keyword
MENU ▼
Read by QxMD icon Read
search

Swollen joint

keyword
https://www.readbyqxmd.com/read/27896842/il-12b-gene-polymorphisms-and-il-12-p70-serum-levels-among-patients-with-rheumatoid-arthritis
#1
A Paradowska-Gorycka, A Sowinska, B Stypińska, E Haladyj, A Pawlik, K Romanowska-Próchnicka, M Olesinska
OBJECTIVES: Rheumatoid arthritis (RA) is one of the autoimmune diseases, where different polymorphisms in cytokine genes play a pathogenic role. IL-12 is now recognized as a critical cytokine in terms of regulating the balance between Th1 and Th2 cells. We investigated the role of single-nucleotide polymorphisms (SNPs) (rs3212227 (A/C) and rs17860508 (CTCTAA/GC)) of the IL-12B gene in the genetic susceptibility to RA and in the severity of the disease. METHODS: Six hundred and thirty four Caucasian RA patients and 341 healthy matched controls were studied using PCR-RFLP method and High-resolution melting analysis...
November 29, 2016: Scandinavian Journal of Immunology
https://www.readbyqxmd.com/read/27882446/impact-of-the-size-and-number-of-swollen-joints-on-serum-c-reactive-protein-level-and-erythrocyte-sedimentation-rate-in-rheumatoid-arthritis-a-cross-sectional-study-in-japan
#2
Kota Shimada, Akiko Komiya, Naoto Yokogawa, Jinju Nishino, Shoji Sugii, Shigeto Tohma
No studies have yet reported the influence of swelling in individual joints on serum C-reactive protein and erythrocyte sedimentation rate. To examine this association, we used data from the NinJa registry, the largest registry of rheumatoid arthritis patients in Japan. Sixty-six palpable joints were categorized by size into three groups (small, medium-sized, and knees) with surface area cutoffs of 10 and 100 cm(2). Of 10,720 cases registered in NinJa in 2012, 8444 cases with either no swollen joints or swelling limited to one joint-size category were analyzed...
November 23, 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27870649/the-reliability-of-disease-activity-score-in-28-joints-c-reactive-protein-might-be-overestimated-in-a-subgroup-of-rheumatoid-arthritis-patients-when-the-score-is-solely-based-on-subjective-parameters-a-cross-sectional-exploratory-study
#3
Inger Marie Jensen Hansen, Rikke Asmussen Andreasen, Mark Nam van Bui Hansen, Amir Emamifar
BACKGROUND: Disease Activity Score in 28 Joints (DAS28) is a scoring system to evaluate disease activity and treatment response in rheumatoid arthritis (RA). A DAS28 score of greater than 3.2 is a well-described limit for treatment intensification; however, the reliability of DAS28 might be overestimated. OBJECTIVE: The aim of this study was to evaluate the reliability of DAS28 in RA, especially focusing on a subgroup of patients with a DAS28 score of greater than 3...
November 19, 2016: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/27866179/tripterygium-glycosides-for-treating-late-onset-rheumatoid-arthritis-a-systematic-review-and-meta-analysis
#4
Xiao Xu, Quan Jin Li, Sha Xia, Miao Miao Wang, Wei Ji
Context • Older- or late-onset rheumatoid arthritis (LORA) is defined as rheumatoid arthritis (RA) with an onset of symptoms at age 60 y or older, which includes a specific clinical course and features. To date, a specific therapeutic treatment for LORA is still a dilemma in modern medicine. Objective • The study aimed to assess the effectiveness and safety of Tripterygium glycosides for treating LORA. Design • Seven databases were searched from their inceptions until June 2015. The research team included randomized, controlled trials (RCTs) in which Tripterygium glycosides were employed, either alone or as an adjuvant treatment with disease-modifying antirheumatic drugs (DMARDs), in patients with LORA...
November 2016: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/27858838/a-case-report-of-children-s-divergent-dislocation-of-the-elbow-and-review-of-literature
#5
Yongtao Wu, Hai Jiang, Wusheng Miao
BACKGROUND: The divergent dislocation of the elbow is not common in children, and the imaging is difficult and challenging. This often leads to misdiagnosis or inappropriate treatment. The literature has reported a total of 19 cases currently. METHODS: A 10-year-old girl with divergent dislocation of the elbow was admitted in our department in November 2013. When playing basketball, her right elbow was injured on the concrete floor. After injury, her right elbow joint became severely swollen, with obvious deformity...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27857821/carotid-artery-atherosclerosis-in-patients-with-active-rheumatoid-arthritis-predictors-of-plaque-occurrence-and-progression-over-24-weeks
#6
Janet E Pope, Tatiana Nevskaya, Lillian Barra, Grace Parraga
INTRODUCTION: This study evaluated the prevalence and progression of subclinical carotid artery atherosclerosis in active rheumatoid arthritis (RA). METHODS: Carotid arteries of RA patients were scanned using 3D ultrasound at baseline and 24 weeks for total plaque area, vessel wall volume, and intima-media thickness (IMT), as well as arterial stiffness measured using pulse wave velocity. Variables related to inflammation, lipids and cardiovascular (CV) risk were assessed for associations with plaque progression...
