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https://www.readbyqxmd.com/read/27932876/effectiveness-of-neuromuscular-electrical-stimulation-for-the-rehabilitation-of-moderate-to-severe-copd-a-meta-analysis
#1
Rong-Chang Chen, Xiao-Ying Li, Li-Li Guan, Bing-Peng Guo, Wei-Liang Wu, Zi-Qing Zhou, Ya-Ting Huo, Xin Chen, Lu-Qian Zhou
PURPOSE: Patients with COPD often experience skeletal muscle dysfunction. For those who are unable or unwilling to undertake physical training, neuromuscular electrical stimulation (NMES) may provide an alternative method of rehabilitation. The purpose of this meta-analysis was to investigate the controversial topic of whether this therapy is effective in patients with moderate-to-severe COPD. PATIENTS AND METHODS: We pooled data from nine trials published between January 9, 2002 and January 4, 2016 across PubMed, Embase, Cochrane Central Register of Controlled Trials, Google Scholar, and relevant websites for randomized controlled trials...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27931052/a-6-week-sprint-interval-training-program-changes-anaerobic-power-quadriceps-moment-and-subcutaneous-tissue-thickness
#2
S Han, H Lee, H Kim, D Kim, C Choi, J Park
We examined the effects of a 6-week 40-m one-way sprint interval training program (based on sprint time). 13 untrained healthy male collegiate students performed six 40-m sprints with a 60-s resting interval between sprints during the first week, and one sprint was added each week until the sixth week. If the 40-m sprint time exceeded 110% of the fastest baseline 40-m sprint time, the run was repeated. Repeated-sprint cycling test (every 3 weeks), quadriceps moment (every 2 weeks), and abdominal and thigh subcutaneous tissue thickness (every 2 weeks) were measured...
December 8, 2016: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/27930453/whole-body-vibration-improves-early-rate-of-torque-development-in-individuals-with-acl-reconstruction
#3
Derek N Pamukoff, Brian Pietrosimone, Eric D Ryan, Dustin R Lee, Lee E Brown, J Troy Blackburn
The purpose of this study was to compare the effect of whole body vibration (WBV) and local muscle vibration (LMV) on early and late quadriceps rate of torque development (RTD), and electromechanical delay (EMD) in individuals with anterior cruciate ligament reconstruction (ACLR). 20 individuals with ACLR were recruited for this study. Participants performed isometric squats while being exposed to WBV, LMV, or no vibration (control) in a randomized order during separate visits. Quadriceps early and late quadriceps RTD, and EMD were assessed during a maximal voluntary isometric knee extension prior to and immediately following WBV, LMV, or control...
November 19, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27930445/motion-and-muscle-activity-are-affected-by-instability-location-during-a-squat-exercise
#4
Brian C Nairn, Chad A Sutherland, Janessa D M Drake
Squat exercise training using instability devices have become increasingly popular for a multitude of reasons. Many devices generate instability at the feet and provide a bottom-up perturbation; however, the effect of a top-down instability device during a squat remains unclear. In order to induce instability at the upper body, a water-filled cylinder called the Attitube® was used. This study analyzed the effects of instability location (top-down, bottom-up, no instability) during a squat exercise in terms of kinematics and muscle activation...
November 19, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27929469/the-colon-26-carcinoma-tumor-bearing-mouse-as-a-model-for-the-study-of-cancer-cachexia
#5
Andrea Bonetto, Joseph E Rupert, Rafael Barreto, Teresa A Zimmers
Cancer cachexia is the progressive loss of skeletal muscle mass and adipose tissue, negative nitrogen balance, anorexia, fatigue, inflammation, and activation of lipolysis and proteolysis systems. Cancer patients with cachexia benefit less from anti-neoplastic therapies and show increased mortality(1). Several animal models have been established in order to investigate the molecular causes responsible for body and muscle wasting as a result of tumor growth. Here, we describe methodologies pertaining to a well-characterized model of cancer cachexia: mice bearing the C26 carcinoma(2-4)...
