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"Glaucoma suspect"

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https://www.readbyqxmd.com/read/27898580/resident-compliance-with-the-american-academy-of-ophthalmology-preferred-practice-patterns-for-primary-open-angle-glaucoma-suspect
#1
Melanie Mihlstin, Mark S Juzych, Heidi T Kromrei, Frank S Hwang, Jia Yin
PURPOSE: To study resident compliance with the American Academy of Ophthalmology (AAO) Preferred Practice Patterns (PPPs) for primary open-angle glaucoma suspect (POAGS) in a resident ophthalmology clinic. PATIENTS AND METHODS: Two hundred charts were selected for analysis of adult patients with the International Classification of Diseases diagnosis code for POAGS during their initial visit between November 2, 2010 and May 6, 2014 at the Kresge Eye Institute resident clinic...
December 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27874246/predicting-the-intereye-asymmetry-in-functional-and-structural-damage-in-glaucoma-using-automated-pupillography
#2
Harsha L Rao, Sujatha V Kadambi, Srilakshmi Dasari, Hemanth B Reddy, Meena Palakurthy, Mohammed Riyazuddin, Narendra K Puttaiah, Zia S Pradhan, Dhanaraj A S Rao, Rohit Shetty
PURPOSE: To predict the intereye asymmetry in functional (mean deviation, MD on visual field, VF) and structural (retinal nerve fibre layer, RNFL and ganglion cell complex, GCC thickness on spectral domain optical coherence tomography, SDOCT) measurements in glaucoma using the automated pupillography parameters. METHODS: Fifty-nine subjects with a diagnosis of either glaucoma or glaucoma suspect underwent automated pupillography along with VF and SDOCT examinations...
November 22, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27860477/-ocular-surface-evaluation-in-patients-treated-with-prostaglandin-analogues-considering-preservative-agent
#3
E Mlčáková, P Mlčák, M Karhanová, K Langová, K Marešová
PURPOSE: The aim of this study was to evaluate the ocular surface in patients treated with prostaglandin analogues considering contained preservative agent. METHODS: 60 patients with glaucoma or ocular hypertension treated with prostaglandin analogue monotherapy were enrolled in this observational study. 20 patients with glaucoma suspect or ocular hypertension without local or systemic glaucoma medication formed the control group. Demographic data and medical history were recorded for each participant...
2016: Ceská a Slovenská Oftalmologie
https://www.readbyqxmd.com/read/27828721/change-in-central-corneal-thickness-after-the-discontinuation-of-latanoprost-in-normal-tension-glaucoma-change-in-central-corneal-thickness-after-stop-of-latanoprost
#4
Romi Yoo, Youn A Choi, Byung Joo Cho
PURPOSE: To assess the impact of latanoprost on central corneal thickness (CCT) after ceasing medication in patients with normal tension glaucoma (NTG). METHODS: A total of 46 eyes from 46 NTG patients, and 44 eyes from 44 individuals with glaucoma suspect (controls), were included in this retrospective study. Newly diagnosed early NTG patients (visual field mean deviation >-6.00) were administered latanoprost 0.005% monotherapy once a day. CCTs were measured by ultrasound pachymetry before treatment, for 5 years during treatment, and for 2 years after ceasing treatment...
November 9, 2016: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/27818206/automated-segmentation-errors-when-using-optical-coherence-tomography-to-measure-retinal-nerve-fiber-layer-thickness-in-glaucoma
#5
Steven L Mansberger, Shivali Menda, Brad Fortune, Stuart K Gardiner, Shaban Demirel
PURPOSE: To characterize the error of optical coherence tomography (OCT) measurements of retinal nerve fiber layer (RNFL) thickness when using automated retinal layer segmentation algorithms without manual refinement. DESIGN: cross-sectional study METHODS: Setting: glaucoma clinical practice. STUDY POPULATION: 3490 scans from 412 eyes of 213 individuals with a diagnosis of glaucoma or glaucoma suspect. Observational Procedures: We used spectral domain OCT (Spectralis, Heidelberg Engineering, Heidelberg, Germany) to measure RNFL thickness in a 6-degree peripapillary circle, and exported the native 'automated segmentation only' results...
