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rheumatic mitral valve disease

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https://www.readbyqxmd.com/read/27908608/a-hospital-based-survey-of-patients-with-severe-valvular-heart-disease-in-china
#1
Po Hu, Xian-Bao Liu, Jie Liang, Qi-Feng Zhu, Chao-Xia Pu, Meng-Yao Tang, Jian-An Wang
OBJECTIVES: Due to increasing aging, the epidemiology of VHD may have changed in China. This study aimed to provide contemporary information on the prevalence, distribution patterns, and etiology of severe VHD in China. METHODS: This was a retrospective survey at Second Affiliated Hospital of Zhejiang University, which included all consecutive patients between 2010 and 2015. RESULTS: In all, 139,496 patients were enrolled. Among severe valve diseases, MR was the most frequent (n=946, 0...
November 25, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27878698/mitral-valve-enhancement-in-a-patient-with-active-rheumatic-fever-an-uncommon-phenomenon-on-the-mri-examination-with-possible-clinical-significance
#2
Karthik Gadabanahalli, Venkatraman Bhat, Satya Narayana
Intense enhancement of the mitral valve is documented in a MRI examination performed on a patient with rheumatic multi-valvular disease. Patient had the elevated inflammatory markers indicating active inflammatory process. Such hitherto undocumented phenomenon may have important clinical significance in disease evaluation, thus provide a feasible option to document and follow up, active valvular involvement in patients with active rheumatic fever.
November 23, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27876696/stroke-prevention-strategies-in-patients-with-atrial-fibrillation-and-heart-valve-abnormalities-perceptions-of-valvular-atrial-fibrillation-results-of-the-european-heart-rhythm-association-survey
#3
Tatjana S Potpara, Gregory Y H Lip, Torben B Larsen, Antonio Madrid, Dan Dobreanu, Ewa Jędrzejczyk-Patej, Nikolaos Dagres
The purpose of this European Heart Rhythm Association (EHRA) Survey was to assess the perceptions of 'valvular' atrial fibrillation (AF) and management of AF patients with various heart valve abnormalities in daily clinical practice in European electrophysiology (EP) centres. Questionnaire survey was sent via the Internet to the EHRA-EP Research Network Centres. Of the 52 responding centres, 42 (80.8%) were university hospitals. Choosing the most comprehensive definition of valvular AF, a total of 49 centres (94...
October 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27876001/severe-mitral-regurgitation-due-to-mitral-leaflet-aneurysm-diagnosed-by-three-dimensional-transesophageal-echocardiography-a-case-report
#4
Takao Konishi, Naohiro Funayama, Tadashi Yamamoto, Daisuke Hotta, Kenjiro Kikuchi, Katsumi Ohori, Hiroshi Nishihara, Shinya Tanaka
BACKGROUND: A small mitral valve aneurysm (MVA) presenting as severe mitral regurgitation (MR) is uncommon. CASE PRESENTATION: A 47-year-old man with a history of hypertension complained of exertional chest discomfort. A transthoracic echocardiogram (TTE) revealed the presence of MR and prolapse of the posterior leaflet. A 6-mm in diameter MVA, not clearly visualized by TTE, was detected on the posterior leaflet on a three-dimensional (3D) transesophageal echocardiography (TEE)...
November 22, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27861189/oral-anticoagulation-for-stroke-prevention-amongst-atrial-fibrillation-patients-with-valvular-heart-disease-an-update
#5
Andrew C T Ha, Atul Verma, Subodh Verma
PURPOSE OF REVIEW: The majority of evidence on the safety and efficacy of oral anticoagulation for stroke prevention amongst patients with atrial fibrillation is derived from those without significant valvular heart disease. This article will review current knowledge, areas of uncertainty and controversy, and ongoing research on oral anticoagulation for stroke prevention amongst patients with valvular heart disease. RECENT FINDINGS: The rates of stroke, systemic embolism, and major bleeding were similar for patients with and without significant native valvular disease when treated with direct oral anticoagulants (DOACs) or vitamin K antagonists...