2016: Open Rheumatology Journal
https://www.readbyqxmd.com/read/27851825/severity-and-diurnal-improvement-of-morning-stiffness-independently-associate-with-tenosynovitis-in-patients-with-rheumatoid-arthritis
#7
Yoshihisa Kobayashi, Kei Ikeda, Takayuki Nakamura, Mieko Yamagata, Takuya Nakazawa, Shigeru Tanaka, Shunsuke Furuta, Takeshi Umibe, Hiroshi Nakajima
BACKGROUND AND OBJECTIVES: Although morning stiffness has long been recognized as a characteristic feature of rheumatoid arthritis (RA), it is no more included in the 2010 ACR/EULAR Classification Criteria or in the current major instruments for evaluating disease activity of RA. In this cross-sectional study, we aimed to determine the independent value and the optimal measurement of morning stiffness by clarifying the associations between morning stiffness and synovial inflammation. PATIENTS AND METHODS: We enrolled 76 consecutive RA patients who underwent musculoskeletal ultrasound examination and agreed to participate in the study...
2016: PloS One
https://www.readbyqxmd.com/read/27843577/age-affects-joint-space-narrowing-in-patients-with-early-active-rheumatoid-arthritis
#8
X M E Matthijssen, G Akdemir, I M Markusse, T Stijnen, N Riyazi, K H Han, C Bijkerk, P J S M Kerstens, W F Lems, T W J Huizinga, C F Allaart
BACKGROUND: Joint space narrowing (JSN) in rheumatoid arthritis (RA) may be a manifestation of (primary) osteoarthritis becoming more prominent with age. We investigated the severity and predictors of JSN progression among different age groups. METHODS: 10-year follow-up data of the BeSt study, a randomised controlled treat-to-target trial in early RA were used. Annual X-rays of hands and feet were scored using the Sharp/van der Heijde score (SHS). Subgroups were defined by age at baseline: ≥55, ≥40<55 and <40 years...
2016: RMD Open
https://www.readbyqxmd.com/read/27821943/green-tea-and-exercise-interventions-as-nondrug-remedies-in-geriatric-patients-with-rheumatoid-arthritis
#9
Ahmad H Alghadir, Sami A Gabr, Einas S Al-Eisa
This study aimed to evaluate the effects of green tea and supervised exercise training interventions on improvement of disease activity and bone metabolism markers in rheumatoid arthritis patients. [Subjects and Methods] One-hundred and twenty subjects who had a mean age of (60.7 ± 2.53 years) and had been diagnosed with rheumatoid arthritis at least ten years previously were randomly included in this study. Patients were treated with infliximab, green tea, or a supervised exercise program for six months...
October 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/27813364/magnetic-resonance-detected-myocardial-inflammation-and-fibrosis-in-rheumatoid-arthritis-associations-of-disease-characteristics-and-n-terminal-pro-brain-natriuretic-peptide-levels
#10
Hitomi Kobayshi, Yasuyuki Kobayashi, Isamu Yokoe, Yosikatsu Akashi, Masami Takei, Jon T Giles
Objective Myocardial dysfunction and heart failure (HF) are increased in rheumatoid arthritis (RA), yet there are few studies of the RA myocardium. Methods RA patients with no known heart disease or risk factors underwent gadolinium-enhanced cardiac magnetic resonance (cMR) imaging. Images were assessed for left-ventricular (LV) structure and functional parameters, and for myocardial late gadolinium enhancement (LGE: an indicator of myocardial fibrosis) and T2-weighted imaging (T2WI: an indicator of active inflammation)...
