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https://www.readbyqxmd.com/read/28528350/prevalence-and-impact-of-severe-fatigue-in-adolescent-and-young-adult-cancer-patients-in-comparison-with-population-based-controls
#1
Hanneke Poort, Suzanne E J Kaal, Hans Knoop, Rosemarie Jansen, Judith B Prins, Eveliene Manten-Horst, Petra Servaes, Olga Husson, Winette T A van der Graaf
PURPOSE: The current study determined the prevalence of severe fatigue in adolescent and young adult (AYA) cancer patients (aged 18-35 years at diagnosis) consulting a multidisciplinary AYA team in comparison with gender- and age-matched population-based controls. In addition, impact of severe fatigue on quality of life and correlates of fatigue severity were examined. METHODS: AYAs with cancer (n = 83) completed questionnaires including the Checklist Individual Strength (CIS-fatigue), Quality of Life (QoL)-Cancer Survivor, Hospital Anxiety and Depression Scale (reflecting psychological distress), and the Cancer Worry Scale (reflecting fear of cancer recurrence or progression)...
May 20, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28528292/cancer-incidence-in-the-western-australian-mining-industry-1996-2013
#2
Nita Sodhi-Berry, Alison Reid, Lin Fritschi, Aw Bill Musk, Roel Vermeulen, Nicholas de Klerk, Susan Peters
BACKGROUND: Miners are frequently exposed to established and potential carcinogens. We aimed to assess cancer incidence in miners relative to the general population and identify high-risk subgroups. METHODS: Incident cancers in Western Australian miners (n=153,922; 86% male) during 1996-2013 were identified. Indirectly standardised incidence ratios (SIRs) were calculated and mixed-effects Poisson models were used to calculate Incidence Rate Ratios (IRRs) to identify high-risk within-cohort subgroups...
May 18, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28528207/interventions-to-increase-male-attendance-and-testing-for-sexually-transmitted-infections-at-publicly-funded-family-planning-clinics
#3
David Fine, Lee Warner, Sarah Salomon, David M Johnson
PURPOSE: We assessed the impact of staff, clinic, and community interventions on male and female family planning client visit volume and sexually transmitted infection testing at a multisite community-based health care agency. METHODS: Staff training, clinic environmental changes, in-reach/outreach, and efficiency assessments were implemented in two Family Health Center (San Diego, CA) family planning clinics during 2010-2012; five Family Health Center family planning programs were identified as comparison clinics...
May 17, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28527372/dreams-deferred-contextualizing-the-health-and-psychosocial-needs-of-undocumented-asian-and-pacific-islander-young-adults-in-northern-california
#4
May Sudhinaraset, Irving Ling, Tu My To, Jason Melo, Thu Quach
There are currently 1.5 million undocumented Asians and Pacific Islanders (APIs) in the US. Undocumented API young adults, in particular, come of age in a challenging political and social climate, but little is known about their health outcomes. To our knowledge, this is the first study to assess the psychosocial needs and health status of API undocumented young adults. Guided by social capital theory, this qualitative study describes the social context of API undocumented young adults (ages 18-31), including community and government perceptions, and how social relationships influence health...
May 10, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28527212/apolipoprotein-e4-gender-body-mass-index-inflammation-insulin-resistance-and-air-pollution-interactions-recipe-for-alzheimer-s-disease-development-in-mexico-city-young-females
#5
Lilian Calderón-Garcidueñas, Suzanne M de la Monte
Given the epidemiological trends of increasing Alzheimer's disease (AD) and growing evidence that exposure and lifestyle factors contribute to AD risk and pathogenesis, attention should be paid to variables such as air pollution, in order to reduce rates of cognitive decline and dementia. Exposure to fine particulate matter (PM2.5) and ozone (O3) above the US EPA standards is associated with AD risk. Mexico City children experienced pre- and postnatal high exposures to PM2.5, O3, combustion-derived iron-rich nanoparticles, metals, polycyclic aromatic hydrocarbons, and endotoxins...
