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https://www.readbyqxmd.com/read/28812046/extra-virgin-olive-oil-ameliorates-cognition-and-neuropathology-of-the-3xtg-mice-role-of-autophagy
#1
Elisabetta Lauretti, Luigi Iuliano, Domenico Praticò
OBJECTIVE: Consumption of extra virgin olive oil (EVOO), a major component of the Mediterranean diet, has been associated with reduced incidence of Alzheimer's disease (AD). However, the mechanisms involved in this protective action remain to be fully elucidated. METHODS: Herein, we investigated the effect of daily consumption of EVOO on the AD-like phenotype of a mouse mode of the disease with plaques and tangles. RESULTS: Triple transgenic mice (3xTg) received either regular chow or a chow diet supplemented with EVOO starting at 6 months of age for 6 months, then assessed for the effect of the diet on the AD-like neuropathology and behavioral changes...
August 2017: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/28806974/association-of-plasma-fatty-acid-alteration-with-the-severity-of-coronary-artery-disease-lesions-in-tunisian-patients
#2
Samia Hadj Ahmed, Nadia Kaoubaa, Wafa Kharroubi, Amira Zarrouk, Mohamed Fadhel Najjar, Fathi Batbout, Habib Gamra, Gerard Lizard, Mohamed Hammami
BACKGROUND: Some factors related to diet are known to be involved in the progression of atherosclerosis in humans. METHODS: The relationship between plasma fatty acid (FA) levels and the severity of coronary artery disease (CAD), evaluated by Gensini score (GS), was investigated in CAD Tunisian patients compared to controls. Lipid profiles were analyzed, GS was calculated in CAD and non-CAD patients and compared to controls. RESULTS: CAD patients showed an alteration of conventional lipid parameters...
August 14, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28806487/gut-microbiome-response-to-short-term-dietary-interventions-in-reactive-hypoglycemia-subjects
#3
Sara Quercia, Silvia Turroni, Jessica Fiori, Matteo Soverini, Simone Rampelli, Elena Biagi, Andrea Castagnetti, Clarissa Consolandi, Marco Severgnini, Mario Pianesi, Francesco Fallucca, Paolo Pozzilli, Patrizia Brigidi, Marco Candela
BACKGROUND: Reactive hypoglycemia (RH) is a metabolic disorder that provokes severe hypoglycemic episodes after meal. Over recent years, the gut microbiota (GM) has been recognized as potential target for the control of metabolic diseases, and the possibility to correct GM dysbioses through diet, favoring the recovery of metabolic homeostasis, has been considered. METHODS: We investigate the impact of two short-term (3-day) nutritional interventions, based on the macrobiotic Ma-Pi 2 diet and a control Mediterranean diet, on the structure and functionality of the GM in 12 patients affected by RH...
August 14, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/28805669/effect-of-mediterranean-diet-and-antioxidant-formulation-in-non-alcoholic-fatty-liver-disease-a-randomized-study
#4
Ludovico Abenavoli, Marta Greco, Natasa Milic, Francesca Accattato, Daniela Foti, Elio Gulletta, Francesco Luzza
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide, characterized by liver fatty acid accumulation and fibrosis, not due to excessive alcohol consumption. Notably, nutritional habits have been reported to be implicated in the onset and severity of the hepatic damage, while the Mediterranean diet has shown beneficial effects on NAFLD. Free radicals and oxidative stress were suggested to be involved in the pathogenesis and progression of NAFLD, and several data highlighted the efficacy of antioxidant supplementation in its treatment...
August 12, 2017: Nutrients
https://www.readbyqxmd.com/read/28803596/associations-of-baltic-sea-and-mediterranean-dietary-patterns-with-bone-mineral-density-in-elderly-women
#5
Arja T Erkkilä, Homa Sadeghi, Masoud Isanejad, Jaakko Mursu, Marjo Tuppurainen, Heikki Kröger
OBJECTIVE: Dietary quality in relation to bone health has been analysed in relatively few studies. The current study aimed to assess the association of the Baltic Sea diet (BSD) and the Mediterranean diet (MD) with bone mineral density (BMD) among elderly women. DESIGN: Lumbar, femoral and total body BMD were measured by dual-energy X-ray absorptiometry at baseline and year 3. Dietary intake was measured by 3 d food record at baseline. BSD and MD scores were calculated from food and alcohol consumption and nutrient intake...
