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https://www.readbyqxmd.com/read/28421126/femoral-neck-strain-during-maximal-contraction-of-isolated-hip-spanning-muscle-groups
#1
Saulo Martelli
The aim of the study was to investigate femoral neck strain during maximal isometric contraction of the hip-spanning muscles. The musculoskeletal and the femur finite-element models from an elderly white woman were taken from earlier studies. The hip-spanning muscles were grouped by function in six hip-spanning muscle groups. The peak hip and knee moments in the model were matched to corresponding published measurements of the hip and knee moments during maximal isometric exercises about the hip and the knee in elderly participants...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28391889/changes-in-low-density-lipoprotein-size-phenotypes-associate-with-changes-in-apolipoprotein-c-iii-glycoforms-after-dietary-interventions
#2
Saulo Mendoza, Olgica Trenchevska, Sarah M King, Randall W Nelson, Dobrin Nedelkov, Ronald M Krauss, Hussein N Yassine
BACKGROUND: The presence of small dense low-density lipoprotein (LDL) is associated with obesity, type II diabetes, and an increased risk for cardiovascular disease. Apolipoprotein C-III (apoC-III) is involved in the formation of small dense LDL, but the exact mechanisms are still not well defined. ApoC-III is a glycosylated apolipoprotein, with 3 major glycoforms: apoC-III0, apoC-III1, and apoC-III2 that contain 0, 1, or 2 molecules of sialic acid, respectively. In our previous work, we reported an association among apoC-III0 and apoC-III1, but not apoC-III2 with fasting plasma triglyceride levels in obesity and type II diabetes...
January 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28380089/relationship-between-articular-eminence-inclination-and-alterations-of-the-mandibular-condyle-a-cbct-study
#3
Saione Cruz Sa, Saulo Leonardo Sousa Melo, Daniela Pita de Melo, Deborah Queiroz Freitas, Paulo Sérgio Flores Campos
This study aimed at verifying the correlation among angulation of the articular eminence (AE), shape of the condyle and its degenerative bone diseases (DBDs), according to age and sex, through Cone Beam Computed Tomography (CBCT). Five hundred and twenty-eight temporomandibular joints (TMJ) were evaluated. The condyles were classified as: flat, convex, angled and rounded, and the AE angulation was measured. The DBDs evaluated were osteophytes, flattening, erosion, subcortical cysts and spinal sclerosis. There was no difference in the mean angulations in relation to age group (p>0...
March 30, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28379341/biocontainers-an-open-source-and-community-driven-framework-for-software-standardization
#4
Felipe da Veiga Leprevost, Björn A Grüning, Saulo Alves Aflitos, Hannes L Röst, Julian Uszkoreit, Harald Barsnes, Marc Vaudel, Pablo Moreno, Laurent Gatto, Jonas Weber, Mingze Bai, Rafael C Jimenez, Timo Sachsenberg, Julianus Pfeuffer, Roberto Vera Alvarez, Johannes Griss, Alexey I Nesvizhskii, Yasset Perez-Riverol
Motivation: BioContainers (biocontainers.pro) is an open-source and community-driven framework which provides platform independent executable environments for bioinformatics software. BioContainers allows labs of all sizes to easily install bioinformatics software, maintain multiple versions of the same software and combine tools into powerful analysis pipelines. BioContainers is based on popular open-source projects Docker and rkt frameworks, that allow software to be installed and executed under an isolated and controlled environment...
March 30, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28359875/seasonal-variation-of-brazilian-red-propolis-antibacterial-activity-synergistic-effect-and-phytochemical-screening
#5
Marcos da Silveira Regueira Neto, Saulo Relison Tintino, Ana Raquel Pereira da Silva, Maria do Socorro Costa, Aline Augusti Boligon, Edinardo F F Matias, Valdir de Queiroz Balbino, Irwin R A Menezes, Henrique Douglas Melo Coutinho
The aim of this study was to investigate the effect of the dry and rainy season on the antibacterial activity and chemical composition of the Brazilian red propolis. The samples were collected in rainy (RP-PER) and dry (RP-PED) seasons and analyzed by HPLC-DAD. The extracts were tested alone and in association with antibiotics against Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. The HPLC analysis identified luteolin and quercetin as the main compounds. Seasonal variation was observed according to concentrations of the compounds...
