keyword
https://read.qxmd.com/read/38466986/extrapulmonary-chronic-septic-arthritis-from-mycobacterium-tuberculosis-in-the-ankle-and-subtalar-joints
#21
JOURNAL ARTICLE
Tyson Compton, Nicholas Andrew Ferguson, Laura Certain, Devon Nixon
In the United States, rates of Mycobacterium tuberculosis infection have been declining for decades. Osteoarticular tuberculosis of the ankle is rarely observed. We present the case of a 65-year-old man who immigrated to the United States from India 24 years before the onset of symptoms. The patient initially reported atraumatic swelling and pain of the left ankle and foot and was treated for venous insufficiency. Later, the patient was referred to a nonsurgical orthopaedic clinic for additional workup and was found to have elevated inflammatory markers...
March 1, 2024: Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews
https://read.qxmd.com/read/38465128/challenges-and-triumphs-unusual-presentation-of-tuberculosis-in-the-cuboid-bone-successfully-managed-through-surgical-and-medical-intervention
#22
Hardik Patel, Sandeep Shrivastava, Aditya Pundkar, Ankit M Jaiswal, Saksham Goyal
This case report describes the unusual presentation of tuberculosis (TB) affecting the cuboid bone in a 16-year-old male patient. The patient presented with a one-year history of progressive foot pain, a discharging sinus, evening rise of temperature, weight loss, and loss of appetite. Clinical examination revealed soft tissue swelling and the presence of caseous material oozing from the sinus. Emergency debridement and curettage were performed, and bone cementing was carried out. An intraoperative sample was sent for a culture sensitivity test, histological analysis, and cartridge-based nucleic acid amplification test (CBNAAT)...
February 2024: Curēus
https://read.qxmd.com/read/38464928/acute-pancreatitis-as-a-complication-of-acute-covid-19-in-kidney-transplant-recipients
#23
JOURNAL ARTICLE
Nikolina Basic-Jukic, Ivana Juric, Lea Katalinic, Vesna Furic-Cunko, Vibor Sesa, Anna Mrzljak
BACKGROUND: Acute pancreatitis is a rare extrapulmonary manifestation of coronavirus disease 2019 (COVID-19) but its full correlation with COVID-19 infection remains unknown. AIM: To identify acute pancreatitis' occurrence, clinical presentation and outcomes in a cohort of kidney transplant recipients with acute COVID-19. METHODS: A retrospective observational single-centre cohort study from a transplant centre in Croatia for all adult renal transplant recipients with a functioning kidney allograft between March 2020 and August 2022 to record cases of acute pancreatitis during acute COVID-19...
February 26, 2024: World Journal of Clinical Cases
https://read.qxmd.com/read/38464574/legionella-induced-dysarthria-and-rhabdomyolysis-with-acute-renal-failure-achieving-recovery
#24
Husam El Sharu, Soban Ahmad, Hunter Coore
KEY CLINICAL MESSAGE: Legionnaires' disease, often presenting as pneumonia, can uncommonly manifest with extrapulmonary symptoms such as cerebellar involvement and rhabdomyolysis. This case emphasizes the successful resolution of dysarthria and renal dysfunction with prompt Legionella treatment, underscoring the importance of vigilance for diverse manifestations in Legionella infections. ABSTRACT: Legionnaires' disease usually presents with pneumonia and a few extrapulmonary manifestations, such as neurological, musculoskeletal, and cutaneous manifestations...
March 2024: Clinical Case Reports
https://read.qxmd.com/read/38461123/symptoms-and-quality-of-life-in-adults-with-cystic-fibrosis-a-cross-sectional-analysis-of-the-inspire-cf-trial
#25
JOURNAL ARTICLE
Natalia Smirnova, Jane Lowers, Alexandre Cammarata-Mouchtouris, Elisabeth P Dellon, Anne Fitzpatrick, Dio Kavalieratos
BACKGROUND: People living with cystic fibrosis (CF) experience a high symptom burden. Due to the changing landscape of CF in the era of modulator therapy, we sought to examine the epidemiology of symptoms and their association with quality of life, to help CF clinicians improve symptom screening in clinic. METHODS: Using baseline data from a trial of specialist palliative care in adults with CF, we examined symptom prevalence, distress, and association with quality of life (measured with the Functional Assessment of Chronic Illness Therapy Total Score)...
