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https://www.readbyqxmd.com/read/28523742/bandgap-engineering-of-lead-free-double-perovskite-cs2agbibr6-through-trivalent-metal-alloying
#1
Kezhao Du, Weiwei Meng, Xiaoming Wang, Yanfa Yan, David B Mitzi
The double perovskite family, A2MIMIIIX6, represents a promising route to overcome the lead toxicity issue confronting current photovoltaic (PV) standout, CH3NH3PbI3. Given the generally large indirect bandgap within most known double perovskites, bandgap engineering provides an important approach for targeting outstanding PV performance within this family. Using Cs2AgBiBr6 as host, we demonstrate bandgap engineering through alloying of InIII/SbIII. Cs2Ag(Bi1-xMx)Br6 (M = In, Sb) accommodates up to 75% InIII with increased bandgap, and up to 37...
May 18, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28498826/divergent-influences-of-cardiovascular-disease-risk-factor-domains-on-cognition-grey-and-white-matter-morphology
#2
Mitzi M Gonzales, Olusola Ajilore, Rebecca C Charlton, Jamie Cohen, Shaolin Yang, Erica Sieg, Dulal K Bhaumik, Anand Kumar, Melissa Lamar
OBJECTIVE: Hypertension, diabetes, dyslipidemia, and obesity are associated with preclinical alterations in cognition and brain structure; however, this often comes from studies of comprehensive risk scores or single isolated factors. We examined associations of empirically-derived cardiovascular disease risk factor domains with cognition and brain structure. METHODS: 124 adults (age~59.8±13.1;41% African American;50% women) underwent neuropsychological and cardiovascular assessments and structural MRI...
January 16, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28484033/ectopic-protein-interactions-within-brd4-chromatin-complexes-drive-oncogenic-megadomain-formation-in-nut-midline-carcinoma
#3
Artyom A Alekseyenko, Erica M Walsh, Barry M Zee, Tibor Pakozdi, Peter Hsi, Madeleine E Lemieux, Paola Dal Cin, Tan A Ince, Peter V Kharchenko, Mitzi I Kuroda, Christopher A French
To investigate the mechanism that drives dramatic mistargeting of active chromatin in NUT midline carcinoma (NMC), we have identified protein interactions unique to the BRD4-NUT fusion oncoprotein compared with wild-type BRD4. Using cross-linking, affinity purification, and mass spectrometry, we identified the EP300 acetyltransferase as uniquely associated with BRD4 through the NUT fusion in both NMC and non-NMC cell types. We also discovered ZNF532 associated with BRD4-NUT in NMC patient cells but not detectable in 293T cells...
May 8, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28468548/book-review-jennifer-s-singh-multiple-autisms-spectrums-of-advocacy-and-genomic-science-singh-jennifer-s-multiple-autisms-spectrums-of-advocacy-and-genomic-science-university-of-minnesota-press-minneapolis-2016-xv-285-pp-9780816698301-us-94-hbk
#4
https://www.readbyqxmd.com/read/28446150/signatures-of-co-evolutionary-host-pathogen-interactions-in-the-genome-of-the-entomopathogenic-nematode-steinernema-carpocapsae
#5
Mitzi Flores-Ponce, Miguel Vallebueno-Estrada, Eduardo González-Orozco, Hilda E Ramos-Aboites, J Noé García-Chávez, Nelson Simões, Rafael Montiel
BACKGROUND: The entomopathogenic nematode Steinernema carpocapsae has been used worldwide as a biocontrol agent for insect pests, making it an interesting model for understanding parasite-host interactions. Two models propose that these interactions are co-evolutionary processes in such a way that equilibrium is never reached. In one model, known as "arms race", new alleles in relevant genes are fixed in both host and pathogens by directional positive selection, producing recurrent and alternating selective sweeps...
