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F J García-Gómez, I Acevedo-Báñez, R Martínez-Castillo, J L Tirado-Hospital, J I Cuenca-Cuenca, V M Pachón-Garrudo, R M Álvarez-Pérez, R García-Jiménez, E Rivas-Infante, J S García-Morillo, I Borrego-Dorado
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocitosis, characterized by multisystemic xanthogranulomatous infiltration by foamy histiocytes that stain positively for CD68 marker but not express CD1a and S100 proteins. Etiology and pathogenesis are still unknown and only about 500 cases are related in the literature. Multisystemic involvement leads to a wide variety of clinical manifestations that results in a poor prognosis although recent advances in treatment. We present the clinical, nuclear medicine findings and therapeutic aspects of a serie of 6 patients with histopathological diagnosis of ECD, who have undergone both bone scintigraphy (BS) and 18F-fluorodeoxyglucose (18FDG)-PET/CT scans in our institution...
August 2015: European Journal of Radiology
G L Cascini, V Cuccurullo, L Mansi
The use of somatostatin (SS) analogues in humans takes advantage by the availability of many related chemical forms that can be used for receptor therapy and, after radiolabelling, for diagnostic imaging and radionuclide therapy. The first proposed radiocompound, yet clinically widely diffuse, has been (111)In-octreotide (OCT), followed by positron emission tomography (PET) and beta emitter tracers. The main field of clinical applications is in neuroendocrine tumours (NET), starting by the demonstration of SS receptors (SSR) on the majority of NET, particularly on gastroenteropancreatic (GEP) tumours...
February 2010: Quarterly Journal of Nuclear Medicine and Molecular Imaging
J M Hernández Pérez, T Franquet Casas, S Rodríguez, A Giménez
The Langerhans' cell histiocytosis (LCH), also known as Histiocitosis X it is an illness not very frequent granulomatosus etiology not clarified yet, that it can have different manifestations and localizations, however the thymic localization as initial and exclusive place gives presentation HCL it is quite unusual. The present case is presented a patient that debuted with a clinical unspecific, where the tests give image they put she gives apparent a mass in previous mediastinum and that after the pathologic and immunohistochemical analysis they evidenced a proliferation Langerhans s cells and eosinophils it being positive for CD1a and S-100 confirming the diagnosis of the LCH...
October 2007: Anales de Medicina Interna: Organo Oficial de la Sociedad Española de Medicina Interna
Vitor Sousa, Lina Carvalho
DIP (desquamative interstitial pneumonia) is an interstitial lung disease with diffuse and uniform accumulation of alveolar macrophages. There is a strong association with tobacco since 90% of the patients are smokers. The interstitial lung diseases related to tobacco are diverse and include tumours, emphysema, chronic bronchitis, RBILD (Respiratory Bronchilites associated Interstitial Lung Disease), DIP and Langerhans Cell Histiocitosis. The authors present a case of DIP. A brief theorycal revision and discussion of a case is made facing the association with tobacco...
September 2004: Revista Portuguesa de Pneumologia
J E Cerdas, R P Evans, A S Mejido, J P Escalante, R A Acuña Bonilla
No abstract text is available yet for this article.
January 1973: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
R M Brugues, J L Vives-Corrons, C Rozman, J M Jou, J L Aguilar, F Cardellach, A Urbano, E Feliu
The hemophagocytosis or the process of ingestion of blood cells by phagocytes and macrophages of the mononuclear phagocytic system (MFS), is a phenomenon that rarely could be observed in the morphological examination of the bone marrow aspirate. Occasionally it is present in certain pathologic conditions such as, malignant histiocitosis, autimmune hemolytic anemia, or some chronic inflammatory diseases. The capacity of ingestion is not an exlusive property of the phagocytes and macrophages of the MFS, so that different neoplastic cells can show it too...
December 15, 1979: Medicina Clínica
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