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Ru-Sen Zhu, Yi-Ming Ren, Jian-Jun Yuan, Zi-Jian Cui, Jun Wan, Bao-You Fan, Wei Lin, Xian-Hu Zhou, Xue-Li Zhang
Lumbar disc herniation (LDH) is a common disease and lumbar discectomy is the most common surgical procedure carried out for patients with low back pain and leg symptoms. Although most researchers are focusing on the surgical techniques during operation, the aim of this study is to evaluate the effect of local intervertebral lavage during microdiscectomy.In this retrospective study, 410 patients were operated on by microdiscectomy for LDH during 2011 to 2014. Retrospectively, 213 of them (group A) accepted local intervertebral irrigation with saline water before wound closure and 197 patients (group B) only had their operative field irrigated with saline water...
October 2016: Medicine (Baltimore)
Joseph Cadman, Chester Sutterlin, Danè Dabirrahmani, Richard Appleyard
BACKGROUND: Commercial fusion cages typically provide support in the central region of the endplate, failing to utilize the increased compressive strength around the periphery. This study demonstrates the increase in compressive strength that can be achieved if the bony periphery of the endplate is loaded. METHODS: Sixteen cadaveric lumbar vertebrae (L1-L5) were randomly divided into two even groups. A different commercial mass produced implant (MPI) was allocated to each group: (I) a Polyether-ether-ketone (PEEK) anterior lumber inter-body fusion (ALIF) MPI; and (II) a titanium ALIF MPI...
September 2016: J Spine Surg
Grace Hubert, Theresa Tam Chung, Connie Prosser, Dale Lien, Justin Weinkauf, Neil Brown, Marianne Goodvin, Kathy Jackson, Joan Tabak, Josette Salgado, Abeer Salman Alzaben, Diana R Mager
PURPOSE: Patients with cystic fibrosis (CF) often experience low bone mineral density (BMD) pre- and post-lung transplantation (LTX). The study purpose was to describe BMD and micronutrient status in adults with CF pre- and post-LTX. METHODS: Twelve patients with CF (29 ± 8 years) were recruited from the CF clinic at the University of Alberta Lung Transplant Program. BMD and vitamins A, D, E, K status, and parathyroid hormone were measured pre- and post-LTX. RESULTS: No significant differences pre- and post-LTX were observed at the different bone sites measured (lumber-spine, femoral-neck (FN), hip, and femoral-trochlea) (P > 0...
July 19, 2016: Canadian Journal of Dietetic Practice and Research
Abolfazl Firouzian, Afshin Gholipour Baradari, Abbas Alipour, Amir Emami Zeydi, Alieh Zamani Kiasari, Seyed Abdollah Emadi, Behrooz Kheradmand, Kaveh Hadadi
BACKGROUND: Lumbar discectomy is one of the most commonly performed neurosurgical procedures. Many patients experience postoperative pain after lumbar discectomy. This study evaluated the effect of ultra-low-dose naloxone infusion on pain intensity after lumbar discectomy in individuals receiving patient-controlled analgesia (PCA) with morphine. MATERIALS AND METHODS: In a double-blind, randomized, controlled trial, a total of 80 patients scheduled for open discectomy was randomly assigned to receive naloxone (group N) or placebo (group P)...
September 26, 2016: Journal of Neurosurgical Anesthesiology
Mark Moldavsky, Pavel Neumann, Noelle Klocke, Mir Hussain, Brandon S Bucklen
PURPOSE: Lateral lumbar disc prosthesis (LLDP) is an innovative device used to restore motion in select patients through a lateral retroperitoneal approach. No in vitro biomechanical studies have been published. Further, the potential for in toto circumferential joint restoration when use of this anterior disc is combined with facet replacement remains unqualified but signifies a potentially interesting clinical direction. METHODS: Researchers conducted a biomechanical feasibility study of an LLDP designed to investigate parameters of disc sizing used with bilateral facet joint replacement in a cadaveric model...
September 26, 2016: European Spine Journal
Kevin Phan, Joshua Xu, Daniel B Scherman, Prashanth J Rao, Ralph J Mobbs
STUDY DESIGN: A systematic review and meta-analysis OBJECTIVE.: To investigate the outcomes of anterior lumber interbody fusion (ALIF) with and without an "access surgeon". SUMMARY OF BACKGROUND DATA: Anterior approaches for spine operations have become increasingly popular but may often involve unfamiliar anatomy and territory for spine surgeons, potentially placing the patient at risk to a greater proportion of approach-related complications. Thus many spine surgeons require or prefer the assistance of an "access surgeon" to perform the exposure...