August 14, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28802282/evolution-of-mediterranean-diets-and-cuisine-concepts-and-definitions
#6
Sue Radd-Vagenas, Antigone Kouris-Blazos, Maria Fiatarone Singh, Victoria M Flood
BACKGROUND AND OBJECTIVES: The Mediterranean diet has been demonstrated to provide a range of health benefits in observational and clinical trials and adopted by various dietary guidelines. However, a broad range of definitions exist impeding synthesis across trials. This review aims to provide a historical description of Mediterranean diets, from the ancient to the modern, to inform future educational and diet index tool development representing the 'traditional' Mediterranean diet. METHODS AND STUDY DESIGN: Nine databases were searched from inception to July 2015 to identify papers defining the Mediterranean diet...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28800091/inverse-associations-between-a-locally-validated-mediterranean-diet-index-overweight-obesity-and-metabolic-syndrome-in-chilean-adults
#7
Guadalupe Echeverría, Emma E McGee, Inés Urquiaga, Paulina Jiménez, Sonia D'Acuña, Luis Villarroel, Nicolás Velasco, Federico Leighton, Attilio Rigotti
Obesity and metabolic syndrome (MetS) are key risk factors for chronic disease. Dietary patterns are critical in the incidence and persistence of obesity and MetS, yet there is few data linking diet to obesity and MetS in Chile. Our objective was to use a locally validated diet index to evaluate adherence to a Mediterranean dietary pattern and its correlations with overweight/obesity (OW/O) and MetS prevalence in Chilean adults. We conducted a nationwide, cross-sectional online survey of Chilean adults with complete self-reported diet and body mass index data (n = 24,882)...
August 11, 2017: Nutrients
https://www.readbyqxmd.com/read/28799803/nutrition-inflammation-and-liver-spleen-axis
#8
Luigi Barrea, Carolina Di Somma, Giovanna Muscogiuri, Giovanni Tarantino, Gian Carlo Tenore, Francesco Orio, Annamaria Colao, Silvia Savastano
Chronic low-grade systemic inflammation represents a mechanism common to many diseases linked to atherosclerosis-related pathways. There is a growing body of evidence indicating that the combination of food quantity and quality along with genetic susceptibility are able to induce the aberrant activation of innate immune signalling, which initially contributes to chronic low-grade inflammation. Liver represents the central player to inflammatory response. Dietary/metabolic factors contribute to the pathogenesis of Non-alcoholic Fatty Liver Disease (NAFLD), the main causes of liver disease in the Western world...
August 11, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28789729/adherence-to-the-mediterranean-diet-is-associated-with-the-gut-microbiota-pattern-and-gastrointestinal-characteristics-in-an-adult-population
#9
Evdokia K Mitsou, Aimilia Kakali, Smaragdi Antonopoulou, Konstantinos C Mountzouris, Mary Yannakoulia, Demosthenes B Panagiotakos, Adamantini Kyriacou
This study aimed to explore the potential associations of adherence to the Mediterranean diet with gut microbiota characteristics and gastrointestinal symptomatology in an adult population. Other long-term dietary habits (e.g. consumption of snacks and junk food or stimulant intake) were also evaluated in terms of the gut microbiota profile. Participants (n 120) underwent anthropometric, dietary, physical activity and lifestyle evaluation. Adherence to the Mediterranean diet was assessed using a Mediterranean diet score, the MedDietScore, and subjects were classified into three tertiles according to individual adherence scoring...
June 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28783384/clinical-physical-physiological-and-dietary-patterns-of-obese-and-sedentary-adults-with-primary-hypertension-characterized-by-sex-and-cardiorespiratory-fitness-exerdiet-hta-study
#10
Ilargi Gorostegi-Anduaga, Pablo Corres, Borja Jurio-Iriarte, Aitor Martínez-Aguirre, Javier Pérez-Asenjo, Gualberto R Aispuru, Lide Arenaza, Estibaliz Romaratezabala, Iñaki Arratibel-Imaz, Iñigo Mujika, Silvia Francisco-Terreros, Sara Maldonado-Martín
The main purpose of this study was to determine some key physical, physiological, clinical, and nutritional markers of health status in obese and sedentary adults (54.0 ± 8.1 years, 141 men and 68 women) with primary hypertension (HTN) characterized by sex and cardiorespiratory fitness (CRF) level. The studied population showed a high cardiovascular risk (CVR) profile including metabolically abnormal obese, with poor CRF level (22.5 ± 5.6 mL·kg(-1)·min(-1)), exercise-induced HTN (Systolic Blood Pressure>210 mmHg in men and >190 mmHg in women at the end of the exercise test) and with non-healthy adherence to dietary pattern (Dietary Approaches to Stop Hypertension, 46...
