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https://www.readbyqxmd.com/read/28807073/a-comparison-of-paramedic-first-pass-endotracheal-intubation-success-rate-of-the-vividtrac-vt-a-100-glidescope-ranger-and-direct-laryngoscopy-under-simulated-prehospital-cervical-spinal-immobilization-conditions-in-a-cadaveric-model
#1
Ryan Hodnick, Tony Zitek, Kellen Galster, Stephen Johnson, Bryan Bledsoe, Daniel Ebbs
OBJECTIVE: The primary goal of this study was to compare paramedic first pass success rate between two different video laryngoscopes and direct laryngoscopy (DL) under simulated prehospital conditions in a cadaveric model. METHODS: This was a non-randomized, group-controlled trial in which five non-embalmed, non-frozen cadavers were intubated under prehospital spinal immobilization conditions using DL and with both the GlideScope Ranger (GL; Verathon Inc, Bothell, Washington USA) and the VividTrac VT-A100 (VT; Vivid Medical, Palo Alto, California USA)...
August 15, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28805805/whole-tumor-section-quantitative-image-analysis-maximizes-between-pathologists-reproducibility-for-clinical-immunohistochemistry-based-biomarkers
#2
Michael Barnes, Chukka Srinivas, Isaac Bai, Judith Frederick, Wendy Liu, Anindya Sarkar, Xiuzhong Wang, Yao Nie, Bryce Portier, Monesh Kapadia, Olcay Sertel, Elizabeth Little, Bikash Sabata, Jim Ranger-Moore
Pathologists have had increasing responsibility for quantitating immunohistochemistry (IHC) biomarkers with the expectation of high between-reader reproducibility due to clinical decision-making especially for patient therapy. Digital imaging-based quantitation of IHC clinical slides offers a potential aid for improvement; however, its clinical adoption is limited potentially due to a conventional field-of-view annotation approach. In this study, we implemented a novel solely morphology-based whole tumor section annotation strategy to maximize image analysis quantitation results between readers...
August 14, 2017: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/28794842/mega-acer-kit%C3%A2-is-more-effective-for-warming-the-intravenous-fluid-than-ranger%C3%A2-and-thermosens%C3%A2-at-440-ml-h-of-infusion-rate-an-experimental-performance-study
#3
Dong Joon Kim, Sang Hun Kim, Keum Young So, Tae Hun An
BACKGROUND: Few studies have investigated the effectiveness of intravenous fluid warmers at low and moderate flow rates below 1,000 ml/h. In this study, we compared the effectiveness of three different fluid warmers at a low flow rate (440 ml/h). METHODS: We experimentally investigated the fluid warming performances of Mega Acer Kit® (Group M, n = 10), Ranger™ (Group R, n = 10), and ThermoSens® (Group T, n = 10) at 440 ml/h for 60 min. All devices were set at a warming temperature of 41℃ with preheating for 10 min...
August 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/28780512/repeated-administration-of-dapirolizumab-pegol-in-a-randomised-phase-i-study-is-well-tolerated-and-accompanied-by-improvements-in-several-composite-measures-of-systemic-lupus-erythematosus-disease-activity-and-changes-in-whole-blood-transcriptomic-profiles
#4
Chris Chamberlain, Peter J Colman, Ann M Ranger, Linda C Burkly, Geoffrey I Johnston, Christian Otoul, Christian Stach, Miren Zamacona, Thomas Dörner, Murray Urowitz, Falk Hiepe
OBJECTIVES: Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease associated with diffuse immune cell dysfunction. CD40-CD40 ligand (CD40L) interaction activates B cells, antigen-presenting cells and platelets. CD40L blockade might provide an innovative treatment for systemic autoimmune disorders. We investigated the safety and clinical activity of dapirolizumab pegol, a polyethylene glycol conjugated anti-CD40L Fab' fragment, in patients with SLE. METHODS: This 32-week randomised, double-blind, multicentre study (NCT01764594) evaluated repeated intravenous administration of dapirolizumab pegol in patients with SLE who were positive for/had history of antidouble stranded DNA/antinuclear antibodies and were on stable doses of immunomodulatory therapies (if applicable)...
