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Emmanouil Brilakis

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https://www.readbyqxmd.com/read/27887799/procedural-and-longer-term-outcomes-of-wire-versus-device-based-antegrade-dissection-and-re-entry-techniques-for-the-percutaneous-revascularization-of-coronary-chronic-total-occlusions
#1
Lorenzo Azzalini, Rustem Dautov, Emmanouil S Brilakis, Soledad Ojeda, Susanna Benincasa, Barbara Bellini, Aris Karatasakis, Jorge Chavarría, Bavana V Rangan, Manuel Pan, Mauro Carlino, Antonio Colombo, Stéphane Rinfret
BACKGROUND: There are few data regarding the procedural and follow-up outcomes of different antegrade dissection/re-entry (ADR) techniques for chronic total occlusion (CTO) percutaneous coronary intervention (PCI). METHODS: We compiled a multicenter registry of consecutive patients undergoing ADR-based CTO PCI at four high-volume specialized institutions. Patients were divided according to the specific ADR technique used: subintimal tracking and re-entry (STAR), limited antegrade subintimal tracking (LAST), or device-based with the CrossBoss/Stingray system (Boston Scientific, Marlborough, MA)...
November 16, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27887687/comparison-of-lower-extremity-endovascular-intervention-outcomes-in-women-versus-men
#2
Haekyung Jeon-Slaughter, Shirling Tsai, Preeti Kamath, Nicolas W Shammas, Emmanouil S Brilakis, Subhash Banerjee
This study examined a gender difference in 12-month patient outcomes after endovascular intervention for symptomatic peripheral artery disease (PAD) utilizing propensity score-matched Excellence in Peripheral Artery Disease registry data. Mortality and repeat intervention outcomes after endovascular treatment in women compared with men in the existing literature are inconsistent and confounded by other risk factors. The study included 1,084 patients who underwent 1,702 endovascular procedures, at 8 non-Veterans Administration hospitals from January 2005 to October 2015...
November 1, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27886457/serenity-courage-and-wisdom-the-keys-to-successful-coronary-calcification-treatment
#3
EDITORIAL
Barbara Anna Danek, Emmanouil S Brilakis
No abstract text is available yet for this article.
November 15, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27860111/coronary-artery-spatial-distribution-of-chronic-total-occlusions-insights-from-a-large-us-registry
#4
Santiago Garcia, M Chadi Alraies, Aris Karatasakis, Demetris Yannopoulos, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, Mitul P Patel, John Bahadorani, Judit Karacsonyi, Pratik Kalsaria, Barbara Danek, Subhash Banerjee, Emmanouil S Brilakis
OBJECTIVE: To assess the spatial distribution of chronic total occlusions (CTOs) within the coronary arteries and describe procedural strategies and outcomes during CTO percutaneous coronary intervention (PCI). BACKGROUND: Acute occlusions due to plaque rupture tend to cluster within the proximal third of the coronary artery. METHODS: We examined the clinical and procedural characteristics of 1,348 patients according to lesion location within the coronary tree...
November 10, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27832850/comparative-assessment-of-procedure-cost-and-outcomes-between-guidewire-and-crossing-device-strategies-to-cross-peripheral-artery-chronic-total-occlusions
#5
Subhash Banerjee, Haekyung Jeon-Slaughter, Shirling Tsai, Atif Mohammad, Mazin Foteh, Mazen Abu-Fadel, Osvaldo S Gigliotti, Ian Cawich, Gerardo Rodriguez, Dharam Kumbhani, Tayo Addo, Michael Luna, Tony S Das, Anand Prasad, Ehrin J Armstrong, Nicolas W Shammas, Emmanouil S Brilakis
OBJECTIVES: The aim of this study was to assess actual procedural costs and outcomes comparing wire-catheter and dedicated chronic total occlusion (CTO) device strategies to cross peripheral artery CTOs. BACKGROUND: Peripheral artery CTO interventions are frequently performed, but there are limited data on actual procedural costs and outcomes comparing wire-catheter and dedicated CTO devices. METHODS: The XLPAD (Excellence in Peripheral Artery Disease Intervention) registry (NCT01904851) was accessed to retrospectively compare cost and 30-day and 12-month outcomes of wire-catheter and crossing device strategies for treatment of infrainguinal peripheral artery CTO...
