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Shoko Ono, Satoshi Abiko, Mototsugu Kato
Gastric intestinal metaplasia (GIM) is a high risk for intestinal type gastric cancer; however, there is a limitation for detection of GIM using white light imaging (WLI). Image-enhanced endoscopy (IEE) is more advantageous than WLI for optical diagnosis of GIM (1). Linked color imaging (LCI) (FUJIFILM Co., Tokyo, Japan) was newly developed for advanced IEE and enables visualization of red lesions that appear redder and whitish red lesions that appear whiter during routine endoscopy (2). GIM is observed as a lavender color that is distinguishable from the circumferential mucosa without GIM by using LCI (Figure 1)...
October 22, 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
Daniel Shane Wright, Nicolle Demandt, Jeroen T Alkema, Ole Seehausen, Ton G G Groothuis, Martine E Maan
Local adaptation can be a potent force in speciation, with environmental heterogeneity leading to niche specialization and population divergence. However, local adaption often requires non-random mating in order to generate reproductive isolation. Population divergence in sensory properties can be particularly consequential in speciation, affecting both ecological adaptation and sexual communication. Pundamilia pundamila and Pundamilia nyererei are two closely related African cichlid species that differ in male coloration, blue vs...
October 22, 2016: Journal of Evolutionary Biology
A W Carr, M Saffman
We analyze doubly magic trapping of Cs hyperfine transitions including previously neglected contributions from the ground state hyperpolarizability and the interaction of the laser light and a static magnetic field. Extensive numerical searches do not reveal any doubly magic trapping conditions for any pair of hyperfine states. However, including the hyperpolarizability reveals light intensity insensitive traps for a wide range of wavelengths at specific intensities. We then investigate the use of bichromatic trapping light fields...
October 7, 2016: Physical Review Letters
Hamid Reza Samadikhah, Maryam Nikkhah, Saman Hosseinkhani
Two quantum dots (QDs), a green emitter, CdSe and a red emitter, CdSe with ZnS shell are encapsulated into novel liposomes in two different formulations including cationic liposomes. Quantum dots have proven themselves as powerful inorganic fluorescent probes, especially for long-term, multiplexed imaging and detection. Upon delivery into a cell, in endocytic vesicles such as endosomes, their fluorescence is quenched. We have investigated the potential toxic effects, photophysical properties and cell internalization of QDs in new formulation of liposomes as an in vitro vesicle model...
October 21, 2016: Luminescence: the Journal of Biological and Chemical Luminescence
Gaigai Yu, Hiroyuki Onodera, Yuki Aono, Fuun Kawano, Yoshibumi Ueda, Akihiro Furuya, Hideyuki Suzuki, Moritoshi Sato
Alpha subunits of heterotrimeric G proteins (Gα) are involved in a variety of cellular functions. Here we report an optogenetic strategy to spatially and temporally manipulate Gα in living cells. More specifically, we applied the blue light-induced dimerization system, known as the Magnet system, and an alternative red light-induced dimerization system consisting of Arabidopsis thaliana phytochrome B (PhyB) and phytochrome-interacting factor 6 (PIF6) to optically control the activation of two different classes of Gα (Gαq and Gαs)...
October 21, 2016: Scientific Reports
Angie D Ambers, Jennifer D Churchill, Jonathan L King, Monika Stoljarova, Harrell Gill-King, Mourad Assidi, Muhammad Abu-Elmagd, Abdelbaset Buhmeida, Bruce Budowle
BACKGROUND: Although the primary objective of forensic DNA analyses of unidentified human remains is positive identification, cases involving historical or archaeological skeletal remains often lack reference samples for comparison. Massively parallel sequencing (MPS) offers an opportunity to provide biometric data in such cases, and these cases provide valuable data on the feasibility of applying MPS for characterization of modern forensic casework samples. In this study, MPS was used to characterize 140-year-old human skeletal remains discovered at a historical site in Deadwood, South Dakota, United States...
October 17, 2016: BMC Genomics
Roger Duarte de Melo, Daniel Acosta-Avalos
'Candidatus Magnetoglobus multicellularis' is the most studied multicellular magnetotactic prokaryote. It presents a light-dependent photokinesis: green light decreases the translation velocity whereas red light increases it, in comparison to blue and white light. The present article shows that radio-frequency electromagnetic fields cancel the light effect on photokinesis. The frequency to cancel the light effect corresponds to the Zeeman resonance frequency (DC magnetic field of 4 Oe and radio-frequency of 11...