August 5, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28756299/is-the-size-and-composition-of-the-paraspinal-muscles-associated-with-low-back-pain-a-systematic-review
#5
REVIEW
Tom A Ranger, Flavia M Cicuttini, Tue Secher Jensen, Waruna L Peiris, Sultana Monira Hussain, Jessica Fairley, Donna M Urquhart
Background Context Although previous studies have investigated the association between paraspinal muscle morphology and low back pain (LBP), the results are conflicting. Purpose This systematic review examined the relationship between size and composition of the paraspinal muscles and LBP. Study design/ setting: Systematic review Patient sample: N/A Outcome measures: N/A Methods A systematic search of electronic databases was conducted to identify studies investigating the association between the cross-sectional area and/or fatty infiltration of the paraspinal muscles (erector spinae, multifidus, psoas and quadratus lumborum) and LBP...
July 26, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28715355/repeated-exposure-to-sucrose-for-procedural-pain-in-mouse-pups-leads-to-long-term-widespread-brain-alterations
#6
Sophie Tremblay, Manon Ranger, Cecil M Y Chau, Jacob Ellegood, Jason P Lerch, Liisa Holsti, Daniel Goldowitz, Ruth E Grunau
Oral sucrose is administered routinely to reduce pain of minor procedures in premature infants and is recommended as standard care in international guidelines. No human or animal studies on effects of early repeated sucrose exposure on long-term brain development have been done in the context of pain. We evaluated the effects of repeated neonatal sucrose treatment before an intervention on long-term brain structure in mouse pups. Neonatal C57Bl/6J mice (n = 109) were randomly assigned to one of 2 treatments (vehicle vs sucrose) and one of 3 interventions (handling, touch, or needle-prick)...
August 2017: Pain
https://www.readbyqxmd.com/read/28702154/a-case-report-on-late-presentation-of-occult-dural-lesions
#7
Timothy J Cochrane, Gurpreet Singh Ranger
BACKGROUND: Occult dural injuries are rare and can occur as a result of major or minor head injury. These injuries usually manifest with cerebrospinal fluid rhinorrhea alone, or with meningitis and cerebral abscess, sometimes many years after the original injury. CASE PRESENTATION: We present a case of occult dural injury with endocranial complications which occurred in a 34 year old man, with a history of head injury forty-three years ago. The patient presented with a triad of findings; meningitis, CSF rhinorrhoea and pneumocephalus...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28667292/identification-of-a-functionally-significant-tri-allelic-genotype-in-the-tyrosinase-gene-tyr-causing-hypomorphic-oculocutaneous-albinism-oca1b
#8
Chelsea S Norman, Luke O'Gorman, Jane Gibson, Reuben J Pengelly, Diana Baralle, J Arjuna Ratnayaka, Helen Griffiths, Matthew Rose-Zerilli, Megan Ranger, David Bunyan, Helena Lee, Rhiannon Page, Tutte Newall, Fatima Shawkat, Christopher Mattocks, Daniel Ward, Sarah Ennis, Jay E Self
Oculocutaneous albinism (OCA) and ocular albinism (OA) are inherited disorders of melanin biosynthesis, resulting in loss of pigment and severe visual deficits. OCA encompasses a range of subtypes with overlapping, often hypomorphic phenotypes. OCA1 is the most common cause of albinism in European populations and is inherited through autosomal recessive mutations in the Tyrosinase (TYR) gene. However, there is a high level of reported missing heritability, where only a single heterozygous mutation is found in TYR...
June 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28657858/screening-for-bovine-tuberculosis-in-african-buffalo-syncerus-caffer-in-ngorongoro-conservation-area-northern-tanzania-implications-for-public-health
#9
Bugwesa Z Katale, Robert D Fyumagwa, Eblate E Mjingo, Kuya Sayalel, Emmanuel K Batamuzi, Mecky I Matee, Julius D Keyyu, Justice Muumba, Maulid Mdaki, Erasto V Mbugi, Mark M Rweyemamu, Donald G Mpanduji
In the Ngorongoro Conservation Area (NCA), Tanzania, where wildlife and livestock interaction is intense, greater potential for intra- and interspecies disease transmission is expected. We assessed the prevalence of bovine tuberculosis in African buffalo (Syncerus caffer) residing on the valley floor of the crater in the NCA. Apparently healthy animals were randomly selected from herds in nine sites of the Ngorongoro Crater. Syncerus caffer buffalo herds were located using very high-frequency radio-aided rangers positioned in various observation points around the crater in the NCA...