November 30, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27928123/consumption-of-japanese-yam-improves-lipid-metabolism-in-high-cholesterol-diet-fed-rats
#6
Yuri Kusano, Nobuko Tsujihara, Hironori Masui, Hana Kozai, Wakako Takeuchi
We investigated the effects of dietary Japanese yam (Dioscorea japonica Thunb.) on lipid metabolism. Male Wistar rats (6 wk old) were fed a high-cholesterol diet for 6 wk and then supplemented with 26% of Japanese yam or 0.5% of its constituent diosgenin for a further 4 wk of high-cholesterol feeding (C6-J4 and C6-D4 groups, respectively). In the C6-J4 group, body weight gains significantly decreased, but skeletal muscle fiber sizes in quadriceps significantly increased compared with the other groups. Furthermore, Japanese yam supplementation resulted in the reduction of triglyceride contents in their liver, quadriceps, and intra-abdominal visceral fat...
2016: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/27926683/neuromuscular-electrical-stimulation-therapy-to-restore-quadriceps-muscle-function-in-patients-after-orthopaedic-surgery-a-novel-structured-approach
#7
Paul Spector, Yocheved Laufer, Michal Elboim Gabyzon, Andrew Kittelson, Jennifer Stevens Lapsley, Nicola A Maffiuletti
No abstract text is available yet for this article.
December 7, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27923983/sex-differences-in-function-and-structure-of-the-quadriceps-muscle-in-chronic-obstructive-pulmonary-disease-patients
#8
Pilar Ausín, Juana Martínez-Llorens, Marina Sabaté-Bresco, Carme Casadevall, Esther Barreiro, Joaquim Gea
Chronic obstructive pulmonary disease (COPD) is a complex disorder with extrapulmonary manifestations. Even though there is some knowledge regarding sex differences in the lung disease, little is known about extrapulmonary manifestations. Our aim was to analyze the specific profile of muscle dysfunction, structure, and biology in COPD women. Twenty-one women and 19 men with stable COPD as well as 15 controls were included. Nutritional status, physical activity, lung and muscle function, exercise capacity, and quality of life were assessed...
December 6, 2016: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/27923622/factors-predicting-quadriceps-femoris-muscle-atrophy-during-the-first-12weeks-following-anterior-cruciate-ligament-reconstruction
#9
T Grapar Žargi, Matej Drobnič, Renata Vauhnik, Jadran Koder, Alan Kacin
BACKGROUND: Factors predicting quadriceps femoris muscle (QF) atrophy during the early period after arthroscopic ACL reconstruction have not been extensively studied. It is also yet to be confirmed whether muscle atrophy is a key determinant of postoperative QF weakness. METHODS: Mean changes in QF volume, MVIC torque and isometric endurance time were analysed in 25 patients prior to and at four and 12 weeks after surgery. A multivariable regression model of change in QF volume was made from combination of several parameters of preoperative QF size and strength and postoperative joint recovery...
December 3, 2016: Knee
https://www.readbyqxmd.com/read/27922985/video-analysis-of-anterior-cruciate-ligament-acl-injuries-a-systematic-review
#10
Victor R Carlson, Frances T Sheehan, Barry P Boden
BACKGROUND: As the most viable method for investigating in vivo anterior cruciate ligament (ACL) rupture, video analysis is critical for understanding ACL injury mechanisms and advancing preventative training programs. Despite the limited number of published studies involving video analysis, much has been gained through evaluating actual injury scenarios. METHODS: Studies meeting criteria for this systematic review were collected by performing a broad search of the ACL literature with use of variations and combinations of video recordings and ACL injuries...
November 29, 2016: JBJS Reviews
https://www.readbyqxmd.com/read/27918690/the-advantages-of-normalizing-emg-to-ballistic-rather-than-isometric-or-isokinetic-tasks
#11
Stephen M Suydam, Kurt Manal, Thomas S Buchanan
Isometric tasks have been a standard for electromyography (EMG) normalization stemming from anatomic and physiologic stability observed during contraction. Ballistic dynamic tasks have the benefit of eliciting maximum EMG signals for normalization, despite having the potential for greater signal variability. It is the purpose of this study to compare maximum voluntary isometric contraction (MVIC) to non-isometric tasks with increasing degrees of extrinsic variability, i.e., joint range of motion, velocity, rate of contraction, etc...
