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https://www.readbyqxmd.com/read/29328413/prevalence-of-the-cyp2c19-2-681-g-a-3-636-g-a-and-17-%C3%A2-806-c-t-alleles-among-an-iranian-population-of-different-ethnicities
#1
Mahshid Dehbozorgi, Behnam Kamalidehghan, Iman Hosseini, Zahra Dehghanfard, Mohammad Hossein Sangtarash, Maryam Firoozi, Fatemeh Ahmadipour, Goh Yong Meng, Massoud Houshmand
Polymorphisms in the cytochrome P (CYP) 450 family may cause adverse drug responses in individuals. Cytochrome P450 2C19 (CYP2C19) is a member of the CYP family, where the presence of the 681 G>A, 636 G>A and 806 C>T polymorphisms result in the CYP2C19*2, CYP2C19*3 and CYP2C19*17 alleles, respectively. In the current study, the frequency of the CYP2C19*2, CYP2C19*3 and CYP2C19*17 alleles in an Iranian population cohort of different ethnicities were examined and then compared with previously published frequencies within other populations...
January 5, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29304156/engaging-in-extreme-activism-in-support-of-others-political-struggles-the-role-of-politically-motivated-fusion-with-out-groups
#2
Jonas R Kunst, Beverly Boos, Sasha Y Kimel, Milan Obaidi, Maor Shani, Lotte Thomsen
Humans are a coalitional, parochial species. Yet, extreme actions of solidarity are sometimes taken for distant or unrelated groups. What motivates people to become solidary with groups to which they do not belong originally? Here, we demonstrate that such distant solidarity can occur when the perceived treatment of an out-group clashes with one's political beliefs (e.g., for Leftists, oppressive occupation of the out-group) and that it is driven by fusion (or a feeling of oneness) with distant others with whom one does not share any common social category such as nationality, ethnicity or religion...
2018: PloS One
https://www.readbyqxmd.com/read/29229157/long-term-outcomes-of-sigmoid-diverticulitis-a-single-center-experience
#3
Ido Mizrahi, Abbas Al-Kurd, Katya Chapchay, Yael Ag-Rejuan, Natalia Simanovsky, Ahmed Eid, Haggi Mazeh
BACKGROUND: During the last decade, guidelines for the treatment of sigmoid diverticulitis have dramatically changed. The aim of this study is to report the long-term outcomes of patients treated for diverticulitis at a nonspecialized single center. MATERIALS AND METHODS: After obtaining institutional review board approval, medical records of all patients admitted to our institution with the diagnosis of sigmoid diverticulitis between 1998 and 2008 were reviewed...
January 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29215496/comparing-health-related-quality-of-life-outcomes-in-patients-undergoing-either-primary-or-revision-anterior-cervical-discectomy-and-fusion
#4
Gregory D Schroeder, Barrett S Boody, Christopher K Kepler, Mark F Kurd, Stephen Silva, Kristen Nicholson, Jefferson R Wilson, Barret I Woods, Kris E Radcliff, D Greg Anderson, Alan S Hilibrand, Alexander R Vaccaro, Jeffery A Rihn
STUDY DESIGN: A retrospective review of prospectively collected data. OBJECTIVE: Compare HRQOL outcome metrics in patients undergoing primary and revision ACDF. SUMMARY OF BACKGROUND DATA: Anterior cervical discectomy and fusion (ACDF) is associated with significant improvements in health related quality of life (HRQOL) outcome metrics. However, 2.9% of patients per year will develop symptomatic adjacent segment disease and there is a paucity of literature on HRQOL outcomes following revision ACDF...
December 5, 2017: Spine
https://www.readbyqxmd.com/read/29204778/conversion-of-laparoscopic-adjustable-gastric-banding-to-gastric-bypass-a-comparison-to-primary-gastric-bypass
#5
Abbas Al-Kurd, Ronit Grinbaum, Ala'a Abubeih, Baha Siam, Muhammad Ghanem, Haggi Mazeh, Ido Mizrahi, Nahum Beglaibter
INTRODUCTION: Laparoscopic adjustable gastric banding (LAGB) has a considerable failure rate. Laparoscopic Roux-en-Y gastric bypass (LRYGB) is one of the rescue options. This study aims to compare the complication rates and outcomes between LAGB converted to LRYGB and primary LRYGB. MATERIALS AND METHODS: A retrospective analysis was performed in all patients converted from LAGB to LRYGB between January 2007 and March 2017. This group was compared to a matched cohort of primary LRYGB patients operated during the same period...
