characterize LL CLF flooring-associated formaldehyde emissions from new boards and installed boards...
November 15, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/29116651/probing-the-effect-of-polymer-molecular-weight-on-penetration-into-the-wood-cell-wall-using-polyethylenimine-pei-as-a-model-compound
#15
Brian Dorvel, Praveenkumar Boopalachandran, Ida Chen, Andrew Bowling, Kerry Williams, Steve King
Decking is one of the largest applications for the treated wood market. The most challenging property to obtain for treated wood is dimensional stability, which can be achieved, in part, by cell wall bulking, cell wall polymer crosslinking and removal of hygroscopic components in the cell wall. A commonly accepted key requirement is for the actives to infuse through the cell wall, which has a microporosity of ∼5-13 nm. Equally as challenging is being able to measure and quantify the cell wall penetration...
November 8, 2017: Journal of Microscopy
https://www.readbyqxmd.com/read/29095561/tropical-wood-resistance-to-the-west-indian-drywood-termite-cryptotermes-brevis-if-termites-can-t-chew%C3%A2
#16
Lírio Cosme, Marcelo M Haro, Nelsa Maria P Guedes, Terezinha Maria C Della Lucia, Raul Narciso C Guedes
BACKGROUND: The importance and impact of invasive species are usually considered based on their economic implications, particularly their direct damage. The West Indian drywood termite Cryptotermes brevis (Walker) is an example and concern in structural lumber, furniture, and other wood products. Despite its importance, its tropical wood preferences and wood physical characteristics contributing to resistance were not yet investigated. Here we developed wood testing units to allow the X-ray recording of termite colonization and then subsequently tested tropical wood resistance to the termite through free-choice and no-choice bioassays using these wood testing units...
November 2, 2017: Pest Management Science
https://www.readbyqxmd.com/read/29067769/differences-in-skeletal-muscle-loss-caused-by-cytotoxic-chemotherapy-and-molecular-targeted-therapy-in-patients-with-advanced-non-small-cell-lung-cancer
#17
Kazutaka Kakinuma, Hazime Tsuruoka, Kei Morikawa, Naoki Furuya, Takeo Inoue, Teruomi Miyazawa, Masamichi Mineshita
BACKGROUND: Recent studies have revealed a reduction in the skeletal muscle area in patients with advanced non-small cell lung cancer (NSCLC) after chemotherapy. EGFR and ALK tyrosine kinase inhibitor (TKI)-based therapies are less cytotoxic than chemotherapy, but differences in skeletal muscle mass between patients receiving EGFR and ALK TKI therapies and patients receiving cytotoxic chemotherapy have not yet been reported. METHODS: Data of pathologically proven NSCLC patients were reviewed, and chest computed tomography and/or positron emission tomography-computed tomography images obtained from January 2012 to December 2014 were selected...
October 25, 2017: Thoracic Cancer
https://www.readbyqxmd.com/read/28993571/job-safety-analysis-and-hazard-identification-for-work-accident-prevention-in-para-rubber-wood-sawmills-in-southern-thailand
#18
Phayong Thepaksorn, Supawan Thongjerm, Salee Incharoen, Wattasit Siriwong, Kouji Harada, Akio Koizumi
OBJECTIVE: We utilized job safety analysis (JSA) and hazard identification for work accident prevention in Para rubber wood sawmills, which aimed to investigate occupational health risk exposures and assess the health hazards at sawmills in the Trang Province, located in southern Thailand. METHODS: We conducted a cross-sectional study which included a walk-through survey, JSA, occupational risk assessment, and environmental samplings from March through September 2015 at four Para rubber wood sawmills...
October 7, 2017: Journal of Occupational Health
https://www.readbyqxmd.com/read/28971381/measurement-of-mechanical-withdrawal-thresholds-and-gait-analysis-using-the-catwalk-method-in-a-nucleus-pulposus-applied-rodent-model
#19
Takuya Kameda, Yoichi Kaneuchi, Miho Sekiguchi, Shin-Ichi Konno
BACKGROUND: There are some previous reports of gait analysis using a rodent pain model. Applying the CatWalk method, objective measurements of pain-related behavior could be evaluated, but this method has not been investigated using the nucleus pulposus (NP) applied model, which was developed as a model of lumber disc herniation. We aimed to measure mechanical withdrawal thresholds and analyze gait patterns using the CatWalk method for the evaluation of the pain-related behavior caused by NP application...
September 29, 2017: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/28962603/assessment-of-intracranial-pressure-with-ultrasonographic-retrobulbar-optic-nerve-sheath-diameter-measurement
#20
Dachuan Liu, Zhen Li, Xuxiang Zhang, Liping Zhao, Jianping Jia, Fei Sun, Yaxing Wang, Daqing Ma, Wenbin Wei
BACKGROUND: Ultrasonograpic retrobulbar optic nerve sheath diameter (ONSD) measurement is considered to be an alternative noninvasive method to estimate intracranial pressure,but the further validation is urgently needed. The aim of the current study was to investigate the association of the ultrasonographic ONSD and intracranial pressure (ICP) in patients. METHODS: One hundred and ten patients whose intracranial pressure measured via lumbar puncture were enrolled in the study...
September 29, 2017: BMC Neurology
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