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Red light

Glynis Ablon
Within the field of dermatology, advances in the use of light emitting diodes (LEDs) have led to their clinical application for a variety of medical and cosmetic uses. Of note, one phototherapy device has demonstrated beneficial effects over a range of clinical applications (Omnilux™; GlobalMed Technologies, Glen Ellen, California). The study included a literature review of published studies. Using LEDs with frequencies of 415nm (blue), 633nm (red), and 830nm (infrared), this device has demonstrated significant results for the treatment of medical conditions, including mild-to-moderate acne vulgaris, wound healing, psoriasis, squamous cell carcinoma in situ (Bowen's disease), basal cell carcinoma, actinic keratosis, and cosmetic applications...
February 2018: Journal of Clinical and Aesthetic Dermatology
Joshua T Byers, Xin Qing, Christopher Lo, Samuel W French, Ping Ji
Amyloidosis is a disorder characterized by the deposition of insoluble abnormal proteins in the extracellular space. It may occur as a localized lesion or as a systemic disease involving multiple organs and systems. Localized conjunctival amyloidosis is rare and is less frequently associated with systemic involvement. Although amyloidosis itself is a benign lesion involvement of multiple organs and systems is associated with poor prognosis. Diagnosis of amyloidosis is made on biopsy specimens with Congo red staining for the appearance of apple-green birefringence under polarized light microscopy...
March 15, 2018: Experimental and Molecular Pathology
Pedro Jorge Louro Crugeira, Gustavo M Pires-Santos, Susana C P S de Oliveira, Fernando José Pires Sampaio, Neandder Andrade Correia, Sandra R C de A Fagnani, Fabio Alexandre Chinalia, Paulo Fernando de Almeida, Antônio L B Pinheiro
Cellulose has a highly diversified architecture and its enzymatic complexes are studied for achieving an efficient conversion and a high level of efficiency in the deconstruction of cellulolytic biomass into sugars. The aim of this investigation was to evaluate the effect of Laser or LED light in the cellulolytic activity (CMCase) and on the proliferation of the thermophilic microbial consortium used on the degradation process of a lignocellulosic biomass of green coconut shell. The irradiation protocol consisted of six Laser irradiations (λ660 ηm, 40 mW, 270 s, 13 J/cm2 ) or LED (λ632 ± 2 ηm, 145 mW, 44 s, 13 J/cm2 ) with 12- h time intervals in nutrient deprivation conditions...
March 8, 2018: Journal of Photochemistry and Photobiology. B, Biology
Judith Stiefelmaier, Benjamin Ledermann, Michael Sorg, Angela Banek, Doris Geib, Roland Ulber, Nicole Frankenberg-Dinkel
Phycoerythrobilin (PEB) is an open-chain tetrapyrrole derived from heme and plays an important role as light-harvesting pigment in the phycobiliproteins of cyanobacteria and red algae. Furthermore, PEB can also function as an antioxidant with potential use as a natural acid stable food colorant. PEB is not commercially available and large, pure quantities can only be obtained by laborious methanolysis of red algae followed by liquid chromatography. Here we describe an improved method for high yield production and purification of PEB in Escherichia coli via heterologous expression where the two required enzymes heme oxygenase and PEB synthase subsequently convert the substrate heme provided by the host cell...
March 13, 2018: Journal of Biotechnology
A-Ra Hong, Youngsun Kim, Tae Sup Lee, Sehoon Kim, Kwangyeol Lee, Gayoung Kim, Ho Seong Jang
In this study, intense single-band red-emitting upconversion nanophosphors (UCNPs) excited with 800 nm near infrared (NIR) light are reported. When a NaYF4 :Nd,Yb active-shell is formed on the 12.7 nm-sized NaGdF4 :Yb,Ho,Ce UCNP core, the core/shell (C/S) UCNPs show tunable emission from green to red depending on the Ce3+ concentration under excitation with 800 nm NIR light. Thirty mol% Ce3+ -doped C/S UCNPs exhibit single-band red emission peaking at 644 nm via a5 F5 →5 I8 transition of Ho3+ . A high Nd3+ concentration in the shell results in strong absorption at around 800 nm NIR light even though the shell thickness is not large, and small-sized C/S UCNPs (16...
March 16, 2018: ACS Applied Materials & Interfaces
Varun Vohra, Francesco Galeotti, Umberto Giovanella, Wojciech Mroz, Mariacecilia Pasini, Chiara Botta
Push-coating is a green and extremely low-cost process in which only few microliters of conjugated polymer solutions are used to produce thin films using capillary forces. Here, we adapt this fabrication technique to replicate self-assembled nanoporous structures on green and red light-emitting conjugated polymer thin films. These films display ring-like photoluminescence and are successfully integrated into polymer light-emitting devices as emitting layers. At low applied voltages, the green-emitting devices exhibit electroluminescence from hexagonally arranged nanopixel arrays resulting from a stronger electric field in the thinner areas inside the pores...
