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https://www.readbyqxmd.com/read/29150898/a-model-to-characterize-psychopathological-features-in-adults-with-prader-willi-syndrome
#1
Denise Thuilleaux, Virginie Laurier, Pierre Copet, Julie Tricot, Geneviève Demeer, Fabien Mourre, Maithé Tauber, Joseba Jauregi
High prevalence of behavioral and psychiatric disorders in adults with Prader-Willi Syndrome (PWS) has been reported in last few years. However, data are confusing and often contradictory. In this article, we propose a model to achieve a better understanding of the psychopathological features in adults with PWS. The study is based on clinical observations of 150 adult inpatients, males and females. Non-parametric statistics were performed to analyse the association of psychopathological profiles with genotype, gender and age...
November 17, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29149969/indicators-of-complex-care-during-the-consultation-liaison-psychiatry-activity-at-the-transplant-center-of-the-policlinico-hospital-modena
#2
G Mattei, A Laghi, S Balduzzi, M Moscara, C Piemonte, C Reggianini, M Rigatelli, S Ferrari, L Pingani, G M Galeazzi
OBJECTIVE: The objective of this study was to identify possible biopsychosocial predictors of organizational complexity in patients referred to the consultant psychiatrist for assessment before liver transplantation. METHODS: This was a case-control study. All psychiatric consultations performed before and after liver transplantation from January 1, 2008 to December 31, 2013 were included. Complexity was operationalized as "undergoing two or more psychiatric consultations"...
November 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29149114/-calls-due-to-suicidal-behaviour-made-to-the-prehospital-emergency-department-in-m%C3%A3-laga-characteristics-and-associated-factors
#3
M Jiménez-Hernández, S Castro-Zamudio, J Guzmán Parra, A I Martínez-García, C Guillén-Benítez, B Moreno-Küstner
BACKGROUND: Suicidal behaviour (fatal and non-fatal) has become a serious public health problem in many countries. The aim of the study was to describe the differential characteristics of emergency calls due to suicidal behaviour made to the Emergency Coordinating Centre (CCUE) in the province of Málaga, in comparison with calls due to physical or psychiatric problems. METHODS: Retrospective observational study of the calls recorded in the database of the Public Company for Emergency Health during one year...
November 17, 2017: Anales del Sistema Sanitario de Navarra
https://www.readbyqxmd.com/read/29143367/risk-of-death-associated-with-new-benzodiazepine-use-among-persons-with-alzheimer-disease-a-matched-cohort-study
#4
Laura Saarelainen, Anna-Maija Tolppanen, Marjaana Koponen, Antti Tanskanen, Jari Tiihonen, Sirpa Hartikainen, Heidi Taipale
OBJECTIVE: To investigate the risk of death associated with new benzodiazepine and related drug (BZDR) use in a nationwide cohort of persons with Alzheimer disease (AD). METHODS: The register-based MEDALZ cohort, including all community-dwelling Finns diagnosed with AD during 2005 to 2011 (n = 70 718), was used. Clinically verified AD diagnoses were obtained from the Special Reimbursement Register. Drug use periods were modeled from BZDR purchases, derived from the Prescription Register...
November 15, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29142105/the-nde1-genomic-locus-can-affect-treatment-of-psychiatric-illness-through-gene-expression-changes-related-to-microrna-484
#5
Nicholas J Bradshaw, Liisa Ukkola-Vuoti, Maiju Pankakoski, Amanda B Zheutlin, Alfredo Ortega-Alonso, Minna Torniainen-Holm, Vishal Sinha, Sebastian Therman, Tiina Paunio, Jaana Suvisaari, Jouko Lönnqvist, Tyrone D Cannon, Jari Haukka, William Hennah
Genetic studies of familial schizophrenia in Finland have observed significant associations with a group of biologically related genes, DISC1, NDE1, NDEL1, PDE4B and PDE4D, the 'DISC1 network'. Here, we use gene expression and psychoactive medication use data to study their biological consequences and potential treatment implications. Gene expression levels were determined in 64 individuals from 18 families, while prescription medication information has been collected over a 10-year period for 931 affected individuals...
