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Ali Farmani, Mahdi Yavarian, Abbas Alighanbari, Mehdi Miri, Mohammad H Sheikhi
A tunable graphene plasmonic Y-branch switch at THz wavelengths is proposed. The effects of magnetic and electric biasing are studied to harness the transmission of the transverse electric and magnetic guided mode resonances. In the structure, hexagonal boron nitride is utilized as a substrate for graphene. The application of hexagonal boron nitride, with the advantages of high mobility and ultralow ohmic loss, introduces a promising alternative substrate for graphene. Analytical and numerical results show that, by slight variation of the doping level in graphene through magnetic and electric biasing, the characteristics of the propagation of the guided mode resonances can be manipulated...
November 10, 2017: Applied Optics
Yanyan Li, Yin Xiang, Song Zhang, Yan Wang, Jie Yang, Wei Liu, Fengtai Xue
The aim of this study is to explore the role of thioredoxin-2 (Trx2) in autophagy and apoptosis during myocardial ischemia-reperfusion (I/R) injury in vivo. In the study, adult male Sprague-Dawley rats were assigned to four groups at random and pretreated with normal saline (sham operation and I/R groups) and either a control lentivirus (Lv-GFP-N) or one expressing Trx2 (Lv-GFP-Trx2). Sevendays after pretreatment, rat MIRI models were produced via occlusion of the left anterior descending coronary artery for 30 min followed by reperfusion for 6 h...
2017: American Journal of Translational Research
Miri Hyun, Chang In Noh, Seong Yeol Ryu, Hyun Ah Kim
Background/Aims: Klebsiella pneumoniae is second most common organism of gram-negative bacteremia in Korea and one of the most common cause of urinary tract infection, and intra-abdominal infection. Methods: We compared clinical and microbiological characteristics about K. pneumoniae bacteremia in a tertiary hospital between 10 years. Group A is who had K. pneumoniae bacteremia at least one time from January 2004 to December 2005. Group B is from January 2012 to December 2013...
November 10, 2017: Korean Journal of Internal Medicine
Aida Iraji, Omidreza Firuzi, Mehdi Khoshneviszadeh, Marjan Tavakkoli, Mohammad Mahdavi, Hamid Nadri, Najmeh Edraki, Ramin Miri
Alzheimer's disease (AD) is a neurodegenerative disorder known for the presence of amyloid beta plaques resulting from the sequential action of β-secretase and γ-secretase on amyloid precursor protein. We developed and synthesized, through click reactions, a new family of iminochromene carboxamides containing different aminomethylene triazole. The BACE1 inhibition, neuroprotective capacity and metal chelation of these derivatives make them ideal candidates against AD. Most of the synthesized compounds were shown to have potent BACE1 inhibitory activity in a FRET assay, with an IC50 value of 2...
December 1, 2017: European Journal of Medicinal Chemistry
Yu Ri Woo, Jong Sic Kim, Ji Hong Lim, Sewon Hwang, Miri Kim, Jung Min Bae, Young Min Park, Chang-Ki Min, Dong-Wook Kim, Hyun Jeong Park
BACKGROUND: Multiple myeloma (MM) is a plasma cell dyscrasia characterized by the presence of a clonal proliferation of tumor cells. Cutaneous involvement of MM is very rare and remains poorly understood. OBJECTIVE: The aim of this study was to examine the clinical and histopathologic characteristics of cutaneous involvement in MM and identify factors associated with overall survival of MM with cutaneous involvement. METHODS: The medical records of 1228 patients with MM were retrieved and analyzed...
October 26, 2017: Journal of the American Academy of Dermatology
Yan Xiao, Liang Ding, Yi-Huang Gu
Myocardial cell apoptosis is very common in the clinic, and is caused by myocardial ischemia reperfusion injury (MIRI). There are different degrees of cell apoptosis in MIRI. However, initiation of the signal transduction mechanism of myocardial cell apoptosis is unclear. The present research confirmed that acupuncture and moxibustion are effective interventions for cell apoptosis in MIRI through three approaches:the death receptor pathway, mitochondrial pathway and endoplasmic reticulum pathway. In this paper, the authors summarize the mechanism characteristics of acupuncture and moxibustion in MIRI cell apoptosis, and discuss the signal transduction pathways involved in the effects of acupuncture and moxibustion in MIRI cell apoptosis, in order to provide new ideas and evidence for the clinical application of acupuncture and moxibustion to prevent cell apoptosis in MIRI...
