keyword
https://read.qxmd.com/read/38586715/emergent-management-of-severe-hypothermia-acidemia-and-coagulopathy-in-operative-penetrating-ballistic-cranial-trauma
#1
Nicholas Dietz, Meghan Blank, William Asaka, Brent G Oxford, Dale Ding, Emily Sieg, Heidi M Koenig
Hypothermia in a trauma patient has been associated with increased morbidity and mortality and is more frequently seen in those sustaining traumatic brain injuries (TBIs). Acidosis is an important consequence of hypothermia that leads to derangements across the spectrum of the coagulation cascade. Here, we present a case of a 31-year-old male presented after suffering a right parietal penetrating ballistic injury with an associated subdural hematoma and 7 mm midline shift requiring decompressive craniectomy and external ventricular drain (EVD) placement in the setting of severe hypothermia (28°C) and acidosis (pH 7...
March 2024: Curēus
https://read.qxmd.com/read/38548927/natural-warming-differentiates-communities-and-increases-diversity-in-deep-sea-ridge-flank-hydrothermal-systems
#2
JOURNAL ARTICLE
Anne M Hartwell, Anna E Wheat, Jennifer A Dijkstra
Ridge Flank Hydrothermal Systems have discrete pockets of fluid discharge that mimic climate-induced ocean warming. Unlike traditional hydrothermal fluids, those discharged by Ridge Flank Hydrothermal Systems have a chemical composition indistinguishable from background water, enabling evaluation of the effect of warming temperature. Here we link temperature and terrain variables to community composition and biodiversity by combining remotely operated vehicle images of vent and non-vent zone communities with associated environmental variables...
March 28, 2024: Communications Biology
https://read.qxmd.com/read/38516761/beyond-skeletal-studies-a-computational-analysis-of-nasal-airway-function-in-climate-adaptation
#3
JOURNAL ARTICLE
Markus Bastir, Daniel Sanz-Prieto, Manuel A Burgos, Alejandro Pérez-Ramos, Yann Heuzé, Laura Maréchal, Andrej Evteev, Viviana Toro-Ibacache, Francisco Esteban-Ortega
OBJECTIVES: Ecogeographic variation in human nasal anatomy has historically been analyzed on skeletal morphology and interpreted in the context of climatic adaptations to respiratory air-conditioning. Only a few studies have analyzed nasal soft tissue morphology, actively involved in air-conditioning physiology. MATERIALS AND METHODS: We used in vivo computer tomographic scans of (N = 146) adult individuals from Cambodia, Chile, Russia, and Spain. We conducted (N = 438) airflow simulations during inspiration using computational fluid dynamics to analyze the air-conditioning capacities of the nasal soft tissue in the inflow, functional, and outflow tract, under three different environmental conditions: cold-dry; hot-dry; and hot-humid...
March 22, 2024: American journal of biological anthropology
https://read.qxmd.com/read/38500914/characteristics-of-polycystic-ovary-syndrome-a-case-report-investigating-the-role-of-kapha-and-pitta-doshas
#4
Ritesh Jadhav, Akash More, Shirish Vaidya, Namrata Choudhary, Shilpa Dutta, Krushnali S Kadu, Gauri Gajabe
Polycystic ovary syndrome (PCOS) presents complex challenges in diagnosis and treatment due to its multifactorial nature. This case study focuses on a 31-year-old woman exhibiting symptoms of weight gain, irregular menstruation cycles, and hirsutism, leading to a diagnosis of PCOS. Conventional diagnostic criteria and ultrasound confirmation of multiple ovarian cysts supported the diagnosis. By integrating Ayurvedic principles alongside Western medical techniques, this study sought to address imbalances in the Kapha and Pitta doshas, fundamental energies according to Ayurveda, believed to contribute to PCOS symptoms...