November 3, 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/27794533/the-psoriatic-arthritis-registry-of-turkey-results-of-a-multicentre-registry-on-1081-patients
#11
Umut Kalyoncu, Özün Bayindir, Mustafa Ferhat Öksüz, Atalay Doğru, Gezmiş Kimyon, Emine Figen Tarhan, Abdulsamet Erden, Şule Yavuz, Meryem Can, Gözde Yıldırım Çetin, Levent Kılıç, Orhan Küçükşahin, Ahmet Omma, Cem Ozisler, Dilek Solmaz, Emine Duygu Ersözlü Bozkirli, Lütfi Akyol, Seval Masatlıoğlu Pehlevan, Esen Kasapoglu Gunal, Fatos Arslan, Barış Yılmazer, Nilgun Atakan, Sibel Zehra Aydın
OBJECTIVE: The aim was to assess the characteristics of PsA, find out how well the disease is controlled in real life, demonstrate the treatments and identify the unmet needs. METHODS: The PsA registry of Turkey is a multicentre Web-based registry established in 2014 and including 32 rheumatology centres. Detailed data regarding demographics for skin and joint disease, disease activity assessments and treatment choices were collected. RESULTS: One thousand and eighty-one patients (64...
October 29, 2016: Rheumatology
https://www.readbyqxmd.com/read/27762199/using-an-electronic-platform-interactively-to-improve-treatment-outcome-in-patients-with-rheumatoid-arthritis-new-developments-from-the-danbio-registry
#12
Merete L Hetland, Niels Steen Krogh, Kim Hørslev-Petersen, Berit Schiøttz-Christensen, Inge Juul Sørensen, Jensen Dorte Vendelbo
OBJECTIVES: Electronic platforms have been developed to help the clinician monitor disease activity in rheumatoid arthritis (RA) to support at treat-to-target strategy. We present an initiative to interactively improve disease control in patients with rheumatoid arthritis. METHODS: In patients who presented with one or more swollen joints AND moderate/high disease activity (i.e. either CDAI≥10.1 and/or DAS-28CRP>3.2, which is automatically calculated in the DANBIO registry), a red alert was shown, which activated a pop-up: "This patient has at least one swollen joint AND either CDAI≥ 10...
September 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27762189/the-disease-activity-score-das-and-the-disease-activity-score-using-28-joint-counts-das28-in-the-management-of-rheumatoid-arthritis
#13
Piet L C M van Riel, Lisanne Renskers
In rheumatoid arthritis (RA), disease activity cannot be measured in all individual patients according to a single variable. The Disease Activity Score (DAS) and the DAS28 have been developed to measure disease activity in RA both in daily clinical practice as well as in clinical trials on a group as well as individual level. The DAS/DAS28 is a continuous measure of RA disease activity that combines information from swollen joints, tender joints, acute phase response and general health. The DAS-based EULAR response criteria were primarily developed to be used in clinical trials...
September 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27757177/evaluation-of-the-anti-inflammatory-effects-of-atorvastatin-on-patients-with-rheumatoid-arthritis-a-randomized-clinical-trial
#14
Zhaleh Shariati Sarabi, Mehran Ghazi Saeidi, Mandana Khodashahi, Ali Etemad Rezaie, Kamila Hashemzadeh, Rozita Khodashahi, Hossein Heidari
BACKGROUND: Rheumatoid arthritis (RA) is a chronic inflammatory joint disorder with unknown etiology. Atorvastatin is a lipid-lowering agent that affects the inflammatory processes. OBJECTIVE: This study aimed to determine the anti-inflammatory effects of atorvastatin on the Disease Activity Index and high-density lipoprotein (HDL) concentrations in RA patients. METHODS: This clinical trial was performed on 38 RA patients, who were referred to the Imam Reza and Ghaem Medical Centers of Mashhad, Iran between 2013 and 2014...
August 2016: Electronic Physician
https://www.readbyqxmd.com/read/27749229/improvement-of-fatigue-in-patients-with-rheumatoid-arthritis-treated-with-biologics-relation-with-sleep-disorders-depression-and-clinical-efficacy-a-prospective-multicentre-study
#15
Marlène Genty, Bernard Combe, Marie Kostine, Elodie Ardouin, Jacques Morel, Cédric Lukas
OBJECTIVES: To assess predictive factors of improvement in related fatigue in rheumatoid arthritis (RA) patients newly receiving biologic therapy, and specifically the influence of the improvement of the quality of sleep. METHODS: We conducted a multicentre prospective study in RA patients requiring initiation or change of biologic therapy. The improvement in fatigue, sleep disorders and depression was assessed respectively by the FACIT fatigue scale, Spiegel scale and Beck Depression Inventory at inclusion (M0) and 3 months (M3) after the beginning of treatment...
