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https://www.readbyqxmd.com/read/29316190/life-of-patients-10-years-after-a-successful-pediatric-intestinal-transplantation-in-europe
#1
Lorenzo Norsa, Girish Gupte, Esther Ramos Boluda, Francisca Joly, Olivier Corcos, Jacques Pirenne, Gustaf Herlenius, Florence Lacaille
A multicenter Europe-wide single point study in intestinal transplantation (ITx) centers was conducted to identify and describe patients surviving for more than 10 years after ITx in childhood. The health and nutritional status, care requirements and psychosocial status were recorded. Among 120 transplanted before 2005, 38 patients with a functioning graft were included. Thirty (79%) had an exclusive oral diet, 7 (18%) complimentary enteral nutrition for eating disorders, one a combination of parenteral and enteral nutrition...
January 9, 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/29314175/somatic-diversification-of-the-b-cell-repertoire-requires-two-cell-subsets
#2
Melvin Cohn
Evolution found itself in a Catch-22 situation when selecting for the somatically derived paratopic repertoire of the humoral immune system. The B-cell BCR repertoire can only be somatically diversified from a substrate of paratopes that is encoded in the germline. In order for the cells expressing that substrate to also be a target of germline selection, their BCRs must, independently, be of selective value by being expressed in a functionally important way in each individual. A somatically derived repertoire scrambles this substrate so that its specificities are lost, making it unselectable in the germline...
January 3, 2018: Scandinavian Journal of Immunology
https://www.readbyqxmd.com/read/29297368/the-bloody-mess-of-red-blood-cell-transfusion
#3
REVIEW
Susilo Chandra, Hrishikesh Kulkarni, Martin Westphal
Red blood cell (RBC) transfusion might be life-saving in settings with acute blood loss, especially uncontrolled haemorrhagic shock. However, there appears to be a catch-22 situation reflected by the facts that preoperative anaemia represents an independent risk factor for postoperative morbidity and mortality, and that RBC transfusion might also contribute to adverse clinical outcomes. This dilemma is further complicated by the difficulty to define the "best" transfusion trigger and strategy. Since one size does obviously not fit all, a personalised approach is merited...
December 28, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29241841/dorsal-wrist-plication-for-midcarpal-instability
#4
Herbert P von Schroeder
PURPOSE: Midcarpal instability (MCI) is a cause of chronic wrist pain for which treatment remains controversial. This study's purpose was to determine the outcome of a treatment algorithm for MCI that included immobilization and surgical interventions. METHODS: We prospectively enrolled 23 consecutive patients (12 males, average age 27 years) with 27 symptomatic wrists. All had generalized wrist pain with an average duration of 22 months. All had MCI and a catch-up clunk that reproduced the symptoms...
December 11, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29204224/bacteriology-and-antibiogram-of-urinary-tract-infection-among-female-patients-in-a-tertiary-health-facility-in-south-eastern-nigeria
#5
REVIEW
Angus N Oli, Vivian B Akabueze, Chijioke E Ezeudu, George U Eleje, Obiora S Ejiofor, Ifeanyichukwu U Ezebialu, Charlotte B Oguejiofor, Ifeoma M Ekejindu, George O Emechebe, Kenneth N Okeke
Background: Urinary Tract Infection (UTI) is a common contagion among men and women with the incidence relatively higher among women due to their differing anatomy. An understanding of the kind of pathogens implicated in urinary tract infections as well as antibiotic susceptibility profiling may help the clinician make rationally correct empirical choice in their treatment. Objective: This study is aimed at determining the type and antibiotic susceptibility pattern of bacterial uropathogens isolated from female patients attending Chukwuemeka Odumegwu Ojukwu University Teaching Hospital (COOUTH), Awka, Nigeria...
