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https://www.readbyqxmd.com/read/28609794/-destruction-of-microsurgical-devices-by-sterilisation
#1
Raphaela Berto, Jürgen Strutz
Hospital facilities issue numerous risk announcements on corrosion, deformation or premature wearout of medical devices every year. As there is yet little data on the impact of reprocessing on the quality and durability of microsurgical instruments, this paper aims at evaluating the effects of the reprocessing on microsurgical instruments. Material and Methods 22 brand new microsurgical instruments for stapes surgery were being reprocessed 30 times without being used for surgery or other purposes in the interim time...
June 13, 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28607022/pharmacokinetics-of-pyrazinamide-optimising-dosing-regimens-for-drug-sensitive-and-resistant-tuberculosis
#2
Maxwell T Chirehwa, Helen McIlleron, Roxana Rustomjee, Thuli Mthiyane, Philip Onyebujoh, Peter Smith, Paolo Denti
Pyrazinamide is used in the treatment of tuberculosis(TB) because its sterilising effect against tubercle bacilli allows treatment shortening. It is part of standard treatment for drug-susceptible and drug-resistant TB, and it is being considered as a companion drug in novel regimens. The aim of this analysis was to characterize factors contributing to the variability in exposure and to evaluate drug exposures using alternative doses, thus providing evidence to support revised dosing recommendations for drug-susceptible and multi-drug resistant tuberculosis(MDR-TB)...
June 12, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28601505/heat-and-chemical-treatments-in-adult-cyprinus-carpio-pisces-cypriniformes-rapidly-produce-sterile-gonads
#3
Sullip Kumar Majhi, Avinash Rambhau Rasal, Basdeo Kushwaha, Sudhir Raizada
Several options have been proposed for eradication of germ cells (GCs) in mammals such as treatment with cytotoxic drugs, irradiation, cold ischemia and hyperthermic treatment. Some of these methods have been also tried in fish but conditions for complete sterilisation of gonads have not been established. Here, we report the production of sterile adult common carp Cyprinus carpio in 10 weeks by the heat and chemical treatments. The cytotoxic drug busulfan (40mg/kg) was intraperitoneally injected into the animals at 2-week intervals (5 doses in total), and they were maintained in water at 38°C between Weeks 1 and 10...
June 3, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28600937/consideration-of-rainwater-quality-parameters-for-drinking-purposes-a-case-study-in-rural-vietnam
#4
Minju Lee, Mikyeong Kim, Yonghwan Kim, Mooyoung Han
Rainwater, which is used for drinking purposes near Hanoi, Vietnam, was analysed for water quality based on 1.5 years of monitoring data. In total, 23 samples were collected from different points within two rainwater harvesting systems (RWHSs). Most parameters met the standard except micro-organisms. Coliform and Escherichia coli (E. coli) were detected when the rainwater was not treated with ultraviolet (UV) light; however, analysis of rainwater after UV sterilisation showed no trace of micro-organisms. The RWHSs appear to provide drinking water of relatively good quality compared with surface water and groundwater...
June 7, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28597930/infection-control-guidelines-for-optometrists-2016
#5
Ka-Yee Lian, Genevieve Napper, Fiona J Stapleton, Patricia M Kiely
BACKGROUND: This paper provides an updated version of the paper: Infection control guidelines for optometrists 2007. METHODS: Information from peer-reviewed journal articles, guidelines from professional societies, and government health department and other websites and instructions from equipment manufacturers were considered in determining infection risk factors in optometric practice. They were used to revise the recommendations on disinfection, sterilisation and reprocessing procedures for instrumentation and other equipment used in optometric practice as well as personal infection control measures to be undertaken by staff...
June 9, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28575446/transgender-sterilisation-requirements-in-europe
#6
Peter Dunne
The possibility of individuals procreating post-transition has long stalked debates on transgender rights. In 1972, Sweden became the first European jurisdiction to formally acknowledge preferred gender. Under the original Swedish law, applicants for gender recognition were explicitly required to prove an incapacity to reproduce-either through natural infertility or through a positive act of sterilisation. Across the Council of Europe, 20 countries continue to enforce a sterilisation requirement. When considering reforms to their current gender recognition rules as recently as 2015, the Polish executive and the Finnish legislature both rejected proposals to remove mandatory infertility provisions...
June 1, 2017: Medical Law Review
https://www.readbyqxmd.com/read/28567620/endophytic-fungal-assemblage-in-achyranthes-aspera-linn-revealed-by-internal-transcribed-spacer-region-of-nuclear-ribosomal-rna-genes
#7
Reshma John, Linu Mathew
Only scanty reports are available on endophytic fungal associations in Achyranthes aspera Linn. Hence in this study a total of 504 isolates belonging to ten different species of fungi were isolated from asymptomatic, surface sterilised segments of leaf, stem and root of A. aspera collected from different locations of Kerala, India. Among the isolates ascomycetes were most prevalent. Colonisation rate of fungal endophytes was high in leaf tissue (95%) followed by stem (77.75%) and root segments (33.33%). The most frequent and dominant coloniser of the host plant were Colletotrichum sp...
