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https://www.readbyqxmd.com/read/28719384/anesthetic-management-of-an-infant-with-postnatally-diagnosed-tracheal-agenesis-undergoing-tracheal-reconstruction-a-case-report
#1
Brittany L Willer, Kayla G Bryan, Daiva E Parakininkas, Michael R Uhing, Susan R Staudt, Kathleen M Dominguez, Michael E McCormick, Michael E Mitchell, John C Densmore, Keith T Oldham, Richard J Berens
A term infant born cyanotic failed multiple intubation attempts and tracheostomy placement. After esophageal intubation resulted in the ability to ventilate, he was presumed to have tracheal agenesis and distal bronchoesophageal fistula. He was transferred to our institution where he was diagnosed with Floyd Type II tracheal agenesis. He underwent staged tracheal reconstruction. He was discharged to home at 4 months of age with a tracheostomy collar, cervical spit fistula, and gastrostomy tube. He represents the sole survivor-to-discharge of tracheal agenesis in the United States...
July 17, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28696731/dark-matter-search-results-from-the-pico-60%C3%A2-c_-3-f_-8-bubble-chamber
#2
C Amole, M Ardid, I J Arnquist, D M Asner, D Baxter, E Behnke, P Bhattacharjee, H Borsodi, M Bou-Cabo, P Campion, G Cao, C J Chen, U Chowdhury, K Clark, J I Collar, P S Cooper, M Crisler, G Crowder, C E Dahl, M Das, S Fallows, J Farine, I Felis, R Filgas, F Girard, G Giroux, J Hall, O Harris, E W Hoppe, M Jin, C B Krauss, M Laurin, I Lawson, A Leblanc, I Levine, W H Lippincott, F Mamedov, D Maurya, P Mitra, T Nania, R Neilson, A J Noble, S Olson, A Ortega, A Plante, R Podviyanuk, S Priya, A E Robinson, A Roeder, R Rucinski, O Scallon, S Seth, A Sonnenschein, N Starinski, I Štekl, F Tardif, E Vázquez-Jáuregui, J Wells, U Wichoski, Y Yan, V Zacek, J Zhang
New results are reported from the operation of the PICO-60 dark matter detector, a bubble chamber filled with 52 kg of C_{3}F_{8} located in the SNOLAB underground laboratory. As in previous PICO bubble chambers, PICO-60 C_{3}F_{8} exhibits excellent electron recoil and alpha decay rejection, and the observed multiple-scattering neutron rate indicates a single-scatter neutron background of less than one event per month. A blind analysis of an efficiency-corrected 1167-kg day exposure at a 3.3-keV thermodynamic threshold reveals no single-scattering nuclear recoil candidates, consistent with the predicted background...
June 23, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28691432/effect-of-diode-lasers-with-wavelength-of-445-and-980-nm-on-a-temperature-rise-when-uncovering-implants-for-second-stage-surgery-an-ex-vivo-study-in-pigs
#3
Jacek Matys, Rafał Flieger, Marzena Dominiak
BACKGROUND: Many surgical procedures in a soft tissue are performed using diodes lasers. Recently, a novel diode laser operates in 445 nm wavelength was introduced in dentistry. OBJECTIVES: The aim of our study was to evaluate a time of surgery and an increase in temperature of a titanium implants during its uncovering using 445 and 980 nm wavelengths. MATERIAL AND METHODS: The research included 45 pig mandibles (n=45). The specimens were randomly divided into 3 groups (n=15) according to the laser irradiation mode and wavelength; G1 - 445nm laser, power: 3 W, continuous wave (CW), distance: 2 mm, power density: 7460 W/cm2, fiber: 320µm, none-contact mode; G2 - 445nm laser (power: 2 W, CW, power density: 4970 W/cm2, fiber: 320µm, contact mode; G3 (control) - 980nm laser, power: 2...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28684013/cervical-spine-alignment-in-helmeted-skiers-and-snowboarders-with-suspected-head-and-neck-injuries-comparison-of-lateral-c-spine-radiographs-before-and-after-helmet-removal-and-implications-for-ski-patrol-transport
#4
Jared Murray, David A Rust
OBJECTIVE: Current protocols for spine immobilization of the injured skier/snowboarder have not been scientifically validated. Observing changes in spine alignment during common rescue scenarios will help strengthen recommendations for rescue guidelines. METHODS: Twenty-eight healthy volunteers (18 men, 10 women) age 47±17 (range 20-73) (mean ±SD with range) underwent a mock rescue in which candidate patrollers completing an Outdoor Emergency Care course performed spine immobilization and back boarding in 3 scenarios: 1) Ski helmet on, no c-collar; 2) helmet on, with c-collar; and 3) helmet removed, with c-collar...
