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Ultrasound AND psoriatic arthritis

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https://www.readbyqxmd.com/read/28277255/recommendations-for-the-use-of-ultrasound-and-magnetic-resonance-in-patients-with-spondyloarthritis-including-psoriatic-arthritis-and-patients-with-juvenile-idiopathic-arthritis
#1
Jacqueline Uson, Estibaliz Loza, Ingrid Möller, Carlos Acebes, Jose Luis Andreu, Enrique Batlle, Ángel Bueno, Paz Collado, Juan Manuel Fernández-Gallardo, Carlos González, Mercedes Jiménez Palop, María Pilar Lisbona, Pilar Macarrón, Joan Maymó, Jose Antonio Narváez, Victoria Navarro-Compán, Jesús Sanz, M Piedad Rosario, Esther Vicente, Esperanza Naredo
OBJECTIVE: To develop evidence-based recommendations on the use of ultrasound (US) and magnetic resonance imaging in patients with spondyloarthritis, including psoriatic arthritis, and juvenile idiopathic arthritis. METHODS: Recommendations were generated following a nominal group technique. A panel of experts (15 rheumatologists and 3 radiologists) was established in the first panel meeting to define the scope and purpose of the consensus document, as well as chapters, potential recommendations and systematic literature reviews (we used and updated those from previous EULAR documents)...
October 27, 2016: Reumatología Clinica
https://www.readbyqxmd.com/read/28181179/clinical-examination-ultrasound-and-mri-imaging-of-the-painful-elbow-in-psoriatic-arthritis-and-rheumatoid-arthritis-which-is-better-ultrasound-or-mr-for-imaging-enthesitis
#2
Clare Groves, Muthusamy Chandramohan, Ne Siang Chew, Tariq Aslam, Philip S Helliwell
INTRODUCTION: The purpose of the current study was to examine the painful elbow, and in particular enthesitis, in psoriatic arthritis (PsA) and rheumatoid arthritis (RA) using clinical examination, ultrasonography (US) and magnetic resonance imaging (MRI). METHODS: Patients with elbow pain (11 with PsA and 9 with RA) were recruited. Clinical examination, US and MRI studies were performed on the same day. For enthesitis, the common extensor and flexor insertions and the triceps insertion were imaged (20 patients, giving a total of 60 sites with comparative data)...
February 8, 2017: Rheumatology and Therapy
https://www.readbyqxmd.com/read/28119289/synovial-features-of-patients-with-rheumatoid-arthritis-and-psoriatic-arthritis-in-clinical-and-ultrasound-remission-differ-under-anti-tnf-therapy-a-clue-to-interpret-different-chances-of-relapse-after-clinical-remission
#3
Stefano Alivernini, Barbara Tolusso, Luca Petricca, Laura Bui, Gabriele Di Sante, Giusy Peluso, Roberta Benvenuto, Anna Laura Fedele, Franco Federico, Gianfranco Ferraccioli, Elisa Gremese
OBJECTIVE: To define the synovial characteristics of patients with rheumatoid arthritis (RA) and psoriatic arthritis (PsA) in clinical and ultrasound remission achieved by combination therapy with methotrexate (MTX) and tumour necrosis factor (TNF) blockers. METHODS: Patients with RA in remission (n=25) (disease activity score (DAS)<1.6 for at least 6 months), patients with RA in low disease activity (LDA) (n=10) (1.6<DAS<2.4 for at least 6 months) and patients with PsA in remission (n=18) (DAS<1...
January 24, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28109577/traditional-cardiovascular-risk-factors-or-inflammation-which-factors-accelerate-atherosclerosis-in-arthritis-patients
#4
A Dalbeni, A Giollo, A Tagetti, S Atanasio, G Orsolini, G Cioffi, F Ognibeni, M Rossini, P Minuz, C Fava, O Viapiana
Patients with chronic inflammatory arthritis experience an increased incidence of cardiovascular (CV) events. In addition to visualizing atherosclerotic plaques, ultrasound examinations (USs) of the carotid arteries permit the measurement of subclinical markers of atherosclerosis, such as intima-media thickness (cIMT) and carotid segmental distensibility (cDC). The aims of the study were to identify the determinants of atherosclerosis acceleration (plaques, cIMT and cDC) in a sample of patients suffering from chronic arthritis and to compare these patients with a control group of people with ≤1 traditional risk factor (TRF) for CV disease...
