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https://www.readbyqxmd.com/read/28721503/salinity-drives-the-virioplankton-abundance-but-not-production-in-tropical-coastal-lagoons
#1
Pedro C Junger, André M Amado, Rodolfo Paranhos, Anderson S Cabral, Saulo M S Jacques, Vinicius F Farjalla
Viruses are the most abundant components of microbial food webs and play important ecological and biogeochemical roles in aquatic ecosystems. Virioplankton is regulated by several environmental factors, such as salinity, turbidity, and humic substances. However, most of the studies aimed to investigate virioplankton regulation were conducted in temperate systems combining a limited range of environmental variables. In this study, virus abundance and production were determined and their relation to bacterial and limnological variables was assessed in 20 neighboring shallow tropical coastal lagoons that present wide environmental gradients of turbidity (2...
July 18, 2017: Microbial Ecology
https://www.readbyqxmd.com/read/28717379/hepatoprotective-effect-of-citral-on-acetaminophen-induced-liver-toxicity-in-mice
#2
Nancy Sayuri Uchida, Saulo Euclides Silva-Filho, Gabriel Fernando Esteves Cardia, Edivaldo Cremer, Francielli Maria de Souza Silva-Comar, Expedito Leite Silva, Ciomar Aparecida Bersani-Amado, Roberto Kenji Nakamura Cuman
High doses of acetaminophen (APAP) lead to acute liver damage. In this study, we evaluated the effects of citral in a murine model of hepatotoxicity induced by APAP. The liver function markers alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and gamma-glutamyl transferase (γGT) were determined to evaluate the hepatoprotective effects of citral. The livers were used to determine myeloperoxidase (MPO) activity and nitric oxide (NO) production and in histological analysis...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28713535/strength-training-with-repetitions-to-failure-does-not-provide-additional-strength-and-muscle-hypertrophy-gains-in-young-women
#3
Saulo Martorelli, Eduardo Lusa Cadore, Mikel Izquierdo, Rodrigo Celes, André Martorelli, Vitor Alonso Cleto, José Gustavo Alvarenga, Martim Bottaro
This study investigated the effects of a 10-week resistance training to failure on neuromuscular adaptations in young women. Eighty-nine active young women were randomly assigned to one of three groups: 1) repetitions to failure (RF; three sets of repetitions to failure); 2) repetitions not to failure with equalized volume (RNFV; four sets of 7 repetitions); and 3) repetitions not to failure (RNF; three sets of 7 repetitions). All groups performed the elbow flexor exercise (bilateral biceps curl) and trained 2 days per week using 70% of 1RM...
June 24, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/28709370/sewers-as-potential-reservoirs-of-antibiotic-resistance
#4
Olga Auguet, Maite Pijuan, Carles M Borrego, Sara Rodriguez-Mozaz, Xavier Triadó-Margarit, Saulo Varela Della Giustina, Oriol Gutierrez
Wastewater transport along sewers favors the colonization of inner pipe surfaces by wastewater-derived microorganisms that grow forming biofilms. These biofilms are composed of rich and diverse microbial communities that are continuously exposed to antibiotic residues and antibiotic resistant bacteria (ARB) from urban wastewater. Sewer biofilms thus appear as an optimal habitat for the dispersal and accumulation of antibiotic resistance genes (ARGs). In this study, the concentration of antibiotics, integron (intI1) and antibiotic resistance genes (qnrS, sul1, sul2, blaTEM, blaKPC, ermB, tetM and tetW), and potential bacterial pathogens were analyzed in wastewater and biofilm samples collected at the inlet and outlet sections of a pressurized sewer pipe...
July 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28693992/characterization-of-a-recombinant-xylose-tolerant-%C3%AE-xylosidase-from-humicola-grisea-var-thermoidea-and-its-use-in-sugarcane-bagasse-hydrolysis
#5
Lorena Cardoso Cintra, Amanda Gregorim Fernandes, Izadora Cristina Moreira de Oliveira, Saulo J Linhares Siqueira, Ilítia Ganaê Oliveira Costa, Francieli Colussi, Rosália Santos Amorim Jesuíno, Cirano José Ulhoa, Fabrícia Paula de Faria
One full-length β-xylosidase gene (hxylA) was identified from the Humicola grisea var. thermoidea genome and the cDNA was successfully expressed by Pichia pastoris SMD1168. An optimization of enzyme production was carried out, and methanol was found to be the most important parameter. The purified enzyme was characterized and showed the optimal conditions for the highest activity at pH 7.0 and 50°C, being thermostable by maintaining 41% of its activity after 12h incubated at 50°C. HXYLA is a bifunctional enzyme; it showed both β-xylosidase and α-arabinfuranosidase activities...