March 27, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28359199/protective-effect-of-cymbopogon-citratus-essential-oil-in-experimental-model-of-acetaminophen-induced-liver-injury
#6
Nancy Sayuri Uchida, Saulo Euclides Silva-Filho, Rafael Pazinatto Aguiar, Luiz Alexandre Marques Wiirzler, Gabriel Fernando Esteves Cardia, Heitor Augusto Otaviano Cavalcante, Francielli Maria de Souza Silva-Comar, Tânia Cristina Alexandrino Becker, Expedito Leite Silva, Ciomar Aparecida Bersani-Amado, Roberto Kenji Nakamura Cuman
To investigate the hepatoprotective effect of Cymbopogon citratus or lemongrass essential oil (LGO), it was used in an animal model of acute liver injury induced by acetaminophen (APAP). Swiss mice were pretreated with LGO (125, 250 and 500[Formula: see text]mg/kg) and SLM (standard drug, 200[Formula: see text]mg/kg) for a duration of seven days, followed by the induction of hepatotoxicity of APAP (single dose, 250[Formula: see text]mg/kg). The liver function markers alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and gamma-glutamyl transferase were determined to evaluate the hepatoprotective effects of the LGO...
March 30, 2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/28325584/development-of-a-surrogate-model-based-on-patient-weight-bone-mass-and-geometry-to-predict-femoral-neck-strains-and-fracture-loads
#7
Mark Taylor, Egon Perilli, Saulo Martelli
Osteoporosis and related bone fractures are an increasing global burden in our ageing society. Areal bone mineral density assessed through dual energy X-ray absorptiometry (DEXA), the clinically accepted and most used method, is not sufficient to assess fracture risk individually. Finite element (FE) modelling has shown improvements in prediction of fracture risk, better than aBMD from DEXA, but is not practical for widespread clinical use. The aim of this study was to develop an adaptive neural network (ANN)-based surrogate model to predict femoral neck strains and fracture loads obtained from a previously developed population-based FE model...
April 11, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28320909/theoretical-and-computational-studies-of-non-equilibrium-and-non-statistical-dynamics-in-the-gas-phase-in-the-condensed-phase-and-at-interfaces
#8
Riccardo Spezia, Emilio Martínez-Nuñez, Saulo Vazquez, William L Hase
In this Introduction, we show the basic problems of non-statistical and non-equilibrium phenomena related to the papers collected in this themed issue. Over the past few years, significant advances in both computing power and development of theories have allowed the study of larger systems, increasing the time length of simulations and improving the quality of potential energy surfaces. In particular, the possibility of using quantum chemistry to calculate energies and forces 'on the fly' has paved the way to directly study chemical reactions...
April 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28318536/chromobacterium-violaceum-infection-in-a-horse
#9
Márcia Elisa Hammerschmitt, Veronica Machado Rolim, Gustavo Geraldo Medina Snel, Franciele Maboni Siqueira, David Driemeier, Saulo Petinatti Pavarini
Chromobacterium violaceum is an opportunistic pathogen of mammals that produces characteristic violet pigment in bacterial culture. We report pneumonia and septicaemia caused by C. violaceum in a horse. Necropsy examination was performed on a 3-year-old Quarter Horse stallion with a history of recurrent episodes of pneumonia, fever, dyspnoea and sanguineous nasal discharge. The lungs were not collapsed, but they contained dark red foci mixed with white areas, and multiple nodules of firm consistency. Within the liver and kidney there were randomly distributed, multifocal, white pinpoint lesions (0...
March 16, 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28301790/human-papillomavirus-vaccination-and-genital-warts-in-young-indigenous-australians-national-sentinel-surveillance-data
#10
Hammad Ali, Hamish McManus, Catherine C O'Connor, Denton Callander, Marlene Kong, Simon Graham, Dina Saulo, Christopher K Fairley, David G Regan, Andrew Grulich, Nicola Low, Rebecca J Guy, Basil Donovan
OBJECTIVES: To examine the impact of the national human papillomavirus (HPV) vaccination program (available to girls and women [12-26 years] since 2007 and to boys [12-15 years] since 2013) on the number of diagnoses of genital warts in Australian Aboriginal and Torres Strait Islander (Indigenous) people. DESIGN, SETTING, PARTICIPANTS: Analysis of routinely collected data from patients attending 39 sexual health clinics (SHCs) in the Genital Warts Surveillance Network for the first time...
