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https://www.readbyqxmd.com/read/29787695/incidence-of-musculoskeletal-injury-in-us-army-unit-types-a-prospective-cohort-study
#1
Deydre S Teyhen, Stephen L Goffar, Scott W Shaffer, Kyle Kiesel, Robert J Butler, Ann-Maree Tedaldi, Jennifer C Prye, Daniel I Rhon, Phillip J Plisky
Study Design A prospective observational cohort. Background Musculoskeletal injuries during military service are a primary source of disability resulting in 2.4 million annual health care visits and 25 million limited-duty days. While the injury incidence during basic training is well documented there is little understanding of injury distribution by organization type in the Army following initial training. Objective Compare injury incidence, distribution, and impact across various military units. Methods Comprehensive injury data from subject questionnaires and medical chart reviews were collected for 1430 initially healthy Army personnel representing combat, combat support, combat service support, and ranger units over 12 months...
May 22, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29780248/incidence-of-symptomatic-venous-thromboembolism-in-2372-knee-and-hip-replacement-patients-after-discharge-data-from-a-thromboprophylaxis-registry-in-montreal-canada
#2
Andréa Senay, Milanne Trottier, Josée Delisle, Andreea Banica, Benoit Benoit, G Yves Laflamme, Michel Malo, Hai Nguyen, Pierre Ranger, Julio C Fernandes
Background: Low-molecular-weight heparin (LMWH) is a recommended anticoagulant for thromboprophylaxis after major orthopedic surgery. Dabigatran etexilate is an oral anticoagulant recognized as noninferior to LMWH. We aimed to assess the incidence of symptomatic venous thromboembolic events (VTEs) after discharge in patients who underwent joint replacement, using a hospital registry. Patients and methods: Patients who underwent total knee and hip arthroplasty between September 2011 and March 2015 were selected...
2018: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29757357/the-revival-of-the-gini-importance
#3
Stefano Nembrini, Inke R König, Marvin N Wright
Motivation: Random forests are fast, flexible and represent a robust approach to analyze high dimensional data. A key advantage over alternative machine learning algorithms are variable importance measures, which can be used to identify relevant features or perform variable selection. Measures based on the impurity reduction of splits, such as the Gini importance, are popular because they are simple and fast to compute. However, they are biased in favor of variables with many possible split points and high minor allele frequency...
May 10, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29742579/congenital-calvarial-hemangioma
#4
Michal Brichacek, Abdul Naeem, Guido Filler, Robert Hammond, Arjang Yazdani, Adrianna Ranger
OBJECTIVES: The authors describe a case of congenital calvarial hemangioma successfully managed using propranolol therapy. Presenting symptoms, radiological and pathological features, differential diagnosis, and management of this rare congenital mass are described. CASE PRESENTATION: A 2-year-old boy presented with a 1-year history of a growing right parietal skull mass. No obvious etiology was apparent. No focal neurological deficits or associated craniofacial anomalies were identified...
May 8, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29738609/potential-of-electric-bicycles-to-improve-the-health-of-people-with-type-2-diabetes-a-feasibility-study
#5
A R Cooper, B Tibbitts, C England, D Procter, A Searle, S J Sebire, E Ranger, A S Page
AIM: To explore in a feasibility study whether 'e-cycling' was acceptable to, and could potentially improve the health of, people with Type 2 diabetes. METHODS: Twenty people with Type 2 diabetes were recruited and provided with an electric bicycle for 20 weeks. Participants completed a submaximal fitness test at baseline and follow-up to measure predicted maximal aerobic power, and semi-structured interviews were conducted to assess the acceptability of using an electric bicycle...
