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Round pneumonia

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https://www.readbyqxmd.com/read/29845357/serological-diagnosis-of-mycoplasma-pneumoniae-infection-by-using-the-mimic-epitopes
#1
Wenyuan Shi, Lanhua Zhao, Shengtao Li, Guizhen Xu, Yanhua Zeng
Nowadays, there is lack of effective serological detection method for Mycoplasma pneumoniae (M. pneumoniae) infection in clinic. In this study, the mimic epitopes of M. pneumoniae were screened to evaluate the role in the serodiagnosis of M. pneumoniae infection. The M. pneumoniae-positive serum was used as the target for biopanning to phage display random 7-peptide library. The positive phage clones were selected and the DNA were sequenced and analyzed by BLAST. The representative phages were identified using dot immunoblotting and ELISA...
May 29, 2018: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/29800690/cochrane-acute-respiratory-infections-group-s-stakeholder-engagement-project-identified-systematic-review-priority-areas
#2
Anna Mae Scott, Justin Clark, Liz Dooley, Ann Jones, Mark Jones, Chris Del Mar
OBJECTIVE: Cochrane Acute Respiratory Infections (ARI) Group conducts systematic reviews of the evidence for treatment and prevention of ARIs. We report the results of a prioritisation project, aiming to identify highest priority systematic review topics. STUDY DESIGN/SETTING: The project consisted of 2 Phases. Phase 1 analysed the gap between existing RCTs and Cochrane Systematic Reviews (reported previously). Phase 2 (reported here) consisted of a two-round survey...
May 22, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29735758/the-impact-of-active-metabolism-on-chlamydia-trachomatis-elementary-body-transcript-profile-and-infectivity
#3
Scott Grieshaber, Nicole Grieshaber, Hong Yang, Briana Baxter, Ted Hackstadt, Anders Omsland
Bacteria of the genus Chlamydia include the significant human pathogens C. trachomatis and C. pneumoniae All Chlamydiae are obligate intracellular parasites that depend on infection of a host cell and transition through a biphasic developmental cycle. Following host cell invasion by the infectious Elementary Body (EB), the pathogen transitions to the replicative but non-infectious Reticulate Body (RB). Differentiation of the RB back to the EB is essential to generate infectious progeny. While the EB form has historically been regarded as metabolically inert, maintenance of infectivity during incubation with specific nutrients has revealed active maintenance of the infectious phenotype...
May 7, 2018: Journal of Bacteriology
https://www.readbyqxmd.com/read/29720004/pulmonary-adenocarcinoma-mimicking-desquamative-interstitial-pneumonia-report-of-2-cases-with-genetic-analysis
#4
Masashi Miyaoka, Kazuhito Hatanaka, Masayuki Iwazaki, Naoya Nakamura
We report 2 cases of pulmonary adenocarcinoma mimicking desquamative interstitial pneumonia (DIP) with genetic analysis occurring in a 74-year-old woman and a 76-year-old woman. In both cases, the tumor was mainly composed of discohesive tumor cells, which filled and floated in the alveolar space in a DIP-like pattern. The tumor cells had abnormally large round to oval nuclei with fine chromatin and relatively abundant eosinophilic cytoplasm lacking pigmentation. Immunohistochemically, tumor cells in both cases were positive for CK7, TTF-1, napsin A, E-cadherin, β-catenin, and PD-L1 (one case had high expression and the other had low expression), and negative for CK5/6, CK20, p40, and ALK...
