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Ultrasound + Vasculitis OR Gout OR enthesitis OR rheumatology

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https://www.readbyqxmd.com/read/27900348/implementation-of-musculoskeletal-ultrasonography-in-detection-of-early-juvenile-idiopathic-arthritis
#1
Ayman F Darwish, Faten M Ismael, Abdou Ell-Laban, Ahmed Hamed, Moustafa Abdel Kader, Ashraf Osman
AIM: To determine whether early clinical, laboratory and musculoskeletal ultrasound (MSUS) characteristics can be used as early detectors of juvenile idiopathic arthritis. PATIENTS AND METHODS: Forty (40) patients with juvenile idiopathic arthritis (JIA) diagnosed according to the ILAR criteria [1] and 20 healthy control children. All patients were subjected to the following assessment at base line and at follow up after 6 months: Clinical evaluation, MSUS examination and laboratory evaluation...
2016: European Journal of Radiology Open
https://www.readbyqxmd.com/read/27900299/assessment-of-enthesitis-in-patients-with-psoriatic-arthritis-using-clinical-examination-and-ultrasound
#2
Salome Kristensen, Jeppe Hagstrup Christensen, Erik Berg Schmidt, Jens Lykkegaard Olesen, Martin Berg Johansen, Kristian Bakke Arvesen, Annette Schlemmer
BACKGROUND: Enthesitis is a major feature of psoriatic arthritis. However, clinical assessment of enthesitis is known to lack accuracy and have poor interobserver reliability. OBJECTIVE: To determine effect of training on clinical assessment of enthesitis and to compare ultrasonography with clinical examination for the detection of entheseal abnormalities. METHODS: 20 rheumatologists performed repeated assessment of enthesitis in patients with established psoriatic arthritis before and after a 2-hour training session in standardised enthesitis count according to Leeds Enthesitis Index (LEI) and Spondyloarthritis Research Consortium of Canada Enthesitis Index (SPARCC)...
April 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27896522/tapering-biologics-in-rheumatoid-arthritis-a-pragmatic-approach-for-clinical-practice
#3
Aleksander Lenert, Petar Lenert
Optimal rheumatoid arthritis (RA) therapy in daily clinical practice is based on the treat-to-target strategy. Quicker escalation of therapy and earlier introduction of biological disease-modifying anti-rheumatic drugs have led to improved outcomes in RA. However, chronic immunosuppressive therapy is associated with adverse events and higher costs. In addition, our patients frequently express a desire for lower dosing and drug holidays. Current clinical practice guidelines from the American College of Rheumatology and European League Against Rheumatism suggest that rheumatologists consider tapering treatment after achieving remission...
November 28, 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27867432/arthritis-of-the-knee-joint-in-rheumatoid-arthritis-evaluation-of-treatment-response-by-ultrasound-in-daily-clinical-practice
#4
V S Schäfer, W A Schmidt, M Backhaus, W Hartung
BACKGROUND: Rheumatoid arthritis (RA) commonly involves the knee joint in up to 30% of patients. Musculoskeletal ultrasound enables the skilled clinician to easily assess disease activity. OBJECTIVE: To evaluate the sensitivity to change of the sonography score of large joints in Rheumatology (SOLAR) for different treatments of knee arthritis in RA. METHOD: Joints were assessed by ultrasound at 4 visits. Laboratory, immunological and clinical parameters were recorded...
2016: Open Rheumatology Journal
https://www.readbyqxmd.com/read/27860304/nail-involvement-can-predict-enthesopathy-in-patients-with-psoriasis
#5
Maria Castellanos-González, Beatriz Esther Joven, Julio Sánchez, Eva María Andrés-Esteban, Francisco Vanaclocha-Sebastián, Pablo Ortiz Romero, Raquel Rivera Díaz
BACKGROUND: Although subclinical enthesopathy is a well-established diagnostic criterion for psoriatic arthritis (PsA), it is frequently overlooked, as many patients are asymptomatic. The possibility of finding a clinical clue predicting enthesopathy would help clinicians establish an early diagnosis of PsA. MATERIAL AND METHODS: A prospective single-center study of a total of 90 patients with psoriasis was conducted to assess the presence of entheseal abnormalities as detected by ultrasound, and to determine any correlation with nail involvement...