December 4, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29153745/analysis-of-the-golden-proportion-and-width-height-ratios-of-maxillary-anterior-teeth-in-arab-and-kurdish-populations
#6
Neda Al-Kaisy, Balkees Taha Garib
STATEMENT OF PROBLEM: Dentists providing anterior restorations are guided by the principles of anatomic tooth dimension. Dental biometrics should consider ethnicity to produce a more comprehensive evaluation. PURPOSE: The purpose of this clinical study was to analyze the anatomic crowns of maxillary central incisors (CI), lateral incisors (LI), and canines (C) with respect to the golden proportion (GP) and width/height (W/H) ratio in Kurdish and Arab populations...
November 15, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/29099847/a-glimpse-at-the-intricate-mosaic-of-ethnicities-from-mesopotamia-paternal-lineages-of-the-northern-iraqi-arabs-kurds-syriacs-turkmens-and-yazidis
#7
Serkan Dogan, Cemal Gurkan, Mustafa Dogan, Hasan Emin Balkaya, Ramazan Tunc, Damla Kanliada Demirdov, Nihad Ahmed Ameen, Damir Marjanovic
Widely considered as one of the cradles of human civilization, Mesopotamia is largely situated in the Republic of Iraq, which is also the birthplace of the Sumerian, Akkadian, Assyrian and Babylonian civilizations. These lands were subsequently ruled by the Persians, Greeks, Romans, Arabs, Mongolians, Ottomans and finally British prior to the independence. As a direct consequence of this rich history, the contemporary Iraqi population comprises a true mosaic of different ethnicities, which includes Arabs, Kurds, Turkmens, Assyrians, and Yazidis among others...
2017: PloS One
https://www.readbyqxmd.com/read/29095412/cervical-sagittal-range-of-motion-as-a-predictor-of-symptom-severity-in-cervical-spondylotic-myelopathy
#8
Kristen J Nicholson, Paul W Millhouse, Emily Pflug, Barrett Woods, Gregory D Schroeder, D Greg Anderson, Alan S Hilibrand, Christopher K Kepler, Mark F Kurd, Jeffrey A Rihn, Alexander Vaccaro, Kris E Radcliff
STUDY DESIGN: Retrospective review of radiographic data and functional outcomes. OBJECTIVE: Evaluate whether myelopathy symptom severity upon presentation corresponds to sagittal plane alignment or non-myelopathy symptoms, such as pain, in patients with cervical spondylotic myelopathy (CSM). SUMMARY OF BACKGROUND DATA: Cervical sagittal balance is an important parameter in the outcome of surgical reconstruction. However, the effect of sagittal alignment on symptom severity in patients who have not undergone spine surgery is not well defined...
October 31, 2017: Spine
https://www.readbyqxmd.com/read/29028759/which-domains-of-the-odi-best-predict-change-in-physical-function-in-patients-after-surgery-for-degenerative-lumbar-spondylolisthesis
#9
Hamadi A Murphy, Eugene Warnick, Richard McGintee, Kristen Nicholson, Douglas A Hollern, Christie Stawicki, Daniel Tarazona, Gregory D Schroeder, Barrett I Woods, Mark F Kurd, Jeffrey A Rihn, Greg D Anderson, Christopher K Kepler, Alan S Hilibrand, Alexander R Vaccaro, Kris E Radcliff
STUDY DESIGN: Retrospective Review OBJECTIVE.: The purpose of this study is to determine the differential improvement of the various individual items of the ODI and to determine their relationship to other measures of HRQOL. SUMMARY OF BACKGROUND DATA: The oswestry disability index (ODI) is an easily scored, common, ten-item questionnaire about symptoms relevant to lumbar spine pathology. It is not clear if all of the items can be reliably applied to spine surgery...