March 8, 2024: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://read.qxmd.com/read/38456644/characterization-of-mycobacterium-orygis-mycobacterium-bovis-and-mycobacterium-caprae-infections-in-humans-in-western-canada
#26
JOURNAL ARTICLE
Nicholas D Riopel, Richard Long, Courtney Heffernan, Gregory J Tyrrell, Cary Shandro, Vincent Li, Md Rashedul Islam, Michael Stobart, Meenu K Sharma, Hafid Soualhine, Ryan Cooper
Epidemiologic research on zoonotic tuberculosis historically used Mycobacterium bovis as a surrogate measure, however, increased reports of human tuberculosis caused by other animal-associated Mycobacterium tuberculosis complex members like Mycobacterium orygis necessitates their inclusion. We performed a retrospective cohort study including persons infected with any animal-lineage M. tuberculosis complex species in Alberta, Canada, from January 1995 to July 2021, identifying 42 patients (20 M. bovis, 21 M...
March 8, 2024: Journal of Infectious Diseases
https://read.qxmd.com/read/38453823/ectopic-epipericardial-fat-necrosis-a-case-report
#27
JOURNAL ARTICLE
Ryusei Yoshino, Masaki Nakatsubo, Nanami Ujiie, Akane Ito, Nana Yoshida, Naoko Aoki, Masahiro Kitada
BACKGROUND: Epipericardial fat necrosis (EFN) is a rare disease in which local inflammation and necrosis occur in the adipose tissue surrounding the heart, particularly epicardial fat. Few cases of EFN in which surgical resection was performed have been reported. We report a case of EFN after surgical resection of a right extrapulmonary tumor, in which a malignant disease could not be excluded. CASE PRESENTATION: A 75-year-old male patient presented with fever and chest pain...
March 8, 2024: Surgical Case Reports
https://read.qxmd.com/read/38441352/a-left-sided-destroyed-lung-in-a-11-year-old-girl-a-rare-sequela-after-mycoplasma-pneumoniae-infection
#28
JOURNAL ARTICLE
Maoyi Zuo, Hao Wang, Huaping Zhu
Mycoplasma pneumoniae infection is one of the most common causes of community-acquired pneumonia in children, usually experiencing a favorable prognosis.Cases of M. pneumoniae infection resulting in respiratory failure, severe pulmonary or extrapulmonary sequelae, and death are relatively rare.Currently, no cases related to a destroyed lung with Mycoplasma-associated infection have been reported.Therefore, we report a case of a destroyed lung in an 11-year-old girl with Mycoplasma-associated infection.
March 5, 2024: Pediatric Pulmonology
https://read.qxmd.com/read/38440213/assessing-the-utility-of-truenat-in-extrapulmonary-tuberculosis-diagnosis-a-nrl-s-experience
#29
JOURNAL ARTICLE
Priya Rajendran, Lavanya Jayabal, Mythili Venkatesan, Michel Prem Kumar, Radhakrishnan Ramalingam, P Sivaraman, Asha Fredrick, Sivakumar Shanmugam
BACKGROUND: Diagnosis of extra pulmonary TB (EPTB) remains a big challenge. While data on utility of Xpert testing in EPTB diagnosis is enormous, there is limited data on Truenat MTB testing. AIM: In this study we aimed to evaluate the usefulness of Truenat in EPTB diagnosis. MATERIALS AND METHODS: The study included patients suspected and/or treated for EPTB located from Chennai district during the year 2021-2022. All processed EPTB samples were subjected to smear microscopy, culture and Truenat MTB testing...
May 2024: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
https://read.qxmd.com/read/38438834/diagnosis-of-multiple-tuberculous-muscle-abscesses-in-a-patient-with-systemic-lupus-erythematosus-by-metagenomic-next-generation-sequencing-a-case-report-and-literature-review
#30
JOURNAL ARTICLE
Liu Wentao, Xie Shuxia, Zhu Guoxing, Chen Qiaoping, Chen Peiran, Wu Angela, Li Meirong, Yin Songchao, Feng Peiying
BACKGROUND: Early diagnosis of muscular tuberculosis (TB) without coexistent active skeletal involvement is often challenging because the disease is very rare and its clinical manifestation is nonspecific and misleading. To raise the awareness and emphasize early diagnosis of muscular TB, we present a case of multiple tuberculous muscle abscesses in a systemic lupus erythematosus (SLE) female, but without pulmonary tuberculosis (PTB), in order to increase awareness of and stress the need of early detection of muscular TB...