March 20, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28286381/rotary-instrument-or-piezoelectric-for-the-removal-of-third-molars-a-meta-analysis
#11
REVIEW
Rafael Alvim Magesty, Endi Lanza Galvão, Carolina de Castro Martins, Cássio Roberto Rocha Dos Santos, Saulo Gabriel Moreira Falci
AIM: The aim of this systematic review and meta-analysis was to compare, in the lower third molar surgery, the osteotomy techniques with rotary instruments and piezoelectric motors. METHODS: An electronic search was conducted using the following databases: Pubmed, Web of Science, and the Cochrane Oral Health Group Trials Register. Inclusion criteria were: studies in humans, randomized or nonrandomized, comparing the extraction of third molars that required osteotomy and/or odontosection with rotary instrument and osteotomy and/or odontosection with piezoelectric motor assistance...
March 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28253179/prevalence-of-pathologic-findings-in-the-floor-of-the-maxillary-sinuses-on-cone-beam-computed-tomography-images
#12
Aline Fernanda Almeida Da Silva, Gontran Rocha Torres Fróes, Wilton Mitsunari Takeshita, Juliana Batista Melo Da Fonte, Maria Fátima Batista De Melo, Saulo Leonardo Sousa Melo
This study evaluated pathologic findings in the floor of the maxillary sinuses on cone beam computed tomography (CBCT) images. CBCT scans of 500 subjects, mainly taken for dental implant planning, were evaluated. The pathologic findings in the 1000 maxillary sinuses (left and right) were categorized into 4 classes: mucosal thickening, mucous retention pseudocyst, partial opacification, and total opacification. Pathologic alterations were equally found in both sinuses (48.2% of right maxillary sinuses and 48...
March 2017: General Dentistry
https://www.readbyqxmd.com/read/28239353/transient-receptor-potential-ankyrin-1-channel-expression-on-peripheral-blood-leukocytes-from-rheumatoid-arthritic-patients-and-correlation-with-pain-and-disability
#13
Ione Pereira, Saulo J F Mendes, Domingos M S Pereira, Thayanne F Muniz, Valderlane L P Colares, Cinara R A V Monteiro, Mahiba M R de S Martins, Marcos A G Grisotto, Valério Monteiro-Neto, Sílvio G Monteiro, João B Calixto, Susan D Brain, Elizabeth S Fernandes
Patients with rheumatoid arthritis (RA) suffer from pain and joint disability. The transient receptor potential ankyrin 1 (TRPA1) channel expressed on sensory neurones and non-neuronal cells mediates pain transduction and inflammation and it has been implicated in RA. However, there is little information on the contribution of TRPA1 for human disease. Here, we investigated the expression of TRPA1 on peripheral blood leukocytes and the circulating levels of its endogenous activators 4-hydroxynonenal (4-HNE) and hydrogen peroxide (H2O2) in RA patients treated or not with the anti-rheumatic leflunomide (LFN) or the anti-TNFα adalimumab (ADA)...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28238773/inhibition-of-the-tetk-efflux-pump-by-the-essential-oil-of-chenopodium-ambrosioides-l-and-%C3%AE-terpinene-against-staphylococcus-aureus-is-58
#14
Paulo W Limaverde, Fábia F Campina, Francisco A B da Cunha, Francidalva D Crispim, Fernando G Figueredo, Luciene F Lima, Cícera Datiane de M Oliveira-Tintino, Yedda M L S de Matos, Maria Flaviana B Morais-Braga, Irwin R A Menezes, Valdir Q Balbino, Henrique D M Coutinho, José P Siqueira-Júnior, Jackson R G S Almeida, Saulo R Tintino
The use of natural products is crucial to suppress the development of these micro-organisms and to reduce the concentration necessary to inhibit these microrganisms, reducing the toxicity risks also. In this study, the essential oil from Chenopodium ambrosioides Leaves and its main constituent α-Terpinene were used in the antibacterial and potentiating activity of antibiotics and ethidium bromide assays, against the bacterial strains Staphylococcus aureus IS-58, carriers of efflux pumps. The Minimum Inhibitory Concentration (MIC) was determined using a microdilution method...
February 23, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28230389/from-classicism-and-idealism-to-scientific-naturalism-titchener-s-oxford-years-and-their-impact-upon-his-early-intellectual-development
#15
Saulo de Freitas Araujo, Cintia Fernandes Marcellos
Edward Titchener (1867-1927) is one of the most prominent figures in the history of American psychology from the early 20th century. Accordingly, his psychological system-structuralism-has received due attention in the secondary literature. However, a closer look at traditional interpretations of the development of Titchener's ideas reveals a series of missing elements, such as his early studies before going to Leipzig. The central goal of this article is to present the main elements of Titchener's intellectual education in Oxford, thereby showing the influence of the British tradition of the 19th century upon his early intellectual development...
