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https://www.readbyqxmd.com/read/28809960/metrics-for-comparing-neuronal-tree-shapes-based-on-persistent-homology
#1
Yanjie Li, Dingkang Wang, Giorgio A Ascoli, Partha Mitra, Yusu Wang
As more and more neuroanatomical data are made available through efforts such as NeuroMorpho.Org and FlyCircuit.org, the need to develop computational tools to facilitate automatic knowledge discovery from such large datasets becomes more urgent. One fundamental question is how best to compare neuron structures, for instance to organize and classify large collection of neurons. We aim to develop a flexible yet powerful framework to support comparison and classification of large collection of neuron structures efficiently...
2017: PloS One
https://www.readbyqxmd.com/read/28808438/atsas-2-8-a-comprehensive-data-analysis-suite-for-small-angle-scattering-from-macromolecular-solutions
#2
D Franke, M V Petoukhov, P V Konarev, A Panjkovich, A Tuukkanen, H D T Mertens, A G Kikhney, N R Hajizadeh, J M Franklin, C M Jeffries, D I Svergun
ATSAS is a comprehensive software suite for the analysis of small-angle scattering data from dilute solutions of biological macromolecules or nanoparticles. It contains applications for primary data processing and assessment, ab initio bead modelling, and model validation, as well as methods for the analysis of flexibility and mixtures. In addition, approaches are supported that utilize information from X-ray crystallography, nuclear magnetic resonance spectroscopy or atomistic homology modelling to construct hybrid models based on the scattering data...
August 1, 2017: Journal of Applied Crystallography
https://www.readbyqxmd.com/read/28806971/factors-contributing-to-the-variability-of-a-predictive-score-for-cranial-cruciate-ligament-deficiency-in-labrador-retrievers
#3
Devin P Cunningham, Ayman A Mostafa, Wanda J Gordan-Evans, Randy J Boudrieau, Dominique J Griffon
BACKGROUND: We recently reported that a conformation score derived from the tibial plateau angle (TPA) and the femoral anteversion angle (FAA), best discriminates limbs predisposed to, or affected by cranial cruciate ligament disease (CCLD), from those that are at low risk for CCLD. The specificity and sensitivity of this score were high enough to support further investigations toward its use for large-scale screening of dogs by veterinarians. The next step, which is the objective of the current study, is to determine inter-observer variability of that CCLD score in a large population of Labrador Retrievers...
August 14, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28802416/accuracy-of-valgus-osteotomy-using-dynamic-hip-screw
#4
Sunil G Kulkarni, G S Kulkarni, Sushrut Babhulkar, Milind G Kulkarni, Ruta M Kulkarni
BACKGROUND: Non-union of neck femur is a common but difficult situation to manage especially in young adults. There are two main options of arthroplasty or osteotomy. The aim of this study was to assess the results of intertrochanteric valgus osteotomy in non-union femoral neck fractures. PATIENTS AND METHODS: We present a study of 44 cases of neck femur non-union including untreated fractures, late presentations (more than 3 weeks), treated with compression screw, DHS...
August 2017: Injury
https://www.readbyqxmd.com/read/28790037/a-six-year-retrospective-analysis-of-cut-out-risk-predictors-in-cephalomedullary-nailing-for-pertrochanteric-fractures-can-the-tip-apex-distance-tad-still-be-considered-the-best-parameter
#5
G Caruso, M Bonomo, G Valpiani, G Salvatori, A Gildone, V Lorusso, L Massari
OBJECTIVES: Intramedullary fixation is considered the most stable treatment for pertrochanteric fractures of the proximal femur and cut-out is one of the most frequent mechanical complications. In order to determine the role of clinical variables and radiological parameters in predicting the risk of this complication, we analysed the data pertaining to a group of patients recruited over the course of six years. METHODS: A total of 571 patients were included in this study, which analysed the incidence of cut-out in relation to several clinical variables: age; gender; the AO Foundation and Orthopaedic Trauma Association classification system (AO/OTA); type of nail; cervical-diaphyseal angle; surgical wait times; anti-osteoporotic medication; complete post-operative weight bearing; and radiological parameters (namely the lag-screw position with respect to the femoral head, the Cleveland system, the tip-apex distance (TAD), and the calcar-referenced tip-apex distance (CalTAD))...