June 2017: 3 Biotech
https://www.readbyqxmd.com/read/28560504/development-of-cordycepin-formulations-for-preclinical-and-clinical-studies
#8
Jong Bong Lee, Cecilia Adrower, Chaolong Qin, Peter M Fischer, Cornelia H de Moor, Pavel Gershkovich
There is extensive literature on in vivo studies with cordycepin, but these studies were generally conducted without validation of the various formulations, especially in terms of the solubility of cordycepin in the dosing vehicles used. Cordycepin is a promising drug candidate in multiple therapeutic areas, and there is a growing interest in studies aimed at assessing the pharmacological activity of this compound in relevant animal disease models. It is likely that many reported in vivo studies used formulations in which cordycepin was incompletely soluble...
May 30, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28559254/human-bile-reduces-antimicrobial-activity-of-selected-antibiotics-against-enterococcus-faecalis-and-escherichia-coli-in-vitro
#9
Beatrix Wulkersdorfer, David Jaros, Sabine Eberl, Stefan Poschner, Walter Jäger, Enrico Cosentini, Markus Zeitlinger, Richard Schwameis
It has been known from previous studies that body fluids, such as cerebrospinal fluid, lung surfactant and urine, have a strong impact on the bacterial killing of many anti-infective agents. However, the influence of human bile on the antimicrobial activity of antibiotics is widely unknown. Human bile was obtained and pooled from 11 patients undergoing cholecystectomy. After sterilisation of the bile fluid by gamma irradiation its effect on bacterial killing was investigated for linezolid (LZD) and tigecycline (TGC) against Enterococcus faecalis ATCC 29212...
May 30, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28549287/unconventional-energy-resources-in-a-crowded-subsurface-reducing-uncertainty-and-developing-a-separation-zone-concept-for-resource-estimation-and-deep-3d-subsurface-planning-using-legacy-mining-data
#10
Alison A Monaghan
Over significant areas of the UK and western Europe, anthropogenic alteration of the subsurface by mining of coal has occurred beneath highly populated areas which are now considering a multiplicity of 'low carbon' unconventional energy resources including shale gas and oil, coal bed methane, geothermal energy and energy storage. To enable decision making on the 3D planning, licensing and extraction of these resources requires reduced uncertainty around complex geology and hydrogeological and geomechanical processes...
May 23, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28545584/can-community-health-workers-play-a-greater-role-in-increasing-access-to-medical-abortion-services-a-qualitative-study
#11
Pallavi Gupta, Sharad D Iyengar, Bela Ganatra, Heidi Bart Johnston, Kirti Iyengar
BACKGROUND: Despite being legally available in India since 1971, barriers to safe and legal abortion remain, and unsafe and/or illegal abortion continues to be a problem. Community health workers have been involved in improving access to health information and care for maternal and child health in resource poor settings, but their role in facilitating accurate information about and access to safe abortion has been relatively unexplored. A qualitative study was conducted in Rajasthan, India to study acceptability, perspectives and preferences of women and community health workers, regarding the involvement of community health workers in medical abortion referrals...
May 25, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28534057/the-effect-of-thawing-protocols-on-follicle-conservation-in-human-ovarian-tissue-cryopreservation
#12
T Morewood, N Getreu, B Fuller, J Morris, P Hardiman
BACKGROUND: Ovarian tissue cryopreservation has the potential to improve fertility preservation for a growing number of patients undergoing sterilising therapy, particularly where oocyte or embryo cryopreservation is not suitable. However, its success is limited by significant follicular apoptosis upon thawing, and there is wide variation in thawing protocols used with little evidence of efficacy. OBJECTIVE: To determine the best warming rates to maintain tissue viability...
March 2017: Cryo Letters
https://www.readbyqxmd.com/read/28528368/preparation-of-allogeneic-bone-for-alveolar-ridge-augmentation
#13
Kornel Krasny, Artur Kamiński, Marta Krasny, Tomasz Czech, Andrzej Wojtowicz
Implant treatment is safe and predictable with sufficient amount and quality of bone tissue. In case of severely reduced bone tissue after a tooth was lost, augmentation of such tissue is necessary before implant embedment. Retrospective evaluation covered 380 alveolar ridge reconstructions. The study material consisted of human grafts prepared by the Department of Transplantology and Central Tissue Bank, Medical University of Warsaw. Presentation of laboratory procedures in the context of physical parameters of frozen, radiation sterilised, allogeneic corticocancellous material was presented...