March 4, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38435136/hydatid-cyst-of-the-inguinal-region-an-exceptional-localization
#31
Mokhtari Omar, El Mahjoubi Sohaib, Adnane Lachkar, Najib Abdeljaouad, Hicham Yacoubi
Cystic echinococcosis (CE), stemming from the larval stage of the cestode Echinococcus granulosus , stands as a widespread parasitic zoonosis primarily afflicting the liver and lungs. However, instances in the inguinal region are exceptionally infrequent. We present a distinctive case involving a 49-year-old female with a progressively enlarging inguinal mass over a five-year period, characterized by the absence of hepatic or pulmonary involvement. This case underscores the unique clinical presentation and diagnostic intricacies associated with extrahepatic and extrapulmonary expressions of CE...
February 2024: Curēus
https://read.qxmd.com/read/38434388/prevalence-treatment-outcomes-and-determinants-of-tb-hiv-coinfection-a-4-year-retrospective-review-of-national-tuberculosis-registry-in-a-country-in-a-mena-region
#32
JOURNAL ARTICLE
Seyedeh Vajiheh Kazemian, Mohammadtaghi Shakeri, Eisa Nazar, Mahshid Nasehi, Saeid Sharafi, Maliheh Dadgarmoghaddam
BACKGROUND: The co-occurrence of tuberculosis (TB) and AIDS (HIV) has emerged as a significant public health challenge. This study investigated the epidemiological factors and treatment outcomes of TB in individuals based on their HIV status in Iran. METHODS: The current study was a descriptive-analytical cross-sectional study that focused on new patients diagnosed with TB in Iran between 2018 and 2021. Patients' data were sourced from the National Tuberculosis Registry database of Iran...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38427810/adrenal-morphology-and-cortical-function-in-patients-with-extrapulmonary-tuberculosis-response-to-antituberculosis-treatment
#33
JOURNAL ARTICLE
Bashir Ahmad Laway, Bhanu Pratap Singh Blouria, Rafi Ahmad Jan, Moomin Hussain Bhat, Naseer Ahmad Choh
OBJECTIVE: Enlargement of the adrenal glands and variable adrenocortical function have been reported in patients with pulmonary tuberculosis and, in a few studies, in patients with extrapulmonary tuberculosis (EPTB). However, none of the studies have evaluated the course of the adrenal morphology in these patients. SUBJECTS AND METHODS: Prospective study including 37 patients with EPTB and 37 healthy age- and sex-matched controls. The adrenal function was evaluated by measurement of cortisol levels at baseline and after stimulation with ACTH (Acton Prolongatum) before and 6 months after antituberculosis treatment...
February 29, 2024: Archives of Endocrinology and Metabolism
https://read.qxmd.com/read/38426596/the-influence-of-the-post-hepatic-septum-and-abdominal-volume-on-breathing-mechanics-in-the-lizard-salvator-merianae-dum%C3%A3-ril-bibron-1839-squamata-teiidae
#34
JOURNAL ARTICLE
Alan Marini, Renan Festuccia da Silva, Ray Brasil Bueno de Souza, Wilfried Klein
Teiid lizards possess an incomplete post-hepatic septum (PHS) separating the lungs and liver from the remaining viscera and within this group, Salvator merianae has the most complete PHS. In this study, we explored the combined effects of the presence of the PHS and alterations in abdominal volume on the mechanics of the respiratory system. The PHS is believed to act as a mechanical barrier, mitigating the impact of the viscera on the lungs. Using established protocols, we determined static (Cstat) and dynamic (Cdyn) compliance, lung volumes, and work of breathing for the respiratory system in tegu lizards with intact (PHS+) or removed (PHS-) PHS, combined with (balloon+) or without (balloon-) increased abdominal volume...
March 1, 2024: Journal of Experimental Biology
https://read.qxmd.com/read/38415334/systematic-review-and-meta-analysis-of-the-prevalence-incidence-and-treatment-outcomes-of-tuberculosis-in-egypt-updated-overview
#35
JOURNAL ARTICLE
Mohamed O Nour, Sameh O Nour
BACKGROUND: Tuberculosis (TB) is a major cause of morbidity and mortality globally. Understanding its epidemiology and burden is critical for targeted interventions. AIM: To highlight the prevalence, incidence and treatment outcomes of TB in Egypt during the last 2 decades. METHODS: For this systematic review and meta-analysis, we searched Medline/PubMed, ResearchGate, Google Scholar, and Scopus databases. We searched the local databases for unpublished studies, and the reports of international agencies, applying clear inclusion and exclusion criteria...