August 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28789871/factors-associated-with-discrepancies-between-preoperatively-planned-and-postoperative-alignments-in-patients-undergoing-closed-wedge-high-tibial-osteotomy
#6
Seong Hwan Kim, Du-Hyun Ro, Young-Min Lee, Yool Cho, Sahnghoon Lee, Myung-Chul Lee
BACKGROUND: To evaluate the difference between preoperative plan and postoperative alignment after closed-wedge HTO and determine factors associated with difference. METHODS: This retrospective cohort study included 165 cases with closed-wedge HTO. The following radiographic parameters were measured: mechanical tibiofemoral angle (mTFA), mechanical medial proximal tibial angle (MPTA), joint line convergence angle, mediolateral joint width discrepancy, Kellgren-Lawrence (K-L) grade, and discrepancy between the correction angle in tibia and correction angle in mTFA...
August 5, 2017: Knee
https://www.readbyqxmd.com/read/28776589/oct-glaucoma-staging-system-a-new-method-for-retinal-nerve-fiber-layer-damage-classification-using-spectral-domain-oct
#7
P Brusini
PurposeTo describe a new method, the Optical Coherence Tomography (OCT) Glaucoma Staging System, for classifying retinal nerve fiber layer (RNFL) damage assessed with OCT.Patients and methodsThe OCT Glaucoma Staging System was created based on data obtained from Nidek RS 3000 spectral-domain (sd)-OCT. This system uses the superior and inferior quadrant RNFL thickness values, plotted on an x-y diagram for staging structural damage severity in glaucoma. A non-linear equation and two regression lines describe the boundary lines which separate the different sectors of the diagram...
August 4, 2017: Eye
https://www.readbyqxmd.com/read/28774256/anatomical-variations-of-the-extensor-carpi-ulnaris-groove-a-new-computed-tomography-based-evaluation
#8
Sho Kohyama, Toshikazu Tanaka, Eriko Okano, Ochiai Naoyuki
BACKGROUND: This study aimed to develop a classification that precisely describes the extensor carpi ulnaris (ECU) groove morphology. METHODS: Reconstructed axial plane computed tomography scans of the wrists of 200 patients were reviewed. Three groups of groove shape were created based on the position of the deepest point: deviated to the ulnar side (Type U), in the middle of the groove (Type M), and deviated to the radial side (Type R). Groove depth, width, carrying angle, and radius of the curvature were measured using the Picture Archiving and Communication System in a slice in which the ulnar head was the largest...
September 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28767638/low-bone-mineral-density-is-a-significant-risk-for-proximal-junctional-failure-after-surgical-correction-of-adult-spinal-deformity-a-propensity-score-matched-analysis
#9
Mitsuru Yagi, Nobuyuki Fujita, Osahiko Tsuji, Narihito Nagoshi, Takashi Asazuma, Ken Ishii, Masaya Nakamura, Morio Matsumoto, Kota Watanabe
STUDY DESIGN: A propensity-matched comparison of risk factors for proximal junctional failure (PJF), which is a symptomatic proximal junctional kyphosis developing after corrective surgery for adult spinal deformity (ASD). OBJECTIVE: To elucidate the role of bone strength for developing PJF. SUMMARY OF BACKGROUND DATA: PJF, a devastating complication of corrective surgery for ASD, often recurs even after revision surgery. Most studies of risk factors for PJF are retrospective and have a selection bias in surgical strategy, making it difficult to identify modifiable PJF risk factors...