November 14, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27788852/in-the-country-of-the-blind-the-one-eyed-man%C3%A2-is-king
#6
EDITORIAL
David R Holmes, Josep Rodes-Cabau, Emmanouil S Brilakis
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27747074/scoring-systems-for-chronic-total-occlusion-percutaneous-coronary-intervention-if-you-fail-to-prepare-you-are-preparing-to-fail
#7
COMMENT
Aris Karatasakis, Barbara Anna Danek, Emmanouil S Brilakis
No abstract text is available yet for this article.
September 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27729332/development-and-validation-of-a-scoring-system-for-predicting-periprocedural-complications-during-percutaneous-coronary-interventions-of-chronic-total-occlusions-the-prospective-global-registry-for-the-study-of-chronic-total-occlusion-intervention-progress
#8
Barbara Anna Danek, Aris Karatasakis, Dimitri Karmpaliotis, Khaldoon Alaswad, Robert W Yeh, Farouc A Jaffer, Mitul P Patel, Ehtisham Mahmud, William L Lombardi, Michael R Wyman, J Aaron Grantham, Anthony Doing, David E Kandzari, Nicholas J Lembo, Santiago Garcia, Catalin Toma, Jeffrey W Moses, Ajay J Kirtane, Manish A Parikh, Ziad A Ali, Judit Karacsonyi, Bavana V Rangan, Craig A Thompson, Subhash Banerjee, Emmanouil S Brilakis
BACKGROUND: High success rates are achievable for chronic total occlusion (CTO) percutaneous coronary intervention (PCI) using the hybrid approach, but periprocedural complications remain of concern. Although scores estimating success and efficiency in CTO PCI have been developed, there is currently no available score for estimation of the risk for periprocedural complications. We sought to develop a scoring tool for prediction of periprocedural complications during CTO PCI. METHODS AND RESULTS: We analyzed data from 1569 CTO PCIs in the Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS CTO) using a derivation and validation sampling ratio of 2:1...
October 11, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27726853/frequency-of-increase-in-cardiac-troponin-levels-after-peripheral-arterial-operations-carotid-endarterectomy-abdominal-aorta-procedure-distal-bypass-and-their-effect-on-medical-management
#9
Yader Sandoval, Marina Zakharova, Thomas S Rector, Emmanouil S Brilakis, Todd Drexel, Edward O McFalls, Santiago Garcia
The utility of measuring cardiac troponins (cTn) in asymptomatic patients during the perioperative period has been controversial. In the present substudy of the Cardiac Remote Ischemic Preconditioning Prior to Elective Vascular Surgery Trial (NCT01558596), we hypothesized that surveillance of myocardial injury with cTnI in the perioperative period would lead to initiation or intensification of medical therapies for coronary artery disease. Increases in cTnI ≥0.01 μg/l in the perioperative period were considered clinically significant...
September 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27712775/who-should-undergo-chronic%C3%A2-total%C3%A2-occlusion-percutaneous%C3%A2-coronary%C3%A2-intervention-the-exploration-continues
#10
Emmanouil S Brilakis, Shuaib M Abdullah, Subhash Banerjee
No abstract text is available yet for this article.
October 11, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27712732/utility-of-intravascular-ultrasound-in%C3%A2-percutaneous-revascularization-of%C3%A2-chronic%C3%A2-total-occlusions-an-overview
#11
Alfredo R Galassi, Satoru Sumitsuji, Marouane Boukhris, Emmanouil S Brilakis, Carlo Di Mario, Roberto Garbo, James C Spratt, Evald H Christiansen, Andrea Gagnor, Alexandre Avran, Georgios Sianos, Gerald S Werner
Intravascular ultrasound has been used for >20 years to guide percutaneous coronary intervention in different subsets of coronary lesions. During the last decade, the interest in percutaneous coronary intervention for chronic total occlusion (CTO) has increased dramatically, leading to high success rates. Failure of guidewire crossing is the most common reason for failed CTO attempts. Certain angiographic features, such as blunt proximal CTO cap, tortuosity, heavy calcification, and lack of visibility of path in the distal vessel, increase procedural difficulty...