October 12, 2017: Spine
https://www.readbyqxmd.com/read/28989838/sacral-fractures-and-associated-injuries
#10
REVIEW
Ricardo Rodrigues-Pinto, Mark F Kurd, Gregory D Schroeder, Christopher K Kepler, James C Krieg, Jörg H Holstein, Carlo Bellabarba, Reza Firoozabadi, F Cumhur Oner, Frank Kandziora, Marcel F Dvorak, Conor P Kleweno, Luiz R Vialle, S Rajasekaran, Klause J Schnake, Alexander R Vaccaro
STUDY DESIGN: Literature review. OBJECTIVE: The aim of this review is to describe the injuries associated with sacral fractures and to analyze their impact on patient outcome. METHODS: A comprehensive narrative review of the literature was performed to identify the injuries associated with sacral fractures. RESULTS: Sacral fractures are uncommon injuries that result from high-energy trauma, and that, due to their rarity, are frequently underdiagnosed and mistreated...
October 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28899376/perceptions-about-iranian-kurds-ethnic-inequality-in-health
#11
Arezoo Yari, Saharnaz Nedjat, Mohsen Asadi-Lari, Reza Majdzadeh
BACKGROUND: Evidence shows ethnic-inequality is a very effective variable in the Community and individual health associated outcomes. This study focused on gaining a deeper understanding of people's perception on inequality of health in Iranian-Kurds and its determinants. METHODS: The study was conducted in the three cities of Marivan, Sanandaj (capital of Kurdistan province in Iran) and Tehran (capital of the country). The study was conducted through 34 in-depth interviews and ten focus group discussions with health services users, academic graduates and health delivery service personnel...
September 12, 2017: BMC International Health and Human Rights
https://www.readbyqxmd.com/read/28816880/management-of-hangman-s-fractures-a-systematic-review
#12
Hamadi Murphy, Gregory D Schroeder, Weilong J Shi, Christopher K Kepler, Mark F Kurd, Andrew N Fleischman, Frank Kandziora, Jens R Chapman, Lorin M Benneker, Alexander R Vaccaro
BACKGROUND: Traumatic spondylolisthesis of the axis, is a common cervical spine fracture; however, to date there is limited data available to guide the treatment of these injuries. The purpose of this review is to provide an evidence-based analysis of the literature and clinical outcomes associated with the surgical and nonsurgical management of hangman's fractures. METHODS: A systematic literature search was conducted using PubMed (MEDLINE) and Scopus (EMBASE, MEDLINE, COMPENDEX) for all articles describing the treatment of hangman's fractures in 2 or more patients...
September 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28627831/whole-blood-thiopurine-s-methyltransferase-genotype-and-phenotype-concordance-in-iranian-kurdish-ulcerative-colitis-uc-patients
#13
Fariborz Bahrehmand, Asad Vaisi-Raygani, Amir Kiani, Homayoun Bashiri, Mahdi Zobeiri, Maryam Tanhapour, Tayebeh Pourmotabbed
BACKGROUND: Thiopurine methyl transferase (TPMT), a drug-metabolizing enzyme, catalyzes methylation and consequently, the metabolism of thiopurine compounds used for treatment of inflammatory bowel disease (IBD). Individuals who are homozygous recessive or have extremely low TPMT activity need to avoid thiopurines because of concern for significant leukopenia. The aim of this research was to determine TPMT phenotypes and genotypes in IBD patients to predict the risk of thiopurine toxicity before treatment...
May 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28423177/comparison-of-appendectomy-outcomes-between-senior-general-surgeons-and-general-surgery-residents
#14
COMPARATIVE STUDY
Baha Siam, Abbas Al-Kurd, Natalia Simanovsky, Haitham Awesat, Yahav Cohn, Brigitte Helou, Ahmed Eid, Haggi Mazeh
Importance: In some centers, the presence of a senior general surgeon (SGS) is obligatory in every procedure, including appendectomy, while in others it is not. There is a relative paucity in the literature of reports comparing the outcomes of appendectomies performed by unsupervised general surgery residents (GSRs) with those performed in the presence of an SGS. Objective: To compare the outcomes of appendectomies performed by SGSs with those performed by GSRs...
July 1, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28291765/cervical-spine-surgery-complications-and-risks-in-the-elderly
#15
Kris Radcliff, Kevin L Ong, Scott Lovald, Edmund Lau, Mark Kurd
STUDY DESIGN: Cervical decompression (CD) and cervical fusion (CF) patients in 5% Medicare Part B claims data. OBJECTIVE: Evaluate the complication rate and associated risk factors after cervical spine surgery using a national sample of elderly patients. SUMMARY OF BACKGROUND DATA: The number of cervical spine procedures in the United States has risen along with associated hospital costs. Postoperative complications lead to longer hospitalizations and greater costs...