March 16, 2018: ACS Applied Materials & Interfaces
Ruiyan Tao, Songling Bai, Junbei Ni, Qinsong Yang, Yuan Zhao, Yuanwen Teng
A conserved blue light sensing and transduction pathway contributes to blue light-induced anthocyanin accumulation in the peel of red pear. Peel color is an economically important characteristic that influences the appearance quality of red pear, whose red color is due to anthocyanin accumulation. The process of coloration in the fruit peel is strongly influenced by light. However, how light quality influences color development remains unclear. In this study, we analyzed the effects of different light qualities on color development in the red pear 'Red Zaosu', a mutant of the hybrid cultivar 'Zaosu' of Pyrus pyrifolia and P...
March 15, 2018: Planta
Louise Kruse Jensen, Nicole Lind Henriksen, Thomas Bjarnsholt, Kasper Nørskov Kragh, Henrik Elvang Jensen
Aim: Visualization of Staphylococcus aureus biofilm using histochemical staining and combined histochemistry (HC) and immunohistochemistry (IHC). Methods: The ability of S. aureus S54F9 to form biofilm was tested in vitro . Hereafter, infected bone tissue was collected from two different porcine models of osteomyelitis inoculated with S. aureus strain S54F9. The infection time was five and fifteen days, respectively. Twenty-five different histochemical staining protocols were tested in order to find the stains that could identify extracellular biofilm matrix...
2018: Journal of Bone and Joint Infection
Nigel Scrutton, Uzma Choudry, Derren Heyes, Samantha Hardman, Michiyo Sakuma, Igor Sazanovich, Joyce Woodhouse, Eugenio De La Mora, Martin Pederson, Michael Wulff, Martin Weik, Giorgio Schiro
Phytochromes are bilin-containing photoreceptors that are typically sensitive to the red / far-red region of the visible spectrum. Recently phytochromes from certain eukaryotic algae have become attractive targets for optogenetic applications because of their unique ability to respond to multiple wavelengths of light. Here, we have used a combination of time-resolved spectroscopy and structural approaches across picosecond to second timescales to map photochemical mechanisms and structural change in this atypical group of phytochromes...
March 15, 2018: Chembiochem: a European Journal of Chemical Biology
Julie Rivière, Yann Le Strat, Pascal Hendrikx, Barbara Dufour
Bovine tuberculosis (bTB) is a common disease of cattle and wildlife, with economic repercussions and implications for animal and human health. The surveillance of bTB in wildlife is particularly important, to shed light on the epidemiological role of wild species and for the adaptation of control measures. In France, a bTB surveillance system for free-ranging wildlife, the Sylvatub system, was launched in 2011 on wild boars, red deer, roe deer and badgers. It relies on active and passive surveillance activities, constrained by practical difficulties, such as the accessibility of wild animals, and regulatory rules for the trapping of badgers, for example...
2018: PloS One
Xiaoyong Huang, Shaoying Wang, Bin Li, Qi Sun, Heng Guo
In this work, we reported on high-brightness Eu3+ -activated Ca3 Lu(AlO)3 (BO3 )4 (CLAB) red-emitting phosphors. Under 397 nm excitation, the CLAB:Eu3+ phosphors showed intense red emissions at around 621 nm with CIE coordinates of (0.657, 0.343). The optimal doping concentration of Eu3+ ions was found to be 30 mol. %, and the CLAB:0.3Eu3+ sample possessed high-color purity of 93% and ultra-high internal quantum efficiency as great as 98.5%. Importantly, the CLAB:0.3Eu3+ also had good thermal stability. Finally, a white-light-emitting diode (WLED) lamp with good color-rendering index was fabricated by using a 365 nm ultraviolet chip and the phosphor blends of CLAB:0...
March 15, 2018: Optics Letters
Sencer Ayas, Gokhan Bakan, Erol Ozgur, Kemal Celebi, Gamze Torunoglu, Aykutlu Dana
Metal films covered with ultrathin lossy dielectrics can exhibit strong interference effects manifested as the broad absorption of the incident light resulting in distinct surface colors. Despite their simple bilayer structures, such surfaces have only recently been scrutinized and applied mainly to color printing. Here, we report the use of such surfaces for colorimetric detection of ultrathin dielectrics. Upon deposition of a nanometer-thick dielectric on the surface, the absorption peak red shifts, changing the surface color...
March 15, 2018: Optics Letters
K N Jarvis, J A Devlin, T E Wall, B E Sauer, M R Tarbutt
We present the properties and advantages of a new magneto-optical trap (MOT) where blue-detuned light drives "type-II" transitions that have dark ground states. Using ^{87}Rb, we reach a radiation-pressure-limited density exceeding 10^{11}  cm^{-3} and a temperature below 30  μK. The phase-space density is higher than in normal atomic MOTs and a million times higher than comparable red-detuned type-II MOTs, making the blue-detuned MOT particularly attractive for molecular MOTs, which rely on type-II transitions...
