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Emmanouil Brilakis

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https://www.readbyqxmd.com/read/29440624/aminophylline-for-preventing-bradyarrhythmias-during-orbital-or-rotational-atherectomy-of-the-right-coronary-artery
#1
Michael Megaly, Yader Sandoval, Matthew P Lillyblad, Emmanouil S Brilakis
BACKGROUND: Coronary atherectomy, orbital or rotational, is frequently used for plaque modification in patients with heavily calcified lesions. Atherectomy can be associated with clinically significant bradyarrhythmias or transient atrioventricular block requiring temporary pacemaker insertion, mainly in lesions involving the right coronary artery or a dominant left circumflex artery. Bradyarrhythmias may be mediated by endogenous release of adenosine from red blood cell breakdown. Aminophylline, an adenosine antagonist, can prevent adenosine-mediated bradyarrhythmias...
February 15, 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29430781/editorial-retrograde-via-epicardial-collaterals-with-power-comes-responsibility
#2
EDITORIAL
Peter Tajti, Emmanouil S Brilakis
No abstract text is available yet for this article.
February 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29413236/randomized-comparison-of-a-crossboss-first-versus-standard-wire-escalation-strategy-for-crossing-coronary-chronic-total-occlusions-the-crossboss-first-trial
#3
Judit Karacsonyi, Peter Tajti, Bavana V Rangan, Sean C Halligan, Raymond H Allen, William J Nicholson, James E Harvey, Anthony J Spaedy, Farouc A Jaffer, J Aaron Grantham, Adam Salisbury, Anthony J Hart, David M Safley, William L Lombardi, Ravi Hira, Creighton Don, James M McCabe, M Nicholas Burke, Khaldoon Alaswad, Gerald C Koenig, Kintur A Sanghvi, Daniel Ice, Richard C Kovach, Vincent Varghese, Bilal Murad, Kenneth W Baran, Erica Resendes, Jose R Martinez-Parachini, Aris Karatasakis, Barbara A Danek, Rahel Iwnetu, Michele Roesle, Houman Khalili, Subhash Banerjee, Emmanouil S Brilakis
OBJECTIVES: The authors performed a multicenter, randomized-controlled, clinical trial comparing upfront use of the CrossBoss catheter versus antegrade wire escalation for antegrade crossing of coronary chronic total occlusions. BACKGROUND: There is equipoise about the optimal initial strategy for crossing coronary chronic total occlusions. METHODS: The primary endpoints were the time required to cross the chronic total occlusion or abort the procedure and the frequency of procedural major adverse cardiovascular events...
February 12, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29405599/wanted-expert-operators-for-coronary-chronic-total-occlusion-interventions
#4
EDITORIAL
Emmanouil S Brilakis, Oleg Krestyaninov
Coronary chronic total occlusions can be recanalized by expert operators with high success and acceptable complication rates. Developing a procedural plan (using the hybrid or another algorithm) is critical for success. Live case demonstrations appear safe and can be of high educational value. The key factor for achieving good outcomes in chronic total occlusion interventions remains operator expertise. Development of more expert operators will improve the treatment options for this challenging group of lesions and patients...
February 1, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29395703/long-term-outcomes-of-percutaneous-coronary-intervention-for-chronic-total-occlusion-in-patients-who-have-undergone-coronary-artery-bypass-grafting-vs-those-who-have-not
#5
Lorenzo Azzalini, Soledad Ojeda, Aris Karatasakis, Joren Maeremans, Masaki Tanabe, Alessio La Manna, Rustem Dautov, Luiz F Ybarra, Susanna Benincasa, Barbara Bellini, Luciano Candilio, Ozan M Demir, Francisco Hidalgo, Judit Karacsonyi, Giacomo Gravina, Eligio Miccichè, Guido D'Agosta, Giuseppe Venuti, Corrado Tamburino, Manuel Pan, Mauro Carlino, Joseph Dens, Emmanouil S Brilakis, Antonio Colombo, Stéphane Rinfret
BACKGROUND: We aimed to investigate the procedural and long-term outcomes of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) in patients who had undergone previous coronary artery bypass grafting (CABG) vs those who had not, and to evaluate the role of the Registry of CrossBoss and Hybrid procedures in France, the Netherlands, Belgium, and United Kingdom (RECHARGE) score in predicting acute and long-term outcomes. METHODS: We compiled a multicentre registry of consecutive patients undergoing CTO PCI at 7 centres between January 2009 and April 2017...