June 28, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28631400/effects-of-uranium-concentration-on-microbial-community-structure-and-functional-potential
#10
Brodie Sutcliffe, Anthony A Chariton, Andrew J Harford, Grant C Hose, Greenfield Paul, Liam D H Elbourne, Yalchin Oytam, Sarah Stephenson, David J Midgley, Ian T Paulsen
Located in the Northern Territory of Australia, Ranger uranium mine is directly adjacent to the UNESCO World Heritage listed Kakadu National Park, with rehabilitation targets needed to ensure the site can be incorporated into the park following the mine's closure in 2026. This study aimed to understand the impact of uranium concentration on microbial communities, in order to identify and describe potential breakpoints in microbial ecosystem services. This is the first study to report in situ deployment of uranium-spiked sediments along a concentration gradient (0 - 4,000 mg U/kg), with the study design maximising the advantages of both field surveys and laboratory manipulative studies...
June 19, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28630743/comparison-of-five-video-assisted-intubation-devices-by-novice-and-expert-laryngoscopists-for-use-in-the-aeromedical-evacuation-environment
#11
Matthew C Wallace, SSgt Tyler Britton, Robbie Meek, Sharon Walsh-Hart, Col Todd E Carter, Steven J Lisco
BACKGROUND: The critically ill or injured patient undergoing military medical evacuation may require emergent intubation. Intubation may be life-saving, but it carries risks. The novice or infrequent laryngoscopist has a distinct disadvantage because experience is critical for the rapid and safe establishment of a secured airway. This challenge is compounded by the austere environment of the back of an aircraft under blackout conditions. This study determined which of five different video-assisted intubation devices (VAIDs) was best suited for in-flight use by U...
2017: Military Medical Research
https://www.readbyqxmd.com/read/28601204/battlefield-analgesia-in-tactical-combat-casualty-care
#12
REVIEW
Ian S Wedmore, Frank K Butler
At the start of the Afghanistan conflict, battlefield analgesia for US military casualties was achieved primarily through the use of intramuscular (IM) morphine. This is a suboptimal choice, since IM morphine is slow-acting, leading to delays in effective pain relief and the risk of overdose and death when dosing is repeated in order to hasten the onset of analgesia. Advances in battlefield analgesia, pioneered initially by Tactical Combat Casualty Care (TCCC), and the Army's 75th Ranger Regiment, have now been incorporated into the Triple-Option Analgesia approach...
June 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28599034/a-prospective-randomized-controlled-two-arm-clinical-study-evaluating-the-efficacy-of-a-bioelectric-dressing-system-for-blister-management-in-us-army-ranger-recruits
#13
Greggory J Housler, Sue Cross, Vanessa Marcel, Daniel O Kennedy, Michael Husband, Andrew Register, Thomas Roberts, Seth Grubbs, Douglas Dudewicz, Nathan Setka, Curt Bay, Martin E Wendelken, Mina J Izadjoo
This study focused on a clinically relevant healthcare problem in the military: acute soft tissue wounds, or blisters. The trial was a prospective, controlled, randomized two-arm study evaluating the efficacy of a bioelectric dressing, Procellera®, applied topically two to three times per week for 2 weeks to blisters developed in Ranger trainees during training at Fort Benning, Georgia. A total of 80 US Army Ranger recruits with blister wounds below the knee were randomly assigned to one of two treatment groups (n = 40/group)...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/28558502/six-month-results-from-the-initial-randomized-study-of-the-ranger-paclitaxel-coated-balloon
#14
Yvonne Bausback, Andrea Willfort-Ehringer, Horst Sievert, Volker Geist, Michael Lichtenberg, Costantino Del Giudice, Antoine Sauguet, Juan Diaz-Cartelle, Claudia Marx, Armin Ströbel, Ingolf Schult, Dierk Scheinert
PURPOSE: To evaluate the performance of the Ranger paclitaxel-coated balloon vs uncoated balloon angioplasty for femoropopliteal lesions. METHODS: Between January 2014 and October 2015, the prospective, randomized RANGER SFA study ( ClinicalTrials.gov identifier NCT02013193) enrolled 105 patients with symptomatic lower limb ischemia (Rutherford category 2-4) and stenotic lesions in the nonstented femoropopliteal segment at 10 European centers. Seventy-one patients (mean age 68±8 years; 53 men) were enrolled in the Ranger drug-coated balloon (DCB) arm and 34 patients (mean age 67±9 years; 23 men) were assigned to the control group...
