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José Nunes de Alencar Neto, Saulo Rodrigo Ramalho de Moraes, Eduardo Back Sternick, Hein J J Wellens
Atypical bypass tracts or variants of ventricular pre-excitation are rare anatomic structures often with rate-dependent slowing in conduction, called decremental conduction. During sinus rhythm, electrocardiographic recognition of those structures may be difficult because unlike in the Wolff-Parkinson-White syndrome where usually overt ventricular pre-excitation is present, the electrocardiogram (ECG) often shows a subtle pre-excitation pattern because of less contribution to ventricular activation over the slow and decrementally conducting bypass...
May 16, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
David Ferro-Costas, Emilio Martínez-Núñez, Jesus Rodriguez-Otero, Enrique M Cabaleiro-Lago, Carlos M Estevez, Berta Fernandez, Antonio Fernandez-Ramos, Saulo A Vazquez
The potential energy surface involved in the thermal decomposition of 1-propanol radicals was investigated in detail using automated codes (tsscds2018 and Q2DTor). From the predicted elementary reactions, a relevant reaction network was constructed to study the decomposition at temperatures in the range 1000  2000 K. Specifically, this relevant network comprises 18 conformational reaction channels (CRCs), which in general exhibit a large wealth of conformers of reactants and transition states. Rate constants for all the CRCs were calculated using two approaches within the formulation of variational transition state theory (VTST), as incorporated in the TheRa program...
May 15, 2018: Journal of Physical Chemistry. A
Valterlúcio Dos Santos Sales, Álefe Brito Monteiro, Gyllyandeson de Araújo Delmondes, Emmily Petícia do Nascimento, Francisco Rodolpho Sobreira Dantas Nóbrega de Figuêiredo, Cristina Kelly de Souza Rodrigues, Josefa Fernanda Evangelista de Lacerda, Cícera Norma Fernandes, Maysa de Oliveira Barbosa, Adamo Xenofonte Brasil, Saulo Relison Tintino, Maria Celeste Vega Gomez, Cathia Coronel, Henrique Douglas Melo Coutinho, José Galberto Martins da Costa, Cícero Francisco Bezerra Felipe, Irwin Rose Alencar de Menezes, Marta Regina Kerntopf
With the increase of neglected diseases such as leishmaniasis and Chagas disease, there was a need for the search for new therapeutic alternatives that reduce the harm caused by medicine available for treatment. Thus, this study was performed to investigate the antiparasitic activity of the essential oil from the fruits of Piper tuberculatum Jacq, against lines of Leishmania braziliensis (MHOM/CO/88/UA301), Leishmania infantum (MHOM/ES/92/BCN83) and Trypanosoma cruzi (LC-B5 clone). Before running protocols, an analysis of the chemical composition of essential oil was conducted, which presented monoterpenes and sesquiterpenes...
2018: Iranian Journal of Pharmaceutical Research: IJPR
Cícera Datiane de Morais Oliveira-Tintino, Saulo Relison Tintino, Paulo W Limaverde, Fernando G Figueredo, Fábia F Campina, Francisco A B da Cunha, Roger H S da Costa, Pedro Silvino Pereira, Luciene F Lima, Yedda M L S de Matos, Henrique Douglas Melo Coutinho, José P Siqueira-Júnior, Valdir Q Balbino, Teresinha Gonçalves da Silva
This study was carried out to test the essential oil from C. ambrosioides leaves and its main constituent, α-Terpinene, in an antibacterial activity assay. As well, it was evaluated ability reduce resistance to norfloxacin and ethidium bromide was compared the Staphylococcus aureus 1199B whith 1199 wild type strain. The MIC of the C. ambrosioides essential oil and α-Terpinene were determined by microdilution method. The MIC of the essential oil and α-Terpinene presented a value ≥ 1024 μg/mL. However, when associated with antibacterials, the essential oil from C...