May 17, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28527122/effects-of-cigarette-smoke-exposure-during-suckling-on-food-intake-fat-mass-hormones-and-biochemical-profile-of-young-and-adult-female-rats
#6
Patricia Cristina Lisboa, Patricia Novaes Soares, Thamara Cherem Peixoto, Janaine Cavalcanti Carvalho, Camila Calvino, Vanessa Silva Tavares Rodrigues, Dayse Nascimento Bernardino, Viviane Younes-Rapozo, Alex Christian Manhães, Elaine de Oliveira, Egberto Gaspar de Moura
PURPOSE: Children from smoking mothers have a higher risk of developing obesity and associated comorbidities later in life. Different experimental models have been used to assess the mechanisms involved with this increased risk. Using a rat model of neonatal nicotine exposure via implantation of osmotic minipumps in lactating dams, we have previously shown marked sexual dimorphisms regarding metabolic and endocrine outcomes in the adult progeny. Considering that more than four thousand substances are found in tobacco smoke besides nicotine, we then studied a rat model of neonatal tobacco smoke exposure: adult male offspring had hyperphagia, obesity, hyperglycemia, hypertriglyceridemia, secondary hyperthyroidism and lower adrenal hormones...
May 19, 2017: Endocrine
https://www.readbyqxmd.com/read/28526997/nafld-as-a-sexual-dimorphic-disease-role-of-gender-and-reproductive-status-in-the-development-and-progression-of-nonalcoholic-fatty-liver-disease-and-inherent-cardiovascular-risk
#7
REVIEW
Stefano Ballestri, Fabio Nascimbeni, Enrica Baldelli, Alessandra Marrazzo, Dante Romagnoli, Amedeo Lonardo
Nonalcoholic fatty liver disease (NAFLD) spans steatosis through nonalcoholic steatohepatis, cirrhosis, and hepatocellular carcinoma (HCC) associated with striking systemic features and excess cardiovascular and liver-related mortality. The pathogenesis of NAFLD is complex and multifactorial. Endocrine derangements are closely linked with dysmetabolic traits. For example, in animal and human studies, female sex is protected from dysmetabolism thanks to young individuals' ability to partition fatty acids towards ketone body production rather than very low density lipoprotein (VLDL)-triacylglycerol, and to sex-specific browning of white adipose tissue...
May 19, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28526372/the-impact-of-drinking-age-laws-on-perpetration-of-sexual-assault-crimes-in-canada-2009-2013
#8
Jodi M Gatley, Marcos Sanches, Claire Benny, Samantha Wells, Russell C Callaghan
PURPOSE: Sexual-assault crimes, primarily perpetrated by males against female victims, impose a substantial burden on societies worldwide, especially on youth. Given that approximately half of all sexual assaults involve alcohol consumption by the perpetrator or victim, it is reasonable to expect that minimum legal drinking age (MLDA) restrictions might have an effect on sexual-assault patterns. Canadian MLDA laws are 18 years in Quebec, Alberta, and Manitoba (MLDA-18), and 19 years in the rest of the country (MLDA-19)...
May 16, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28526331/prevalence-of-oral-human-papillomavirus-by-vaccination-status-among-young-adults-18-30years-old
#9
Jacqueline M Hirth, Mihyun Chang, Vicente A Resto
BACKGROUND: Although there is evidence that human papillomavirus (HPV) vaccination may protect against oral HPV infection, no current research has demonstrated this in the general population. METHODS: We used repeated cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) between 2009 and 2014. Participants 18-30years who indicated whether they had received the HPV vaccine and provided an adequate oral sample were included (N=3040)...
May 16, 2017: Vaccine
https://www.readbyqxmd.com/read/28525535/sexual-dimorphism-and-aging-differentially-regulate-adaptive-homeostasis
#10
Laura C D Pomatto, John Tower, Kelvin J A Davies
External and internal stimuli cause modifications to gene and biochemical pathways. In turn, demonstrating that biological systems continuously make short-term adaptations both to set-points, and to the range of "normal" capacity, due to mild conditional changes, or to subtoxic, nondamaging levels of chemical agents. This is termed as "Adaptive Homeostasis," defined with the following: "The transient expansion or contraction of the homeostatic range in response to exposure to sub-toxic, nondamaging, signaling molecules or events, or the removal or cessation of such molecules or events...