January 14, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28089501/effectiveness-of-conventional-disease-modifying-antirheumatic-drugs-in-psoriatic-arthritis-a-systematic-review
#5
Jesús Maese, Petra Díaz Del Campo, Daniel Seoane-Mato, Mercedes Guerra, Juan D Cañete
BACKGROUND: Due to the clinical heterogeneity of psoriatic arthritis (PsA), recommendations have been developed by international groups to guide therapeutic decisions of the rheumatologist. The objective of the current systematic review (RS) was to evaluate the evidence of efficacy of disease-modifying antirheumatic drugs (DMARDs) in PsA. METHODS: Literature search in Medline, EMBASE, Cochrane Library, from 2008 to 2014. We included RS, randomized clinical trials and observational studies, in patients with PsA and an evaluation of efficiency of conventional DMARDs (methotrexate, sulfasalazine, leflunomide), according to the following outcomes: peripheral and axial symptoms; peripheral radiological damage; enthesitis according to power Doppler ultrasound or magnetic resonance imaging (enthesitis count before and after therapy); dactylitis; uveitis...
January 13, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/27995384/quantitative-imaging-by-pixel-based-contrast-enhanced-ultrasound-reveals-a-linear-relationship-between-synovial-vascular-perfusion-and-the-recruitment-of-pathogenic-il-17a-f-il-23-cd161-cd4-t-helper-cells-in-psoriatic-arthritis-joints
#6
Ugo Fiocco, Roberto Stramare, Veronica Martini, Alessandro Coran, Francesco Caso, Luisa Costa, Mara Felicetti, Gaia Rizzo, Matteo Tonietto, Anna Scanu, Francesca Oliviero, Bernd Raffeiner, Maristella Vezzù, Francesca Lunardi, Raffaele Scarpa, David Sacerdoti, Leopoldo Rubaltelli, Leonardo Punzi, Andrea Doria, Enrico Grisan
To develop quantitative imaging biomarkers of synovial tissue perfusion by pixel-based contrast-enhanced ultrasound (CEUS), we studied the relationship between CEUS synovial vascular perfusion and the frequencies of pathogenic T helper (Th)-17 cells in psoriatic arthritis (PsA) joints. Eight consecutive patients with PsA were enrolled in this study. Gray scale CEUS evaluation was performed on the same joint immediately after joint aspiration, by automatic assessment perfusion data, using a new quantification approach of pixel-based analysis and the gamma-variate model...
February 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/27932277/detection-of-subclinical-ultrasound-enthesopathy-and-nail-disease-in-patients-at-risk-of-psoriatic-arthritis
#7
Marie Acquitter, Laurent Misery, Alain Saraux, Luc Bressollette, Sandrine Jousse-Joulin
OBJECTIVES: To detect subclinical entheses and nail abnormalities using gray-scale (GS) and power Doppler ultrasonography (PDUS) between patients with nail psoriasis and those with inverse and scalp psoriasis. METHODS: In this prospective monocentric study, patients with nail, inverse and scalp psoriasis, without psoriatic arthritis or systemic treatment, were included. Clinical evaluation and ultrasonographic assessment of 14 entheses and 12 nails were done by a dermatologist (clinical assessment) and a rheumatologist (ultrasonographic assessment)...
