keyword
MENU ▼
Read by QxMD icon Read
search

Nutraceutical

keyword
https://www.readbyqxmd.com/read/29454074/nutraceuticals-as-therapeutic-agents-for-atherosclerosis
#1
REVIEW
Joe W E Moss, Jessica O Williams, Dipak P Ramji
Atherosclerosis, a chronic inflammatory disorder of medium and large arteries and an underlying cause of cardiovascular disease (CVD), is responsible for a third of all global deaths. Current treatments for CVD, such as optimized statin therapy, are associated with considerable residual risk and several side effects in some patients. The outcome of research on the identification of alternative pharmaceutical agents for the treatment of CVD has been relatively disappointing with many promising leads failing at the clinical level...
February 14, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29451029/screening-of-ionic-liquids-for-extraction-of-flavonoids-from-heather
#2
Paulina Dróżdż, Krystyna Pyrzynska
Room temperature ionic liquids are novel solvents with the specific properties that makes them of interest for application for extraction for a wide range of compounds. In this work extraction efficiency of flavonoids from heather flowers using ionic liquids based on imidazolium cation were evaluated and compared with organic solvents. It was found that the anion of ionic liquid significantly influence the extraction yields. Flavonoid content as well as antioxidant activity based on radical scavenging on 1,1-diphenul-2-pirylhydrazyl radicals and cupric reducing antioxidant capacity increased in the order: [Bmim]PF 6 < [Bmim]BF 4 < [Bmim]Cl...
February 16, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29449636/structural-elucidation-of-a-polysaccharide-from-flammulina-velutipes-and-its-immunomodulation-activities-on-mouse-b-lymphocytes
#3
Wen-Han Wang, Jing-Song Zhang, Ting Feng, Jing Deng, Chi-Chung Lin, Hua Fan, Wen-Juan Yu, Hai-Ying Bao, Wei Jia
A novel polysaccharide FVPB2 was purified from fruiting bodies of Flammulina velutipes. Its structure was elucidated by monosaccharide composition and methylation analyses, UV-Visible and FTIR spectroscopy as well as NMR. FVPB2 was a homogeneous heteropolysaccharide (molecular weight ~ 1.50 × 10 4 Da) containing D-galactose, D-mannose, L-fucose, and D-glucose at molar ratio of 1.9:1.2:1:2.5. In vitro immunomodulatory studies showed FVPB2 induced proliferation of mouse spleen lymphocytes in a dose-dependent manner...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29448931/effects-of-different-extracts-of-curcumin-on-tpc1-papillary-thyroid-cancer-cell-line
#4
Angelica Perna, Antonio De Luca, Laura Adelfi, Tammaro Pasquale, Bruno Varriale, Teresa Esposito
BACKGROUND: The thyroid gland is one of the largest endocrine glands in the body. The vast majority of TCs (> 90%) originate from follicular cells and are defined as differentiated thyroid cancers (DTC) and the two histological subtypes are the papillary TC with its variants and the follicular TC. Curcumin possesses a wide variety of biological functions, and thanks to its properties, it has gained considerable attention due to its profound medicinal values (Prasad, Gupta, Tyagi, and Aggarwal, Biotechnol Adv 32:1053-1064, 2014)...
February 15, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29447046/oral-curcumin-supplementation-improves-fine-motor-function-in-the-middle-aged-rhesus-monkey
#5
Tara L Moore, Bethany G E Bowley, Penny L Shultz, Samantha M Calderazzo, Eli J Shobin, Ajay R Uprety, Douglas L Rosene, Mark B Moss
Aged individuals experience decreased fine motor function of the hand and digits, which could result, in part, from the chronic, systemic state of inflammation that occurs with aging. Recent research for treating age-related inflammation has focused on the effects of nutraceuticals that have anti-inflammatory properties. One particular dietary polyphenol, curcumin, the principal curcuminoid of the spice turmeric, has been shown to have significant anti-inflammatory effects and there is mounting evidence that curcumin may serve to reduce systemic inflammation...