July 7, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28690085/comparison-of-cone-beam-computed-tomography-and-digital-intraoral-radiography-performance-in-the-detection-of-artificially-induced-recurrent-caries-like-lesions
#6
Saulo Leonardo Sousa Melo, Manuella Dias Furtado Belem, Lucia Trazzi Prieto, Cinthia Pereira Machado Tabchoury, Francisco Haiter-Neto
OBJECTIVES: The aim of this study was to compare the performance of cone beam computed tomography (CBCT) and digital radiography in the detection of artificial recurrent caries-like lesions under amalgam and composite fillings. STUDY DESIGN: The study included class II cavities in 30 molars that had been filled with amalgam. Fifteen of those molars had the restoration-enamel interface artificially demineralized. Phantoms were prepared, and CBCT images were acquired with 2 units in 3 voxel sizes (K9000, 0...
May 11, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28675812/pre-emptive-effect-of-dexamethasone-and-diclofenac-sodium-associated-with-codeine-on-pain-swelling-and-trismus-after-third-molar-surgery-a-split-mouth-randomized-triple-blind-controlled-clinical-trial
#7
Thiago César Lima, Elizabete Bagordakis, Saulo Gabriel Moreira Falci, Cássio Roberto Rocha Dos Santos, Marcos Luciano Pimenta Pinheiro
PURPOSE: We aimed to compare the effect of dexamethasone, 8 mg, and diclofenac sodium, 50 mg, associated with codeine, 50 mg, on the control of pain, swelling, and trismus after extraction of impacted third molars. MATERIALS AND METHODS: Fifteen healthy patients with a mean age of 22.8 years (SD, 12.62 years) received a single oral dose of either drug 1 hour before each surgical procedure (left and right teeth). At 24, 48, and 72 hours after surgery, swelling was determined by use of linear measurements on the face and trismus was determined by maximal mouth opening...
June 14, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28641157/design-synthesis-and-structure-activity-relationship-studies-of-a-novel-focused-library-of-2-3-4-substituted-oxazolidines-with-antiproliferative-activity-against-cancer-cell-lines
#8
Saulo F Andrade, Bárbara G Oliveira, Larissa C Pereira, Jonas P Ramos, Angélica R Joaquim, Martin Steppe, Elaine M Souza-Fagundes, Ricardo J Alves
In the present work we describe the synthesis and antiproliferative evaluation of a focused library of 30 novel oxazolidines designed by modification of N-substituent, by ring variation, by alkyl variation or by extension of the structure. It was noted that carbamate and N,O-aminal groups were essential for activity. In general, replacement of the phenyl ring with pyridinyl was not tolerated. However, the introduction of a second phenyl ring with an appropriate spacer at the 3- or 4-position of the first phenyl ring generally enhanced the cytotoxic profile...
June 12, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28604146/clients-and-carers-perception-of-mental-illness-and-factors-that-influence-help-seeking-where-they-go-first-and-why
#9
Harris K Chilale, Ndumanene Devlin Silungwe, Saulos Gondwe, Charles Masulani-Mwale
OBJECTIVE: In Northern Malawi, the duration of untreated psychosis (DUP) is longer than that in high-income countries. The reasons for the delay in help-seeking are not known, although studies show multiple reasons. This research was conducted to establish health care help-seeking behaviours and identify barriers that exist between service users and health care providers. The study also intended to establish the beliefs that clients and family members have regarding the causes of mental illness which profoundly shape help-seeking, care giving process and outcomes...
June 1, 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/28602259/assessment-of-condyle-position-fossa-morphology-and-disk-displacement-in-symptomatic-patients
#10
Katharina Alves Rabelo, Saulo Leonardo Sousa Melo, Marianna Guanaes Gomes Torres, Larissa Rangel Peixoto, Paulo Sérgio Flores Campos, Iêda Margarida Crusoé Rocha Rebello, Daniela Pita de Melo
OBJECTIVE: The aim of the study was to determine whether there are any associations between the morphology of the glenoid fossa, articular spaces, and disk displacement by evaluating the magnetic resonance imaging (MRI) scans of symptomatic patients. Gender and age were also evaluated for any effect on the parameters. STUDY DESIGN: MRI scans of 199 temporomandibular joints were assessed for the morphology of the glenoid fossa and articular spaces in both sagittal and coronal views...