2017: Open Microbiology Journal
https://www.readbyqxmd.com/read/29178520/a-catch-22-interleukin-22-and-cancer
#6
REVIEW
Pedro Hernandez, Konrad Gronke, Andreas Diefenbach
Barrier surfaces of multicellular organisms are in constant contact with the environment and infractions to the integrity of epithelial surfaces is likely a frequent event. Interestingly, components of the immune system, that can be activated by environmental compounds such as the microbiota or nutrients, are interspersed among epithelial cells or directly underlie the epithelium. It is now appreciated that immune cells continuously receive and integrate signals from the environment. Curiously, such continuous reception of stimulation does not normally trigger an inflammatory response but mediators produced by immune cells in response to such signals seem to rather promote barrier integrity and repair...
November 27, 2017: European Journal of Immunology
https://www.readbyqxmd.com/read/29110951/valve-sparing-repair-to-alleviate-pulmonary-regurgitation-may-lead-to-as-much-right-ventricular-dilatation-as-a-transannular-patch-a-catch-22
#7
EDITORIAL
Tae-Jin Yun
No abstract text is available yet for this article.
October 7, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29110670/indoor-and-outdoor-malaria-vector-surveillance-in-western-kenya-implications-for-better-understanding-of-residual-transmission
#8
Teshome Degefa, Delenasaw Yewhalaw, Guofa Zhou, Ming-Chieh Lee, Harrysone Atieli, Andrew K Githeko, Guiyun Yan
BACKGROUND: The widespread use of indoor-based malaria vector control interventions has been shown to alter the behaviour of vectors in Africa. There is an increasing concern that such changes could sustain residual transmission. This study was conducted to assess vector species composition, feeding behaviour and their contribution to indoor and outdoor malaria transmission in western Kenya. METHODS: Anopheles mosquito collections were carried out from September 2015 to April 2016 in Ahero and Iguhu sites, western Kenya using CDC light traps (indoor and outdoor), pyrethrum spray catches (PSCs) (indoor) and pit shelters (outdoor)...
November 6, 2017: Malaria Journal
https://www.readbyqxmd.com/read/29104911/facile-synthesis-of-a-next-generation-safety-catch-acid-labile-linker-scal-2-suitable-for-solid-phase-synthesis-on-support-display-and-for-post-synthesis-tagging
#9
Christophe Portal, Martin Hintersteiner, Olivier Barbeau, Peter Dodd, Margaret Huggett, Irene Pérez-Pi, David Evans, Manfred Auer
The SCAL linker, a safety catch linker, is amongst the most versatile linkers for solid phase synthesis. It was originally described in 1991 by Pátek and Lebl. Yet, its application has been hindered by the low yields of published synthetic routes. Over time, the exceptional versatility of this linker has been demonstrated in several applications of advanced solid phase synthesis of peptides and peptidomimetics. Recently, an updated synthesis of the original linker has also been presented at the 22(nd) American Peptide Symposium, comprising 10 steps...
August 11, 2017: ChemistrySelect
https://www.readbyqxmd.com/read/29103197/optimization-of-fishing-for-stock-enhancement-of-rutilis-rutilus-and-scardinius-erythropththalmus-in-forage-fish-deficient-tunisian-reservoirs
#10
Sami Mili, Rym Ennouri, Houcine Laouar, Lotfi Aleya
Twenty specially designed fishing nets were used to catch broodstock of the forage fish roach and rudd (Rutilus rutilus and Scardinius erythrophthalmus). The monofilament gill nets were of different mesh sizes (18, 22, 24, and 26 mm) but of identical dimensions (4 × 50 m). The fish, caught in Sidi Salem reservoir in 2014, amounted to a total of 8901 roach and rudd caught at 41 different times; 3335 broodstock forage fish were transferred to 11 forage fish-deficient Tunisian reservoirs. The best yields (0...