December 5, 2016: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/27918084/urinary-incontinence-in-older-women-the-role-of-body-composition-and-muscle-strength-from-the-health-aging-and-body-composition-study
#12
Anne M Suskind, Peggy M Cawthon, Sanae Nakagawa, Leslee L Subak, Ilse Reinders, Suzanne Satterfield, Steve Cummings, Jane A Cauley, Tamara Harris, Alison J Huang
OBJECTIVES: To evaluate prospective relationships between body composition and muscle strength with predominantly stress urinary incontinence (SUI) and urgency urinary incontinence (UUI) in older women. DESIGN: Prospective community-dwelling observational cohort study (Health, Aging, and Body Composition study). PARTICIPANTS: Women initially aged 70 to 79 recruited from Pittsburgh, Pennsylvania, and Memphis, Tennessee (N = 1,475). MEASUREMENTS: Urinary incontinence was assessed using structured questionnaires...
December 5, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27915446/superior-dislocation-of-the-patella-a-pathognomonic-finding-and-review-of-literature
#13
P W van Egmond, M C Vermeulen, C F van Dijke, H C A Graat
A 59-year-old woman with a painful right knee that became locked in extension after a trivial trauma was seen at the emergency room. This was caused by unloaded hyperextension in bed. She was diagnosed with a superior dislocation of the patella. A closed reduction was performed, but a recurrent episode was seen within a week. An arthroscopy was performed, in which the causative osteophytes were removed. In the 12-month follow-up after treatment, no recurrence was seen. A superior dislocation of the patella is caused by patellofemoral osteophytes that interlock...
December 3, 2016: Skeletal Radiology
https://www.readbyqxmd.com/read/27913649/identification-and-function-of-fibrocytes-in-skeletal-muscle-injury-repair-and-muscular-dystrophy
#14
Xingyu Wang, Wanming Zhao, Richard M Ransohoff, Lan Zhou
We identified and characterized the function of CD45(+)/collagen I(+) fibrocytes in acutely injured skeletal muscle of wild-type (WT) and Ccr2(-/-) mice, and in quadriceps and diaphragm muscles of mdx(5cv) mice, a mouse model for Duchenne muscular dystrophy. Fibrocytes were not detected in peripheral blood of WT mice after acute muscle injury or mdx(5cv) mice. Fibrocytes were detected in acutely injured muscles and in mdx(5cv) quadriceps and diaphragm muscles. These cells expressed F4/80 and CCR2, and they were mostly Ly6C(lo) They expressed a low level of collagens but a high level of profibrotic growth factors as compared with i...
December 15, 2016: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/27909676/anatomic-double-bundle-anterior-cruciate-ligament-reconstruction-with-a-free-quadriceps-tendon-autograft
#15
Sergiu Caterev, Dan Viorel Nistor, Adrian Todor
Anatomic double-bundle anterior cruciate ligament (ACL) reconstruction aims to restore the 2 functional bundles of the ACL in an attempt to better reproduce the native biomechanics of the injured knee and promote long-term knee health. However, this concept is not fully accepted and is not performed on a standard basis. In addition, the superiority of this technique over the conventional single-bundle technique has been questioned, especially the long-term clinical results. One of the down sides of the double-bundle reconstruction is the complexity of the procedure, with increased risks, operative time, and costs compared with the single-bundle procedure...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27909674/minimally-invasive-quadriceps-tendon-harvest-and-graft-preparation-for-all-inside-anterior-cruciate-ligament-reconstruction
#16
Harris S Slone, William B Ashford, John W Xerogeanes
The quadriceps tendon is an infrequently used graft option for anterior cruciate ligament reconstruction despite favorable clinical results in the literature with low donor site morbidity. It is a versatile graft that can be harvested with bone or as a soft tissue graft alone. In addition, it can be used for anatomic, double-bundle, transtibial, and all-inside reconstructions. The unique characteristics of the quadriceps tendon allow for the ability to harvest a single-bundle large-diameter graft and minimize disruption of normal anatomy, which makes the quadriceps tendon an excellent choice for all-inside techniques...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27909143/interobserver-and-intraobserver-reliability-of-clinical-assessments-in-knee-osteoarthritis
#17
Nasimah Maricar, Michael J Callaghan, Matthew J Parkes, David T Felson, Terence W O'Neill
OBJECTIVE: Clinical examination of the knee is subject to measurement error. The aim of this analysis was to determine interobserver and intraobserver reliability of commonly used clinical tests in patients with knee osteoarthritis (OA). METHODS: We studied subjects with symptomatic knee OA who were participants in an open-label clinical trial of intraarticular steroid therapy. Following standardization of the clinical test procedures, 2 clinicians assessed 25 subjects independently at the same visit, and the same clinician assessed 88 subjects over an interval period of 2-10 weeks; in both cases prior to the steroid intervention...
