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Miri Kim, Eun Young Sun, Haw Young Jung, Baik Kee Cho, Hyun Jeong Park
No abstract text is available yet for this article.
October 2016: Annals of Dermatology
Shasha Liu, Qidi Ai, Kai Feng, Yubing Li, Xiang Liu
Reperfusion therapy is widely used to treat acute myocardial infarction (AMI). However, further injury to the heart induced by rapidly initiating reperfusion is often encountered in clinical practice. A lack of pharmacological strategies in clinics limits the prognosis of patients with myocardial ischemia-reperfusion injury (MIRI). Dihydromyricetin (DMY) is one of the most abundant components in vine tea, commonly known as the tender stems and leaves of Ampelopsis grossedentata. The aim of this study was to evaluate the cardioprotection of DMY against myocardial ischemia-reperfusion (I/R) injury and to further investigate the underlying mechanism...
October 13, 2016: Apoptosis: An International Journal on Programmed Cell Death
Yu Shrike Zhang, Farideh Davoudi, Philipp Walch, Amir Manbachi, Xuan Luo, Valeria Dell'Erba, Amir K Miri, Hassan Albadawi, Andrea Arneri, Xiaoyun Li, Xiaoying Wang, Mehmet Remzi Dokmeci, Ali Khademhosseini, Rahmi Oklu
Pathologic thrombosis kills more people than cancer and trauma combined; it is associated with significant disability and morbidity, and represents a major healthcare burden. Despite advancements in medical therapies and imaging, there is often incomplete resolution of the thrombus. The residual thrombus can undergo fibrotic changes over time through infiltration of fibroblasts from the surrounding tissues and eventually transform into a permanent clot often associated with post-thrombotic syndrome. In order to understand the importance of cellular interactions and the impact of potential therapeutics to treat thrombosis, an in vitro platform using human cells and blood components would be beneficial...
October 18, 2016: Lab on a Chip
Yana Davidov, Bella Ungar, Haggai Bar Yoseph, Dan Carter, Ola Haj-Natour, Miri Yavzori, Yehuda Chowers, Rami Eliakim, Shomron BenHorin, Uri Kopylov
BACKGROUND: The association of infliximab (IFX) trough levels with clinical and endoscopic outcomes in inflammatory bowel disease is well established. However there is scarce data regarding the association of perianal fistula response with IFX. The aim of the study was to establish whether early induction infliximab levels and anti-infliximab antibodies (ATI) are associated with perianal fistula response. METHODS: Consecutive CD patients with perianal fistulae that were treated with IFX between 2008 and 2016 were included in the study...
October 4, 2016: Journal of Crohn's & Colitis
Samira Yadegari, Askar Ghorbani, S Roohollah Miri, Mohammad Abdollahi, Mohsen Rostami
INTRODUCTION: Despite increasing the use of magnetic resonance imaging (MRI), cerebral venous sinus thrombosis (CVST) has remained an under-diagnosed condition. In this study, characteristics and frequency of various risk factors of CVST patients in a tertiary referral hospital were closely assessed. METHODS: Patients with an unequivocal diagnosis of CVST confirmed by MRI and magnetic resonance venography during 6 years of the study were included. All data from the onset of symptoms regarding clinical signs and symptoms, hospital admission, seasonal distribution, medical and drug history, thrombophilic profile, D-dimer, neuroimaging, cerebrospinal fluid findings, mortality, and outcome were collected and closely analyzed...
October 2016: Journal of Neurosciences in Rural Practice
Feyza Alyu, Miriş Dikmen
OBJECTIVE: Epilepsy is a chronic neurological disease characterised with seizures. The aetiology of the most generalised epilepsies cannot be explicitly determined and the seizures are pronounced to be genetically determined by disturbances of receptors in central nervous system. Besides, neurotransmitter distributions or other metabolic problems are supposed to involve in epileptogenesis. Lack of adequate data about pharmacological agents that have antiepileptogenic effects point to need of research on this field...
October 3, 2016: Acta Neuropsychiatrica
Zhaoyang Zhang, Yiqi Zhang, Jiteng Sheng, Liu Yang, Mohammad-Ali Miri, Demetrios N Christodoulides, Bing He, Yanpeng Zhang, Min Xiao
We experimentally demonstrate PT-symmetric optical lattices with periodical gain and loss profiles in a coherently prepared four-level N-type atomic system. By appropriately tuning the pertinent atomic parameters, the onset of PT-symmetry breaking is observed through measuring an abrupt phase-shift jump between adjacent gain and loss waveguides. The experimental realization of such a readily reconfigurable and effectively controllable PT-symmetric waveguide array structure sets a new stage for further exploiting and better understanding the peculiar physical properties of these non-Hermitian systems in atomic settings...