November 4, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29045484/semi-field-assessment-of-the-bg-malaria-trap-for-monitoring-the-african-malaria-vector-anopheles-arabiensis
#11
Elis P A Batista, Halfan S Ngowo, Mercy Opiyo, Gasper K Shubis, Felician C Meza, Fredros O Okumu, Alvaro E Eiras
Odour-baited technologies are increasingly considered for effective monitoring of mosquito populations and for the evaluation of vector control interventions. The BG-Malaria trap (BGM), which is an upside-down variant of the widely used BG-Sentinel trap (BGS), has been demonstrated to be effective to sample the Brazilian malaria vector, Anopheles darlingi. We evaluated the BGM as an improved method for sampling the African malaria vectors, Anopheles arabiensis. Experiments were conducted inside a large semi-field cage to compare trapping efficiencies of BGM and BGS traps, both baited with the synthetic attractant, Ifakara blend, supplemented with CO2...
2017: PloS One
https://www.readbyqxmd.com/read/29040780/fear-boosts-the-early-neural-coding-of-faces
#12
Maria Teresa Turano, Junpeng Lao, Anne-Raphaëlle Richoz, Peter de Lissa, Sarah Belinda Aimée Degosciu, Maria Pia Viggiano, Roberto Caldara
The rapid extraction of facial identity and emotional expressions is critical for adapted social interactions. These biologically relevant abilities have been associated with early neural responses on the face sensitive N170 component. However, whether all facial expressions uniformly modulate the N170, and whether this effect occurs only when emotion categorization is task-relevant, is still unclear. To clarify this issue, we recorded high-resolution electrophysiological signals while 22 observers perceived the six basic expressions plus neutral...
October 10, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/29036392/update-from-the-advisory-committee-on-immunization-practices
#13
Sean T O'Leary, David W Kimberlin
The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts, meets 3 times per year to develop recommendations for vaccine use in the United States. The group has 15 voting members, and each member's term is 4 years. ACIP members and Centers for Disease Control and Prevention (CDC) staff discuss the epidemiology of vaccine-preventable diseases and vaccine research, effectiveness, safety data, and clinical trial results. Representatives from the American Academy of Pediatrics (Carrie L...
September 25, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28972820/injuries-in-cricket
#14
Dinshaw N Pardiwala, Nandan N Rao, Ankit V Varshney
CONTEXT: Cricket is a popular global sport that requires a combination of physical fitness, skill, and strategy. Although a noncontact sport, overuse and impact injuries are common since players engage in a wide range of physical activities, including running, throwing, batting, bowling, catching, and diving. Significant or match time-loss injuries are defined as those that either prevent a player from being fully available for selection in a major match, or during a major match, cause a player to be unable to bat, bowl, or keep wicket when required by either the rules or the team's captain...
September 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28899211/factorial-validity-of-the-movement-assessment-battery-for-children-2nd-edition-mabc-2-in-7-16-year-olds
#15
Rudolf Psotta, Reza Abdollahipour
The Movement Assessment Battery for Children-2nd Edition (MABC-2) is a test of motor development, widely used in clinical and research settings. To address which motor abilities are actually captured by the motor tasks in the two age versions of the MABC-2, the AB2 for 7- 10-year-olds and the AB3 for 11- 16-year-olds, we examined AB2 and AB3 factorial validity. We conducted confirmatory factor analysis (SPSS AMOS 22.0) on data from the test's standardization samples of children aged 7-10, n = 483, and 11-16, n = 674, in order to find the best fitting models...
January 1, 2017: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/28886724/composition-of-anopheles-mosquitoes-their-blood-meal-hosts-and-plasmodium-falciparum-infection-rates-in-three-islands-with-disparate-bed-net-coverage-in-lake-victoria-kenya
#16
Edwin Ogola, Jandouwe Villinger, Danspaid Mabuka, David Omondi, Benedict Orindi, James Mutunga, Vincent Owino, Daniel K Masiga
BACKGROUND: Small islands serve as potential malaria reservoirs through which new infections might come to the mainland and may be important targets in malaria elimination efforts. This study investigated malaria vector species diversity, blood-meal hosts, Plasmodium infection rates, and long-lasting insecticidal net (LLIN) coverage on Mageta, Magare and Ngodhe Islands of Lake Victoria in western Kenya, a region where extensive vector control is implemented on the mainland. RESULTS: From trapping for six consecutive nights per month (November 2012 to March 2015) using CDC light traps, pyrethrum spray catches and backpack aspiration, 1868 Anopheles mosquitoes were collected...