November 2017: Open Biology
https://www.readbyqxmd.com/read/29137173/psychiatric-disorders-differently-correlate-with-physical-self-rated-health-across-ethnic-groups
#6
Shervin Assari
In this study, we compared 10 ethnic groups for associations between psychiatric disorders and physical self-rated health (SRH) in the United States. Data came from the Collaborative Psychiatric Epidemiology Surveys (CPES), 2001-2003. The study included 7587 non-Latino White, 4746 African American, 1442 Mexican, 1106 other Hispanic, 656 other Asian, 600 Chinese, 577 Cuban, 520 Vietnamese, 508 Filipino, and 495 Puerto Rican individuals. The Composite International Diagnostic Interview (CIDI) was used to measure psychiatric disorders, including major depressive disorder (MDD), general anxiety disorder (GAD), social phobia, panic disorder, post-traumatic stress disorder (PTSD), alcohol abuse, and binge eating disorders...
November 13, 2017: Journal of Personalized Medicine
https://www.readbyqxmd.com/read/29135294/-study-of-socio-demographic-factors-in-the-treatment-of-unipolar-major-depression-in-a-follow-up-clinical-trial
#7
Melinda Ferencz, Sándor Csibi, József Gabos Grecu
INTRODUCTION: Depression is one of the most widespread illnesses of our time, currently affecting more than 300 million people worldwide. Literature identifies several socio-demographic risk factors in the development of the depression. AIM: We aim to examine the socio-demographic factors involved in the remission of clinically diagnosed unipolar major depression. METHOD: Data collection was performed during 2016, at the 1st Psychiatric Clinic from Tirgu Mures...
October 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/29131655/psychotropic-drug-prescription-in-adolescents-a-retrospective-study-in-a-swiss-psychiatric-university-hospital
#8
Nicolas Ansermot, Véronique Jordanov, Michal Smogur, Laurent Holzer, Chin B Eap
OBJECTIVES: This retrospective study aims to evaluate off-label prescriptions and administrations of psychotropic medications in adolescents in a university psychiatric hospital in Switzerland. METHODS: Data were collected during the entire stays from the electronic database for 76 inpatients in 2008 and 76 inpatients in 2014. Data collected included gender, age, psychiatric diagnosis, duration of hospitalization, and psychotropic drug prescriptions and administrations...
November 13, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29126787/anxiety-disorders-in-old-age-psychiatric-comorbidities-quality-of-life-and-prevalence-according-to-age-gender-and-country
#9
EDITORIAL
Aartjan T F Beekman
No abstract text is available yet for this article.
October 12, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29122037/grey-matter-volume-and-thickness-abnormalities-in-young-people-with-a-history-of-childhood-abuse
#10
L Lim, H Hart, M Mehta, A Worker, A Simmons, K Mirza, K Rubia
BACKGROUND: Childhood abuse is associated with abnormalities in brain structure and function. Few studies have investigated abuse-related brain abnormalities in medication-naïve, drug-free youth that also controlled for psychiatric comorbidities by inclusion of a psychiatric control group, which is crucial to disentangle the effects of abuse from those associated with the psychiatric conditions. METHODS: Cortical volume (CV), cortical thickness (CT) and surface area (SA) were measured in 22 age- and gender-matched medication-naïve youth (aged 13-20) exposed to childhood abuse, 19 psychiatric controls matched for psychiatric diagnoses and 27 healthy controls...
November 10, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29121554/age-of-onset-of-non-suicidal-self-injury-in-dutch-speaking-adolescents-and-emerging-adults-an-event-history-analysis-of-pooled-data
#11
Amarendra Gandhi, Koen Luyckx, Imke Baetens, Glenn Kiekens, Ellen Sleuwaegen, Ann Berens, Shubhada Maitra, Laurence Claes
OBJECTIVE: Non-Suicidal Self-Injury (NSSI) has emerged as an important mental-health concern. However, epidemiological features like age of onset of NSSI have remained understudied. Therefore, the current study investigated the distribution of age of onset of NSSI in pooled sample of Dutch-speaking adolescents and emerging adults using event history analysis. METHOD: Eleven datasets measuring age at first NSSI in community and clinical participants collected by researchers in the Dutch-speaking part of Belgium were pooled together...