March 15, 2017: Spine
https://www.readbyqxmd.com/read/28291143/the-role-of-multimodal-analgesia-in-spine-surgery
#16
REVIEW
Mark F Kurd, Tyler Kreitz, Gregory Schroeder, Alexander R Vaccaro
Optimal postoperative pain control allows for faster recovery, reduced complications, and improved patient satisfaction. Historically, pain management after spine surgery relied heavily on opioid medications. Multimodal regimens were developed to reduce opioid consumption and associated adverse effects. Multimodal approaches used in orthopaedic surgery of the lower extremity, especially joint arthroplasty, have been well described and studies have shown reduced opioid consumption, improved pain and function, and decreased length of stay...
April 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28284203/factors-associated-with-cervical-cancer-screening-participation-among-immigrants-of-russian-somali-and-kurdish-origin-a-population-based-study-in-finland
#17
Esther E Idehen, Tellervo Korhonen, Anu Castaneda, Teppo Juntunen, Mari Kangasniemi, Anna-Maija Pietilä, Päivikki Koponen
BACKGROUND: Previous studies revealed low participation in cervical cancer screening among immigrants compared with non-immigrants. Only a few studies about factors associated with immigrants' lower participation rates have been conducted in European countries that have universal access for all eligible women. Our study aimed to explore factors associated with cervical screening participation among women of Russian, Somali, and Kurdish origin in Finland. METHODS: We used data from the Migrant Health and Well-being Survey, 2010-2012...
March 11, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28180013/the-influence-of-internal-wall-and-floor-covering-materials-and-ventilation-type-on-indoor-radon-and-thoron-levels-in-hospitals-of-kermanshah-iran
#18
Meghdad Pirsaheb, Farid Najafi, Abbas Haghparast, Lida Hemati, Kiomars Sharafi, Nematullah Kurd
BACKGROUND: Building materials and the ventilation rate of a building are two main factors influencing indoor radon and thoron levels (two radioactive gases which have the most important role in human natural radiation exposure within dwellings). OBJECTIVES: This analytical descriptive study was intended to determine the relationship between indoor radon and thoron concentrations and the building materials used in interior surfaces, as well as between those concentrations and the type of ventilation system (natural or artificial)...
October 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28114347/genetic-hla-study-of-kurds-in-iraq-iran-and-tbilisi-caucasus-georgia-relatedness-and-medical-implications
#19
Antonio Arnaiz-Villena, Jose Palacio-Grüber, Ester Muñiz, Cristina Campos, Javier Alonso-Rubio, Eduardo Gomez-Casado, Shadallah Fareq Salih, Manuel Martin-Villa, Rawand Al-Qadi
Kurds from Iraq (Dohuk and Erbil Area, North Iraq) have been analyzed for HLA genes. Their HLA genetic profile has been compared with that of other Kurd groups from Iran and Tbilisi (Georgia, Caucasus) and also Worldwide populations. A total of 7,746 HLA chromosomes have been used. Genetic distances, NJ dendrograms and correspondence analyses have been carried out. Haplotype HLA-B*52-DRB1*15 is present in all three analyzed Kurd populations. HLA-A*02-B*51-DRB1*11 is present in Iraq and Georgia Kurds. Haplotypes common to Iran and Iraq Kurds are HLA DRB1*11-DQB1*03, HLA DRB1*03-DQB1*02 and others in a lower frequency...
2017: PloS One
https://www.readbyqxmd.com/read/28108130/contribution-of-sociodemographic-and-lifestyle-related-factors-to-the-differences-in-metabolic-syndrome-among-russian-somali-and-kurdish-migrants-compared-with-finns
#20
N Skogberg, T Laatikainen, A Jula, T Härkänen, E Vartiainen, P Koponen
BACKGROUND: Metabolic syndrome (MetS) is associated with a substantially increased risk for cardiovascular disease and diabetes. We examined the contribution of length of residence, socioeconomic position and lifestyle-related factors to the differences in the prevalence of MetS among migrants compared with Finns. METHODS: Cross-sectional data from randomly sampled 30-64year-old health examination participants (318 Russian, 212 Somali, and 321 Kurdish origin migrants) of the Migrant Health and Wellbeing Survey (2010-2012) were used...
January 10, 2017: International Journal of Cardiology
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