August 7, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28777292/influence-of-a-virgin-olive-oil-versus-butter-plus-cholesterol-enriched-diet-on-testicular-enzymatic-activities-in-adult-male-rats
#11
Germán Domínguez-Vías, Ana Belén Segarra, Magdalena Martínez-Cañamero, Manuel Ramírez-Sánchez, Isabel Prieto
The aim of the present work was to improve our knowledge on the mechanisms underlying the beneficial or deleterious effects on testicular function of the so-called Mediterranean and Western diet by analyzing glutamyl aminopeptidase (GluAP), gamma glutamyl transpeptidase (GGT) and dipeptidyl peptidase IV (DPP IV) activities in testis, as enzymes involved in testicular function. Male Wistar rats (6 months old) were fed for 24 weeks with three different diets: standard (S), an S diet supplemented with virgin-olive-oil (20%) (VOO), or a S diet enriched with butter (20%) plus cholesterol (0...
August 4, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28763509/mediterranean-diet-and-cognitive-health-initial-results-from-the-hellenic-longitudinal-investigation-of-ageing-and-diet
#12
Costas A Anastasiou, Mary Yannakoulia, Mary H Kosmidis, Efthimios Dardiotis, Giorgos M Hadjigeorgiou, Paraskevi Sakka, Xanthi Arampatzi, Anastasia Bougea, Ioannis Labropoulos, Nikolaos Scarmeas
BACKGROUND: The Mediterranean dietary pattern has been associated with a decreased risk of many degenerative diseases and cognitive function in particular; however, relevant information from Mediterranean regions, where the prototype Mediterranean diet is typically adhered to, have been very limited. Additionally, predefined Mediterranean diet (MeDi) scores with use of a priori cut-offs have been used very rarely, limiting comparisons between different populations and thus external validity of the associations...
2017: PloS One
https://www.readbyqxmd.com/read/28754004/synergistic-interplay-between-curcumin-and-polyphenol-rich-foods-in-the-mediterranean-diet-therapeutic-prospects-for-neurofibromatosis-1-patients
#13
Teresa Esposito, Carla Schettino, Paola Polverino, Salvatore Allocca, Laura Adelfi, Alessandra D'Amico, Guglielmo Capaldo, Bruno Varriale, Anna Di Salle, Gianfranco Peluso, Giuseppe Sorrentino, Giacomo Lus, Simone Sampaolo, Giuseppe Di Iorio, Mariarosa Anna Beatrice Melone
Neurofibromas are the hallmark lesions in Neurofibromatosis 1 (NF1); these tumors are classified as cutaneous, subcutaneous and plexiform. In contrast to cutaneous and subcutaneous neurofibromas, plexiform neurofibromas can grow quickly and progress to malignancy. Curcumin, a turmeric-derived polyphenol, has been shown to interact with several molecular targets implicated in carcinogenesis. Here, we describe the impact of different dietary patterns, namely Mediterranean diet (MedDiet) compared to the Western diet (WesDiet), both with or without curcumin, on NF1 patients' health...
July 21, 2017: Nutrients
https://www.readbyqxmd.com/read/28748997/-role-of-mediterranean-diet-on-the-prevention-of-alzheimer-disease
#14
Arnoldo Miranda, Carolina Gómez-Gaete, Sigrid Mennickent
Type 2 diabetes and obesity are possible risk factors for Alzheimer’s disease and these can be modified by physical activity and changes in dietary patterns, such as switching to a Mediterranean diet. This diet includes fruits, vegetables, olive oil, fish and moderate wine intake. These foods provide vitamins, polyphenols and unsaturated fatty acids. This diet should be able to reduce oxidative stress. The inflammatory response is also reduced by unsaturated fatty acids, resulting in a lower expression and a lower production of pro-inflammatory cytokines...
April 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28741614/diet-and-risk-of-cholecystectomy-a-prospective-study-based-on-the-french-e3n-cohort
#15
Amélie Barré, Gaëlle Gusto, Claire Cadeau, Franck Carbonnel, Marie-Christine Boutron-Ruault
OBJECTIVES: This study aimed to examine the relationship between diet and cholecystectomy risk, using three approaches, in a large French cohort. METHODS: In a prospective cohort study in French women who completed a food-frequency questionnaire at baseline, we analyzed diet with three approaches: food groups, dietary patterns obtained by factor analysis, and the Mediterranean diet score. The primary outcome was cholecystectomy. We used Cox proportional hazards regression to assess the relationship between diet and cholecystectomy risk, adjusting for the main potential confounders...