September 23, 2016: Spine
Iman M Bilto, Georg Hausner
BACKGROUND: Based on previous studies, it was suspected that the mitochondrial rns gene within the Ophiostomatales is rich in introns. This study focused on a collection of strains representing Ophiostoma piliferum, Ophiostoma pluriannulatum and related species that cause blue-stain; these fungi colonize the sapwood of trees and impart a dark stain. This reduces the value of the lumber. The goal was to examine the mtDNA rns intron landscape for these important blue stain fungi in order to facilitate future annotation of mitochondrial genomes (mtDNA) and to potentially identify mtDNA introns that can encode homing endonucleases which may have applications in biotechnology...
2016: SpringerPlus
Seeta A Sistla, Adam B Roddy, Nicholas E Williams, Daniel B Kramer, Kara Stevens, Steven D Allison
Tropical forest conversion to pasture, which drives greenhouse gas emissions, soil degradation, and biodiversity loss, remains a pressing socio-ecological challenge. This problem has spurred increased interest in the potential of small-scale agroforestry systems to couple sustainable agriculture with biodiversity conservation, particularly in rapidly developing areas of the tropics. In addition to providing natural resources (i.e. food, medicine, lumber), agroforestry systems have the potential to maintain higher levels of biodiversity and greater biomass than lower diversity crop or pasture systems...
2016: PloS One
Ozgur Yagan, Kadir Özyilmaz, Ahmet Özmaden, Özgür Sayin, Volkan Hanci
Stiff Person Syndrome (SPS), typified by rigidity in muscles of the torso and extremities and painful episodic spasms, is a rare autoimmune-based neurological disease. Here we present the successful endotracheal intubation and application of TIVA without muscle relaxants on an SPS patient. A 46 years old male patient was operated with ASA-II physical status because of lumber vertebral compression fracture. After induction of anesthesia using lidocaine, propofol and remifentanil tracheal intubation was completed easily without neuromuscular blockage...
September 2016: Brazilian Journal of Anesthesiology
Jia-Ming Liu, Xuan-Yin Chen, Yang Zhou, Xin-Hua Long, Wen-Zhao Chen, Zhi-Li Liu, Shan-Hu Huang, Hao-Qun Yao
Surgical intervention is an important option for treating spinal tuberculosis. Previous studies have reported different surgical procedures and bone grafts for it. To our knowledge, few studies demonstrated the clinical results of using nonstructural autogenous bone graft in surgical treatment of spinal tuberculosis.The purpose of this study is to compare the clinical outcomes of surgical management lumbar spinal tuberculosis by one-stage posterior debridement with nonstructural autogenous bone grafting and instrumentation versus anterior debridement, strut bone grafting combined with posterior instrumentation...
August 2016: Medicine (Baltimore)
Joseph C H Wong, Lawrence M Hanks
Because larvae of cerambycid beetles feed within woody plants, they are difficult to detect, and are readily transported in lumber and other wooden products. As a result, increasing numbers of exotic cerambycid species are being introduced into new regions of the world through international commerce, and many of these species pose a threat to woody plants in natural and managed forests. There is a great need for effective methods for detecting exotic and potentially invasive cerambycid species, and for monitoring native species for conservation purposes...
October 2016: Journal of Economic Entomology
Christopher J Demaree, Jose M Soliz, Rodolfo Gebhardt
INTRODUCTION:  Lumber punctures are a common procedure in patients with cancer. However, a potential complication of a lumbar puncture is a postdural puncture headache. The risk of neoplastic seeding to the central nervous system has led to concern over performing epidural blood patches (EBPs) for the treatment of postdural puncture headaches in patients with cancer. The goal of this retrospective study was to evaluate cancer seeding in the central nervous system in patients diagnosed with leukemia or lymphoma...
August 24, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Toshiya Tachibana, Keishi Maruo, Shinichi Inoue, Fumihiro Arizumi, Kazuki Kusuyama, Shinichi Yoshiya
The objectives of this study were to examine the diagnostic accuracy of pain drawing (PD) in determining the level of involvement and to investigate how the quantitative evaluation results of PD using a grid score (GS) correlates with the results of other clinical evaluation measures in diagnosis and assessment of patients with lumber disc herniation (LDH) involving a single nerve root. Thirty-one patients with single level LDH who were diagnosed and conservatively treated by the first author constituted the study population...
2016: SpringerPlus
Yvonne A Eiby, Nicole Y Shrimpton, Ian M R Wright, Eugenie R Lumbers, Paul B Colditz, Greg J Duncombe, Barbara E Lingwood
BACKGROUND: The preterm newborn is at high risk of developing cardiovascular compromise during the first day of life and this is associated with increased risk of brain injury. Standard treatments are volume expansion and administration of inotropes, typically dopamine and/or dobutamine, but there is limited evidence that inotropes improve clinical outcomes. This study investigated the efficacy of dopamine and dobutamine for the treatment of cardiovascular compromise in the preterm newborn using a piglet model...
