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https://www.readbyqxmd.com/read/28210435/role-of-thr399ile-and-asp299gly-polymorphisms-of-toll-like-receptor-4-gene-in-acute-dental-abscess
#1
Ebrahim Miri-Moghaddam, Narges Farhad-Mollashahi, Elnaz Baghaee, Ali Bazi, Yasaman Garme
BACKGROUND: Apical Periodontitis (AP) is an inflammatory disease that affects the tissues surrounding the root end of a tooth. The disease which is caused by endodontic infections presents in different clinical ways including development of an acute abscess. Recent studies have provided information suggesting role of a multitude of factors in pathogenesis of acute apical abscess (AAA). In this case-control study, our goal was to evaluate the frequency and potential role of two common polymorphisms of toll like receptor-4 (TLR-4) gene; Thr399Ile (1196 C>T) and Asp299Gly (+896 A>G), in 50 patients with AAA as cases and 50 patients with asymptomatic apical periodontitis (AAP) as controls...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28193226/hair-growth-promoting-effect-of-geranium-sibiricum-extract-in-human-dermal-papilla-cells-and-c57bl-6-mice
#2
William A Boisvert, Miri Yu, Youngbin Choi, Gi Hee Jeong, Yi-Lin Zhang, Sunghun Cho, Changsun Choi, Sanghyun Lee, Bog-Hieu Lee
BACKGROUND: Geranium sibiricum L. has been used as a medicinal plant to treat diarrhea, bacterial infection, and cancer in Bulgaria, Peru, and Korea. However, its hair growth-promoting effect was not investigated so far. This study examined the effects of Geranium sibiricum L. extract (GSE) on hair growth, using in vitro and in vivo models. METHODS: Antioxidant, proliferation and migration assay of GSE was performed with human dermal papilla cells (hDPCs). Hair-growth promoting effect was measured in animal model...
February 13, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28161403/factors-affecting-the-distribution-of-haemosporidian-parasites-within-an-oceanic-island
#3
David P Padilla, Juan Carlos Illera, Catalina Gonzalez-Quevedo, Miry Villalba, David S Richardson
Understanding how different ecological and evolutionary processes influence the distribution of pathogens within the environment is important from many perspectives including wildlife epidemiology, evolutionary ecology and conservation. The simultaneous use of ecological and evolutionary frameworks can enhance our conceptual understanding of host-parasite interactions, however such studies are rare in the wild. Using samples from 12 bird species caught across all habitats existing on an oceanic island, we evaluated how environmental variables, parasite host specificity and parasite phylogenetic relationships determine the distribution and prevalence of haemosporidians (Haemoproteus, Plasmodium and Leucocytozoon) in the wild living avifauna...
February 2, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/28157325/deposition-and-characterization-of-roughened-surfaces
#4
Hagit Aviv, Shirly Berezin, Ortal Agai, Miri Sinwani, Yaakov R Tischler
Phase separation occurs whenever a solvent leaves a solution of strongly incompatible polymers. This can happen in a bulk and in films. Films can be tailored as substrates for multiple applications, such as solar cells, surface catalysis, and anti-reflection coatings. In this research, polystyrene (PS) was dissolved with polyvinyl acetate (PVAc) in a few different ratios using chlorobenzene as the solvent. Thin films of the different ratios were deposited on glass via spin coating. The deposited films were investigated for morphology, strain, surface area and Raman scattering...
February 3, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28156098/accurate-and-precise-determination-of-mechanical-properties-of-silicon-nitride-beam-nanoelectromechanical-devices
#5
Hakseong Kim, Dong Hoon Shin, Kirstie McAllister, Miri Seo, Sangik Lee, Il-Suk Kang, Bae Ho Park, Eleanor E B Campbell, Sang Wook Lee
Accurate and precise determination of mechanical properties of nanoscale materials is mandatory since device performances of nanoelectromechanical systems (NEMS) are closely related to the flexural properties of the materials. In this study, the intrinsic mechanical properties of highly stressed silicon nitride (SiN) beams of varying lengths are investigated using two different techniques: Dynamic flexural measurement using optical interferometry and quasi-static flexural measurement using atomic force microscopy...
