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https://www.readbyqxmd.com/read/29764247/survey-and-analysis-for-impact-factors-of-psychological-distress-in-hiv-infected-pregnant-women-who-continue-pregnancy
#1
Shouxue Qin, Yanping Tan, Bingyan Lu, Yuqing Cheng, Yanli Nong
OBJECTIVE: The objective of this study is to explore the psychological distress of HIV-infected pregnant women who continue pregnancy, and analyze the possible influencing factors. METHODS: A total of 194 HIV-infected pregnant women who continue pregnancy were enrolled for this study by a convenient sampling method during June 2012-August 2016. Participants completed questionnaires including Hospital Anxiety and Depression Scale (HADS), Berger HIV Stigma Scale (BHSS), Distress Thermometer (DT) and Problem List (PL), and to determine the cut-off value of DT in the group...
May 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29762164/cervical-cancer-screening-among-hiv-infected-women-in-an-urban-u-s-safety-net-healthcare-system
#2
Arti Barnes, Andrea C Betts, Eric K Borton, Joanne M Sanders, Sandi L Pruitt, Claudia Werner, Andres Bran, Carolee D Estelle, Bijal A Balasubramanian, Stephen J Inrig, Ethan A Halm, Celette Sugg Skinner, Jasmin A Tiro
OBJECTIVE: Little is known about cervical cancer screening and results patterns among HIV infected (HIV+) women in real-world healthcare settings. We characterized two periods of screening opportunity. DESIGN: Retrospective cohort. SETTING: U.S. safety-net healthcare system in Dallas County, Texas. SUBJECTS: We analyzed data from electronic medical records (EMR) of 1,490 HIV+ women receiving care 2010-2014. MAIN OUTCOME MEASURES: At baseline, we categorized a woman's Pap status 15 months prior to index date as under-screened (vs...
May 11, 2018: AIDS
https://www.readbyqxmd.com/read/29747725/cancer-in-pregnancy
#3
REVIEW
Anna McCormick, Erika Peterson
This article reviews some of the more common types of cancer that may be encountered during pregnancy. It reviews the unique challenges with the diagnosis and treatment of breast, cervical, hematologic, and colon cancers in pregnant patients.
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29740819/prophylactic-vaccination-against-human-papillomaviruses-to-prevent-cervical-cancer-and-its-precursors
#4
REVIEW
Marc Arbyn, Lan Xu, Cindy Simoens, Pierre Pl Martin-Hirsch
BACKGROUND: Persistent infection with high-risk human papillomaviruses (hrHPV) types is causally linked with the development of cervical precancer and cancer. HPV types 16 and 18 cause approximately 70% of cervical cancers worldwide. OBJECTIVES: To evaluate the harms and protection of prophylactic human papillomaviruses (HPV) vaccines against cervical precancer and HPV16/18 infection in adolescent girls and women. SEARCH METHODS: We searched MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL) and Embase (June 2017) for reports on effects from trials...
May 9, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29736193/the-potential-of-angiogenin-as-a-serum-biomarker-for-diseases-systematic-review-and-meta-analysis
#5
REVIEW
Dongdong Yu, Yikai Cai, Wei Zhou, Jinghao Sheng, Zhengping Xu
Background: Angiogenin (ANG) is a multifunctional angiogenic protein that participates in both normal development and diseases. Abnormal serum ANG levels are commonly reported in various diseases. However, whether ANG can serve as a diagnostic or prognostic marker for different diseases remains a matter of debate. Methods: Here, we performed a systematic review and meta-analysis of the literature utilizing PubMed, Web of Science, and Scopus search engines to identify all publications comparing plasma or serum ANG levels between patients with different diseases and healthy controls, as were studies evaluating circulating ANG levels in healthy populations, pregnant women, or other demographic populations...