October 10, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27705889/impact-of-proximal-cap-ambiguity-on-outcomes-of-chronic-total-occlusion-percutaneous-coronary-intervention-insights-from-a-multicenter-us-registry
#12
Aris Karatasakis, Barbara A Danek, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, Mitul P Patel, John N Bahadorani, R Michael Wyman, William L Lombardi, J Aaron Grantham, David E Kandzari, Nicholas J Lembo, Anthony H Doing, Jeffrey W Moses, Ajay J Kirtane, Santiago Garcia, Manish A Parikh, Ziad A Ali, Judit Karacsonyi, Sanjog Kalra, Bavana V Rangan, Pratik Kalsaria, Craig A Thompson, Subhash Banerjee, Emmanouil S Brilakis
OBJECTIVES: We sought to determine the impact of proximal cap ambiguity on procedural techniques and outcomes for coronary chronic total occlusion (CTO) percutaneous coronary intervention (PCI). METHODS: We examined the clinical and angiographic characteristics and outcomes of 1021 CTO-PCIs performed between 2012 and 2015 at 11 United States centers. RESULTS: Proximal cap ambiguity was present in 31% of target lesions and was associated with increased clinical and angiographic complexity (prior coronary artery bypass graft surgery: 43% vs 33%; P=...
October 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27688236/cardiac-remote-ischemic-preconditioning-prior-to-elective-vascular-surgery-cripes-a-prospective-randomized-sham-controlled-phase%C3%A2-ii-clinical-trial
#13
Santiago Garcia, Thomas S Rector, Marina Zakharova, Rebekah R Herrmann, Selcuk Adabag, Stefan Bertog, Yader Sandoval, Steve Santilli, Emmanouil S Brilakis, Edward O McFalls
BACKGROUND: Remote ischemic preconditioning (RIPC) has been shown to reduce infarct size in animal models. We hypothesized that RIPC before an elective vascular operation would reduce the incidence and amount of a postoperative rise of the cardiac troponin level. METHODS AND RESULTS: Cardiac Remote Ischemic Preconditioning Prior to Elective Vascular Surgery (CRIPES) was a prospective, randomized, sham-controlled phase 2 trial using RIPC before elective vascular procedures...
September 29, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27679596/utility-of-near-infrared-spectroscopy-for-detection-of-thin-cap-neoatherosclerosis
#14
Tomasz Roleder, Keyvan Karimi Galougahi, Chee Yang Chin, Navdeep K Bhatti, Emmanouil Brilakis, Tamim M Nazif, Ajay J Kirtane, Dimitri Karmpaliotis, Wojciech Wojakowski, Martin B Leon, Gary S Mintz, Akiko Maehara, Gregg W Stone, Ziad A Ali
AIMS: Near-infrared spectroscopy (NIRS) has been employed to assess the composition of the atherosclerotic plaques in native coronary arteries. However, little is known about the detection of neoatherosclerosis by NIRS in in-stent restenosis (ISR). The aim of the study was to assess the relationship between the distribution of lipid determined by NIRS and morphology of ISR on optical coherence tomography (OCT). METHODS AND RESULTS: We performed both NIRS and OCT in 39 drug-eluting stents with ISR...
September 27, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/27663227/real-time-fusion-of-coronary-ct-angiography-with-x-ray-fluoroscopy-during-chronic-total-occlusion-pci
#15
Brian B Ghoshhajra, Richard A P Takx, Luke L Stone, Erin E Girard, Emmanouil S Brilakis, William L Lombardi, Robert W Yeh, Farouc A Jaffer
OBJECTIVES: The purpose of this study was to demonstrate the feasibility of real-time fusion of coronary computed tomography angiography (CTA) centreline and arterial wall calcification with x-ray fluoroscopy during chronic total occlusion (CTO) percutaneous coronary intervention (PCI). METHODS: Patients undergoing CTO PCI were prospectively enrolled. Pre-procedural CT scans were integrated with conventional coronary fluoroscopy using prototype software. We enrolled 24 patients who underwent CTO PCI using the prototype CT fusion software, and 24 consecutive CTO PCI patients without CT guidance served as a control group...
September 23, 2016: European Radiology
https://www.readbyqxmd.com/read/27650935/prevalence-indications-and-management-of-balloon-uncrossable-chronic-total-occlusions-insights-from-a-contemporary-multicenter-us-registry
#16
Judit Karacsonyi, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, Mitul Patel, John Bahadorani, Anthony Doing, Ziad A Ali, Aris Karatasakis, Barbara A Danek, Bavana V Rangan, Aya J Alame, Subhash Banerjee, Emmanouil S Brilakis
BACKGROUND: Balloon uncrossable lesions can be challenging to treat, requiring specialized techniques and equipment. METHODS: We examined the prevalence, clinical and angiographic characteristics, management and procedural outcomes of balloon uncrossable lesions in a multicenter chronic total occlusion (CTO) percutaneous coronary intervention (PCI) registry. RESULTS: Between 2012 and 2016, 718 CTO PCIs (in which the occlusion was successfully crossed with a guidewire) were performed in 701 patients at 11 US centers...