October 1, 2018: Food Chemistry
Gabriel Fernando Esteves Cardia, Saulo Euclides Silva-Filho, Expedito Leite Silva, Nancy Sayuri Uchida, Heitor Augusto Otaviano Cavalcante, Larissa Laila Cassarotti, Valter Eduardo Cocco Salvadego, Ricardo Alexandre Spironello, Ciomar Aparecida Bersani-Amado, Roberto Kenji Nakamura Cuman
Lavandula angustifolia is a plant of Lamiaceae family, with many therapeutic properties and biological activities, such as anticonvulsant, anxiolytic, antioxidant, anti-inflammatory, and antimicrobial activities. The aim of this study was to evaluate the effect of Lavandula angustifolia Mill. essential oil (LEO) on acute inflammatory response. LEO was analyzed using gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance spectroscopy (NMR) methods and showed predominance of 1,8-cineole (39...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Caíque Jordan Nunes Ribeiro, Andra Carla Santos de Araújo, Saulo Barreto Brito, Daniele Vieira Dantas, Mariangela da Silva Nunes, José Antonio Barreto Alves, Maria do Carmo de Oliveira Ribeiro
OBJECTIVE: To evaluate the validity and reliability of the Brazilian version of the Behavioral Pain Scale (BPS-Br) in victims of traumatic brain injury. METHODS: Observational prospective study with paired and repeated measures conducted at two intensive care units (clinical and surgical) of a large general hospital. The convenience sample consisted of adult victims of moderate or severe penetrating or blunt craniocerebral trauma who were sedated and mechanically ventilated...
March 2018: Revista Brasileira de Terapia Intensiva
Cláudio J Laisse, Carine K Souza, Paula R Pereira, Cíntia De Lorenzo, Matheus V Bianchi, Lourenço P Mapaco, Saulo P Pavarini, Cláudio W Canal, David Driemeier
Porcine circovirus-associated diseases (PCVADs), caused by porcine circovirus 2 (PCV-2), have a significant economic impact on the swine industry worldwide. In Africa, there is little information, to date, regarding the occurrence of PCV-2, and it has not been reported in Mozambique's swine population. We randomly collected mesenteric lymph nodes ( n = 111) from slaughtered pigs from 9 districts in southern Mozambique. PCV-2 DNA was detected in 54% (62 of 111) of the samples and 78% (23 of 31) of the farms...
May 2018: Journal of Veterinary Diagnostic Investigation
Thassiany Sarmento Oliveira de Almeida, Sayonara Maria Lia Fook, Saulo Rios Mariz, Edwirde Luiz Silva Camêlo, Lidiane Cristina Félix Gomes
In order to study data about suicide attempts and do the mapping of occurrence areas, it was developed an ecologic and exploring study, making use of techniques of geoprocessing, based on confirmed cases of suicide attempts. Cases of self-poisoning were included in the urban area of Campina Grande county, in the period of 2010-2013. A total of 446 suicide attempts were geo-referred, pointing up an incidence of 120 cases out of each 100,000 inhabitants. The sample was mostly feminine (66.4%), and 62.3% being up to 30 years old...
April 2018: Ciência & Saúde Coletiva
Saulo S Amorim, Roy A Norton, Anibal R Oliveira
Neopilizetes is a genus of the oribatid mite family Galumnidae that was first characterized by having well-developed setae, a dorsosejugal suture, and raised striae on the prodorsum and notogaster. It was proposed to accommodate Pilizetes neotropicus Balogh Mahunka 1978 from Brazil-the only supposed Pilizetes species known outside the Ethiopian Region-and it has remained monotypic. We found adults of N. neotropicus and four related species in soil-litter interface samples of a single cacao plantation in Ilhéus, Bahia, Brazil...
April 18, 2018: Zootaxa
Juliana Monteiro Balage, José Manuel Amigo, Daniel Silva Antonelo, Madeline Rezende Mazon, Saulo da Luz E Silva
Industry requires non-destructive real-time methods for quality control of meat in order to improve production efficiency and meet consumer expectations. Near Infrared Hyperspectral Images were used for tenderness evaluation of Nellore beef and the construction of tenderness distribution maps. To investigate whether the selection of the region of interest (ROI) in the image at the exact location where the shear force core was collected improves tenderness prediction and classification models, 50 samples from Longissimus muscle were imaged (1000-2500 nm) and shear force were measured (Warner-Bratzler)...
April 12, 2018: Meat Science
Marcos da Silveira Regueira-Neto, Saulo Relison Tintino, Miriam Rolón, Cathia Coronal, Maria C Vega, Valdir de Queiroz Balbino, Henrique Douglas de Melo Coutinho
The treatment for leishmaniasis and Chagas disease can be hard and painful, such that many patients give up on the treatment. In order to find an alternative path for the treatment of these diseases, researchers are using natural products to fight these parasites. The aim of this study was to evaluate the antiprotozoan and cytotoxic activities of red propolis samples collected from different Brazilian states and seasons whilst searching for possible activity differences. We also compared the red propolis results with the ones obtained for the plant resin extract collected from Dalbergia ecastophyllum trees...