November 3, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27788183/angle-closure-scoring-system-acss-a-scoring-system-for-stratification-of-angle-closure-disease
#6
Aparna Rao, Debananda Padhy, Sarada Sarangi, Gopinath Das
PURPOSE: To evaluate the angle closure scoring system (ACSS) for stratifying primary angle course disease. METHODS: This observational cross sectional institutional study included patients with primary open angle glaucoma suspects (n = 21) and primary angle closure disease (primary angle closure, PAC, n = 63 and primary angle course glaucoma, PACG, n = 58 (defined by International society of Geographical and Epidemiological Ophthalmology, ISGEO). Two independent examiners blinded to clinical details, graded good quality pre-laser goniophotographs of the patients incorporating quadrants of peripheral anterior synechieae (PAS), non-visibility of posterior trabecular meshwork (PTM) and blotchy pigments (ranging from 1-4 quadrants), iris configuration, angle recess (sum of above depicting ACSSg) and lens thickness/axial length ratio (LT/AL), cup disc ratio and baseline intraocular pressure (IOP) to give total score (ACSSt)...
2016: PloS One
https://www.readbyqxmd.com/read/27782956/predictive-value-of-hrt-stereometric-parameters-and-blue-on-yellow-perimetry-global-indices-in-glaucoma-suspected-subjects
#7
Konstantinos Rallis, George D Kymionis, Ilias Georgalas, Marilita M Moschos, Chryssanthi Koutsandrea, Michael A Grentzelos, Dimitris Papaconstantinou
OBJECTIVE: To determine subtle changes of Heidelberg retina tomography (HRT) stereometric parameters and blue-on-yellow (B/Y) perimetry global indices for the early diagnosis of glaucoma in suspected subjects. PATIENTS AND METHODS: Cross-sectional data on 174 eyes of 87 subjects from a larger cohort, attending the Glaucoma Department of the "G. Gennimatas" General Hospital of Athens from January 2004 to February 2014, were used in the study. Subjects were assigned to 3 groups: (a) "normals" not requiring treatment throughout the study (group 1), (b) suspects who developed glaucoma and required treatment during the study (group 2), and (c) patients with incipient glaucoma (group 3)...
December 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27764022/central-corneal-thickness-in-glaucoma
#8
Chelvin C A Sng, Marcus Ang, Keith Barton
PURPOSE OF REVIEW: The purpose of this review is to summarize the role of central corneal thickness (CCT) in the clinical management of a glaucoma patient. RECENT FINDINGS: The prognostic value of CCT is well recognized in patients with ocular hypertension. However, its predictive value in other glaucoma suspects and patients with established glaucoma is less certain. Tonometry artefacts can result from variations in CCT. However, an adequately validated correction algorithm for Goldmann applanation tonometry measurements does not exist...
October 19, 2016: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/27726964/relationship-between-optical-coherence-tomography-angiography-vessel-density-and-severity-of-visual-field-loss-in-glaucoma
#9
Adeleh Yarmohammadi, Linda M Zangwill, Alberto Diniz-Filho, Min Hee Suh, Siamak Yousefi, Luke J Saunders, Akram Belghith, Patricia Isabel C Manalastas, Felipe A Medeiros, Robert N Weinreb
PURPOSE: To evaluate the association between vessel density measurements using optical coherence tomography angiography (OCT-A) and severity of visual field loss in primary open-angle glaucoma. DESIGN: Observational, cross-sectional study. PARTICIPANTS: A total of 153 eyes from 31 healthy participants, 48 glaucoma suspects, and 74 glaucoma patients enrolled in the Diagnostic Innovations in Glaucoma Study. METHODS: All eyes underwent imaging using OCT-A (Angiovue; Optovue, Fremont, CA), spectral-domain OCT (Avanti; Optovue), and standard automated perimetry (SAP)...
October 7, 2016: Ophthalmology
https://www.readbyqxmd.com/read/27698551/short-wave-automated-perimetry-swap-versus-optical-coherence-tomography-in-early-detection-of-glaucoma
#10
Adel Galal Zaky, Ahmed Tarek Yassin, Saber Hamed El Sayid
OBJECTIVE: To assess the role and diagnostic effectiveness of optical coherence tomography (OCT) and short wave-automated perimetry (SWAP) to distinguish between normal, glaucoma suspects, and surely diagnosed glaucomatous eye. BACKGROUND: Changes in the optic disc and retinal nerve fiber layer (RNFL) often precede the appearance of visual field defect with standard automated perimetry. Unfortunately, RNFL defect can be difficult to identify during clinical examination...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27689896/atlas-based-shape-analysis-and-classification-of-retinal-optical-coherence-tomography-images-using-the-functional-shape-fshape-framework
#11
Sieun Lee, Nicolas Charon, Benjamin Charlier, Karteek Popuri, Evgeniy Lebed, Marinko V Sarunic, Alain Trouvé, Mirza Faisal Beg
We propose a novel approach for quantitative shape variability analysis in retinal optical coherence tomography images using the functional shape (fshape) framework. The fshape framework uses surface geometry together with functional measures, such as retinal layer thickness defined on the layer surface, for registration across anatomical shapes. This is used to generate a population mean template of the geometry-function measures from each individual. Shape variability across multiple retinas can be measured by the geometrical deformation and functional residual between the template and each of the observations...