November 18, 2016: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/27849305/treatment-of-chronic-atrial-fibrillation-during-surgery-for-rheumatic-mitral-valve-disease
#6
Flavio Donizete Gonçalves, Valdir Gonçalves Leite, Vanusa Gonçalves Leite, Marcelo Alves Maia, Otoni Moreira Gomes, Melchior Luiz Lima, Evandro César Vidal Osterne, Elias Kallás
Introduction: The result of surgical ablation of atrial fibrillation remains controversial, although prospective and randomized studies have shown significant differences in the return to sinus rhythm in patients treated with ablation versus control group. Surgery of the Labyrinth, proposed by Cox and colleagues, is complex and increases the morbidity rate. Therefore, studies are needed to confirm the impact on clinical outcomes and quality of life of these patients. Objective: To analyze the results obtained in the treatment of atrial fibrillation by surgical approach, by Gomes procedure, for mitral valve surgery in patients with rheumatic heart disease associated with chronic atrial fibrillation...
July 2016: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27849303/the-mid-term-results-of-patients-who-underwent-radiofrequency-atrial-fibrillation-ablation-together-with-mitral-valve-surgery
#7
Abdurrahim Çolak, Ugur Kaya, Munacettin Ceviz, Necip Becit, Hikmet Kocak
Objetive: Saline-irrigated radiofrequency ablation, which has been widely used for surgical treatment of atrial fibrillation in recent years, is 80-90% successful in achieving sinus rhythm. In our study, our surgical experience and mid-term results in patients who underwent mitral valve surgery and left atrial radiofrequency ablation were analyzed. Methods: Forty patients (15 males, 25 females; mean age 52.05±9.9 years; range 32-74) underwent surgery for atrial fibrillation associated with mitral valvular disease...
July 2016: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27801390/a-review-of-acute-rheumatic-fever-and-rheumatic-heart-disease-research-in-malaysia
#8
L C Hung, R Nadia
A total of 39 titles related to rheumatic fever or rheumatic heart disease in Malaysia were found with online literature search dating back to their inceptions and through 2014. Additional publications from conference journals were included. Nine papers were selected based on clinical relevance and future research implications. There were no population-based studies on the incidence or prevalence of ARF or RHD. In the 1980s, the incidence of admission due to ARF ranged from 2 to 21.1 per 100 000 paediatric admission per year...
June 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/27773402/spectrum-of-congenital-mitral-valve-abnormalities-associated-with-solitary-undifferentiated-papillary-muscle-in-adults
#9
Jagdish C Mohan, Madhu Shukla, Vishwas Mohan, Arvind Sethi
BACKGROUND: Congenital anomaly wherein the mitral valve leaflets are directly attached to the papillary muscle(s) (PM) with or without short under-developed chords is rarely reported in adults. Patients with two PMs with an intervening fibrous bridge have also been included under this head in previous studies. METHODS: Echocardiography enables accurate evaluation of the morphology and function of valve leaflets, chordae tendineae, and PM. This report describes a series of six patients aged 56-84 years who had abnormal mitral valve with a large solitary and anomalously inserted PM seen over a period of 3 years...
September 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27753898/os-01-07-clinical-importance-of-collagen-metabolism-markers-in-rheumatic-heart-valve-disease-in-indian-subpopulation
#10
Tanima Banerjee, Somaditya Mukherjee, Sudip Ghosh, Monodeep Biswas, Santanu Datta, Sanjib Pattari, Shelly Chatterjee, Arun Bandyopadhyay
OBJECTIVE: Rheumatic Heart Disease (RHD), a chronic acquired heart disorder results from Acute Rheumatic Fever. RHD is mostly prevalent in developing nations which is mainly diagnosed by transthoracic echocardiography. Till date, there is no biochemical marker for disease management. In the present study we aim to investigate whether mitral valve remodeling contributes to altered levels of circulating biomarkers of collagen metabolism in rheumatic heart disease. DESIGN AND METHOD: The study involved RHD subjects with before and after valve replacement surgery which includes age and sex matched controls...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27751265/right-atrial-myxoma-clinically-mimicking-recurrence-of-rheumatic-valve-disease-long-time-after-mitral-valve-repair
#11
Gauranga Majumdar, Surendra Agarwal, Shantanu Pande, Satyendra Tewari
Right atrial myxomas are rare. Its occurrence in a previously operated patient of rheumatic mitral stenosis posed clinical diagnostic challenge. We herein report a case of right atrial myxoma who had undergone mitral valve repair 20 years ago and now presented in congestive heart failure. The tumor was arising from the ostium of the coronary sinus and prolapsed into the right ventricle causing significant right ventricular inflow and outflow obstruction. Urgent repeat cardiac surgery was successfully performed to remove the tumor along with mitral valve replacement...