February 2024: Curēus
https://read.qxmd.com/read/38487095/microfluidic-delivery-of-high-viscosity-liquids-using-piezoelectric-micropumps-for-subcutaneous-drug-infusion-applications
#5
JOURNAL ARTICLE
Nivedha Surendran, Claudia Patricia Durasiewicz, Thalia Hoffmann, Axel Wille, Agnes Beate Bussmann, Martin Richter
Goal: Auto-injectors for self-administration of drugs are usually refrigerated. If not warmed up prior to the injection, ejection of the total drug volume is not guaranteed, as their spring and plunger mechanism cannot adjust for a change in viscosity of the drug. Here, we develop piezoelectric micro diaphragm pump that allows these modifications possible while investigating the effectiveness of this alternative dosing method. Methods: The dosing of highly viscous liquid of 25 mPa·s is made possible using application-specific micropump design...
2024: IEEE open journal of engineering in medicine and biology
https://read.qxmd.com/read/38473122/the-effect-of-saponite-clay-on-ruminal-fermentation-parameters-during-in-vitro-studies
#6
JOURNAL ARTICLE
Alina Pikhtirova, Ewa Pecka-Kiełb, Bożena Króliczewska, Andrzej Zachwieja, Jarosław Króliczewski, Robert Kupczyński
Reducing the emission of global warming gases currently remains one of the strategic tasks. Therefore, the objective of our work was to determine the effect of saponite clay on fermentation in the rumen of cows. The pH, total gas production, CH4 , and volatile fatty acid (VFA) production in ruminal fluid was determined in vitro. Saponite clay from the Tashkiv deposit (Ukraine) has a high content of silicon, iron, aluminum, and magnesium. The addition of 0.15 and 0.25 g of saponite clay to the incubated mixture did not change the pH but reduced the total production (19% and 31%, respectively) and CH4 (24% and 46%, respectively) in the ruminal fluid compared to the control group and had no significant effect on the total VFA levels, but propionic acid increased by 15% and 21% and butyric acid decreased by 39% and 32%, respectively...
February 27, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38468650/essentials-for-early-diagnosis-of-primary-intramedullary-spinal-cord-lymphoma-how-to-suspect-primary-intramedullary-spinal-cord-lymphoma-early-and-proceed-to-invasive-biopsy-a-case-report-and-literature-review
#7
Seiji Shigekawa, Akihiro Inoue, Yukihiro Miyazaki, Mashio Taniwaki, Kota Kanehisa, Sayaka Matsumoto, Yoko Okada, Riko Kitazawa, Takeharu Kunieda
BACKGROUND: Primary intramedullary spinal cord lymphoma (PISCL) is an extremely rare condition. Early diagnosis is very difficult due to the nonspecific clinical and imaging findings. A biopsy is essential for a definitive diagnosis, but courage is required to perform the surgery. Here, we present a case of PISCL and suggest useful indicators for accurate diagnosis of this pathological entity. CASE DESCRIPTION: A 70-year-old woman presented with subacute bilateral lower-limb paralysis, disturbance of warm and pain sensations, and vesicorectal disturbance...