July 3, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28674083/combining-local-immunotoxins-targeting-mesothelin-with-ctla-4-blockade-synergistically-eradicates-murine-cancer-by-promoting-anti-cancer-immunity
#5
Yasmin Leshem, James O'Brien, Xiufen Liu, Tapan K Bera, Masaki Terabe, Jay A Berzofsky, Birgit Bossenmaier, Gerhard Niederfellner, Chin-Hsien Tai, Yoram Reiter, Ira Pastan
Immune checkpoint blockade using antibodies to cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) benefits a limited number of cancer patients. SS1P and LMB-100 are immunotoxins that target mesothelin. We observed delayed responses to SS1P in patients with mesothelioma suggesting that anti-tumor immunity was induced. Our goal was to stimulate anti-tumor immunity by combining SS1P or LMB-100 with anti-CTLA-4. We constructed a BALB/c breast cancer cell line expressing human mesothelin (66C14-M) which was implanted in one or two locations...
July 3, 2017: Cancer Immunology Research
https://www.readbyqxmd.com/read/28667107/the-two-cryptochrome-photolyase-family-proteins-fulfill-distinct-roles-in-dna-photorepair-and-regulation-of-conidiation-in-the-gray-mold-fungus-botrytis-cinerea
#6
Kim C Cohrs, Julia Schumacher
The plant pathogenic Leotiomycete Botrytis cinerea is known for the strict regulation of its asexual differentiation programs by the environmental light conditions. Sclerotia are formed in constant darkness, black/near-UV (NUV) light induces conidiation and blue light represses both differentiation programs. Sensing of black/NUV light is attributed to proteins of the cryptochrome/photolyase family (CPF). To elucidate the molecular basis of the photoinduction of conidiation, we functionally characterized the two CPF proteins encoded in the genome of B...
June 30, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28665777/longevity-of-anterior-composite-restorations-in-a-general-dental-practice-based-network
#7
K Collares, N J M Opdam, M Laske, E M Bronkhorst, F F Demarco, M B Correa, M C D N J M Huysmans
This practice-based study investigated the performance of a large set of anterior composite restorations placed by a group of 24 general practices. Based on data from electronic patient files, the longevity of 72,196 composite restorations was analyzed, as placed in 29,855 patients by 47 general dental practitioners between 1996 and 2011. Annual failure rates (AFRs) were calculated, and variables associated with failure were assessed by multivariate Cox regression analysis with shared frailty for 2 age groups (5 to 24 y and ≥25 y)...
June 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28665242/changes-in-use-of-cervical-spine-magnetic-resonance-imaging-for-pediatric-patients-with-nonaccidental-trauma
#8
Ahyuda Oh, Michael Sawvel, David Heaner, Amina Bhatia, Andrew Reisner, R Shane Tubbs, Joshua J Chern
OBJECTIVE Past studies have suggested correlations between abusive head trauma and concurrent cervical spine (c-spine) injury. Accordingly, c-spine MRI (cMRI) has been increasingly used in radiographic assessments. This study aimed to determine trends in cMRI use and treatment, and outcomes related to c-spine injury in children with nonaccidental trauma (NAT). METHODS A total of 503 patients with NAT who were treated between 2009 and 2014 at a single pediatric health care system were identified from a prospectively maintained database...
June 30, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28650725/exposure-to-benzene-in-a-pooled-analysis-of-petroleum-industry-case-control-studies
#9
D C Glass, A R Schnatter, G Tang, T W Armstrong, L Rushton
Cases of lymphohematopoietic cancer from three petroleum industry cohorts, matched to controls from the respective cohort, were pooled into single study. Average benzene exposure was quantitatively estimated in ppm for each job based on measured data from the relevant country, adjusted for the specific time period, site and job exposure characteristics and the certainty of the exposure estimate scored. The probability of dermal exposure and of peak exposure was also assessed. Before risk was examined, an exposure estimate comparison and rationalisation exercise was performed across the studies to ensure accuracy and consistency of approach...