October 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
Tao Zhou, Shanliang Guo, Shaolin Wang, Qiong Li, Mingsheng Zhang
This study was designed to investigate possible protective effects of sevoflurane on myocardial ischemia-reperfusion injury (MIRI) and its impact on expression of HIF-1α and caspase-3 in rats, so as to provide new insights for the treatment of MIRI. Forty SD rats were randomly divided into four groups (n=10) including Sham operation (Sham), ischemia-reperfusion (IR), sevoflurane preconditioning group (Sevo-Pre) and sevoflurane post-conditioning (Sevo-Post) groups. Perfusion was performed using ex vivo heart perfusion...
November 2017: Experimental and Therapeutic Medicine
Mitra Kiani Nasab, Laleh Rafat Motavalli, Hashem Miri Hakimabad
In this paper, the dose assessment for the iodine inhalation exposure in 19 aerosol sizes and three gas/vapor forms at three levels of thyroid uptake, was performed. Two different modes of work (light vs. heavy) and breathing (nose vs. mouth) for aerosol inhalation were investigated. In order to calculate the cumulated activities per unit of inhaled activity, a combined model which included the latest models of both human respiratory and alimentary tract was developed. The S values for (131)I were computed based on the ICRP adult male and female reference voxel phantoms by the Monte Carlo method...
November 1, 2017: Journal of Environmental Radioactivity
Inbar Levkovich, Miri Cohen, Khaled Karkabi
The study explored the experience of fatigue, its effects and ways of coping with fatigue and the role of family and social support among breast cancer patients. In-depth, semi-structured interviews were conducted with 13 breast cancer patients stages I-III, aged 34-67, who were up to one year after the termination of chemotherapy. Two main themes emerged: "Being imprisoned in the body of an 80-year-old", focuses the fatigue experienced by younger and older women, during and post treatment, including the different patterns of fatigue and the various means of coping with fatigue; The "Family's bear-hug" exemplifies the role of the environment in coping with the experience of fatigue and the complexities entailed in receiving support from family and friends...
November 2, 2017: Behavioral Medicine
Fei He, Qianfu Wu, Banglong Xu, Xiaocheng Wang, Jixiong Wu, Li Huang, Jing Cheng
Objective: Previous studies have demonstrated STIM1-mediated store-operated Ca(2+) entry(SOCE) contributes to intracellular Ca(2+) accumulation. The present study aimed to investigate the expression of STIM1 and Orai1/TRPC1 in the context of myocardial ischemia/reperfusion injury(MIRI) and the effect of STIM1 inhibition on Ca(2+) accumulation and apoptosis in H9c2 cardiomyocytes subjected to hypoxia/reoxygenation(H/R). Methods: Expression of STIM1/Orai1/TRPC1 was determined by RT-PCR and Western Blot in mice subjected to MIRI and H9C2 cardiomyocytes subjected to H/R...
October 31, 2017: Bioscience Reports
Cheng-Fu Tan, Jie Yan, Chao Wang, Xiao-Rong Chang, Wen-Juan Xie, Jing-Jing Yang, Mi Liu, Hai-Bo Lin, Xiang-Chang He
OBJECTIVE: To observe the effect of electroacupuncture (EA) and moxibustion (Moxi) pretreatment on expression of myocardial heat shock protein (HSP) in acute myocardial ischemia-reperfusion injury (MIRI) rabbits. METHODS: A total of 72 New Zealand rabbits were randomly divided into 4 groups:sham operation, MIRI model, EA pretreatment and Moxi pretreatment (n=18 rabbits in each group) which were further divided into 0, 24 and 48 h (time-point) subgroups (n=6 in each)...
February 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
Mohammad Miri, Elham Akbari, Abdeltif Amrane, Seyed Javad Jafari, Hadi Eslami, Edris Hoseinzadeh, Mansur Zarrabi, Javad Salimi, Mohsen Sayyad-Arbabi, Mahmoud Taghavi
The heavy metal (Pb, Cd, Cr, and Ni) content of a fish species consumed by the Sistan population and its associated health risk factors were investigated. The mean concentrations of Pb, Cd, and Cr were slightly higher than the standard levels. The Ni content of fish was below the maximum guideline proposed by the US Food and Drug Administration (USFDA). The average estimated weekly intake was significantly below the provisional tolerable intake based on the FAO and WHO standards for all studied metals. The target hazard quotients (THQ) of all metals were below 1, showing an absence of health hazard for the population of Sistan...
October 25, 2017: Environmental Monitoring and Assessment
Takeshi Kusunoki, Hirotomo Homma, Yoshinobu Kidokoro, Aya Yanai, Satoshi Hara, Yuko Kobayashi, Miri To, Ryo Wada, Katsuhisa Ikeda
No abstract text is available yet for this article.