February 15, 2018: Somatosensory & Motor Research
https://www.readbyqxmd.com/read/29445414/effects-of-a-new-nutraceutical-combination-on-cognitive-function-in-hypertensive-patients
#6
Giuseppe Giugliano, Alessia Salemme, Sara De Longis, Marialuisa Perrotta, Valentina D'Angelosante, Alessandro Landolfi, Raffaele Izzo, Valentina Trimarco
Background: Chronic increased arterial blood pressure has been associated with executive dysfunction, slowing of attention and mental processing speed, and later with memory deficits. Due to the absence of a concrete therapeutic approach to this pathophysiological process, in the last decades there has been an increasing interest in the use of nutraceuticals, especially those with antioxidant properties, which own strong neuroprotective potential, that may help to improve cognitive function and to delay the onset of dementia...
2018: Immunity & Ageing: I & A
https://www.readbyqxmd.com/read/29438459/dietary-supplements-with-antiplatelet-activity-a-solution-for-everyone
#7
Beata Olas
Dietary supplements can have beneficial effects on a number of risk factors for cardiovascular diseases, and interest in the use of nonpharmacologic nutraceutical-based treatments for cardiovascular disorders is growing. The aim of this review is to present the role of dietary supplements with antiplatelet activity in the prophylaxis and treatment of cardiovascular disorders. In addition, this paper describes their effects on another very important element of hemostasis-blood coagulation. However, because controlled human clinical experiments are too limited to clearly identify the antiplatelet and anticoagulant properties of dietary supplements, used alone or in combination with classical antiplatelet therapy (e...
January 1, 2018: Advances in Nutrition
https://www.readbyqxmd.com/read/29437000/extraction-identification-and-biological-activities-of-saponins-in-sea-cucumber-pearsonothuria-graeffei
#8
Rafat Afifi Khattab, Mohamed Elbandy, Andrew Lawrence, Tim Paget, Jung Rae-Rho, Yaser S Binnaser, Imran Ali
AIM AND OBJECTIVE: Secondary metabolism in marine organisms produced a diversity of biological important natural compounds which are unpresented in terrestrial species. Sea cucumbers belong to the invertebrate Echinodermata and are famous for their nutraceutical, medical and food values. They are known for possession triterpenoid glycosides (saponins) with various ecological roles. The current work aimed to separate, identify and test various biological activities (anti-bacterial, antifungal, antileishmanial and anticancer properties) of saponins produced by the holothurian Pearsonothuria graeffei from the Red Sea, Egypt...
February 12, 2018: Combinatorial Chemistry & High Throughput Screening
https://www.readbyqxmd.com/read/29433806/non-vmat2-inhibitor-treatments-for-the-treatment-of-tardive-dyskinesia
#9
REVIEW
Chih-Chun Lin, William G Ondo
Although VMAT2-inhibitors are now established as first-line treatment for tardive dyskinesia, not all patients respond to, or tolerate them. Numerous other agents have been adopted to treat tardive dyskinesia, but with variable results and generally lower quality methodologic reports. Amantadine is the most promising but benzodiazepines, branched chain neutral amino acids, Vitamin B6, several nutraceuticals, and botulinum toxin injections might help some patients. In all cases, better placebo controlled trials are needed before definitive recommendations can be made...
February 5, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29433295/enhancing-the-physicochemical-stability-of-%C3%AE-carotene-solid-lipid-nanoparticle-slnp-using-whey-protein-isolate
#10
Bahar Mehrad, Raheleh Ravanfar, Jonathan Licker, Joe M Regenstein, Alireza Abbaspourrad
β-Carotene is a nutraceutical that acts as a coloring agent and as pro-vitamin A, but its incorporation into foods is limited because of its hydrophobicity and low chemical stability. The aim of this study was to improve the physicochemical stability of β-carotene by encapsulating into solid lipid nanoparticles (SLNPs) containing palmitic acid and corn oil, stabilized using whey protein isolate (WPI). The palmitic acid crystals covered the surface of the oil droplets and formed a solid shell to protect the encapsulated β-carotene...