April 14, 2018: Food and Chemical Toxicology
Luiz Filipe Gonçalves Oliveira, Franklin Souza-Silva, Luzia Monteiro de Castro Côrtes, Lea Cysne-Finkelstein, Mirian Cláudia de Souza Pereira, Francisco Odêncio de Oliveira Junior, Rosa Teixeira Pinho, Suzana Corte Real, Saulo Cabral Bourguignon, Vitor Francisco Ferreira, Carlos Roberto Alves
Epoxymethoxylawsone is a naphthoquinone derivative promising as drug candidate for the treatment of leishmaniases. In the present work the effectiveness of epoxymethoxylawsone, and meglumine antimoniate on Leishmania ( Leishmania ) amazonensis parasites and on mice paw lesions of infected BALB/c mice was assessed. In an intracellular amastigotes assay, the half-maximal inhibitory concentration (IC50 ) value for epoxymethoxylawsone was slightly higher (1.7-fold) than that found for meglumine antimoniate. The efficacy of both drugs became more evident after 48 h of exposure when either the oxirane compound and reference drug reached 18-fold and 7...
April 10, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Ricardo Andrade Furtado, Pollyanna Francielli de Oliveira, Juliana Marques Senedese, Saulo Duarte Ozelin, Larissa Daniela Ribeiro de Souza, Luís Fernando Leandro, Wendel Luiz de Oliveira, Jonas Joaquim Mangabeira da Silva, Larissa Costa Oliveira, Hervé Rogez, Sérgio Ricardo Ambrósio, Rodrigo Cassio Sola Veneziani, Jairo Kenupp Bastos, Denise Crispim Tavares
The uses of Copaifera species in folk medicine are related to a wide variety of pharmacological properties. This paper reports the cytotoxic and genotoxic analyses of oleoresins and leaves extracts of Copaifera species: C. duckei, C. multijuga, C. paupera, C. pubiflora, C. reticulata and C. trapezifolia. In vitro assays were performed using Chinese hamster lung fibroblasts (V79 cells). The clonogenic efficiency and cytokinesis-block micronucleus assays were employed for the cytotoxicity and genotoxicity assessment, respectively...
April 3, 2018: Journal of Ethnopharmacology
José Cristiano Ramos Glória, Ighor Andrade Fernandes, Esmeralda Maria da Silveira, Glaciele Maria de Souza, Ricardo Lopes Rocha, Endi Lanza Galvão, Saulo Gabriel Moreira Falci
Introduction  Mandibular fractures represent a high percentage of all facial fractures, and the bite force is a fundamental parameter to measure the actual mandibular function and, subsequently, the masticatory efficiency and quality of life. Objectives  The purpose of the present systematic review was to verify if there is any difference in the bite forces of patients with mandibular fractures fixed by locking or non-locking plates, testing the null hypothesis of no difference in this parameter. Data Synthesis  A systematic review of the literature was conducted using four databases (PubMed, Virtual Health Library, Web of Science and Science Direct) without restrictions as to publication date or language...
April 2018: International Archives of Otorhinolaryngology
José Cristiano Ramos Glória, Carolina Castro Martins, Anna Catharina Vieira Armond, Endi Lanza Galvão, Cássio Roberto Rocha Dos Santos, Saulo Gabriel Moreira Falci
Purpose: The aim of this meta-analysis was to determine which characteristics of mandibular third molars (MTMs) are more often associated with an increase in the prevalence/incidence of caries on the distal surface of mandibular second molars (MSMs). Methods: Three electronic databases were analyzed: PubMed; OVID and the Virtual Health Library. Observational studies were included, and the risk of bias was assessed using The Newcastle-Ottawa Scale. The Comprehensive Meta-Analysis software program was used for meta-analysis...
June 2018: Journal of Maxillofacial and Oral Surgery
Saulo Fernandes de Mattos Dourado, Denise Frediani Barbeiro, Marcia Kiyomi Koike, Hermes Vieira Barbeiro, Fabiano Pinheiro da Silva, Marcel Cerqueira César Machado
BACKGROUND: Intestinal ischemia reperfusion is a common clinical condition that causes functional impairment. Once tight junctions are damaged, barrier function is compromised, and the intestines become a source for entry of bacterial and inflammatory mediators into the circulation, leading to systemic inflammatory response syndrome, multiple organ failure, and death. It is possible that diazoxide could protect the intestines against ischemia reperfusion. The aim of this study is to determine whether diazoxide can provide protection in a rat model of intestinal ischemia reperfusion...