September 21, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27611917/comparison-of-various-scores-for-predicting-success-of-chronic-total-occlusion-percutaneous-coronary-intervention
#17
Aris Karatasakis, Barbara A Danek, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, Mitul Patel, John N Bahadorani, William L Lombardi, R Michael Wyman, J Aaron Grantham, David E Kandzari, Nicholas J Lembo, Anthony H Doing, Catalin Toma, Jeffrey W Moses, Ajay J Kirtane, Manish A Parikh, Ziad A Ali, Santiago Garcia, Pratik Kalsaria, Judit Karacsonyi, Aya J Alame, Craig A Thompson, Subhash Banerjee, Emmanouil S Brilakis
BACKGROUND: Various scoring systems have been developed to predict the technical outcome and procedural efficiency of chronic total occlusion (CTO) percutaneous coronary intervention (PCI). METHODS: We examined the predictive capacity of 3 CTO PCI scores (Clinical and Lesion-related [CL], Multicenter CTO registry in Japan [J-CTO] and Prospective Global Registry for the Study of Chronic Total Occlusion Intervention [PROGRESS CTO] scores) in 664 CTO PCIs performed between 2012 and 2016 at 13 US centers...
August 23, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27543800/use-of-intravascular-imaging-during-chronic-total-occlusion-percutaneous-coronary-intervention-insights-from-a-contemporary-multicenter-registry
#18
Judit Karacsonyi, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, Mitul Patel, John Bahadorani, Aris Karatasakis, Barbara A Danek, Anthony Doing, J Aaron Grantham, Dimitri Karmpaliotis, Jeffrey W Moses, Ajay Kirtane, Manish Parikh, Ziad Ali, William L Lombardi, David E Kandzari, Nicholas Lembo, Santiago Garcia, Michael R Wyman, Aya Alame, Phuong-Khanh J Nguyen-Trong, Erica Resendes, Pratik Kalsaria, Bavana V Rangan, Imre Ungi, Craig A Thompson, Subhash Banerjee, Emmanouil S Brilakis
BACKGROUND: Intravascular imaging can facilitate chronic total occlusion (CTO) percutaneous coronary intervention. METHODS AND RESULTS: We examined the frequency of use and outcomes of intravascular imaging among 619 CTO percutaneous coronary interventions performed between 2012 and 2015 at 7 US centers. Mean age was 65.4±10 years and 85% of the patients were men. Intravascular imaging was used in 38%: intravascular ultrasound in 36%, optical coherence tomography in 3%, and both in 1...
2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27535486/saphenous-vein-graft-near-infrared-spectroscopy-imaging-insights-from-the-lipid-core-plaque-association-with-clinical-events-near-infrared-spectroscopy-oracle-nirs-registry
#19
Barbara A Danek, Aris Karatasakis, Aya J Alame, Phuong-Khanh J Nguyen-Trong, Judit Karacsonyi, Bavana Rangan, Michele Roesle, Amy Atwell, Erica Resendes, Jose Roberto Martinez-Parachini, Rahel Iwnetu, Pratik Kalsaria, Furqan Siddiqui, James E Muller, Subhash Banerjee, Emmanouil Brilakis
OBJECTIVES: We sought to examine near-infrared spectroscopy (NIRS) imaging findings of aortocoronary saphenous vein grafts (SVGs). BACKGROUND: SVGs are prone to develop atherosclerosis similar to native coronary arteries. They have received little study using NIRS. METHODS: We examined the clinical characteristics and imaging findings from 43 patients who underwent NIRS imaging of 45 SVGs at our institution between 2009 and 2016. RESULTS: The mean patient age was 67 ± 7 years and 98% were men, with high prevalence of diabetes mellitus (56%), hypertension (95%), and dyslipidemia (95%)...
August 18, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27491608/harnessing-the-potential-of-human%C3%A2-autologous-stem-cells-to-treat%C3%A2-refractory%C3%A2-angina
#20
EDITORIAL
Subhash Banerjee, Emmanouil S Brilakis
No abstract text is available yet for this article.
August 8, 2016: JACC. Cardiovascular Interventions
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