December 26, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29365623/the-correlation-of-near-infrared-spectroscopy-lipid-pools-with-computationally-measured-accumulation-of-low-density-lipoprotein-in-coronary-arteries
#6
Theodora Bampali, Lampros Lakkas, Antonis Sakellarios, Panagiotis Siogkas, John Andrikos, Anna Kotsia, Michail Papafaklis, Christos Katsouras, Dimitrios I Fotiadis, Dimitrios Karmpaliotis, Emmanouil Brilakis, Lampros Michalis
No abstract text is available yet for this article.
August 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29360064/overview-and-proposed-terminology-for-the-reverse-controlled-antegrade-and-retrograde-tracking-reverse-cart-techniques
#7
Shunsuke Matsuno, Etsuo Tsuchikane, Scott A Harding, Eugene B Wu, Hsien-Li Kao, Emmanouil S Brilakis, Kambis Mashayekhi, Gerald S Werner
During recent years, equipment and techniques for percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) have significantly improved. The retrograde approach remains critical to the improved success of CTO PCI. Currently, the reverse controlled antegrade and retrograde tracking (CART) technique has become the dominant retrograde wire crossing technique. In this article, we propose a standardized terminology and classification of this technique into 3 subtypes: a) conventional reverse CART, that usually involves use of large balloons on the antegrade wire to achieve reentry within the CTO segment; b) "directed" reverse CART which is characterized by small antegrade balloon size and more active, intentional vessel tracking and penetration with a controllable retrograde wire, still within the CTO segment; and c) "extended" reverse CART in which the intimal/ subintimal dissection is extended proximal or distal to the CTO segment, achieving reentry outside the CTO segment...
January 23, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29359452/prevalence-presentation-and-treatment-of-balloon-undilatable-chronic-total-occlusions-insights-from-a-multicenter-us-registry
#8
Peter Tajti, Dimitri Karmpaliotis, Khaldoon Alaswad, Catalin Toma, James W Choi, Farouc A Jaffer, Anthony H Doing, Mitul Patel, Ehtisham Mahmud, Barry Uretsky, Aris Karatasakis, Judit Karacsonyi, Barbara A Danek, Bavana V Rangan, Subhash Banerjee, Imre Ungi, Emmanouil S Brilakis
BACKGROUND: The prevalence, treatment and outcomes of balloon undilatable chronic total occlusions (CTOs) have received limited study. METHODS: We examined the prevalence, clinical and angiographic characteristics, and procedural outcomes of percutaneous coronary interventions (PCIs) for balloon undilatable CTOs in a contemporary multicenter US registry. RESULTS: Between 2012 and 2017 data on balloon undilatable lesions were available for 425 consecutive CTO PCIs in 415 patients in whom guidewire crossing was successful: 52 of 425 CTOs were balloon undilatable (12%)...
January 23, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29359408/the-double-stingray-technique-for-recanalizing-chronic-total-occlusions-with-bifurcation-at-the-distal-cap
#9
Peter Tajti, Darshan Doshi, Dimitri Karmpaliotis, Emmanouil S Brilakis
Antegrade dissection re-entry is often discouraged for chronic total occlusions (CTOs) with a bifurcation at the distal cap due to risk of side branch occlusion that can lead to periprocedural myocardial infarction and incomplete revascularization. Antegrade dissection re-entry, however, is often needed, especially in complex cases. We present the novel "double Stingray technique" for CTOs involving bifurcations, in which the Stingray system is used twice for re-entry into both vessel branches, followed by two-stent bifurcation stenting to maintain the patency of both branches...
January 23, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29331437/influence-of-operator-experience-and-pci-volume-on-transfemoral-access-techniques-a-collaboration-of-international-cardiovascular-societies
#10
Daniel W Nelson, Abdulla A Damluji, Nish Patel, Marco Valgimigli, Stephan Windecker, Robert Byrne, James Nolan, Tejas Patel, Emmanouil Brilakis, Subhash Banerjee, Jorge Mayol, Warren J Cantor, Carlos E Alfonso, Sunil V Rao, Mauro Moscucci, Mauricio G Cohen
INTRODUCTION: Transfemoral access (TFA) is widely used for coronary angiography and percutaneous coronary intervention (PCI). The influence of operator age, gender, experience, and procedural volume on performance of femoral arterial access has not been studied. METHODS: A survey instrument was developed and distributed via e-mail from professional societies to interventional cardiologists worldwide from March to December 2016. RESULTS: A total of 988 physicians from 88 countries responded to the survey...