February 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28144117/a-monte-carlo-study-on-quantifying-the-amount-of-dose-reduction-by-shielding-the-superficial-organs-of-an-iranian-11-year-old-boy
#6
Parisa Akhlaghi, Elie Hoseinian-Azghadi, Hashem Miri-Hakimabad, Laleh Rafat-Motavalli
A method for minimizing organ dose during computed tomography examinations is the use of shielding to protect superficial organs. There are some scientific reports that usage of shielding technique reduces the surface dose to patients with no appreciable loss in diagnostic quality. Therefore, in this Monte Carlo study based on the phantom of a 11-year-old Iranian boy, the effect of using an optimized shield on dose reduction to body organs was quantified. Based on the impact of shield on image quality, lead shields with thicknesses of 0...
October 2016: Journal of Medical Physics
https://www.readbyqxmd.com/read/28139773/large-variation-of-magnetic-properties-of-amorphous-fe-zr-thin-films-with-ar-pressure-during-sputtering
#7
Miri Kim, Nark-Eon Sung, Sang Ho Lim
A large change is observed in the magnetic properties of amorphous Fe-Zr thin films sputtered at different Ar pressures. The change depends on the composition of the alloys and at compositions near 60 at.% Fe, for example, the magnetisation measured at 10 kOe increases 30-fold with an increase in the Ar pressure from 2 to 10 mTorr. The magnetic properties are well explained by a combination of two phenomena-superparamagnetism and spin glass behaviours-and the large change is partly related to the number density of a magnetically correlated region...
January 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28133665/backbone-modified-oligonucleotides-for-tuning-the-cellular-uptake-behaviour-of-spherical-nucleic-acids
#8
Woo Chul Song, Kyoung-Ran Kim, Miri Park, Kyung Eun Lee, Dae-Ro Ahn
Spherical nucleic acids (SNAs) are spherically arranged oligonucleotides on core inorganic nanoparticles and have great potential for intracellular delivery of bioactive molecules, since they have been found to be internalized into mammalian cells. Understanding the factors that influence the cellular uptake of SNAs would be beneficial to design SNAs with novel uptake properties. We here report the effect of the sugar backbone type of the oligonucleotides on the cellular internalization of SNAs. After the preparation of SNAs with the oligonucleotides of five different sugar backbones, we analyze the cellular uptake efficiency quantitatively by flow cytometry and inductively coupled plasma mass spectrometry (ICP-MS)...
January 30, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28125098/assessment-of-human-milk-composition-using-mid-infrared-analyzers-requires-calibration-adjustment
#9
R Buffin, E Decullier, V De Halleux, C-M Loys, S Hays, F Studzinsky, E Jourdes, J Rigo, J-C Picaud
OBJECTIVE: Nutrient composition of human milk (HM) is highly variable. Targeted HM fortification has been proposed to address these variations and reduce the cumulative nutritional deficit in preterm infants. Near-infrared analysis is used to measure the protein and fat content in HM; however, the reliability of this technique has not been evaluated. The objective of this study is to evaluate the reproducibility and accuracy of two generations of HM analyzers (HMA1 and HMA2) in estimating protein and lipid contents...
January 26, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28123710/effects-of-propofol-on-myocardial-ischemia-reperfusion-injury-in-rats-with-type-2-diabetes-mellitus
#10
Ying Wang, Xiuru Qi, Chunliang Wang, Danning Zhao, Hongjie Wang, Jianxin Zhang
The current study aimed to examine the effects of propofol on myocardial ischemia-reperfusion injury (MIRI) in rats with type-2 diabetes mellitus (T2DM) and to assess the role of inflammatory mediators. Fifty healthy male adult Sprague-Dawley rats were randomly divided into the sham, ischemia-reperfusion (IR), IR plus low, middle and high-dose (6, 12 and 24 mg/kg/h, intravenous) propofol groups. The rats of all the groups were fed a high-sugar and high-fat diet for 8 weeks and streptozotocin (30 mg/kg, intraperitoneally) was used to establish the T2DM model...