December 5, 2016: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/27928500/recent-advances-in-understanding-and-managing-psoriatic-arthritis
#8
REVIEW
Dafna D Gladman
This article reviews recent advances in psoriatic arthritis (PsA) over the past several years with emphasis on early diagnosis, better understanding of pathogenesis, and new therapeutic approaches. Early diagnosis is important, since people who present late do not fare as well. There are a number of clinical, laboratory, and ultrasound features that can help identify patients destined to develop PsA, and several screening tools have been developed. It is recognized that genetic and epigenetic factors, as well as T cells and cytokines, play a role in the pathogenesis of PsA, and several targets have been identified for therapeutic interventions...
2016: F1000Research
https://www.readbyqxmd.com/read/27900348/implementation-of-musculoskeletal-ultrasonography-in-detection-of-early-juvenile-idiopathic-arthritis
#9
Ayman F Darwish, Faten M Ismael, Abdou Ell-Laban, Ahmed Hamed, Moustafa Abdel Kader, Ashraf Osman
AIM: To determine whether early clinical, laboratory and musculoskeletal ultrasound (MSUS) characteristics can be used as early detectors of juvenile idiopathic arthritis. PATIENTS AND METHODS: Forty (40) patients with juvenile idiopathic arthritis (JIA) diagnosed according to the ILAR criteria [1] and 20 healthy control children. All patients were subjected to the following assessment at base line and at follow up after 6 months: Clinical evaluation, MSUS examination and laboratory evaluation...
2016: European Journal of Radiology Open
https://www.readbyqxmd.com/read/27900299/assessment-of-enthesitis-in-patients-with-psoriatic-arthritis-using-clinical-examination-and-ultrasound
#10
Salome Kristensen, Jeppe Hagstrup Christensen, Erik Berg Schmidt, Jens Lykkegaard Olesen, Martin Berg Johansen, Kristian Bakke Arvesen, Annette Schlemmer
BACKGROUND: Enthesitis is a major feature of psoriatic arthritis. However, clinical assessment of enthesitis is known to lack accuracy and have poor interobserver reliability. OBJECTIVE: To determine effect of training on clinical assessment of enthesitis and to compare ultrasonography with clinical examination for the detection of entheseal abnormalities. METHODS: 20 rheumatologists performed repeated assessment of enthesitis in patients with established psoriatic arthritis before and after a 2-hour training session in standardised enthesitis count according to Leeds Enthesitis Index (LEI) and Spondyloarthritis Research Consortium of Canada Enthesitis Index (SPARCC)...
April 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27885882/state-of-the-art-of-ultrasound-in-the-assessment-of-psoriasis-and-psoriatic-arthritis
#11
Marwin Gutierrez, Gurjit S Kaeley, Chiara Bertolazzi, Carlos Pineda
Ultrasound (US) is a rapidly evolving technique that is gaining increasing success in the assessment of psoriatic arthritis (PsA). Recently, new research avenues have been opened, and these are focused on the potential of US for the assessment of extra musculoskeletal areas such as skin and nails. This permits work on the concept of 'holistic US assessment of PsA'. Areas covered: Here, we analyze the potential role of US in the global assessment of PsA. Additionally, we provide the current evidence supporting its application in routine clinical practice...
December 2, 2016: Expert Review of Clinical Immunology
https://www.readbyqxmd.com/read/27885376/high-prevalence-of-subclinical-atherosclerosis-in-psoriatic-arthritis-patients-a-study-based-on-carotid-ultrasound
#12
Rosario Ibáñez-Bosch, Juliana Restrepo-Velez, Miguel Medina-Malone, Laura Garrido-Courel, Inmaculada Paniagua-Zudaire, Eduardo Loza-Cortina
Analyse the presence of subclinical atherosclerosis in psoriatic arthritis patients (PsA). A cross-sectional study of 53 patients with PsA and 53 controls matched for age and sex was designed. Carotid intima-media thickness (IMT) and the presence of carotid plaques (CP) were assessed with carotid ultrasound. Data on cardiovascular (CV) risk factors were collected. Patients with PsA had a higher prevalence rate of obesity and tobacco smoking. CP were detected more frequently in patients with PsA than in controls with an OR of 4...