August 31, 2016: Pediatric Research
Tadashi Okano, Kentaro Inui, Masahiro Tada, Yuko Sugioka, Kenji Mamoto, Shigeyuki Wakitani, Tatsuya Koike, Hiroaki Nakamura
OBJECTIVES: Osteoporosis is one of the complications in patients with rheumatoid arthritis (RA). In this study, we researched the morbidity of existing vertebral fractures and the risk factors for vertebral fractures in patients with RA. METHODS: This study included 413 participants, 208 patients with RA, and 205 age- and sex-matched controls without RA. Clinical data, radiographic assessment of vertebral fracture from T4 to L4 in thoracic and lumber spine, bone mineral density (BMD), and bone metabolic markers (BMM) were analyzed...
August 2, 2016: Modern Rheumatology
Masahiro Ohsawa, Kei-Ichiro Ishikura, Junpei Mutoh, Hiroaki Hisa
Small molecular G-protein plays a key role in several diseases. This study was designed to reveal the role of RhoA signaling in the pathophysiology of neuropathic pain in mice. Partial sciatic nerve injury caused thermal hyperalgesia, mechanical allodynia, and increased plasma membrane translocation of RhoA in the lumber spinal cord. GFAP-immunoreactivity (ir), Iba-1-ir, and Rho kinase 2 (ROCK2-ir) was also increased in the ipsilateral spinal dorsal horn of nerve-ligated mice. Moreover, partial nerve ligation increased the expression of phosphorylated myristoylated alanine-rich protein kinase C substrate (MARCKS)-ir in the ipsilateral spinal dorsal horn...
October 1, 2016: Neuroscience
I Ka, M L Gueye, O Thiam, L G Akpo, A O Toure
Strangulated lumbar hernia is a very rare condition, with no more than 30 cases reported in the literature so far. Therefore, there is no specific management guideline and the diagnosis remains difficult. By reporting the case of a Senegalese male patient who had a preoperative diagnosis of strangulated lumbar hernia, we aim to discuss the diagnosis and therapeutic modalities of this rare entity, which is often misdiagnosed.
July 14, 2016: Annals of the Royal College of Surgeons of England
Aysegul Ozdemir Ovalioglu, Erhan Emel, Emre Tacyildiz, Cem Ovalioglu, Muslum Gunes, Levent Uysal, Aysegul Esen Aydin
INTRODUCTION: We aimed to evaluate the efficacy of the transspinous approach compared with the conventional laminectomy in degenerative lumber spinal stenosis with or without disc herniations. METHODS: Clinical data of the 198 patients, operated on between April 2011 and June 2015 for degenerative lumber spinal stenosis, were analyzed retrospectively. Patients were classified into 2 groups according to the type of surgery either conventional laminectomy (group I; 101 patients) or the transspinous approach (group II; 97 patients)...
August 2016: Neurosurgery
V E Novikov, V S Oganov, O E Kabitskaya, L M Murashko, V P Naidina, E A Chernikhova
Investigations of the bone system and body composition in Mars-500 test-subjects (prior to and on completion of the experiment) involved dual-energy X-ray absorptiometry (DXA) using the HOLOGIC Delphy densitometer and the protocol performed to examine cosmonauts. Bone density of lumber vertebrae and femoral proximal epiphysis, and body composition were measured. Reliable changes in vertebral density found in 3 test-subjects displayed different trends from +2.6 to -2.4%. At the same time, the experiment decreased significantly mineral density of the femoral proximal epiphysis, including the neck, in all test-subjects...
2016: Aviakosmicheskaia i Ekologicheskaia Meditsina, Aerospace and Environmental Medicine
Le Huang, Yong-Ke You, Tracy Y Zhu, Li-Zhen Zheng, Xiao-Ru Huang, Hai-Yong Chen, Dong Yao, Hui-Yao Lan, Ling Qin
This study aimed to evaluate the validation of the leptin receptor-deficient mice model for secondary osteoporosis associated with type 2 diabetes mellitus (T2DM) at bone micro-architectural level. Thirty three 36-week old male mice were divided into four groups: normal control (db/m) (n = 7), leptin receptor-deficient T2DM (db/db) (n = 8), human C-reactive protein (CRP) transgenic normal control (crp/db/m) (n = 7), and human CRP transgenic T2DM (crp/db/db) (n = 11). Lumber vertebrae (L5) and bilateral lower limbs were scanned by micro-CT to analyze trabecular and cortical bone quality...
2016: Scientific Reports
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