October 20, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29120850/aggression-as-an-independent-entity-even-in-psychosis-the-role-of-cortisol
#12
Sourav Das, Soumik Sengupta, Kangkan Pathak, Divyashree Sah, Sumit Mehta, Priya Ranjan Avinash, Aparajeeta Baruah, Sailendra Kumar Deuri, Anil Sarmah, Vijay Gogoi, Kamal Narayan Kalita, Jyoti Hazarika
Aggression is a common entity in psychiatric disorders, particularly psychotic disorders. Glucocorticoid hypofunction has been linked to abnormal forms of aggressive behavior in various studies in a 'possibly causal' role. We hypothesise that aggression, even among those having psychosis is associated with glucocorticoid alterations similar to those who are aggressive but not psychotic. To our knowledge, this is the first study attempting to look at the cortisol functioning in relation to both aggression and psychosis...
November 8, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29107956/estradiol-increases-the-sensitivity-of-ventral-tegmental-area-dopamine-neurons-to-dopamine-and-ethanol
#13
Bertha J Vandegrift, Chang You, Rosalba Satta, Mark S Brodie, Amy W Lasek
Gender differences in psychiatric disorders such as addiction may be modulated by the steroid hormone estrogen. For instance, 17β-estradiol (E2), the predominant form of circulating estrogen in pre-menopausal females, increases ethanol consumption, suggesting that E2 may affect the rewarding properties of ethanol and thus the development of alcohol use disorder in females. The ventral tegmental area (VTA) is critically involved in the rewarding and reinforcing effects of ethanol. In order to determine the role of E2 in VTA physiology, gonadally intact female mice were sacrificed during diestrus II (high E2) or estrus (low E2) for electrophysiology recordings...
2017: PloS One
https://www.readbyqxmd.com/read/29106793/body-mass-index-and-plasma-leptin-in-psychiatric-suicide-attempters
#14
(no author information available yet)
OBJECTIVES: To evaluate body mass index (BMI) and its correlate plasma leptin levels that have been associated with psychiatric morbidity and suicidal behaviour, in relation to clinical features in psychiatric patients after a suicide attempt. METHODS: BMI and plasma leptin were assessed in 198 patients (66 males, age range of 21 to 80 years) who were admitted to the hospital after a suicide attempt, 98 with major depressive disorder, 28 with bipolar disorder, 30 with psychosis, and 42 with personality or adjustment disorder, compared to data of 134 healthy subjects, and evaluated in relation to gender, diagnosis, mode of attempt, and pharmacological treatment before attempt...
October 6, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29102817/low-frequency-fluctuation-of-brain-spontaneous-activity-and-obsessive-compulsive-symptoms-in-a-large-school-age-sample
#15
Marcelo Q Hoexter, Claudinei E Biazoli, Pedro G Alvarenga, Marcelo C Batistuzzo, Giovanni A Salum, Ary Gadelha, Pedro M Pan, Mauricio Anés, Leticia Mancini-Martins, Luciana M Moura, Carles Soriano-Mas, Marco A G Del' Aquilla, Edson Amaro, Luis A Rohde, Andrea P Jackowski, Rodrigo A Bressan, Euripedes C Miguel, Maria C do Rosario, João R Sato
BACKGROUND: The present study was designed to explore alterations in brain dynamics at rest that are associated with Obsessive Compulsive Symptoms (OCS) in childhood by measuring low frequency fluctuation of spontaneous brain activity in a large school community sample from a developing country. METHOD: Resting state functional magnetic resonance imaging data were collected in a sample of 655 children and adolescents (6-15 years old) from the brazilian 'High Risk Cohort Study for Psychiatric Disorders (HRC)'...
October 16, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29102308/suicidal-ideation-in-a-community-derived-sample-of-spanish-adolescents
#16
Eduardo Fonseca-Pedrero, Félix Inchausti, Laura Pérez-Gutiérrez, Rebeca Aritio Solana, Javier Ortuño-Sierra, M ª Ángeles Sánchez-García, Beatriz Lucas-Molina, César Domínguez, David Foncea, Virginia Espinosa, Ana Gorría, Elena Urbiola-Merina, Marta Fernández, Carmen Merina Díaz, Carmen Gutiérrez, Marta Aures, María S Campos, Elena Domínguez-Garrido, Alicia Pérez de Albéniz Iturriaga
INTRODUCTION: Suicide is a current public health problem and among the main causes of mortality in adolescents and young adults. The main goal of this study was to analyse suicidal ideation in a representative sample of Spanish adolescents. Specifically, the prevalence rates of suicide ideation, the psychometric properties of the Paykel Suicide Scale (PSS) scores, and the socio-emotional adjustment of adolescents at risk for suicide were analysed. MATERIAL AND METHODS: The sample consisted of 1,664 participants (M=16...