May 1, 2018: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29719793/an-unusual-case-of-lung-abscess-secondary-to-round-pneumonia-caused-by-recurrent-klebsiella-pneumoniae-strain-and-the-role-of-occult-metastases-tumor
#5
Shuchang An, Xiangli Li, Shenhai Wei, Chaofeng Luo, Rong Cui
Round pneumonia is an uncommon form of community-acquired pneumonia usually found in children. To this date, there has been no report on local pulmonary complications in this entity in adult patients. The present study reports a case of a 77-year-old male with lung abscess secondary to round pneumonia caused by recurrent Klebsiella pneumoniae infection accompanied by occult metastases tumor. Occult metastases may have played an important role in leading to cavity as in this present case. Further investigation regarding the relationship between recurrent infection and metastases is needed...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29710234/association-of-postoperative-readmissions-with-surgical-quality-using-a-delphi-consensus-process-to-identify-relevant-diagnosis-codes
#6
Hillary J Mull, Laura A Graham, Melanie S Morris, Amy K Rosen, Joshua S Richman, Jeffery Whittle, Edith Burns, Todd H Wagner, Laurel A Copeland, Tyler Wahl, Caroline Jones, Robert H Hollis, Kamal M F Itani, Mary T Hawn
Importance: Postoperative readmission data are used to measure hospital performance, yet the extent to which these readmissions reflect surgical quality is unknown. Objective: To establish expert consensus on whether reasons for postoperative readmission are associated with the quality of surgery in the index admission. Design, Setting, and Participants: In a modified Delphi process, a panel of 14 experts in medical and surgical readmissions comprising physicians and nonphysicians from Veterans Affairs (VA) and private-sector institutions reviewed 30-day postoperative readmissions from fiscal years 2008 through 2014 associated with inpatient surgical procedures performed at a VA medical center between October 1, 2007, and September 30, 2014...
April 18, 2018: JAMA Surgery
https://www.readbyqxmd.com/read/29666967/health-maintenance-in-inflammatory-bowel-disease
#7
REVIEW
Fazia A Mir, Sunanda V Kane
PURPOSE OF REVIEW: Patients with inflammatory bowel disease (IBD) are not receiving preventative care services at the same rate as the general population. IBD patients are at increased risk for infections, osteoporosis, and certain malignancies secondary to their disease and as they are on immunosuppressive therapy. They are a younger population and often times consider their gastroenterologist as their primary care physician. In this review, we discuss up-to-date evidence pertaining to vaccine-preventable illnesses in the immunosuppressed IBD patient, screening for bone health, cervical cancer, skin malignancies, psychological wellbeing, and smoking cessation...
April 17, 2018: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29650059/labyrinthitis-ossificans-in-a-cynomolgus-macaque-macaca-fascicularis
#8
Gayathriy Balamayooran, Hannah M Atkins, Christopher T Whitlow, Samuel T Aycock, Michael A Nader, J Mark Cline, David L Caudell
Labyrinthitis is inflammation of the membranous and bony labyrinth of the inner ear. Typical portals of entry includehematogenous spread from the cochlear vasculature, passage of otitis media pathogens through the round window, and mostcommonly, meningogenic spread from the subarachnoid space. The sequela of chronic inner ear inflammation is labyrinthitisossificans, in which inner ear structures are replaced by fibrous and osseous tissues. Labyrinthitis in humans has been reportedconcurrently with infection due to various viruses (for example, varicella-zoster, measles, mumps) and bacteria (for example,Treponema pallidum, Streptococcus pneumoniae) and may be associated with vertebrobasilar ischemia and meningitis...
April 12, 2018: Comparative Medicine
https://www.readbyqxmd.com/read/29605237/development-validation-and-application-of-a-ventilator-associated-pneumonia-prevention-checklist-in-a-single-cardiac-surgery-centre
#9
Luolan Li, Qing Wang, Jingjing Wang, Kai Liu, Pei Wang, Xian Li, Jing Yang, Jing Lu, Dian Li, Li Wang, Zhinong Wang, Fei Peng
OBJECTIVES: The purpose of this study was to develop, validate and apply a ventilator-associated pneumonia prevention checklist in a single cardiac surgery centre. METHODS: An initial checklist was designed based on the published care bundles for prevention of VAP and the Delphi method used for validation. A total of 20 experts were invited to score the items and give suggestions for the checklist. The final checklist was then applied to patients receiving cardiac surgery...
March 28, 2018: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/29604970/central-nervous-system-infection-with-toxoplasma-gondii
#10
Christina M Marra
Central nervous system infection by Toxoplasma gondii, or Toxoplasma encephalitis, is the most common cause of brain mass lesions in human immunodeficiency virus (HIV)-infected patients. It usually presents as one or more brain abscesses, but it can also cause a diffuse encephalitis or ventriculitis. Individuals who are Toxoplasma immunoglobulin G-seropositive, who have peripheral blood CD4+ T-cell concentrations below 200/μL, are not on antiretroviral therapy, and are not taking trimethoprim-sulfamethoxazole to prevent Pneumocystis pneumonia, are at particular risk for Toxoplasma encephalitis...