January 2017: Biomedical Reports
https://www.readbyqxmd.com/read/28121747/relationship-between-some-single-nucleotide-polymorphism-and-response-to-hydroxyurea-therapy-in-iranian-patients-with-%C3%AE-thalassemia-intermedia
#11
Mehran Karimi, Tahereh Zarei, Sezaneh Haghpanah, Mohamad Moghadam, Ahmad Ebrahimi, Narges Rezaei, Ghazaleh Heidari, Afsaneh Vazin, Maryam Khavari, Hamid R Miri
OBJECTIVE: To evaluate the possible relationship between hydroxyurea (HU) response and some single-nucleotide polymorphism (SNP) in patients affected by β-thalassemia intermedia. MATERIALS AND METHODS: In this cross-sectional study, 100 β-thalassemia intermedia patients who were taking HU with a dose of 8 to 15 mg/kg body weight per day for a period of at least 6 months were randomly selected between February 2013 and October 2014 in southern Iran. HU response was defined based on decrease or cessation of the blood transfusion need and evaluation of Hb level...
January 24, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28120856/the-effect-of-l-arginine-supplementation-on-body-composition-and-performance-in-male-athletes-a-double-blinded-randomized-clinical-trial
#12
N Pahlavani, M H Entezari, M Nasiri, A Miri, M Rezaie, M Bagheri-Bidakhavidi, O Sadeghi
BACKGROUND/OBJECTIVE: Athletes used a lot of dietary supplements to achieve the more muscle mass and improve their athletic performance. The objective of this study was to investigate the effect of l-arginine supplementation on sport performance and body composition in male soccer players. SUBJECTS/METHODS: This double-blinded, randomized and placebo-controlled trial was conducted on 56 male soccer players, with age range of 16-35, who referred to sport clubs in Isfahan, Iran...
January 25, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28104557/a-comparative-study-on-capability-of-different-tree-species-in-accumulating-heavy-metals-from-soil-and-ambient-air
#13
Ahmad Alahabadi, Mohammad Hassan Ehrampoush, Mohammad Miri, Hamideh Ebrahimi Aval, Samira Yousefzadeh, Hamid Reza Ghaffari, Ehsan Ahmadi, Parvaneh Talebi, Zeynab Abaszadeh Fathabadi, Fatemeh Babai, Ali Nikoonahad, Kiomars Sharafi, Ahmad Hosseini-Bandegharaei
Heavy metals (HMs) in the urban environment can be bio-accumulated by plant tissues. The aim of this study was to compare fourteen different tree species in terms of their capability to accumulate four airborne and soilborne HMs including; zinc (Zn), copper (Cu), lead (Pb), and cadmium (Cd). Samplings were performed during spring, summer, and fall seasons. To compare bioaccumulation ability, bio-concentration factor (BCF), comprehensive bio-concentration index (CBCI), and metal accumulation index (MAI) were applied...
April 2017: Chemosphere
https://www.readbyqxmd.com/read/28089543/optimal-regulatory-circuit-topologies-for-fold-change-detection
#14
Miri Adler, Pablo Szekely, Avi Mayo, Uri Alon
Evolution repeatedly converges on only a few regulatory circuit designs that achieve a given function. This simplicity helps us understand biological networks. However, why so few circuits are rediscovered by evolution is unclear. We address this question for the case of fold-change detection (FCD): a response to relative changes of input rather than absolute changes. Two types of FCD circuits recur in biological systems-the incoherent feedforward and non-linear integral-feedback loops. We performed an analytical screen of all three-node circuits in a class comprising ∼500,000 topologies...
