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Round pneumonia in children

Nicole Salazar-Austin, Alvaro A Ordonez, Alice Jenh Hsu, Jane E Benson, Mahadevappa Mahesh, Elizabeth Menachery, Jafar H Razeq, Max Salfinger, Jeffrey R Starke, Aaron M Milstone, Nicole Parrish, Eric L Nuermberger, Sanjay K Jain
Extensively drug-resistant (XDR) tuberculosis is becoming increasingly prevalent worldwide, but little is known about XDR tuberculosis in young children. In this Grand Round we describe a 2-year-old child from the USA who developed pneumonia after a 3 month visit to India. Symptoms resolved with empirical first-line tuberculosis treatment; however, a XDR strain of Mycobacterium tuberculosis grew in culture. In the absence of clinical or microbiological markers, low-radiation exposure pulmonary CT imaging was used to monitor treatment response, and guide an individualised drug regimen...
December 2015: Lancet Infectious Diseases
Jia Lu Cheng, Chun-Chih Peng, Nan-Chang Chiu, Li-Chuan Weng, Yu-Ying Chiu, Lung Chang, Daniel Tsung-Ning Huang, Fu-Yuan Huang, Chang-Pan Liu, Hsin Chi
BACKGROUND/PURPOSE: Respiratory infections caused by human adenoviruses (HAdV) are worldwide, and have significantly increased recently in Taiwan. This study aimed to clarify the molecular epidemiology and risk factors of HAdV severe infections and pneumonia among Taiwanese children. METHODS: Patients with HAdV infections and hospitalized in a medical center between 2009 and 2013 were divided into severe or nonsevere HAdV infections based on whether or not they received intensive care...
September 9, 2015: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
D N Tran, Q D Trinh, N T K Pham, T M H Pham, M T Ha, T Q N Nguyen, S Okitsu, H Shimizu, S Hayakawa, M Mizuguchi, H Ushijima
Molecular epidemiology and clinical impact of human rhinovirus (HRV) are not well documented in tropical regions. This study compared the clinical characteristics of HRV to other common viral infections and investigated the molecular epidemiology of HRV in hospitalized children with acute respiratory infections (ARIs) in Vietnam. From April 2010 to May 2011, 1082 nasopharyngeal swabs were screened for respiratory viruses by PCR. VP4/VP2 sequences of HRV were further characterized. HRV was the most commonly detected virus (30%), in which 70% were diagnosed as either pneumonia or bronchiolitis...
January 2016: Epidemiology and Infection
Israel Matías, Inés García, Lourdes García-Fragoso, Gilberto Puig, Lourdes Pedraza, Luis Rodríguez, Alvaro Santaella, Sylvia Arce, Marilyn Toledo, Edwin Soto, Marta Valcárcel
OBJECTIVE: The respiratory syncytial virus (RSV) is the most significant viral pathogen causing bronchiolitis and pneumonia in infants, today. In tropical climates the RSV infection may occur throughout the year. The purpose of this study was to asses RSV infections during the 2009‒2010 RSV season in children under 2 years of age and to evaluate the trend of positive RSV tests in the period of 2007 to 2009. METHODS: A retrospective review of data collected from 6 hospitals in Puerto Rico was performed...
June 2015: Puerto Rico Health Sciences Journal
Sarah E Burr, Sally Milne, James Jafali, Ebrima Bojang, Megha Rajasekhar, John Hart, Emma M Harding-Esch, Martin J Holland, David C W Mabey, Ansumana Sillah, Robin L Bailey, Anna Roca
OBJECTIVE: To evaluate the effect of repeated mass drug administration (MDA) of azithromycin in the Gambia on the nasopharyngeal carriage of Streptococcus pneumoniae and on the emergence of antibiotic-resistant strains. METHODS: This study involved villages that participated in a cluster randomized trial comparing the effect of one versus three azithromycin MDA rounds on the prevalence of trachoma. Only villages in which most children received 7-valent pneumococcal conjugate vaccine were included...
July 1, 2014: Bulletin of the World Health Organization
Yi Zhang, Yong-Sheng Yu, Zheng-Hao Tang, Xiao-Hua Chen, Guo-Qing Zang
Round pneumonia is an uncommon form of pulmonary infection usually found in children. It may resemble pulmonary neoplasm on radiographs. We present a case of round pneumonia in a 43-year-old male with a history of smoking and a family history of lung cancer. The patient was treated with antibiotics for more than two weeks, after which the infection resolved completely both clinically and radiologically. Clinicians should consider this uncommon type of pneumonia in the differential diagnosis of spherical pulmonary masses to avoid unnecessary diagnostic tests...
