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https://www.readbyqxmd.com/read/28520873/association-between-neurocognitive-decline-and-visual-field-variability-in-glaucoma
#1
Alberto Diniz-Filho, Lisa Delano-Wood, Fábio B Daga, Sebastião Cronemberger, Felipe A Medeiros
Importance: Visual field variability may impair detection of glaucoma progression over time. Despite the possible overlap between neurocognitive disorders and glaucoma in older individuals, no study has investigated the association between cognitive changes and visual field variability. Objective: To evaluate the association between global neurocognitive impairment and visual field variability in patients diagnosed as having glaucoma or glaucoma suspects. Design, Setting, and Participants: This prospective observational cohort study was conducted at the Visual Performance Laboratory, University of California, San Diego...
May 18, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28486275/evaluation-of-optic-nerve-head-and-peripapillary-choroidal-vasculature-using-swept-source-optical-coherence-tomography-angiography
#2
Kyeong Ik Na, Won June Lee, Young Kook Kim, Jin Wook Jeoung, Ki Ho Park
PURPOSE: The authors visualized arterioles from the peripapillary choroid to the optic nerve head in vivo, using swept-source optical coherence tomography angiography. METHODS AND RESULTS: In this case series, we present 3 eyes with visible centripetal branches from the peripapillary choroid. The 3 eyes were diagnosed as glaucoma suspect, normal-tension glaucoma, and primary open-angle glaucoma. In the en face projection images of the choroidal layer, obtained by swept-source optical coherence tomography angiography, the vessels from the peripapillary choroid to the optic nerve head were observed in all 3 eyes; one of them was further evaluated by indocyanine green angiography using the Heidelberg retina angiograph...
May 8, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28461014/comparison-of-corneal-biomechanical-properties-between-indian-and-chinese-adults
#3
Jacqueline Chua, Monisha E Nongpiur, Wanting Zhao, Yih Chung Tham, Preeti Gupta, Charumathi Sabanayagam, Tin Aung, Tien Yin Wong, Ching-Yu Cheng
PURPOSE: To investigate the difference in corneal hysteresis (CH) and corneal resistance factor (CRF) between Indian and Chinese populations. DESIGN: Population-based cross-sectional study. PARTICIPANTS: Three hundred eighty-two Singaporean Indian persons and 764 Singaporean Chinese 50 years of age or older were included from the Singapore Indian Eye Study and Singapore Chinese Eye Study, respectively. METHODS: Participants underwent standardized systemic and ocular examinations and interviewer-administered questionnaires for risk factor assessment...
April 28, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28324116/thick-prelaminar-tissue-decreases-lamina-cribrosa-visibility
#4
Katie A Lucy, Bo Wang, Joel S Schuman, Richard A Bilonick, Yun Ling, Larry Kagemann, Ian A Sigal, Ireneusz Grulkowski, Jonathan J Liu, James G Fujimoto, Hiroshi Ishikawa, Gadi Wollstein
Purpose: Evaluation of the effect of prelaminar tissue thickness on visualization of the lamina cribrosa (LC) using optical coherence tomography (OCT). Methods: The optic nerve head (ONH) region was scanned using OCT. The quality of visible LC microstructure was assessed subjectively using a grading system and objectively by analyzing the signal intensity of each scan's superpixel components. Manual delineations were made separately and in 3-dimensions quantifying prelaminar tissue thickness, analyzable regions of LC microstructure, and regions with a visible anterior LC (ALC) boundary...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28263259/head-down-posture-in-glaucoma-suspects-induces-changes-in-iop-systemic-pressure-and-perg-that-predict-future-loss-of-optic-nerve-tissue
#5
Vittorio Porciatti, William J Feuer, Pedro Monsalve, Giacinto Triolo, Luis Vazquez, John McSoley, Lori M Ventura
PURPOSE: To obtain pilot data on posture-induced changes of intraocular pressure (IOP), systemic pressure, and pattern electroretinogram (PERG) predictive of future optic nerve tissue loss glaucoma suspects (GSs). METHODS: Mean peripapillary retinal fiber layer thickness (RNFLT) was measured with optical coherence tomography 2 times/year in 28 GS aged 58±8.9 years over 5.0±0.73 years. All patients had a baseline PERG, IOP, and brachial blood pressure measurements in the seated and -10 degrees head-down-body-tilt (HDT) position...
