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https://www.readbyqxmd.com/read/29767565/medical-management-of-deep-ulcerative-keratitis-in-cats-13-cases
#1
Michelle G Martin de Bustamante, Kathryn L Good, Brian C Leonard, Steven R Hollingsworth, Sydney G Edwards, Kelly E Knickelbein, Ann E Cooper, Sara M Thomasy, David J Maggs
Case series summary Described are 13 cats diagnosed with deep ulcerative keratitis and successfully managed medically without grafting procedures. Typical treatment involved frequent topical application of serum and antibiotics (usually a fluoroquinolone and a cephalosporin). Seven cats also received systemic antibiotics. Analgesia was achieved using various combinations of topical atropine and systemic buprenorphine, robenacoxib or corticosteroids. Six cats were hospitalized for a median (range) period of 2...
May 1, 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29766142/improving-life-expectancy-a-broken-neck-doesn-t-have-to-be-a-terminal-diagnosis-for-the-elderly
#2
Laura N Godat, Leslie M Kobayashi, David C Chang, Raul Coimbra
Background: Elderly patients with cervical spine fractures require optimal care. Treatment with a cervical collar or halo instead of surgical fixation may increase mortality. This investigation intends to describe the life expectancy after injury and evaluate the impact of surgical intervention on mortality. Methods: Patients ≥65 years, with traumatic cervical spine fractures without cord injury were identified in the 1995-2009 California Office of Statewide Health and Planning database...
2018: Trauma surgery & acute care open
https://www.readbyqxmd.com/read/29759378/recombinant-m-bovis-bcg-expressing-the-pld-protein-promotes-survival-in-mice-challenged-with-a-c-pseudotuberculosis-virulent-strain
#3
Karen Silva Leal, Mara Thais de Oliveira Silva, Andréa de Fátima Silva Rezende, Francisco Silvestre Brilhante Bezerra, Karine Begnini, Fabiana Seixas, Tiago Collares, Odir Dellagostin, Ricardo Wagner Portela, Vasco Ariston de Carvalho Azevedo, Sibele Borsuk
The aim of this study was to evaluate the survival of mice inoculated with M. bovis BCG Pasteur recombinant expressing the PLD protein and challenged with a C. pseudotuberculosis virulent strain. Four groups were immunized with a sterile 0.9% saline solution (G1), 106  CFU of M. bovis BCG Pasteur (G2), 106  CFU of M. bovis BCG/pld (G3) or 106  CFU of M. bovis BCG/pld with a booster with rPLD (G4) and challenged with 104 CFU of C. pseudotuberculosis MIC-6 strain. The highest survival rate of 88% was observed in G4, followed by 77% in G3 and 66% in G2...
May 11, 2018: Vaccine
https://www.readbyqxmd.com/read/29757965/nutrition-of-six-selected-neo-tropical-mammals-in-trinidad-and-tobago-with-the-potential-for-domestication
#4
REVIEW
Kavita Ranjeeta Lall, Kegan Romelle Jones, Gary Wayne Garcia
This review highlights the available literature on the nutrition of six neo-tropical animals with the potential for domestication-the agouti ( Dasyprocta leporina / D. aguti ), lappe ( Agouti paca ), capybara ( Hydrochoerus hydrochaeris ), manicou/opossum ( Didelphis marsupialis insularis ), collared peccary ( Peccary tajucu ) and the red brokcet deer ( Mazama americana ). Over 100 references were used, spanning over 100 years. The earliest being 1915 and the most recent being 2018. The references used in this review were synthesized to give a detailed look of the dentition, anatomy of the gastrointestinal tract and type of feed these animals consume...