November 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/27848057/the-additional-benefit-of-ultrasonography-to-2010-acr-eular-classification-criteria-when-diagnosing-rheumatoid-arthritis-in-the-absence-of-anti-cyclic-citrullinated-peptide-antibodies
#6
Lanlan Ji, Xuerong Deng, Yan Geng, Zhibo Song, Zhuoli Zhang
The aim of this study was to assess the benefit of ultrasonography (US) contributing to 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria in diagnosing rheumatoid arthritis (RA), when anti-citrullinated protein (CCP) antibody and radiographic erosions are absent. Ninety-four patients suffering from arthritis of at least one joint in hands, symptom duration of less than 2 years, normal radiographs at baseline, and negative anti-CCP had 22 joint US assessments and were followed prospectively for at least 12 months...
November 15, 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27837195/joint-ultrasound-baseline-abnormalities-predict-a-specific-long-term-clinical-outcome-in-systemic-lupus-erythematosus-patients
#7
P Corzo, T C Salman-Monte, V Torrente-Segarra, L Polino, S Mojal, J Carbonell-Abelló
OBJECTIVE: To describe long-term clinical and serological outcome in all systemic lupus erythematosus (SLE) domains in SLE patients with hand arthralgia (HA) and joint ultrasound (JUS) inflammatory abnormalities, and to compare them with asymptomatic SLE patients with normal JUS. METHODS: SLE patients with HA who presented JUS inflammatory abnormalities ('cases') and SLE patients without HA who did not exhibit JUS abnormalities at baseline ('controls') were included...
November 10, 2016: Lupus
https://www.readbyqxmd.com/read/27832792/gout-will-the-king-of-diseases-be-the-first-rheumatic-disease-to-be-cured
#8
EDITORIAL
Jasvinder A Singh
Gout is the most common inflammatory arthritis in adults in the Western world. Characterized by hyperuricemia and the effects of acute and chronic inflammation in joints and bursa, gout leads to an agonizing, chronically painful arthritis. Arthritis can also be accompanied by urate nephropathy and subcutaneous urate deposits (tophi). Exciting new developments in the last decade have brought back the focus on this interesting, crystal-induced chronic inflammatory condition. New insights include the role of NALP3 inflammasome-induced inflammation in acute gout, the characterization of diagnostic signs on ultrasound and dual-energy computed tomography imaging modalities, the recognition of target serum urate less than 6 mg/day as the goal for urate-lowering therapies, and evidence-based treatment guidelines...
November 11, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27830422/isolated-breast-vasculitis-manifested-as-breast-edema-with-suggestive-sonographic-findings-a-case-report-with-imaging-findings
#9
Ji Young Lee, Mee Joo
Early diagnosis of breast vasculitis (BV) is difficult because this condition is rare and occasionally mimics breast cancer clinically or radiologically. It may present as systemic disease or as an isolated lesion in the breast, without systemic evidence. When vasculitis appears in the breast, it also might manifest as a tumor-like lesion, and in previous cases, tissue acquisition was needed for confirmation of the diagnosis because of BV's resemblance to inflammatory breast cancer. We report a case of isolated BV that was suspected of being inflammatory breast cancer clinically, but manifested as bilateral breast edema on mammography...