March 2018: Food Research International
https://www.readbyqxmd.com/read/29433260/hydroxytyrosol-bioavailability-toxicity-and-clinical-applications
#11
REVIEW
María Robles-Almazan, Mario Pulido-Moran, Jorge Moreno-Fernandez, Cesar Ramirez-Tortosa, Carmen Rodriguez-Garcia, Jose L Quiles, MCarmen Ramirez-Tortosa
Many beneficial properties have been attributed to the Mediterranean diet. Over the years, researchers have attempted to learn which foods and which food components are responsible for good health. One of these components is hydroxytyrosol, an important phenolic compound present in olive oil. Hydroxytyrosol is a molecule of high interest to the pharmaceutical industry due to its anti-inflammatory and antimicrobial qualities its role against cardiovascular diseases and metabolic syndrome and for its neuroprotection, antitumour, and chemo modulation effects...
March 2018: Food Research International
https://www.readbyqxmd.com/read/29433242/changes-in-extra-virgin-olive-oil-added-with-lycium-barbarum-l-carotenoids-during-frying-chemical-analyses-and-metabolomic-approach
#12
F Blasi, G Rocchetti, D Montesano, L Lucini, G Chiodelli, S Ghisoni, G Baccolo, M S Simonetti, L Cossignani
In this work, an Italian extra-virgin olive oil (EVOO) sample and the same sample added with a carotenoid-rich nutraceutical extract from Lycium barbarum L. (EVOOCar) were subjected to a frying process to comparatively assess chemical and physical changes and heat stability. Oxidation progress was monitored by measuring oil quality changes such as peroxide value, free acidity, K232, K268, and fatty acid composition as well as minor compound content, phenols, α-tocopherol, and carotenoids. An UHPLC/QTOF-MS metabolomics approach discriminated the two oil samples based on their chemical changes during frying, identifying also the phenolic classes most exposed to statistically significant variations...
March 2018: Food Research International
https://www.readbyqxmd.com/read/29433234/effect-of-xanthan-gum-on-lipid-digestion-and-bioaccessibility-of-%C3%AE-carotene-loaded-rice-starch-based-filled-hydrogels
#13
Shinjae Park, Saehun Mun, Yong-Ro Kim
The aim of this study was to examine the effects of xanthan gum on the lipid digestibility, rheological properties, and β-carotene bioaccessibility of rice starch-based filled hydrogels. β-Carotene was solubilized within lipid droplets of emulsion that were then entrapped within rice starch hydrogels fabricated with different concentrations of xanthan gum. At a low concentration of xanthan gum (<0.5wt%), the viscous characteristics of the filled starch hydrogels increased. Furthermore, these hydrogels had a slower rate of lipid digestion than the β-carotene-loaded emulsion...
March 2018: Food Research International
https://www.readbyqxmd.com/read/29433229/in-vitro-chemopreventive-properties-of-peptides-released-from-quinoa-chenopodium-quinoa-willd-protein-under-simulated-gastrointestinal-digestion
#14
Rubén Vilcacundo, Beatriz Miralles, Wilman Carrillo, Blanca Hernández-Ledesma
Because of the continuous and direct interaction between the digestive tract and foods, dietary compounds represent an interesting source of chemopreventive agents for gastrointestinal health. In this study, the influence of a standardized static in vitro gastrointestinal digestion model on the release of peptides with chemopreventive potential from quinoa protein was investigated. Gastroduodenal digests and fractions collected by ultrafiltration were evaluated for their in plate oxygen radical absorbance capacity and in vitro colon cancer cell viability inhibitory activity...
March 2018: Food Research International
https://www.readbyqxmd.com/read/29433203/physicochemical-and-nutraceutical-properties-of-moringa-moringa-oleifera-leaves-and-their-effects-in-an-in-vivo-aom-dss-induced-colorectal-carcinogenesis-model
#15
M L Cuellar-Nuñez, I Luzardo-Ocampo, R Campos-Vega, M A Gallegos-Corona, E González de Mejía, G Loarca-Piña
Moringa (Moringa oleifera) is a plant that has generated great interest in recent years because of its attributed medicinal properties. The aim of this study was to characterize the bioactive compounds of moringa leaves (MO) and evaluate their effect on a colorectal carcinogenesis model. Twenty-four male CD-1 mice were divided into 4 groups: Group 1 fed with basal diet (negative control/NC); Group 2 received AOM/DSS (positive control); Groups 3 and 4 were fed with basal diet supplemented with moringa leaves (2...