May 14, 2018: Veterinary Sciences
https://www.readbyqxmd.com/read/29741769/contrasting-seasonal-and-aseasonal-environments-across-stages-of-the-annual-cycle-in-the-rufous-collared-sparrow-zonotrichia-capensis-differences-in-endocrine-function-proteome-and-body-condition
#5
Paulina L González-Gómez, Valentina Echeverria, Cristian F Estades, Jonathan H Perez, Jesse S Krause, Pablo Sabat, Jonathon Li, Dietmar Kültz, John C Wingfield
1.The timing and duration of life history stages (LHS) within the annual cycle can be affected by local environmental cues which are integrated through endocrine signaling mechanisms and changes in protein function. Most animals express a single LHS within a given period of the year because synchronous expression of LHSs is thought to be too costly energetically. However, in very rare and extremely stable conditions, breeding and molt have been observed to overlap extensively in Rufous-collared sparrows (Zonotrichia capensis) living in valleys of the Atacama Desert - one of the most stable and aseasonal environments on Earth...
May 9, 2018: Journal of Animal Ecology
https://www.readbyqxmd.com/read/29726286/risk-of-subsidence-and-peri-prosthetic-fractures-using-collared-hydroxyapatite-coated-stem-for-hip-arthroplasty-in-the-elderly
#6
Farhan Syed, Amr Hussein, Krishnaiah Katam, Paul Saunders, Stephen K Young, Mohammad Faisal
INTRODUCTION: Subsidence has been noted with both cemented and uncemented stems in hip arthroplasty. On most occasions, it's minimal (i.e. less than 2 mm) and stabilises at 1 year. However, when its progressive and significant, it causes loss of length and horizontal offset, and when symptomatic warrants a revision. Patients/Materials & Methods: A retrospective radiological review of the patient database was carried out to identify all patients with age ≥ 70 years who underwent elective hip arthroplasty using uncemented HA coated collared stem and had radiographs at 1 year follow up...
May 1, 2018: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29708774/environmental-factors-related-to-a-semiarid-climate-influence-the-freezability-of-sperm-from-collared-peccaries-pecari-tajacu-linnaeus-1758
#7
Keilla M Maia, Ana L P Souza, Erica C G Praxedes, Luana G P Bezerra, Andreia M Silva, Livia B Campos, Samara S J Moreira, Carlos A C Apolinário, João B F Souza, Alexandre R Silva
The influence of environmental factors in a semiarid climate on characteristics of fresh and frozen/thawed sperm collected from collared peccaries (Pecari tajacu) was assessed. Semen from 11 male collared peccaries was collected by electroejaculation during the peaks of the dry and rainy periods while rainfall indices, air temperatures, relative humidity levels, and wind speeds were measured. The number, motility, morphology, osmotic response, and membrane integrity of sperm in the collected ejaculates were assessed...
April 30, 2018: Biopreservation and Biobanking
https://www.readbyqxmd.com/read/29705652/nonoperative-management-of-c-2-dens-fractures-single-center-experience-and-review-of-the-literature
#8
Oliver Gembruch, Elias Lemonas, Yahya Ahmadipour, Ulrich Sure, Nicolai El Hindy, Oliver Müller
OBJECTIVE: The demographic change in the population leads to a rising number of patients presenting with fractures of the cervical spine, especially C-2, due to falls. With an increase of co-morbidities in these elder patients, the risk for intra- and postoperative complications is increased likewise. Thus, an alternative strategy instead of operative management of these fractures should be taken into account whenever possible. Conservative management of dens fractures in the elderly is still a subject of great controversy despite numerous studies on this topic...