September 16, 2016: Physical Review Letters
Zahra Moudi, Ebrahim Miri-Moghaddam
In the present study, an embedded design was applied in order to conduct a one-year cross-sectional audit of chorionic villus sampling (CVS) and foetal outcomes affected by β-thalassemia major (β-TM) in a prenatal diagnosis (PND) setting. In addition, we explored the decisions regarding pregnancy termination among women whose pregnancy (or child) was affected by β-TM. In the quantitative phase, the available data in the clients' medical records were analysed, while the qualitative phase was performed using a grounded theory method...
September 28, 2016: Journal of Genetic Counseling
Bassam Krifa, Leila Ghidaoui, Emna Bahlouli, Ines Loubiri, Mariem Rekik, Imen Miri, Fatma Ezzahra Ben Salah, Catherine Dziri
No abstract text is available yet for this article.
September 2016: Annals of Physical and Rehabilitation Medicine
Mariem Rekik, Khaoula Achour, Anouer Abdallah, Sonia Lebib, Imen Miri, Fatima Zahra Ben Salah, Catherine Dziri
OBJECTIVE: The aim of our study was to assess the bladder and sphincter function after brain injury (BI) and to review their association with quality of life (QOL). MATERIAL/PATIENTS AND METHODS: We conducted a cross-sectional study, including patients referred to physical and rehabilitation medicine department at the Med Kassab Institute of Orthopedics. The initial gravity data were collected. The bladder-sphincter assessment included evaluation of the urine drain mode, the irritative disorders, obstructive disorders, disorders of transit and the existence of secondary anal lesions...
September 2016: Annals of Physical and Rehabilitation Medicine
Mariem Rekik, Emna Bahlouli, Bessem Krifa, Sonia Lebib, Imen Miri, Fatima Zahra Ben Salah, Catherine Dziri
OBJECTIVE: The aim of our study was to assess the functional outcome of brain injury (BI) victims and to review the impact of treatment time on functional abilities. MATERIAL/PATIENTS AND METHODS: We conducted a cross-sectional study including patients referred to physical and rehabilitation medicine department at the Med Kassab Institute of Orthopedics. The initial gravity data were collected. The functional outcome was assessed by the Glasgow Outcome Scale (GOS) French version, the get up and go test, the walk test on 10m, the functional independence measure (FIM) and daily life activities...
September 2016: Annals of Physical and Rehabilitation Medicine
Katayoun Javidnia, Ehsan Faghih-Mirzaei, Ramin Miri, Mahshid Attarroshan, Kamiar Zomorodian
2,3-Butanediol (2,3-BD) is a valuable bulk chemical owing to its extensive application in chemical and pharmaceutical industry with diverse applications in drug, cosmetics and food products. In the present study, the biotransformation of acetoin to 2,3-BD by five plant species (Brassica oleracea, Brassica rapa, Daucuscarota, Pastinaca sativa, and Raphnussativus) and five microorganisms (Aspergillusfoetidus, Penicillumcitrinum, Saccharomyces carlbergensis, Pichiafermentans, and Rhodotrulaglutinis) was investigated as a method for the production of 2,3-BD, which can serve as an alternative to the common pentoses and hexoses fermentation by microorganisms...
July 2016: Research in Pharmaceutical Sciences
Mohammad Rohani, Shahnaz Miri, Alireza Rezai-Ashtiani
No abstract text is available yet for this article.
July 6, 2016: Iranian Journal of Neurology
H El Miri, C Faraj, O Himmi, A Hmamouch, S Maniar, T Laaroussi, M Rhajaoui, F Sebti, A Benhoussa
Cutaneous leishmaniasis (CL) is a major public health problem in Morocco. Three distinct parasites are involved; Leishmania tropica, Leishmania major and Leishmania infantum. The objective of this study is to investigate the epidemiological and the clinical features of endemic foci of CL in Sidi Kacem and Ouazzane provinces in the north of Morocco including molecular identification of parasites. We studied the evolution and the distribution of 1,656 CL cases coming from 39 sectors in these provinces between 1997 and 2012...