November 9, 2016: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/27826182/amaurosis-fugax-risk-factors-and-prevalence-of-significant-carotid-stenosis
#10
Pia Kvickström, Bertil Lindblom, Göran Bergström, Madeleine Zetterberg
PURPOSE: The purpose of this study was to describe clinical characteristics and prevalence of carotid stenosis in patients with amaurosis fugax (AF). METHOD: Patients diagnosed with AF and subjected to carotid ultrasound in 2004-2010 in Sahlgrenska University Hospital, Gothenburg (n=302), were included, and data were retrospectively collected from medical records. RESULTS: The prevalence of significant carotid stenosis was 18.9%, and 14.2% of the subjects were subjected to carotid endarterectomy...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27801338/-the-correlations-of-single-photon-emission-computed-tomography-joints-scan-and-bone-metabolic-markers-in-active-rheumatoid-arthritis
#11
H Y Gao, X F Li, B N Zhang, M H Ding, D S Zhao
Objective: To explore the correlation between quantitative value of joint bone scan by single photon emission computed tomography(SPECT) and serum bone metabolic markers in patients with active rheumatoid arthritis(RA). Method: Clinical data of 60 newly diagnosed RA patients were retrospectively collected in Department of Rheumatology and Immunology from May 2013 to December 2014, including 28 cases with medical history less than 6 months and 32 from 6 months to 2 years. Serum C-terminal telopeptide of type Ⅰ collgen(CTX-Ⅰ)and N-terminal propeptide of type Ⅰ collagen(PINP)were tested by chemiluminesence...
November 1, 2016: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/27796481/-imaging-options-in-pediatric-rheumatology
#12
D Windschall
There has been growing interest in the use of imaging modalities in pediatric rheumatology for the past 15 years. Nowadays, highly sensitive imaging techniques can be used to detect early stages of pediatric rheumatic diseases in addition to the physical examination. Magnetic resonance imaging and musculoskeletal ultrasound play the most important role. Moreover, these two techniques are of great value in differential diagnostics and therapy monitoring. The use of imaging methods with a high radiation exposure could therefore be greatly reduced over the last decade...
December 2016: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/27749228/adding-ultrasound-to-clinical-examination-reduced-frequency-of-enthesitis-in-primary-care-psoriasis-patients-with-musculoskeletal-complaints
#13
Myrthe van der Ven, Maren C Karreman, Angelique E A M Weel, Ilja Tchetverikov, Marijn Vis, Tamar E C Nijsten, Johanna M W Hazes, Jolanda J Luime
OBJECTIVES: Part of the psoriasis patients with musculoskeletal complaints will have inflammation of the entheses. Entheseal inflammation is difficult to assess by clinical examination only. Therefore, we aimed to determine the frequency of clinically relevant ultrasound inflammation at the most commonly assessed entheses (MASEI; Madrid Sonographic Enthesis Index) in primary care psoriasis patients with one or more tender entheses. METHODS: Adult primary care psoriasis patients with musculoskeletal complaints (tender enthesis or arthritis at physical examination) had an ultrasound examination of seven entheses according to the MASEI...
September 8, 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27748084/performance-of-ultrasound-in-the-diagnosis-of-gout-in-a-multi-center-study-comparison-with-monosodium-urate-crystal-analysis-as-the-gold-standard
#14
Alexis Ogdie, William J Taylor, Tuhina Neogi, Jaap Fransen, Tim L Jansen, H Ralph Schumacher, Worawit Louthrenoo, Janitzia Vazquez-Mellado, Maxim Eliseev, Geraldine McCarthy, Lisa K Stamp, Fernando Perez-Ruiz, Francisca Sivera, Hang-Korng Ea, Martijn Gerritsen, Giovanni Cagnotto, Lorenzo Cavagna, Chingtsai Lin, Yin-Yi Chou, Anne-Kathrin Tausche, Manuella Lima Gomes Ochtrop, Matthijs Janssen, Jiunn-Horng Chen, Ole Slot, Juris Lazovskis, Douglas White, Marco A Cimmino, Till Uhlig, Nicola Dalbeth
OBJECTIVES: To examine the performance of ultrasound for the diagnosis of gout using presence of monosodium urate (MSU) crystals as the gold standard. METHODS: We analyzed data from the Study for Updated Gout Classification Criteria (SUGAR), a large, multi-center observational cross-sectional study of consecutive subjects with at least one swollen joint who conceivably may have gout. All subjects underwent arthrocentesis; cases were subjects with MSU crystal confirmation...
October 16, 2016: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/27748075/the-sound-and-the-fury-musculoskeletal-ultrasound-in-the-diagnosis-of-gout
#15
Eugene Y Kissin, Michael H Pillinger
No abstract text is available yet for this article.