January 2014: Southeast Asian Journal of Tropical Medicine and Public Health
Jang-Mi Kwon, Jae Won Shim, Deok Soo Kim, Hye Lim Jung, Moon Soo Park, Jung Yeon Shim
PURPOSE: In this study, we aimed to investigate the prevalence of year-round respiratory viral infection in children with lower respiratory tract infection (LRTI) and the relationship between respiratory viral infection and allergen sensitization in exacerbating asthma. METHODS: We investigated the sources for acute LRTIs in children admitted to our hospital from May 2010 to April 2011. The 6 most common respiratory viruses were isolated from nasopharyngeal aspirate using multiplex reverse transcription-polymerase chain reaction in 309 children; respiratory syncytial virus (RSV), adenovirus (AV), parainfluenza virus (PIV), influenza virus (IFV), human metapneumovirus (hMPV), rhinovirus (RV)...
January 2014: Korean Journal of Pediatrics
Jie Ying Lee, Leon Tak Keet Lim, Seng Hock Quak, Krishnan Prabhakaran, Marion Aw
AIM: Cholangitis is a well-known complication that contributes to morbidity, mortality, as well as health-care utilisation in children with biliary atresia who have undergone the Kasai portoenterostomy. The aim of the study was to determine the common causative organisms for cholangitis and characterise its burden, health-care resource and service utilisation and cost. METHODS: This was a retrospective chart review of children who underwent Kasai portoenterostomy in our institution from 1988 to 2011...
March 2014: Journal of Paediatrics and Child Health
Dinh Nguyen Tran, Tran Quynh Nhu Nguyen, Tuan Anh Nguyen, Satoshi Hayakawa, Masashi Mizuguchi, Hiroshi Ushijima
Acute respiratory infections are the major cause of morbidity and mortality globally. Human bocavirus (HBoV), a novel virus, is recognized to increasingly associate with previously unknown etiology respiratory infections in young children. In this study, the epidemiological, clinical, and molecular characteristics of HBoV infections were described in hospitalized Vietnamese pediatric patients. From April 2010 to May 2011, 1,082 nasopharyngeal swab samples were obtained from patients with acute respiratory infections at the Children's Hospital 2, Ho Chi Minh City, Vietnam...
June 2014: Journal of Medical Virology
Ashley Meekin Johnson, Najmul Salman, Charles Gaymes, Andrew Rivard
SESSION TYPE: Critical Care Student/Resident Case Report Posters IPRESENTED ON: Tuesday, October 23, 2012 at 01:30 PM - 02:30 PMINTRODUCTION: Viral pericardial effusions, have not been reported to cause airway compression possibly as the fluid does not create a mass effect. In young children, external compression of the bronchi may be seen more frequently due to the softer cartilage of these airways. (1)CASE PRESENTATION: A 5-month-old white female with an insignificant past medical history was admitted to an outside hospital with a low- grade fever of 10 days, labored breathing, and decreased appetite and urinary output...
October 1, 2012: Chest
Venugopal Panicker, Raseela Karunakaran
SESSION TYPE: Airway Global Case Report PostersPRESENTED ON: Tuesday, October 23, 2012 at 01:30 PM - 02:30 PMINTRODUCTION: Even though mediastinal neurofibromas are common, intrapulmonary neurofibromas are rare. Nodular shadows in the chest x-rays of neurofibromatosis are often due to the lesions in the chest wall. In this paper, we present a case of intrathoracic neurofibroma with intrabronchial extension. Lesions extending into the bronchial lumen making bronchoscopic diagnosis possible, as in this case is extremely rare...
October 1, 2012: Chest
Imran Sağlık, Derya Mutlu, Gözde Ongüt, Sevtap Velipaşaoğlu Güney, Aykut Ozkul, Dilara Oğünç, Dilek Colak
Adenoviruses which are one of the causative agents of acute respiratory tract infections at all age groups worldwide, can lead to epidemic, endemic or sporadic infections year-round. Adenovirus infections in lower respiratory tract can be presented as bronchitis, bronchiolitis and pneumonia. The aim of this study was to investigate the presence of adenoviruses as the etiologic agent of lower respiratory tract infections (LRTIs) in children by cell culture, polymerase chain reaction (PCR) and direct fluorescence antibody (DFA) test...
April 2013: Mikrobiyoloji Bülteni
Edina Torgyekes, Alan L Shanske, Kwame Anyane-Yeboa, Odelia Nahum, Sara Pirzadeh, Einat Blumfield, Vaidehi Jobanputra, Dorothy Warburton, Brynn Levy
We report on two patients with overlapping small interstitial deletions involving regions 14q12 to 14q13.1. Both children had severe developmental delay, failure to thrive, microcephaly, and distinctive facial features, including abnormal spacing of the eyes, epicanthal folds, sloping forehead, low-set ears, rounded eyebrows with triangular media aspect and outer tapering, depressed and broad nasal bridge, small mouth, a long philtrum, and a prominent Cupid's bow. Brain MRI of both children showed partial agenesis of the corpus callosum...