April 22, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29694188/search-for-neutrinoless-double-%C3%AE-decay-in-76-ge-with-the-majorana-demonstrator
#9
C E Aalseth, N Abgrall, E Aguayo, S I Alvis, M Amman, I J Arnquist, F T Avignone, H O Back, A S Barabash, P S Barbeau, C J Barton, P J Barton, F E Bertrand, T Bode, B Bos, M Boswell, A W Bradley, R L Brodzinski, V Brudanin, M Busch, M Buuck, A S Caldwell, T S Caldwell, Y-D Chan, C D Christofferson, P-H Chu, J I Collar, D C Combs, R J Cooper, C Cuesta, J A Detwiler, P J Doe, J A Dunmore, Yu Efremenko, H Ejiri, S R Elliott, J E Fast, P Finnerty, F M Fraenkle, Z Fu, B K Fujikawa, E Fuller, A Galindo-Uribarri, V M Gehman, T Gilliss, G K Giovanetti, J Goett, M P Green, J Gruszko, I S Guinn, V E Guiseppe, A L Hallin, C R Haufe, L Hehn, R Henning, E W Hoppe, T W Hossbach, M A Howe, B R Jasinski, R A Johnson, K J Keeter, J D Kephart, M F Kidd, A Knecht, S I Konovalov, R T Kouzes, B D LaFerriere, J Leon, K T Lesko, L E Leviner, J C Loach, A M Lopez, P N Luke, J MacMullin, S MacMullin, M G Marino, R D Martin, R Massarczyk, A B McDonald, D-M Mei, S J Meijer, J H Merriman, S Mertens, H S Miley, M L Miller, J Myslik, J L Orrell, C O'Shaughnessy, G Othman, N R Overman, G Perumpilly, W Pettus, D G Phillips, A W P Poon, K Pushkin, D C Radford, J Rager, J H Reeves, A L Reine, K Rielage, R G H Robertson, M C Ronquest, N W Ruof, A G Schubert, B Shanks, M Shirchenko, K J Snavely, N Snyder, D Steele, A M Suriano, D Tedeschi, W Tornow, J E Trimble, R L Varner, S Vasilyev, K Vetter, K Vorren, B R White, J F Wilkerson, C Wiseman, W Xu, E Yakushev, H Yaver, A R Young, C-H Yu, V Yumatov, I Zhitnikov, B X Zhu, S Zimmermann
The Majorana Collaboration is operating an array of high purity Ge detectors to search for neutrinoless double-β decay in ^{76}Ge. The Majorana Demonstrator comprises 44.1 kg of Ge detectors (29.7 kg enriched in ^{76}Ge) split between two modules contained in a low background shield at the Sanford Underground Research Facility in Lead, South Dakota. Here we present results from data taken during construction, commissioning, and the start of full operations. We achieve unprecedented energy resolution of 2...
March 30, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29680288/involvement-of-methoprene-tolerant-met-in-the-determination-of-the-final-body-size-in-leptinotarsa-decemlineata-say-larvae
#10
Qing-Wei Meng, Qing-Yu Xu, Pan Deng, Kai-Yun Fu, Wen-Chao Guo, Guo-Qing Li
In the tobacco hornworm Manduca sexta, juvenile hormone (JH) is critical for the control of species-specific size. However, whether the basic helix-loop-helix/Per-Arnt-Sim domain receptor methoprene-tolerant (Met) is involved remains unconfirmed. In the present paper, we found that RNA interference (RNAi)-aided knockdown of Met gene (LdMet) lowered the larval and pupal fresh weights and shortened the larval development period in the Colorado potato beetle Leptinotarsa decemlineata. Dietary introduction of JH into the LdMet RNAi larvae rescued neither the decreased weights nor the reduced development phase, even though JH ingestion by control larvae extended developmental time and caused large pupae...
April 19, 2018: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29673854/silencing-of-non-pou-domain-containing-octamer-binding-protein-stabilizes-atherosclerotic-plaque-in-apolipoprotein-e-knockout-mice-via-nf-%C3%AE%C2%BAb-signaling-pathway
#11
Kai Zhang, Fang Zhang, Jian-Min Yang, Jing Kong, Xiao Meng, Meng Zhang, Cheng Zhang, Yun Zhang
BACKGROUND: It remains unknown whether Non-POU-domain-containing octamer-binding protein (NonO) plays a causative role in plaque destabilization. We hypothesized that NonO gene silencing may stabilize atherosclerotic plaque by increasing P4Hα1 expression and inhibiting the inflammation. METHODS AND RESULTS: Vulnerable atherosclerotic plaques were induced in ApoE-/- mice by high fat diet, perivascular collar placement and mental stress. Compared with normal carotid arteries, those contained vulnerable plaques had high NonO expression...
