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https://www.readbyqxmd.com/read/29332659/a-case-of-hepatic-tuberculosis-a-tuberculoma
#1
Sameer Khanijo, Pragati Tandon
Tuberculosis (TB) is a common cause of morbidity and mortality worldwide and its eradication in the United States has stalled for the first time in decades. Isolated hepatic TB is an extremely uncommon form of extrapulmonary TB. Here we present a case of a tuberculous liver abscess and suggest that TB should be considered in patients who fail to respond to antibiotics and prompt diagnostic intervention.
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332657/primary-oral-tuberculosis-on-the-tongue-mimicking-squamous-cell-carcinoma
#2
Karandeep Singh Arora, Sunny Garg, Prabhpreet Kaur, Shreeyam Mohapatra
Tuberculosis is chronic granulomatous disease with rare oral manifestations. But if so are overlooked by most of the health care professionals. Clinically, most of the times, a tuberculous ulcer may mimic an ulcer of malignant origin and may be misdiagnosed. So, keeping in mind the etiology and the nature of the ulcer, it should be differentially diagnosed and a histopathological examination should only confirm the final diagnosis of the ulcer.
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332650/amplification-of-hsp-65-gene-and-usage-of-restriction-endonuclease-for-identification-of-non-tuberculous-rapid-grower-mycobacterium
#3
Ajoy Kumar Verma, Rohit Sarin, Vijay Kumar Arora, Gavish Kumar, Jyoti Arora, Paras Singh, Vithal Prasad Myneedu
BACKGROUND: The rapid grower mycobacteria have emerged as significant group of human pathogen amongst the Runyon group IV organisms that are capable of causing infection in both the healthy and immunocompromised hosts. Study aimed to identification of species amongst rapid grower non tuberculous mycobacterial isolates by polymerase chain reaction - restriction enzyme analysis (PRA). Analysis and comparison of results with standard biochemical tests. METHODS: Rapid grower non tuberculous mycobacteria had been collected from liquid culture section during the study period...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332649/isoniazid-and-rifampicin-heteroresistant-mycobacterium-tuberculosis-isolated-from-tuberculous-meningitis-patients-in-india
#4
Renu Gupta, Rajeev Thakur, Suman Kushwaha, Nupur Jalan, Pumanshi Rawat, Piyush Gupta, Amitesh Aggarwal, Meena Gupta, Vikas Manchanda
BACKGROUND: Heteroresistant Mycobacterium tuberculosis (mixture of susceptible and resistant subpopulations) is thought to be a preliminary stage to full resistance and timely detection, initiation of correct treatment is vital for successful anti tubercular therapy. The aim of this study was to detect multi drug resistant (MDR) and heteroresistant M. tuberculosis with the associated gene mutations from patients of tuberculous meningitis. METHODS: A total of 197 M...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29332619/clinical-characteristics-of-non-tuberculous-mycobacterial-pulmonary-infections-in-bamako-mali
#5
B Kone, Y S Sarro, M Maiga, M Sanogo, A M Somboro, B Diarra, A C G Togo, N Coulibaly, B P P Dembele, D Goita, B Baya, A Kone, S Diabaté, M A Polis, M Belson, S Dao, S Orsega, C J Achenbach, R L Murphy, S Diallo, S Siddiqui
The global spread of non-tuberculous mycobacteria (NTM) may be due to HIV/AIDS and other environmental factors. The symptoms of NTM and tuberculosis (TB) disease are indistinguishable, but their treatments are different. Lack of research on the epidemiology of NTM infections has led to underestimation of its prevalence within TB endemic countries. This study was designed to determine the prevalence and clinical characteristics of pulmonary NTM in Bamako. A cross-sectional study which include 439 suspected cases of pulmonary TB...
January 15, 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29331660/persistent-contamination-of-heater-cooler-units-for-extracorporal-circulation-cured-by-chlorhexidine-alcohol-in-water-tanks
#6
Sara Romano-Bertrand, Marine Evrevin, Chloé Dupont, Jean-Marc Frapier, Jean-Claude Sinquet, Elodie Bousquet, Bernard Albat, Estelle Jumas-Bilak
Recently, surgical site infections due to non-tuberculous Mycobacterium (NTM) have been linked to heater-cooler units (HCUs) contamination. ECDC and manufacturers now recommend the use of hydrogen peroxide in filtered water to fill HCU tanks. After implementation of these measures in our hospital, HCUs became heavily contaminated by opportunistic waterborne pathogens such as Pseudomonas aeruginosa and Stenotrophomonas maltophilia. No NTM were detected but fast-growing resistant bacteria could impair their detection...