April 26, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28426834/acceptability-of-an-open-label-wait-listed-trial-design-experiences-from-the-proud-prep-study
#6
Mitzy Gafos, Elizabeth Brodnicki, Monica Desai, Sheena McCormack, Will Nutland, Sonali Wayal, Ellen White, Gemma Wood, Tristan Barber, Gill Bell, Amanda Clarke, David Dolling, David Dunn, Julie Fox, Lewis Haddow, Charles Lacey, Anthony Nardone, Killian Quinn, Caroline Rae, Iain Reeves, Michael Rayment, David White, Vanessa Apea, Wilbert Ayap, Claire Dewsnap, Yolanda Collaco-Moraes, Gabriel Schembri, Yinka Sowunmi, Rob Horne
BACKGROUND: PROUD participants were randomly assigned to receive pre-exposure prophylaxis (PrEP) immediately or after a deferred period of one-year. We report on the acceptability of this open-label wait-listed trial design. METHODS: Participants completed an acceptability questionnaire, which included categorical study acceptability data and free-text data on most and least liked aspects of the study. We also conducted in-depth interviews (IDI) with a purposely selected sub-sample of participants...
2017: PloS One
https://www.readbyqxmd.com/read/28425630/earth-abundant-chalcogenide-photovoltaic-devices-with-over-5-efficiency-based-on-a-cu2-basn-s-se-4-absorber
#7
Donghyeop Shin, Tong Zhu, Xuan Huang, Oki Gunawan, Volker Blum, David B Mitzi
In recent years, Cu2 ZnSn(S,Se)4 (CZTSSe) materials have enabled important progress in associated thin-film photovoltaic (PV) technology, while avoiding scarce and/or toxic metals; however, cationic disorder and associated band tailing fundamentally limit device performance. Cu2 BaSnS4 (CBTS) has recently been proposed as a prospective alternative large bandgap (~2 eV), environmentally friendly PV material, with ~2% power conversion efficiency (PCE) already demonstrated in corresponding devices. In this study, a two-step process (i...
April 20, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28420237/intrinsic-instability-of-cs2in-i-m-iii-x6-m-bi-sb-x-halogen-double-perovskites-a-combined-density-functional-theory-and-experimental-study
#8
Zewen Xiao, Ke-Zhao Du, Weiwei Meng, Jianbo Wang, David B Mitzi, Yanfa Yan
Recently, there has been substantial interest in developing double-B-cation halide perovskites, which hold the potential to overcome the toxicity and instability issues inherent within emerging lead halide-based solar absorber materials. Among all double perovskites investigated, In(I)-based Cs2InBiCl6 and Cs2InSbCl6 have been proposed as promising thin-film photovoltaic absorber candidates, with computational examination predicting suitable materials properties, including direct bandgap and small effective masses for both electrons and holes...
April 24, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28358615/semen-collection-and-spermatozoa-characteristics-in-the-kea-parrot-nestor-notabilis
#9
Andrea Dogliero, Ada Rota, Renato Lofiego, Mitzy Mauthe von Degerfeld, Giuseppe Quaranta
We describe the seminal characteristics of the kea parrot (Nestor notabilis), an endangered species endemic to the South Island of New Zealand. Semen was collected in the full breeding season from 6 birds in the collection of an amateur aviculturist. The manual massage technique was used. A total of 25 ejaculates was collected and evaluated for volume, degree of contamination, and spermatozoa concentration; motility and kinetic parameters were assessed on diluted samples (modified Tyrode's Albumin Lactate Pyruvate, pH 8...
March 2017: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/28355358/breast-conserving-surgery-in-locally-advanced-breast-cancer-submitted-to-neoadjuvant-chemotherapy-safety-and-effectiveness-based-on-ipsilateral-breast-tumor-recurrence-and-long-term-follow-up
#10
Guilherme Freire Angotti Carrara, Cristovam Scapulatempo-Neto, Lucas Faria Abrahão-Machado, Maria Mitzi Brentani, João Soares Nunes, Maria Aparecida Azevedo Koike Folgueira, René Aloisio da Costa Vieira
OBJECTIVE: To evaluate ipsilateral breast tumor recurrence after breast-conserving surgery for locally advanced breast cancer. METHODS: A retrospective observational cohort study was performed in patients with locally advanced breast cancer submitted to breast-conserving surgery after neoadjuvant chemotherapy based on an adriamycin-cyclophosphamide-paclitaxel regimen. We evaluated the clinical, pathologic, immunohistochemistry, and surgical factors that contribute to ipsilateral breast tumor recurrence and locoregional recurrence...