May 18, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28525442/prevalence-and-determinants-of-hypertension-and-high-normal-blood-pressure-among-young-adult-saudi-females-insights-into-preventive-strategies
#11
Maha A Al-Mohaissen, Qumasha Y Al-Obaid, Wafa A AlGhamdi, Haneen S Al-Alyani, Sheima M Dahman, Nora A Al-Wahhabi, Noura M Al-Awaji, Terry Lee
This study aimed to determine the prevalence of hypertension and high normal blood pressure and their risk factors among young adult Saudi females. A prospective cross-sectional study was conducted in a women's university. A questionnaire evaluated the subjects' demographic data and risk factors for hypertension and the blood pressure, height, and weight were recorded. In all, 4.1% of the participants were hypertensive and 6.2% had high normal blood pressure. Significant predictors of hypertension/high normal blood pressure were increased body mass index, increased heart rate, walking fewer days per week, and dietary factors...
July 2017: Family & Community Health
https://www.readbyqxmd.com/read/28525408/rebound-deformity-after-growth-modulation-in-patients-with-coronal-plane-angular-deformities-about-the-knee-who-gets-it-and-how-much
#12
Lise A Leveille, Ozan Razi, Charles E Johnston
BACKGROUND: With observed success and increased popularity of growth modulation techniques, there has been a trend toward use in progressively younger patients. Younger age at growth modulation increases the likelihood of complete deformity correction and need for implant removal before skeletal maturity introducing the risk of rebound deformity. The purpose of this study was to quantify magnitude and identify risk factors for rebound deformity after growth modulation. METHODS: We performed a retrospective review of all patients undergoing growth modulation with a tension band plate for coronal plane deformity about the knee with subsequent implant removal...
May 18, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28524541/-worried-about-relapse-family-members-experiences-and-perspectives-of-relapse-in-first-episode-psychosis
#13
Shalini Lal, Ashok Malla, Gina Marandola, Joanie Thériault, Phil Tibbo, Rahul Manchanda, Richard Williams, Ridha Joober, Nicola Banks
BACKGROUND: The purpose of this study was to gain an in-depth understanding on the subject of relapse from the perspectives of family members of young people receiving services for a first-episode psychosis (FEP). METHODS: A qualitative descriptive approach, using focus group methods, was used to elicit experiences, understandings, and knowledge of relapse in FEP. Family members were recruited from 4 specialized early intervention programmes for psychosis in Canada...
May 19, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28524366/contrasting-hcv-and-hiv-seroepidemiology-in-11-years-of-blood-donors-screening-in-brazil
#14
J E Levi, S M Lira, C B Bub, M B Polite, C C Terzian, J M Kutner
BACKGROUND: Blood donors are, in principle, healthy individuals who may be revealed as infectious for blood-borne agents by the laboratory screening process, depicting the asymptomatic burden of the disease. Therefore, monitoring hepatitis C virus (HCV)-infected donor and human immunodeficiency virus (HIV)-infected donor and associating to their demographical and behavioural characteristics may shed light on the dynamics and contemporary changes in these viruses' epidemiology. METHODS: Donors presenting repeatedly reactive HCV or HIV serology/nucleic acid testing (NAT) screening results were submitted to confirmatory testing...
May 19, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28523319/amyloidosis-a-rare-cause-of-refractory-heart-failure-in-a-young-female
#15
Irina Iuliana Costache, Claudia Florida Costea, Mihai Danciu, Victor Vlad Costan, Viviana Aursulesei, Gabriela FlorenŢa Dumitrescu, Mihaela Dana Turliuc, Anca Sava
Cardiac amyloidosis may occur in any type of systemic amyloidosis. The clinical picture is often characterized by restrictive cardiomyopathy. We report the case of a 41-year-old female patient admitted to the Department of Cardiology with clinical signs of right heart failure: congested jugular veins, hepatomegaly, peripheral edema, ascites associated with atrial fibrillation, low values of arterial blood pressure and oliguria. Echocardiographic findings were helpful for the diagnosis of cardiac amyloidosis: enlarged atrial cavities, normal size ventricles, thickened ventricular septum and posterior left ventricle wall with normal left ventricular ejection fraction, mitral and tricuspid regurgitation...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28523176/ct-localization-for-a-patient-with-a-ground-glass-opacity-pulmonary-nodule-expecting-thoracoscopy-a-mixture-of-lipiodol-and-india-ink
#16
Kyung Soo Kim, Kyongmin Sarah Beck, Kyo Young Lee, Seok Whan Moon
Small and deeply seated pure ground-glass opacity (GGO) pulmonary nodules (PNs) are not discernible during video-assisted thoracoscopic surgery (VATS). Moreover, pathologists have difficulty in detecting these nodules due to insufficient localization. We percutaneously injected a mixture of lipiodol and India ink during preoperative CT-guided localization in a 52-year-old female patient presenting with a pure GGO PN. A black-pigmented tattoo lesion was clearly identified, and thoracoscopic wedge resection was performed without difficulty...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28523092/management-of-a-life-threatening-bleeding-following-extraction-of-deciduous-second-molar-related-to-a-capillary-haemangioma
#17
REVIEW
Amr Amin Ghanem, Yasser Nabil El Hadidi
Various forms of vascular lesion affect the head and neck region. The head and neck vascular lesions are classified into neoplasms and malformations. Neoplasm presents either as hemangioma or lymphangioma; neoplasm usually presents in young age compared with vascular malformation. A 9-year-old female patient presented to the outpatient clinic referred from the department of pedodontics after extraction of a right mandibular second deciduous molar. Extraction was done by dental GP in outpatient clinic. Massive bleeding followed the extraction...