2018: Disease Markers
https://www.readbyqxmd.com/read/29728277/breast-cancer-in-pregnant-patients-a-review-of-the-literature
#6
María Teresa Martínez, Begoña Bermejo, Cristina Hernando, Valentina Gambardella, Juan Miguel Cejalvo, Ana Lluch
Breast cancer diagnosed during pregnancy is a rare occurrence at present; however, in recent years a trend towards delayed childbirth is generating an increase in its incidence. This situation requires a multidisciplinary approach involving obstetricians, oncologists and surgeons. In this review we analyse diagnostic methods, different possible treatments and long-term patient prognosis. We conducted a search for articles published in PubMed, or in abstract form from the San Antonio Breast Cancer Symposium (SABCS), the European Society for Medical Oncology (ESMO), and the American Society of Clinical Oncology (ASCO) annual meeting, using the search terms: "Breast cancer and pregnancy"...
April 23, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29718697/znt2-is-critical-for-lysosome-acidification-and-biogenesis-during-mammary-gland-involution
#7
Olivia C Rivera, Stephen R Hennigar, Shannon L Kelleher
Mammary gland involution is a tightly regulated process of tissue remodeling by which a lactating mammary gland reverts to the pre-pregnant state, and is characterized by the most profound example of regulated epithelial cell death in normal tissue. Defects in the execution of involution are associated with lactation failure and breast cancer. Initiation of mammary gland involution requires upregulation of lysosomal biogenesis and acidification to activate lysosomal-mediated cell death (LCD); however, specific mediators of this initial phase of involution are not well-described...
May 2, 2018: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/29715049/pregnancy-achieved-using-donor-eggs-in-cancer-survivors-with-treatment-induced-ovarian-failure-obstetric-and-perinatal-outcome
#8
Anna Marklund, Josefine Nasiell, Ann-Sofie Berger, Antonia Fagerberg, Kenny A Rodriguez-Wallberg
BACKGROUND: Egg donation is a common fertility treatment in female cancer survivors with reproductive wish and iatrogenic ovarian failure. We examined whether women previously treated for cancer have a higher risk of pregnancy complications after egg donation treatments when compared to women without cancer history. METHODS: In this prospective cohort treated during 2003-2015 at a single center, 31 women with previous history of cancer achieved 25 deliveries and 212 women without cancer history achieved 244 deliveries...
May 1, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29699534/high-prevalence-of-hepatitis-b-infections-in-burkina-faso-1996-2017-a-systematic-review-with-meta-analysis-of-epidemiological-studies
#9
Moussa Lingani, Tomoyuki Akita, Serge Ouoba, Armel Moumini Sanou, Aya Sugiyama, Zekiba Tarnagda, Masayuki Ohisa, Halidou Tinto, Shunji Mishiro, Junko Tanaka
BACKGROUND: Hepatitis B virus (HBV) infection was long considered an important public health concern in Burkina Faso and still represents a major cause of liver cancer and cirrhosis in the active population. To counter the problem, a national strategic plan was developed and adopted in July 2017 to coordinate viral hepatitis elimination's efforts. However evidence to support its implementation remains scanty and scattered. The main purpose of this study was to summarize available information from per-reviewed articles published over the last two decades to accurately estimate the prevalence of HBV infection in Burkina Faso...
April 25, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29699376/digital-cervicography-by-simply-portable-device-as-an-alternative-test-for-cervical-cancer-screening-in-rural-area-of-thailand
#10
Nissana Singhakum, Somsak Laiwejpithaya, Pattama Chaopotong
Objective: Various screening methods for cervical cancer are proved to be effective in reducing such type of cancer. We aims to introduce a new portable device as an alternative method for cervical cancer screening. The performance of device was tested on the assessment of cervical lesions using cervicograph score with the cervical cytology. Methods: 325 non-pregnant women were tested from March 2013 to August 2015. The cervical and vaginal cells from the sample were collected for cytology, then all of them received the digital cervicography conducted with our new device and scored using cervicograph score...