January 10, 2017: Cell Systems
https://www.readbyqxmd.com/read/28077627/a-feasibility-study-on-the-use-of-phantoms-with-statistical-lung-masses-for-determining-the-uncertainty-in-the-dose-absorbed-by-the-lung-from-broad-beams-of-incident-photons-and-neutrons
#15
Atiyeh Ebrahimi Khankook, Hashem Miri Hakimabad, Laleh Rafat Motavalli
Computational models of the human body have gradually become crucial in the evaluation of doses absorbed by organs. However, individuals may differ considerably in terms of organ size and shape. In this study, the authors sought to determine the energy-dependent standard deviations due to lung size of the dose absorbed by the lung during external photon and neutron beam exposures. One hundred lungs with different masses were prepared and located in an adult male International Commission on Radiological Protection (ICRP) reference phantom...
January 10, 2017: Journal of Radiation Research
https://www.readbyqxmd.com/read/28058236/the-iranian-version-of-the-copenhagen-psychosocial-questionnaire-copsoq-for-assessment-of-psychological-risk-factors-at-work
#16
Mohammad Aminian, Iman Dianat, Anvar Miri, Mohammad Asghari-Jafarabadi
Background: The Copenhagen Psychosocial Questionnaire (COPSOQ) is a widely used tool for evaluation of psychosocial risk factors at work. The aims of this study were to describe the short version of Farsi COPSOQ and to present its psychometric properties. Methods: A total of 427 administrative health care staff participated in this descriptive methodological study. Forward-backward procedure was adopted to translate the questionnaire from English into Farsi. Content validity was assessed by a panel of 10 experts...
2017: Health Promotion Perspectives
https://www.readbyqxmd.com/read/28047952/su-f-t-240-epid-based-quality-assurance-for-dosimetric-credentialing
#17
N Miri, J Lehmann, P Vial, P Greer
PURPOSE: We propose a novel dosimetric audit method for clinical trials using EPID measurements at each center and a standardized EPID to dose conversion algorithm. The aim of this work is to investigate the applicability of the EPID method to different linear accelerator, EPID and treatment planning system (TPS) combinations. METHODS: Combination of delivery and planning systems were three Varian linacs including one Pinnacle and two Eclipse TPS and, two ELEKTA linacs including one Pinnacle and one Monaco TPS...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047126/su-d-201-06-remote-dosmetric-auditing-of-vmat-deliveries-for-clinical-trials-using-epid
#18
K Legge, J Lehmann, P Vial, N Miri, P Greer
PURPOSE: To develop a method for remote dosimetric auditing the delivery of VMAT using EPID which allows for simple, inexpensive and time efficient dosimetric credentialing for clinical trials. METHODS: Remote centers are provided with CT datasets and planning guidelines to produce VMAT plans for a head and neck and a post-prostatectomy treatment. Plans are transferred in the planning system to two virtual water equivalent phantoms, one flat and one cylindrical...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046656/tu-fg-201-06-remote-dosimetric-auditing-for-clinical-trials-using-epid-dosimetry-a-pilot-study
#19
N Miri, J Lehmann, P Vial, K Legge, P Greer
PURPOSE: To perform a pilot study for remote dosimetric credentialing of intensity modulated radiation therapy (IMRT) based clinical trials. The study introduces a novel, time efficient and inexpensive dosimetry audit method for multi-center credentialing. The method employs electronic portal imaging device (EPID) to reconstruct delivered dose inside a virtual flat/cylindrical water phantom. METHODS: Five centers, including different accelerator types and treatment planning systems (TPS), were asked to download two CT data sets of a Head and Neck (H&N) and Postprostatectomy (P-P) patients to produce benchmark plans...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28028072/model-based-analysis-of-dna-replication-profiles-predicting-replication-fork-velocity-and-initiation-rate-by-profiling-free-cycling-cells
#20
Ariel Gispan, Miri Carmi, Naama Barkai
Eukaryotic cells initiate DNA synthesis by sequential firing of hundreds of origins. This ordered replication is described by replication profiles, which measure the DNA content within a cell population. Here, we show that replication dynamics can be deduced from replication profiles of free-cycling cells. While such profiles lack explicit temporal information, they are sensitive to fork velocity and initiation capacity through the passive replication pattern, namely the replication of origins by forks emanating elsewhere...
February 2017: Genome Research
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