January 21, 2024: Eastern Mediterranean Health Journal
https://read.qxmd.com/read/38414860/investigation-of-vagal-sensory-neurons-in-mice-using-optical-vagal-stimulation-and-tracheal-neuroanatomy
#36
JOURNAL ARTICLE
Aung Aung Kywe Moe, Tara G Bautista, Matthew W Trewella, Willian S Korim, Song T Yao, Robert Behrens, Alexandria K Driessen, Alice E McGovern, Stuart B Mazzone
In rats and guinea pigs, sensory innervation of the airways is derived largely from the vagus nerve, with the extrapulmonary airways innervated by Wnt1+ jugular neurons and the intrapulmonary airways and lungs by Phox2b+ nodose neurons; however, our knowledge of airway innervation in mice is limited. We used genetically targeted expression of enhanced yellow fluorescent protein-channelrhodopsin-2 (EYFP-ChR2) in Wnt1+ or Phox2b+ tissues to characterize jugular and nodose-mediated physiological responses and airway innervation in mice...
March 15, 2024: IScience
https://read.qxmd.com/read/38414684/hepatic-tuberculosis-manifested-as-hepatic-abscess-a-report-of-a-unique-case
#37
Nilesh Jagdale, Vutukuru Kalyan Kumar Reddy, Mohith Prakash Kondapalli, Saimounika Adapa, Diksha Sabharwal
Millions of people around the world suffer from tuberculosis (TB), a long-term contagious illness. TB can invade almost all human body systems, with the respiratory system being the most impacted. Hepatic TB is a form of TB infection that affects the liver. It is considered an extrapulmonary manifestation of TB, which is a rare manifestation. Early identification of hepatic TB allows for prompt treatment, while leaving it untreated can result in fatality. Our patient is a 46-year-old female who presented with fever, weight loss, loss of appetite, and abdominal pain...
January 2024: Curēus
https://read.qxmd.com/read/38412542/cardiac-tuberculosis-a-case-series-from-ethiopia-italy-and-uganda-and-a-literature-review
#38
JOURNAL ARTICLE
Sergio Cotugno, Giacomo Guido, Giorgia Manco Cesari, Jerry Ictho, Peter Lochoro, James Amone, Francesco Vladimiro Segala, Elda De Vita, Rossana Lattanzio, Samuel Okori, Giuseppina De Iaco, Adisu Girma, Abata Sura, Eriballo Tariku Hessebo, Franco Balsemin, Giovanni Putoto, Luigi Ronga, Fabio Manenti, Enzo Facci, Annalisa Saracino, Francesco Di Gennaro
Extrapulmonary tuberculosis (TB) is estimated to account for up to 20% of active cases of TB disease, but its prevalence is difficult to ascertain because of the difficulty of diagnosis. Involvement of the heart is uncommon, with constrictive pericarditis being the most common cardiac manifestation. Diagnostic research for cardiac disease is frequently lacking, resulting in a high mortality rate. In addition to direct cardiac involvement, instances of cardiac events during antitubercular therapy are described...
February 27, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38409977/primary-orbital-tuberculosis-with-cold-abscess-a-case-report
#39
JOURNAL ARTICLE
Sanam Dhakal, Sulochana Neupane, Prerna Arjyal Kafle, Badri Prasad Badhu, Santosh Upadhyaya Kafle
UNLABELLED: Orbital tuberculosis is a rare form of extrapulmonary tuberculosis involving orbital soft tissue, periosteum, bones and lacrimal glands. This is a case report of a 6-year-old male child who presented with swelling of the right upper eyelid. He had normal visual acuity without signs of diplopia or ophthalmoplegia. The tuberculin skin test was reactive and the computed tomography scan showed peripherally enhancing collection with bony erosion and intracranial extension in the extraconal space of the superolateral right orbit...
February 24, 2024: JNMA; Journal of the Nepal Medical Association
https://read.qxmd.com/read/38409129/effects-of-body-awareness-therapy-on-balance-and-fear-of-falling-in-patients-with-chronic-obstructive-pulmonary-disease-a-randomized-controlled-trial
#40
JOURNAL ARTICLE
Seda Karaca, Aysel Yildiz Özer, Sait Karakurt, Mine Gülden Polat
BACKGROUND: Assessment of extrapulmonary comorbidities is essential in chronic obstructive pulmonary disease (COPD). Deterioration of balance and increasing fear of falling are two of the most significant extrapulmonary manifestations. Although pulmonary rehabilitation (PR) is well-known and effective for COPD patients, there is a need for alternative treatments to enhance balance and alleviate concerns about falling. This study aimed to investigate the effect of Body Awareness Therapy (BAT), in addition to the PR program, on balance and fear of falling in patients with COPD...
February 26, 2024: BioPsychoSocial Medicine
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