May 20, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/28527614/n-o-344-salpingectomie-opportuniste-et-autres-m%C3%A3-thodes-pour-r%C3%A3-duire-le-risque-de-cancer-de-l-ovaire-de-la-trompe-de-fallope-et-du-p%C3%A3-ritoine-dans-la-population-g%C3%A3-n%C3%A3-rale
#14
Shannon Salvador, Stephanie Scott, Julie Ann Francis, Anita Agrawal, Christopher Giede
OBJECTIF: La présente directive clinique examine les avantages potentiels de la salpingectomie opportuniste pour prévenir le développement du cancer séreux de grade élevé de l'ovaire, de la trompe de Fallope et du péritoine à la lumière de données probantes actuelles selon lesquelles ce type de cancer prendrait naissance dans la trompe de Fallope. UTILISATEURS CIBLES: Gynécologues, obstétriciens, médecins de famille, infirmières autorisées, infirmières praticiennes, résidents et fournisseurs de soins de santé...
June 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28464415/safety-and-effectiveness-of-female-tubal-sterilisation-by-hysteroscopy-laparoscopy-or-laparotomy-a-register-based-study
#15
E Jokinen, A Heino, T Karipohja, M Gissler, R Hurskainen
OBJECTIVE: To determine the safety and effectiveness of female sterilisation in the Finnish population. DESIGN: A national register-based study using record linkage. SETTING: National data from Finland. SAMPLE: A total of 16 272 female sterilisations performed in 2009-2014. METHODS: The Register of Sterilisations was linked with the Hospital Discharge Register, Termination of Pregnancy Register, and the Medical Birth Register in order to investigate the occurrence of re-sterilisations, other surgical operations, and unwanted pregnancies after sterilisation, per method...
May 2, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28449861/the-effects-of-irradiation-dose-and-storage-time-following-treatment-on-the-viscoelastic-properties-of-decellularised-porcine-super-flexor-tendon
#16
Anthony Herbert, Jennifer H Edwards, Gemma L Jones, Eileen Ingham, John Fisher
Decellularised porcine super flexor tendon (pSFT) offers a promising solution to the replacement of damaged anterior cruciate ligament. It is desirable to package and terminally sterilise the acellular grafts to eliminate any possible harmful pathogens. However, irradiation techniques can damage the collagen structure and consequently reduce the mechanical properties. The aims of this study were to investigate the effects of irradiation sterilisation of varying dosages on the viscoelastic properties of the decellularised pSFT...
April 19, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28442552/the-role-of-anticipated-decision-regret-and-the-patient-s-best-interest-in-sterilisation-and-medically-assisted-reproduction
#17
Heidi Mertes
There is a clear discrepancy in the way those who request medical assistance in pursuit of their reproductive choices are treated. On the one hand, women who request a sterilisation are urged to consider possible future regrets and are sometimes refused treatment in anticipation of such regrets. This is despite the fact that for all age ranges, the majority of women undergoing a sterilisation do not regret the decision. Moreover, women who are voluntarily childless are likely to have a happier and more gratifying life than parents...
May 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28431486/evaluating-the-operational-risks-of-biomedical-waste-using-failure-mode-and-effects-analysis
#18
Ying-Chu Chen, Pei-Yi Tsai
The potential problems and risks of biomedical waste generation have become increasingly apparent in recent years. This study applied a failure mode and effects analysis to evaluate the operational problems and risks of biomedical waste. The microbiological contamination of biomedical waste seldom receives the attention of researchers. In this study, the biomedical waste lifecycle was divided into seven processes: Production, classification, packaging, sterilisation, weighing, storage, and transportation. Twenty main failure modes were identified in these phases and risks were assessed based on their risk priority numbers...
April 1, 2017: Waste Management & Research
https://www.readbyqxmd.com/read/28388252/how-reliable-are-health-registers-registration-of-induced-abortions-and-sterilizations-in-finland
#19
Anna Heino, Maarit Niinimäki, Maarit Mentula, Mika Gissler
Finland's population-based health registers are widely used in health-monitoring and research. We assessed the quality of the Finnish Register on Induced Abortions and Sterilisations and compared it to the Hospital Discharge Register. Ten hospitals out of 67 public hospitals performing induced abortions and sterilizations and three randomly selected months in 2011 were included. This data was compared to the data in the Register on Induced Abortions and Sterilisations. The sample presented 43.1% of all induced abortions and sterilizations during the study months...
April 7, 2017: Informatics for Health & Social Care
https://www.readbyqxmd.com/read/28366279/chemical-sterilisation-of-animals-a-review-of-the-use-of-zinc-and-cacl2-based-solutions-in-male-and-female-animals-and-factors-likely-to-improve-responses-to-treatment
#20
REVIEW
John Cavalieri
Chemical sterilisation can be used as an alternative to surgical castration in some circumstances. This review focuses on responses to treatment with zinc- or CaCl2-based chemosterilants, factors that have affected treatments and their potential use to sterilise female cattle. Successful treatment with a low incidence of adverse side effects in male animals has occurred with the use of zinc gluconate (ZG), neutralised in arginine and a 20% solution of CaCl2 in ethanol. Injection technique plays an important role in success...
March 18, 2017: Animal Reproduction Science
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