April 7, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29651680/simultaneous-identification-and-determination-of-flavonoids-in-dendrobium-officinale
#12
Chunhua Zhou, Zhenshan Xie, Zhouxi Lei, Yuechun Huang, Gang Wei
BACKGROUND: The quality of material medicine resources has had a considerable impact on the development of the health industry, which has created a bottleneck for traditional Chinese medicine (TCM). Dendrobium officinale, which has been widely used for health prevention in TCM, has become a high-nutritive health food that is strongly recommended by many white-collar workers and people who pay more attention to their health. The aim of this study was to develop a method to authenticate and evaluate D...
April 12, 2018: Chemistry Central Journal
https://www.readbyqxmd.com/read/29651626/current-topics-in-the-management-of-acute-traumatic-spinal-cord-injury
#13
Christopher D Shank, Beverly C Walters, Mark N Hadley
Acute traumatic spinal cord injury (SCI) affects more than 250,000 people in the USA, with approximately 17,000 new cases each year. It continues to be one of the most significant causes of trauma-related morbidity and mortality. Despite the introduction of primary injury prevention education and vehicle safety devices, such as airbags and passive restraint systems, traumatic SCI continues to have a substantial impact on the healthcare system. Over the last three decades, there have been considerable advancements in the management of patients with traumatic SCI...
April 12, 2018: Neurocritical Care
https://www.readbyqxmd.com/read/29649479/a-spherical-aberration-free-microscopy-system-for-live-brain-imaging
#14
Yoshihiro Ue, Hiromu Monai, Kaori Higuchi, Daisuke Nishiwaki, Tetsuya Tajima, Kenya Okazaki, Hiroshi Hama, Hajime Hirase, Atsushi Miyawaki
The high-resolution in vivo imaging of mouse brain for quantitative analysis of fine structures, such as dendritic spines, requires objectives with high numerical apertures (NAs) and long working distances (WDs). However, this imaging approach is often hampered by spherical aberration (SA) that results from the mismatch of refractive indices in the optical path and becomes more severe with increasing depth of target from the brain surface. Whereas a revolving objective correction collar has been designed to compensate SA, its adjustment requires manual operation and is inevitably accompanied by considerable focal shift, making it difficult to acquire the best image of a given fluorescent object...
April 9, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29624855/evaluation-of-movement-behaviors-to-inform-toxic-baiting-strategies-for-invasive-wild-pigs-sus-scrofa
#15
Michael J Lavelle, Nathan P Snow, Joseph M Halseth, Eric H VanNatta, Heather N Sanders, Kurt C VerCauteren
BACKGROUND: Invasive wild pigs damage agriculture, property, and natural ecosystems. To curtail damage, an effective and humane toxic bait containing microencapsulated sodium nitrite is under development. Strategies for delivering the toxic bait are needed to establish adequate spacing of bait sites, and for simultaneously accustoming wild pigs to the novel bait and wild pig-specific bait stations designed to exclude non-target species. RESULTS: We monitored movements of 32 GPS collared wild pigs relative to 41 bait sites containing placebo bait...
April 6, 2018: Pest Management Science
https://www.readbyqxmd.com/read/29614604/-effect-of-nutrition-quality-of-breakfast-on-satiety-among-young-white-collar-workers
#16
Z C Tang, A L Liu, Y Zhao, D C Luan, C Song, H Zeng, L L Han, G S Ma
Objective: To analyze the effect of breakfast nutrition quality on the satiety among young white-collar workers. Methods: A total of 278 subjects were recruited from two cities, Shenyang and Chongqing, in June 2015. The inclusion criteria: white-collar workers aged 25-45 years involved mainly in office work, who did not experience major changes, and individuals who should follow the study protocol and sign the informed consent form. The study employed a three-phase crossover design trial. Each participant received nutritional-adequate breakfast, nutritional-inadequate breakfast, and no breakfast treatment on the basis of assignment to one of three sequences...