March 2017: Clinics
https://www.readbyqxmd.com/read/28350843/high-hiv-prevalence-and-incidence-among-women-in-southern-mozambique-evidence-from-the-mdp-microbicide-feasibility-study
#11
Sibone Mocumbi, Mitzy Gafos, Khatia Munguambe, Ruth Goodall, Sheena McCormack
BACKGROUND: The study aimed to assess the feasibility of conducting large scale HIV prevention clinical trials in Mozambique by measuring HIV prevalence and incidence among women of reproductive age. This paper describes the baseline socio-demographic characteristics of the Mozambique Microbicides Development Programme (MDP) feasibility cohort, baseline prevalence of HIV and other STIs, and HIV incidence. METHODS: The Mozambique MDP feasibility study was conducted from September 2007 to August 2009 in urban Mavalane and rural Manhiça, in Southern Mozambique...
2017: PloS One
https://www.readbyqxmd.com/read/28328972/altered-gut-microbiome-in-a-mouse-model-of-gulf-war-illness-causes-neuroinflammation-and-intestinal-injury-via-leaky-gut-and-tlr4-activation
#12
Firas Alhasson, Suvarthi Das, Ratanesh Seth, Diptadip Dattaroy, Varun Chandrashekaran, Caitlin N Ryan, Luisa S Chan, Traci Testerman, James Burch, Lorne J Hofseth, Ronnie Horner, Mitzi Nagarkatti, Prakash Nagarkatti, Stephen M Lasley, Saurabh Chatterjee
Many of the symptoms of Gulf War Illness (GWI) that include neurological abnormalities, neuroinflammation, chronic fatigue and gastrointestinal disturbances have been traced to Gulf War chemical exposure. Though the association and subsequent evidences are strong, the mechanisms that connect exposure to intestinal and neurological abnormalities remain unclear. Using an established rodent model of Gulf War Illness, we show that chemical exposure caused significant dysbiosis in the gut that included increased abundance of phylum Firmicutes and Tenericutes, and decreased abundance of Bacteroidetes...
2017: PloS One
https://www.readbyqxmd.com/read/28296914/evolutionary-and-natural-history-of-the-turtle-frog-myobatrachus-gouldii-a-bizarre-myobatrachid-frog-in-the-southwestern-australian-biodiversity-hotspot
#13
Samantha Vertucci, Mitzy Pepper, Danielle L Edwards, J Dale Roberts, Nicola Mitchell, J Scott Keogh
Southwest Australia (SWA) is a global biodiversity hotspot and a centre of diversity and endemism for the Australo-Papuan myobatrachid frogs. Myobatrachus gouldii (the turtle frog) has a highly derived morphology associated with its forward burrowing behaviour, largely subterranean habit, and unusual mode of reproduction. Its sister genera Metacrinia and Arenophryne have restricted distributions in Western Australia with significant phylogeographic structure, leading to the recent description of a new species in the latter...
2017: PloS One
https://www.readbyqxmd.com/read/28294478/the-predictive-value-of-dorsal-cingulate-activity-and-fractional-anisotropy-on-long-term-ptsd-symptom-severity
#14
Mitzy Kennis PhD, Sanne J H van Rooij PhD, Alieke Reijnen MSc, Elbert Geuze PhD
BACKGROUND: Posttraumatic stress disorder (PTSD) can be treated with trauma-focused therapy, although only about 50% of the patients recover on the short-term. In order to improve response rates it is important to identify who will and will not recover from trauma-focused therapy. Although previous studies reported dorsal anterior cingulate cortex (ACC) activity, as well as dorsal cingulum bundle white matter microstructure integrity as markers for the persistence of PTSD symptoms on the short-term, it remains unclear whether these markers also predict long-term PTSD symptom severity...
May 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28289286/early-antibody-therapy-can-induce-long-lasting-immunity-to-shiv
#15
Yoshiaki Nishimura, Rajeev Gautam, Tae-Wook Chun, Reza Sadjadpour, Kathryn E Foulds, Masashi Shingai, Florian Klein, Anna Gazumyan, Jovana Golijanin, Mitzi Donaldson, Olivia K Donau, Ronald J Plishka, Alicia Buckler-White, Michael S Seaman, Jeffrey D Lifson, Richard A Koup, Anthony S Fauci, Michel C Nussenzweig, Malcolm A Martin
Highly potent and broadly neutralizing anti-HIV-1 antibodies (bNAbs) have been used to prevent and treat lentivirus infections in humanized mice, macaques, and humans. In immunotherapy experiments, administration of bNAbs to chronically infected animals transiently suppresses virus replication, which invariably returns to pre-treatment levels and results in progression to clinical disease. Here we show that early administration of bNAbs in a macaque simian/human immunodeficiency virus (SHIV) model is associated with very low levels of persistent viraemia, which leads to the establishment of T-cell immunity and resultant long-term infection control...