2024: Surgical Neurology International
https://read.qxmd.com/read/38463874/mitochondrial-dna-levels-in-perfusate-and-bile-during-ex-vivo-normothermic-machine-correspond-with-donor-liver-quality
#8
JOURNAL ARTICLE
Lauren P Westhaver, Sarah Nersesian, Riley J Arseneau, Joshua Hefler, Breanna K V Hargreaves, Alexander Edgar, Yara Azizieh, Nerea Cuesta-Gomez, Dayne L Izquierdo, A M James Shapiro, Boris L Gala-Lopez, Jeanette E Boudreau
Ex vivo normothermic machine perfusion (NMP) preserves donor organs and permits real-time assessment of allograft health, but the most effective indicators of graft viability are uncertain. Mitochondrial DNA (mtDNA), released consequent to traumatic cell injury and death, including the ischemia-reperfusion injury inherent in transplantation, may meet the need for a biomarker in this context. We describe a real time PCR-based approach to assess cell-free mtDNA during NMP as a universal biomarker of allograft quality...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38433341/temperature-and-co-2-interactively-drive-shifts-in-the-compositional-and-functional-structure-of-peatland-protist-communities
#9
JOURNAL ARTICLE
Christopher L Kilner, Alyssa A Carrell, Daniel J Wieczynski, Samantha Votzke, Katrina DeWitt, Andrea Yammine, Jonathan Shaw, Dale A Pelletier, David J Weston, Jean P Gibert
Microbes affect the global carbon cycle that influences climate change and are in turn influenced by environmental change. Here, we use data from a long-term whole-ecosystem warming experiment at a boreal peatland to answer how temperature and CO2 jointly influence communities of abundant, diverse, yet poorly understood, non-fungi microbial Eukaryotes (protists). These microbes influence ecosystem function directly through photosynthesis and respiration, and indirectly, through predation on decomposers (bacteria and fungi)...
March 2024: Global Change Biology
https://read.qxmd.com/read/38373790/continuous-rise-in-oxygen-consumption-during-prolonged-military-loaded-march-in-the-heat-with-and-without-fluid-replacement-a-pilot-study
#10
JOURNAL ARTICLE
Courtney E Wheelock, J Stooks, J Schwob, D Hostler
INTRODUCTION: V̇O2 drift, the rise in oxygen consumption during continuous exercise, has not been adequately reported during prolonged military marches. The purpose of this study was to analyse V̇O2 and energy expenditure (EE) during a loaded march with and without rehydration efforts. Second, the study aimed to compare EE throughout the march with predicted values using a validated model. METHODS: Seven healthy men (23±2 years; V̇O2max : 50...
February 19, 2024: BMJ military health
https://read.qxmd.com/read/38333824/carbon-capture-utilization-and-storage-opportunities-to-mitigate-greenhouse-gases
#11
REVIEW
Muhammad Imran Rashid, Zahida Yaqoob, M A Mujtaba, M A Kalam, H Fayaz, Atika Qazi
Carbon capture, utilization and storage (CCUS) technologies are utmost need of the modern era. CCUS technologies adoption is compulsory to keep global warming below 1.5 °C. Mineral carbonation (MC) is considered one of the safest and most viable methods to sequester anthropogenic carbon dioxide (CO2 ). MC is an exothermic reaction and occur naturally in the subsurface because of fluid-rock interactions with serpentinite. In serpentine carbonation, CO2 reacts with magnesium to produce carbonates. This article covers CO2 mitigation technologies especially mineral carbonation, mineral carbonation by natural and industrial materials, mineral carbonation feedstock availability in Pakistan, detailed characterization of serpentine from Skardu serpentinite belt, geo sequestration, oceanic sequestration, CO2 to urea and CO2 to methanol and other chemicals...
February 15, 2024: Heliyon
https://read.qxmd.com/read/38325151/blastocoel-fluid-aspiration-improves-vitrification-outcomes-and-produces-similar-sexing-results-of-in-vitro-produced-cattle-embryos-compared-to-microblade-biopsy
#12
JOURNAL ARTICLE
Iris Martínez-Rodero, Albert Salas-Huetos, Judith Diaz-Muñoz, Erika Alina Ordóñez-León, Tania García-Martínez, Marc Yeste, Carlos Olegario Hidalgo, Teresa Mogas
The potential applications of in vitro-produced (IVP) cattle embryos are significantly enhanced when combined with genotype selection and cryopreservation techniques. While trophectoderm (TE) biopsies are frequently used for genotyping, cell-free DNA (cfDNA) found in blastocoele fluid (BF) arises as a less-invasive method. Moreover, the blastocoel collapse produced by BF aspiration could be beneficial for embryo cryotolerance. This study was conducted to test the BF as a source of cell free-DNA (cfDNA) and to compare the BF to the TE biopsy in terms of sexing efficiency/accuracy, embryo survival and gene expression after vitrification/warming...