May 8, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29730375/twelve-month-results-from-the-first-in-human-randomized-study-of-the-ranger-paclitaxel-coated-balloon-for-femoropopliteal-treatment
#6
Sabine Steiner, Andrea Willfort-Ehringer, Horst Sievert, Volker Geist, Michael Lichtenberg, Costantino Del Giudice, Antoine Sauguet, Juan Diaz-Cartelle, Claudia Marx, Armin Ströbel, Ingolf Schult, Dierk Scheinert
OBJECTIVES: The authors sought to evaluate the performance of the Ranger paclitaxel-coated balloon versus uncoated balloon angioplasty for femoropopliteal lesions at 12 months. BACKGROUND: Drug-coated balloons (DCBs) are a promising endovascular treatment option for peripheral artery disease of the femoropopliteal segment, and each unique device requires dedicated clinical study. METHODS: The prospective, randomized RANGER SFA (Comparison of the Ranger™ Paclitaxel-Coated PTA Balloon Catheter and Uncoated PTA Balloons in Femoropopliteal Arteries) study (NCT02013193) enrolled 105 patients with symptomatic lower limb ischemia (Rutherford category 2 to 4) and stenotic lesions in the nonstented femoropopliteal segment at 10 European centers...
April 27, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29713383/collective-feature-selection-to-identify-crucial-epistatic-variants
#7
Shefali S Verma, Anastasia Lucas, Xinyuan Zhang, Yogasudha Veturi, Scott Dudek, Binglan Li, Ruowang Li, Ryan Urbanowicz, Jason H Moore, Dokyoon Kim, Marylyn D Ritchie
Background: Machine learning methods have gained popularity and practicality in identifying linear and non-linear effects of variants associated with complex disease/traits. Detection of epistatic interactions still remains a challenge due to the large number of features and relatively small sample size as input, thus leading to the so-called "short fat data" problem. The efficiency of machine learning methods can be increased by limiting the number of input features. Thus, it is very important to perform variable selection before searching for epistasis...
2018: BioData Mining
https://www.readbyqxmd.com/read/29697437/routine-use-of-adjunctive-p16-immunohistochemistry-improves-diagnostic-agreement-of-cervical-biopsy-interpretation-results-from-the-certain-study
#8
Mark H Stoler, Thomas C Wright, Alex Ferenczy, James Ranger-Moore, Qijun Fang, Monesh Kapadia, Ruediger Ridder
The diagnosis of squamous intraepithelial lesions in cervical tissue specimens is subject to substantial variability. Adjunctive immunohistochemical (IHC) staining for p16 has been shown to add objective biomarker information to morphologic interpretation of hematoxylin and eosin (H&E)-stained tissues. In the CERvical Tissue AdjunctIve aNalysis (CERTAIN) study, we systematically analyzed the impact of adjunctive p16 IHC on the accuracy (agreement with reference pathology results) of diagnosing cervical intraepithelial neoplasia of grade 2 or worse (CIN2+) in the United States...
April 24, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29691616/lars-synthetic-ligaments-for-the-acute-management-of-111-acute-knee-dislocations-effective-surgical-treatment-for-most-ligaments
#9
Pierre Ranger, Andréa Senay, Geneviève Rochette Gratton, Marc Lacelle, Josée Delisle
PURPOSE: The purpose of this study was to describe the longitudinal outcomes of acute repair and augmentation for the reconstruction of dislocated knees, using LARS synthetic ligaments. METHODS: Patients with a knee dislocation surgically treated using LARS synthetic ligament augmentation, with a minimum follow-up of 24 months, were enrolled between 1996 and 2014. Range of motion, Lachman, pivot shift, posterior drawer, step off sign, valgus, varus, KT-1000 arthrometer, Telos technique, IKDC, Lysholm, Tegner, and Meyers scores were obtained every 2 years up to 10 years...
April 24, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29688310/ranger-dtl-2-0-rigorous-reconstruction-of-gene-family-evolution-by-duplication-transfer-and-loss
#10
Mukul S Bansal, Manolis Kellis, Misagh Kordi, Soumya Kundu
Summary: RANGER-DTL 2.0 is a software program for inferring gene family evolution using Duplication-Transfer-Loss reconciliation. This new software is highly scalable and easy to use, and offers many new features not currently available in any other reconciliation program. RANGER-DTL 2.0 has a particular focus on reconciliation accuracy and can account for many sources of reconciliation uncertainty including uncertain gene tree rooting, gene tree topological uncertainty, multiple optimal reconciliations, and alternative event cost assignments...
