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Round pneumonia

Koichi Sakakura, Masayuki Tazawa, Natsuko Otani, Masato Takagi, Mariko Morita, Minori Kurosaki, Tomoko Chiyoda, Yuri Kanai, Ayaka Endo, Takaaki Murata, Masato Shino, Yuki Yokobori, Kenji Shirakura, Naoki Wada, Kazuaki Chikamatsu
OBJECTIVES: The management of dysphagia requires a multidisciplinary approach, especially in large-scale hospitals. We introduce a novel protocol using a Wi-Fi-based flexible endoscopic evaluation of swallowing (FEES) system and aim to verify its effectiveness in evaluation and rehabilitation of inpatients with dysphagia. METHOD: We conducted novel Wi-Fi-based FEES at the bedside using 3 iPads as monitors and recorders. Functional outcomes of swallowing in 2 different hospitals for acute care with conventional wired or wireless FEES were compared retrospectively...
January 2017: Annals of Otology, Rhinology, and Laryngology
Benjamin Jarrett, Sehem Ghazala, Joseph Chao, Sachin Chaudhary
The mortality rate for Stevens-Johnson syndrome (SJS) is estimated to be ∼12% and for toxic epidermal necrolysis (TEN) it is around 30%. It continues to be a severe life-threatening drug reaction. We present a 60-year-old Caucasian man with a medical history significant for breast cancer status post mastectomy and chemotherapy with docetaxel and cyclophosphamide who presented with severe mucositis and a progressing skin rash consistent with SJS. He was started on high-dose corticosteroids and IVIG but continued to have worsening mucosal ulcerations and severe bleeding from the oral, conjunctival and genital mucosa...
November 15, 2016: BMJ Case Reports
Janko Vlaović, Gorazd Voga
A 72-year-old patient was admitted to the medical intensive care unit due to a right-sided, hospital-acquired pneumonia and septic shock with respiratory failure and deterioration of chronic renal failure. During hospitalization the patient required hemodynamic support with norepinephrine and dobutamine, mechanical ventilation and hemodialysis. The patient suffered a non-ST segment elevation myocardial infarction (NSTEMI) and received dual antiplatelet therapy. After 14 days an acute intrapulmonary infiltrate of unknown origin developed, accompanied by fever and a significant increase of the C‑reactive protein (CRP) level...
October 28, 2016: Wiener Klinische Wochenschrift
Santiago Sánchez Pardo, Javier Duque, Javier Enrique Fajardo
Glomus tumors are uncommon tumors that are originated from smooth muscle cells of the neuromioarterials glomus bodies located in the arteriovenous anastomoses subcutaneous tissue or deep dermis of the extremities, mainly in the palms of the hands, wrists and subungual areas of the fingers. Carcinoid tumor, as the glomus tumor, can show an organoid pattern, increased vascularity, and uniform, round cells with eosinophilic cytoplasm, but usually are positive for cytokeratin and always stained with chromogranin and synaptophysin showing negative for smooth muscle markers which is presented in our case...
2016: Respiratory Medicine Case Reports
Giorgia A Osman, Alberto Ricci, Fabrizio Terzo, Carlo Falasca, Maria R Giovagnoli, Pierdonato Bruno, Andrea Vecchione, Salvatore Raffa, Sabatino Valente, Maria R Torrisi, Chiara De Dominicis, Simonetta Giovagnoli, Salvatore Mariotta
INTRODUCTION: Lipoid pneumonia is a clinical condition that may be initially asymptomatic or confused with an infectious or malignant lung disease. OBJECTIVES: We report four cases of this pathological condition. METHODS: The first case concerned an 85-year old woman with bilateral confluent pulmonary opacities, ground-glass type. Diagnosis was based on the cytology of the bronchoalveolar lavage (BAL) fluid followed by its ultrastructural examination...
September 22, 2016: Clinical Respiratory Journal
Caio César Inaco Cirino, André Peluso Nogueira, André Amate Neto, Patricia Cristina Urbano, Tales Rubens de Nadai
BACKGROUND: We herein present a case in which a Toxoplasma cyst was found in a transbronchial biopsy specimen from an immunocompetent patient with negative serology for the parasite. CASE PRESENTATION: An 18-year-old Brazilian man presented with a 1-week history of dyspnea and fever and was diagnosed with right lower lobe pneumonia. He began inpatient treatment with intravenous antibiotics. During treatment, a bronchoscopy with bronchoalveolar lavage and transbronchial biopsy was performed...
2016: Journal of Medical Case Reports
Narin Sriratanaviriyakul, Hanh H La, Timothy E Albertson
BACKGROUND: Chronic eosinophilic pneumonia is a rare idiopathic interstitial lung disease. The nearly pathognomonic radiographic finding is the peripheral distribution of alveolar opacities. Pleural effusions are rarely seen. We report a case of chronic eosinophilic pneumonia with transudative eosinophilic pleural effusion. CASE PRESENTATION: A 57-year-old Hispanic woman, a nonsmoker with a history of controlled asthma, presented to the hospital with unresolving pneumonia despite three rounds of antibiotics over a 2-month period...