October 7, 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27749222/long-term-drug-survival-and-clinical-effectiveness-of-etanercept-treatment-in-patients-with-ankylosing-spondylitis-in-daily-clinical-practice
#16
Suzanne Arends, Elisabeth Brouwer, Monique Efde, Eveline van der Veer, Hendrika Bootsma, Freke Wink, Anneke Spoorenberg
OBJECTIVES: Randomised controlled trials and open-label extension studies have demonstrated the clinical efficacy and safety of tumour necrosis factor-alpha (TNF-α) blocking therapy in pre-selected study patients with ankylosing spondylitis (AS). Our aim was to investigate the 7-year drug survival and clinical effectiveness of etanercept treatment in AS patients in daily clinical practice. METHODS: Consecutive AS patients from the prospective observational GLAS cohort who started etanercept because of active disease were included and evaluated over 7 years according to a fixed protocol...
October 7, 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27748084/performance-of-ultrasound-in-the-diagnosis-of-gout-in-a-multi-center-study-comparison-with-monosodium-urate-crystal-analysis-as-the-gold-standard
#17
Alexis Ogdie, William J Taylor, Tuhina Neogi, Jaap Fransen, Tim L Jansen, H Ralph Schumacher, Worawit Louthrenoo, Janitzia Vazquez-Mellado, Maxim Eliseev, Geraldine McCarthy, Lisa K Stamp, Fernando Perez-Ruiz, Francisca Sivera, Hang-Korng Ea, Martijn Gerritsen, Giovanni Cagnotto, Lorenzo Cavagna, Chingtsai Lin, Yin-Yi Chou, Anne-Kathrin Tausche, Manuella Lima Gomes Ochtrop, Matthijs Janssen, Jiunn-Horng Chen, Ole Slot, Juris Lazovskis, Douglas White, Marco A Cimmino, Till Uhlig, Nicola Dalbeth
OBJECTIVES: To examine the performance of ultrasound for the diagnosis of gout using presence of monosodium urate (MSU) crystals as the gold standard. METHODS: We analyzed data from the Study for Updated Gout Classification Criteria (SUGAR), a large, multi-center observational cross-sectional study of consecutive subjects with at least one swollen joint who conceivably may have gout. All subjects underwent arthrocentesis; cases were subjects with MSU crystal confirmation...
October 16, 2016: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/27738838/elevated-levels-of-serum-mrp8-14-in-ankylosing-spondylitis-associated-with-peripheral-arthritis-and-active-disease
#18
Latika Gupta, Shruti Bhattacharya, Vikas Agarwal, Amita Aggarwal
Monocytes of patients with ankylosing spondylitis (AS) have toll-like receptor 4 (TLR4) overexpression on their monocytes. Myeloid-related protein (MRP) 8/14 protein complexes are calcium-binding proteins, which act as endogenous ligands to TLR4. Thus, we studied the levels of MRP8/14 in adult AS patients. MRP8/14 levels were assessed in 99 adult AS patients satisfying Assessments in Ankylosing Spondylitis International Society 2010 criteria and 71 healthy controls by ELISA. Patient disease parameters like patient and physician global assessment, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), swollen and tender joint count, entheseal count by Maastricht enthesitis index, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) were also recorded...
October 13, 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27736006/body-mass-index-and-response-to-abatacept-in-rheumatoid-arthritis
#19
Anais Gardette, Sébastien Ottaviani, Jérémie Sellam, Francis Berenbaum, Frédéric Lioté, Bruno Fautrel, Elisabeth Palazzo, Alain Meyer, Jean Sibilia, Philippe Dieudé
BACKGROUND: Previous studies suggested that obesity could negatively affect the response to antitumour necrosis factor-α (TNFα) agents in rheumatoid arthritis (RA). However, data are lacking on whether obesity affects the response to abatacept (ABA). We aimed to determine whether body mass index (BMI) affects the response to ABA in RA. MATERIALS AND METHODS: In this multicenter retrospective study, we included RA patients who received ABA. BMI was calculated at the initiation of treatment...
December 2016: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27725536/effects-of-biologic-agents-in-patients-with-rheumatoid-arthritis-and-amyloidosis-treated-with-hemodialysis
#20
Takeshi Kuroda, Naohito Tanabe, Yukiko Nozawa, Hiroe Sato, Takeshi Nakatsue, Daisuke Kobayashi, Yoko Wada, Takako Saeki, Masaaki Nakano, Ichiei Narita
Objective Our objective was to examine the safety and effects of therapy with biologics on the prognosis of rheumatoid arthritis (RA) patients with reactive amyloid A (AA) amyloidosis on hemodialysis (HD). Methods Twenty-eight patients with an established diagnosis of reactive AA amyloidosis participated in the study. The survival was calculated from the date of HD initiation until the time of death, or up to end of June 2015 for the patients who were still alive. HD initiation was according to the program of HD initiation for systemic amyloidosis patients associated with RA...
2016: Internal Medicine
keyword
keyword
114585
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"