April 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29692671/potassium-bromate-disrupts-mitochondrial-distribution-within-murine-oocytes-during-in-vitro-maturation
#11
Kenichi Yamada, Yuuki Hiradate, Mei Goto, Chiho Nishiyama, Kenshiro Hara, Hiroaki Yoshida, Kentaro Tanemura
Purpose: As disturbed mitochondrial distribution is thought to be a cause of the aging of oocytes, it was investigated whether oxidizing agents exert harmful effects on nuclear maturation and mitochondrial cluster formation in murine oocytes and whether antioxidants could rescue such harmful effects in vitro. Methods: Oocytes were obtained from female Institute of Cancer Research mice 48 h after an intraperitoneal injection of 7.5 IU pregnant mare serum gonadotropin...
April 2018: Reproductive Medicine and Biology
https://www.readbyqxmd.com/read/29683035/is-peripherally-inserted-central-catheter-related-thrombosis-associated-with-abo-blood-group-a-case-control-pilot-study
#12
Raad A Haddad, Yanal Alnimer, Ahmed Abdalla, Carlos F Ríos-Bedoya, Ghassan Bachuwa
Peripherally inserted central catheter (PICC) use is associated with many complications including line-related thrombosis. Several studies and meta-analyses confirmed the increased risk to develop venous thromboembolism in non-O blood group individuals. Our pilot study aimed to examine whether PICC-related thrombosis is influenced by ABO blood group. We identified patients admitted to Hurley Medical Center between March 2012 and March 2016 who had PICC placed during their admission, had their ABO blood group identified in their medical record, and had upper extremity venous Doppler ultrasound performed on the same side of PICC...
January 1, 2018: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/29682369/intrahepatic-cholangiocarcinoma-masquerading-as-acute-fatty-liver-of-pregnancy-a-case-report-and-review-of-the-literature
#13
Ayman Qasrawi, Omar Abughanimeh, Mouhanna Abu Ghanimeh, Simran Arora-Elder, Osama Yousef, Tarek Tamimi
Cholangiocarcinoma (CCA) is an uncommon cancer and accounts only for 3% of all gastrointestinal malignancies. In this report, we present a case of an intrahepatic cholangiocarcinoma masquerading as acute fatty liver of pregnancy (AFLP). A 38-year-old female who is 36-week pregnant presented with a 1-week history of headache, nausea, vomiting, and right upper abdominal pain, along with hepatomegaly. Laboratory investigations were remarkable for mild leukocytosis, hyperbilirubinemia, proteinuria, and elevated transaminases and prothrombin time...
2018: Case Reports in Hepatology
https://www.readbyqxmd.com/read/29676634/impact-of-seasonal-winter-air-pollution-on-health-across-the-lifespan-in-mongolia-and-some-putative-solutions
#14
David Warburton, Nicole Warburton, Clarence Wigfall, Ochir Chimedsuren, Delgerzul Lodoisamba, Sereeter Lodoysamba, Badarch Jargalsaikhan
Environmental pollution of the air, water, and soil comprise an increasingly urgent challenge to global health, well-being, and productivity. The impact of environmental pollution arguably has its greatest impact across the lifespan on children, women of childbearing age, and pregnant women and their unborn children, not only because of their vulnerability during development, but also because of their subsequent longevity. Ulaanbaatar, Mongolia, is a highly instructive, perhaps extreme, example of what happens with recent, rapid urbanization...
April 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29674762/current-multidisciplinary-approach-to-fertility-preservation-for-breast-cancer-patients
#15
Yuko Takahashi, Tadahiko Shien, Ai Sakamoto, Yuko Tsuyumu, Ryo Yoshioka, Maya Uno, Minami Hatono, Mariko Kochi, Kengo Kawada, Takahiro Tsukioki, Takayuki Iwamoto, Hirokuni Ikeda, Naruto Taira, Junji Matsuoka, Mikiya Nakatsuka, Hiroyoshi Doihara
Adverse effects on fertility are a significant problem for premenopausal breast cancer patients. Since April 2009, we have been referring young patients for fertility counseling provided by a multidisciplinary team. Here we evaluated the efficacy and safety of our current fertility preservation approach. We retrospectively analyzed the cases of 277 patients < 45 years old at diagnosis, which was made between 2009 and 2016. Seventy-two (26%) patients received fertility counseling. Seventeen (6%) of the 277 patients decided to preserve their fertility before starting adjuvant systemic therapy...