May 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28251085/short-duration-transient-visual-evoked-potentials-and-color-reflectivity-discretization-analysis-in-glaucoma-patients-and-suspects
#6
Michael Waisbourd, Rebekah H Gensure, Ardalan Aminlari, Sonya B Shah, Nitasha Khanna, Neil Sood, Jeanne Molineaux, Alberto Gonzalez, Jonathan S Myers, L Jay Katz
AIM: To evaluate the use of short-duration transient visual evoked potentials (VEP) and color reflectivity discretization analysis (CORDA) in glaucomatous eyes, eyes suspected of having glaucoma, and healthy eyes. METHODS: The study included 136 eyes from 136 subjects: 49 eyes with glaucoma, 45 glaucoma suspect eyes, and 42 healthy eyes. Subjects underwent Humphrey visual field (VF) testing, VEP testing, as well as peripapillary retinal nerve fiber layer optical coherence tomography imaging studies with post-acquisition CORDA applied...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28243057/cost-and-detection-rate-of-glaucoma-screening-with-imaging-devices-in-a-primary-care-center
#7
Alfonso Anton, Monica Fallon, Francesc Cots, María A Sebastian, Antonio Morilla-Grasa, Sergi Mojal, Xavier Castells
PURPOSE: To analyze the cost and detection rate of a screening program for detecting glaucoma with imaging devices. MATERIALS AND METHODS: In this cross-sectional study, a glaucoma screening program was applied in a population-based sample randomly selected from a population of 23,527. Screening targeted the population at risk of glaucoma. Examinations included optic disk tomography (Heidelberg retina tomograph [HRT]), nerve fiber analysis, and tonometry. Subjects who met at least 2 of 3 endpoints (HRT outside normal limits, nerve fiber index ≥30, or tonometry ≥21 mmHg) were referred for glaucoma consultation...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28211881/a-technician-delivered-virtual-clinic-for-triaging-low-risk-glaucoma-referrals
#8
A Kotecha, J Brookes, P J Foster
PurposeThe purpose of this study is to describe the outcomes of a technician-delivered glaucoma referral triaging service with 'virtual review' of resultant data by a consultant ophthalmologist.Patients and methodsThe Glaucoma Screening Clinic reviewed new optometrist or GP-initiated glaucoma suspect referrals into a specialist ophthalmic hospital. Patients underwent testing by three ophthalmic technicians in a dedicated clinical facility. Data were reviewed at a different time and date by a consultant glaucoma ophthalmologist...
February 17, 2017: Eye
https://www.readbyqxmd.com/read/28196730/globe-axial-length-growth-at-age-5-years-in-the-infant-aphakia-treatment-study
#9
M Edward Wilson, Rupal H Trivedi, David R Weakley, George A Cotsonis, Scott R Lambert
PURPOSE: To report the longitudinal change in axial length (AL) from the time of unilateral cataract surgery at age 1 to 7 months to age 5 years, and to compare AL growth of operated eyes with that of fellow unoperated eyes. DESIGN: Comparative case series. PARTICIPANTS: Infants enrolled in the Infant Aphakia Treatment Study (IATS). METHODS: The AL at baseline and age 5 years and change in AL were analyzed relative to treated versus fellow eye, visual outcome, and treatment modality (contact lens [CL] vs...
May 2017: Ophthalmology
https://www.readbyqxmd.com/read/28164419/applications-of-the-water-drinking-test-in-glaucoma-management
#10
REVIEW
Remo Susanna, Colin Clement, Ivan Goldberg, Marcelo Hatanaka
Intraocular pressure (IOP) peaks and means have been considered important factors for glaucoma onset and progression. However, peak IOP detection depends only on appropriated IOP checks at office visits, whereas the mean IOP requires longitudinal IOP data collection and may be affected by the interval between visits. Also, IOP peak assessment is necessary to verify if the peak pressure of a given patient is in target range, to evaluate glaucoma suspect risk, the efficacy of hypotensive drugs and to detect early loss of IOP control...