February 1, 2024: Theriogenology
https://read.qxmd.com/read/38316563/separation-of-oral-cooling-and-warming-requires-trpm8
#13
JOURNAL ARTICLE
Jinrong Li, Kyle T Zumpano, Christian H Lemon
Cooling sensations arise inside the mouth during ingestive and homeostasis behaviors. Oral presence of cooling temperature engages the cold and menthol receptor TRPM8 (transient receptor potential melastatin 8) on trigeminal afferents. Yet, how TRPM8 influences brain and behavioral responses to oral temperature is undefined. Here we used in vivo neurophysiology to record action potentials stimulated by cooling and warming of oral tissues from trigeminal nucleus caudalis neurons in female and male wild-type and TRPM8 gene deficient mice...
February 5, 2024: Journal of Neuroscience
https://read.qxmd.com/read/38314682/mycobacterium-flavescens-infection-an-unusual-case-of-prosthetic-joint-infection
#14
Peter Holleb, Srijisnu De, Suresh Antony
INTRODUCTION: The onset of prosthetic joint infections (PJIs) is characterized by early on-set defined as within 90 days of the procedure, delayed onset defined as within 3 to 12 months, and late onset defined as over 12 months. In only a scant number of case reports, Mycobacterium flavescens-associated infections are typically found in sputum cultures and associated with various forms of penetrating joint traumas, particularly post-surgical interventions. Due to its rarity in presentation among cases of PJIs, we have presented a case of PJI caused by Mycobacterium fla-vescens...
January 17, 2024: Infectious Disorders Drug Targets
https://read.qxmd.com/read/38281313/morphological-and-biochemical-responses-of-a-neotropical-pest-insect-to-low-temperatures
#15
JOURNAL ARTICLE
Trinidad León-Quinto, Roque Madrigal, Esteban Cabello, Antonio Fimia, Arturo Serna
As traditionally cold areas become warmer due to climate change, temperature could no longer be a barrier to the establishment of non-native insects. This is particularly relevant for pest insects from warm and tropical areas, mainly those with some tolerance to moderately low temperatures, which could expand their range into these new locations. From this perspective, in this work we studied the morphological and biochemical responses of the Neotropical pest Paysandisia archon to low temperatures, as part of a possible strategy to colonize new areas...
January 24, 2024: Journal of Thermal Biology
https://read.qxmd.com/read/38267410/low-k-nano-dielectrics-facilitate-electric-field-induced-phase-transition-in-high-k-ferroelectric-polymers-for-sustainable-electrocaloric-refrigeration
#16
JOURNAL ARTICLE
Qiang Li, Luqi Wei, Ni Zhong, Xiaoming Shi, Donglin Han, Shanyu Zheng, Feihong Du, Junye Shi, Jiangping Chen, Houbing Huang, Chungang Duan, Xiaoshi Qian
Ferroelectric polymer-based electrocaloric effect may lead to sustainable heat pumps and refrigeration owing to the large electrocaloric-induced entropy changes, flexible, lightweight and zero-global warming potential. Herein, low-k nanodiamonds are served as extrinsic dielectric fillers to fabricate polymeric nanocomposites for electrocaloric refrigeration. As low-k nanofillers are naturally polar-inactive, hence they have been widely applied for consolidate electrical stability in dielectrics. Interestingly, we observe that the nanodiamonds markedly enhances the electrocaloric effect in relaxor ferroelectrics...