2016: Journal of Medical Case Reports
Esther Coker, Jenny Ploeg, Sharon Kaasalainen, Nancy Carter
AIM AND OBJECTIVE: The purpose of this study was to explore how nurses provide bedtime oral hygiene care, how they decide on interventions provided, and what factors influence their ability to provide oral care. BACKGROUND: Current evidence links poor oral hygiene to systemic and infectious diseases such as pneumonia. Hospitalised patients, who now retain their teeth into older adulthood, often rely on nurses to provide oral hygiene care. Nurses have the potential to impact oral health outcomes and quality of life by controlling plaque...
June 29, 2016: International Journal of Older People Nursing
Alexandre B Cavalcanti, Fernando Augusto Bozza, Flavia R Machado, Jorge I F Salluh, Valquiria Pelisser Campagnucci, Patricia Vendramim, Helio Penna Guimaraes, Karina Normilio-Silva, Lucas Petri Damiani, Edson Romano, Fernanda Carrara, Juliana Lubarino Diniz de Souza, Aline Reis Silva, Grazielle Viana Ramos, Cassiano Teixeira, Nilton Brandão da Silva, Chung-Chou H Chang, Derek C Angus, Otavio Berwanger
IMPORTANCE: The effectiveness of checklists, daily goal assessments, and clinician prompts as quality improvement interventions in intensive care units (ICUs) is uncertain. OBJECTIVE: To determine whether a multifaceted quality improvement intervention reduces the mortality of critically ill adults. DESIGN, SETTING, AND PARTICIPANTS: This study had 2 phases. Phase 1 was an observational study to assess baseline data on work climate, care processes, and clinical outcomes, conducted between August 2013 and March 2014 in 118 Brazilian ICUs...
April 12, 2016: JAMA: the Journal of the American Medical Association
Mate M Soric, Jason E Glowczewski, Rachael M Lerman
PURPOSE: Results of a study of economic and patient satisfaction outcomes of implementing a "layered learning model" (LLM) in a community hospital are presented. METHODS: An LLM consisting of a clinical pharmacist, two postgraduate year 1 pharmacy residents, and pharmacy students participating in rounds and providing patient education was implemented at a small community hospital. The primary endpoint was the difference in mean total drug cost per discharge in cases managed by physicians who rounded with pharmacy representatives (the intervention group) and cases managed by physicians who rounded with no pharmacist present (the control group)...
April 1, 2016: American Journal of Health-system Pharmacy: AJHP
Yukiyoshi Hyo, Tomoya Fujisaki, Rui Hyo, Hiroki Tanaka, Tamotsu Harada
Iliopsoas abscess was once an uncommon condition but now occurs somewhat more frequently due to the increasing number of immunocompromised patients, such as those with diabetes. We encountered a case of iliopsoas abscess following chemoradiotherapy for hypopharyngeal cancer. A 60-year-old man was admitted for a sore throat and left neck swelling. Hypopharyngeal cancer was diagnosed, but the patient refused surgery. After two rounds of chemotherapy, febrile neutropenia developed and chest computed tomography (CT) revealed an iliopsoas abscess...
2016: Case Reports in Otolaryngology
Barbara Simons, Marjolein van Waas, Jacintha T C M Verhallen
A 5-year-old boy presented with vomiting and dyspnoea. His chest X-ray showed two round consolidations in his right lung, one of them with air bronchograms, which were caused by round pneumonia. Round pneumonia presents with multiple lesions in only 2% of cases.
2016: Nederlands Tijdschrift Voor Geneeskunde
Wipa Reechaipichitkul, Pachara Thanasatirakul
Nocardia thyroid abscess with pneumonia is a rare clinical presentation. We reported a liver transplant recipient with Nocardia thyroiditis and pneumonia after receiving high dose immunosuppressants to preserve his graft. The patient is a 50-year-old male who developed hepatitis C virus-related liver cirrhosis and received a liver transplant. Seven months post-transplantation the patient developed graft rejection, which was treated with 3 days pulse dose methyl-prednisolone followed by an increased dose of his tracolimus, mycophenolate and prednisolone...
November 2015: Southeast Asian Journal of Tropical Medicine and Public Health
Paulina Aguilera, Andrés Marcoleta, Pablo Lobos-Ruiz, Rocío Arranz, José M Valpuesta, Octavio Monasterio, Rosalba Lagos
Microcin E492 (MccE492) is a pore-forming bacteriocin produced and exported by Klebsiella pneumoniae RYC492. Besides its antibacterial activity, excreted MccE492 can form amyloid fibrils in vivo as well as in vitro. It has been proposed that bacterial amyloids can be functional playing a biological role, and in the particular case of MccE492 it would control the antibacterial activity. MccE492 amyloid fibril's morphology and formation kinetics in vitro have been well-characterized, however, it is not known which amino acid residues determine its amyloidogenic propensity, nor if it forms intracellular amyloid inclusions as has been reported for other bacterial amyloids...