February 6, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28081184/intraocular-pressure-lowering-effect-of-latanoprost-is-hampered-by-defective-cervical-lymphatic-drainage
#11
Young Kook Kim, Kyeong Ik Na, Jin Wook Jeoung, Ki Ho Park
PURPOSE: To evaluate whether defects in cervical lymphatic drainage influence the intraocular pressure (IOP)-lowering effect of latanoprost in patients with primary open-angle glaucoma (POAG) who have undergone unilateral radical neck dissection (uRND). METHODS: We enrolled (1) bilateral POAG patients who had started (bilateral) latanoprost (0.005%) monotherapy prior to their uRND and (2) treatment-naïve, bilateral glaucoma suspects (GSs) who had undergone the same surgery...
2017: PloS One
https://www.readbyqxmd.com/read/28028959/comparison-of-visual-field-measurement-with-heidelberg-edge-perimeter-and-humphrey-visual-field-analyzer-in-patients-with-ocular-hypertension
#12
Kamil Kaczorowski, Małgorzata Mulak, Dorota Szumny, Marta Baranowska, Joanna Jakubaszko-Jabłońska, Marta Misiuk-Hojło
BACKGROUND: Glaucoma is a group of eye diseases which result in damage to the optic nerve and vision loss. The most important examination in glaucoma patients is visual field assessment. One of the newer perimeters is Heidelberg Edge Perimeter (HEP). OBJECTIVES: The aim of the study was to compare visual field measurements made with Humphrey II 740 Visual Field (Carl Zeiss Meditec) and Heidelberg Edge Perimeter (HEP) (Heidelberg Engineering). FDF stimulus (flicker defined form) in HEP stimulates magnocellular retinal cells, which are the first to be damaged in the early stage of glaucoma...
September 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/27993484/myocilin-predictive-genetic-testing-for-primary-open-angle-glaucoma-leads-to-early-identification-of-at-risk-individuals
#13
Emmanuelle Souzeau, Kien Hou Tram, Martin Witney, Jonathan B Ruddle, Stuart L Graham, Paul R Healey, Ivan Goldberg, David A Mackey, Alex W Hewitt, Kathryn P Burdon, Jamie E Craig
PURPOSE: To assess the difference in severity of disease in primary open-angle glaucoma (POAG) patients with a Myocilin (MYOC) disease-causing variant who presented through normal clinical pathways (Clinical cases) versus those who were examined following genetic testing (Genetic cases). DESIGN: Retrospective clinical and molecular study. PARTICIPANTS: Seventy-three MYOC mutation carriers identified through the Australian and New Zealand Registry of Advanced Glaucoma...
December 16, 2016: Ophthalmology
https://www.readbyqxmd.com/read/27977480/comparing-the-performance-of-compass-perimetry-with-humphrey-field-analyzer-in-eyes-with-glaucoma
#14
Harsha L Rao, Sharanya Raveendran, Varsha James, Srilakshmi Dasari, Meena Palakurthy, Hemanth B Reddy, Zia S Pradhan, Dhanaraj A S Rao, Narendra K Puttaiah, Sathi Devi
PURPOSE: To evaluate the reliability indices [fixation losses, false negative response rates (FN) and false positive response rates] and threshold sensitivities obtained from glaucoma patients with a Compass perimeter and to compare the same with the Humphrey field analyzer (HFA). METHODS: In a cross-sectional study, 97 eyes of 58 subjects (64 glaucoma and 33 glaucoma suspect eyes) underwent visual field examination with Compass and HFA. Any test with a fixation losses, FN or FP of >20% was considered unreliable...
March 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/27977479/pilot-study-of-lamina-cribrosa-intensity-measurements-in-glaucoma-using-swept-source-optical-coherence-tomography
#15
Sowmya Srinivas, Anna Dastiridou, Mary K Durbin, Muneeswar G Nittala, Alex A Huang, James C H Tan, Brian A Francis, Srinivas R Sadda, Vikas Chopra
PURPOSE: To compare the lamina cribrosa (LC) intensity in glaucoma-suspect eyes and eyes with mild to moderate glaucoma using swept-source optical coherence tomography. METHODS: Optic disc volume scans were collected using swept-source optical coherence tomography in 19 clinically defined glaucoma-suspect eyes and 29 eyes with mild to moderate glaucoma. LC intensity was measured using Image J software, and the resultant values were normalized using the retinal pigment epithelium and vitreous signal...