January 24, 2024: Nature Communications
https://read.qxmd.com/read/38267400/a-laparoscopically-compatible-rapid-adhesion-bioadhesive-for-asymmetric-adhesion-non-pressing-hemostasis-and-seamless-seal
#17
JOURNAL ARTICLE
Yueying Yang, Jiaxin Wang, Jiashen Yang, Xiaoyu Wu, Ye Tian, Hanchuan Tang, Na Li, Xurui Liu, Mengyuan Zhou, Jihong Liu, Qing Ling, Jianfeng Zang
Bioadhesive hydrogels offer unprecedented opportunities in hemostatic agents and tissue sealing; however, the application of existing bioadhesive hydrogels through narrow spaces to achieve strong adhesion in fluid-rich physiological environments is challenged either by undesired indiscriminate adhesion or weak wet tissue adhesion. Here, a laparoscopically compatible asymmetric adhesive hydrogel (aAH) composed of sprayable adhesive hydrogel powders and injectable anti-adhesive glue is proposed for hemostasis and to seal the bloody tissues in a non-pressing way, allowing for preventing postoperative adhesion...
January 24, 2024: Advanced Healthcare Materials
https://read.qxmd.com/read/38258830/partial-and-complete-fluid-replacement-maintains-exercise-performance-in-a-warm-environment-following-prolonged-cold-water-immersion
#18
JOURNAL ARTICLE
Courtney E Wheelock, Jocelyn Stooks, Jacqueline Schwob, Hayden W Hess, Riana R Pryor, David Hostler
Wheelock, CE, Stooks, J, Schwob, J, Hess, HW, Pryor, RR, and Hostler, D. Partial and complete fluid replacement maintains exercise performance in a warm environment following prolonged cold-water immersion. J Strength Cond Res 38(2): 290-296, 2024-Special warfare operators may be exposed to prolonged immersion before beginning a land-based mission. This immersion will result in substantial hypohydration because of diuresis. This study tested the hypothesis that both partial and full postimmersion rehydration would maintain performance during exercise in the heat...
February 1, 2024: Journal of Strength and Conditioning Research
https://read.qxmd.com/read/38164352/effect-of-10-minutes-of-prewarming-and-prewarmed-intravenous-fluid-administration-on-the-core-temperature-of-patients-undergoing-transurethral-surgery-under-general-anesthesia
#19
RANDOMIZED CONTROLLED TRIAL
Joonho Cho, Jin-Min Lee, Kye-Min Kim, Jun Heum Yon, Hye Sun Lee, In-Jung Jun
Background: Patients undergoing transurethral urologic procedures using bladder irrigation are at increased risk of perioperative hypothermia. Thirty minutes of prewarming prevents perioperative hypothermia. However, its routine application is impractical. We evaluated the effect of 10 minutes of prewarming combined with the intraoperative administration of warmed intravenous fluid on patients' core temperature. Methods: Fifty patients undergoing transurethral bladder or prostate resection under general anesthesia were included in this study and were randomly allocated to either the control group or the prewarming group...
2024: International Journal of Medical Sciences
https://read.qxmd.com/read/38159580/effect-of-prewarmed-crystalloid-fluids-and-an-in-line-fluid-warming-device-on-fluid-outflow-temperatures-at-ambient-temperatures-of-21-22%C3%A2-c-and-3-5%C3%A2-c
#20
JOURNAL ARTICLE
Lindsay C Monroe, Jarrod R Troy, Clark Kogan, Jamie J Kopper
Equine veterinarians frequently treat patients in non-climate-controlled (i.e., hospitalized) settings. In colder environments, intravenous (IV) fluid administration can contribute to patient hypothermia. The objective of this study was to evaluate three IV fluid warming mechanisms to determine their effect on fluid outflow temperatures at ambient temperatures of 21-22°C and 3.5°C. In this study, fluid outflow temperatures were measured using three warming mechanisms: (1) pre-warmed fluids at 42°C, (2) an in-line warming device placed 163 cm away from the Luer-lock fluid line adaptor (location 1) on the fluid line, and (3) an in-line warming device placed 88 cm away from the Luer-lock fluid line adaptor (location 2) on the fluid line...
December 28, 2023: Journal of Equine Veterinary Science
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