September 20, 2016: Medical Image Analysis
https://www.readbyqxmd.com/read/27622679/quadrant-field-pupillometry-detects-melanopsin-dysfunction-in-glaucoma-suspects-and-early-glaucoma
#12
Prakash Adhikari, Andrew J Zele, Ravi Thomas, Beatrix Feigl
It is difficult to detect visual function deficits in patients at risk for glaucoma (glaucoma suspects) and at early disease stages with conventional ophthalmic tests such as perimetry. To this end, we introduce a novel quadrant field measure of the melanopsin retinal ganglion cell mediated pupil light response corresponding with typical glaucomatous arcuate visual field defects. The melanopsin-mediated post-illumination pupil response (PIPR) was measured in 46 patients with different stages of glaucoma including glaucoma suspects and compared to a healthy group of 21 participants with no disease...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27554036/association-between-intraocular-pressure-and-rates-of-retinal-nerve-fiber-layer-loss-measured-by-optical-coherence-tomography
#13
Alberto Diniz-Filho, Ricardo Y Abe, Linda M Zangwill, Carolina P B Gracitelli, Robert N Weinreb, Christopher A Girkin, Jeffrey M Liebmann, Felipe A Medeiros
PURPOSE: To evaluate the relationship between intraocular pressure (IOP) and rates of retinal nerve fiber layer (RNFL) thickness change over time measured by spectral-domain (SD) optical coherence tomography (OCT). DESIGN: Observational cohort study. PARTICIPANTS: The study involved 547 eyes of 339 patients followed up for an average of 3.9±0.9 years. Three hundred eight (56.3%) had a diagnosis of glaucoma and 239 (43.7%) were considered glaucoma suspects...
October 2016: Ophthalmology
https://www.readbyqxmd.com/read/27483331/vision-related-quality-of-life-in-glaucoma-suspect-or-early-glaucoma-patients
#14
Asem Alqudah, Steven L Mansberger, Stuart K Gardiner, Shaban Demirel
PURPOSE: To determine the association of vision-related quality of life (QoL) to demographic factors and visual function in glaucoma suspect or early glaucoma patients. MATERIALS AND METHODS: We administered the 25-item National Eye Institute Visual Function Questionnaire (VFQ-25) on the same day as a comprehensive ocular examination to participants either with glaucoma or at high risk for developing glaucoma. Regression models were used to determine the association between VFQ-25 composite and subscale scores, visual field status, logMAR equivalent visual acuity (VA), age, and sex...
August 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27480527/repeatability-of-heidelberg-retinal-tomography-3-and-effect-of-alignment-algorithm-on-glaucoma-suspects
#15
Nayuta Yoshioka, Elizabeth Wong, Michael Kalloniatis, Barbara Zangerl
BACKGROUND: The Heidelberg Retina Tomograph (HRT) is a commonly-used clinical instrument for glaucoma diagnosis; however, the repeatability of the two most commonly used analysis tools, Moorfield regression analysis (MRA) and 'glaucoma probability score' (GPS) is not known and could have significant implications for patients at risk or suspected of developing glaucoma. Thus, the intra-visit repeatability of the HRT3 (an objective measure of instrument-induced variability) was investigated in a glaucoma suspect cohort...