August 2011: American Journal of Medical Genetics. Part A
Jannell A Plouffe
In 2004, the pediatric intensive unit at the Winnipeg Children's Hospital began a journey into space, engaging in the evolving culture of safety emerging in Canada. This process started with the joining of the Canadian ICU Collaborative on Patient Safety, where the first project focused on decreasing catheter-related blood stream infections (CRBSIs). This single project created the impetus for the mission: 2007 Solar system of safety. The solar system analogy was a powerful methodology to engage staff to travel to the different planets (projects) and step outside of their comfort zone into what some perceived as zero gravity...
2010: Dynamics: the Official Journal of the Canadian Association of Critical Care Nurses
Ricardo Restrepo, Rajaneeshankar Palani, Uma M Matapathi, Yen-Ying Wu
Various diseases in the pediatric age group can present as an intrathoracic rounded opacity on a chest radiograph. The purpose of this pictorial essay is to emphasize the imaging appearance of round pneumonia, an entity that occurs especially in the pediatric population. Additional pathologies with similar chest radiographic appearances are also presented. The diagnosis of round pneumonia should be made in children who have the typical clinical presentation along with chest radiographs demonstrating the characteristic findings...
December 2010: Pediatric Radiology
James Mark Simmerman, Malinee Chittaganpitch, Jens Levy, Somrak Chantra, Susan Maloney, Timothy Uyeki, Peera Areerat, Somsak Thamthitiwat, Sonja J Olsen, Alicia Fry, Kumnuan Ungchusak, Henry C Baggett, Supamit Chunsuttiwat
BACKGROUND: Data on the incidence, seasonality and mortality associated with influenza in subtropical low and middle income countries are limited. Prospective data from multiple years are needed to develop vaccine policy and treatment guidelines, and improve pandemic preparedness. METHODS: During January 2005 through December 2008, we used an active, population-based surveillance system to prospectively identify hospitalized pneumonia cases with influenza confirmed by reverse transcriptase-polymerase chain reaction or cell culture in 20 hospitals in two provinces in Thailand...
2009: PloS One
Andrew Fretzayas, Maria Moustaki, Efthimia Alexopoulou, Olga Liapi, Polyxeni Nicolaidou, Konstantinos N Priftis
BACKGROUND: Community-acquired pneumonia in children is rarely depicted as round opacity. The aim of the present study was therefore to describe the clinical and laboratory characteristics of round pneumonia in children. METHODS: The clinical series consisted of 30 children aged 1-7 years (mean age, 3.4 +/- 1.8 years) who were compared to an equal number of children with segmental or lobar pneumonia aged 3-11 years (mean age, 5.5 +/- 2.7 years). RESULTS: Round pneumonia was localized more often in the lower lobe (17/30), and the right side was more commonly affected (20/30)...
June 2010: Pediatrics International: Official Journal of the Japan Pediatric Society
Wei Ji, Yuqing Wang, Zhengrong Chen, Xuejun Shao, Zhenghua Ji, Jun Xu
This study was conducted to determine the seasonal distribution of human metapneumovirus (hMPV) infection in the Suzhou area of China, to discuss the epidemiological and clinical features of the disease, and to examine the genetic variation of the virus in China. From November 2005 to October 2006, a total of 1932 children with acute respiratory infections, admitted to the Children's Hospital Affiliated to Soochow University, were tested for the presence of hMPV using a reverse-transcription polymerase chain reaction...
2009: Scandinavian Journal of Infectious Diseases
Marc Tebruegge, Anastasia Pantazidou, Kent Thorburn, Andrew Riordan, Jonathan Round, Claudine De Munter, Sam Walters, Nigel Curtis
The published literature on bacterial tracheitis is limited. We report the first multi-centre study of bacterial tracheitis together with a concise review of the literature. We conducted a retrospective study of cases admitted during the period 1993-2007 to 3 tertiary paediatric centres in the United Kingdom and 1 in Australia. A total of 34 cases were identified. 31 patients (91%) required intubation. Complications included cardiorespiratory arrest in 1, ARDS in 1, hypotension in 10, toxic shock syndrome in 1 and renal failure in 1 patient(s)...
2009: Scandinavian Journal of Infectious Diseases
Ray Sandip Kumar, Mallik Sarmila, Mitra Shyama Prasad, Mehta Pankaj, Kumar Satish
The present study was carried out to find out the incidence of measles in under five children and its complications in four selected urban slums of inter-state border districts of West Bengal. 20 cluster sampling technique was followed and in each cluster 250 under five children were covered. Paramedical workers found out the children of the target age group who had the history of measles in past one year and Medical Officer confirmed the case following standard case definition. Incidence of measles was round to be 3...
March 2008: Journal of Communicable Diseases
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