2016: Frontiers in Microbiology
D O'Toole, K S Sondgeroth
Histophilus somni is responsible for sporadic disease worldwide in cattle and, to a lesser extent, in small ruminants, bighorn sheep (Ovis canadensis), and North American bison (Bison bison). The importance of H. somni diseases can be attributed to improved clinical and laboratory recognition, combined with the growth in intensive management practices for cattle. Although outbreaks of bovine histophilosis can occur year-round, in northern and southern hemispheres, it is most frequent in late fall and early winter...
2016: Current Topics in Microbiology and Immunology
Yuichiro Okumura, Junji Kawada, Kazumasa Fujitani, Rie Nakatsuka, Masaaki Motoori, Syoichi Fukuda, Shigetoshi Shimamoto, Kazuhiro Nishikawa, Masatoshi Nomura, Susumu Miyazaki, Katsuki Danno, Masaru Kubota, Chu Matsuda, Kazuhiro Iwase, Yasuhiro Tanaka
We report the case of a 70-year-old man with unresectable advanced gastric cancer because of invasion to the pancreas and multiple liver metastases. He could have continued with fourth-line chemotherapy by controlling intermittent bleeding from the cancer by means of 2 rounds of radiotherapy and trans-arterial embolization. The serum hemoglobin level declined to 4.5 g/dL during second-line chemotherapy. As the venous bleeding from the cancer was difficult to control by endoscopic hemostasis, radiotherapy with 40 Gy/20 fractions was applied to the cancer...
November 2015: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Ferran Morell, Dirk Esser, Jonathan Lim, Susanne Stowasser, Alba Villacampa, Diana Nieves, Max Brosa
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a form of chronic fibrosing interstitial pneumonia characterized by progressive worsening of dyspnea and lung function, with a poor prognosis. The objective of this study was to determine treatment patterns, resource use and costs of managing Spanish patients with IPF. METHODS: A three-round Delphi consensus panel of 15 clinical experts was held between December 2012 and June 2013 using questionnaires to describe the management of patients with IPF...
January 12, 2016: BMC Pulmonary Medicine
Kelly Victor, Nicholas A Barrett, Stuart Gillon, Abigail Gowland, Christopher I S Meadows, Nicholas Ioannou
UNLABELLED: Extracorporeal membrane oxygenation (ECMO) is an advanced form of organ support indicated in selected cases of severe cardiovascular and respiratory failure. Echocardiography is an invaluable diagnostic and monitoring tool in all aspects of ECMO support. The unique nature of ECMO, and its distinct effects upon cardio-respiratory physiology, requires the echocardiographer to have a sound understanding of the technology and its interaction with the patient. In this article, we introduce the key concepts underpinning commonly used modes of ECMO and discuss the role of echocardiography...
June 1, 2015: Echo Research and Practice
Camille L A Hamula, Hanyong Peng, Zhixin Wang, Gregory J Tyrrell, Xing-Fang Li, X Chris Le
Streptococcus pyogenes is a clinically important pathogen consisting of various serotypes determined by different M proteins expressed on the cell surface. The M type is therefore a useful marker to monitor the spread of invasive S. pyogenes in a population. Serotyping and nucleic acid amplification/sequencing methods for the identification of M types are laborious, inconsistent, and usually confined to reference laboratories. The primary objective of this work is to develop a technique that enables generation of aptamers binding to specific M-types of S...
March 15, 2016: Methods: a Companion to Methods in Enzymology
R Andres Floto, Kenneth N Olivier, Lisa Saiman, Charles L Daley, Jean-Louis Herrmann, Jerry A Nick, Peadar G Noone, Diana Bilton, Paul Corris, Ronald L Gibson, Sarah E Hempstead, Karsten Koetz, Kathryn A Sabadosa, Isabelle Sermet-Gaudelus, Alan R Smyth, Jakko van Ingen, Richard J Wallace, Kevin L Winthrop, Bruce C Marshall, Charles S Haworth
Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms that can cause chronic pulmonary infection, particularly in individuals with pre-existing inflammatory lung disease such as cystic fibrosis (CF). Pulmonary disease caused by NTM has emerged as a major threat to the health of individuals with CF but remains difficult to diagnose and problematic to treat. In response to this challenge, the US Cystic Fibrosis Foundation (CFF) and the European Cystic Fibrosis Society (ECFS) convened an expert panel of specialists to develop consensus recommendations for the screening, investigation, diagnosis and management of NTM pulmonary disease in individuals with CF...
January 2016: Thorax
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