2018: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/29570586/hospitalization-rate-and-population-based-incidence-of-hospitalization-for-community-acquired-pneumonia-among-children-in-suzhou-china
#11
Wei Shan, Ting Shi, Xiyan Zhang, Jian Xue, Yin Wang, Jia Yu, Yukai Huang, Sheng Lin, Genming Zhao, Jianmei Tian, Tao Zhang
BACKGROUND: Data on hospitalization burden of CAP in children is very limited in China. This study aimed to estimate the hospitalization rate and population-based incidence of hospitalization of CAP for children <15 years of age in Suzhou, China. METHODS: This was a retrospective study of children hospitalized in Soochow University Affiliated Children's Hospital (SCH) from January 2010 to December 2014. Children who were residents of downtown Suzhou, 29 days to <15 years of age, with discharge diagnosis codes (ICD-10) including J09 to J18 and J20 to J22 were included...
March 22, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29475453/whole-transcriptome-analysis-reveals-differential-gene-expression-profile-reflecting-macrophage-polarization-in-response-to-influenza-a-h5n1-virus-infection
#12
Na Zhang, Yun-Juan Bao, Amy Hin-Yan Tong, Scott Zuyderduyn, Gary D Bader, J S Malik Peiris, Si Lok, Suki Man-Yan Lee
BACKGROUND: Avian influenza A H5N1 virus can cause lethal disease in humans. The virus can trigger severe pneumonia and lead to acute respiratory distress syndrome. Data from clinical, in vitro and in vivo suggest that virus-induced cytokine dysregulation could be a contributory factor to the pathogenesis of human H5N1 disease. However, the precise mechanism of H5N1 infection eliciting the unique host response are still not well understood. METHODS: To obtain a better understanding of the molecular events at the earliest time points, we used RNA-Seq to quantify and compare the host mRNA and miRNA transcriptomes induced by the highly pathogenic influenza A H5N1 (A/Vietnam/3212/04) or low virulent H1N1 (A/Hong Kong/54/98) viruses in human monocyte-derived macrophages at 1-, 3-, and 6-h post infection...
February 23, 2018: BMC Medical Genomics
https://www.readbyqxmd.com/read/29455182/pulmonary-inflammatory-myofibroblastic-tumour-misdiagnosed-as-a-round-pneumonia
#13
Samira Naime, Anjum Bandarkar, Gustavo Nino, Geovanny Perez
No abstract text is available yet for this article.
February 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29426802/development-of-mycoplasma-pneumoniae-biofilms-in-vitro-and-the-limited-role-of-motility
#14
Monica Feng, Andrew C Schaff, Sara A Cuadra Aruguete, Hailey E Riggs, Steven L Distelhorst, Mitchell F Balish
Mycoplasma pneumoniae is a bacterial pathogen of humans that is a major causative agent of chronic respiratory disease. M. pneumoniae infections often recur even after successful treatment of symptoms with antibiotics, and resistance to antibiotics is increasing worldwide, with nearly complete resistance in some places. Although biofilms often contribute to chronicity and resistance, M. pneumoniae biofilms remain poorly characterized. Scanning electron microscopy revealed that cells of wild-type (WT) M. pneumoniae strain M129 biofilms, as well as mutants II-3 and II-3R, in vitro became increasingly rounded as the biofilm towers matured over 5 days...
April 2018: International Journal of Medical Microbiology: IJMM
https://www.readbyqxmd.com/read/29424432/human-metapneumovirus-in-hospitalized-children-less-than-5-years-of-age-in-pakistan
#15
Mohammad T Yousafzai, Romesa Ibrahim, Rozina Thobani, Fatima Aziz, Asad Ali
Acute respiratory infection (ARI) is the second leading cause of death in children less than 5 years of age worldwide. Human Metapneumovirus (hMPV) is associated with around 5-7% of the total pneumonia admissions in children. The aim of this study was to determine the magnitude of hMPV associated hospitalizations among children, in Karachi, Pakistan. A 3 years prospective study was conducted at the Aga Khan University Hospital (AKUH), from August 2009 to June 2012. Children less than 5 years of age, admitted with ARIs, were enrolled...