April 6, 2018: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29610711/determining-the-numbers-of-a-landscape-architect-species-tapirus-terrestris-using-footprints
#17
Danielle O Moreira, Sky K Alibhai, Zoe C Jewell, Cristina J da Cunha, Jardel B Seibert, Andressa Gatti
Background: As a landscape architect and a major seed disperser, the lowland tapir ( Tapirus terrestris ) is an important indicator of the ecological health of certain habitats. Therefore, reliable data regarding tapir populations are fundamental in understanding ecosystem dynamics, including those associated with the Atlantic Forest in Brazil. Currently, many population monitoring studies use invasive tagging with radio or satellite/Global Positioning System (GPS) collars. These techniques can be costly and unreliable, and the immobilization required carries physiological risks that are undesirable particularly for threatened and elusive species such as the lowland tapir...
2018: PeerJ
https://www.readbyqxmd.com/read/29609648/six-helix-bundle-completion-in-the-distal-c-terminal-heptad-repeat-region-of-gp41-is-required-for-efficient-human-immunodeficiency-virus-type-1-infection
#18
Dehua Liu, Hongyun Wang, Mizuki Yamamoto, Jiping Song, Rui Zhang, Qingling Du, Yasushi Kawaguchi, Jun-Ichiro Inoue, Zene Matsuda
BACKGROUND: The native pre-fusion structure of gp120/gp41 complex of human immunodeficiency virus type 1 was recently revealed. In the model, the helices of gp41 (α6, α7, α8, and α9) form a four-helix collar underneath trimeric gp120. Gp41 is a class I fusion protein and mediates membrane fusion by forming a post-fusion structure called the six-helix bundle (6HB). The comparison of the pre- and post-fusion structures revealed the large conformational changes in gp41 during the antiparallel packing of the N- and C-terminal heptad repeats (NHRs and CHRs) in membrane fusion...
April 2, 2018: Retrovirology
https://www.readbyqxmd.com/read/29588621/investigating-the-effects-of-cervical-collar-design-and-fit-on-the-biomechanical-and-biomarker-reaction-at-the-skin
#19
Peter R Worsley, Nathan D Stanger, Aran K Horrell, Dan L Bader
Background: Research has shown that up to 33% of pressure ulcers (PUs) acquired in hospitals result from the application of a medical device. Cervical collars (C-collars) have been implicated in causing PUs, due to the mechanical force they apply to the skin. In order to improve our understanding of collar-related PUs, the present study aimed to assess the biomechanical, biochemical, and microclimate effects of C-collar design and fitting tension. Methods: A cohort of 15 healthy volunteers was fit with two different C-collars according to the manufacturer guidelines...
2018: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/29551502/microcystin-induction-small-maf-protein-involve-in-transcriptional-regulation-of-gst-from-freshwater-mussel-cristaria-plicata
#20
Xiaobo Wang, Jielian Wu, Shaoqing Jian, Gang Yang, Baoqing Hu, Chungen Wen
The small Mafs, MafF, MafG and MafK play critical roles in morphogenesis and homeostasis through associating with Cap "n" Collar family of transcription factors. In this study, we tried to identify a small Maf protein in the freshwater mussel Cristaria plicata. The MafK cDNA of C. plicata, designated as CpMafK, was cloned from the hemocytes using degenerate primers by the rapid amplification of cDNA ends PCR. The full length cDNA of CpMafK is 2170 bp, which includes an open reading frame of 570 bp, encoding 190 amino acids...
March 15, 2018: Gene
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