February 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/27938953/frequency-of-unplanned-interventions-in-patients-attending-for-a-presumed-routine-glaucoma-follow-up-appointment
#16
Jennifer Calafati, Zia S Pradhan, Catherine M Birt
OBJECTIVE: To determine the frequency of patient visits in which an unplanned treatment modification was required in chronic patients attending a glaucoma clinic for routine follow-up and to identify the treatment interventions most commonly employed. DESIGN: Prospective, cross-sectional study. PARTICIPANTS: A total of 630 previously stable patients attending a glaucoma clinic for routine follow-up. METHODS: This was a single-centre survey of all eligible patients returning to an academic glaucoma clinic...
December 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/27898580/resident-compliance-with-the-american-academy-of-ophthalmology-preferred-practice-patterns-for-primary-open-angle-glaucoma-suspect
#17
Melanie Mihlstin, Mark S Juzych, Heidi T Kromrei, Frank S Hwang, Jia Yin
PURPOSE: To study resident compliance with the American Academy of Ophthalmology (AAO) Preferred Practice Patterns (PPPs) for primary open-angle glaucoma suspect (POAGS) in a resident ophthalmology clinic. PATIENTS AND METHODS: Two hundred charts were selected for analysis of adult patients with the International Classification of Diseases diagnosis code for POAGS during their initial visit between November 2, 2010 and May 6, 2014 at the Kresge Eye Institute resident clinic...
December 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27874246/predicting-the-intereye-asymmetry-in-functional-and-structural-damage-in-glaucoma-using-automated-pupillography
#18
Harsha L Rao, Sujatha V Kadambi, Srilakshmi Dasari, Hemanth B Reddy, Meena Palakurthy, Mohammed Riyazuddin, Narendra K Puttaiah, Zia S Pradhan, Dhanaraj A S Rao, Rohit Shetty
PURPOSE: To predict the intereye asymmetry in functional (mean deviation, MD on visual field, VF) and structural (retinal nerve fibre layer, RNFL and ganglion cell complex, GCC thickness on spectral domain optical coherence tomography, SDOCT) measurements in glaucoma using the automated pupillography parameters. METHODS: Fifty-nine subjects with a diagnosis of either glaucoma or glaucoma suspect underwent automated pupillography along with VF and SDOCT examinations...
November 22, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27860477/-ocular-surface-evaluation-in-patients-treated-with-prostaglandin-analogues-considering-preservative-agent
#19
E Mlčáková, P Mlčák, M Karhanová, K Langová, K Marešová
PURPOSE: The aim of this study was to evaluate the ocular surface in patients treated with prostaglandin analogues considering contained preservative agent. METHODS: 60 patients with glaucoma or ocular hypertension treated with prostaglandin analogue monotherapy were enrolled in this observational study. 20 patients with glaucoma suspect or ocular hypertension without local or systemic glaucoma medication formed the control group. Demographic data and medical history were recorded for each participant...
2016: Ceská a Slovenská Oftalmologie
https://www.readbyqxmd.com/read/27828721/change-in-central-corneal-thickness-after-the-discontinuation-of-latanoprost-in-normal-tension-glaucoma-change-in-central-corneal-thickness-after-stop-of-latanoprost
#20
Romi Yoo, Youn A Choi, Byung Joo Cho
PURPOSE: To assess the impact of latanoprost on central corneal thickness (CCT) after ceasing medication in patients with normal tension glaucoma (NTG). METHODS: A total of 46 eyes from 46 NTG patients, and 44 eyes from 44 individuals with glaucoma suspect (controls), were included in this retrospective study. Newly diagnosed early NTG patients (visual field mean deviation >-6.00) were administered latanoprost 0.005% monotherapy once a day. CCTs were measured by ultrasound pachymetry before treatment, for 5 years during treatment, and for 2 years after ceasing treatment...
January 2017: Journal of Ocular Pharmacology and Therapeutics
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