August 1, 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/27470061/quantitative-optical-coherence-tomography-angiography-of-radial-peripapillary-capillaries-in-glaucoma-glaucoma-suspect-and-normal-eyes
#16
Zaid Mammo, Morgan Heisler, Chandrakumar Balaratnasingam, Sieun Lee, Dao-Yi Yu, Paul Mackenzie, Steven Schendel, Andrew Merkur, Andrew Kirker, David Albiani, Eduardo Navajas, Mirza Faisal Beg, William Morgan, Marinko V Sarunic
PURPOSE: To evaluate the quantitative characteristics of the radial peripapillary capillary (RPC) network in glaucoma, glaucoma suspect, and normal eyes using speckle variance optical coherence tomography angiography (OCT-A). To determine correlations between RPC density, nerve fiber layer (NFL) thickness, and visual field indices. DESIGN: Cross-sectional study. METHODS: OCT-A images of RPCs were acquired at a single institution using a custom-built 1060 nm system from 3 groups: unilateral glaucoma (10 eyes from 5 subjects), glaucoma suspects (6 eyes from 3 subjects), and normal control eyes (16 eyes from 9 normal subjects)...
October 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27442341/peripapillary-retinal-nerve-fiber-layer-vascular-microcirculation-in-glaucoma-using-optical-coherence-tomography-based-microangiography
#17
Chieh-Li Chen, Anqi Zhang, Karine D Bojikian, Joanne C Wen, Qinqin Zhang, Chen Xin, Raghu C Mudumbai, Murray A Johnstone, Philip P Chen, Ruikang K Wang
PURPOSE: To investigate the vascular microcirculation changes in the retinal nerve fiber layer (RNFL) in normal, glaucoma suspect, and open-angle glaucoma (OAG) groups using optical coherence tomography-based microangiography (OMAG). METHODS: One eye from each subject was scanned with a Cirrus HD-OCT 5000-based OMAG prototype system montage scanning protocol centered at the optic nerve head (ONH). Blood flow signals were extracted using OMAG algorithm. Retinal nerve fiber layer vascular microcirculation was measured by calculating the blood flux index and vessel area density within a 1...
July 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27433805/eyes-with-suspicious-appearance-of-the-optic-disc-and-normal-intraocular-pressure-using-clinical-and-epidemiological-characteristics-to-differentiate-those-with-and-without-glaucoma
#18
Diego T Dias, Michele Ushida, Marina C Sousa, Syril Dorairaj, Luis G Biteli, Mauro T Leite, Augusto Paranhos, Tiago S Prata
Among all glaucoma suspects, eyes with optic nerve head features suspicious or suggestive of early glaucoma are probably those that offer the greatest challenge for clinicians. In contrast with the robust longitudinal data published on ocular hypertension, there is no specific management guideline for these patients. Therefore, evaluating eyes with suspicious optic disc appearance and normal intraocular pressure (IOP), we sought to investigate potential differences in clinical and epidemiological characteristics to differentiate those with normal-tension glaucoma (NTG) from those with presumed large physiological optic disc cups (pLPC)...
2016: PloS One
https://www.readbyqxmd.com/read/27419859/structure-function-relationship-between-flicker-defined-form-perimetry-and-spectral-domain-optical-coherence-tomography-in-glaucoma-suspects
#19
Lukas Reznicek, Daniel Muth, Michaela Vogel, Christoph Hirneiß
PURPOSE: To evaluate the relationship between functional parameters of repeated flicker-defined form perimetry (FDF) and structural parameters of spectral-domain optical coherence tomography (SD-OCT) in glaucoma suspects with normal findings in achromatic standard automated perimetry (SAP). METHODS: Patients with optic nerve heads (ONH) clinically suspicious for glaucoma and normal SAP findings were enrolled in this prospective study. Each participant underwent visual field (VF) testing with FDF perimetry, using the Heidelberg Edge Perimeter (HEP, Heidelberg Engineering, Heidelberg, Germany) at two consecutive visits...
July 15, 2016: Current Eye Research
https://www.readbyqxmd.com/read/27409509/technology-and-the-glaucoma-suspect
#20
Dana M Blumberg, Carlos Gustavo De Moraes, Jeffrey M Liebmann, Reena Garg, Cynthia Chen, Alex Theventhiran, Donald C Hood
PURPOSE: To determine and compare the diagnostic performance of spectral-domain optical coherence tomography (SD-OCT), stereoscopic disc photographs, and automated perimetry as assessed by a group of glaucoma specialists in differentiating individuals with early glaucoma from suspects. METHODS: Forty-six eyes (46 patients) with suspicious optic nerves had previously undergone SD-OCT scans, 24-2 visual fields (VFs), and optic disc photographs. The average VF mean deviation was -1...
July 1, 2016: Investigative Ophthalmology & Visual Science
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