July 25, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28741383/adherence-to-mediterranean-diet-and-metabolic-syndrome-in-brca-mutation-carriers
#16
Eleonora Bruno, Siranoush Manoukian, Elisabetta Venturelli, Andreina Oliverio, Francesca Rovera, Giovanna Iula, Daniele Morelli, Bernard Peissel, Jacopo Azzolini, Eliana Roveda, Patrizia Pasanisi
BACKGROUND: Insulin resistance is associated with higher breast cancer (BC) penetrance in BRCA mutation carriers. Metabolic syndrome (MetS), an insulin resistance syndrome, can be reversed by adhering to the Mediterranean diet (MedDiet). In a dietary intervention trial on BRCA mutation carriers, we evaluated adherence to the MedDiet, and the association with the MetS, by analyzing data from the Mediterranean Diet Adherence Screener (MEDAS). METHODS: BRCA mutation carriers, with or without BC, aged 18 to 70 years, were eligible for the trial...
July 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28736911/observational-study-of-adherence-to-a-traditional-mediterranean-diet-sociocultural-characteristics-and-cardiovascular-disease-risk-factors-of-older-greek-australians-from-mediterranean-islands-medis-australia-study-protocol-and-rationale
#17
Antonia Thodis, Catherine Itsiopoulos, Antigone Kouris-Blazos, Laima Brazionis, Stefanos Tyrovolas, Evangelos Polychronopoulos, Demosthenes B Panagiotakos
AIM: To describe the study protocol of the MEDiterranean ISlands-Australia (MEDIS-Australia) Study modelled on the MEDIS Study conducted in Greece. The present study aims to explore adherence to the traditional Mediterranean diet pattern, determine enablers and barriers to adherence, explore the definition of Greek cuisine, and associations between adherence to the diet pattern and risk factors for cardiovascular disease (CVD) and metabolic syndrome in older Greek Australians originally from Greek islands and Cyprus...
July 24, 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28734553/dietary-inflammatory-index-and-liver-status-in-subjects-with-different-adiposity-levels-within-the-predimed-trial
#18
Irene Cantero, Itziar Abete, Nancy Babio, Fernando Arós, Dolores Corella, Ramón Estruch, Montse Fitó, James R Hebert, M Ángel Martínez-González, Xavier Pintó, M Puy Portillo, Miguel Ruiz-Canela, Nitin Shivappa, Julia Wärnberg, Enrique Gómez-Gracia, J Antoni Tur, Jordi Salas-Salvadó, M Angeles Zulet, J Alfredo Martínez
BACKGROUND & AIMS: To assess the possible association between a validated Dietary Inflammatory Index (DII) and specific dietary components with suitable non-invasive markers of liver status in overweight and obese subjects within the PREDIMED study. METHODS: A cross-sectional study encompassing 794 randomized overweight and obese participants (mean ± SD age: 67.0 ± 5.0 y, 55% females) from the PREDIMED (PREvención con DIeta MEDiterránea) trial was conducted...
July 6, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28731489/sexual-health-adherence-to-mediterranean-diet-body-weight-physical-activity-and-mental-state-factors-correlated-to-each-other
#19
Pier A Della Camera, Simone Morselli, Gianmartin Cito, Giovanni Tasso, Andrea Cocci, Nicola Laruccia, Fabrizio Travaglini, Dario Del Fabbro, Antonio R Mottola, Mauro Gacci, Sergio Serni, Marco Carini, Alessandro Natali
INTRODUCTION: Mediterranean diet has shown a protective role against cardiovascular disease, diabetes, cancer onset, microvascular damage and dementia in many trials. Our purpose is the assessment of a correlation between physical activity, Mediterranean diet, body mass index (BMI), depression and erection disorder (ED). METHODS: After having signed disclaimer to the study participation, we administered the IIEF 15 questionnaire (International Index of Erectil Function), the Hamilton questionnaire for major depression, the Med-Diet Questionnaire, the Ipaq Questionnaire (International Index of Physical Activity) to 245 patients and calculated the BMI...
July 14, 2017: Urologia
https://www.readbyqxmd.com/read/28731131/assessment-of-the-antioxidant-activity-of-an-olive-oil-total-polyphenolic-fraction-and-hydroxytyrosol-from-a-greek-olea%C3%A2-europea-variety-in-endothelial-cells-and-myoblasts
#20
Paraskevi Kouka, Alexandros Priftis, Dimitrios Stagos, Apostolis Angelis, Panagiotis Stathopoulos, Nikos Xinos, Alexios-Léandros Skaltsounis, Charalampos Mamoulakis, Aristides M Tsatsakis, Demetrios A Spandidos, Demetrios Kouretas
Olive oil (OO) constitutes the basis of the Mediterranean diet, and it seems that its biophenols, such as hydroxytyrosol (HT) may scavenge free radicals, attracting distinct attention due to their beneficial effects in many pathological conditions, such as cancer. To the best of our knowedge, this is the first study in which the functional properties of an OO total polyphenolic fraction (TPF) and pure HT were examined in order to determine their antioxidant effects at a cellular level in endothelial cells and myoblasts...
September 2017: International Journal of Molecular Medicine
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