October 16, 2016: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/27742022/imaging-for-synovitis-acne-pustulosis-hyperostosis-and-osteitis-sapho-syndrome
#16
Steven Schaub, Hartley M Sirkis, Jonathan Kay
Multifocal osteomyelitis and synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome constitute a spectrum of disease that includes inflammatory bone lesions and dermatologic findings. Radiographic features resemble those of the spondyloarthropathies with anterior chest wall involvement. Early radiographic findings are osteodestructive with lytic lesions. Bone scintigraphy of the sternoclavicular region classically yields a 'bull's head' pattern of radionuclide uptake. Magnetic resonance imaging (MRI) can demonstrate corner lesions of vertebral bodies...
November 2016: Rheumatic Diseases Clinics of North America
https://www.readbyqxmd.com/read/27742018/imaging-in-gout-and-other-crystal-related-arthropathies
#17
Patrick Omoumi, Pascal Zufferey, Jacques Malghem, Alexander So
In this article, the authors consider the manifestations of intraarticular and periarticular crystal deposits. Most cases of crystal deposits are asymptomatic and represent incidental findings at imaging. In symptomatic arthropathies, imaging can play an important role in the diagnosis and assessment of disease progression and the extent of crystal deposits. Conventional radiography is the most common imaging modality. But ultrasound, conventional computerized tomography (CT), dual-energy CT, and MRI play an increasing role...
November 2016: Rheumatic Diseases Clinics of North America
https://www.readbyqxmd.com/read/27716316/ultrasonographic-assessment-of-bone-erosions-in-the-different-subtypes-of-systemic-lupus-erythematosus-arthritis-comparison-with-computed-tomography
#18
Matteo Piga, Luca Saba, Alessandra Gabba, Mattia Congia, Antonella Balestrieri, Alessandro Mathieu, Alberto Cauli
BACKGROUND: The aim was to determine the accuracy of high-resolution ultrasonography (US) for detecting erosion in the metacarpophalangeal (MCP) and wrist joints of patients with different subtypes of systemic lupus erythematosus (SLE) arthritis, using computed tomography (CT) as the gold-standard reference method. METHOD: The ulnar head, radiocarpal and second to fifth MCP joints in 26 patients with SLE - 9 classified as having rhupus syndrome, 10 as having Jaccoud's arthropathy (JA) and 7 as having non-deforming non-erosive (NDNE) arthritis - were subdivided into areas and bilaterally evaluated for the presence of bone erosion by CT and US...
October 4, 2016: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/27687483/hand-osteoarthritis-current-knowledge-and-new-ideas
#19
I K Haugen
Hand osteoarthritis (OA) is a prevalent disease that can lead to substantial pain and physical disability. Currently, no disease-modifying drugs exist for the treatment of OA. Most OA research has been conducted on knee OA and we have limited knowledge about disease mechanisms in hand OA. During her research career, Ida K Haugen (IKH) has focused on the epidemiology of hand OA and imaging techniques. She has established a large international network, providing the opportunity to study the epidemiology of hand OA in large international OA cohorts...
August 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27679727/imaging-of-juvenile-idiopathic-arthritis-part-ii-ultrasonography-and-mri
#20
REVIEW
Iwona Sudoł-Szopińska, Elżbieta Grochowska, Piotr Gietka, Mateusz Płaza, Grzegorz Pracoń, Fadhil Saied, Marta Walentowska-Janowicz
Juvenile idiopathic arthritis is the most common autoimmune systemic disease of the connective tissue affecting individuals in the developmental age. Radiography, which was described in the first part of this publication, is the standard modality in the assessment of this condition. Ultrasound and magnetic resonance imaging enable early detection of the disease which affects soft tissues, as well as bones. Ultrasound assessment involves: joint cavities, tendon sheaths and bursae for the presence of synovitis, intraand extraarticular fat tissue to visualize signs of inflammation, hyaline cartilage, cartilaginous epiphysis and subchondral bone to detect cysts and erosions, and ligaments, tendons and their entheses for signs of enthesopathies and tendinopathies...
September 2016: Journal of Ultrasonography
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