January 10, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29330673/vacuum-assisted-closure-therapy-of-paradoxical-reaction-in-tuberculous-lymphadenopathy-caused-by-mycobacterium-africanum
#7
H F Geerdes-Fenge, P Pongratz, J Liese, E C Reisinger
A 26-year-old HIV-negative male from Ghana was treated for cervical, intrathoracic and abdominal lymph node tuberculosis (TB) and tuberculous hepatitis. Penetration of the thoracic trachea by a mediastinal lymph node had caused bronchomucosal TB. Sputum culture grew M. africanum, sensitive to all first-line antituberculous drugs. Four weeks after the beginning of directly observed treatment with isoniazid, rifampin, pyrazinamide and ethambutol, the right cervical lymph node increased in size, liquefied and caused a spontaneous fistula...
January 12, 2018: Infection
https://www.readbyqxmd.com/read/29330276/cutaneous-mycobacterium-massiliense-infection-from-tattooing-a-common-yet-under-reported-and-persistent-epidemic-hazard-for-dermatologists
#8
Lymaries Velez, Jennifer Harb, Stephanie Anuszewski, Stanton Wesson
Tattoo popularity continues to rise, with 3 in 10 Americans bearing at least one. Among tattoo complications, non-tuberculous mycobacteria (NTM) has emerged as a global public health concern. NTM infections associated with tattooing of immunocompetent individuals have occurred as sporadic cases and community outbreaks. Water sources are considered the major pathogenic reservoirs. Tattoo-related inoculation has been linked to contamination of ink, either during the manufacturing process or during dilution of black ink using non-sterile water...
January 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29327521/cerebrospinal-fluid-a-clinicopathologic-analysis
#9
Asha Shenoy, Heena Desai, Aparna Mandvekar
Context and Objective: This study aims to emphasize the importance of an appropriate CSF examination in patients of suspected CNS disease and the necessity of correlating it with the clinico-radiologic findings which will help in early diagnosis of CNS diseases and guide the further management of the disease. Design: In this 2 year study, 215 CSF samples from patients with clinically suspected diseases of the CNS were studied. The CSF samples were analyzed for gross examination, protein, sugar, adenosine deaminase (ADA) levels, microscopic examination and microbiologic examination...
December 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29326867/cavitary-lung-lesion-suspicious-for-malignancy-reveals-mycobacterium-xenopi
#10
Sumit Fogla, Vaishali M Pansare, Luis G Camero, Uzma Syeda, Naveen Patil, Arun Chaudhury
We report the case of a 68-year-old gentleman who presented with musculoskeletal chest pain which appeared suddenly when he bent over with his dog. The chest pain was localized to the left lower chest and increased with movement and deep breathing. The patient did not complain weight loss, night sweat, fever or chill. He complained of mild cough, with expectoration of whitish mucus. Imaging revealed cavitary chest lesion in the right upper lobe, which was initially suspected to be lung cancer. The patient had a 50-year-old history of smoking 2 packs per day...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29326000/epidemiology-of-tuberculosis-in-spain-results-obtained-by-the-national-epidemiological-surveillance-network-in-2015
#11
Rosa Cano-Portero, Rocío Amillategui-Dos Santos, Raquel Boix-Martínez, Amparo Larrauri-Cámara
The epidemiological surveillance data for tuberculosis in Spain in 2015 is analysed in this report. This information was gathered through cases reported to the Red Nacional de Vigilancia Epidemiológica [National Epidemiological Surveillance Network]. In addition, the update of the treatment of the cases reported in 2014 is included. The incidence rate of tuberculosis in 2015 was 10.59 cases per 100,000 inhabitants, 10% less than in 2014. This decrease was mainly due to the sustained decreased trend of pulmonary tuberculosis rates, from other locations and in adults, while for cases of tuberculous meningitis and in children the decrease is less marked, with a tendency to stabilization...
January 8, 2018: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29325063/epidemiology-and-outcomes-of-hematopoietic-stem-cell-transplant-in-hiv-patients-from-1998-to-2012-a-nationwide-analysis
#12
Kathan Mehta, Annie Im, Farah Rahman, Hong Wang, Peter Veldkamp
Background: Prior studies have shown that outcomes of hematopoietic stem cell transplantation (HSCT) in HIV (+) patients are similar to HIV (-) patients since effective implementation of HAART by 1998; but they are limited by small sample size or non-inclusion of recent data. Methods: We queried National Inpatient Sample, a large inpatient dataset in the US, from 1998 to 2012 for HSCT using ICD9 procedure code 41.0. HIV patients were identified by ICD9 diagnostic code of 042, 043, 044, V08 and 079...