September 15, 2017: Clinics and Practice
Ken Sato, Hiroyuki Kuroda, Michiko Yamada, Saki Ameda, Shogo Miura, Hiroya Sakano, Takanori Shibata, Naoki Uemura, Tomoyuki Abe, Shigeyuki Fujii, Masahiro Maeda, Miri Fujita, Masayoshi Kobune, Junji Kato
A 75-year-old man was admitted to our hospital in May 2016 with progressive shortness of breath. We considered him to be experiencing acute heart failure caused by atrial fibrillation. Contrast-enhanced computed tomography showed a hypodense mass involving the right atrium and left ventricle, pericardial effusion, and lymphadenopathy of the groin. Histological finding from the groin and pericardial effusion analysis showed diffuse large B-cell lymphoma(DLBCL). We thus diagnosed this patient with cardiac tamponade owing to the involvement of the heart by DLBCL...
October 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Miri Danan-Gotthold, Erez Y Levanon
Concentration is important and not only while driving; a new study indicates how an adjacent genomic element helps to increase the efficiency of a specific adenosine to inosine RNA editing reaction, by providing a means to increase the local concentration of the RNA editing enzyme ADAR.
October 23, 2017: Genome Biology
Zeinab Jafari, Abbas Zarifkar, Mehdi Miri
Regarding the importance of bandwidth and capacity expansion in communication systems, a novel mode division (de)multiplexer based on subwavelength grating (SWG) is proposed. SWG-based devices could have smaller sizes, be much more fabrication-tolerant, and have much wider bandwidths due to the reduced confinement of the field and dispersion. It is also feasible to reduce the loss of a SWG-based device by tuning the duty cycle of the grating. Owing to these properties of SWGs, we have designed a compact fabrication-tolerant two-mode division (de)multiplexer...
September 10, 2017: Applied Optics
Shani Dahan, Yahel Segal, Abdulla Watad, Shir Azrielant, Asaf Shemer, Dror Maymon, Yuri I Stroev, Polina A Sobolevskaya, Elena A Korneva, Miri Blank, Boris Bilburd, Ora Shovman, Howard Amital, Michael Ehrenfeld, Amir Tanay, Shay Kivity, Elon Pras, Joav Chapman, Jan Damoiseaux, Ricard Cervera, Chaim Putterman, Iziaslav Shapiro, Luc Mouthon, Roberto Periconne, Nicola Bizzaro, Omry Koren, Gabriela Riemekasten, Valeriy A Chereshnev, Vadim I Mazurov, Mark Goloviznin, Victor Gurevich, Leonid P Churilov, Yehuda Shoenfeld
No abstract text is available yet for this article.
October 13, 2017: Autoimmunity Reviews
Marjan Mahjour, Arash Khoushabi, Maryam Miri Ghale Novi, Zohre Feyzabadi
Kidneys have an important role in the body. Any damage to kidney role can damage many organs of the body. Traditional Persian Medicine (TPM) or Iranian traditional medicine (ITM) is an ancient temperamental medicine with many literatures about kidney diseases and Avicenna (980-1025 AD) describes kidney diseases in details. This is a review study by searching of the most important clinical and pharmaceutical TPM textbooks such as The Canon of Medicine by Avicenna and scientific data banks using keywords such as "Hozal-e-Kolye", renal atrophy, tubular atrophy, kidney, chronic kidney disease, and end stage renal disease...
October 2017: Journal of Traditional and Complementary Medicine
Miri Zilka, Simone Sturniolo, Steven P Brown, Jonathan R Yates
In this article, we introduce and apply a methodology, based on density functional theory and the gauge-including projector augmented wave approach, to explore the effects of packing interactions on solid-state nuclear magnetic resonance (NMR) parameters. A visual map derived from a so-termed "magnetic shielding contribution field" can be made of the contributions to the magnetic shielding of a specific site-partitioning the chemical shift to specific interactions. The relation to the established approaches of examining the molecule to crystal change in the chemical shift and the nuclear independent chemical shift is established...
October 14, 2017: Journal of Chemical Physics
Xiao-Lei Zhang, Jennifer L McGlothan, Omid Miry, Kirstie H Stansfield, Meredith K Loth, Patric K Stanton, Tomás R Guilarte
Childhood lead (Pb2+) intoxication is a public health problem of global proportion. Lead exposure during development produces multiple effects on the central nervous system including impaired synapse formation, altered synaptic plasticity, and learning deficits.In primary hippocampal neurons in culture and hippocampal slices, Pb2+ exposure inhibits vesicular release and reduces the number of fast-releasing sites, an effect associated with Pb2+ inhibition of NMDA receptor-mediated trans-synaptic Brain-Derived Neurotrophic Factor (BDNF) signaling...
October 4, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
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