April 24, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29619118/epigenetic-modifications-in-kdm-lysine-demethylases-associate-with-survival-of-early-stage-nsclc
#11
Yongyue Wei, Junya Liang, Ruyang Zhang, Yichen Guo, Sipeng Shen, Li Su, Xihong Lin, Sebastian Moran, Åslaug Helland, Maria M Bjaanæs, Anna Karlsson, Maria Planck, Manel Esteller, Thomas Fleischer, Johan Staaf, Yang Zhao, Feng Chen, David C Christiani
Background: KDM lysine demethylase family members are related to lung cancer clinical outcomes and are potential biomarkers for chemotherapeutics. However, little is known about epigenetic alterations in KDM genes and their roles in lung cancer survival. Methods: Tumor tissue samples of 1230 early-stage non-small cell lung cancer (NSCLC) patients were collected from the five independent cohorts. The 393 methylation sites in KDM genes were extracted from epigenome-wide datasets and analyzed by weighted random forest (Ranger) in discovery phase and validation dataset, respectively...
2018: Clinical Epigenetics
https://www.readbyqxmd.com/read/29550786/quantification-of-energy-expenditure-of-military-loaded-runs-what-is-the-performance-of-laboratory-based-equations-when-applied-to-the-field-environment
#12
Alessandro L Colosio, S Pogliaghi
INTRODUCTION: Performance during army loaded runs provides a synthetic indicator of a soldier's capacity to move while carrying loads and thereby remain able to execute a mission. The aim of this study was to estimate and compare the energy expenditure (EE) of army loaded runs, conducted in a field environment using laboratory-based equations and HR index (HRindex ). METHODS: 45 Ranger recruits had HR monitored during three loaded runs (10, 15 and 20 km) in full military equipment in the field environment...
March 17, 2018: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29549875/soil-uranium-concentration-at-ranger-uranium-mine-land-application-areas-drives-changes-in-the-bacterial-community
#13
Saqib Mumtaz, Claire Streten, David L Parry, Keith A McGuinness, Ping Lu, Karen S Gibb
Soil microorganisms may respond to metal stress by a shift in the microbial community from metal sensitive to metal resistant microorganisms. We assessed the bacterial community from low (2-20 mg kg-1 ), medium (200-400 mg kg-1 ), high (500-900 mg kg-1 ) and very high (>900 mg kg-1 ) uranium soils at Ranger Uranium Mine in northern Australia through pyrosequencing. Proteobacteria (28.85%) was the most abundant phylum at these sites, followed by Actinobacteria (9.31%), Acidobacteria (7.33%), Verrucomicrobia (2...
September 2018: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29548031/cross-sectional-area-of-the-achilles-tendon-in-a-cohort-of-elite-military-warriors-using-standard-ultrasound-techniques
#14
Kevin D Martin, Jeffrey Wake, Laura Dawson, J Preston Van Buren
Background: The prevalence of Achilles tendon (AT) pathology is common and can result in disability. Understanding normal AT properties can improve our ability to prevent AT injuries. We examined the cross-sectional area of the AT at multiple levels in an asymptomatic population of Army Rangers. Methods: This is a prospective cohort study composed of 41 voluntarily recruited United States Army Rangers deployed in a combat theater. All subjects were members of the Ranger Regiment participating in more than 20 h of intense bipedal non-sport weekly training with no history of AT pathology...
March 14, 2018: Military Medicine
https://www.readbyqxmd.com/read/29533542/exposure-to-hepatitis-e-virus-hepatitis-a-virus-and-borrelia-spp-infections-in-forest-rangers-from-a-single-forest-district-in-western-poland
#15
Maciej Bura, Alicja Bukowska, Michał Michalak, Aleksandra Bura, Mariusz J Nawrocki, Marek Karczewski, Iwona Mozer-Lisewska
BACKGROUND: Hepatitis E virus (HEV) infection is an emerging problem in developed countries. At least 2 zoonotic genotypes of the virus (HEV-3 and HEV-4) infect human beings. There are some data suggesting that forest rangers (FRs) can be at a higher risk of contact with HEV. OBJECTIVES: The aim of this study was to assess the prevalence of HEV exposure markers in FRs from a single forest district in Greater Poland in relation to anti-HAV (hepatitis A virus) IgG, and anti-Borrelia spp...