June 2018: Journal of Medical Virology
https://www.readbyqxmd.com/read/29394837/-a-case-of-resection-of-obstructive-colon-cancer-associated-with-aspiration-pneumonia-under-combined-epidural-spinal-anesthesia
#16
Kazuki Hayashi, Kohei Murata, Atsushi Naito, Yoshinori Kagawa, Kenji Kawai, Ryota Mori, Yohei Nose, Yasuki Akiyama, Takuya Sakamoto, Kohei Murakami, Tohru Masuzawa, Yoshiteru Katsura, Yoshiaki Ohmura, Atsushi Takeno, Yutaka Takeda
An 89-year-old woman was admitted to our hospital with vomiting, abdominal distension, and anorexia.A CT scan revealed an enhanced thickening lesion on the wall of the ascending colon, and intestinal expansion from the small intestine to the caecum.On colon fibroscopy, a round tumor was observed adjacent to the oral side of the hepatic flexure even though the end of the microscope could not progress toward the deeper regions.As the obstructive colon cancer was complicated by the presence of aspiration pneumonia, surgery could not be performed under general anesthesia...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29390500/development-of-indicators-for-assessing-rational-drug-use-to-treat-community-acquired-pneumonia-in-children-in-hospitals-and-clinics-a-modified-delphi-study
#17
Wenrui Li, Linan Zeng, Jialian Li, Liang Huang, Ge Gui, Jie Song, Lina Chen, Lucan Jiang, Lingli Zhang
Community-acquired pneumonia (CAP) is a common infectious disease in children. Rational drug use (RDU) is an important approach to reducing the disease burden and mortality rate of CAP in children. There are no monitoring indicators for assessing RDU in children. This study aimed to develop a set of indicators to assess RDU to treat CAP in children in hospitals and clinics using a modified Delphi method.Initial indicators were generated based on a systematic review of guidelines and studies investigating CAP in children...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29341168/in-search-of-a-counter-you-can-count-on-relative-efficacy-of-human-visual-and-automated-colony-counting
#18
L M Young, D J Rieman, L Walden, V A Motz
To evaluate comparative efficiency of traditional vs automated colony counting methods, cultures of Escherichia coli (ATCC 25945), Staphylococcus epidermidis (ATCC 12225), Streptococcus pyogenes (ATCC19615) and Streptococcus pneumoniae (ATCC49619) were prepared as pure cultures and mixed cultures at 0·5 McFarland standard and serial dilutions were performed. Plates were inoculated in triplicate with 50, 125, 250 and 500 colony forming units and counted by four researchers, visually and using each of the automated counters...
March 2018: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/29330835/international-guidelines-for-groin-hernia-management
#19
(no author information available yet)
INTRODUCTION: Worldwide, more than 20 million patients undergo groin hernia repair annually. The many different approaches, treatment indications and a significant array of techniques for groin hernia repair warrant guidelines to standardize care, minimize complications, and improve results. The main goal of these guidelines is to improve patient outcomes, specifically to decrease recurrence rates and reduce chronic pain, the most frequent problems following groin hernia repair. They have been endorsed by all five continental hernia societies, the International Endo Hernia Society and the European Association for Endoscopic Surgery...
February 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29038446/external-quality-assurance-for-laboratory-identification-and-capsular-typing-of-streptococcus-pneumoniae
#20
Hans-Christian Slotved, Carmen L Sheppard, Tine Dalby, Arie van der Ende, Norman K Fry, Eva Morfeldt, Outi Nyholm, Assaf Rokney, Merav Ron, Lotta Siira, Kevin J Scott, Andrew Smith, Louise Thom, Maija Toropainen, Didrik F Vestrheim
An external quality assessment (EQA) scheme for pneumococcal serotype identification has been performed over a period of 11 years, by a network of European pneumococcal reference laboratories. We report the results from the EQA, and present an assessment of the acceptability and utility of the EQA scheme. Reports from 22 EQA panels distributed in 2005-2016 were analysed. Each EQA panel consisted of seven isolates. A questionnaire including seven questions related to the acceptability and utility of the EQA scheme was distributed to all participating laboratories...
October 16, 2017: Scientific Reports
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