June 26, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28648410/the-great-unknown-a-systematic-literature-review-about-risk-associated-with-intraoperative-imaging-during-orthopaedic-surgeries
#10
REVIEW
Amir Matityahu, Ryan K Duffy, Sabine Goldhahn, Alexander Joeris, Peter H Richter, Florian Gebhard
INTRODUCTION: Modern techniques in orthopaedic surgery using minimally invasive procedures, and increased use of fluoroscopic imaging present a potential increased risk to surgeons due to ionizing radiation exposure. This article is a systematic review of recent literature on radiation exposure of orthopaedic surgeons. MATERIALS AND METHODS: Pubmed and Cochrane searches were performed on intraoperative radiation exposure covering English and German articles published between 1...
April 21, 2017: Injury
https://www.readbyqxmd.com/read/28647656/delayed-retroclival-and-cervical-spinal-subdural-hematoma-complicated-by-pre-existing-chiari-malformation-in-an-adult-trauma-patient
#11
Ha Nguyen, Hoon Choi, Shekar Kurpad, Hesham Soliman
INTRODUCTION: Traumatic spinal subdural hematoma involving the retroclival region and upper cervical spine is a rare pathology. To our knowledge, there have only been two prior cases in an adult trauma patient. We describe a patient with pre-existing Chiari 1 malformation, who recently sustained a unilateral Type 1 OCF (occipital condyle fracture) with associated disruption of the tectorial membrane and transverse ligament, that returned with a retroclival subdural hematoma extending down to C7, causing spinal cord compression and symptomatic obstructive hydrocephalus...
June 21, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28639611/masked-hypertension-and-effort-reward-imbalance-at-work-among-2369-white-collar-workers
#12
P Boucher, M Gilbert-Ouimet, X Trudel, C S Duchaine, A Milot, C Brisson
Hypertension is an important risk factor of cardiovascular diseases, the leading cause of death worldwide. Adverse effects of psychosocial factors at work might increase the risk of masked hypertension, but evidences are still scarce. The objective of this study is then to determine whether adverse psychosocial work factors from the effort-reward imbalance (ERI) model are associated with the prevalence of masked hypertension in a population of white-collar workers. White-collar workers were recruited from three public organizations...
June 22, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28629605/ct-findings-in-11-patients-with-tafro-syndrome-a-variant-of-multicentric-castleman-s-disease
#13
T Kiguchi, C Sato, K Takai, Y Nakai, Y Kaneko, M Matsuki
AIM: To assess detailed computed tomography (CT) findings in patients with the recently described thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly (TAFRO) syndrome, in order to contribute to imaging interpretation in the challenging diagnosis of this disease. MATERIALS AND METHODS: The institutional review board approved this retrospective study and waived the need for informed consent. Eleven patients (six men, five women; mean age, 52.5 years) with confirmed TAFRO syndrome were included in this study...
June 16, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28623602/protein-requirements-of-collared-peccary-pecari-tajacu
#14
Rogério M Borges, Alcester Mendes, Selene S C Nogueira, Jérôme Bindelle, Sérgio L G Nogueira-Filho
A nitrogen (N) balance digestion trial was conducted to determine the protein requirement of collared peccaries (Pecari tajacu). In a 4 × 4 Latin square design, four captive adult male peccaries were fed four isoenergy diets containing four different levels of N (11.7, 16.3, 22.8, and 26.7 g N/kg of dry matter-DM). After 15 days of adaptation, a total collection of feces and urine was carried out for five consecutive days. Regression analyses between N intake and N in feces and urine allowed to calculate the metabolic fecal nitrogen (MFN = 2...
June 16, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28614151/success-rate-of-variable-collar-size-frosted-jones-tubes
#15
C Blake Perry, Roger A Dailey
PURPOSE: To describe success rates and long-term outcomes of conjunctivodacryocystorhinostomy (CDCR) with larger collar (4.5 or 5.0 mm) frosted Jones tubes (FJTs). METHODS: A retrospective chart review of all patients who received a larger collar (4.5 or 5.0 mm) FJT following CDCR by an author (RAD) was performed between January 1, 2010 and July 1, 2016. Patient demographics, etiology of tearing, follow-up time from placement of larger collar FJT, original tube collar diameter, number and sizes of collar adjustments, tearing status, and complications were recorded...