September 8, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28864902/fatty-acid-composition-of-odonate-s-eyes
#17
N N Sushchik, O N Popova, O N Makhutova, M I Gladyshev
We have studied the fatty acid composition of eyes of amphibiotic insects, namely, the odonate Sympetrum flaveolum. The main polyunsaturated fatty acid of odonate's eyes has been found to be 20:5n-3 (eicosapentaenoic fatty acid, EPA) rather than 18:2n-6 and 18:3n-3, which usually dominate in eyes of terrestrial insects, or 22:6n-3, which dominates in eyes of vertebrates. The prevalence of EPA in odonate's eyes probably provides a more effective transmission of light signal in this animal compared to terrestrial insects...
July 2017: Doklady. Biochemistry and Biophysics
https://www.readbyqxmd.com/read/28841696/trans-regional-migration-of-the-beet-armyworm-spodoptera-exigua-lepidoptera-noctuidae-in-north-east-asia
#18
Xiaowei Fu, Hongqiang Feng, Zhongfang Liu, Kongming Wu
The beet armyworm, Spodoptera exigua (Hübner) (Lepidoptera: Noctuidae), is a serious polyphagous insect pest worldwide. This species is known as a long-distance migrant, and previous studies on its migration have been mostly carried out in regions where it can overwinter. However, what pattern of seasonal migration this species exhibits in regions where it cannot overwinter (i.e., the 'summer breeding region') remains unknown. Here, we present data from 14-years of monitoring on a small remote island located in the center of the Bohai Strait, in northern China, by means of searchlight trapping and ovarian dissection...
2017: PloS One
https://www.readbyqxmd.com/read/28826566/growth-hormone-activates-hepatic-and-cerebral-cholesterol-metabolism-in-small-for-gestational-age-children-without-catch-up-growth
#19
Satoshi Hirayama, Hironori Nagasaka, Saori Nakagawa, Mayuko Takuwa, Mariko Nakacho, Tohru Yorifuji, Hiroki Kondou, Hirokazu Tsukahara, Ichiro Morioka, Akihito Ishida, Susumu Yamato, Takashi Miida
BACKGROUND: Growth hormone (GH) replacement therapy improves hypercholesterolemia in patients with GH deficiency, suggesting that GH modulates cholesterol metabolism. OBJECTIVES: We examined GH effects on lipid profiles and cholesterol-related markers reflecting hepatic and cerebral cholesterol metabolism in small-for-gestational age (SGA) children without catch-up growth. METHODS: This study examined SGA children without catch-up growth (n = 22) and healthy children (controls, n = 11)...
July 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28805243/factors-associated-with-acceptance-of-pandemic-flu-vaccine-by-healthcare-professionals-in-spain-2009-2010
#20
Tania Fernández-Villa, Antonio J Molina, Nuria Torner, Jesus Castilla, Jenaro Astray, Susana García-Gutiérrez, José María Mayoral, Sonia Tamames, Ángela Domínguez, Vicente Martín
The A(H1N1)pdm09 influenza virus reached pandemic level in Spain in 2009, prompting a national vaccination campaign. To avoid transmission to patients, healthcare professionals' vaccination against pandemic influenza is crucial. The main objective of this study was to analyze factors associated with the failure by healthcare professionals to accept the pandemic vaccination in 2009. A cross-sectional survey was conducted of healthcare professionals in seven of Spain's autonomous regions. A questionnaire was used to collect information about personal and professional details, the respondents' flu vaccination status in the 2008-2009 and 2009-2010 seasons (seasonal and pandemic vaccines), and their knowledge and attitudes...
October 2017: Research in Nursing & Health
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