April 19, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28597384/toxicity-against-drosophila-melanogaster-and-antiedematogenic-and-antimicrobial-activities-of-alternanthera-brasiliana-l-kuntze-amaranthaceae
#11
Henrique Douglas Melo Coutinho, Cícera Datiane de Morais Oliveira-Tintino, Saulo Relison Tintino, Raimundo Luiz Silva Pereira, Thiago Sampaio de Freitas, Maria Arlene Pessoa da Silva, Jeferson Luis Franco, Francisco Assis Bezerra da Cunha, José Galberto Martins da Costa, Irwin Rose Alencar de Menezes, Aline Augusti Boligon, João Batista Teixeira da Rocha, Maria Ivaneide Rocha, Joycy Francely Sampaio Dos Santos
Bioactive phytocompounds are studied by several bioactivities demonstrated, as their cytotoxic effects. The aim of this work was to evaluate the phytochemical profile, the toxic effect using the Drosophila melanogaster animal model and the anti-inflammatory and antimicrobial effect of the Alternanthera brasiliana (EEAB) ethanol extract. The phytochemical profile was performed using HPLC. The cytotoxic effect was evaluated in vivo using D. melanogaster. The anti-inflammatory effect was determined by neurogenic and antiedematogenic assays, and the antimicrobial activity was assayed using a microdilution method to determine the minimum inhibitory concentration (MIC) of the EEAB alone and in association with antibiotics...
June 8, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28597210/multiple-desmoplastic-cellular-neurothekeomas-in-child-report-of-the-first-oral-case-and-review-of-the-literature
#12
Tatiana Fernandes Araújo Almeida, Flaviana Dornela Verli, Cássio Roberto Rocha Dos Santos, Saulo Gabriel Moreira Falci, Luciana Yamamoto Almeida, Lana Kei Yamamoto Almeida, Ana Terezinha Marques Mesquita, Jorge Esquiche León
Cellular neurothekeomas (CNs) are distinctive benign tumors of uncertain histogenesis, with predilection for the skin of the head and neck region. We describe the first case of multiple desmoplastic CNs (DCNs) affecting the oral cavity in a 9-year-old girl. Histopathologic evaluation showed a proliferation of spindle and epithelioid cells, forming nests and bundles, supported by exuberant fibrous stroma, as well as scattered multinucleated floret-like giant cells. The tumor cells were immunopositive for vimentin, CD63, CD56, whereas AE1/AE3, S100, CD34, α-SMA, GFAP, EMA, CD57 and NSE were negative...
June 8, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28595855/dissociated-time-course-between-peak-torque-and-total-work-recovery-following-bench-press-training-in-resistance-trained-men
#13
Diogo V Ferreira, Paulo Gentil, João B Ferreira-Junior, Saulo R S Soares, Lee E Brown, Martim Bottaro
OBJECTIVE: To evaluate the time course of peak torque and total work recovery after a resistance training session involving the bench press exercise. DESIGN: Repeated measures with a within subject design. METHODS: Twenty-six resistance-trained men (age: 23.7±3.7years; height: 176.0±5.7cm; mass: 79.65±7.61kg) performed one session involving eight sets of the bench press exercise performed to momentary muscle failure with 2-min rest between sets...
June 7, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28587978/a-new-arginine-based-dental-adhesive-system-formulation-mechanical-and-anti-caries-properties
#14
Saulo Geraldeli, Eveline F Soares, Andres J Alvarez, Tanaz Farivar, Robert C Shields, Mario A C Sinhoreti, Marcelle M Nascimento
Secondary caries at the margins of composite restorations has been attributed to adhesive failure and consequent accumulation of cariogenic biofilms. OBJECTIVES: To develop and evaluate an etch-and-rinse adhesive system containing arginine for sustainable release and recharge without affecting its mechanical properties. Arginine metabolism by oral bacteria generates ammonia, which neutralizes glycolytic acids and creates a neutral environmental pH that is less favorable to the growth of caries pathogens, thus reducing the caries risk at the tooth-composite interface...
June 3, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28571537/synthesis-and-biological-evaluation-of-new-tyrosol-salicylate-derivatives-as-potential-anti-inflammatory-agents
#15
Rafael P Aguiar, Fahad S Aldawsari, Luiz A M Wiirzler, Saulo E Silva-Filho, Francielli M S Silva-Comar, Ciomar A Bersani-Amado, Carlos A Velázquez-Martínez, Roberto K N Cuman
Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly used medications in inflammatory illnesses. However, the gastrointestinal bleeding and toxicity associated with NSAIDs long term use prompted the quest towards investigations for new anti-inflammatory agents. Natural and natural-derived molecules proved its anti-inflammatory efficacy in vitro as well as in vivo. Given this background, the scope of this research involves structural changes of the natural polyphenol (tyrosol) generating two new salicylate derivatives and testing their biological properties , focusing in anti-inflammatory effects assessed in vitro and in vivo assays...