December 27, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29330258/chronic-total-occlusion-percutaneous-coronary-intervention-evidence-and-controversies
#11
REVIEW
Peter Tajti, Emmanouil S Brilakis
No abstract text is available yet for this article.
January 12, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29314592/impact-of-sleep-deprivation-on-the-outcomes-of-percutaneous-coronary-intervention
#12
Ann Iverson, Larissa Stanberry, Ross Garberich, Amber Antos, Yader Sandoval, M Nicholas Burke, Ivan Chavez, Mario Gössl, Timothy D Henry, Daniel Lips, Michael Mooney, Anil Poulose, Paul Sorajja, Jay Traverse, Yale Wang, Steven Bradley, Emmanouil S Brilakis
No abstract text is available yet for this article.
January 3, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29314563/subadventitial-stenting-around-occluded-stents-a-bailout-technique-to-recanalize-in-stent-chronic-total-occlusions
#13
Lorenzo Azzalini, Aris Karatasakis, James C Spratt, Péter Tajti, Robert F Riley, Luiz F Ybarra, Stefan P Schumacher, Susanna Benincasa, Barbara Bellini, Luciano Candilio, Satoru Mitomo, Peter Henriksen, Francisco Hidalgo, Leo Timmers, Adriaan O Kraaijeveld, Pierfrancesco Agostoni, James Roy, David R Ramsay, James C Weaver, Paul Knaapen, Alexander Nap, Boris Starcevic, Soledad Ojeda, Manuel Pan, Khaldoon Alaswad, William L Lombardi, Mauro Carlino, Emmanouil S Brilakis, Antonio Colombo, Stéphane Rinfret, Kambis Mashayekhi
OBJECTIVES: To evaluate the outcomes of subadventitial stenting (SS) around occluded stents for recanalizing in-stent chronic total occlusions (IS-CTOs). BACKGROUND: There is little evidence on the outcomes of SS for IS-CTO. METHODS: We examined the outcomes of SS for IS-CTO PCI at 14 centers between July 2011 and June 2017, and compared them to historical controls recanalized using within-stent stenting (WSS). Target-vessel failure (TVF) on follow-up was the endpoint of this study, and was defined as a composite of cardiac death, target-vessel myocardial infarction, and target-vessel revascularization...
January 4, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29314555/lost-and-found-coronary-stent-retrieval-and-review-of-literature
#14
Shahbaz A Malik, Emmanouil S Brilakis, Vincent Pompili, Yiannis S Chatzizisis
A 61-year-old man with a history of percutaneous coronary intervention (PCI) of the mid right coronary artery (RCA) with a drug eluting stent (DES), presented with non-ST segment elevation myocardial infarction. Coronary angiography demonstrated complex disease of the distal RCA as well as in-stent stenosis of the previously placed mid RCA stent. The patient underwent bifurcation PCI of the distal RCA followed by attempted intervention with a DES on the mid RCA lesion. The stent could not cross the lesion and eventually became dissociated from its delivery system...
January 4, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29306468/mid-term-outcomes-of-chronic-total-occlusion-percutaneous-coronary-intervention-with-subadventitial-vs-intraplaque-crossing-a-systematic-review-and-meta-analysis
#15
Aris Karatasakis, Barbara A Danek, Judit Karacsonyi, Lorenzo Azzalini, Mauro Carlino, Stéphane Rinfret, Minh Vo, Bavana V Rangan, M N Burke, Subhash Banerjee, Emmanouil S Brilakis
BACKGROUND: Some reports have demonstrated increased risk with subadventitial chronic total occlusion (CTO) crossing, whereas others suggest equipoise between subadventitial and intraplaque crossing techniques. We sought to clarify the effect of subadventitial lesion crossing on mid-term outcomes of CTO percutaneous coronary intervention (PCI). METHODS: We conducted a systematic review and meta-analysis of studies reporting post-discharge outcomes after CTO PCI performed via subadventitial vs...