January 2017: Rheumatology International
https://www.readbyqxmd.com/read/27860304/nail-involvement-can-predict-enthesopathy-in-patients-with-psoriasis
#13
Maria Castellanos-González, Beatriz Esther Joven, Julio Sánchez, Eva María Andrés-Esteban, Francisco Vanaclocha-Sebastián, Pablo Ortiz Romero, Raquel Rivera Díaz
BACKGROUND: Although subclinical enthesopathy is a well-established diagnostic criterion for psoriatic arthritis (PsA), it is frequently overlooked, as many patients are asymptomatic. The possibility of finding a clinical clue predicting enthesopathy would help clinicians establish an early diagnosis of PsA. MATERIAL AND METHODS: A prospective single-center study of a total of 90 patients with psoriasis was conducted to assess the presence of entheseal abnormalities as detected by ultrasound, and to determine any correlation with nail involvement...
November 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/27749227/differing-local-and-systemic-inflammatory-burden-in-polyarticular-psoriatic-arthritis-and-rheumatoid-arthritis-patients-on-anti-tnf-treatment-in-clinical-remission
#14
Julio Ramírez, José Iniciarte-Mundo, Andrea Cuervo, Virginia Ruiz-Esquide, M Victoria Hernández, Raimón Sanmartí, Juan D Cañete
OBJECTIVES: To analyse clinical, serological and sonographic differences between rheumatoid arthritis (RA) and polyarticular psoriatic arthritis (PsA) patients on anti-TNF therapy in clinical remission. METHODS: Angiogenic and proinflammatory cytokine serum levels were determined by multiplex ELISA in patients with RA and PsA in clinical remission (DAS28-ESR<2.6), clinically-active RA patients (DAS28>3.2) and healthy controls. Ultrasound (US) scans were made of both wrists and hands...
October 7, 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27600991/an-ultrasonographic-study-of-enthesis-in-early-psoriatic-arthritis-patients-naive-to-traditional-and-biologic-dmards-treatment
#15
Fabio Massimo Perrotta, Davide Astorri, Marcello Zappia, Alfonso Reginelli, Luca Brunese, Ennio Lubrano
The aim of this study was to evaluate the rate of power Doppler ultrasound (PDUS) abnormalities at entheseal sites in patients with early psoriatic arthritis (PsA) naïve to traditional and biologic DMARDs and to compare the PDUS findings with clinical examination. PsA patients with early disease and naïve to traditional and biologic DMARDs were consecutively enrolled in this study. Patients underwent PDUS examination of the following bilateral entheseal sites: common extensor tendon at its insertion at the lateral humeral epicondyle; quadriceps tendon at its insertion at the superior pole of the patella; patellar tendon at its insertion at the tibial tuberosity; medial collateral ligament at its proximal insertion and Achilles tendon at its insertion at the calcaneus...
November 2016: Rheumatology International
https://www.readbyqxmd.com/read/27585683/the-association-of-hla-class-i-genes-and-the-extent-of-atherosclerotic-plaques-in-patients-with-psoriatic-disease
#16
Lihi Eder, Fatima Abji, Cheryl F Rosen, Vinod Chandran, Richard J Cook, Dafna D Gladman
OBJECTIVE: To investigate the association between HLA susceptibility and disease severity markers and the extent of atherosclerosis in patients with psoriatic disease. METHODS: White patients with psoriatic arthritis (PsA) and psoriasis without PsA (PsC) were recruited. An ultrasound of the carotid arteries was performed and the size of each atherosclerotic plaque was measured. The resulting score, the total plaque area (TPA), represented the extent of atherosclerosis...