February 23, 2018: Physical Review Letters
Pawel Posadzki, Josip Car
Clinical Question: Are light therapies effective and safe for treating acne? Bottom Line: The evidence for all light therapies remains weak and inconclusive. Red-light methyl aminolevulinate-photodynamic therapy (MAL-PDT) was the only treatment associated with a small though clinically insignificant reduction in the number of inflamed lesions and in global improvement as assessed by an investigator in moderate to severe acne. Red-light MAL-PDT was not associated with higher rates of severe adverse effects than placebo or no treatment...
March 14, 2018: JAMA Dermatology
Anna Lynnyk, Mariia Lunova, Milan Jirsa, Daria Egorova, Andrei Kulikov, Šárka Kubinová, Oleg Lunov, Alexandr Dejneka
Low-power laser irradiation of red light has been recognized as a promising tool across a vast variety of biomedical applications. However, deep understanding of the molecular mechanisms behind laser-induced cellular effects remains a significant challenge. Here, we investigated mechanisms involved in the death process in human hepatic cell line Huh7 at a laser irradiation. We decoupled distinct cell death pathways targeted by laser irradiations of different powers. Our data demonstrate that high dose laser irradiation exhibited the highest levels of total reactive oxygen species production, leading to cyclophilin D-related necrosis via the mitochondrial permeability transition...
March 1, 2018: Biomedical Optics Express
Marcel T Bernucci, Conrad W Merkle, Vivek J Srinivasan
Optical coherence tomography angiography (OCTA) has recently emerged for imaging vasculature in clinical ophthalmology. Yet, OCTA images contain artifacts that remain challenging to interpret. To help explain these artifacts, we perform contrast-enhanced OCTA with a custom-designed wide-field ophthalmoscope in rats in vivo . We choose an intravascular contrast agent (Intralipid) with particles that are more isotropically scattering and more symmetrically shaped than red blood cells (RBCs). Then, by examining how OCTA artifacts change after contrast agent injection, we attribute OCTA artifacts to RBC-specific properties...
March 1, 2018: Biomedical Optics Express
Azeem Ullah, Yuxiang Zhang, Zafar Iqbal, Yaxin Zhang, Dong Wang, Jincan Chen, Ping Hu, Zhuo Chen, Mingdong Huang
Photodynamic antimicrobial chemotherapy (PACT) is considered a promising alternative to conventional antibiotic approach. We have previously developed a novel PS containing five lysine amino acids, pentalysine-β-carbonylphthalocyanine Zinc (ZnPc(Lys)5 ), which in the presence of light, is highly toxic against a range of bacterial strains, including hospital isolated, drug resistant Acinetobacter baumannii. Here, we study the effect of light fluence of the two light sources on the PACT potency of ZnPc(Lys)5 ...
March 1, 2018: Biomedical Optics Express
Angelo Forli, Dania Vecchia, Noemi Binini, Francesca Succol, Serena Bovetti, Claudio Moretti, Francesco Nespoli, Mathias Mahn, Christopher A Baker, McLean M Bolton, Ofer Yizhar, Tommaso Fellin
Sensory information is encoded within the brain in distributed spatiotemporal patterns of neuronal activity. Understanding how these patterns influence behavior requires a method to measure and to bidirectionally perturb with high spatial resolution the activity of the multiple neuronal cell types engaged in sensory processing. Here, we combined two-photon holography to stimulate neurons expressing blue light-sensitive opsins (ChR2 and GtACR2) with two-photon imaging of the red-shifted indicator jRCaMP1a in the mouse neocortex in vivo...
March 13, 2018: Cell Reports
Peter Sykora, Ylenia Chiari, Andrew Heaton, Nickolas Moreno, Scott Glaberman, Robert W Sobol
DNA damage has been linked to genomic instability and the progressive breakdown of cellular and organismal homeostasis, leading to the onset of disease and reduced longevity. Insults to DNA from endogenous sources include base deamination, base hydrolysis, base alkylation, and metabolism-induced oxidative damage that can lead to single-strand and double-strand DNA breaks. Alternatively, exposure to environmental pollutants, radiation or ultra-violet light, can also contribute to exogenously derived DNA damage...
March 14, 2018: Environmental and Molecular Mutagenesis
Jose A Jimenez-Berni, David M Deery, Pablo Rozas-Larraondo, Anthony Tony G Condon, Greg J Rebetzke, Richard A James, William D Bovill, Robert T Furbank, Xavier R R Sirault
Crop improvement efforts are targeting increased above-ground biomass and radiation-use efficiency as drivers for greater yield. Early ground cover and canopy height contribute to biomass production, but manual measurements of these traits, and in particular above-ground biomass, are slow and labor-intensive, more so when made at multiple developmental stages. These constraints limit the ability to capture these data in a temporal fashion, hampering insights that could be gained from multi-dimensional data...
2018: Frontiers in Plant Science
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