April 2018: Acta Medica Okayama
https://www.readbyqxmd.com/read/29666189/single-cell-rna-seq-reveals-cell-heterogeneity-and-hierarchy-within-mouse-mammary-epithelia
#16
Heng Sun, Zhengqiang Miao, Xin Zhang, Un In Chan, Sek Man Su, Sen Guo, Chris Koon Ho Wong, Xiaoling Xu, Chu-Xia Deng
The mammary gland is very intricately and well organized into distinct tissues, including epithelia, endothelia, adipocytes, and stromal and immune cells. Many mammary gland diseases, such as breast cancer arise from abnormalities in the mammary epithelium, which is mainly composed of two distinct lineages, the basal and luminal cells. Because of the limitation of traditional transcriptome analysis of bulk mammary cells, the hierarchy and heterogeneity of mammary cells within these two lineages remain unclear...
April 17, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29625257/5-year-overall-survival-after-early-breast-cancer-diagnosed-during-pregnancy-a-retrospective-case-control-multicentre-french-study
#17
A Ploquin, B Pistilli, E Tresch, J S Frenel, F Lerebours, A Lesur, C Loustalot, T Bachelot, M Provansal, J M Ferrero, F Coussy, M Debled, P Kerbrat, A Vinceneux, D Allouache, F Morvan, F Dalenc, S Guiu, R Rouzier, L Vanlemmens
BACKGROUND: Breast cancer diagnosed during pregnancy (BCP) is rare, but the prevalence is expected to rise. Long-term follow-up data regarding this clinically challenging condition are scarce. The main objective of this multicentre case-control French study was to compare the survival between pregnant patients and matched controls. METHODS: Patients from 27 centres diagnosed between 2000 and 2009 with histologically proven invasive breast cancer occurring during pregnancy were retrospectively included...
April 3, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29623667/a-review-of-the-opioid-epidemic-what-do-we-do-about-it
#18
REVIEW
Edward A Shipton, Elspeth E Shipton, Ashleigh J Shipton
The opioid epidemic, with its noticeable increase in opioid prescriptions and related misuse, abuse and resultant deaths in the previous 12 years, is a particularly North American phenomenon. Europe, and particularly low- and middle-income countries, appear to be less influenced by this problem. There is undisputable value in using opioids not only in the treatment of acute pain, but in cancer pain as well. However, opioids are progressively being prescribed more and more for chronic non-cancer pain, despite inadequate data on their efficacy...
April 6, 2018: Pain and Therapy
https://www.readbyqxmd.com/read/29618241/lung-adenocarcinoma-during-pregnancy-clinical-case-and-literature-review
#19
C Bellido, P Barbero, L Forcén, M Alonso, M Blanco, A Galindo
Lung cancer during pregnancy is a very rare disease with less than 70 cases published to date. Information about specific lung cancer as adenocarcinoma is even more limited. Genetic techniques can detect oncogene mutations which seem to be more frequent among cases of lung cancer in pregnant women and could determine both the treatment and prognosis. We present a recent case seen at our hospital and a literature review.
April 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29574609/outcome-of-immature-oocytes-collection-of-119-cancer-patients-during-ovarian-tissue-harvesting-for-fertility-preservation
#20
Alon Kedem, Gil M Yerushalmi, Masha Brengauz, Hila Raanani, Raoul Orvieto, Ariel Hourvitz, Dror Meirow
PURPOSE: Few clinical options for fertility preservation are available to females with cancer, and data about clinical outcomes is limited. Potential supplementary approaches to fertility preservation include retrieval of immature oocytes followed by in vitro maturation (IVM) and storage. The aim of this study was to evaluate post-thawing outcomes of immature oocytes collected both by transvaginal aspiration and from excised ovarian tissue. METHODS: We conducted a retrospective cohort study of patients treated in a single tertiary center...
March 24, 2018: Journal of Assisted Reproduction and Genetics
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