October 20, 2016: Antonie Van Leeuwenhoek
P K Prasanth Kumar, T Jeyarani, A G Gopala Krishna
Phytonutrients retained palm olein (PRPOL) was prepared and blended into butterfat at different ratios. The physicochemical characteristics and the phytonutrient composition of blends, as well as its utilization in the preparation of functional chocolate spread were evaluated. The results showed that the redness, yellowness, slip melting point, free fatty acids, peroxide value, iodine value, unsaponifiable matter, diacylglycerol and monoacylglycerol increased while lightness, saponification value, and triacylglycerol significantly decreased upon incorporation of increased quantities of PRPOL into butterfat...
July 2016: Journal of Food Science and Technology
Monique Narciso Alba, Marli Gerenutti, Valquíria Miwa Hanai Yoshida, Denise Grotto
Acne vulgaris treatments usually cause sensitivity, teratogenicity and bacterial resistance. Investigations of others therapeutic techniques, such as phototherapy, is highly relevant. Thus, we compared the effectiveness of two Acne vulgaris treatments in adolescents: peeling with salicylic acid and phototherapy. Teens were randomly divided in: group I, treatment with salicylic acid peels (10 %) and group II, treatment with phototherapy (blue LED and red laser lights). Photographs were taken before and after ten sessions of each treatment, carried out weekly, and compared...
October 20, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Patricia Müller-Moulé, Kazunari Nozue, Melissa L Pytlak, Christine M Palmer, Michael F Covington, Andreah D Wallace, Stacey L Harmer, Julin N Maloof
Plants respond to neighbor shade by increasing stem and petiole elongation. Shade, sensed by phytochrome photoreceptors, causes stabilization of PHYTOCHROME INTERACTING FACTOR proteins and subsequent induction of YUCCA auxin biosynthetic genes. To investigate the role of YUCCA genes in phytochrome-mediated elongation, we examined auxin signaling kinetics after an end-of-day far-red (EOD-FR) light treatment, and found that an auxin responsive reporter is rapidly induced within 2 hours of far-red exposure. YUCCA2, 5, 8, and 9 are all induced with similar kinetics suggesting that they could act redundantly to control shade-mediated elongation...
2016: PeerJ
Liina Pajusalu, Georg Martin, Tiina Paalme, Arno Põllumäe
Anthropogenic carbon dioxide (CO2) emissions to the atmosphere are causing reduction in the global ocean pH, also known as ocean acidification. This change alters the equilibrium of different forms of dissolved inorganic carbon in seawater that macroalgae use for their photosynthesis. In the Baltic Sea, benthic macroalgae live in a highly variable environment caused by seasonality and rapid changes in meteorological conditions. The effect of increasing water CO2 concentration on the net photosynthesis of the red macroalgae Furcellaria lumbricalis (Hudson) Lamouroux was tested in short-term mesocosm experiments conducted in Kõiguste Bay (N Gulf of Riga) in June-July 2012 and 2013...
2016: PeerJ
Balakrishnan Nirmal
Management of periungual wart is a great challenge, especially when there is subungual extension. The major cause of recurrence of wart is improper clinical assessment of its extent and not directing therapy against the entire wart. This difficulty of ascertaining its extent could be overcome with this finger-shaped red light emitting diode device. Red light in the device penetrates the thick palmar skin and dark constitutive skin colour due to its longer wavelength.
July 2016: Journal of Cutaneous and Aesthetic Surgery
Chunfeng Chen, Jie Chen, Tianyu Wang, Minghua Liu
Four kinds of commercially available diacetylene (DA) monomers with different chain length, diacetylene positions were fabricated into the organogels via mixing with a chaperone gelator, an amphiphilic L-histidine ester derivative LHC18 that can help the non-gelator to form gels. Upon photo irradiation with a 254 UV light, the white gels underwent topochemical reaction and turned into red or blue gels, depending on the DA monomer structures. Through the gel formation, the molecular chirality of LHC18 can be transferred to the polydiacetylene (PDA) and helical nanoribbon structures were obtained...
October 19, 2016: ACS Applied Materials & Interfaces
Mª Del Mar Blanquer-Rosselló, Reyniel Hernández-López, Pilar Roca, Jordi Oliver, Adamo Valle
BACKGROUND: The polyphenol resveratrol (RSV) is found in the skin of red grapes and has been reported to exhibit anticancer properties. The antitumor effects of RSV in the gastrointestinal tract have gained considerable interest due to the high exposure of this tissue to this dietary compound. One of the hallmarks of cancer cells is their particular metabolism mainly relying on glycolysis for ATP production rather than mitochondrial oxidative phosphorylation. Although RSV has been described to act as a calorie-restriction mimetic, modulating energy metabolism in normal tissues, little efforts have been done to study the effects of this polyphenol in the metabolism of cancer cells...