August 1, 2017: Spine
https://www.readbyqxmd.com/read/28767613/effect-of-greater-trochanteric-epiphysiodesis-after-femoral-varus-osteotomy-for-lateral-pillar-classification-b-and-b-c-border-legg-calv%C3%A3-perthes-disease-a-retrospective-observational-study
#10
Keun-Sang Kwon, Sung Il Wang, Ju-Hyung Lee, Young Jae Moon, Jung Ryul Kim
This is a retrospective observational study. Greater trochanteric epiphysiodesis (GTE) has been recommended to prevent Trendelenburg gait and limitation of the hip joint motion due to trochanteric overgrowth after femoral varus osteotomy (FVO) in Legg-Calvé-Perthes disease (LCPD). However, capital femoral physeal arrest frequently occurs in patients with severe disease (lateral pillar C), so GTE might not be as effective in these patients. The aim of this study was to compare trochanteric growth inhibition due to GTE after FVO between 2 age groups (<8 or >8 years) in patients with lateral pillar B and B/C border LCPD and evaluate the effectiveness of GTE compared with the normal, unaffected hip...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28760318/the-horizontal-inclination-angle-is-associated-with-the-risk-of-inferior-alveolar-nerve-injury-during-the-extraction-of-mandibular-third-molars
#11
S Ishii, S Abe, A Moro, N Yokomizo, Y Kobayashi
The extraction of mandibular third molars can lead to injury to the inferior alveolar nerve. Hence, it is important to assess the proximity of the root to the inferior alveolar canal before extraction. The classification system of Pell and Gregory and the Winter classification are commonly used to evaluate the positional relationship of the third molar based on radiographs. This retrospective study involving 105 mandibular third molars was performed to assess whether these systems reflect the proximity of the root to the canal (based on computed tomography images), and to identify risk factors for nerve injury...
July 29, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28757287/sagittal-lumbo-pelvic-alignment-in-patients-with-low-back-pain-and-the-effects-of-a-high-load-lifting-exercise-and-individualized-low-load-motor-control-exercises-a-randomized-controlled-trial
#12
Lars Berglund, Björn Aasa, Peter Michaelson, Ulrika Aasa
Background Context Assessment of posture and lumbo-pelvic alignment is often a main focus in the classification and treatment of patients with low back pain. However, little is known regarding the effects of motor control interventions on objective measures of lumbo-pelvic alignment. Purpose The primary aim of this study was to describe the variation of sagittal lumbo-pelvic alignment in patients with nociceptive mechanical low back pain. The secondary aim was to compare the effects of a high-load lifting exercise (HLL) and low-load motor control exercises (LMC) on change in lumbo-pelvic alignment with a special emphasis on patients with high and low degrees of lumbar lordosis (lu) and sacral angle (sa)...
July 28, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28755923/proximal-sacral-deformity-a-common-element-in-lytic-isthmic-spondylolisthesis-at-l5-and-in-degenerative-spondylolisthesis-at-l4-l5-segment-two-apparently-very-different-etiopathogenic-entities
#13
A Gallego-Goyanes, D Barahona-Lorenzo, M A Díez-Ulloa
A radiographic study was carried out to investigate the relationship between proximal sacral sagittal anatomy (either kyphosis or lordosis) and either isthmic or degenerative spondylolisthesis. In addition, we studied whether there is a relationship between proximal sacral kyphosis and the degree of such listhesis in the case of L5 isthmic spondylolisthesis. Lateral standing x-rays were used from 173 patients, ninety of whom had degenerative spondylolisthesis L4-L5, and eighty-three an isthmic spondylolisthesis of L5 (67 low-grade and 16 high-grade) and compared with a control group of 100 patients adjusted by age and gender, without any type of spondylolisthesis...
July 26, 2017: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/28744729/low-angled-microcatheter-approach-for-coil-embolization-of-the-anterior-choroidal-artery-aneurysm
#14
Jae Jon Sheen, Dae Chul Suh
PURPOSE: Thromboembolic complication is a serious concern following coil embolization for aneurysms involving the anterior choroidal artery (AChA). To minimize this complication and to improve packing density, we present a technical concept of coil embolization. METHODS: We attempted packing of the aneurysmal sac by lowering the microcatheter approach angle into an aneurysm to secure AChA origin as well as to improve coil packing density of the aneurysm. This technical concept involves approaching the aneurysm sac with an adjusted shaping of the microcatheter tip to achieve the effect which was not obtained when the microcatheter approach angle into the aneurysm sac was high (≥90°)...
July 25, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28735766/risk-factor-analysis-for-predicting-vertebral-body-re-collapse-after-posterior-instrumented-fusion-in-thoracolumbar-burst-fracture
#15
Hae-Dong Jang, Jae Chul Lee, Jae-Wan Soh, Sung-Woo Choi, Hyeung-Kyu Cho, Byung-Joon Shin
BACKGROUND CONTEXT: In the posterior instrumented fusion surgery for thoracolumbar (T-L) burst fracture, early postoperative re-collapse of well-reduced vertebral body fracture could induces critical complications such as correction loss, post-traumatic kyphosis, metal failure, often lead to revision surgery. Furthermore, re-collapse is quite difficult to predict because of the variety of risk factors and no widely accepted accurate prediction systems existed. Although load sharing classification (LSC) has been known to help to decide the need for additional anterior column support, this radiographic scoring system has several critical limitations...