May 2018: Journal of Surgical Research
Raphael Schezaro-Ramos, Saulo L Da Silva, Beatriz B Pereira, Ananda T Santa Fé Miguel, Bruno Mendes, Noroska G S Mogollón, Stephen Hyslop, Victor C Carregari, José R Almeida
The neuromuscular effect of rattlesnake venoms is not a major clinical manifestation shared between rattlesnakes native to the Americas, which showed two different venom phenotypes. Taking into account this dichotomy, nerve muscle preparations from mouse and chicks were used to investigate the ability of Crotalus atrox venom to induce in vitro neurotoxicity and myotoxicity. Unlike crotalic venoms of South America, low doses of C. atrox venom did not result in significant effects on mouse neuromuscular preparations...
March 28, 2018: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
J Parera, B H Aristizabal, M G Martrat, M A Adrados, J Sauló, M Ábalos, E Abad
Reductions in concentrations of persistent organic pollutants were observed for polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in a comparison of two consecutive decades ending in December 31, 2015 (n = 413) and compiled from a 48-station long-term air-monitoring network in Catalonia, Spain. Reductions were observed in geometric mean concentration of total PCDD/Fs, decreasing at a rate of 11% yr-1 . Results reflect the relative success of improved pollution control measures at industry and traffic locations...
March 27, 2018: Science of the Total Environment
Cristiano Queiroz Melo Reis, Patricia Nicolucci, Saulo S Fortes, Leonardo P Silva
The purpose of this study is to evaluate the performance of dose calculation algorithms used in radiotherapy treatment planning systems (TPSs) in comparison with Monte Carlo (MC) simulations in nonelectronic equilibrium conditions. MC simulations with PENELOPE package were performed for comparison of doses calculated by pencil beam convolution (PBC), analytical anisotropy algorithm (AAA), and Acuros XB TPS algorithms. Relative depth dose curves were calculated in heterogeneous water phantoms with layers of bone (1...
March 26, 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
Luiz Carlos Caires-Júnior, Ernesto Goulart, Uirá Souto Melo, Bruno Henrique Silva Araujo, Lucas Alvizi, Alessandra Soares-Schanoski, Danyllo Felipe de Oliveira, Gerson Shigeru Kobayashi, Karina Griesi-Oliveira, Camila Manso Musso, Murilo Sena Amaral, Lucas Ferreira daSilva, Renato Mancini Astray, Sandra Fernanda Suárez-Patiño, Daniella Cristina Ventini, Sérgio Gomes da Silva, Guilherme Lopes Yamamoto, Suzana Ezquina, Michel Satya Naslavsky, Kayque Alves Telles-Silva, Karina Weinmann, Vanessa van der Linden, Helio van der Linden, João Ricardo Mendes de Oliveira, Nivia Maria Rodrigues Arrais, Adriana Melo, Thalita Figueiredo, Silvana Santos, Joanna Goes Castro Meira, Saulo Duarte Passos, Roque Pacheco de Almeida, Ana Jovina Barreto Bispo, Esper Abrão Cavalheiro, Jorge Kalil, Edécio Cunha-Neto, Helder Nakaya, Robert Andreata-Santos, Luis Carlos de Souza Ferreira, Sergio Verjovski-Almeida, Paulo Lee Ho, Maria Rita Passos-Bueno, Mayana Zatz
The original PDF version of this Article contained errors in the spelling of Luiz Carlos Caires-Júnior, Uirá Souto Melo, Bruno Henrique Silva Araujo, Alessandra Soares-Schanoski, Murilo Sena Amaral, Kayque Alves Telles-Silva, Vanessa van der Linden, Helio van der Linden, João Ricardo Mendes de Oliveira, Nivia Maria Rodrigues Arrais, Joanna Goes Castro Meira, Ana Jovina Barreto Bispo, Esper Abrão Cavalheiro, and Robert Andreata-Santos, which were incorrectly given as Luiz Carlos de Caires Jr., UiráSouto Melo, Bruno Silva Henrique Araujo, Alessandra Soares Schanoski, MuriloSena Amaral, Kayque Telles Alves Silva, Vanessa Van der Linden, Helio Van der Linden, João Mendes Ricardo de Oliveira, Nivia Rodrigues Maria Arrais, Joanna Castro Goes Meira, Ana JovinaBarreto Bispo, EsperAbrão Cavalheiro, and Robert Andreata Santos...
March 13, 2018: Nature Communications
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