September 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27748474/giant-left-atrium-in-undersized-mitral-ring-annuloplasty
#12
Nicole Bertin, Aniello Pappalardo, Alessandro Minati, Gabriella Forti, Serena Favretto, Franco Pertoldi, Eleonora Ficarra, Francesco Pelizzo, Olga Vriz
Enlargement of left atrium occurs in patients with longstanding mitral valve disease due to chronic pressure and volume overload and occasionally left atrium reaches a massive enlargement, condition known as giant left atrium. It is most commonly associated with rheumatic mitral valve disease, both stenosis and regurgitation. This unique case deals with a 70-year-old woman who developed a giant left atrium due to a severe mitral regurgitation from complete prolapse of both mitral leaflets, as a consequence of previous undersized mitral ring annuloplasty...
October 14, 2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/27723665/real-life-multicenter-survey-evaluating-stroke-prevention-strategies-in-non-valvular-atrial-fibrillation-ramses-study
#13
Özcan Başaran, Osman Beton, Volkan Doğan, Mehmet Tekinalp, Ahmet Çağrı Aykan, Ezgi Kalaycıoğlu, İsmail Bolat, Onur Taşar, Özgen Şafak, Macit Kalçık, Mehmet Yaman, İbrahim Altun, Mustafa Özcan Soylu, Cevat Kırma, Murat Biteker
OBJECTIVE: Data regarding stroke prevention strategies in non-valvular atrial fibrillation (NVAF) are limited to vitamin K antagonists (VKAs). This study aimed to evaluate real-life stroke prevention strategies for NVAF patients in the era of non-VKA oral anticoagulants (NOACs). METHODS: We established a cross-sectional, multicenter, nationwide registry of NVAF patients. All consecutive atrial fibrillation (AF) patients and without mechanical heart valves or rheumatic mitral stenosis (but including those with any degree of mitral regurgitation) were enrolled in the ReAl-life Multicenter Survey Evaluating Stroke Prevention Strategies (RAMSES Study; ClinicalTrials...
October 2016: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/27703088/rheumatic-mitral-valve-disease-is-associated-with-worse-outcomes-in-stroke-a-thailand-national-database-study
#14
Adrian D Wood, Gurdeep S Mannu, Allan B Clark, Somsak Tiamkao, Kannikar Kongbunkiat, Joao H Bettencourt-Silva, Kittisak Sawanyawisuth, Narongrit Kasemsap, Raphae S Barlas, Mamas Mamas, Phyo Kyaw Myint
BACKGROUND AND PURPOSE: Rheumatic valvular heart disease is associated with the increased risk of cerebrovascular events, although there are limited data on the prognosis of patients with rheumatic mitral valve disease (RMVD) after stroke. METHODS: We examined the association between RMVD and both serious and common cardiovascular and noncardiovascular (respiratory and infective) complications in a cohort of hospitalized stroke patients based in Thailand. Factors associated with in-hospital mortality were also explored...
November 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27667121/differences-in-atrial-fibrillation%C3%A2-associated-proteins-between-the-left-and-right-atrial-appendages-from-patients-with-rheumatic-mitral-valve-disease-a-comparative-proteomic-analysis
#15
Hai Liu, Guangxian Chen, Hongsheng Zheng, Han Qin, Mengya Liang, Kangni Feng, Zhongkai Wu
The majority of proteomic studies have focused on identifying atrial fibrillation (AF)-associated proteins in the right atrium (RA), thus potential differences in AF‑associated proteins between the RA and left atrium (LA) remain unknown. The aim of the present study was to perform proteomic analysis to compare the potential differences in AF‑associated proteins between the right atrial appendage (RAA) and left atrial appendage (LAA) in patients with rheumatic mitral valve disease (RMVD). RAA and LAA tissues were obtained from 18 patients with RMVD (10 with AF) during mitral valve replacement surgery...
