Hui-Hsuan Lin, Chia-Lin Tsai, Chiao-Yun Tseng, Pei-Rong Yu, Pei-Yu Chiu, Cheng-Chin Hsu, Jing-Hsien Chen
Hypertension is a global health problem and leads to cardiovascular disease and renal injury. Solanum muricatum Aiton leaf extract, rich in flavonoids, is known for its antioxidant capacity. However, the effects of Solanum muricatum Aiton leaf extract on hypertension combined with inflammatory complications were unknown. This study aimed to investigate the impact of Solanum muricatum Aiton leaf extract on hypertension in vivo and in vitro. In vivo, Solanum muricatum Aiton leaf extract led to decrease high blood pressure, improve heart, aorta, and kidney pathology, and enhance the antioxidative activity in spontaneously hypertensive rats (SHR)...
January 25, 2024: Plant Foods for Human Nutrition