October 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27576331/how-is-the-ultrasound-in-rheumatology-used-implemented-and-applied-in-latin-american-centers-results-from-a-multicenter-study
#17
Marwin Gutierrez, Cristina Hernandez-Diaz, Lucio Ventura-Rios, Lina María Saldarriaga-Rivera, Santiago Ruta, Magaly Alva, Claudia Mora -Trujillo, Wilkerson Pérez, Henry Terrazas, Rodolfo Del Carmen Arape Toyo, Maritza Quintero, Carla Solano, Oscar Sedano Santiago, Janet Grisel Huamán Sotomayor, Cesar Cefferino, Guillermo E Py, Marcelo J Audisio, Walter Javier Spindler, Horacio Berman, Carla Airoldi, Rómulo Wong, Ana Laura Álvarez Del Castillo Araujo, Mario E Díaz, Carmen Cerón Villaquiran, Rubén Darío Mantilla, José Alexandre Mendonça, Inês Guimarães da Silveira, Aline Defaveri do Prado, Melissa Cláudia Bisi, Violeta Rosario, Jeannette Medrano-Sánchez, Roberto Muñoz-Louis, Ana Cecilia Lozada-Navarro, Araceli Bernal, Maribel Lozano, Carlos Pineda
This study aimed to perform an overview of how ultrasound (US) is being used, implemented, and applied in rheumatologic centers in Latin America (LA). A retrospective, multicenter 1-year experience study was undertaken. Eighteen centers from eight countries were involved. The following information were collected: demographic data, indication to perform an US examination, physician that required the examination, and the anatomical region required for the examination. A total of 7167 patients underwent an US examination...
December 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27554830/carotid-plaque-and-bone-density-and-microarchitecture-in-psoriatic-arthritis-the-correlation-with-soluble-st2
#18
Jiayun Shen, Qing Shang, Chun-Kwok Wong, Edmund K Li, Emily W Kun, Isaac T Cheng, Martin Li, Tena K Li, Tracy Y Zhu, Cheuk-Man Yu, Ling Qin, Lai-Shan Tam
Psoriatic arthritis (PsA) patients have increased risk of both atherosclerosis and osteoporosis. Previous studies revealed that IL-33/ST2 axis may be related to both conditions; however, these associations were never evaluated in a single patients' group. Here we explored the association among plasma levels of IL-33 and its decoy receptor soluble ST2 (sST2), carotid plaque determined by ultrasound, and volumetric bone mineral density (vBMD)/microstructure of distal radius measured by high-resolution peripheral quantitative computed tomography (HR-pQCT) in 80 PsA patients (55% male; 53...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27538766/utility-of-ultrasonography-in-guiding-modification-of-disease-modifying-anti-rheumatic-drugs-and-steroid-therapy-for-inflammatory-arthritis-in-routine-clinical-practice
#19
York Kiat Tan, Li-Ching Chew, John C Allen, Weng Kit Lye, Lei Lei Htay, Ali Hassan, Philip G Conaghan, Julian Thumboo
OBJECTIVE: To determine the utility of ultrasonography in guiding modification of disease-modifying anti-rheumatic drug (DMARD) and steroid therapy for inflammatory arthritis (IA) in routine clinical practice. METHODS: In this retrospective study, we analyzed DMARD and steroid use in IA patients referred to a rheumatologist-led ultrasound clinic. Power Doppler (PD) vascularity and greyscale (GS) synovial hypertrophy joint findings were categorized as positive/negative for each patient...
August 19, 2016: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/27522710/-hepatobiliary-system-diseases-as-the-predictors-of-psoriasis-progression
#20
S V Smirnova, A A Barilo, M V Smolnikova
PURPOSE OF THE STUDY: To assess the state of the hepatobiliary system in psoriasis andpsoriatic arthritis in order to establish a causal relationship and to identify clinical and functional predictors of psoriatic disease progression. METHODS: The study includedpatients with extensive psoriasis vulgaris (n = 175) aged 18 to 66 years old and healthy donors (n = 30), matched by sex and age: Group 1--patients with psoriasis (PS, n = 77), group 2--patients with psoriatic arthritis (PsA, n = 98), group 3--control...
2016: Vestnik Rossiĭskoĭ Akademii Meditsinskikh Nauk
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