June 13, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28613280/insights-into-the-genetic-architecture-of-morphological-traits-in-two-passerine-bird-species
#16
C N S Silva, S E McFarlane, I J Hagen, L Rönnegård, A M Billing, T Kvalnes, P Kemppainen, B Rønning, T H Ringsby, B-E Sæther, A Qvarnström, H Ellegren, H Jensen, A Husby
Knowledge about the underlying genetic architecture of phenotypic traits is needed to understand and predict evolutionary dynamics. The number of causal loci, magnitude of the effects and location in the genome are, however, still largely unknown. Here, we use genome-wide single-nucleotide polymorphism (SNP) data from two large-scale data sets on house sparrows and collared flycatchers to examine the genetic architecture of different morphological traits (tarsus length, wing length, body mass, bill depth, bill length, total and visible badge size and white wing patches)...
June 14, 2017: Heredity
https://www.readbyqxmd.com/read/28611605/different-roles-for-honey-bee-mushroom-bodies-and-central-complex-in-visual-learning-of-colored-lights-in-an-aversive-conditioning-assay
#17
Jenny A Plath, Brian V Entler, Nicholas H Kirkerud, Ulrike Schlegel, C Giovanni Galizia, Andrew B Barron
The honey bee is an excellent visual learner, but we know little about how and why it performs so well, or how visual information is learned by the bee brain. Here we examined the different roles of two key integrative regions of the brain in visual learning: the mushroom bodies and the central complex. We tested bees' learning performance in a new assay of color learning that used electric shock as punishment. In this assay a light field was paired with electric shock. The other half of the conditioning chamber was illuminated with light of a different wavelength and not paired with shocks...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28598130/-radiation-dose-of-body-surface-at-sensitive-organs-and-its-protective-precaution-in-head-ct-scanning-initial-experience
#18
Chun-Chao Xia, Jin Pu, Lei Li, Fei Zhao, Kai Zhang, Yu-Ming Li, Wan-Lin Peng, Jin-Ge Zhang, Zhen-Lin Li
OBJECTIVES: To investigate the radiation dose of body surface at sensitive organs using different protective precaution in head CT scanning. METHODS: The standard phantom received head routine sequence scanning with dual-source computed tomography.The phantoms were scanned with three different protective precaution:group A (without protective clothing),group B (wearing lead collar and cover lead clothes),group C (wearing lead collar and clothes without cuffs).The thermoluminescence dosimeters (TLD) was placed on the body surface corresponding to sensitive organs to measure radiation dose...
November 2016: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28596375/nlrp3-inflammasome-inhibition-by-mcc950-reduces-atherosclerotic-lesion-development-in-apolipoprotein-e-deficient-mice
#19
Thomas van der Heijden, Eva Kritikou, Wouter Venema, Janine van Duijn, Peter J van Santbrink, Bram Slütter, Amanda C Foks, Ilze Bot, Johan Kuiper
OBJECTIVE: Inflammasomes are multiprotein complexes, and their activation has been associated with cardiovascular disease. Inflammasome activation leads to secretion of caspase-1 by innate immune cells, resulting in the activation of interleukin-1β. Recently, a potent and selective inhibitor of the NLRP3 inflammasome, MCC950, was described. In this study, we investigated the effect of MCC950 on atherosclerotic lesion development in apoE(-/-) mice. APPROACH AND RESULTS: First, we determined the efficacy of MCC950 in vitro...
June 8, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/28573721/gps-identified-low-level-nocturnal-activity-of-vervets-chlorocebus-pygerythrus-and-olive-baboons-papio-anubis-in-laikipia-kenya
#20
Lynne A Isbell, Laura R Bidner, Margaret C Crofoot, Akiko Matsumoto-Oda, Damien R Farine
OBJECTIVES: Except for owl monkeys (Aotus spp.), all anthropoid primates are considered strictly diurnal. Recent studies leveraging new technologies have shown, however, that some diurnal anthropoids also engage in nocturnal activity. Here we examine the extent to which vervets (Chlorocebus pygerythrus) and olive baboons (Papio anubis) are active at night. MATERIALS AND METHODS: We deployed GPS collars with tri-axial accelerometer data loggers on 18 free-ranging adult females: 12 vervets spread among 5 social groups, and 6 olive baboons spread among 4 groups...
June 2, 2017: American Journal of Physical Anthropology
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