October 26, 2017: Revista de Psiquiatrí́a y Salud Mental
https://www.readbyqxmd.com/read/29099546/the-diagnostic-challenge-of-the-late-onset-frontal-lobe-syndrome-clinical-predictors-for-primary-psychiatric-disorders-versus-behavioral-variant-frontotemporal-dementia
#17
Everard G B Vijverberg, Flora Gossink, Welmoed Krudop, Sietske Sikkes, Cora Kerssens, Niels Prins, Max Stek, Philip Scheltens, Yolande Pijnenburg, Annemiek Dols
OBJECTIVE: Primary psychiatric disorders (PsD) can present with symptomatology identical to that of behavioral variant frontotemporal dementia (bvFTD). To date, clinical guidelines do not provide a solution for this diagnostic challenge. The aim of our study was to prospectively determine which demographic, clinical, neuropsychological, neuroimaging, and cerebrospinal fluid biomarkers are important in distinguishing PsD from bvFTD. METHODS: Patients with late-onset behavioral disturbances (aged 45-75 years, 73% male) were included based on their scores on the Frontal Behavioral Inventory and the Stereotypy Rating Inventory and followed for 2 years from April 2011 to June 2015...
October 31, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29099545/evaluation-of-the-body-parts-that-preoccupy-adolescents-with-body-dysmorphic-disorder
#18
Mohammad Jafferany, Ferdnand C Osuagwu
Objective: To evaluate which body parts preoccupy adolescents with body dysmorphic disorder (BDD). Methods: Patients admitted to an inpatient psychiatric hospital who agreed to take part in the study completed the Body Dysmorphic Disorder Questionnaire (child and adolescent version) and Body Dysmorphic Disorder Diagnostic Module. Patients also completed a questionnaire that addressed age at onset, coping strategies, history of sexual abuse, amount of time patients spent thinking about their perceived defects, and the area of the body that the participants were preoccupied with and the specific coping strategy used...
October 26, 2017: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/29099540/depression-and-anxiety-in-patients-undergoing-left-ventricular-assist-device-implantation
#19
Scott Lundgren, Cecilia Y M Poon, Ahmed Selim, Brian D Lowes, Ronald Zolty, Adam Burdorf, Yael Potashnik-Peled, Michael J Moulton, John Y Um, Eugenia Raichlin
BACKGROUND: Depression and anxiety are associated with a worse prognosis in heart failure patients. The aim of this study was to identify the prevalence of depression and anxiety in left ventricular assist device (LVAD) candidates and assess their effect on post-LVAD outcomes. METHODS: Based on the pre-LVAD psychological assessment, the total cohort of 246 patients were divided into 4 groups: 1) no depression or anxiety (NDep&Anx group, n = 138); 2) isolated depression (Dep group, n = 42); 3) isolated anxiety (Anx group, n = 32), and 4) combined depression and anxiety (Dep&Anx group, n = 34)...
November 1, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/29094261/a-preliminary-report-on-psychiatric-impairments-and-quality-of-life-among-kaohsiung-gas-explosion-victims-6-months-after-the-event
#20
Joh-Jong Huang, Tsyr-En Grace Wu, Yi-Chen Chen, Ju-Yu Chiu, Pesus Chou, Frank Huang-Chih Chou
OBJECTIVE: To investigate the prevalence and related risk factors for probable disaster-related psychiatric disorders, such as major depressive episodes (MDEs) and posttraumatic stress disorder (PTSD), among the victims of a petrochemical gas explosion in Kaohsiung, Taiwan, 6 months after the event. Additionally, the quality of life (QOL) of victims with related risk factors was simultaneously investigated. METHODS: A community-based screening survey with cross-sectional assessments was conducted...
November 1, 2017: Quality of Life Research
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