June 1, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28569446/the-effect-of-lithium-disilicate-opacity-on-polymerization-of-a-dual-cured-resin-cement
#16
Dylton da Costa Neto, Jefferson Pereira, Saulo Pamato, Accácio do Valle
The aim of this study was to evaluate the influence of different levels of opacity of the lithium disilicate framework upon polymerization of dual-cured resin cement. Four ceramic discs were used, one for each opacity framework covered by their respective ceramic veneering, and a cement group without a ceramic cover. The degree of conversion for each resin cement was estimated using the Knoop microhardness test. The group with the highest opacity showed the lowest hardness score at baseline. The study concluded that the opacity level of lithium disilicate framework could influence the degree of polymerization of a dual-cured resin cement...
March 2017: European Journal of Prosthodontics and Restorative Dentistry
https://www.readbyqxmd.com/read/28554453/impact-of-cone-beam-computed-tomography-scan-mode-on-the-diagnostic-yield-of-chemically-simulated-external-root-resorption
#17
Saulo L Sousa Melo, Karla de Faria Vasconcelos, Nathan Holton, Veeratrishul Allareddy, Veerasathpurush Allareddy, Cinthia Pereira Machado Tabchoury, Francisco Haiter-Neto, Axel Ruprecht
INTRODUCTION: The aim of this in-vitro study was to evaluate the influence of cone-beam computed tomography scans on the diagnosis of chemically simulated external root resorption. METHODS: One hundred extracted anterior teeth were selected. Subsurface demineralization was induced on a limited area of the apical third of the root of 49 teeth. Each tooth was placed in an empty socket of a partially edentulous dry mandible. Cone-beam computed tomography images were obtained according to 3 protocols: (1) half scan, 0...
June 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/28538294/effects-of-different-combinations-of-strength-power-and-plyometric-training-on-the-physical-performance-of-elite-young-soccer-players
#18
Ronaldo Kobal, Irineu Loturco, Renato Barroso, Saulo Gil, Rogério Cuniyochi, Carlos Ugrinowitsch, Hamilton Roschel, Valmor Tricoli
The combination of strength (ST) and plyometric training (PT) has been shown to be effective for improving sport-specific performance. However, there is no consensus about the most effective way to combine these methods in the same training session to produce greater improvements in neuromuscular performance of soccer players. Thus, the purpose of this study was to compare the effects of different combinations of ST and PT sequences on strength, jump, speed, and agility capacities of elite young soccer players...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28510282/cytologic-features-of-a-feline-inductive-odontogenic-tumor
#19
Ronaldo V Leite-Filho, Nelson J Tagliari, Fabrizio Grandi, Cláudio J M Laisse, Daniel G Gerardi, Saulo P Pavarini
The feline inductive odontogenic tumor (FIOT) is a rare entity among oral tumors in cats, the cytologic features of which are not well characterized but may prove useful. A fine-needle aspiration biopsy was performed on the right mandible between the permanent canine (404) and permanent fourth premolar (408) of an 8-month-old female mongrel cat. Cytologic smears showed epithelial cells and occasional spindle cells with extracellular homogenous acidophilic material in a hematic background. The initial diagnosis of benign tumor was confirmed by histopathologic examination of the biopsy specimen...
May 16, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28489169/mortality-of-urgency-versus-elective-videolaparoscopic-cholecystectomy-for-acute-cholecystitis
#20
Saulo José Oliveira Felício, Ediriomar Peixoto Matos, Antonio Maurício Cerqueira, Kurt Wolfgang Schindler Freire de Farias, Ramon de Assis Silva, Mateus de Oliveira Torres
Background: Surgical approach is still controversial in patients with acute cholecystitis: to treat clinically the inflammatory process and operate electively later or to operate immediately on an emergency basis? Aim: To test the hypothesis that urgent laparoscopic cholecystectomy in acute cholecystitis has a higher mortality than elective laparoscopic cholecystectomy. Methods: From the data available in Datasus, mortality was compared between patients undergoing elective laparoscopic cholecystectomy for cholelithiasis and in urgency...
January 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
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