October 17, 2016: Biochimica et Biophysica Acta
Jaewook Kim, Kijong Song, Eunae Park, Keunhwa Kim, Gabyong Bae, Giltsu Choi
Seedling hypocotyls display negative gravitropism in the dark but agravitropism in the light. The Arabidopsis thaliana pif quadruple mutant (pifQ), which lacks four PHYTOCHROME-INTERACTING FACTORS (PIFs), is agravitropic in the dark. Endodermis-specific expression of PIF1 rescues gravitropism in pifQ mutant seedlings. Since phytochromes induce light responses by inhibiting PIFs and the COP1-SPA ubiquitin E3 ligase complex in the nucleus, we asked whether phyB can cell autonomously inhibit hypocotyl negative gravitropism in the endodermis...
October 6, 2016: Plant Cell
Xiaoyu Zhang, Chun Sun, Yu Zhang, Hua Wu, Changyin Ji, Yahui Chuai, Peng Wang, Shanpeng Wen, Chunfeng Zhang, William W Yu
The high photoluminescence efficiency, high color purity, and easy tunable bandgap make inorganic perovskite nanocrystals very attractive in luminescent display applications. Here, we report a color-saturated, red light-emitting diode (LED) using an inverted organic/inorganic hybrid structure and perovskite nanocrystals. We demonstrated that through a simple post treatment to the perovskite nanocrystals with polyethylenimine, the surface defects of the perovskite nanocrystals could be well passivated, leading to great enhancements on their absolute photoluminescence quantum yield and photoluminescence lifetime...
October 19, 2016: Journal of Physical Chemistry Letters
Yang-Seok Yoo, Jong-Ho Na, Sung Jin Son, Yong-Hoon Cho
A critical issue in GaN-based high power light-emitting diodes (LEDs) is how to suppress the efficiency droop problem occurred at high current injection while improving overall quantum efficiency, especially in conventional c-plane InGaN/GaN quantum well (QW), without using complicated bandgap engineering or unconventional materials and structures. Although increasing thickness of each QW may decrease carrier density in QWs, formation of additional strain and defects as well as increased built-in field effect due to enlarged QW thickness are unavoidable...
October 19, 2016: Scientific Reports
Nikolai N Sluchanko, Konstantin E Klementiev, Evgeny A Shirshin, Georgy V Tsoraev, Thomas Friedrich, Eugene G Maksimov
In Cyanobacteria, the Orange Carotenoid Protein (OCP) and Fluorescence Recovery Protein (FRP) are central to the photoprotective mechanism consisting in regulated quenching of phycobilisome (PBs) fluorescence. Due to a transient and flexible nature of the light-activated red quenching form, OCP(R), which is obtained from the stable dark-adapted orange form, OCP(O), by photoconversion, the detailed mechanism of photoprotection remains unclear. Here we demonstrate that our recently described W288A mutant of the Synechocystis OCP (hereinafter called OCP(W288A)) is a fully functional analogue of the OCP(R) form which is capable of constitutive PBs fluorescence quenching in vitro with no need of photoactivation...
October 15, 2016: Biochimica et Biophysica Acta
Nathan S Hart, Melinda Fitzgerald
Red-near-infrared light has been used for a range of therapeutic purposes. However, clinical trials of near-infrared laser light for treatment of stroke were abandoned after failing interim futility analyses. Lack of efficacy has been attributed to sub-optimal treatment parameters and low penetrance of light to affected brain regions. Here, we assess penetrance of wavelengths from 450-880 nm in human post-mortem samples, and demonstrate that human skin, skull bone and brain transmits therapeutically relevant quantities of light from external sources at wavelengths above 600nm...
September 2016: Discovery Medicine
Jason A Wiesinger, Karen A Cichy, Raymond P Glahn, Michael A Grusak, Mark A Brick, Henry J Thompson, Elad Tako
Dry beans (Phaseolus vulgaris L.) are a nutrient dense food rich in protein and micronutrients. Despite their nutritional benefits, long cooking times limit the consumption of dry beans worldwide, especially in nations where fuelwood for cooking is often expensive or scarce. This study evaluated the nutritive value of 12 dry edible bean lines that vary for cooking time (20 to 89 min) from four market classes (yellow, cranberry, light red kidney, and red mottled) of economic importance in bean consuming regions of Africa and the Americas...
October 18, 2016: Journal of Agricultural and Food Chemistry
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