June 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/28523045/frequency-of-nutritional-anemia-among-female-medical-students-of-faisalabad
#18
Shireen Jawed, Sundus Tariq, Saba Tariq, Anwar Kamal
BACKGROUND AND OBJECTIVE: Anemia is a common health problem worldwide. This problem is most commonly faced by 18 to 25 years of females. Medical students especially female hostelites poses high risk of anemia because of their poor eating habits, breakfast skipping, long schedule in college, burden of medical studies, clinical postings, and extra-curricular activities. Therefore the current study was designed to determine the hemoglobin status in young female medical students. We also elucidate its association with BMI...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28522415/behavioural-adaptation-of-the-rice-leaf-folder-cnaphalocrocis-medinalis-to-short-term-heat-stress
#19
Muhammad Adnan Bodlah, Ling-Ling Gu, Ye Tan, Xiang-Dong Liu
Under ongoing climate warming, both the degree and number of high-temperature events in summer may increase, and behavioural adaptation is an important ecological strategy employed by insects to cope with such events. The rice leaf folder, Cnaphalocrocis medinalis Güenée, is a serious insect pest of rice fields in summer. Population outbreaks have become more frequent in the last ten years. In addition to adult migration, rice leaf folders are thought to have other thermal adaptations. Therefore, the behaviours of larval and adult rice leaf folders, such as leaf folding (making shelter) and habitat selection for pupae and eggs, were observed on rice plants under heat stress...
May 15, 2017: Journal of Insect Physiology
https://www.readbyqxmd.com/read/28522256/sporadic-early-onset-diffuse-gastric-cancers-have-high-frequency-of-somatic-cdh1-alterations-but-low-frequency-of-somatic-rhoa-mutations-compared-with-late-onset-cancers
#20
Soo Young Cho, Jun Won Park, Yang Liu, Young Soo Park, Ju Hee Kim, Hanna Yang, Hyejin Um, Woo Ri Ko, Byung Il Lee, Sun Young Kwon, Seung Wan Ryu, Chae Hwa Kwon, Do Youn Park, Jae-Hyuk Lee, Sang Il Lee, Kyu Sang Song, Hoon Hur, Sang-Uk Han, Heekyung Chang, Su-Jin Kim, Byung-Sik Kim, Jeong-Hwan Yook, Moon-Won Yoo, Beom-Su Kim, In-Seob Lee, Myeong-Cherl Kook, Nina Thiessen, An He, Chip Stewart, Andrew Dunford, Jaegil Kim, Juliann Shih, Gordon Saksena, Andrew D Cherniack, Steven Schumacher, Amaro-Taylor Weiner, Mara Rosenberg, Gad Getz, Eun Gyeong Yang, Min Hee Ryu, Adam J Bass, Hark Kyun Kim
BACKGROUND & AIMS: Early-onset gastric cancer, which develops in younger patients than most gastric cancers, is usually detected at advanced stages, has diffuse histologic features, and occurs more frequently in women. We investigated somatic genomic alterations associated with the unique characteristics of sporadic diffuse gastric cancers (DGCs) from younger patients. METHODS: We conducted whole exome and RNA sequence analyses of 80 resected DGC samples from patients 45 years old or younger in Korea...
May 15, 2017: Gastroenterology
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