February 23, 2017: History of Psychology
https://www.readbyqxmd.com/read/28219631/condyle-excursion-angle-articular-eminence-inclination-and-temporomandibular-joint-morphologic-relations-with-disc-displacement
#16
Katharina Alves Rabelo, Saulo Leonardo Sousa Melo, Marianna Guanaes Gomes Torres, Paulo Sérgio F Campos, Patrícia Meira Bento, Daniela Pita de Melo
PURPOSE: The aim of this study was to evaluate the relations of the condyle excursion angle (CEA) and the morphology and morphometry of the articular eminence to disc displacement (DD) using magnetic resonance imaging (MRI) of symptomatic patients. MATERIALS AND METHODS: MRIs of 199 temporomandibular joints (TMJs) were evaluated. Qualitative and quantitative morphologic analyses were performed with tools available in PACS 11.0 (Carestream Health, Inc, Rochester, NY)...
January 29, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28216018/prospective-randomised-controlled-study-evaluating-early-modification-of-oral-microbiota-following-admission-to-the-intensive-care-unit-and-oral-hygiene-with-chlorhexidine
#17
Felipe Francisco Tuon, Oleg Gavrilko, Saulo de Almeida, Eigi Ricardo Sumi, Thiago Alberto, Jaime Luis Rocha, Edvaldo Antonio Rosa
OBJECTIVES: Chlorhexidine (CHX) is the most commonly used oral hygiene product for the prevention of ventilator-associated pneumonia (VAP) in patients undergoing mechanical ventilation (MV). The change in dental plaque (DP) microbiota following CHX use in patients under MV has not been described previously. The aim of this study was to evaluate the incidence of pathogenic bacteria associated with VAP and the coverage of DP within the oral cavity in patients administered CHX. METHODS: This was a prospective, randomised, controlled, double-blind study in patients (n=16) under MV who were mouth-rinsed with either CHX or placebo...
February 18, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28215783/synthesis-and-biological-evaluation-of-potential-inhibitors-of-the-cysteine-proteases-cruzain-and-rhodesain-designed-by-molecular-simplification
#18
Saulo Fehelberg Pinto Braga, Luan Carvalho Martins, Elany Barbosa da Silva, Policarpo Ademar Sales Júnior, Silvane Maria Fonseca Murta, Alvaro José Romanha, Wai Tuck Soh, Hans Brandstetter, Rafaela Salgado Ferreira, Renata Barbosa de Oliveira
Analogues of 8-chloro-N-(3-morpholinopropyl)-5H-pyrimido[5,4-b]indol-4-amine 1, a known cruzain inhibitor, were synthesized using a molecular simplification strategy. Five series of analogues were obtained: indole, pyrimidine, quinoline, aniline and pyrrole derivatives. The activity of the compounds was evaluated against the enzymes cruzain and rhodesain as well as against Trypanosoma cruzi amastigote and trypomastigote forms. The 4-aminoquinoline derivatives showed promising activity against both enzymes, with IC50 values ranging from 15 to 125µM...
February 9, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/28214274/intra-abdominal-fungal-pseudomycetoma-in-two-cats
#19
Matheus V Bianchi, Cláudio J M Laisse, Thainã P Vargas, Flademir Wouters, Fabiana M Boabaid, Saulo P Pavarini, Laerte Ferreiro, David Driemeier
BACKGROUND: Pseudomycetomas are deep cutaneous to subcutaneous lesions caused by Microsporum canis mainly described in Persian cats, with few reports of intra-abdominal location. This report describes the clinical signs and lesions of intra-abdominal pseudomycetomas caused by M. canis in two Persian cats. CASE REPORT: Two Persian cats with a history of previous laparotomy (ovariohysterectomy and nephrostomy) and fecal impaction were examined. Cat #1 was euthanized and subjected to necropsy, histopathology and mycological evaluation...
February 14, 2017: Revista Iberoamericana de Micología
https://www.readbyqxmd.com/read/28171606/comparing-co-evolution-methods-and-their-application-to-template-free-protein-structure-prediction
#20
Saulo Henrique Pires de Oliveira, Jiye Shi, Charlotte M Deane
No abstract text is available yet for this article.
February 1, 2017: Bioinformatics
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