March 13, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29483041/a-dosimetric-comparison-of-breast-radiotherapy-techniques-to-treat-locoregional-lymph-nodes-including-the-internal-mammary-chain
#16
A Ranger, A Dunlop, K Hutchinson, H Convery, M K Maclennan, H Chantler, N Twyman, C Rose, D McQuaid, R A Amos, C Griffin, N M deSouza, E Donovan, E Harris, C E Coles, A Kirby
AIMS: Radiotherapy target volumes in early breast cancer treatment increasingly include the internal mammary chain (IMC). In order to maximise survival benefits of IMC radiotherapy, doses to the heart and lung should be minimised. This dosimetry study compared the ability of three-dimensional conformal radiotherapy, arc therapy and proton beam therapy (PBT) techniques with and without breath-hold to achieve target volume constraints while minimising dose to organs at risk (OARs). MATERIALS AND METHODS: In 14 patients' datasets, seven IMC radiotherapy techniques were compared: wide tangent (WT) three-dimensional conformal radiotherapy, volumetric-modulated arc therapy (VMAT) and PBT, each in voluntary deep inspiratory breath-hold (vDIBH) and free breathing (FB), and tomotherapy in FB only...
June 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29444100/super-ranging-a-new-ranging-strategy-in-european-badgers
#17
Aoibheann Gaughran, David J Kelly, Teresa MacWhite, Enda Mullen, Peter Maher, Margaret Good, Nicola M Marples
We monitored the ranging of a wild European badger (Meles meles) population over 7 years using GPS tracking collars. Badger range sizes varied seasonally and reached their maximum in June, July and August. We analysed the summer ranging behaviour, using 83 home range estimates from 48 individuals over 6974 collar-nights. We found that while most adult badgers (males and females) remained within their own traditional social group boundaries, several male badgers (on average 22%) regularly ranged beyond these traditional boundaries...
2018: PloS One
https://www.readbyqxmd.com/read/29395471/multitechnique-characterization-of-conventional-and-experimental-ag-based-brazing-alloys-for-orthodontic-applications
#18
Argyro Ntasi, Youssef S Al Jabbari, Nick Silikas, Theodore Eliades, Spiros Zinelis
OBJECTIVES: To characterize the microstructure, mechanical properties, ionic release and tarnish resistance of conventional and experimental Ag-based soldering alloys for orthodontic applications. METHODS: Disk shaped specimens were prepared from four commercial Ag based soldering alloys [Dentaurum Universal Silver Solder (DEN), Orthodontic Solders (LEO), Ortho Dental Universal Solder (NOB), and Silver Solder (ORT)] and four experimental alloys Ag12Ga, Ag10Ga5Sn, Ag20In and Ag7Sn...
March 2018: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29373836/patients-perceived-needs-of-health-care-providers-for-low-back-pain-management-a-systematic-scoping-review
#19
REVIEW
Louisa Chou, Tom A Ranger, Waruna Peiris, Flavia M Cicuttini, Donna M Urquhart, Kaye Sullivan, K L M D Seneviwickrama, Andrew M Briggs, Anita E Wluka
BACKGROUND CONTEXT: Optimal management of low back pain (LBP) involves patients' active participation in care, facilitated by positive interactions with their health care provider(s) (HCP). An understanding of patients' perceived needs regarding their HCP is, therefore, necessary to achieve such outcomes. Therefore, the aim of the present study is to review the existing literature regarding patients' perceived needs of HCP managing LBP. METHODS: A systematic scoping review of publications in MEDLINE, EMBASE, CINAHL, and PsycINFO (1990-2016) was performed...
April 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29359456/the-nature-and-consequences-of-essentialist-beliefs-about-race-in-early-childhood
#20
Tara M Mandalaywala, Gabrielle Ranger-Murdock, David M Amodio, Marjorie Rhodes
It is widely believed that race divides the world into biologically distinct kinds of people-an essentialist belief inconsistent with reality. Essentialist views of race have been described as early emerging, but this study found that young children (n = 203, Mage  = 5.45) hold only the more limited belief that the physical feature of skin color is inherited and stable. Overall, children rejected the causal essentialist view that behavioral and psychological characteristics are constrained by an inherited racial essence...
January 23, 2018: Child Development
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