July 20, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28735137/endonasal-operative-corridor-expansion-by-sphenoidal-pneumosinus-dilatans-in-tuberculum-sellae-meningiomas
#16
Amol Raheja, Michael Karsy, Ilyas Eli, Jian Guan, William T Couldwell
A retrospective cohort study of patients with tuberculum sellae meningioma (TSM)-associated sphenoidal pneumosinus dilatans (PSD) over a recent epoch was evaluated using a propensity-matched morphometric analysis. A total of 38 patients with TSM and sphenoidal PSD were identified and matched by age and sex to 32 patients without tumors (controls). Overall, no significant difference between test and control groups was noted in sphenoid sinus size or other parameters; however, significantly greater mean distance from the posterior margin of the planum sphenoidale to the diaphragma sella (0...
July 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28733722/non-specific-chronic-low-back-pain-differences-in-spinal-kinematics-in-subgroups-during-functional-tasks
#17
Rebecca Hemming, Liba Sheeran, Robert van Deursen, Valerie Sparkes
PURPOSE: A multidimensional classification approach suggests that motor control impairment subgroups exist in non-specific chronic low back pain (NSCLBP). Differences in sitting lumbar posture have been identified between two such subgroups [flexion pattern (FP) and active extension pattern (AEP)] and healthy individuals; however, functional spinal movement has not been explored. This study will evaluate whether NSCLBP subgroups exhibit regional spinal kinematic differences, compared to healthy individuals, during functional tasks...
July 21, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28727778/in-vitro-study-of-accuracy-of-subaxial-cervical-pedicle-screw-insertion-using-calipers-based-on-the-gravity-line
#18
Xiang Yao, Shiqing Liu
OBJECT: There is a high probability of iatrogenic perforation of the vertebral pedicle wall during the application of subaxial cervical pedicle screw (CPS). The goal of this study was to evaluate the accuracy of CPS insertion at C3-C7 in vitro using novel calipers based on the gravity line. METHODS: Nine cadaveric cervical spines underwent computed tomography scanning and preoperative design. A lateral fluoroscopic view was taken to measure the intra-operative sagittal angle by C-arm with hanging cross structured K-wires...
2017: PloS One
https://www.readbyqxmd.com/read/28724097/influence-of-long-term-application-of-feedlot-manure-amendments-on-water-repellency-of-a-clay-loam-soil
#19
Jim J Miller, Bruce W Beasley, Paul Hazendonk, Craig F Drury, David S Chanasyk
Long-term application of feedlot manure to cropland may increase the quantity of soil organic carbon (C) and change its quality, which may influence soil water repellency. The objective was to determine the influence of feedlot manure type (stockpiled vs. composted), bedding material (straw [ST] vs. woodchips [WD]), and application rate (13, 39, or 77 Mg ha) on repellency of a clay loam soil after 17 annual applications. The repellency was determined on all 14 treatments using the water repellency index ( index), the water drop penetration time (WDPT) method, and molarity of ethanol (MED) test...
May 2017: Journal of Environmental Quality
https://www.readbyqxmd.com/read/28713739/a-retrospective-analysis-of-dentofacial-deformities-and-orthognathic-surgeries
#20
Faezeh Eslamipour, Ali Borzabadi-Farahani, Bach T Le, Majid Shahmoradi
BACKGROUND: Information regarding the prevalence of surgical osteotomies used for the correction of dentofacial deformities in Iran is lacking. MATERIALS AND METHODS: This retrospective cross-sectional study assessed the distribution of orthognathic surgeries performed (2011-2015) at major University hospital in Iran. Records of 103 orthognathic surgery patients were assessed (58 female, 45 males, aged = 23.47 [6.44] years). RESULTS: Class III malocclusion (incisor classification, 45...
January 2017: Annals of Maxillofacial Surgery
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