February 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29305903/-around-the-world-how-to-reach-native-coronary-artery-lesions-through-long-and-tortuous-aortocoronary-bypass-grafts
#16
EDITORIAL
Peter Tajti, Yader Sandoval, Emmanouil S Brilakis
For patients with prior coronary artery bypass graft surgery, reaching lesions in native coronary arteries distal to the anastomosis of bypass grafts can be challenging due to long distance between the graft ostium and the lesion and significant tortuosity that needs to be traversed. We describe one such lesion in a patient presenting with non-ST segment elevation myocardial infarction and cardiogenic shock. The lesion was successfully treated using a variety of strategies, including use of a short guide catheter, long guidewire, a guide catheter extension, long shaft balloons and stents, and short length stents...
January 3, 2018: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29226736/the-effect-of-major-adverse-renal-cardiovascular-event-marce-incidence-procedure-volume-and-unit-cost-on-the-hospital-savings-resulting-from-contrast-media-use-in-inpatient-angioplasty
#17
Eric Keuffel, Peter A McCullough, Thomas M Todoran, Emmanouil S Brilakis, Swetha R Palli, Michael P Ryan, Candace Gunnarsson
OBJECTIVE: Determine the net economic impact of switching from low-osmolar contrast media (LOCM) to iso-osmolar contrast media (IOCM; iodixanol) in patients undergoing inpatient coronary or peripheral angioplasty in the United States (US). METHODS: A budget impact model (BIM) was developed from a hospital perspective. Nationally representative procedural and contrast media prevalence rates, along with MARCE (major adverse renal cardiovascular event) incidence and episode-related cost data were derived from Premier Hospital Data (October 2014 to September 2015)...
December 11, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/29223954/effect-of-pcsk9-inhibitors-on-clinical-outcomes-in-patients-with-hypercholesterolemia-a-meta-analysis-of-35-randomized-controlled-trials
#18
REVIEW
Aris Karatasakis, Barbara A Danek, Judit Karacsonyi, Bavana V Rangan, Michele K Roesle, Thomas Knickelbine, Michael D Miedema, Houman Khalili, Zahid Ahmad, Shuaib Abdullah, Subhash Banerjee, Emmanouil S Brilakis
BACKGROUND: We sought to examine the efficacy and safety of 2 PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors: alirocumab and evolocumab. METHODS AND RESULTS: We performed a systematic review and meta-analysis of randomized controlled trials comparing treatment with and without PCSK9 inhibitors; 35 randomized controlled trials comprising 45 539 patients (mean follow-up: 85.5 weeks) were included. Mean age was 61.0±2.8 years, and mean baseline low-density lipoprotein cholesterol was 106±22 mg/dL...
December 9, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29207363/improvement-in-aortic-valve-area-in-patients-with-aortic-stenosis-through-use-of-a-new-hourglass-shaped-valvuloplasty-balloon
#19
Elizabeth Goldenberg, Wesley Pedersen, Emmanouil S Brilakis, Michael Mooney, Mario Gössl, Anil Poulose, Bilal Murad, James Kolbeck, Paul Sorajja
OBJECTIVES: The study aim was to assess the effect of hourglass-shaped V8 and TAV8 balloons (InterValve, Inc) on aortic valve area (AVA) and other outcomes in patients with severe aortic stenosis undergoing balloon aortic valvuloplasty (BAV). BAV has re-emerged with transcatheter therapy. Cylindrical balloons have been the device of choice despite limitations. The hourglass-shaped balloons, with shorter, broader segments separated by a narrowed waist, permit enhanced fixation and better leaflet opening without annular or sinotubular compromise...
December 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29169496/transfemoral-approach-for-coronary%C3%A2-angiography-and-intervention-a-collaboration-of-international-cardiovascular-societies
#20
Abdulla A Damluji, Daniel W Nelson, Marco Valgimigli, Stephan Windecker, Robert A Byrne, Fernando Cohen, Tejas Patel, Emmanouil S Brilakis, Subhash Banerjee, Jorge Mayol, Warren J Cantor, Carlos E Alfonso, Sunil V Rao, Mauro Moscucci, Mauricio G Cohen
OBJECTIVES: The aim of this study was to examine the current practice and use of transfemoral approach (TFA) for coronary angiography and intervention. BACKGROUND: Wide variability exists in TFA techniques for coronary procedures. METHODS: The authors developed a survey instrument that was distributed via e-mail lists from professional societies to interventional cardiologists from 88 countries between March and December 2016. RESULTS: Of 987 operators, 18% were femoralists, 38% radialists, 42% both, and 2% neither...
November 27, 2017: JACC. Cardiovascular Interventions
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