January 6, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29322464/transcriptional-profiling-mycobacterium-tuberculosis-from-patient-sputa
#13
Leticia Muraro Wildner, Katherine A Gould, Simon J Waddell
The emergence of drug resistance threatens to destroy tuberculosis control programs worldwide, with resistance to all first-line drugs and most second-line drugs detected. Drug tolerance (or phenotypic drug resistance) is also likely to be clinically relevant over the 6-month long standard treatment for drug-sensitive tuberculosis. Transcriptional profiling the response of Mycobacterium tuberculosis to antimicrobial drugs offers a novel interpretation of drug efficacy and mycobacterial drug-susceptibility that likely varies in dynamic microenvironments, such as the lung...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29321098/spondylodiscitis-diagnosis-and-treatment-options
#14
Christian Herren, Norma Jung, Miguel Pishnamaz, Marianne Breuninger, Jan Siewe, Rolf Sobottke
BACKGROUND: A recent population-based study from Denmark showed that the incidence of spondylodiscitis rose from 2.2 to 5.8 per 100 000 persons per year over the period 1995-2008; the age-standardized incidence in Germany has been estimated at 30 per 250 000 per year on the basis of data from the Federal Statistical Office (2015). The early diagnosis and treatment of this condition are essential to give the patient the best chance of a good outcome, but these are often delayed because it tends to present with nonspecific manifestations, and fever is often absent...
December 25, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29318438/presumed-tuberculous-uveitis-in-a-university-based-tertiary-referral-center-in-saudi-arabia
#15
Awad Al-Qarni, Marwan A Abouammoh, Abdullah N Almousa, Ahmed Mousa, Ahmed M Abu El-Asrar
PURPOSE: To describe clinical characteristics and outcomes of treatment in patients with presumed tuberculous uveitis (PTU). METHODS: All patients diagnosed with PTU between January 1996 and March 2013 were reviewed. The diagnosis was made when clinical findings were consistent with possible intraocular tuberculosis, strongly positive purified protein derivative (PPD) skin test result, and response to anti-tuberculous therapy with no other cause of uveitis as suggested by history, symptoms, or ancillary testing...
January 9, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29310592/characterization-of-non-tuberculous-mycobacterium-from-humans-and-water-in-an-agropastoral-area-in-zambia
#16
Ngula Monde, Musso Munyeme, Adrian Muwonge, John Bwalya Muma, Sydney Malama
BACKGROUND: The non-tuberculous mycobacteria include those mycobacterium species that are not members of the Mycobacterium tuberculosis complex, the causative agent of pulmonary tuberculosis and Mycobacterium leprae. In Zambia, Non-tuberculous Mycobacteria are gaining recognition as pathogens of public health significance. However, there is scanty information on the isolation and speciation of these organisms for better patient management, consequently reducing the burden of these infections...
January 8, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29307027/does-restricted-diffusion-in-the-splenium-indicate-an-acute-infarct
#17
Zeynep Ezgi Balcik, Songül Senadim, Aslı Keskek, Ayşe Ozudogru, Ayhan Koksal, Aysun Soysal, Dilek Atakli
OBJECTIVE: Although splenial lesions are rare, they are frequently associated with ischemic infarcts, antiepileptic drug toxicity or abrupt discontinuation, viral encephalitis, and metabolic disturbances. In this study, we evaluated clinical and imaging findings and aetiology in 16 patients with splenium lesions. METHODS: Between 2013 and 2017, patients with splenium lesions were examined. Magnetic resonance imaging (MRI) was performed using a 1.5-T unit with fluid attenuation inversion recovery sequences...
January 6, 2018: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29306252/the-diagnostic-accuracy-of-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-ebus-tbna-in-mediastinal-tuberculous-lymphadenitis
#18
Onur Fevzi Erer, Serhat Erol, Ceyda Anar, Can Biçmen, Zekiye Aydoğdu, Serir Aktoğu
Background/aim: Mediastinal lymph nodes are the second most commonly affected lymph nodes in tuberculous lymphadenitis. It is often difficult to diagnose tuberculosis in patients with lymphadenopathy without parenchymal lesions. The aim of this study was to describe the diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with isolated mediastinal tuberculous lymphadenitis (MTLA). Materials and methods: This study included 527 patients who had undergone EBUS-TBNA between December 2012 and December 2014...
December 19, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29303284/-current-approach-to-diagnostics-treatment-and-prevention-of-tuberculosis
#19
Martina Vašáková
Tuberculosis is world-wide spread infectious disease with persistant high incidence, mainly in the densely populated countries with low income. Czech Republic belongs to the countries with highly efficient control of tuberculosis and continuously decreasing incidence of the disease. High-risk population for tuberculosis in the Czech Republic are the homeless people, who together with migrants from the countries with high incidence of tuberculosis represent reservoir of infection for our population. Treatment of tuberculosis is long-term, combined and controlled...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29302563/hemiplegia-as-a-presentation-of-hiv-infection-in-children-a-report-of-3-cases
#20
Ira Shah, Sneha Nandy, Renu Kumari
Strokes are a rare neurological manifestation of HIV infection in children with multifactorial etiologies. We present three HIV-infected children who presented to us with stroke out of which two had cerebral infarcts and who responded to antiretroviral therapy (ART). Third patient had tuberculous meningitis who was lost to follow-up before ART could be initiated.
April 2017: Journal of Family Medicine and Primary Care
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