September 19, 2016: Bulletin de la Société de Pathologie Exotique
Qiang Li, Li Shen, Zhen Wang, Hai-Peng Jiang, Li-Xia Liu
OBJECTIVE: To determine the mechanism by which Tanshinone IIA (Tan IIA) relieves myocardial ischemia reperfusion injury (MIRI) in rats via the PI3K/Akt/mTOR signaling pathway. METHODS: Sprague-Dawley (SD) rats received an intravenous injection of Tan IIA and LY294002 and were divided into the sham, control (myocardial ischemia reperfusion), Tan-L (low-dose Tan IIA), Tan-H (high-dose Tan IIA), Tan-L+LY (low-dose Tan IIA+LY294002), Tan-H+LY (high-dose Tan IIA+LY294002) and LY (LY294002) groups...
September 16, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Mohammad Haji Aghajani, Monireh Ghazaeian, Hamid Reza Mehrazin, Mohammad Sistanizad, Mirmohammad Miri
Medication errors are one of the important factors that increase fatal injuries to the patients and burden significant economic costs to the health care. An appropriate medical history could reduce errors related to omission of the previous drugs at the time of hospitalization. The aim of this study, as first one in Iran, was evaluating the discrepancies between medication histories obtained by pharmacists and physicians/nurses and first order of physician. From September 2012 until March 2013, patients admitted to the post CCU of a 550 bed university hospital, were recruited in the study...
2016: Iranian Journal of Pharmaceutical Research: IJPR
Najmeh Edraki, Umashankar Das, Bahram Hemateenejad, Jonathan R Dimmock, Ramin Miri
1-[4-(2-Alkylaminoethoxy) phenylcarbonyl]-3,5-bis(arylidene)-4-piperidones are a novel class of potent cytotoxic agents. These compounds demonstrate low micromolar to submicromolar IC50 values against human Molt 4/C8 and CEM T-lymphocytes and murine leukemia L1210 cells. In this study, a comparative QSAR investigation was performed on a series of 3,5-bis (arylidene)-4-piperidones using different chemometric tools to develop the best predictive models for further development of analogs with improved cytotoxicity...
2016: Iranian Journal of Pharmaceutical Research: IJPR
Yufen Li, Xiaomei Wang, Changli Lou
BACKGROUND Calcium overload, inflammation, and apoptosis play important roles in myocardial ischemia-reperfusion injury (MIRI). Gastrodin pretreatment can alleviate MIRI. This study observed sarcoplasmic reticulum calcium transport ATPase (Ca2+-ATPase, SERCA) and calcium phosphate (PLB) protein expression in the ventricular remodeling process after myocardial infarction to explore the effect of gastrodin pretreatment on MIRI. MATERIAL AND METHODS Healthy 7-week-old male SD rats were randomly divided into a sham group (A), a model group (B), and gastrodin pretreatment groups C, D, and E (100, 200, and 400 mg/kg, respectively) with 20 in each group...
September 19, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Yusuke Sugama, Hiroyuki Kuroda, Hiroto Horiguchi, Natsumi Yamauchi, Ken Sato, Michiko Yamada, Kohta Hamaguchi, Hajime Nakamura, Tomoyuki Abe, Shigeyuki Fujii, Masahiro Maeda, Miri Fujita, Masato Koguma, Tetsuhiko Koguma, Junji Kato
An 80-year-old man received a diagnosis of anemia and a decreased platelet count from his physician in 2008, and was referred to our department where primary myelofibrosis was diagnosed.The patient was classified into the lower risk group according to the International Prognostic Scoring System(IPSS), and was followed up without treatment.In June 2010, pancytopenia progressed, and the patient was reclassified into the higher risk group.Blood count did not increase with metenolone treatment, but increased with zoledronic acid(ZA)that he started receiving from January 2012...
September 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
MirFaez Miri, Zahra Etesami
We study a nanoscale machine composed of a rack and a pinion with no contact, but intermeshed via the lateral Casimir force. We adopt a simple model for the random velocity of the rack subject to external random forces, namely, a dichotomous noise with zero mean value. We show that the pinion, even when it experiences random thermal torque, can do work against a load. The device thus converts the kinetic energy of the random motions of the rack into useful work.
August 2016: Physical Review. E
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