March 2018: Food Research International
https://www.readbyqxmd.com/read/29433194/uplc-qtof-ms-profiling-of-two-psidium-species-and-the-in-vivo-hepatoprotective-activity-of-their-nano-formulated-liposomes
#16
Fatema R Saber, Ghada A Abdelbary, Maha M Salama, Dalia O Saleh, Magda M Fathy, Fathy M Soliman
Liver diseases are major health problem in Egypt influencing lifestyle and economy. The demand for nutraceutical hepatoprotective agents is crucial to ameliorate the side effects of synthetic drugs. The present study aims to evaluate antioxidant and hepatoprotective activities of extracts of Psidium guajava L. and Psidium cattleianum Sabine leaves and their nano-formulated liposomes against paracetamol-induced liver damage in rats. Secondary metabolites profile of P. guajava and P. cattleianum leaves was investigated using UPLC-PDA-ESI-qTOF-MSn...
March 2018: Food Research International
https://www.readbyqxmd.com/read/29433155/nutraceuticals-opening-the-debate-for-a-regulatory-framework
#17
REVIEW
Antonello Santini, Silvia Miriam Cammarata, Giacomo Capone, Angela Ianaro, Giancarlo Tenore, Luca Pani, Ettore Novellino
Currently, nutraceuticals do not have a specific definition distinct from those of other food-derived categories, e.g., food supplements, herbal products, pre- and probiotics, functional foods, and fortified foods. Many studies have led to an understanding of the potential mechanisms of action of pharmaceutically active components contained in food that may improve health and reduce the risk of pathological conditions while enhancing overall well-being. Nevertheless, there is a lack of clear information, and often, the claimed health benefits may not be properly substantiated by safety and efficacy information and in vitro and in vivo data, which can induce false expectations and miss the target for a product to be effective, as claimed...
February 12, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29432917/polyphenol-extracts-from-dried-sugarcane-inhibit-inflammatory-mediators-in-an-in-vitro-colon-cancer-model
#18
Daniel Bucio-Noble, Liisa Kautto, Christoph Krisp, Malcolm S Ball, Mark P Molloy
Sugarcane is an important crop grown in tropical regions for sugar, and for ethanol production. Sugarcane is also a source of phytochemicals but its nutraceutical potential has been under-explored. We show that ethanol extracts of whole dried sugarcane (WDS) recovers a rich content of polyphenols, flavonoids and antioxidant activity that act on inflammatory mediator proteins. To investigate the mechanisms of this activity, we stimulated SW480 colon cancer cells with lipopolysaccharide, exposed cells to WDS and quantitated changes to the proteome and phosphoproteome using label-free mass spectrometry...
February 10, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29429679/intensified-synthesis-of-medium-chain-triglycerides-using-ultrasonic-reactors-at-a-capacity-of-4l
#19
Ashish V Mohod, Parag R Gogate
Lipids are considered as one of the most crucial nutrients for humans and among the various classes, medium chain triglycerides (MCTs) are considered as the most important functional foods and nutraceuticals. The present work deals with the intensification of synthesis of MCTs at a large capacity of 4L based on the use of ultrasonic bath and ultrasonic longitudinal horn. The effect of operating parameters like molar ratio of the reactants, type of catalyst and catalyst loading as well as the temperature on the extent of conversion has been investigated...
April 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29429599/behavioral-nutraceuticals-and-diets
#20
REVIEW
Jillian M Orlando
Behavioral problems of companion animals are becoming more widely recognized. As a result, there are a growing number of behavioral nutraceuticals and diets on the market. These products may be useful for the treatment of mild conditions, for clients who are hesitant to give their pet a psychopharmacologic agent, or sometimes in conjunction with psychopharmacologic agents. Veterinarians should critically review the research associated with nutraceuticals and diets, and have an understanding of the functional ingredients and their mechanisms of action before prescribing treatment...
February 8, 2018: Veterinary Clinics of North America. Small Animal Practice
keyword
keyword
11446
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"