November 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27665342/case-images-left-atrial-appendage-ostial-stenosis-in-a-patient-with-rheumatic-mitral-valve-disease
#16
Muhittin Demirel, Cüneyt Toprak, Emrah Acar, Servet İzci, Lütfi Öcal
No abstract text is available yet for this article.
September 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/27643244/os-01-07-clinical-importance-of-collagen-metabolism-markers-in-rheumatic-heart-valve-disease-in-indian-subpopulation
#17
Tanima Banerjee, Somaditya Mukherjee, Sudip Ghosh, Monodeep Biswas, Santanu Datta, Sanjib Pattari, Shelly Chatterjee, Arun Bandyopadhyay
OBJECTIVE: Rheumatic Heart Disease (RHD), a chronic acquired heart disorder results from Acute Rheumatic Fever. RHD is mostly prevalent in developing nations which is mainly diagnosed by transthoracic echocardiography. Till date, there is no biochemical marker for disease management. In the present study we aim to investigate whether mitral valve remodeling contributes to altered levels of circulating biomarkers of collagen metabolism in rheumatic heart disease. DESIGN AND METHOD: The study involved RHD subjects with before and after valve replacement surgery which includes age and sex matched controls...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27574927/oral-anticoagulation-in-the-elderly-new-oral-anticoagulants-innovative-solution-for-an-old-problem
#18
Mario Barbosa, Luiz Menezes Falcão
Direct oral anticoagulants emerge as the most innovative and promising drug toward preventing and treating cardiovascular disease, raising great interest among the scientific community. Numerous studies and meta-analysis generated much data clarifying clinicians' doubts; however, uncertainties remain regarding their use in particular groups such as patients with prosthetic valves, in valvular atrial fibrillation (defined as atrial fibrillation related to mitral rheumatic heart disease or prosthetic heart valves), among the elderly, in paraneoplastic thromboembolism, in pulmonary embolism with hemodynamic compromise, and scarcity of specific antidotes...
August 29, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/27567391/characteristics-and-outcomes-of-indian-children-enrolled-in-a-rheumatic-heart-disease-registry
#19
Anurag Mehta, Anita Saxena, Rajnish Juneja, Sivasubramanian Ramakrishnan, Saurabh Gupta, Shyam Sundar Kothari
BACKGROUND: Rheumatic heart disease (RHD) causes significant morbidity among children of low and middle-income countries. We aimed to assess characteristics and outcomes of Indian children enrolled in a tertiary care hospital RHD registry. METHODS: Pediatric patients (≤18years) were prospectively enrolled over three years. We evaluated their clinical and echocardiographic characteristics, valvular interventions, adherence to penicillin prophylaxis, and mortality...
November 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27549547/a-rare-case-of-mitral-valve-prolapse-in-endomyocardial-fibrosis
#20
Joseph Xavier, Maruti Yamanappa Haranal, Shashidhar Ranga Reddy, Sharadaprasad Suryaprakash
Mitral valve prolapse in endomyocardial fibrosis (EMF) is an unusual entity. Literature search reveals only 1 report of mitral valve prolapse assosiated with EMF. A 32-year-old woman, of African origin, who presented with features of right heart failure, was diagnosed to have mitral valve prolapse of rheumatic origin with severe mitral regurgitation and severe pulmonary hypertension (PAH). Intraoperative findings lead to the diagnosis of EMF. We report this rare case of mitral valve prolapse in EMF, in a geographical area where rheumatic heart disease is endemic, to showcase how a rare manifestation of EMF can be misdiagnosed as that of rheumatic heart disease...
September 2016: Annals of Thoracic Surgery
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