March 23, 2017: Nature
https://www.readbyqxmd.com/read/28286188/endovascular-repair-of-internal-mammary-artery-aneurysms-in-2-sisters-with-smad3-mutation
#16
Daiva Nevidomskyte, Sherene Shalhub, Gabriel S Aldea, Peter H Byers, Ulrike Schwarze, Mitzi L Murray, Benjamin Starnes
True aneurysms of the internal mammary artery are rare and have been described in association with vasculitis or connective tissue disorders. Herein, we describe 2 cases of familial internal mammary artery aneurysms (IMAs) in 2 sisters with SMAD3 mutation. The older sister presented at the age of 54 years with an incidental diagnosis of a multilobed right IMA and the younger sister presented several years earlier with a ruptured left IMA aneurysm at the age of 49 years. Both sisters had Debakey type I aortic dissections prior to the IMA aneurysm presentation...
March 8, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28285739/neuropsychiatric-comorbidities-in-adults-with-phenylketonuria-a-retrospective-cohort-study
#17
Deborah A Bilder, Joyce A Kobori, Jessica L Cohen-Pfeffer, Erin M Johnson, Elaina R Jurecki, Mitzie L Grant
Adults with phenylketonuria (PKU) may experience neurologic and psychiatric disorders, including intellectual disability, anxiety, depression, and neurocognitive dysfunction. Identifying the prevalence and prevalence ratios of these conditions will inform clinical treatment. This nested, case-controlled study used International Classification of Diseases, Ninth Revision (ICD-9) codes from the MarketScan® insurance claims databases from 2006 to 2012 and healthcare claims data for US-based employer and government-sponsored health plans...
March 6, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/28284221/uptake-of-hormonal-contraceptives-and-correlates-of-uptake-in-a-phase-iii-clinical-trial-in-rural-south-western-uganda
#18
RANDOMIZED CONTROLLED TRIAL
Andrew Abaasa, Mitzy Gafos, Zacchaeus Anywaine, Andrew Nunn, Angela Crook, Jonathan Levin, Sheena McCormack, Anatoli Kamali
BACKGROUND: Use of a reliable contraception method has become an inclusion criterion in prevention trials to minimize time off product. We report on hormonal contraceptive prevalence, uptake, sustained use and correlates of use in the Microbicides Development Programme (MDP 301) trial at the Masaka Centre in Uganda. METHODS: HIV negative women in sero-discordant relationships were enrolled and followed-up for 52 to 104 weeks from 2005 to 2009. Contraceptive use data was collected through self-report at baseline and dispensing records during follow-up...
March 11, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28252487/investigating-and-prioritizing-educational-opportunities
#19
Mitzi Grey
No abstract text is available yet for this article.
March 2017: Journal for Nurses in Professional Development
https://www.readbyqxmd.com/read/28168424/characterization-of-dysregulated-mirna-in-peripheral-blood-mononuclear-cells-from-ischemic-stroke-patients
#20
Marpe Bam, Xiaoming Yang, Souvik Sen, Elizabeth E Zumbrun, Lauren Dennis, Jiajia Zhang, Prakash S Nagarkatti, Mitzi Nagarkatti
Epigenetic modification may play an important role in pathophysiology of ischemic stroke (IS) risk. MicroRNAs (miRNAs), which constitute one of the modes of epigenetic regulation, have been shown to be associated with a number of clinical disorders including IS. The purpose of this study was to investigate the miRNA profile in the peripheral blood mononuclear cells (PBMCs) of IS patients and compare it with stroke-free controls. Blood samples were obtained from 19 healthy age-gender-race matched individuals who served as controls to 20 IS patients...
February 6, 2017: Molecular Neurobiology
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