December 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27907934/restriction-of-postoperative-joint-loading-in-a-murine-model-of-anterior-cruciate-ligament-reconstruction-botulinum-toxin-paralysis-and-external-fixation
#18
Amir Lebaschi, Xiang-Hua Deng, Nathan W Coleman, Christopher L Camp, Jianchun Zong, Andrew Carbone, Camila B Carballo, Guang-Ting Cong, Zoe M Album, Scott A Rodeo
Control of knee motion in small animal models is necessary to study the effect of mechanical load on the healing process. This can be especially challenging in mice, which are being increasingly used for various orthopedic reconstruction models. We explored the feasibility of botulinum toxin (Botox; Allergan, Dublin, Ireland) paralysis and a newly designed external fixator to restrict motion of the knee in mice undergoing anterior cruciate ligament (ACL) reconstruction. Nineteen C57BL/6 mice were allocated to two groups: (1) Botox group (n = 9) and (2) external fixator group (n = 10)...
December 1, 2016: Journal of Knee Surgery
https://www.readbyqxmd.com/read/27907890/association-of-muscle-endurance-fatigability-and-strength-with-functional-limitation-and-mortality-in-the-health-aging-and-body-composition-study
#19
Baback Roshanravan, Kushang V Patel, Linda F Fried, Cassianne Robinson-Cohen, Ian H de Boer, Tamara Harris, Rachel A Murphy, Suzanne Satterfield, Bret H Goodpaster, Michael Shlipak, Anne B Newman, Bryan Kestenbaum
BACKGROUND: Mobility limitation is highly prevalent among older adults and is central to the loss of functional independence. Dynamic isokinetic muscle fatigue testing may reveal increased vulnerability to disability and mortality beyond strength testing. METHODS: We studied community-dwelling older adults enrolled in the Health Aging and Body Composition study (age range: 71-82) free of mobility disability and who underwent isokinetic muscle fatigue testing in 1999-2000 (n = 1,963)...
October 21, 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/27907033/normalization-of-patient-identified-plasma-biomarkers-in-smn%C3%AE-7-mice-following-postnatal-smn-restoration
#20
W David Arnold, Sandra Duque, Chitra C Iyer, Phillip Zaworski, Vicki L McGovern, Shannon J Taylor, Katharine M von Herrmann, Dione T Kobayashi, Karen S Chen, Stephen J Kolb, Sergey V Paushkin, Arthur H M Burghes
INTRODUCTION AND OBJECTIVE: Spinal muscular atrophy (SMA) is an autosomal recessive motor neuron disorder. SMA is caused by homozygous loss of the SMN1 gene and retention of the SMN2 gene resulting in reduced levels of full length SMN protein that are insufficient for motor neuron function. Various treatments that restore levels of SMN are currently in clinical trials and biomarkers are needed to determine the response to treatment. Here, we sought to investigate in SMA mice a set of plasma analytes, previously identified in patients with SMA to correlate with motor function...
2016: PloS One
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