May 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/28528654/natural-radionuclides-and-stable-elements-in-weaver-ants-oecophylla-smaragdina-from-tropical-northern-australia
#15
Peter Medley, Che Doering, Fiona Evans, Andreas Bollhöfer
Natural radionuclides and stable elements were measured in weaver ants, leaves and soils collected from three sites in tropical northern Australia. Radionuclide concentration ratios for ants relative to soil were derived from the measurements and used to refine the current environmental radiological assessment for remediation of Ranger uranium mine. Use of site-specific concentration ratios for weaver ants gave a more conservative estimate of environmental exposure to the arthropod wildlife group than use of default concentration ratios in the ERICA Tool...
May 18, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28527951/digital-food-photography-technology-improves-efficiency-and-feasibility-of-dietary-intake-assessments-in-large-populations-eating-ad-libitum-in-collective-dining-facilities
#16
Holly L McClung, Catherine M Champagne, H Raymond Allen, Susan M McGraw, Andrew J Young, Scott J Montain, Aaron P Crombie
BACKGROUND: Accurate assessment of dietary intake continues to challenge researchers, especially in field, or non-laboratory settings. OBJECTIVE: In this study, digital food photography (DFP) methodology was used to assess nutritional intake (NI) of Soldiers participating in the US Army's Ranger Selection and Assessment Program (RASP). METHODS: During this high-intensity six-week course, Soldiers complete simulated operational missions, perform various military tasks, and importantly, eating time is severely limited...
May 17, 2017: Appetite
https://www.readbyqxmd.com/read/28474770/analysing-model-fit-of-psychometric-process-models-an-overview-a-new-test-and-an-application-to-the-diffusion-model
#17
Jochen Ranger, Jörg-Tobias Kuhn, Carsten Szardenings
Cognitive psychometric models embed cognitive process models into a latent trait framework in order to allow for individual differences. Due to their close relationship to the response process the models allow for profound conclusions about the test takers. However, before such a model can be used its fit has to be checked carefully. In this manuscript we give an overview over existing tests of model fit and show their relation to the generalized moment test of Newey (Econometrica, 53, 1985, 1047) and Tauchen (J...
May 2017: British Journal of Mathematical and Statistical Psychology
https://www.readbyqxmd.com/read/28452292/body-weight-and-body-composition-changes-during-military-training-and-deployment-involving-the-use-of-combat-rations-a-systematic-literature-review
#18
REVIEW
Eliza C Tassone, Bradley A Baker
Dismounted military personnel operate in physically and psychologically demanding environments, with energy intake from combat rations often falling short of their requirements, leading to reductions in body weight and changes in body composition, which can impact both their health and performance. This review systematically investigated the effects of the continual use of combat rations for periods of 3-40 d on body weight and/or body composition in military personnel engaged in training or deployment. In all, ten databases were searched from their inception until October 2016...
March 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28447813/using-response-time-data-to-reduce-testing-time-in-cognitive-tests
#19
Maria Bertling, Jonathan P Weeks
Achievement estimates are often based on either number correct scores or IRT-based ability parameters. Van der Linden (2007) and other researchers (e.g., Fox, Klein Entink, & van der Linden, 2007; Ranger, 2013) have developed psychometric models that allow for joint estimation of speed and item parameters using both response times and response data. This paper presents an application of this type of approach to a battery of 4 types of fluid reasoning measures, administered to a large sample of a highly educated examinees...
April 27, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28345681/-studies-on-lyme-disease-incidence-rates-in-selected-groups-of-forestry-workers-in-west-pomerania-2005-2014
#20
Tomasz Stawicki
BACKGROUND: The data collected by sanitary-epidemiological stations in 2005-2014 were analyzed to determine the incidence rates of borreliosis Lyme disease in the West Pomerania group of workers exposed to tick bites. MATERIAL AND METHODS: It was assumed that an adequate comparison of official epidemiological data with the data concerning the number of exposed people, is an indispensable condition for assessing properly the trend in Lyme disease incidence rates, concerning at the same time a real scale of occupational exposure...
March 24, 2017: Medycyna Pracy
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